LOCUS       NC_019673              21083 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Saccharothrix espanaensis DSM 44229, complete sequence.
ACCESSION   NC_019673
VERSION     NC_019673.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Saccharothrix espanaensis DSM 44229
  ORGANISM  Saccharothrix espanaensis DSM 44229
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Saccharothrix.
REFERENCE   1
  AUTHORS   Strobel,T., Al-Dilaimi,A., Blom,J., Gessner,A., Kalinowski,J.,
            Luzhetska,M., Puhler,A., Szczepanowski,R., Bechthold,A. and
            Ruckert,C.
  TITLE     Complete genome sequence of Saccharothrix espanaensis DSM 44229(T)
            and comparison to the other completely sequenced Pseudonocardiaceae
  JOURNAL   BMC Genomics 13, 465 (2012)
   PUBMED   22958348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9360653)
  AUTHORS   Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2012) IGS, CeBiTec, Bielefeld University,
            Universitaetsstr. 27, D-33335, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000328705.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:06:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,451
            Genes (coding)                    :: 8,313
            CDSs (with protein)               :: 8,313
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 43 of 138
            Pseudo Genes (incomplete)         :: 116 of 138
            Pseudo Genes (internal stop)      :: 7 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:45:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6944767
            Orig. end                         :: 6965850
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE804045.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="33"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11083
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(260..273)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    834..849
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.83"
                     /tool="antismash"
     gene            complement(1710..3284)
                     /locus_tag="BN6_RS29930"
                     /old_locus_tag="BN6_62190"
     CDS             complement(1710..3284)
                     /codon_start=1
                     /function="dGTP triphosphohydrolase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103580.1"
                     /locus_tag="BN6_RS29930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62190"
                     /product="deoxyguanosinetriphosphate triphosphohydrolase
                     family protein"
                     /protein_id="WP_015103580.1"
                     /transl_table=11
                     /translation="MHREHADPRALRRSGMDASTPLQSDLATSPFRVDRDRVASSPFFA
                     RLGGVTQVVSSTGSGLLVHNRLTHSLKVAQAARAIAERLGARPELVGVLDKLGGCDPDV
                     VEAAALAHDLGHPPFGHLGEQVLDRLARHRFGLSDGFEGNAQSFRIVTTTDVRGPAAVG
                     LDLTVAVRAAMLKYPWTRLSYPKPHPKDLRVPPRGAAEPPDAPGTGAAKFSAYVTELDD
                     LTQARAFYAGRVEPWQQTVEASVMDTADDIAYAIHDLEDFYRVGVLQHATVSTELNTWL
                     DHAVDLAGISAADLAAQERQPGRSLEALRRRLHLKDSWAVDDDAFAQAVAMVRTELVGG
                     LLAVPFDGSVEAEQAVAAFSARWTRRLVDAVGVLDEPSTRSGHVVLAVQQWHEVQVLKF
                     VHRRFVLLRPDLALHQRGQARLLTALVEALEQWATDRHEADRLPRRLHDLIELATSEYT
                     ALARTDPSSLVGATGDTPSGPDAVRALARGRAVVDFVASLTDNQAAALLDALSGRTGQL
                     WTDAFVL"
     misc_feature    complement(3329..3344)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.34"
                     /tool="antismash"
     misc_feature    complement(3373..3386)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.87"
                     /tool="antismash"
     rRNA            complement(3382..3498)
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="BN6_RS29935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="BN6_62193"
                     /product="5S ribosomal RNA"
     gene            complement(3382..3498)
                     /gene="rrf"
                     /locus_tag="BN6_RS29935"
                     /old_locus_tag="BN6_62193"
     rRNA            complement(3613..6692)
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="BN6_RS29940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="BN6_62195"
                     /product="23S ribosomal RNA"
     gene            complement(3613..6692)
                     /locus_tag="BN6_RS29940"
                     /old_locus_tag="BN6_62195"
     misc_feature    complement(4493..4513)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    complement(4582..4595)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.96"
                     /tool="antismash"
     misc_feature    4723..4732
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    4725..4738
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.03"
                     /tool="antismash"
     misc_feature    4726..4739
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.1"
                     /tool="antismash"
     misc_feature    complement(4728..4741)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.92"
                     /tool="antismash"
     misc_feature    complement(5933..5948)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.58"
                     /tool="antismash"
     misc_feature    complement(6722..6731)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     rRNA            complement(7046..8561)
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="BN6_RS29945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="BN6_62197"
                     /product="16S ribosomal RNA"
     gene            complement(7046..8561)
                     /locus_tag="BN6_RS29945"
                     /old_locus_tag="BN6_62197"
     misc_feature    complement(7453..7470)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    7974..7986
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(8077..8097)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.62"
                     /tool="antismash"
     misc_feature    complement(8128..8144)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.97"
                     /tool="antismash"
     misc_feature    8438..8455
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(8502..8518)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     misc_feature    complement(8668..8682)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.24"
                     /tool="antismash"
     misc_feature    complement(8701..8710)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            9027..10001
                     /locus_tag="BN6_RS29950"
                     /old_locus_tag="BN6_62210"
     CDS             9027..10001
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103581.1"
                     /locus_tag="BN6_RS29950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62210"
                     /product="MASE1 domain-containing protein"
                     /protein_id="WP_041314537.1"
                     /transl_table=11
                     /translation="MLLSPRLRPWGRYGIHLAVVAACYYAGARLGLLQALVNDQVTPLW
                     PPTGVALLALMLGGVRMWPGIAVAAFVVNATLGDSSSAFLISVGNTLGPVVAFLLLKHS
                     GFRLEIDRARDALTFVFLGAFVGMAVSATIGTGALLLSGSVGWPDFWATWSVWWTGDAM
                     GVLILVPLVLALRGLRFPVRSARAWEAAALLTSTTGVMLIAASSPLRLLYLVFPFAIWG
                     ALRFQHLGAAPCALIATVLAARGAAAGIGPFANLDLLQRMVTLQAFNGTVALTTLVLSA
                     VISERNAARRAIERTCAQLTDVVEAYRPLLLGNGVRPEPPDGR"
     gene            10001..11083
                     /locus_tag="BN6_RS29955"
                     /old_locus_tag="BN6_62220"
     CDS             10001..11083
                     /codon_start=1
                     /function="2-polyprenyl-6-methoxyphenol hydroxylase and
                     related FAD-dependent oxidoreductases"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103582.1"
                     /locus_tag="BN6_RS29955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62220"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_015103582.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 3.6e-48, bitscore:
                     163.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVLIVGGGPAGRALASACSARGLVTSLVDPHPGRPWRATYAAWA
                     DELPVDAPVAVSTSKARVFATSEHRIARGYAVLDNERLRRLPDDVRVVRGLVAERGRRH
                     VVLRDGRVLRAGLVVDATGASGRVAQHAVGVVVAAEQALPFVVDDEALVMDWRRPPDAG
                     SPDPTFLYAIPMPGGGVLLEETSLARGPGLPLPELRLRLRARLAAHGVALPHDEERVRI
                     PLAARPRRGAFGAAAGLVHPATGYSVAEALALAPEVARAIADGVPVDRVVWPARARAVH
                     ALRRYGLAALLVMRPDQVPEFFDLFFHLPENKQRMYLSGRSDLHGTVSAMSALFRTADW
                     RMRARLAFTVQPAKAVRTPG"
     gene            11126..12829
                     /locus_tag="BN6_RS29960"
                     /old_locus_tag="BN6_62230"
     CDS             11126..12829
                     /codon_start=1
                     /function="FOG: EAL domain"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103583.1"
                     /locus_tag="BN6_RS29960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62230"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_015103583.1"
                     /transl_table=11
                     /translation="MPALLDDVRFAFQPLFNLNTGGVVAVEALARPHDGSVQDLLRMAF
                     RAGYLANTDVALACRAIRSAADHDFTLPLHVNLLAMTIADKSEHMAPLYAALRDAGRPT
                     ANLVIEVGTPYSRAPRHRLVKGLDRLRQDGFKIGLDGVGEGDAPLSLLAEVQPEVVKLD
                     REVVQELVDDPARFALVQGLQHLCEATGSLIVAEGVETEPQLAALRRLGVRLAQGNLLA
                     AAQRRPKINATISTVLSEVNDPEAATKTTTKPLRRKPGPKVTDFLHPATTLPESATSED
                     VRDVLATQPTVTGVVLVDDDGRPTWTVDRNRFLLAVTGPFGHALHAKREAARLADPPRV
                     IGAGSTAMEMLDVVAHTNRERTNDDLVVVDDDDRCVGVVRVADVVRGIAEMKVEQAAAL
                     SPLTRLPGSDSIAREVDRRILSGEIFAVGWLDVDAFKRVNDSVGFAAGDDLIRALGRKL
                     TEGATAFPGIQVGHVGGDDFLVVAGLNEVVPYAAGVLDTPFDAEGHAVTLSLATLVCAA
                     GSVGSYREVSRLLAPLKEHAKSLRGNSWVLGRPGSDHVDVLRGGAHLAVS"
     misc_feature    12485..12487
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12920..14038
                     /locus_tag="BN6_RS29965"
                     /old_locus_tag="BN6_62240"
     CDS             12920..14038
                     /EC_number="6.3.2.2"
                     /GO_function="GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042398 - modified amino acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /function="Uncharacterized conserved protein"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1165: carboxylate-amine ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103584.1"
                     /locus_tag="BN6_RS29965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62240"
                     /product="glutamate--cysteine ligase"
                     /protein_id="WP_015103584.1"
                     /transl_table=11
                     /translation="MSEVDVSALPRPRTEFDPALSVGVEEEFLLVDAVTGALSPVAGEV
                     LGDADGVLDLQSEMTRYQVESATAVCWSMDEVREQLVLSRRALGDLAKGHDARIVATGT
                     PVLGGSRPPPLTDRQRYRDIEHRYGSLIDALTICGCHVHIGIPDEETGVLISNHLRQWL
                     PVLLAISANSPFSEGRDTGYASWRYLSWSPWPSAGAPPWFASVEDYHLGTRTLRTSGAA
                     MDTGMIYWDVRLSASHPTVELRVCDVAATVEEAVLIAAIARAIAVVAVSGAAAFPVSDL
                     ALRAALWRAARDGVEGAGVEPHTGRLVAAADLVRTLVEWIRPALRACGDEALVDDGVGR
                     LLLDGCGATRQRRAFTRRGELADVVAMLVAQT"
     gene            14068..15033
                     /locus_tag="BN6_RS29970"
                     /old_locus_tag="BN6_62250"
     CDS             14068..15033
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103585.1"
                     /locus_tag="BN6_RS29970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62250"
                     /product="hypothetical protein"
                     /protein_id="WP_015103585.1"
                     /transl_table=11
                     /translation="MDDVVLGSVTCPSGHLVLVDGGYLRLWSAQRSPDESGGDAAVDFE
                     VVGSDADAAARSFDHQAGRRLYDIPEHAVVPFTAKFDEHCRAGGFGASLRPFPRRVPHR
                     DRVRHALEAGDPEFLITGVPVVPIGGVPTGRALRVVATRGQWGWARIRIELGGGTVVER
                     RPLGTIRVDHARFAFADADALGSWVHDDPLDGLADVVFWGGDEDAIAEEFEARRTRTPG
                     DDTFGWVDLPVREAYRLAVALEERRGVAPERRFAVDFRPHSHHWQAMRAVRASEHEAAT
                     LAVGGADVMLAMTSVGDGFFPAHLDVDAAGAPVAVEIDLS"
     gene            complement(15523..15939)
                     /locus_tag="BN6_RS29980"
                     /old_locus_tag="BN6_62270"
     CDS             complement(15523..15939)
                     /codon_start=1
                     /function="Predicted metal-sulfur cluster biosynthetic
                     enzyme"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103587.1"
                     /locus_tag="BN6_RS29980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62270"
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="WP_015103587.1"
                     /transl_table=11
                     /translation="MTTPEGSTAEHTDEVVRGVEGMPEPPAPKADLPSLDDLEEAMRDV
                     VDPELGINVVDLGLVYDIRVDDDNVALIDMTLTSAACPLTDVIEDQTRTALTGGPGGGI
                     VNDFRINWVWMPPWGPEKITDDGREQLRALGFTV"
     gene            complement(15936..16379)
                     /gene="sufU"
                     /locus_tag="BN6_RS29985"
                     /old_locus_tag="BN6_62280"
     CDS             complement(15936..16379)
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /function="NifU-like protein, involved in Fe-S cluster
                     formation"
                     /gene="sufU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103588.1"
                     /locus_tag="BN6_RS29985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62280"
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="WP_015103588.1"
                     /transl_table=11
                     /translation="MQLQQMYQEIILDHYKNPHGRGLRDPFDAESHQINPTCGDEVTLR
                     VKLDGDKVADVSYDGQGCSISQASTSVLTDLVVGRPVGEAFQKLDAFVELMQGRGKVEP
                     DEDVLEDGIAFAGVAKYPARVKCALLGWMAFKDAVARSEGATA"
     gene            complement(16380..17660)
                     /locus_tag="BN6_RS29990"
                     /old_locus_tag="BN6_62290"
     CDS             complement(16380..17660)
                     /EC_number="2.8.1.7"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (30-411). E-value: 2.4e-140.
                     Score: 459.6. Matches aSDomain:
                     nrpspksdomains_BN6_RS29990_Aminotran_5.1"
                     /codon_start=1
                     /function="Selenocysteine lyase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103589.1"
                     /locus_tag="BN6_RS29990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62290"
                     /product="cysteine desulfurase"
                     /protein_id="WP_015103589.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.9e-140, bitscore:
                     464.8, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-08,
                     bitscore: 33.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAAPLDVATVRADFPILGRTVREGKRLVYLDSGATSQRPRQV
                     LDAERAFLETANAAVHRGAHQLAEEATDAYEGARAKIAAFVGVDFGEIVFTKNATEGVN
                     LVAYAMGNASVAGPEAERFRIGPGDEIVVTEMEHHANLVPWQQLAQRTGATLRWFGVTD
                     EGRLDLSDVDSLITGRTKVVALTHQSNVLGTVNPVRSIVDRARAVGALTVLDACQSVPH
                     GPVDFRALGVDFAVFSGHKMLGPSGVGVLYGRRELLETLPPFLTGGSMIEMVQMASSTF
                     APPPQRFEAGVPMTSQAVALGAAVDYLSEIGMDRVAAHEHVLTEAALRGLAEIPGVRIV
                     GPLDTQDRGGAVSFVVEGIHAHDVGQVLDSLGIAVRVGHHCAWPLHRRLGAAATVRASF
                     YLYNTLDEVRALVEGVREAQKFFGVVA"
     aSDomain        complement(16428..17570)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN6_RS29990_Aminotran_5.1"
                     /evalue="2.40E-140"
                     /label="BN6_RS29990_Aminotran_5.1"
                     /locus_tag="BN6_RS29990"
                     /protein_end="411"
                     /protein_start="30"
                     /score="459.6"
                     /tool="antismash"
                     /translation="VYLDSGATSQRPRQVLDAERAFLETANAAVHRGAHQLAEEATDAY
                     EGARAKIAAFVGVDFGEIVFTKNATEGVNLVAYAMGNASVAGPEAERFRIGPGDEIVVT
                     EMEHHANLVPWQQLAQRTGATLRWFGVTDEGRLDLSDVDSLITGRTKVVALTHQSNVLG
                     TVNPVRSIVDRARAVGALTVLDACQSVPHGPVDFRALGVDFAVFSGHKMLGPSGVGVLY
                     GRRELLETLPPFLTGGSMIEMVQMASSTFAPPPQRFEAGVPMTSQAVALGAAVDYLSEI
                     GMDRVAAHEHVLTEAALRGLAEIPGVRIVGPLDTQDRGGAVSFVVEGIHAHDVGQVLDS
                     LGIAVRVGHHCAWPLHRRLGAAATVRASFYLYNTLDEVRAL"
     gene            complement(17709..18482)
                     /gene="sufC"
                     /locus_tag="BN6_RS29995"
                     /old_locus_tag="BN6_62300"
     CDS             complement(17709..18482)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type transport system involved in Fe-S
                     cluster assembly, ATPase component"
                     /gene="sufC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103590.1"
                     /locus_tag="BN6_RS29995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62300"
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="WP_015103590.1"
                     /transl_table=11
                     /translation="MATLEIKDLHVSVTTDETSKEILKGVDLTIKAGETHAIMGPNGSG
                     KSTLSYAIAGHPKYRITSGTVTLDGEDVLEMSVDERARAGLFLAMQYPVEVPGVSMSNF
                     LRTAATAVRGEAPALRHWVKEVKGAMADLDIDPAFAERSVNEGFSGGEKKRHEILQLGL
                     LKPKIAILDETDSGLDVDALRVVSEGVNKFKESGEAGVMLITHYTRILKYIQPDFVHVF
                     ANGRIVESGGRELADQLEEHGYVKYAGVQEAAKVG"
     gene            complement(18534..18866)
                     /locus_tag="BN6_RS30000"
                     /old_locus_tag="BN6_62310"
     CDS             complement(18534..18866)
                     /codon_start=1
                     /function="Phenylpropionate dioxygenase and related
                     ring-hydroxylating dioxygenases, large terminal subunit"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103591.1"
                     /locus_tag="BN6_RS30000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62310"
                     /product="non-heme iron oxygenase ferredoxin subunit"
                     /protein_id="WP_015103591.1"
                     /transl_table=11
                     /translation="MIRVCSLTDLDDRKPVAFEVGDEYTPVLLVRDGGSVHALRDLCSH
                     AEVALSEGDVTRKGVECWLHGSCFDLRTGRPSSPPATEPVDVFAVDIRDGDVYVDVTAT
                     LNATTN"
     gene            complement(18863..20035)
                     /gene="sufD"
                     /locus_tag="BN6_RS30005"
                     /old_locus_tag="BN6_62320"
     CDS             complement(18863..20035)
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type transport system involved in Fe-S
                     cluster assembly, permease component"
                     /gene="sufD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015103592.1"
                     /locus_tag="BN6_RS30005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_62320"
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="WP_015103592.1"
                     /transl_table=11
                     /translation="MAVTTQDQHGLTAHSHGAGAPISSRADHFASFDVDAFEVPGGREE
                     IWRFTPMKRLAGLHTGVPATGTATVEVKAAEGVRVETAARGDERLGTAGTPADRIAAQA
                     WNSFAEATVITLPKDTKVEPTTVTVTGAGKGEVAYGHLQVRAEQFAEAVVVIDHRGSGA
                     YADNVEFVVADGAHLTVVAIQDWADDAVHVSAHHAKLGRDATFKHTVITLGGDLVRLTP
                     VVTYTGRGGDAELLGLYFADAGQHLEHRTFIDHAVSNCRSNVVYKGALQGEDAHTVWIG
                     DVLIRAAAEGTETFELNRNLVLTDGARADSVPNLEIETGEIEGAGHASATGRFDDEQLF
                     YLQARGIPEEQARRLVVRGFFHEILLKIAVPEVRERLEAAIEAELEAVGV"
     misc_feature    complement(20185..20199)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
ORIGIN
        1 caggtcgtac ggcagcgggt tgttcgccgg ggccgccgcg accgagatgg cgcccttggc
       61 cgccgagtgg ccgcgggtca cgccgggggt ggcgaacttc ttgagcccgt cggacgagtc
      121 cttgaaccgg ccgccgagcg cggacagcgc gaggtacttg ttctcgccgc ggaacttcac
      181 cacggccagc cgcaggccgg aggcggtgcc ggcggtcggc gtctggaccc gctcgtacgg
      241 gtcctgggtg ccgtcctggt tgttctggct gaacgccacg acgttgccct ggccgttgga
      301 cacgtacagg tcgtagtcgt tgaacgacga cccgagcggg tcggaccaga acagcgtcac
      361 cggcacgttg ccggagttcg ccgagagcgg gttgaacacc tgcttggcgt tcgggtcggg
      421 gttgaagtcg tgggcggtgc ccgcgaactt gccgatgccc acgcccgagt cgacgaagtc
      481 gccttcccag tgcccggacg tgccttcggc gacgttgccc tcgttcccgg cggaggagaa
      541 gaacaccgcg ccgtcggcgg tgaccgcgtc cacggcctgg gctatcacgc cgtcctggaa
      601 tggcgactcg ttgaagtaga ggatgtcgtc cacgatcacg tcgcagccga gccggaaccg
      661 gagcgctcgg atgttgtccg cgaagctggc gtcgccgttg accgcggtcg cgaagccgag
      721 ctcggcgttg ggcgcgatgt cgtggaggat ctccagcatc gcggtgccct cgtcaccgga
      781 accttcctgg ctggtcagaa cgtccacggc gggcagctcc cccgccgcct gcgacgccgc
      841 cagcgaactc acgccgtcgg acagcgcgca cagcttcacg ccggtgccgg tgacccgatg
      901 tgtctgccgg gcggtgtctg cggcgtgcgc ccggtcccct tcgccgatct tcgcggcggc
      961 gaccttcggc gagtcgagcg cctcacgggt gcgggcctcg acctccttgg ccttgtcctc
     1021 tttcgagagg gccttggcgt ccttggcggc acggtcctgc tggtggaacg acttgtactc
     1081 gacggccgtc tccacgcggc ggacgtcgcc gcgggcggag agccggctca acgcccacag
     1141 cggaatctgg gcgcggacgg tcttgccctc agtggacacc gagcggatgg tggagcccgc
     1201 gctgcggatc gcggcgacta actcgtcggt gaccttgtgg gcgcggatgt ccaccagaac
     1261 ggtgtttccg ctttggacct tcaccccggt ctggagttcc gggagcttgt tgaacgtcgt
     1321 cgagttggac cggcggcgct gttccacgat cagcgcgctg tccactttgg actcggcggg
     1381 cgtgacggac ttcttgatgg cctggagcgc ggagatctgg gcggcggtct tgtcctccgg
     1441 gctcttggcg gcccgagccg ggtcggcgga gaccggcgtg accgggccga gcagcgtgat
     1501 cagaactgcg gcaccggctg tgatcaggga gtttcttcgg gatcggcggt tcggtgagcg
     1561 cattggcgtc ccccaacgtc aagcgtgccc ccgacgcacg cggccaacgg tcggatgtct
     1621 ccgaccgagg gctcacaacg tattgtgcgc ggacgagtac cgtctgccac cgttcggcct
     1681 acttcccaca gggcaagaac catcacagtt cacagtacga acgcgtctgt ccacagctga
     1741 ccggtgcgtc cggacagggc gtcgagcagc gcggcggcct ggttgtcggt cagcgaggcg
     1801 acgaagtcga ccaccgcccg gccgcgcgcg agcgcccgga cggcgtccgg tccggacggt
     1861 gtgtcccccg tcgctccgac cagggacgac gggtcggtgc gcgccagcgc ggtgtactcg
     1921 gaggtggcga gttcgatcag gtcgtgcagc cggcgcggca gccggtcggc ctcgtgccgg
     1981 tcggtcgccc actgctccag cgcctcgacc aacgccgtca gcagccgggc ctgcccacgc
     2041 tggtgcagcg cgaggtcggg ccgaagcaac acgaaccttc ggtgcacgaa cttgagcacc
     2101 tgcacctcgt gccactgctg gacggccagc accacgtgcc cggacctggt gctcggctcg
     2161 tccagcacac cgaccgcgtc cacgagtcgc cgcgtccacc gcgcggagaa cgccgcgacc
     2221 gcctgttcgg cttccaccga cccgtcgaac ggcaccgcga gcagcccacc gacaagctcg
     2281 gtccgcacca tcgccacggc ttgggcgaac gcgtcgtcgt ccaccgccca cgagtccttc
     2341 aggtgcagtc ggcggcgcag ggcctccagc gaacgacccg gttgacgttc ctgcgcggcc
     2401 aggtcggcgg cgctgatgcc ggcgaggtcc acggcgtggt cgagccacgt gttcagttcg
     2461 gtcgacacgg tcgcgtgctg caacaccccg acccggtaga agtcctccag atcgtggatg
     2521 gcgtaggcga tgtcgtccgc agtgtccatc accgacgctt ccaccgtctg ctgccacggc
     2581 tcgacgcgac ccgcgtagaa cgcgcgggcc tgggtcaggt cgtcgagttc ggtcacgtag
     2641 gcggagaact tggccgcgcc cgtccccggc gcgtccggcg gctcggccgc gccgcgcggc
     2701 ggaacccgga ggtccttcgg gtgcggtttc gggtaggaca gtcgggtcca cgggtacttg
     2761 agcatcgccg cccggaccgc gaccgtcagg tcgagcccga ccgcggcggg acctcgcacg
     2821 tcggtcgtgg tgacgatccg gaacgactgg gcattgccct cgaacccgtc ggacagcccg
     2881 aaccggtggc gggccaggcg gtcgagcacc tgttcgccga ggtgcccgaa cggcgggtgg
     2941 cccaggtcgt gcgcgagggc cgcggcttcg accacgtccg ggtcgcaacc accgagcttg
     3001 tcgagcactc cgacgagttc gggtcgcgca ccgagccgtt ccgcgatcgc ccgtgcggct
     3061 tgcgccacct tgaggctgtg ggtgagccgg ttgtgcacca gcaggccgga gccggtggaa
     3121 ctgaccacct gcgtgacgcc gccgaggcgt gcgaagaacg gggaactcgc cacccggtcc
     3181 cggtccaccc ggaacggact ggtcgccagg tcggactgga gcggagtcga ggcgtccatg
     3241 cccgacctgc ggagtgctct ggggtcggcg tgctcgcggt gcatggcaag aaaatagtcc
     3301 gtgcggccgc cggaagcagc accggaacgt gaaaaagcct tcaggggcac ccgtcacggg
     3361 tgcccctgaa ggcgaaagaa tgttcggcgg cgtcctactc tcccacaccc tcacgagtgc
     3421 agtaccatcg gcgctggaag gcttaactac cgggttcgga atgggaccgg gtgttccccc
     3481 accgctatga ccaccgaaac actatgaaat taccaacccg taggcacccc aaccccgaga
     3541 cccaaatggc ctgggaccgt ggtggtccgg ttcggttctt tcagaaccgc acagtggatg
     3601 cgtagcatgt ttgtgagcaa gtcctcggcc tattagtacc ggtcaactcc agccgttacc
     3661 ggccttccat ctccggccta tcaacccaat ggtctcttgg gggccttacc ccacgaaggg
     3721 tgggatacct catctaggaa caggcttccc gcttagatgc tttcagcggt tatcccttcc
     3781 gaacgtagcc aaccagcaat gcccttggca ggacaactgg cacaccagag gtccgtccgt
     3841 cccggtcctc tcgtactagg gacagccttc cgcaagtatc ctacgcgcgc ggcggatagg
     3901 gaccgaactg tctcacgacg ttctaaaccc agctcgcgta ccgctttaat gggcgaacag
     3961 cccaaccctt gggacctact ccagccccag gatgcgacga gccgacatcg aggtgccaaa
     4021 ccatgccgtc gatatggact cttgggcaag atcagcctgt tatccccggg gtacctttta
     4081 tccgttgagc gaccacgctt ccacaagcca tggccggatc actagttccg actttcgtcc
     4141 ctgctcgacc tgtcggtctc acagtcaagc ccccttgtgc acttgcactc gacacctgat
     4201 tgccaaccag gctgagggaa cctttgagcg cctccgttac cctttgggag gcaaccgccc
     4261 cagttaaact acccaccagg cactgtccct gatccggatc acggaccgag gttagacatc
     4321 cagtacgacc agagtggtat ttcaacgacg actccacaac cactggcgtg gccgcttcac
     4381 agtctcccac ctatcctaca caagccgaac cgaacaccaa taccaagcta tagtaaaggt
     4441 cccggggtct ttccgtcctg ccgcgcgtaa cgagcatctt tactcgtagt gcaatttcgc
     4501 cgggcctgtg gttgagacag tcgagaagtc gttacgccat tcgtgcaggt cggaacttac
     4561 ccgacaagga atttcgctac cttaggatgg ttatagttac caccgccgtt tactggcgct
     4621 taagttctca gcctcgcccc gaagagctaa ccggtcccct taacgttcca gcaccgggca
     4681 ggcgtcagtc cgtatacatc gtcttgcgac ttcgcacgga cctgtgtttt tagtaaacag
     4741 tcgcttctcg ctggtctctg cggccgaaaa atcctagccc gcaaggggct tcaaatccct
     4801 cggcccccct tctcccgaag ttacgggggc attttgccga gttccttaac cacagttcgc
     4861 ccgatcgcct cggtattctc tacctgacca cctgtgtcgg tttggggtac gggccgcgtg
     4921 aacactcact agaggctttt ctcgacagca tgggatcacc ctacttcgcc tcaatcggct
     4981 atgcatcacg tctcagcctt gaatgcagca cggatttgcc tatgctgcgg cctacacgct
     5041 tacaccagta ctaccactca ctggcggagc taccctcctg cgtcacccca tcgcttgact
     5101 actacaagtt caggtcccgc gctccacatc gcccctcatc cgaagaatca gagcgggctt
     5161 cgggcggtta gtatcacaag gttcgccatg ggcgcgttca cacgggtacg ggaatatcaa
     5221 cccgttgtcc atcgactacg cctgtcggcc tcgccttagg tcccgactta ccctgggcgg
     5281 attagcctgg cccaggaacc cttggtcatc cggcggcaga gtttctcact ctgctttcgc
     5341 tactcatgcc tgcattctca ctcgtccagc ctccacacct ggatcactcc ggcgcttcga
     5401 tggctgaacg acgctcccct acccatccag acanaatctg aatgacacgg cttcggcggt
     5461 gtgcttaagc cccgctacat tgtcggcgca ggaccacttg accagtgagc tattacgcac
     5521 tctttaaagg gtggctgctt ctaagccaac ctcctggttg tctgagcgac cccacatcct
     5581 ttcccactta gcacacactt aggggcctta gccggcgttc tgggctgttt ccctctcgac
     5641 tacgaagctt atcccccgca gtctcactgc cgcgctctca cgtaccggca ttcggagttt
     5701 ggttgatttc ggtaagcttg tgggccccct agaccatcca gtgctctacc tccggcacga
     5761 aacacacgac gctgcaccta aatgcatttc ggggagaacc agctatcacg gagtttgatt
     5821 ggcctttcac ccctaaccac agctcatccc ccaggttttc aaccctggtg ggttcgggcc
     5881 tccacgcagt cttacccacg cttcaccctg gccatggcta gatcactccg cttcgggtct
     5941 agaccacgcg actcaaacgc cctattcgga ctcgctttcg ctacggctac cccacacggg
     6001 ttaacctcgc cacgcagcac taactcgcag gctcattctt caaaaggcac gccgtcaccc
     6061 cgaaaggctc cgacggattg taggcacacg gtttcaggta ctatttcact cccctcccgg
     6121 ggtacttttc acctttccct cacggtacta gtccgctatc ggtcaccagg gagtattcag
     6181 gcttagcggg tggtcccgcc agattcacag cgaatttcac gagtacgctg ctacttggga
     6241 acactacaaa gagacaccgg gttttcgcgt acgggactct caccctctac ggccacgctt
     6301 tccagacgcg ttccgctaac cacagtgttt tctcactctt tgccagtccg gcagaactgg
     6361 ccagtaggtc ccacgacccc gcacacgcaa cccctgccgg gtatcacacg aatacggttt
     6421 agcctcttcc gctttcgctc gccactactc acggaatcac ggttgttttc tcttcctgcg
     6481 ggtactgaga tgtttcactt ccccgcgttc cctccacacg ccctatgtgt tcaggcgcgg
     6541 gtgaccccac atgactgggg ccgggtttcc ccattcggaa atccttggat ctcagctcgg
     6601 ttgacaactc cccaaggctt atcgcagtct cctacgtcct tcatcggctc ctggtgccaa
     6661 ggcatccacc gtatgccctt aataacttgc cacaaagatg ctcgcatcca ctgtgcagtt
     6721 ctcaaagaac aaccagacac catcccacac agcccacgcc gacccgactc aacaccgggc
     6781 ggttcgcgga cggagaccgt cctgtcgttt ctcgccgaag aaaacacgaa acacgtgttc
     6841 cctcaggacc caacagcgta ccgaacagaa acccttgacc ctcgacagac ccttccacgc
     6901 ccccggaggg acagtactga ctccatcgac aacccgaagc tctgcactag ccagcatcca
     6961 catctgtgag ccccaccctg cgatcatccg ccgcaggcgt ggtctccacc acgatccgaa
     7021 gaccgaggcg agaggtgctc cttagaaagg aggtgatcca gccgcacctt ccggtacggc
     7081 taccttgtta cgacttcgtc ccaatcgcca gtcccacctt cgaccgctcc cccccttacg
     7141 ggttgggcca cgggcttcgg gtgttaccga ctttcgtgac gtgacgggcg gtgtgtacaa
     7201 ggcccgggaa cgtattcacc gcagcgttgc tgatctgcga ttactagcga ctccgacttc
     7261 acggggtcga gttgcagacc ccgatccgaa ctgagaccgg ctttgtggga ttcgctccac
     7321 ctcacggctt agcagccctc tgtaccggcc attgtagcat gtgtgaagcc ctggacataa
     7381 ggggcatgat gacttgacgt catccccacc ttcctccgag ttgaccccgg cagtctccca
     7441 tgagtccccg ccataacgcg ctggcaacat ggaacgaggg ttgcgctcgt tgcgggactt
     7501 aacccaacat ctcacgacac gagctgacga cagccatgca ccacctgtac accagtccga
     7561 agaggcctac atctctgcag gtttccggtg catgtcaagc ccaggtaagg ttcttcgcgt
     7621 tgcatcgaat taatccacat gctccgccgc ttgtgcgggc ccccgtcaat tcctttgagt
     7681 tttagccttg cggccgtact ccccaggcgg ggtgcttaat gcgttagctg cggcacggag
     7741 gacgtggaag ccccccacac ctagcaccca ccgtttacgg cgtggactac cagggtatct
     7801 aatcctgttc gctccccacg ctttcgctcc tcagcgtcag tatcggccca gagacccgcc
     7861 ttcgccaccg gtgttcctcc tgatatctgc gcatttcacc gctacaccag gaattccagt
     7921 ctcccctgcc gaactcaagt ctgcccgtat cgaccgcagg ctccacgtta agcgtgaagt
     7981 tttcacggcc gacgcaacaa accgcctacg agctctttac gcccaataat tccggacaac
     8041 gctcgcaccc tacgtattac cgcggctgct ggcacgtagt tagccggtgc ttcttctgca
     8101 ggtaccgtca ctcacgcttc gtccctgctg aaagaggttt acaacccgaa ggccgtcatc
     8161 cctcacgcgg cgtcgctgca tcaggctttc gcccattgtg caatattccc cactgctgcc
     8221 tcccgtagga gtctgggccg tgtctcagtc ccagtgtggc cggtcaccct ctcaggccgg
     8281 ctacccgtcg tcgccttggt aggccatcac cccaccaaca agctgatagg ccgcgggtcc
     8341 atcccatacc gccggaactt tccaccccac aagatgcccc atggggtcgt atccggtatt
     8401 agacctagtt tcccaggctt atcccggagt acagggcagg ttacccacgt gttactcacc
     8461 cgttcgccgc tcgtgtaccc cgaagggcct taccgctcga cttgcatgtg ttaagcacgc
     8521 cgccagcgtt cgtcctgagc caggatcaaa ctctccaata aggattgtgt ttgatcgctc
     8581 ggacaacact gactcgcaga ccgcaaaacg gcccactcca tcagttgtcc agtcaatctc
     8641 aaaggaaacc tcttgacgag gttcataaat ttactggcta ttcggcacgc tgttgagttc
     8701 tcaaagaaca cgcgctcacc atcttgaacc gcgttctacc gcagctcatt ccggggctgg
     8761 tgtttccgtt tgtgttgctg gaagcttagc tcgttcgttt tcgcggtgtc aaatcggccg
     8821 gtttcggctt ctcggctccg cgtcaaactc gcttcgcatt cagtttgctt gtctccggcg
     8881 ctggcgttcc ggtgtttccc ggcccgttcc gcgctggcag agagaaactt acacgagcac
     8941 cccgggatag tgaaatcggg gggtcgacca cgacatttgc ccagctagac gtggtgcgcg
     9001 gggccgggac ggaggatgct gtccgggtgc tgctctcccc tcgactccgc ccgtggggca
     9061 ggtacggcat ccacctcgcg gtggtcgccg cttgctacta cgcgggtgca cgcctgggcc
     9121 tgctccaggc gttggtcaac gaccaggtga ctccgctgtg gccaccgacc ggcgtggcgc
     9181 tgttggcgct gatgctcggc ggggtccgga tgtggccggg gatcgccgtg gccgcgttcg
     9241 tcgtgaacgc gacgctgggc gacagcagct cggcgttcct gatcagcgtc ggcaacacgc
     9301 tgggcccggt ggtcgccttc ctcctgctca agcactccgg cttccggctg gagatcgacc
     9361 gcgcgcggga cgcgctgacc ttcgtgttcc tgggcgcgtt cgtggggatg gcggtcagcg
     9421 ccacgatcgg caccggcgct ctgctgttgt cgggctcggt gggctggccg gacttctggg
     9481 cgacctggtc ggtgtggtgg acgggcgacg cgatgggcgt gctgatcctg gtccccctgg
     9541 tgttggcgct gcgcgggctg cggttccccg ttcgttccgc gcgtgcgtgg gaggccgcgg
     9601 cgctgttgac gtcgacgacc ggcgtgatgc tgatcgccgc gagcagtccg ctgcgcttgt
     9661 tgtacttggt gttcccgttc gccatctggg gcgcgctgcg gtttcagcac ctgggcgcgg
     9721 ccccgtgcgc gttgatcgcc accgtgctcg cggcgcgtgg ggccgcagcg gggatcgggc
     9781 cgttcgcgaa cctggacctg ttgcagcgga tggtgacctt gcaggcgttc aacgggacgg
     9841 tggcgttgac gacgctggtg ctgagcgcgg tgatctccga gcggaacgcg gcgcggcggg
     9901 cgatcgagcg gacgtgcgcg cagctcacgg acgtggtgga ggcgtaccgc ccgttgttgt
     9961 tgggcaacgg cgtgcggccg gaaccgccgg acggtcgcta gtggacgtgc tgatcgtcgg
    10021 tggagggccg gcgggccgcg cgctggcgtc ggcgtgttcc gcacgtggtc tcgtcacgtc
    10081 gttggtcgat ccgcacccgg gacgtccgtg gcgtgcgacc tacgcggcgt gggcggacga
    10141 gttgccggtg gacgcgccgg tcgcggtgtc gacgtcgaag gcgcgggtgt tcgcgacttc
    10201 ggagcaccgg atcgcgcgcg ggtacgcggt gttggacaac gagcggttgc gacggttgcc
    10261 cgacgacgtg cgggtggtgc ggggcctggt ggccgagcgg ggtcggcggc acgtggtgtt
    10321 gcgtgacggg cgtgtcctgc gggcgggcct ggtggtggac gcgaccggcg cgtcgggccg
    10381 ggtggcgcag cacgcggtgg gtgtggtggt ggctgccgag caggcgttgc cattcgtggt
    10441 ggacgacgag gcgctggtca tggattggcg cagaccaccg gacgcgggct cgccggaccc
    10501 gacgttcctg tacgcgatcc cgatgccggg cggcggtgtg ttgttggaag agacgtcgct
    10561 ggcgcgtggc ccggggctgc cgttgccgga gctgcggttg aggctgcgcg cacgccttgc
    10621 ggcgcacggg gtcgcgctcc cccacgacga ggaacgggtg cggataccgt tggcggcacg
    10681 gcctcggcgc ggcgcgttcg gggcggcggc ggggctggtg cacccggcga ccgggtacag
    10741 cgtggcggag gcgttggcgc tcgcgccgga ggtggcgcgg gcgatcgcgg acggggtgcc
    10801 ggtggaccgg gtggtgtggc cggcgcgggc cagggcggtg cacgcgctgc gccggtacgg
    10861 cctggccgcg ctgctggtga tgcggcccga ccaggtgccg gaatttttcg acctgttctt
    10921 ccatttgccc gagaataagc aacgaatgta tctcagtggg cgctccgacc tgcacggaac
    10981 ggtttcggcg atgtccgctc tgttccgaac ggcggactgg cggatgcgcg ctcgattggc
    11041 attcaccgtg cagccggcca aggctgtgag aactcctggt taacggtctg ggcaagacaa
    11101 gatcgaccgg gcaggatctg gtgacgtgcc cgctttgctg gatgacgttc gcttcgcctt
    11161 ccagccgctg ttcaacctca acaccggagg ggtcgtcgcg gtcgaggcac tggcccgccc
    11221 gcacgacggc agcgtgcagg atctactccg catggcgttc cgtgcggggt atttggcgaa
    11281 caccgatgtg gccctcgcct gccgtgcgat ccgcagcgcg gctgatcacg acttcaccct
    11341 gccgctgcac gtgaacctgc tcgcgatgac catcgcggac aagtccgagc acatggctcc
    11401 gctgtacgcg gcgctgcgcg acgcaggtcg tcccaccgcc aacctggtga tcgaggtcgg
    11461 cacgccgtac tcgcgcgcgc cgcgccaccg actcgtcaag ggtctggacc ggctgcgcca
    11521 ggacgggttc aagatcggcc tggacggggt cggcgagggc gacgccccgc tgtcgctgct
    11581 ggccgaggtg cagcccgagg tggtgaagct ggaccgcgag gtggtccagg aactggtcga
    11641 cgacccggcg cggttcgcgc tggtgcaggg cttgcagcac ctgtgcgagg cgaccggttc
    11701 gctgatcgtc gccgagggcg tggagaccga gccgcagctc gcggcgctgc gccggctggg
    11761 ggtgcggctg gcgcagggca acctgctggc cgccgcgcaa cgccggccga agatcaacgc
    11821 gaccatctcg accgtgctca gcgaggtcaa cgaccccgag gcggcgacca agacgaccac
    11881 caagccgctg cgccgcaagc ccggtccgaa ggtgaccgac ttcctgcacc cggcgacgac
    11941 cctgcccgag tccgcgacct cggaggacgt ccgggacgtg ctggccacgc agcccaccgt
    12001 gaccggggtc gtgctggtgg acgacgacgg ccgcccgacg tggacggtgg accgcaaccg
    12061 gttcctgctc gcggtcaccg ggccgttcgg gcacgcgctg cacgccaagc gggaggcggc
    12121 gcggctggcc gacccgcccc gggtgatcgg ggccgggtcc acggcgatgg agatgctcga
    12181 cgtggtcgcg cacaccaacc gcgagcgcac caacgacgac ctggtggtcg tggacgacga
    12241 cgaccggtgc gtgggtgtcg tgcgggtggc cgacgtggtg cgcggcatcg cggagatgaa
    12301 ggtcgagcag gccgcggcgc tgagcccgct gacccggctg cccggcagcg actcgatcgc
    12361 gcgcgaggtc gaccggcgga tcctgtccgg cgagatcttc gccgtggggt ggctcgacgt
    12421 cgacgcgttc aagcgggtga acgactcggt ggggttcgcc gccggtgatg acctgatcag
    12481 ggcgttaggg cgtaagctga ccgaaggtgc gacggcgttc cccgggattc aggtggggca
    12541 cgtcggtggc gacgacttcc tggtcgtcgc ggggctgaac gaggtcgtgc cttacgcggc
    12601 gggtgtattg gatacgccgt ttgacgcaga gggacacgcg gtaaccctgt cgctggcgac
    12661 gctggtgtgc gcggccgggt cggtggggtc ctaccgggag gtgtcccgcc tgctggcgcc
    12721 gttgaaggag cacgcgaagt cgttgcgcgg caacagttgg gtgctgggcc gtccgggcag
    12781 cgaccacgtg gacgtgctgc gcggcggcgc gcatttggcg gtcagctagc cggaccggaa
    12841 gttcaccgca acgatgcatg tgcacccgcg ctgatcactc atagcatcag gatgactacc
    12901 caccgcaggg aggcccctgg tgagcgaagt cgacgtcagc gcgctgccgc gtccgcgaac
    12961 cgagttcgac cccgcgttgt cagtcggcgt ggaagaggag ttcctgctgg tggacgcggt
    13021 caccggggct ctgtcgccgg tggcgggcga agtgctgggt gacgcggacg gcgtgctgga
    13081 cctccagtcc gagatgaccc gctaccaggt ggagagcgcg accgcggtgt gctggtcgat
    13141 ggacgaggtg cgcgagcagc tcgtgctgtc ccggcgcgcc ctcggcgacc tggccaaggg
    13201 gcacgacgcg cggatcgtgg ccaccggcac cccggtgctg ggcggcagcc ggccgccgcc
    13261 gttgaccgac cggcagcggt accgggacat cgagcaccgg tacgggtcgc tgatcgacgc
    13321 gctgaccatc tgcgggtgcc acgtgcacat cgggatcccg gacgaggaga ccggcgtgct
    13381 gatctccaac cacctgcggc agtggctgcc ggtgctgctg gcgatcagcg cgaactcgcc
    13441 gttctcggag gggcgtgaca cggggtacgc gagctggcgg tacctgtcgt ggagcccgtg
    13501 gccgtcggcc ggcgcgccgc cgtggttcgc ctccgtggag gactaccacc tgggcacgcg
    13561 cacgttgcgg acgtccgggg cggcgatgga caccgggatg atctactggg acgtgcggct
    13621 gtcggccagt cacccgaccg tggagctgcg ggtgtgcgac gtggcggcga ccgtcgagga
    13681 ggcggtgctg atcgcggcga tcgcgcgggc catcgcggtg gtcgcggtgt ccggggcggc
    13741 ggcgttcccg gtgtcggacc tggcgttgcg ggcggcgttg tggcgtgccg cgcgggacgg
    13801 ggtcgagggg gcgggggtcg agccgcacac cgggcggttg gtggcggcgg cggacctggt
    13861 gcggacgttg gtggagtgga ttcggccggc gttgcgggcg tgcggggacg aggcgttggt
    13921 ggacgacggg gtgggacggc tgttgctgga cgggtgcggg gcgacccgac agcgccgggc
    13981 gttcactcgt cggggtgaac ttgccgacgt ggtggcgatg ttggtggcgc agacctgact
    14041 ccgccgcttg atcttagact ccgggtcgtg gacgacgtcg tgctcggatc ggtgacctgc
    14101 ccgtccgggc acctcgtgct ggtggacggc ggttacctgc ggttgtggtc cgcgcagcgg
    14161 tcgccggacg agtccggcgg tgacgcggcg gtcgacttcg aggtcgtcgg gtctgacgct
    14221 gacgccgcgg cgcggtcctt cgaccaccag gccgggcgca ggctgtacga catccccgag
    14281 cacgcggtgg tgccgttcac cgcgaagttc gacgagcact gccgggcggg tgggttcggt
    14341 gcttcgctgc ggccgttccc ccgtcgggtg ccgcaccgcg accgggtgcg gcacgcgctc
    14401 gaggcgggtg atccggagtt cctgatcacc ggagtgccgg tcgtgccgat cggtggtgtg
    14461 ccgaccggtc gggcgctgcg ggtcgtggcc acgcgcggcc agtgggggtg ggcccggatt
    14521 cggatcgagc tcggcggcgg gacggtggtg gagcggcgcc cgttggggac gatcagggtc
    14581 gaccacgccc ggttcgcctt cgccgacgcg gacgcgctcg ggtcgtgggt gcacgacgat
    14641 ccgctcgacg ggctggccga cgtcgtgttc tggggtgggg acgaggacgc gatcgccgag
    14701 gagttcgagg cccggcgcac gaggacgccg ggcgacgaca ccttcggctg ggtcgatctc
    14761 ccggtccggg aggcgtaccg gctggcggtg gccttggaag agcggcgcgg cgtcgcgccg
    14821 gaacgcaggt tcgccgtcga cttccggccg cactcgcacc actggcaggc gatgcgggcc
    14881 gtccgggcga gcgagcacga ggccgcgacc ctggcggtgg gcggtgccga cgtgatgctg
    14941 gcgatgacgt cggtcggcga cggcttcttc cccgcccacc tcgacgtgga cgcggcgggc
    15001 gcgccggtcg ccgtcgagat cgacctctcg tagtacgggt cggggcagca cgacggccgc
    15061 cccgatgtcg tcgctacctc ttgtattcgg cgtggaacgc gtggaacgcg ggcgacgttg
    15121 gccacgaagg cgatcgactt gccgtccgcg atgtggagca gggtgagcgg gaggcccagc
    15181 gcggtgacgt tgccggcgaa gcgagcgctc cgcgcgttcc tcggcgaggg cgtcgacctt
    15241 gggcgccgcg acgaggggtg cggcggacag cagcgcgtgg gcgtactccg gtcggatcgt
    15301 agaggctgat catcgcttcg acgtcggcgg cgttcaacac ctcacccgtt cgctgcacgt
    15361 ggacgcggtg cagttcacct gcggggacgg gtccgtggag ttgctgttca caccggaggc
    15421 gttgcggttg atgaaagcgg gtgggtgatc ggggccggga acgccgacag cggccgccgt
    15481 ggtgggcgac cgctgtcgag ggtggtgcga aaagccggag agctagaccg tgaagccgag
    15541 ggcgcggagt tgttcgcggc cgtcgtcggt gatcttctcg gggccccacg ggggcatcca
    15601 gacccagttg atgcggaagt cgttgacgat tccgccgccg ggaccgccgg tcagggcggt
    15661 gcgggtctgg tcttcgatga cgtcggtcag cgggcacgcc gccgaggtca gggtcatgtc
    15721 gatcagcgcg acgttgtcgt cgtccacgcg gatgtcgtag accaggccga ggtcgaccac
    15781 gttgatgccc aactccgggt cgaccacgtc gcgcatggcc tcttcgaggt cgtccaggct
    15841 gggcaggtcg gccttcggcg cgggcggttc gggcatgccc tccacgccgc ggaccacctc
    15901 gtcggtgtgt tccgcggtcg agccttctgg ggtggtcatg ctgttgctcc ttcgctgcgg
    15961 gccaccgcgt ccttgaaagc catccaaccg agcagcgcgc acttcaccct ggccgggtac
    16021 ttggccacgc cggcgaacgc gatgccgtct tccagcacgt cctcatcggg ctcgaccttg
    16081 ccgcgaccct gcatgagctc gacgaacgcg tccagcttct ggaacgcctc ccccaccggc
    16141 ctgccgacca ccaggtcggt cagcaccgag gtcgacgcct ggctgatgga gcagccctgg
    16201 ccgtcgtagg agacgtccgc gaccttgtcg ccgtccagct tcacccggag cgtgacctcg
    16261 tcaccgcagg tcgggttgat ctggtgggac tcggcgtcga acgggtcgcg caggccgcgc
    16321 ccgtgcgggt tcttgtagtg gtccaggatg atctcctggt acatctgctg aagctgcacc
    16381 tacgccacca ccccgaagaa cttctgggct tcgcgcacgc cctccaccag ggcgcgcacc
    16441 tcgtccagcg tgttgtacag gtagaaactc gcgcgcacgg tcgcggcggc gccgagccgc
    16501 cggtgcagcg gccacgcgca gtggtggccg acgcggaccg cgatgccgag gctgtccagg
    16561 acctggccga cgtcgtgggc gtggatgccc tcgaccacga acgacacggc accgccgcgg
    16621 tcctgcgtgt cgagcgggcc cacgatccgg acgccgggga tctccgccag gccgcgcagg
    16681 gccgcctcgg tgagcacgtg ctcgtgcgcg gcgaccctgt ccatgccgat ctcgctcagg
    16741 tagtccacgg ccgcgccgag cgccaccgcc tgcgaggtca tcggcacgcc ggcctcgaag
    16801 cgctgcggcg gcggggcgaa cgtggagctc gccatctgca ccatctcgat catcgacccg
    16861 ccggtgagga acggcggcaa ggtctccagc agctcacggc gtccgtagag gacaccgacg
    16921 ccggacgggc cgagcatctt gtggccggag aacaccgcga agtccacgcc cagcgcccgg
    16981 aagtcgaccg ggccgtgcgg caccgactgg cacgcgtcca gcacggtgag cgcgccgacc
    17041 gcccgcgccc tgtccacgat ggaccggacc gggttgacgg tgccgagcac gttggactgg
    17101 tgggtgagcg cgacgacctt ggtccgcccg gtgatcagcg agtccacgtc ggacaggtcg
    17161 agccggccct cgtcggtcac gccgaaccag cgcagggtcg ccccggtccg ctgcgccagc
    17221 tgctgccacg gcacaaggtt cgcgtggtgc tccatctcgg tcacgacgat ctcgtcgccg
    17281 gggccgatcc ggaaccgctc ggcctcgggg ccggcgaccg aggcgttgcc catcgcgtac
    17341 gcgaccaggt tcacgccctc ggtggcgttc ttggtgaaca cgatctcgcc gaagtcgacg
    17401 cccacgaacg cggcgatctt cgcccgcgcg ccctcgtagg cgtcggtcgc ctcctcggcg
    17461 agctggtgcg cgccgcggtg cacggcggcg ttcgcggtct ccaggaacgc gcgctcggcg
    17521 tcgaggacct gcctcggccg ttgcgaggtg gcgccggagt ccaggtagac cagccgcttg
    17581 ccttcccgca cggtgcggcc caggatcggg aagtccgcgc gcacggtagc gacgtccagt
    17641 ggagcagcgg tggtggtcac agctccgacg cctcctctcg aactgttgaa cacacgacta
    17701 ggacaacgtc agccgacctt ggcggcttcc tgcacacccg cgtacttcac gtaaccgtgc
    17761 tcttcgagct ggtcggccag ctcgcggccg ccggactcga cgatccggcc gttcgcgaac
    17821 acgtgcacga agtcgggctg gatgtacttg aggatccggg tgtagtgggt gatcagcatg
    17881 acccccgcct caccggactc cttgaacttg ttgacgccct cggagaccac gcgcagcgcg
    17941 tcgacgtcga ggcccgagtc ggtctcgtcc aggatcgcga tcttcggctt gagcagcccg
    18001 agctgcagga tctcgtggcg cttcttctcg ccgccggaga agccctcgtt gaccgagcgc
    18061 tcggcgaagg ccgggtcgat gtccaggtcg gccatcgcgc ccttgacctc cttcacccag
    18121 tgccgcaggg ccggggcctc gccgcgcacg gcggtggcgg cggtgcgcag gaagttcgac
    18181 atcgagacgc cggggacctc gaccgggtac tgcatggcga ggaacaggcc cgcgcgggcc
    18241 cgctcgtcca cgctcatctc cagcacgtcc tcgccgtcga gggtgacggt gccggaggtg
    18301 atccggtact tggggtgccc ggcgatggcg taggacaggg tggacttgcc cgacccgttc
    18361 ggacccatga tcgcgtgcgt ctcgccggcc ttgatggtca ggtcgacgcc cttgaggatc
    18421 tccttggacg tctcgtcggt ggtgaccgag acgtgcaggt ccttgatctc cagagtggcc
    18481 atgtggtgct cagttctcct ggtgtgccgc ccggggtggg agcggctcgg aagtcagttc
    18541 gtggtggcgt tcaaggtggc ggtgacgtcc acgtagacgt cgccgtcacg gatgtcgacg
    18601 gcgaagacgt cgaccggttc cgtcgcgggc ggggacgagg ggcggccggt gcgcaggtcg
    18661 aagcacgacc cgtgcagcca gcactcgacg cccttgcggg tcacgtcgcc ctcggacagc
    18721 gcgacctccg cgtgcgagca gaggtcgcgc agcgcgtgga cggacccgcc gtcgcggacg
    18781 agcaggaccg gggtgtactc gtcgccgacc tcgaacgcga ccggcttgcg gtcgtccagg
    18841 tcggtcagcg agcacacccg gatcacacgc ccaccgcttc cagctccgcc tcgatcgcgg
    18901 cttccaggcg ctcgcgcacc tcggggacgg cgatcttgag caggatctcg tggaagaagc
    18961 cgcgcacgac cagccggcgg gcctgctcct ccgggatgcc ccgggcctgc aggtagaaca
    19021 gctgctcgtc gtcgaaccgg ccggtggcgc tggcgtggcc cgcgccctcg atctcgccgg
    19081 tctcgatctc caggttcggc accgagtcgg cgcgcgcgcc gtcggtgagc accaggttcc
    19141 ggttgagctc gaaggtctcg gtgccctcgg ccgccgcgcg gatcagcacg tcgccgatcc
    19201 acacggtgtg cgcgtcctcg ccctgcagcg cgcccttgta gaccacgttg ctgcggcagt
    19261 tggacaccgc gtggtcgatg aacgtgcggt gctccaggtg ctggccggcg tcggcgaagt
    19321 acaggcccag cagctcggcg tcgccgccgc gcccggtgta ggtgaccacc ggggtgagcc
    19381 ggaccaggtc gccgcccagg gtgatgacgg tgtgcttgaa cgtcgcgtcg cggcccagct
    19441 tcgcgtggtg cgcggagacg tgcacggcgt cgtcggccca gtcctggatc gccacgaccg
    19501 tcaggtgcgc gccgtcggcg acgacgaact ccacgttgtc ggcgtacgcg ccggacccgc
    19561 ggtggtcgat caccacgacg gcctcggcga actgctcggc ccggacctgg aggtggccgt
    19621 aggcgacctc gcccttgccc gcgccggtca ccgtgacggt ggtcggctcg accttggtgt
    19681 ccttgggcag ggtgatcacc gtggcctcgg cgaacgagtt ccacgcctgc gccgcgatcc
    19741 ggtccgccgg cgtgccggcg gtgcccaggc gctcgtcgcc ccgggcggcg gtctcgaccc
    19801 ggacgccctc ggccgccttg acctcgacgg tggcggtgcc cgtggcgggc acgccggtgt
    19861 gcaggccggc caggcgcttc atcggggtga agcgccagat ctcctcacgg ccgccgggca
    19921 cctcgaacgc gtccacgtcg aacgacgcga agtggtccgc gcgcgacgag atcggggcgc
    19981 ccgcgccgtg ggagtgggcc gtcaggccgt gctggtcttg agtggtgacg gccatgtcag
    20041 ccgacggccc cttccatctg cagctcgatc aggcggttca gctcgagggc gtactccatg
    20101 gggagctcgc gcgcgatggg ctcgacgaac ccgcgcacga tcatcgccat ggcctcgtcc
    20161 tcgttgaggc cgcgggacat caggtagaac agctggtcct cggacacctt cgagaccgtg
    20221 gcctcgtggc ccatcgacac gtcgtcctcg cggacgtcga cgtaggggta ggtgtcggag
    20281 cggctgatgt tgtcgaccag cagcgcgtcg cacttgaccg tggacttcga gtggtgcgcc
    20341 cgcttgttga cctgcacgag cccccggtag gaggtccggc cgccgccgcg cgccaccgac
    20401 ttcgacacga tcgtggacga cgtgtgcggc gccatgtgga ccatcttcgc gccggcgtcc
    20461 tggtgctggc cctcgcccgc gaacgcgatg gagagcacct cgcccttggc gtgctcgccc
    20521 atcaggaaca cggccgggta cttcatggtg accttggagc cgatgttgcc gtcgatccac
    20581 tccatggtcg cgccctcttc ggccttggcg cgcttggtga ccaggttgta gacgttgttc
    20641 gaccagttct ggatggtcgt gtagcggcag cggccgccct tcttcacgac gatctccacg
    20701 accgcggagt gcagcgagtc cgaggagtag atcggggcgg tgcagccctc gacgtagtgc
    20761 acgtacgcgc cctcgtcgac gatgatcagg gtgcgctcga actggcccat gttctcggtg
    20821 ttgatccgga agtaggcctg cagcgggatc tcgacgtgca cgcccttcgg cacgtagatg
    20881 aacgagccgc cggaccacac ggccgagttc agcgcggaga acttgttgtc acccgagggg
    20941 atgacggagc cgaagtactc cttgaagagc tccgggtgct ccttgaggcc ggtgtcggtg
    21001 tcgaggaaga tgacaccctg cttctccagc tcctcgttga tcttgtggta gaccacctcg
    21061 gactcgtact gggcggcgac acc
//
