LOCUS       NC_019673              26167 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Saccharothrix espanaensis DSM 44229, complete sequence.
ACCESSION   NC_019673
VERSION     NC_019673.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Saccharothrix espanaensis DSM 44229
  ORGANISM  Saccharothrix espanaensis DSM 44229
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Saccharothrix.
REFERENCE   1
  AUTHORS   Strobel,T., Al-Dilaimi,A., Blom,J., Gessner,A., Kalinowski,J.,
            Luzhetska,M., Puhler,A., Szczepanowski,R., Bechthold,A. and
            Ruckert,C.
  TITLE     Complete genome sequence of Saccharothrix espanaensis DSM 44229(T)
            and comparison to the other completely sequenced Pseudonocardiaceae
  JOURNAL   BMC Genomics 13, 465 (2012)
   PUBMED   22958348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9360653)
  AUTHORS   Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2012) IGS, CeBiTec, Bielefeld University,
            Universitaetsstr. 27, D-33335, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000328705.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:06:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,451
            Genes (coding)                    :: 8,313
            CDSs (with protein)               :: 8,313
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 43 of 138
            Pseudo Genes (incomplete)         :: 116 of 138
            Pseudo Genes (internal stop)      :: 7 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:45:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5672302
            Orig. end                         :: 5698469
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE804045.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26167
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26167
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26167
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16167]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16167
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(1092..2108)
                     /locus_tag="BN6_RS24555"
                     /old_locus_tag="BN6_50750"
     CDS             complement(1092..2108)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /function="Glycosyltransferase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102454.1"
                     /locus_tag="BN6_RS24555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50750"
                     /product="glycosyltransferase"
                     /protein_id="WP_015102454.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.6e-11,
                     bitscore: 40.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIAMVTSVESDIPVVDLSSALSGEGHEVVVHSARIAADDKGPGQ
                     RLQSFVTTLREQWSDSSPEVVHTHSWTAGLAALFAARPLGIPVVHTFHDAGRGPVERVN
                     VERAVCRSAVRVVATSGDELPALLRLGVERSKVSVVPYGVDRRRFAPEGPSALRGSTHR
                     IVTAAPDGLPHELVTALRALPEAELLVLDGTPAVDDLAEELGVADRVVRLAAADDDLPA
                     LFRSADIVVCGPWCERPSVLAMQAMACGVAVVSTMTTEGMADVVVNHVTGMIPSQRGTG
                     GLSRLLNGLLVDTARREAYAIAGTDRVSARYGIERVAGGIAEVYASAVHCGLDRAGS"
     gene            complement(2267..2923)
                     /locus_tag="BN6_RS24560"
                     /old_locus_tag="BN6_50770"
     CDS             complement(2267..2923)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102455.1"
                     /locus_tag="BN6_RS24560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50770"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_231904741.1"
                     /transl_table=11
                     /translation="MTVLRAVVGACAAVLGADAVGVLVVDPRGGVEVAAASDERARFVE
                     LLQAQLRQGPCLDGIAEDAVVAVGDLDGARGRWPEFAEAALREGYRAVYAFPMRLLGRA
                     VGGVNLLYTVPTRLSERVVRRGQGLADLAVLGLSQERGPRRVERLAERTVAALHDRAGV
                     SQAVGVLLAVSSGGPEDARAVLERYSVRTGVPVSEVARALTDGSLDPHAVVERVG"
     gene            complement(3051..3764)
                     /locus_tag="BN6_RS24565"
                     /old_locus_tag="BN6_50780"
     CDS             complement(3051..3764)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024583.5"
                     /locus_tag="BN6_RS24565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50780"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_015102456.1"
                     /transl_table=11
                     /translation="MDGRRHEELWRLVTTYAQDHPPASGWVSAVCAVALGRIDVDAAAI
                     TVRAAGRTQQLAAASDAWAASLEELQYTVGEGPGMSAFRDGEAVLVGDLNTEAGRWPGF
                     VHEAATADVRAAFAFPLRVGAIQVGTFALYRHRAGPLDAEGFGDAVALADLATTALLTD
                     SKDEKPVASWAREDVSSFYDDVNMAIGMLATLLQINLEDALLRLRAYAYSNQLPLTEVA
                     RQVLSRELRLDSAAE"
     gene            complement(3996..4325)
                     /locus_tag="BN6_RS24570"
                     /old_locus_tag="BN6_50790"
     CDS             complement(3996..4325)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102457.1"
                     /locus_tag="BN6_RS24570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50790"
                     /product="hypothetical protein"
                     /protein_id="WP_015102457.1"
                     /transl_table=11
                     /translation="MPSGSNAKRERQYEHIKDSAKERGESTKRAKEIAARTVNKNRAQA
                     GESKTASRTSTRDTSPQRRGGQRSGNRQGPQGPTRDQLYNEAKKKNIKGRSTMTKKELA
                     SALGR"
     gene            4500..6290
                     /locus_tag="BN6_RS24575"
                     /old_locus_tag="BN6_50800"
     CDS             4500..6290
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102458.1"
                     /locus_tag="BN6_RS24575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50800"
                     /product="thiamine pyrophosphate-requiring protein"
                     /protein_id="WP_015102458.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.8e-45, bitscore:
                     152.5, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.1e-29, bitscore:
                     100.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETVGDYVLARLRDWGVEQVFAYPGDGINGIVAAFGKADDNPRF
                     VQSRHEEMSAFEAVGYAKFSGKVGVCLATSGPGAIHLLNGLYDAKLDHVPVVAIVGQTA
                     RSAMGGSYQQEVDLQALFKDVASAYLVEVNVAEQLPNALDRAIRAAEAERAPTAIIIPS
                     DLQEEEYTPPKHAFKQVPSSPPSRVKSVLVPDQDEIARAAEVLDAGEKVAILIGQGARS
                     AAEEVVQVAELTGAGVAKALLGKDVLSDELPFVTGSIGLLGTRPSYELMRDCDTLLIVG
                     SNFPYSQFLPPYGQARAVQIDIDGKLIGMRYPTEVNLVGDAGATLRALLPLVRRKADRT
                     WREKIEGDVRDWWETMDRQAALDAKPVNPMRIVSELSARAPHDAIFTADSGSAANWYAR
                     HLRMRGDMRGSLSGTLATMGPGVPYAIGAKFAHPDRPVIALVGDGAMQMNGMAELITIA
                     RYRELWSDQRLVVCVLHNNDLNQVTWELRAMGGAPKFEQSQTLPDVDYAGFARSLGLAA
                     ITVDAPDQLGPAWDRALTASVPTVLDVHCDPEVPPIPPHATFDQFKSVTEAILKGDPAA
                     WHLMAQGIRTKAQELLPGKR"
     misc_feature    4530..4543
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.54"
                     /tool="antismash"
     gene            complement(6399..6758)
                     /locus_tag="BN6_RS24580"
                     /old_locus_tag="BN6_50810"
     CDS             complement(6399..6758)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS24580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_50810"
                     /product="hypothetical protein"
                     /protein_id="WP_015102459.1"
                     /transl_table=11
                     /translation="MTSPSPRRPARLLSAALLTATTTALVVLGAGQAQATVLSRGANQA
                     AADERCAAAYDGEADGNGVYADVVLADDRHFSVWDGNGSDGNWGPASCFDAQIARFRVC
                     EDHSGCADWFWWPKP"
     misc_feature    complement(6752..6768)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.41"
                     /tool="antismash"
     gene            6973..8421
                     /locus_tag="BN6_RS24585"
                     /old_locus_tag="BN6_50820"
     CDS             6973..8421
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012859.5"
                     /locus_tag="BN6_RS24585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50820"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_041313891.1"
                     /transl_table=11
                     /translation="MAEDTPPGSTDAPDPRTATDIAMFVELLRRLRTRAGNPGYKKTLE
                     RATRDEHGIPRISGSTLHRVLEGHQDLARMRDPDVFVRELVTALGANPRPWSEALDRLL
                     HPATPEPPVEPATDTTPVRRTRRGLLAVTAAVLLVAAGVVVWSTAGPHEPPAAPPTGPV
                     RLSISLAADPALSLAVDPTADPSVTHTILADDAAGTGWEMVAPYHAGPRSWQLRASGRL
                     LSCLEVLGAGYAEGTLVQQYGCNGRPHQHWTPEPQEDGTLRWINFHSEQCLTAAGTRPR
                     AGTELVQRECDPARAALQQWRVTTIDTPLPPTVPNSVVPGRPGPGPTDYPGGGKDHPCH
                     GVGPALDPRATAWAAQPSPVGGQDPGGGRVSMGPDTAGAVELMHATRTTDTGDHTFYWA
                     EGWIAFSPHLFTMSLQWTTAPGSGDWHTCTVPFTTEHGAHGRPATTALPRSPDGTGHLA
                     FRTCITYTPELEPREPMINCSGRH"
     gene            complement(8499..9968)
                     /gene="crtI"
                     /locus_tag="BN6_RS24590"
                     /old_locus_tag="BN6_50830"
     CDS             complement(8499..9968)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Phytoene dehydrogenase and related proteins"
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102461.1"
                     /locus_tag="BN6_RS24590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50830"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_015102461.1"
                     /transl_table=11
                     /translation="MTRRASPRPVVVVGAGLAGLSAALHLRGDGHEVVVVEQAAHCGGL
                     MGRLDVDGHRVDTGPTVLTMPELVDEALAAVGDRLADRVELLPLDPAYRAVFADGSAID
                     VHTDAAAMEHAVREFAGGADADGYRRLRAWLTRLYEVQRDRFIAANFDSPLDLVGRDLA
                     ALAGLGGFGNLTGAVSRFLRDPRLQRVFTFQALYAGVAPQDALAAYAVIAYMDTVAGVW
                     FPRGGMRQVPAAMEAAAVAAGIEVRRDTEALALERTGDRVTAVLVGGDRIPCGAVVLAT
                     GPGQTTRLLRGRPRRTLRWSPSAVVVHLSARRVVDGLAHHTISFGDAWETTFDEIISRG
                     RLMSDPSLLLTTPTRTDPSLAPPGRDLHYLLAPCPNLDRNPLRWDLRGSGYADDLVDTL
                     VRRGLIASADDVTRIALSTPDDWAAGGQAAGTPFSAAHTFGQTGPFRPRNLPFRRGNVV
                     LAGSGTTPGVGIPPVLISGRLAARRLRTPAD"
     gene            complement(10001..11086)
                     /locus_tag="BN6_RS24595"
                     /old_locus_tag="BN6_50840"
     CDS             complement(10001..11086)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Geranylgeranyl pyrophosphate synthase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102462.1"
                     /locus_tag="BN6_RS24595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50840"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_015102462.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-46, bitscore:
                     157.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLTAVGPTVDDDLPRRLGEELEGYLALRRDGGLAPELGDALADL
                     ALGGGKRLRPTFAWWGWRAAGGAAGGPEADALVRALVALELLQCCALIHDDVMDRSATR
                     RGRPTAHRVFAARHRRERWAGDATHYGDCAAILVGDLALAWADDALVRAGLPGSALTRA
                     WEPWQAMRTEMMAGQHLDLLGGATRSESVAAGLRVARLKTAAYTVERPLHLGAAVADAP
                     AAVIDALRAYGRDIGVAFQLRDDLLGSFGDARVTGKPVGEDLREGKRTPLMATALGLAR
                     TAGRADAVRALRDCLEGGATDHELAHVRALLHDLGAVAVIEERITALTTSGLRALDAAA
                     LVPAARDRLVALAEQATARTR"
     gene            11229..12155
                     /locus_tag="BN6_RS24600"
                     /old_locus_tag="BN6_50860"
     CDS             11229..12155
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /function="Phytoene/squalene synthetase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102463.1"
                     /locus_tag="BN6_RS24600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50860"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_015102463.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.5e-123,
                     bitscore: 409.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.1e-68,
                     bitscore: 230.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADRELDAAKITDPAMRAAYRRCRALNAEHGRTFYLATRLLPPD
                     RRPAVHALYGFARWVDDIVDEVDDGRTAAQRAAELTAVEGLLEQGLRTGASDNPVISAL
                     LDTSGRYGIPRAHFEDFMSSMRMDLTVTDYPTWDDLARYVHGSAAVIGLQVLPVLGTTV
                     PRAEAEPAAADLGVAFQLTNFLRDVGEDLDRGRVYLPADELAASGVDRDLLVWSRRTGR
                     ADQRVRDALAAQVARARRAYRAAEPGLRVLDPRSRPCVATAFRLYGRILDLVERADYDV
                     LSRRVAVSQGRRLVVALPALARAAFAH"
     gene            12278..13234
                     /locus_tag="BN6_RS24605"
                     /old_locus_tag="BN6_50850"
     CDS             12278..13234
                     /codon_start=1
                     /function="Phenylpropionate dioxygenase and related
                     ring-hydroxylating dioxygenases, large terminal subunit"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102464.1"
                     /locus_tag="BN6_RS24605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50850"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_015102464.1"
                     /transl_table=11
                     /translation="MPKLPLRLFRSRPWPEQEPTWRAAAPALIGSALARATARPSGNWF
                     TVCASREVPGDRPFGRTVAGREVVLWRGADGGLRAGPGACPHLGAPLRDGVVHRGEVVC
                     RWHGLALGEAKFGRWSPYPAHDDGVLAWVRLDDVGGEDPLPAPVLPARPPAGAIEAVTT
                     VIGRCEPEDVVANRLDPWHGAWFHPYSFANLRVVGTPTDDEDRFLVEVTFKLVGRVGVP
                     VVAEFTCPEPRTVVMRIVSGEGVGSVVETHATPLSPGPDGAPRTAVIEATVAHSSRRGF
                     ALTRPAAPLIRPVMRWAAARLWRDDLAYAERRYALRA"
     gene            complement(13265..14818)
                     /locus_tag="BN6_RS24610"
                     /old_locus_tag="BN6_50870"
     CDS             complement(13265..14818)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Uncharacterized conserved protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102465.1"
                     /locus_tag="BN6_RS24610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50870"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_015102465.1"
                     /sec_met_domain="DAO (E-value: 4.5e-10, bitscore: 38.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGRDRRAVRTDPLPGEPSLDGAKTVAVVGGGVAGMAAATALAER
                     GARVVLFEREDYLGGRVGGWPTRLADGSHVTMTRGFHAFFRQYYNLRALIGRVDPRGTA
                     LVGVPDYPLWHAGGHREGFAGLPRAVPWNAMAFLRRSPTFAWQDLSEVDARAALPMLDV
                     SVPGTYDALDHVDAVTYLEHVRFPPAVHALAFEVFSRSFFAHPARMSAAELVTMFHIYF
                     LGSSEGLVFDVAADPFPHGLWQPLARRLEGLRAEVRTGSPVAAVSRGGARRFVVHAGED
                     VEVDAVVLAAEVPGLRAVVAASPDLGTPRWRESIAALETAPPFLVSRYWLDRPVRADRP
                     PFLGTSGYGPLDNVSVLDRYEHEARAWAARSGGAVVELHGYALAEVDDAQRRLLAHLHE
                     VYPETRDARIVDARHELRADCPLFPPGGWRTRPPVVTPEDGVVLAGDLVRIDLPVALME
                     RAATTGFAAANHLLAGWGVRGTPLWSVPTRGRGVVLRAVARRWGRNPAGTDALAHGTRA
                     "
     gene            complement(14815..15534)
                     /locus_tag="BN6_RS24615"
                     /old_locus_tag="BN6_50880"
     CDS             complement(14815..15534)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Methylase involved in ubiquinone/menaquinone
                     biosynthesis"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102466.1"
                     /locus_tag="BN6_RS24615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50880"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_015102466.1"
                     /sec_met_domain="PCMT (E-value: 7e-06, bitscore: 24.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEITAGTVSGAFDTSARGYDRLVGLNPGYHAALRASARALRLPE
                     RGRGARVLDLGCGTGASTAALVEAAPEAEVVAVDASAGMLAAARRKRWPDRVEFVHSRA
                     EDLAAAGVRGPFDAVFAAYLVRNLPEPDPVLRHVRALLKPGAPFVVLDYAIANSALRRA
                     VWTAVCWSVVIPAGWAVTGDRGLYTYLWRSALDFDDADAFRDRLRRAGFTGVRRGSAGG
                     WQRGITHTFLGRAPERG"
     gene            complement(15531..15839)
                     /locus_tag="BN6_RS24620"
                     /old_locus_tag="BN6_50890"
     CDS             complement(15531..15839)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102467.1"
                     /locus_tag="BN6_RS24620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50890"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_015102467.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 1.1e-17,
                     bitscore: 63.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEYLVAALLSVVVVVVLELAVLRTGLFRNPVYWAALAIMFAFQV
                     PVDGWLTKLDAPVVRYADWAISGVRFPWDIPVEDFLFAFSMITLTLALWERRKETAR"
     gene            complement(15832..16167)
                     /locus_tag="BN6_RS24625"
                     /old_locus_tag="BN6_50900"
     CDS             complement(15832..16167)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl_fung"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102468.1"
                     /locus_tag="BN6_RS24625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50900"
                     /product="lycopene cyclase domain-containing protein"
                     /protein_id="WP_015102468.1"
                     /sec_met_domain="Lycopene_cycl_fung (E-value: 9.1e-17,
                     bitscore: 60.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERWQYAALMVLCLAVTVPLEPLGAGVYRRGAGAVVRAVFPVVVV
                     FGAWDLVAIARGHWTFGSEFISGVVLPGGMPIEELLFFVVVPLCALSTYEAVGSVIRRV
                     TTRGVSA"
     gene            complement(16378..18630)
                     /locus_tag="BN6_RS24630"
                     /old_locus_tag="BN6_50910"
     CDS             complement(16378..18630)
                     /EC_number="1.11.1.6"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102469.1"
                     /locus_tag="BN6_RS24630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50910"
                     /product="catalase"
                     /protein_id="WP_015102469.1"
                     /transl_table=11
                     /translation="MVSKNPAEVVVSALKKAVEKVTEAAEPAIPGAPGSEPPSVAEPTE
                     PREPLPPKPDQDAPETVTPTGAPTGAPKTANSQQGAFLTTAQGVRLYDTDHSLKAGERG
                     PTLLQDHHLREKIMHFDHERIPERVVHARGAGAHGVFVGYGTAENICKAGFLKEGVSTP
                     VFVRFSTVVGSRGSADTVRDTRGFATKFYTDEGTFDLVGNNIPVFFIQDGIKFPDIIHA
                     VKPHPDREIPQAQSAHDTFWDFVSQHTEATHHMMWHVSDRGVPRSYRTMEGFGVHTFRL
                     VNEAGETSLVKFHWKPKLGVHSLLWEEAQMISGFDPDFHRRDLYDAIESGAFPQWEFGV
                     QVFPDTPDQTFEGIDLLDSTKIVPEELAPVQPIGMLTLNRNPTNFFAESEQVAFHTGHL
                     VPGIDVTDDPLLHARLFSYLDTQLTRLGGPNFGQIPINRPHAPVNDMLRDGFHQHAVHG
                     GVAPYKPNSLDGGCPFFAGSKDLAYVEVPQRVAEATKVRKAPESFADHFTQPRQFFHSL
                     SPLEQEHVIRAITFELGKCYEQAIKERQLLVLAKVDTRLAAEVATGLGLPAPEAEALPE
                     VVPSPALSQLGQEWPIDGRMVGIVVDADAPDGLDGVAAVREALFAAGVVPLVIAAHGGE
                     LGQGLVAQRTFATARSVEFDALLLAATPPPAPDALPARDEKATGGSPVDPRVDLLVEET
                     YRHAKAIGAWGTAAVGSGPGIVTGDNPTEVAEQVLTLMRQHRVWNRLTAGQEPPQA"
     gene            18797..19798
                     /locus_tag="BN6_RS24635"
                     /old_locus_tag="BN6_50920"
     CDS             18797..19798
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102692.1"
                     /locus_tag="BN6_RS24635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50920"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_015102470.1"
                     /transl_table=11
                     /translation="MTHTLHALGAAALPTPRGPLSEAVITALRSDPSQWSAPTGVDGDD
                     PYGDDLQLALHVCYELHYRGFHDAAPGWEWDPDLIRLRSAMEQVFHDALNADLPGHPDV
                     NEVLDELLVEPVNGQGLSHHLLDQGQWWQMREHFAHRSIYHLKEADPHAWVIPRLTGRA
                     KAALVAVEYDEYGGGHGDRMHSQLYARLLAGADLETGYLHYLDHAPAPTLATVNLMSLF
                     GLHREQRGALVGHFAAAEITTAPSATRMATALQHLNAHPDCIEFYTEHIEADAVHEQVM
                     RHDVIGDLLTREPELTDSIVFGIRATELLEQRLTDHTLTAWTDNHTSLLTPL"
     misc_feature    complement(18801..18819)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(19800..19994)
                     /locus_tag="BN6_RS24640"
                     /old_locus_tag="BN6_50930"
     CDS             complement(19800..19994)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102471.1"
                     /locus_tag="BN6_RS24640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50930"
                     /product="CDGSH iron-sulfur domain-containing protein"
                     /protein_id="WP_015102471.1"
                     /transl_table=11
                     /translation="MPTPRDKRRVTIVPGGPMLVEGPVELVLDDGTVVESDRFVVAVCA
                     CRRSKRFPFCDTSHRARRR"
     gene            complement(19978..20625)
                     /locus_tag="BN6_RS24645"
                     /old_locus_tag="BN6_50940"
     CDS             complement(19978..20625)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102472.1"
                     /locus_tag="BN6_RS24645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50940"
                     /product="HemK2/MTQ2 family protein methyltransferase"
                     /protein_id="WP_015102472.1"
                     /transl_table=11
                     /translation="MWMLRPPGVYRPQEDTWLLAEALVDAGIPSGASVLDACTGTGFLG
                     VAAGLAGAGEVTAVDISRRAVASARINGWVRGVAVRALRTDFAGLVGRSRFDVVLSNPP
                     YVPSPPGVPKGAARAWDAGERGRSVLDRLCTALPSLLVDRGMALIVHSELCDGDRTLDR
                     LREGGLKAAVVARRTVPFGPVLRGRARWLRDKGLLASGQDREELVVIRADAA"
     misc_feature    complement(20625..20639)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.9"
                     /tool="antismash"
     gene            20799..22082
                     /locus_tag="BN6_RS24650"
                     /old_locus_tag="BN6_50950"
     CDS             20799..22082
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102473.1"
                     /locus_tag="BN6_RS24650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50950"
                     /product="APC family permease"
                     /protein_id="WP_015102473.1"
                     /transl_table=11
                     /translation="MSTSLKRAASTSLLYFFVLGDILGAGVYVLVGQVAAEVGGAVWLP
                     LVTALLLASLTAASYVELVTKYPRAGGSAHYATRAFGPAAGSLVGFCMVAGGVVSVAAL
                     ARAFAGDYLDALVGLPTVPVVVVFLAALAALNIRGVRESLRANAVATVIEVGGLVLVIG
                     LGAWVVLRGDADLSRLSQVDTGGGAVQAVLAGTVLAYYSFVGFETSVNLAEEVRDPRRS
                     YPRALFGALATAGAVYLLVGAVTSAVVPTDRLAASDGPLLEVVRAAGGVPGWLFGVIAL
                     VAVANGALLTGIMSSRLAYGMARDGLLPTALTRVLPGRRTPWVAVLVTSAASLVLALTG
                     EVAALAETLVLLLLVVFTAVNAAVLVLRRDEGEVDHFRVPVVVPCLALASCLLLFTQVD
                     GEVWLRGLLLVGLGAVLAAANHFRRRTA"
     gene            22157..22519
                     /locus_tag="BN6_RS24655"
                     /old_locus_tag="BN6_50960"
     CDS             22157..22519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102474.1"
                     /locus_tag="BN6_RS24655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50960"
                     /product="hypothetical protein"
                     /protein_id="WP_015102474.1"
                     /transl_table=11
                     /translation="MPVLTRLLGVATAAYGAAIVAEPKFLARPCGLADAHGNVAPAVRT
                     MVGGIGARDLAIGAAMVFAPAGTPTRVAVAARVASDLADALVFGLTLPDRAARPKVAAF
                     AVTWAVACAVSAFGKK"
     gene            complement(22607..23080)
                     /locus_tag="BN6_RS24660"
                     /old_locus_tag="BN6_50970"
     CDS             complement(22607..23080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005165434.1"
                     /locus_tag="BN6_RS24660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50970"
                     /product="DUF6292 family protein"
                     /protein_id="WP_015102475.1"
                     /transl_table=11
                     /translation="MRVEWDFDDSVVRALQSYVRLVADELRLSGESSYVQVEPPRSVYV
                     ALDGRLPGYPDRDVALVWDETAGWAVALETHSGEDLIVQARFGADRVPPPAAVARWVRQ
                     VFDGQPTTGTRTAADGWSKGDLAVRLAPYAGSGRGTRPWRDVHLLDVAEHSVQ"
     gene            23363..24826
                     /locus_tag="BN6_RS24665"
                     /old_locus_tag="BN6_50980"
     CDS             23363..24826
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982109.1"
                     /locus_tag="BN6_RS24665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50980"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_041317975.1"
                     /transl_table=11
                     /translation="MDHSEVPVLDALQDFRDHGYTPFNPPGHRQGRGVDPRVLDVLGRD
                     LFAADVITPNGLDDRRTTGRVLERAQELMADAVNADHAFFSTCGSSLSVKSAMLAVAGP
                     HEKLIVPRHAHKSVISALILSGVCPVWIAPHWDAERHLAHPPGPDEVRALFRAEPEAKG
                     MLLVTPTDYGTCGDIRAVAEACHEFGKPLIVDEAWGAHLPFHPDLPPWAMDADADLCVT
                     SVHKSGAAVEQSSVFHLQGDRVDPAALKAREDLLGTTSATSLVYASLDGWRRQMVQHGK
                     ALLTSDLALARTTRASLDELPGLRVMGEAEFTGPSLADSLDPLKLVVDVSGLDISGYQA
                     ADWLREHRRVTVGLSDHRRIVAHFTHADDERSAGVLVDALRALTRDAGSLPTPKPVDLP
                     SPRELQLETAMLPRDAFFATVEQVPADQAVGRIAAEMITPYPPGAPAVLPGEVITREIL
                     DYVRSGLAAGMVLPDPADPDLESVRVVAR"
     gene            24937..25932
                     /locus_tag="BN6_RS24670"
                     /old_locus_tag="BN6_50990"
     CDS             24937..25932
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-168). E-value: 3.1e-15. Score:
                     48.5. Matches aSDomain:
                     nrpspksdomains_BN6_RS24670_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015102477.1"
                     /locus_tag="BN6_RS24670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_50990"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_015102477.1"
                     /sec_met_domain="adh_short (E-value: 5.9e-33, bitscore:
                     113.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKQLSEQVVVVVGASSGIGRATALRLAARGARVVCAARNLPALD
                     TLVAQIGERAMAVRTDITDEAAVHALARAAEQRFGRIDTWVNVAGVGVVGRVEDVPAAE
                     FDRVMRVNFLGHVHGVQAALPALRRAGGGAVIGISSVEGVRSVPWQAPYAASKFALRAL
                     YDSLRVELAQTGDPITVTTILPAAVDTPFFEHSRTHLGVLPKPPAPVYAPELVADAVAT
                     AAEHPRREIPVGGAAAVFFLGQRLFPAMTDALMSVRALAEHLSRKSGPDNEVDNLHTTV
                     AGPGRIRGSYPGRVMRRSLFTTLASRLPRPGEILAAAVSRSNGSNGSNGR"
     aSDomain        24961..25440
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN6_RS24670_PKS_KR.1"
                     /evalue="3.10E-15"
                     /label="BN6_RS24670_PKS_KR.1"
                     /locus_tag="BN6_RS24670"
                     /protein_end="168"
                     /protein_start="8"
                     /score="48.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVVVGASSGIGRATALRLAARGARVVCAARNLPALDTLVAQIGE
                     RAMAVRTDITDEAAVHALARAAEQRFGRIDTWVNVAGVGVVGRVEDVPAAEFDRVMRVN
                     FLGHVHGVQAALPALRRAGGGAVIGISSVEGVRSVPWQAPYAASKFALRALYDSLR"
     CDS_motif       24964..25038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BN6_RS24670_0001"
                     /evalue="3.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="BN6_RS24670"
                     /protein_end="34"
                     /protein_start="9"
                     /score="19.9"
                     /tool="antismash"
                     /translation="VVVVGASSGIGRATALRLAARGARV"
ORIGIN
        1 ggcgcgctgg tgcacctcgc cgccctggcg ggcgtgccct ggctgccgca gacgttcctg
       61 gtgccggtcc gccggcacgg catccacccc gaccggccgc gcgaggcgat gacggcactg
      121 gccgacgcgc gcgccgcctt cctgggcgcg aacccgcacg tggccgtgca ccacatgcac
      181 gacgcgaacc aggaccggct gatgatccgc cacatggcgt acttcaggtt caagtaccgg
      241 cgactgcccg ccgcctacgc cgacttcctg gaccgccacc tggaaccggg cggcacggtg
      301 ctcatctccg actgcgcgga gagccgcccc acgacctcca cggggccgcg gcagttcttc
      361 cagcacggcg cggtgggcgg tgccaccgag gaggagtacg cgcgaggcgg gccgcgcgtc
      421 gccgagttcc tggccgggta cggctctccg gtccgcgcct gggacagccc ggaccccgac
      481 tcgcagagcc cggaggccga gtggggcttc gaccccgcgc tggtccccga cctggcccgg
      541 ctgtgcgcgc aacggggctg gacgctggag cggctcggtt tccccagcgc ccaggcgttg
      601 agcgaaccgg tcgcggaggc ccaccgcgcc tggtacaccg agcagggcgt gaccgcgaac
      661 cggctgctgg tgagcagctt cgcgctgatc gacgcgcacc tgccgttgac cctggggttc
      721 gtcccgtact ggacggtgtt ctccacgctg cccgcgcgag acgcgctcga cgactacctc
      781 cgccgcgcgg cggcgtacga cgagatccgg ctcggtgtct tctcgcacgg cacccggtcg
      841 atcgggttgg ccacccccgc cgactgggac ctcgtcctga gccgcgcgcg gcacggtgcc
      901 tgctgcgggg tcgaccgggc cgcgttcccg ctggacttcg ccgccaacgc ccggttccac
      961 gagcaggcgg ccaagctccc accggccgcg aaccgacccg ggccggcacc gtggacgtgg
     1021 gtgcgggacc ggctgggcgg tcacatcgaa ccggtggggt cggtgggcag ccgctgacgg
     1081 tcaggcggtg ctcaggagcc cgcccggtcg agcccgcagt ggacggccga ggcgtacacc
     1141 tcggcgatgc cgcccgccac ccgctcgatg ccgtaccggg ccgacacccg gtccgtcccg
     1201 gcgatggcgt aggcctcgcg gcgggcggtg tcgaccagca gcccgttcag caggcggctc
     1261 agcccgccgg tcccgcgctg gctggggatc atgccggtga cgtggttcac gaccacgtcg
     1321 gccatgccct cggtggtcat ggtggagacc acggcgaccc cgcaggccat cgcctgcatc
     1381 gccagcaccg acggtcgctc gcaccacggc ccgcacacga cgatgtcggc cgagcggaac
     1441 aacgccggca ggtcgtcgtc ggcggcggcc aggcgcacca cgcggtctgc cacgcccagc
     1501 tcctcggcga ggtcgtccac cgcgggcgtg ccgtccagca ccagcagttc ggcctccggc
     1561 agcgcgcgca gagcagtgac gagctcgtgc ggcagcccgt ccggcgcggc ggtgacgatc
     1621 cggtgcgtcg acccgcgcag cgcactcggc ccttccggcg cgaagcggcg gcggtccacg
     1681 ccgtagggga cgaccgagac cttggaccgc tcgaccccca ggcgcagcaa cgcgggcagt
     1741 tcgtcgcccg acgtcgccac cacccgcacg gcgctgcggc agacggcgcg ttccacgttg
     1801 acccgctcga cgggtccccg gccggcgtcg tggaaggtgt gcacgaccgg gatgcccagc
     1861 ggccgcgcgg cgaacaacgc cgccagaccg gcggtccagc tgtgggtgtg cacgacctcc
     1921 ggggaactgt ccgaccactg ttcccgcaag gtcgtgacga aagactgcaa ccgctgcccc
     1981 gggcccttgt cgtcggccgc gatccgcgcg ctgtgcacta cgacctcatg accttcaccc
     2041 gaaagcgcac tggacaaatc gacaacggga atgtccgatt cgaccgaggt gaccatcgcg
     2101 atccgcatac gcgtaccttt cccatggaca gcgaaaaagg cagcggctac tggctgaacc
     2161 gtgcgacttc accgtaccgc cccgcgatcg acgcgcaact cggccggcgg tggtgacgca
     2221 cacagtcggc ccttcgtggg cgaacccgtc ttcctccccc ggcccgttac ccgacccgtt
     2281 cgaccaccgc gtgcgggtcc agcgaaccgt cggtcaacgc ccgcgccacc tccgacaccg
     2341 gcacacccgt ccgcacgctg taacgctcca gaaccgcccg cgcgtcctcc ggcccgcccg
     2401 acgacaccgc cagcagcacc cccaccgcct gactcacccc cgcccggtcg tgcaacgccg
     2461 ccaccgtccg ctccgccaac cgctccaccc gacgcggccc acgctcctgg ctcaacccca
     2521 acaccgccag atccgccaac ccctgacccc gccgcaccac ccgctccgac aacctcgtcg
     2581 gcaccgtgta gagcagattc accccaccca ccgcccgacc caacaaccgc atcggaaacg
     2641 cgtagaccgc ccggtaaccc tcccgcagag cagcctccgc gaactccggc caccgccccc
     2701 gcgccccgtc cagatccccc accgcgacca ccgcgtcctc ggcgataccg tccagacacg
     2761 gaccctgacg caactgggcc tgcaacaact ccacgaaccg ggcccgctcg tccgacgccg
     2821 ccgcgacctc cacaccacca cgcggatcca ccaccagcac cccgaccgcg tccgccccca
     2881 acacggccgc acacgccccc accaccgcac gcaggaccgt caacccgtca tgacgagccg
     2941 tcaacaaagc cgtgatcccc acgacatggt catcgaaatc ccgcgacggc acactcaccc
     3001 ggccagcata aggccgaccg atcacacgga ccgcacagcg cgatggcggc tcactccgcg
     3061 gccgagtcca gccgcagttc ccggctgagc acctgccgcg ccacctcagt caacgggagc
     3121 tggttgctgt aggcgtacgc acgcagccgc agcaacgcgt cctccaggtt gatctgcaac
     3181 aacgtcgcca gcatcccgat cgccatgttc acgtcgtcat agaacgacga cacgtcctcg
     3241 cgggcccacg acgcgaccgg cttctcgtcc ttgctgtcgg tcaacaacgc ggtcgtcgcc
     3301 aagtcggcga gcgcgaccgc gtcaccgaac ccctccgcat ccaacggacc ggcgcgatgc
     3361 cggtagaggg cgaaggtccc cacttggatc gcgccgaccc gcaacgggaa cgcgaacgcg
     3421 gcacgaacgt cggcggtcgc ggcctcgtgc acgaagccgg gccagcgtcc ggcctcggtg
     3481 ttcagatcac cgaccagcac cgcttctccg tcgcggaacg ccgacatccc cgggccctcg
     3541 cccaccgtgt actgcaactc ctccaacgac gccgcccacg cgtcactggc tgccgccaac
     3601 tgctgcgtcc gccccgccgc gcgcaccgtg atcgcagcgg cgtccacgtc gatccgcccc
     3661 aaggccaccg cgcacaccgc gctcacccaa cccgaagccg gcggatgatc ctgggcgtag
     3721 gtggtgacca gccgccacag ctcctcgtgg cgccgaccat ccacaacccg ccacctccac
     3781 acggccgcca cacgccacgg acggcccact cctcgcctgg gcacatcatc gcgcactcac
     3841 gaacggggcg ccggccgcct atgcccaccc gggaccacgg gcatggcggg gccgcgcgcc
     3901 gatcagcgag gaggactcgc atcgcaggcc gtgaccggcg aggaaccgcc cggccaggcc
     3961 ggtctaccag gcctcgtgaa cgggccggtg tccgttcagc gcccgagcgc ggaggcgagt
     4021 tccttcttcg tcatcgtgga gcggcccttg atgttcttct tcttggcctc gttgtagagc
     4081 tggtcacggg tgggcccctg cggcccctgc cggttgccgg agcgctgccc gccacggcgc
     4141 tgcggcgagg tgtcccgggt cgacgtccga ctggccgtct tcgactcgcc ggcctgcgcc
     4201 cggttcttgt tcacggtccg ggcggcgatc tccttggcgc gtttcgtaga ctcgccgcgc
     4261 tccttcgccg aatccttgat gtgctcgtac tggcgctccc gcttggcgtt cgatccgctt
     4321 ggcatggcaa acctcctttt ccagtcctca ggtacccctc cgaataccgt ccacacctga
     4381 cgccggcggt ggccgcgggt gcgctcgatc ggctcgtacc gcgcccggcc gggtgtggaa
     4441 cgccttgtgc cgggtagccg cccgctggag cgggacgacg gtgtcgagga gggaacggca
     4501 tgtccgagac ggtcggcgac tacgtgctcg ccaggctgcg tgactggggc gtcgagcagg
     4561 tgttcgccta tcccggcgac ggcatcaacg ggatcgtggc cgcgttcggc aaagcggacg
     4621 acaacccgcg gttcgtgcag tcccggcacg aggagatgtc cgcgttcgag gcggtcggct
     4681 acgccaagtt cagcggcaag gtcggggtgt gcctggccac ctcgggtccg ggcgcgatcc
     4741 acctgctcaa cggcctgtac gacgccaagc tcgaccacgt tcccgtggtg gcgatcgtgg
     4801 ggcagaccgc gcgcagcgcg atgggtggca gctaccagca ggaggtcgac ctgcaagcgc
     4861 tgttcaagga cgtggccagc gcctacctcg tggaggtgaa cgtcgccgag cagctgccca
     4921 acgcgctgga ccgggcgatc cgcgccgccg aggccgaacg cgccccgacc gcgatcatca
     4981 tccccagcga ccttcaggaa gaggagtaca cgccgccgaa gcacgcgttc aagcaggtgc
     5041 cgtcgagccc gccgagccgg gtgaagtcgg tgctggtccc ggaccaggac gagatcgcgc
     5101 gcgccgccga ggtgctcgac gcgggcgaga aggtggcgat cctgatcggc cagggcgcgc
     5161 gttcggccgc cgaggaggtc gtccaggtcg cggagctgac cggcgcgggc gtggccaagg
     5221 cgctgctggg caaggacgtg ctgtccgacg aactgccgtt cgtcaccggg tcgatcgggt
     5281 tgctgggcac ccgtccgagc tacgagctga tgcgcgactg cgacacgttg ctcatcgtgg
     5341 gctcgaactt cccctacagc cagttcctgc cgccgtacgg gcaggcccgc gcggtgcaga
     5401 tcgacatcga cggcaagttg atcggcatgc gctacccgac cgaggtcaac ctcgtgggcg
     5461 acgccggggc gacgttgcgg gcgctgctgc ccctggtgcg ccgcaaggcg gaccggacgt
     5521 ggcgggagaa gatcgagggc gacgtccgcg actggtggga gaccatggac cggcaggccg
     5581 cgctggacgc caagccggtc aacccgatgc ggatcgtgtc ggagctgtcc gccagggccc
     5641 cgcacgacgc gatcttcacc gcggactcgg gttcggccgc caactggtac gcccggcacc
     5701 tgcggatgcg cggggacatg cgcggttcgc tgtcgggcac gctggcgacg atgggtccgg
     5761 gcgtgccgta cgcgatcggg gccaagttcg cccaccccga ccggccggtc atcgccctgg
     5821 tgggtgacgg cgcgatgcag atgaacggca tggccgagct gatcaccatc gcccgctacc
     5881 gggagctgtg gtccgaccag cggctggtgg tgtgcgtgct gcacaacaac gacctcaacc
     5941 aggtcacgtg ggagctgcgg gcgatgggtg gcgcgccgaa gttcgagcag tcgcagaccc
     6001 tgccggacgt ggactacgcg ggtttcgccc gctcgctcgg cttggccgcg atcaccgtcg
     6061 acgccccgga ccagctcggc cccgcgtggg accgggcgct gaccgcgagc gtgccgaccg
     6121 tgctggacgt ccactgcgac ccggaggtgc ccccgatccc gccacacgcc acgttcgacc
     6181 agttcaagtc ggtcaccgaa gcgatcctca agggcgaccc ggcggcgtgg catctgatgg
     6241 cgcagggcat ccgcaccaag gcgcaggaac tgctgccggg caagcgctga ccccacccgg
     6301 ggcgctcgcc gcgacccacg gatccggatc cgcgaagggg cctggagcgg gtcggtcgcc
     6361 accggcgcac cggtggcgac cgatccgccc acccggggtc agggcttggg ccaccagaac
     6421 cagtcggcgc aaccgctgtg gtcctcacag acccggaacc gggcgatctg ggcgtcgaag
     6481 cagctcgccg ggccccagtt cccgtcggat ccgttgccgt cccacaccga gaagtggcgg
     6541 tcgtcggcga ggacgacgtc ggcgtagacg ccgttgccgt cggcctcgcc gtcgtaggcc
     6601 gcggcgcagc gctcgtccgc agcggcctgg ttcgcgcccc ggctcaggac cgtcgcctgg
     6661 gcctgaccgg caccgaggac caccaaggcc gtcgtcgtcg cggtgagcag cgccgcggac
     6721 agcagccgtg cgggacggcg cggagaaggt gatgtcatgt cgtcactcct tcgatggagg
     6781 tgtcgccggt ccgaggcccc gagcaggtgc tccgaagctg gttccgacgt ggtggacgac
     6841 tccgttctag gccgtcgggg tgtcccacca tcaggtgttg cggctggtcg ggacggtggg
     6901 acaggctggg acacagctca gccggggcaa gtgggacaga ccccggccga ccgcgcgccc
     6961 gaggagcccc gattggccga ggacaccccg cccgggagca ccgacgcgcc cgacccgcgc
     7021 acggcgaccg acatcgcgat gttcgtggaa ctgctgcggc ggcttcgcac gcgggcgggc
     7081 aaccccggct acaagaagac cctggagcgg gcgacccggg acgagcacgg catccccagg
     7141 atcagcgggt cgaccctcca ccgggtgctg gaaggtcacc aggacctggc ccggatgcgc
     7201 gatccggacg ttttcgtccg cgagctggta accgcgctcg gcgcgaaccc gcgaccgtgg
     7261 tcggaggcgc tcgaccggct gctgcacccg gcgacgccgg aacccccggt cgagcccgcg
     7321 accgacacca caccggtcag gcggacccgg cgcggactcc tggccgtgac cgcggcggtg
     7381 ctgctggtgg cggccggggt cgtggtctgg tcgaccgccg ggccgcacga accgccggcc
     7441 gcgcccccga ccggccccgt ccggctgtcg atcagcctcg ccgccgatcc cgcgctgagc
     7501 ctggccgtcg acccgacggc cgacccctcg gtcacccaca cgatcctggc cgacgacgcc
     7561 gccggcaccg gctgggagat ggtcgccccg taccacgccg ggccccggtc ctggcagctg
     7621 cgggcctcgg ggcggctgct gtcgtgcctg gaagtactgg gagccggtta cgcggagggc
     7681 acgctggtcc agcagtacgg ctgcaacggc agaccgcacc agcactggac gcccgaacca
     7741 caggaggacg gcaccctgcg gtggatcaac ttccactccg agcagtgcct caccgccgcc
     7801 ggcacccgac cgcgcgccgg aaccgaactg gtgcagcgcg agtgcgaccc ggcgcgcgca
     7861 gcgctccagc agtggcgcgt gaccacgatc gacaccccgc tcccgcccac cgtgccgaac
     7921 agcgtcgtcc cgggccgccc gggtccgggg ccgacggact acccgggtgg cggcaaggac
     7981 cacccctgcc acggcgtcgg cccggcactc gacccgaggg ccaccgcctg ggccgcgcaa
     8041 ccctccccgg tcggtgggca agaccccggc gggggccggg tgtcgatggg cccggacacg
     8101 gccggcgcgg tcgagctgat gcacgccacc aggaccaccg acaccggcga ccacaccttc
     8161 tactgggccg agggctggat cgcgttcagc ccgcacctgt tcaccatgtc gttgcagtgg
     8221 accaccgcac ccggctccgg cgactggcac acctgcaccg tcccgttcac caccgagcac
     8281 ggtgcgcacg ggcggcccgc caccaccgcc ctgccccgct cccccgacgg caccggacac
     8341 ctggccttcc ggacctgcat cacctacacc cccgaactgg aaccccggga accgatgatc
     8401 aactgctccg gccgccactg atcacgcccg cgccggcctt gcccgaactg ccgcaccggc
     8461 ggaacctgag aggcaccgca cgggcgtgcc ggcggggctc agtcggcggg ggtgcgcagg
     8521 cgtcgggccg ccaacctgcc ggagatcagc acgggcggga taccgacgcc cggtgtcgtg
     8581 ccgctgcccg cgagcaccac gttgccgcgt cggaacggga ggttgcgcgg gcggaacggg
     8641 ccggtttggc cgaaggtgtg ggcggccgag aacggggtgc ccgcggcctg tccgccggcg
     8701 gcccagtcgt cgggggtgct caaggcgatc ctggtgacgt cgtcggcgga ggcgatcagc
     8761 ccgcgtcgca ccagggtgtc caccaggtcg tccgcgtagc cggaaccacg caggtcccag
     8821 cgcagcgggt tgcggtcgag gttcgggcac ggcgccagca ggtagtgcag gtcccgaccg
     8881 ggcggggcca gcgacgggtc ggtgcgggtc ggggtggtga gcagcaacga cgggtccgac
     8941 atcagccgac cgcgggagat gatctcgtcg aaggtggtct cccaggcgtc gccgaacgag
     9001 atggtgtggt gcgcgaggcc gtccaccacg cgccgcgcgc tcaagtgcac gaccaccgcc
     9061 gagggcgacc accggagggt gcgccggggt cggccgcgca gcagccgggt ggtctgcccg
     9121 ggtccggtgg ccagcacgac cgcgccgcac gggatgcggt cgccgccgac caggaccgcg
     9181 gtgacccggt cgccggtccg ctccagcgcc agcgcctcgg tgtcgcggcg cacctcgatc
     9241 ccggcggcga ccgccgcggc ctccatcgcg gcgggcacct gccgcatccc gccgcgcggg
     9301 aaccacaccc ccgcgacggt gtccatgtag gcgatgacgg cgtacgcggc caaggcgtcc
     9361 tggggcgcga cccccgcgta gagcgcctgg aaggtgaaca cccgttgcag gcgcggatct
     9421 cgcaggaagc ggctcaccgc gccggtcagg ttgccgaacc cgcccagccc ggccagcgcg
     9481 gcgaggtccc ggccgaccag gtcgagcggc gagtcgaagt tggccgcgat gaaccggtcc
     9541 cgctgcacct cgtacagccg ggtcagccac gcccgcagcc ggcggtaccc gtccgcgtcg
     9601 gcaccgccgg cgaactcgcg cacggcgtgc tccatcgcgg cggcgtcggt gtgcacgtcg
     9661 atcgcgctcc cgtccgcgaa gaccgcgcgg taggcggggt ccagcggcag cagctccacc
     9721 cggtcggcca ggcggtcccc gacggccgcg agcgcctcgt ccaccagttc gggcatcgtc
     9781 agcacggtcg gcccggtgtc gacgcggtgc ccgtcgacgt ccagcctgcc catcaggccg
     9841 ccgcagtggg cggcctgctc cacgacgacc acctcgtgcc cgtcgccgcg caggtgcagc
     9901 gcggcggaga gcccggcgag ccccgccccg accacgacga ccgggcgggg cgatgcccgc
     9961 ctcgtcacgg cggcggtccg gcggccggaa ccggcggggt tcaccgcgtc ctcgccgtgg
    10021 cctgctccgc caacgcgacc aggcggtcac gggcggccgg gacgagggcg gcggcgtcga
    10081 gcgcgcgcag cccggacgtg gtcagcgcgg ttatccgctc ctcgatcacg gccaccgcgc
    10141 ccaggtcgtg cagcagcgcc cgcacgtggg ccagctcgtg gtcggtggcc ccgccttcca
    10201 ggcagtcgcg cagcgcgcgc acggcgtccg cccggccggc ggtgcgggcc aggccgagcg
    10261 cggtcgccat cagcggggtc cgcttgccct cccgcaggtc ctcgcccacc ggcttgccgg
    10321 tcacgcgcgc gtcgccgaac gagcccagca ggtcgtcgcg gagttggaac gccacgccga
    10381 tgtcacgacc gtaggcccgc agtgcgtcga tcacggccgc cggcgcgtcg gcgacggccg
    10441 cgccgaggtg cagcgggcgt tcgacggtgt acgcggcggt cttgagccgg gcgacccgca
    10501 gaccggccgc gaccgattcc gaccgggtcg caccgccgag caggtcgagg tgctggcccg
    10561 ccatcatctc cgtccgcatc gcctgccacg gctcccacgc gcgggtcagc gccgagccgg
    10621 gcagcccggc gcggaccagg gcgtcgtccg cccacgccag agccaggtcc ccgaccagga
    10681 tcgcggcgca gtcgccgtag tgggtggcgt caccggccca gcgctcacgg cggtgccgcg
    10741 cggcgaacac ccggtgcgcc gtgggacggc cgcgccgcgt ggccgagcgg tccatgacgt
    10801 cgtcgtggat gagcgcgcag cactggagca gctccagggc gaccagggcg cgcaccaggg
    10861 cgtcggcttc cggtccgccg gccgcgcctc ccgcggcgcg ccacccccac caggcgaagg
    10921 tggggcggag ccgcttgccg ccgccgagcg ccagatcggc gagcgcgtcg cccagttccg
    10981 gcgcgagccc gccgtcgcgg cgcagtgcca ggtagccctc cagctcctcc cccagacgac
    11041 gggggaggtc gtcgtccacg gtcggcccga cagcggtcag cgacatgcgg cctcctcgca
    11101 cggtggtgtc ctctgccaac caagcagccc cgccggactg ccgcatgatg aacgcgcctg
    11161 tcgtgcggac gggtcggcgt cgatctagcg tgggtcccgg gtgcccgagg acgaggagtc
    11221 gaaccctgat gtctgccgat cgagaactcg acgcggcgaa gatcaccgac ccggccatgc
    11281 gcgcggcgta ccggcggtgc cgggcgctca acgccgagca cgggcggacc ttctacctgg
    11341 ccacccgtct gctcccgccc gaccggcggc ccgcggtgca cgcgctgtac gggttcgccc
    11401 gctgggtgga cgacatcgtg gacgaggtgg acgacggccg caccgccgcc cagcgcgcgg
    11461 cggaactgac ggcggtggaa ggtcttctgg agcagggcct gcggacgggc gcgagcgaca
    11521 acccggtgat ctcggcgctg ctggacacct cgggtcgcta cgggatcccg cgcgcccact
    11581 tcgaggactt catgtcctcg atgcggatgg acctgaccgt gaccgactac ccgacgtggg
    11641 acgacctcgc ccggtacgtg cacggttcgg cggcggtgat cgggttgcag gtgctgcccg
    11701 tgctcggcac gaccgtgccc cgggccgaag ccgagcccgc ggcggcggac ctgggcgtcg
    11761 cgttccagct cacgaacttc ctgcgcgacg tcggcgagga cttggaccgg gggcgggtct
    11821 acctgccggc cgacgagctc gcggcgtccg gtgtggaccg cgacctgctg gtctggtcac
    11881 ggcggaccgg acgcgccgac cagcgcgtcc gcgacgcgtt ggcggcccag gtggcgcggg
    11941 cccggcgcgc ctaccgggcg gccgaaccgg ggctgcgcgt gctcgacccg cgctcgcggc
    12001 cgtgcgtggc gaccgcgttc cggctctacg ggcggatcct cgacctcgtc gaacgcgccg
    12061 actacgacgt gctgtcgcgg cgggtggcgg tctcgcaggg gcgcaggctg gtcgtcgcac
    12121 tgcccgccct cgcccgcgcc gccttcgccc actgacagcg ccgattgacc gcgcccaccg
    12181 acagcgccca ctagcagcgc ccactccact cgtccactcc actcgtccac cggcttcgtc
    12241 cacgtccgac cggtcccgct ctccaggggg aagacacgtg cccaaactcc cgctgcggct
    12301 gttccgcagc cgtccgtggc ccgagcagga accgacttgg cgggccgccg caccggcgct
    12361 gatcgggtcg gcgctggccc gcgccaccgc ccgcccctcc gggaactggt tcacggtgtg
    12421 cgccagccgg gaggtgcccg gcgaccggcc gttcgggcgc acggtggccg gccgcgaggt
    12481 cgtcctctgg cgcggtgccg acggcggcct gcgcgccggg ccgggcgcgt gcccgcacct
    12541 cggcgcaccg ctgcgcgacg gcgtcgtgca ccggggcgag gtggtgtgcc ggtggcacgg
    12601 cctggccctg ggcgaggcga agttcggccg gtggagcccg tacccggcgc acgacgacgg
    12661 ggtgctggcc tgggtgcggc tggacgacgt gggcggtgag gacccgctgc ccgcacccgt
    12721 gctgcccgcg cgaccgccgg ccggggcgat cgaggcggtg accacggtga tcggccggtg
    12781 cgagcccgag gacgtggtcg cgaaccggct ggacccgtgg cacggggcgt ggttccaccc
    12841 gtactcgttc gcgaacctgc gggtggtggg cacccccacc gacgacgagg accggttcct
    12901 ggtcgaggtg acgttcaagc tggtcggtcg ggtgggggtg ccggtggtcg cggagttcac
    12961 ctgcccggaa ccccgcacgg tggtgatgcg catcgtctcg ggcgagggcg tgggcagcgt
    13021 cgtggaaacg cacgccactc ccctgtcgcc cggtcccgac ggcgcgccgc gcaccgcggt
    13081 gatcgaggcg accgtggcgc actcgtcccg ccggggtttc gcgttgaccc gccccgccgc
    13141 gccgctgatc cgcccggtga tgaggtgggc ggcggccagg ctgtggcgcg acgacctcgc
    13201 ctacgccgaa cgccggtacg cgttgcgggc gtgaggcgtc acgcctcgtc gcgggcgtga
    13261 ggcgtcacgc ccgcgtgccg tgcgcgagcg cgtcggtccc ggccgggttg cggccccacc
    13321 tgcgggccac cgcgcgcagc accacgcccc gccccctggt cggcacgctc cacaacggcg
    13381 tcccgcgcac gccccacccg gccagcaggt ggttggcggc ggcgaaaccg gtggtggcgg
    13441 cgcgttccat cagcgccacg ggcaaatcga tgcggaccag gtcgcccgcc agcacgacgc
    13501 cgtcctccgg ggtgacgacc ggtggcctgg tccgccagcc accgggcggg aacagcgggc
    13561 agtccgcgcg cagttcgtgg cgggcgtcga cgatccgcgc gtcacgggtc tccgggtaca
    13621 cctcgtgcag gtgggcgagc agccgccgct gcgcgtcgtc cacctcggcc agcgcgtagc
    13681 cgtgcagctc gaccaccgct cccccgctcc gggcggccca cgccctggcc tcgtgctcgt
    13741 agcggtcgag caccgagacg ttgtccagcg ggccgtagcc gctggtgccg aggaagggcg
    13801 gccgatcggc gcggacgggg cggtccaacc agtaccgcga caccaggaac ggcggcgcgg
    13861 tctccaaggc ggcgatcgac tcccgccacc ggggcgtccc gagatcgggc gaggcggcca
    13921 cgaccgcgcg caggccgggc acttcggcgg ccagcacgac cgcgtcgacc tcgacgtcct
    13981 cgccggcgtg caccacgaac cgccgcgccc cgccgcgcga caccgccgcg accggcgagc
    14041 ccgtgcggac ctcggcgcgc aacccctcca agcgacgggc cagcggttgc cagaggccgt
    14101 gcgggaacgg gtcggcggcg acgtcgaaca ccaggccctc ggacgacccc aggaagtaga
    14161 tgtggaacat ggtgacgagc tcggccgccg acatccgcgc cgggtgggcg aagaagctgc
    14221 gggagaacac ctcgaacgcc aaggcgtgca cggccggggg gaaccgcacg tgctccaggt
    14281 acgtcacggc gtccacgtgg tccaacgcgt cgtacgtgcc gggcaccgac acgtccagca
    14341 tcggcagggc ggcacgggcg tccacttcgg acaggtcctg ccacgcgaac gtcgggctgc
    14401 gccgcaggaa cgccatcgcg ttccacggca ccgcgcgtgg cagcccggcg aacccctcgc
    14461 ggtgcccgcc ggcgtgccac agcgggtagt ccggcacacc gacgagcgcc gtgccccggg
    14521 ggtcgacccg gccgatcagg gcgcgcaggt tgtagtactg gcggaagaac gcgtggaagc
    14581 cgcgggtcat cgtgacgtgg ctgccgtcgg ccagccgggt cggccacccg ccgacccggc
    14641 cgcccaggta gtcctcccgt tcgaagagca cgacccgggc accgcgttcg gccagcgccg
    14701 tcgccgcggc catccccgcc acgccgccgc cgacgacggc caccgtcttc gcgccgtcga
    14761 gggacggctc gccgggcagc gggtcggtcc gcaccgcccg ccggtcgcgg cccttcaccc
    14821 gcgctccggg gcacgcccga ggaacgtgtg cgtgatcccc cgctgccagc ctcccgcact
    14881 gccccggcgc acgccggtga acccggcgcg gcgcagccgg tcgcggaagg cgtcggcgtc
    14941 gtcgaagtcc agcgcgctgc gccacaggta ggtgtagagg ccgcggtcgc cggtgaccgc
    15001 ccaccccgcc gggatcacca ccgaccagca caccgccgtc cagaccgccc ggcgcagggc
    15061 cgagttcgcg atcgcgtagt cgagcaccac gaacggcgct ccgggcttga gcagggcgcg
    15121 gacgtgccgc agcaccgggt ccggctcggg caggttgcgc accaggtacg cggcgaacac
    15181 cgcgtcgaac ggcccgcgca ccccggcggc ggccaggtcc tcggctcgcg agtgcacgaa
    15241 ctcgacccgg tcgggccacc gcttgcggcg ggcggcggcg agcatccccg ccgacgcgtc
    15301 caccgccacc acctcggcct cgggcgcggc ctccaccagt gcggcggtgg aggcacccgt
    15361 cccgcagccc aggtcgagca cccgcgcccc cctgccccgc tcgggcagcc gcaacgcccg
    15421 agccgacgcg cgcagtgccg cgtggtagcc ggggttgagc ccgaccagcc ggtcatagcc
    15481 gcgcgcggac gtgtcgaacg ccccggacac cgtgccggcc gtgatctccg tcatcgggcg
    15541 gtctccttgc ggcgttccca caacgccaac gtcagggtga tcatcgagaa ggcgaacaag
    15601 aagtcctcca ccgggatgtc ccacgggaac cgcaccccgc tgatcgccca gtccgcgtaa
    15661 cggaccaccg gggcgtccag cttggtcagc cacccgtcga ccgggacttg gaaggcgaac
    15721 atgatggcga gcgccgccca gtagacgggg ttgcggaaca gcccggtgcg cagcaccgcc
    15781 agttccagca ctacgaccac caccaccgac aggagcgccg cgacgaggta ttcaggcact
    15841 gacacccctg gtcgtcacgc gccggatcac gctgccgacc gcctcgtagg tgctcagcgc
    15901 gcacaacggc acgaccacga agaacagcaa ctcctctatc ggcatcccgc ccggcaggac
    15961 cactcccgag atgaactcgg acccgaacgt ccagtgcccg cgcgcgatcg ccacgaggtc
    16021 ccacgcgccg aacaccacca ccacgggaaa caccgcccgc acgacggcac ccgcgccacg
    16081 ccggtacacc ccggcgccca gcggttcgag cggcacggtc accgccaggc acagcaccat
    16141 cagcgccgcg tactgccaac gctccatctc cgcctcctcc gcgacctcat ccgaccgtat
    16201 tgggcacgac gggttcccgc acaacaggac ccggaccgtc ccggccaccg gggatgcggc
    16261 gccggcaccg accgggcgaa agccgcagcc gggacgggcc ggcggtcctg ccttcgcgga
    16321 tcgacaggac gcccgccgca cgcgggggtc ccacgtgcga cgggcgtccg aagaggctca
    16381 ggcttgcggc ggctcctgac ccgcggtgag gcggttccag acgcggtgtt ggcgcatcag
    16441 ggtgagcacc tgctcggcca cctcggtcgg gttgtccccg gtgacgatcc ccggcccgga
    16501 accgacggcc gccgtgcccc acgcaccgat cgccttggcg tgccggtagg tctcctccac
    16561 gagcaggtcg acccgggggt cgaccggaga tccgccggtg gccttctcgt cgcgggcggg
    16621 cagcgcgtcg ggcgccggcg gaggcgtcgc ggcgagcagg agcgcgtcga actcgaccga
    16681 tcgcgcggtg gcgaacgtgc gctgggcgac caggccctgc ccgagctccc cgccgtgcgc
    16741 ggcgatcacc agcggcacga caccggccgc gaacagcgcc tcccgcaccg cggcgacgcc
    16801 gtcgaggccg tccggggcgt ccgcgtccac gacgataccg accatccggc cgtcgatcgg
    16861 ccattcctgg ccgagctggg acagcgccgg gctcggcacc acctcgggca gcgcctcggc
    16921 ctccggggcg ggcagaccga gcccggtggc gacctccgcg gccagcctcg tgtccacctt
    16981 ggccagcacc agcagctggc gttccttgat cgcctgctcg tagcacttgc ccagctcgaa
    17041 ggtgatcgcg cggatcacgt gctcctgctc cagcgggctc aggctgtgga agaactgccg
    17101 gggctgggtg aagtggtcgg cgaacgactc gggcgccttg cggaccttcg tggcctcggc
    17161 gacccgttgc ggcacctcca cgtacgccag gtccttcgag cccgcgaaga acgggcagcc
    17221 gccgtccagc gagttcggct tgtagggcgc gacaccgccg tgcacggcgt gctggtggaa
    17281 cccgtcgcgc agcatgtcgt tgaccggcgc gtgcggtcgg ttgatcggga tctgcccgaa
    17341 gttcggcccg cccagccggg tcagctgggt gtcgaggtag gagaacaggc gggcgtgcag
    17401 cagcgggtcg tcggtgacgt cgatgccggg cacgaggtgg ccggtgtgga aggcgacctg
    17461 ttcggactcg gcgaagaagt tcgtcgggtt gcggttgagc gtgagcatcc cgatcggctg
    17521 caccggggcc agttcctcgg gcacgatctt ggtcgagtcc agcaggtcga tgccctcgaa
    17581 ggtctggtcg ggcgtgtccg ggaacacctg gaccccgaac tcccactgcg ggaacgcgcc
    17641 ggactcgatc gcgtcgtaca ggtcccggcg gtggaagtcc gggtcgaagc cgctgatcat
    17701 ctgcgcttcc tcccacagca gggagtgcac accgagcttc ggcttccagt ggaacttcac
    17761 cagcgacgtc tcaccggctt cgttcaccag ccggaaggtg tggacgccga acccctccat
    17821 ggtccggtac gagcgcggca ccccccggtc cgaaacgtgc cacatcatgt ggtgggtggc
    17881 ctcggtgtgc tgggagacga agtcccagaa cgtgtcgtgc gcgctctgcg cctgcgggat
    17941 ctcccggtcc gggtgcggct tcaccgcgtg gatgatgtcg gggaacttga tcccgtcctg
    18001 gatgaagaac accgggatgt tgttgcccac gaggtcgaac gtgccctcgt cggtgtagaa
    18061 cttcgtcgcg aacccacgcg tgtcccgcac cgtgtccgcc gaaccgcgcg accccaccac
    18121 cgtggagaac cgcacgaaca ccggcgtcga cacaccctcc ttcaagaacc ccgccttgca
    18181 gatgttctcg gcggtcccgt agcccacgaa cacgccgtgc gcgcccgcgc cacgggcgtg
    18241 caccacccgc tccgggatgc gttcgtggtc gaagtgcatg atcttctcgc gcaggtggtg
    18301 gtcctgcaac aacgtcggac cgcgctcgcc ggccttcagc gagtggtccg tgtcatacag
    18361 gcgcacgccc tgcgcggtgg tcagaaacgc cccctgctgg ctgttcgccg tcttcggcgc
    18421 acccgtcggc gcaccggtcg gggtcaccgt ctccggagcg tcctggtctg gtttgggggg
    18481 cagcggctcg cgcggctcgg tcggctcggc gaccgagggc ggctcgctcc ccggcgctcc
    18541 cggaatggcc ggttcggccg cctccgtcac cttctcgaca gccttcttca acgcgctcac
    18601 gacgacctcc gccgggttct tggacaccac cgggcctcct tctcctcgtc cggcgattac
    18661 ccgagcggat gcggtctaca ccgaagctcc ggcatccgat cggctgggac gagaacacgc
    18721 cgagtcaccg accacttcgg agcgacggcc ggcgtcggcg tgcatcactc cggttggggg
    18781 tgggtattcc actgacgtga cgcatactct gcacgctctg ggagccgccg ccctgcccac
    18841 tccgcgtggg ccgctgtccg aggcggtcat cacggccctg cgatccgacc cgtcgcagtg
    18901 gtccgcaccc accggcgtgg acggggacga cccgtacggc gacgacctcc aactcgcgct
    18961 gcacgtgtgc tacgaactgc actaccgcgg cttccacgac gccgcaccag gctgggaatg
    19021 ggaccccgac ctcatccggc tgcgctccgc gatggaacag gtgttccacg acgcgttgaa
    19081 cgccgacctg cccggacacc cagacgtcaa cgaggtcctg gacgaactcc tggtcgaacc
    19141 cgtcaacggg cagggactga gccaccacct gctcgaccag ggccagtggt ggcagatgcg
    19201 ggaacacttc gcccaccggt ccatctacca cctcaaggaa gcagaccccc acgcctgggt
    19261 catcccccgc ctcaccggcc gggccaaagc cgcactcgtc gccgtcgagt acgacgaata
    19321 cggcggcgga cacggcgacc ggatgcactc ccagctctac gcccgactac tcgccggcgc
    19381 ggacttggag accggctacc tgcactacct cgaccacgca cccgcgccga cgctggcgac
    19441 cgtgaacctc atgtccctgt tcggactcca ccgcgaacaa cgcggcgcac tcgtaggcca
    19501 cttcgccgcc gccgagatca ccaccgcacc cagcgccacc cgcatggcca cagcactcca
    19561 acacctcaac gcccaccccg actgcatcga gttctacacc gaacacatcg aagccgacgc
    19621 cgtacacgaa caagtcatgc gacacgacgt catcggcgac ctcctcaccc gcgaacccga
    19681 actcaccgac tcgatcgtct tcggcatccg cgccaccgaa ctgctcgaac aacgactcac
    19741 cgaccacacc ctcaccgcct ggaccgacaa ccacacctca ctgctcacac cgctgtgagt
    19801 caccgccgac gcgcacggtg actggtgtcg cagaacggga accgcttgct gcggcgacac
    19861 gcgcacaccg ccaccacgaa ccggtcggac tcgaccaccg tgccgtcgtc cagcaccagc
    19921 tcgaccggtc cttccacaag catcggaccg ccggggacga tggtgacccg gcgcttgtca
    19981 cgcggcgtcg gcacggatca ccaccagctc ctcccggtcc tgccccgaag ccagcaaccc
    20041 cttgtcgcgc aaccacctgg cccgcccgcg caggaccggt ccgaacggca cggtccggcg
    20101 ggcgacgacg gccgccttca acccgccctc ccgcaggcgg tccagcgtgc ggtcgccgtc
    20161 gcacagttcg gagtggacga tcagggccat gccccggtcc accagcagcg acggcagggc
    20221 ggtgcacaac cggtcgagca ccgagcgccc ccgctccccc gcgtcccaag cccgcgcggc
    20281 ccctttcggc acgcccggcg ggctgggcac gtacggcggg ttcgacagca ccacgtcgaa
    20341 ccgcgaccgc cccaccaagc cggcgaaatc agtgcgcagc gccctgacgg cgacaccgcg
    20401 gacccacccg ttgatccggg cggaggccac cgcccgcctg ctgatgtcca ccgcggtcac
    20461 ctcaccggct cccgccagac ccgccgccac ccccaggaaa ccggtacccg tgcacgcgtc
    20521 gaggacgctc gcgcccgacg gtatccccgc gtcgaccaga gcttcggcga gcaaccacgt
    20581 gtcctcctgc gggcggtaca caccaggtgg tctcagcatc cacatggaga tgacgttccc
    20641 ggcgcggcac gctccaaaca ggatcacgcc gcgaacgtgc ccacgacgcc ggacgaaccc
    20701 ggcacgacga ccacccgggt cgacggctcg tcgatcccgg atccggacag ccgcgcacgt
    20761 cacgtgtggc cggtgccgcg ccggggaatg gagcggtcat gtcgaccagc ttgaaacggg
    20821 ccgcgagcac gtcgctgctc tacttcttcg tcctcgggga catcctcggc gcgggcgtct
    20881 acgtcctcgt gggccaggtc gccgccgagg tgggcggcgc ggtctggttg cccctggtca
    20941 ccgcccttct gctggcctcc ctcacggccg cgagctacgt cgagctcgtc acgaagtacc
    21001 ccagagccgg cgggtcggcc cactacgcga cccgcgcctt cgggccggcc gcggggtcgc
    21061 tggtggggtt ctgcatggtg gccggcgggg tggtgtcggt ggcggcgctg gcccgcgcgt
    21121 tcgccggtga ctacctcgac gcgctcgtcg ggctgcccac cgtgccggtg gtggtcgtgt
    21181 tcctcgccgc gctggccgcg ctcaacatcc gcggggtgag ggaatcgctg cgcgcgaacg
    21241 ccgtggccac cgtgatcgag gtcggcgggt tggtgctcgt catcgggctc ggtgcgtggg
    21301 tggtgctgcg cggggacgcc gacctgtcgc ggttgtccca ggtggacacc ggtggtggcg
    21361 cggtccaggc ggtcctggcc ggtaccgtgc tcgcctacta ctccttcgtc gggttcgaga
    21421 cgtcggtcaa cctcgccgag gaggtccgcg acccgcgccg gtcctacccc cgggcgttgt
    21481 tcggcgcgct ggccaccgcc ggggcggtgt acctgctggt cggagccgtg accagcgcgg
    21541 tcgtgccgac ggaccggctg gccgcgtcgg acggcccgct gctggaggtg gtgcgcgccg
    21601 cgggcggcgt gccggggtgg ctgttcggcg tgatcgccct ggtcgcggtg gccaacgggg
    21661 cgctgctgac cgggatcatg tcctcccggc tggcctacgg catggcccgg gacgggctgc
    21721 tgccgaccgc cctgacccgg gtcctgccgg gccgccgcac gccgtgggtc gcggtgctgg
    21781 tcacctcggc ggcgtcgctg gtgctcgcgc tcaccggcga ggtcgcggcg ctggcggaaa
    21841 ccctcgtgct cctgctcctg gtcgtgttca ccgcggtcaa cgccgccgtg ctcgtgctgc
    21901 ggcgggacga gggcgaggtc gaccacttcc gggtgcccgt cgtcgtcccg tgcctggccc
    21961 tggcgtcgtg cctgctgctg ttcacccagg tcgacggcga ggtgtggctg cgcggcctgc
    22021 tcctggtcgg actcggcgcg gtgctcgccg cggcgaacca cttccggcgg cgcactgcat
    22081 gactccccgt gctcgccccc ggttatcgaa gggatccggg ggtacacggt ggtgacaacg
    22141 cgaaaggggt tcgccgatgc cagtactcac ccggctcctg ggcgtcgcca cggcggcgta
    22201 cggggccgcg atcgtcgcgg agccgaagtt cctcgcccgg ccgtgcggct tggcggacgc
    22261 gcacggcaac gtcgctcccg ccgtgcggac gatggtcggc gggatcgggg cgcgggacct
    22321 cgccatcggc gcggcgatgg tgttcgcgcc ggccgggacg ccgacccgcg tggcggtcgc
    22381 cgcacgggtg gcgtccgacc tggccgacgc cctggtgttc ggcttgacgc tgcccgaccg
    22441 ggccgcacgg cccaaggtcg cggctttcgc ggtgacctgg gccgtcgcgt gcgcggtgtc
    22501 cgcgttcggg aagaagtgag gtgacgagac cggcggtgct cggttcagcg ggttcccgct
    22561 cgtggccggc acgccggccc gaccgctgaa ccgagcgctc agccggtcac tggaccgagt
    22621 gctcggcgac gtcgaggagg tggacgtcgc gccacggccg cgtcccccgc ccggagccgg
    22681 catacggcgc cagccgtacc gccagatcgc ccttgctcca cccgtccgcc gcggttcgcg
    22741 ttccggtcgt cggctgaccg tcgaacacct ggcgcaccca ccgggccacc gccgccggcg
    22801 ggggcacccg gtccgcgccg aacctggcct ggacgatcag gtcttcgcca ctgtgcgtct
    22861 ccagcgccac ggcccacccg gcggtctcgt cccagacgag cgccacgtca cggtcggggt
    22921 agcccgggag tcggccgtcc agcgccacgt acacgctcct cggaggttcc acctgcacgt
    22981 acgaactctc gccggacagc cgcagctcgt cggcgaccag ccggacgtag ctctgtagcg
    23041 ctcgcaccac ggagtcgtcg aagtcccatt ccacccgcat cgcccgcttc cctctcgcaa
    23101 ccgatgcgcc gactgtttga cgccctgacc gcatacccaa tggggtgaaa caccaaaccc
    23161 ggccggtaac gccgaattca cctgcgcttt cgtgcggtgt gccgccaccc cccgtacccc
    23221 aggcacccgg acgccgagcg aacgggagtc ggagccgcac gcgtccgacc ggcgggttat
    23281 caccgcaccc tgacgacccg cgcgatgtca cccgaacggg tcagtcggat tgcgatggac
    23341 caccgtcggc tactcctcga tcatggatca cagcgaagtg cccgtgctcg acgcgttgca
    23401 ggacttccgc gaccacggct acacgccgtt caacccgccc ggccaccgcc aaggccgcgg
    23461 tgtggacccc agggtgctcg acgtcctggg ccgggacctc ttcgccgcgg acgtcatcac
    23521 acccaacggc ctggacgacc gccgcaccac cggccgcgtg ctggaacgcg cccaggagct
    23581 gatggccgac gcggtgaacg ccgaccacgc gttcttctcg acctgcggca gctcactgtc
    23641 ggtcaagagc gccatgctgg ccgtcgccgg gccgcacgag aagctcatcg tgccccgtca
    23701 cgcgcacaag tcggtcatct cggcgctgat cctcagcggc gtctgcccgg tgtggatcgc
    23761 accgcactgg gacgccgagc ggcacctcgc gcacccgccc ggccccgacg aggtgcgggc
    23821 gctgttccgg gccgagccgg aggccaaggg gatgctgctg gtcaccccca ccgactacgg
    23881 cacctgcggc gacatccgcg cggtggccga ggcgtgccac gagttcggca aacccctgat
    23941 cgtggacgag gcgtggggcg cgcacctgcc gttccacccc gacctgccgc cgtgggccat
    24001 ggacgccgac gccgacctgt gcgtgaccag cgtgcacaag tcgggtgcgg ccgtggagca
    24061 gagttccgtg ttccacctcc aaggcgaccg ggtcgacccc gccgcgctca aggcgcggga
    24121 agacctcctg ggcaccacca gcgccacgtc gctggtgtac gcgagcctgg acggctggcg
    24181 acgccagatg gtccagcacg gcaaggcgct gctgacctcg gacctcgccc tggcccgcac
    24241 cacccgcgcg agcctcgacg agctgccggg cctgcgggtc atgggcgaag ccgagttcac
    24301 cgggccctcc ctcgccgact cgctcgaccc gctcaagctc gtggtggacg tgtccggcct
    24361 ggacatcagc ggctaccagg ccgccgactg gctgcgcgag caccgccgcg tcaccgtcgg
    24421 gctctccgac caccgccgga tcgtcgcgca cttcacccac gccgacgacg agcggtccgc
    24481 cggcgtgctc gtggacgcgc tgcgcgcgct gacccgcgac gccggatcgc tgccgacccc
    24541 gaaaccggtc gacctgcctt caccgcgcga gctgcaactg gagaccgcca tgctgccgcg
    24601 cgacgcgttc ttcgccaccg tcgaacaggt ccccgccgac caggccgtcg gccggatcgc
    24661 cgccgagatg atcaccccct acccgccggg cgcgcccgcc gtgctgcccg gcgaggtcat
    24721 cacccgggag atcctcgact acgtccgcag cggcctggcc gccggcatgg tgctgcccga
    24781 ccccgccgac cctgatctgg agtcggtccg cgtggtggcc cgctgacccg ccagaacgtc
    24841 gagcaccgga acgcccagcg gtacgcgctc acccggcgaa tgagcggggc gcggccgggt
    24901 atccccggtt acccagtgcg gagtggagtg aggccgatgc cgaagcaact gtcggaacag
    24961 gtcgtggtcg tggtcggggc ttcgtcgggc atcgggcggg ccaccgccct gcggctcgcc
    25021 gcacgcggcg cgcgggtcgt gtgcgccgcg cggaacctcc cggcgttgga caccctggtc
    25081 gcgcagatcg gggaacgggc gatggcggtg cggaccgaca tcaccgacga ggccgcggtc
    25141 cacgccctgg cgcgcgccgc cgaacagcgg ttcgggcgga tcgacacgtg ggtcaacgtg
    25201 gccggggtgg gcgtggtcgg ccgggtcgag gacgtgcccg ccgccgagtt cgaccgggtc
    25261 atgagggtga acttcctcgg tcacgtccac ggcgtgcagg cggccctgcc cgccctgcgc
    25321 cgagccggcg gcggggcggt catcggcatc tcctccgtgg agggcgtgcg gtcggtgccg
    25381 tggcaggccc cgtacgcggc gagcaagttc gccctgcgcg cgctctacga cagcctgcgg
    25441 gtggaactgg cccagaccgg cgacccgatc acggtcacca ccatcctgcc cgccgcggtc
    25501 gacacgccgt tcttcgagca ctcccgcacc cacctgggcg tgctgcccaa gccgccggcg
    25561 cccgtgtacg cgcccgagct cgtcgccgac gccgtggcga cggccgccga acacccgcga
    25621 cgcgagatcc cggtaggcgg cgcggcggcg gtgttcttcc tcggccaacg cctgttcccc
    25681 gcgatgaccg acgcgctgat gtcggtgcgc gcactggccg agcacctgtc ccgcaagagc
    25741 ggcccggaca acgaggtgga caacctccac acgaccgtcg ccgggcccgg acgcatccgg
    25801 gggtcgtacc ccggtcgggt gatgcggcgc agcctgttca ccacgctcgc gtcccgcctg
    25861 ccccgaccgg gtgaaatcct cgccgccgcg gtctcccggt cgaacgggtc gaacgggtcg
    25921 aacgggaggt gaccgcgctg ccgagcccgc gtcacgtcac ggcttcagca gcaccttgac
    25981 cgcgttgtcg cgcttctgct ggaagatctc gtacgcgtgc ggcgcttcgg cgagcggcag
    26041 gtggtgcgtg gcgaagtcct cggtgcccaa cgggtcgtcg tcggtgagca gcggcaggat
    26101 ctccggcacc caccgcagca cgttcgcctg ccccatgcgc agctgcacct gcttgtcgaa
    26161 catcttc
//
