LOCUS       NC_019673              22844 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Saccharothrix espanaensis DSM 44229, complete sequence.
ACCESSION   NC_019673
VERSION     NC_019673.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Saccharothrix espanaensis DSM 44229
  ORGANISM  Saccharothrix espanaensis DSM 44229
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Saccharothrix.
REFERENCE   1
  AUTHORS   Strobel,T., Al-Dilaimi,A., Blom,J., Gessner,A., Kalinowski,J.,
            Luzhetska,M., Puhler,A., Szczepanowski,R., Bechthold,A. and
            Ruckert,C.
  TITLE     Complete genome sequence of Saccharothrix espanaensis DSM 44229(T)
            and comparison to the other completely sequenced Pseudonocardiaceae
  JOURNAL   BMC Genomics 13, 465 (2012)
   PUBMED   22958348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9360653)
  AUTHORS   Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2012) IGS, CeBiTec, Bielefeld University,
            Universitaetsstr. 27, D-33335, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000328705.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:06:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,451
            Genes (coding)                    :: 8,313
            CDSs (with protein)               :: 8,313
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 43 of 138
            Pseudo Genes (incomplete)         :: 116 of 138
            Pseudo Genes (internal stop)      :: 7 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:45:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4520675
            Orig. end                         :: 4543519
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE804045.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22844
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="18"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22844
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22844
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12844](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12844
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            105..1085
                     /locus_tag="BN6_RS19950"
                     /old_locus_tag="BN6_41210"
     CDS             105..1085
                     /codon_start=1
                     /function="Threonine dehydrogenase and related Zn-dependent
                     dehydrogenases"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101520.1"
                     /locus_tag="BN6_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41210"
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="WP_015101520.1"
                     /transl_table=11
                     /translation="MTRAARALWFTSAGKCSIRSGPLPDPGPGEVLVRTLHTAVSRGTE
                     TLVLNGSVPANQHSAMRAPFQEGGFPFPVKYGYLNVGVVEQGPAALLGRTVFCLYPHQT
                     RYVVPDHAVTPVPDAVPAQRAVLAGTVETAVNALWDARPMVGDRIAVVGGGMVGCSVAA
                     LLARLPGARVQLVDVDPARRTTAAALGVDFATPEEATGGLDLVVHASASEAGLETSLGL
                     LRPEGVVLELSWYGARRVGVALGEHFHSRRLSVRASQVGVVGRPDRTHAERLALALDLL
                     ADPAFDALITGASPFDDLPAVLPRLASGDLAALCHRIDYGHAHDR"
     misc_feature    complement(152..165)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            1075..1764
                     /locus_tag="BN6_RS19955"
                     /old_locus_tag="BN6_41220"
     CDS             1075..1764
                     /codon_start=1
                     /function="Uncharacterized protein, putative amidase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101521.1"
                     /locus_tag="BN6_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41220"
                     /product="creatininase family protein"
                     /protein_id="WP_015101521.1"
                     /transl_table=11
                     /translation="MTGDPLPRATTADVRERGARVAVLPVGSFEQHGPHLPLVTDTVVA
                     CAIAERIAAEHPVLLLPPITISCSHEHAAWPGTVSISARTLYAVVTDIAESLRRSGVPK
                     LVLVNAHGGNYVLSNVVQEAEGLALFPERSDWHAARAAAGLATSGQSDMHAGELETSIL
                     LHVRPDLVGPDRVDHLAEDRPHLLTHGLHRYSGSGVVGRPSLASADKGRHLLDSLAGSF
                     AGHLAAL"
     gene            complement(1693..2661)
                     /locus_tag="BN6_RS19960"
                     /old_locus_tag="BN6_41230"
     CDS             complement(1693..2661)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101522.1"
                     /locus_tag="BN6_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41230"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_015101522.1"
                     /transl_table=11
                     /translation="MTRVWPWLRLVAAVGILVVLGWRLGSAAFLDGLRAVDPWSVVAAL
                     GIGLLTTVCGAWRWCVVARGLGLPLTLGSAVSDYYRSLLLNAVLPAGVLGDVHRAVSHG
                     QQSGDVGRGVRAVVFERFAGQVVLVLVAVAVLVARPVAVDVRPGVVVSAVAVLVVGAVV
                     GAVAGTVVASRVPKVRAVLGRTFSDARRALLTRYALPRVAALSAVAVAGHVALFVVAAR
                     AAGSTAPLGRLVPLVVLALLVMAVPVNIGGFGPREAFLAVAFGAAGLGAAQGVTTAVVY
                     GVLALVAALPGVLTLVPGSQRRQVARERAGQAVQQVPALVG"
     gene            complement(2684..3460)
                     /locus_tag="BN6_RS19965"
                     /old_locus_tag="BN6_41240"
     CDS             complement(2684..3460)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101523.1"
                     /locus_tag="BN6_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41240"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_015101523.1"
                     /transl_table=11
                     /translation="MTSPGFAPEWLALREPADAAARSAELADRAREIVLNRNPVLVRDL
                     GCGTGSMGRWLSARLAGAQHWVLHDRDPRLLAVAGATVTGPGVTARTVAGDLGALRAAD
                     LAGASLVTASALLDVLTREQVNGLAAACVGAGVPALLTLTVTGRVEFDPAEPLDARLRD
                     AFNDHQRRDGLLGPGAAAAAEEAFTALGARVETRPSPWRLGPDQAALTAEWLRGWVGAA
                     VEQDPALAADAPDYLRRRLAGGLRTVVHHTDLLAVP"
     gene            complement(3457..4452)
                     /locus_tag="BN6_RS19970"
                     /old_locus_tag="BN6_41250"
     CDS             complement(3457..4452)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Glycosyltransferase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101524.1"
                     /locus_tag="BN6_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41250"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_015101524.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.5e-22,
                     bitscore: 79.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGHFVVPDSRTPSGGNTYNRRAGGGLRPVVVAGAWPRPDDAARA
                     ALHRALAGLPDGAPVLLDGLVACGVPEVVTPHADRLRLAVLVHLPLAEETGLDPAVAAE
                     LDAAERACLRAVHAVVATGAAAGERLAAHHGLGRVHVVAPGVDPAPLAPGGDGVSSLLC
                     VASITPRKGHDVLVEALARVADRPWTCVCAGPADPGHARSVRAAIARHGLAERIDLVGP
                     LLGADLDAAYAAADLFVLPSRAETYGMAVAEALARGIPVLASAVPDALGDGGWLLPGDA
                     ASLADALRRWFDSARTRAGLRDAARARRRELSTWEETVLGLAAVLASLRT"
     gene            complement(4449..4847)
                     /locus_tag="BN6_RS19975"
                     /old_locus_tag="BN6_41260"
     CDS             complement(4449..4847)
                     /EC_number="4.1.2.50"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTPS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016331711.1"
                     /locus_tag="BN6_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41260"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_041317455.1"
                     /sec_met_domain="PTPS (E-value: 2e-23, bitscore: 81.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSITVRDHVMVAHSFSGEVFGPAQRLHGATFVVDARFKRVELDQ
                     DNIVVDIGLATQELRAVLADLNYRNLDEVPEFAGINTSTEFLAKHIADRLADRVRAGAL
                     GVGAHGLSGIEVSLHESHVAWASYERDL"
     gene            4940..5584
                     /gene="ribA"
                     /locus_tag="BN6_RS19980"
                     /old_locus_tag="BN6_41270"
     CDS             4940..5584
                     /EC_number="3.5.4.25"
                     /GO_function="GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="GTP cyclohydrolase II"
                     /gene="ribA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101526.1"
                     /locus_tag="BN6_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41270"
                     /product="GTP cyclohydrolase II"
                     /protein_id="WP_015101526.1"
                     /transl_table=11
                     /translation="MHERVFGEAEVAESDLVTRRGTFRAVAFRADGHEHLALVLGRVRL
                     RADVLVRVHSECMTGDIFGALRCECGEQLDAAMDAVVREGSGVLVYLRGHEGRGIGLVE
                     KVRTHVLQDERGLDTIDSATELGLPVDVRDYRPAALVLRHLRVRSVRLLSNNPDKIQAL
                     EDNGIPVTARVPLLMAPNEHNLGYLTAKRDRLGHDLPQVAGHQDLLRAVDG"
     gene            complement(5637..6404)
                     /gene="atpB"
                     /locus_tag="BN6_RS19985"
                     /old_locus_tag="BN6_41280"
     CDS             complement(5637..6404)
                     /EC_number="7.1.2.2"
                     /GO_component="GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA]"
                     /GO_function="GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA]"
                     /GO_process="GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /function="F0F1-type ATP synthase, subunit a"
                     /gene="atpB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101527.1"
                     /locus_tag="BN6_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41280"
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="WP_015101527.1"
                     /transl_table=11
                     /translation="MADNTFTPPGARDLFPPEIVGWVTKPMILVVLSTFIIAGFFLITA
                     RRLTIVPNRLQFAAETIYDFGRNTIAREQIGGKDFAPYVPFILSLFTFVLVNNIFGIIP
                     LIQFPTMAHIGFPAALAILLVFPTYHVVGIRRHGLRGYLRNQFSYPGVPKPVLWFLLIP
                     TEIILKFFFDPVTLAIRVFAAMFAGHLLVVVFVLGGEFLLLHAGPLVKPVSLLSFALAI
                     AITLLEALIQVLQAYIFATLSAHYIGRALAADH"
     gene            6626..8071
                     /locus_tag="BN6_RS19990"
                     /old_locus_tag="BN6_41290"
     CDS             6626..8071
                     /codon_start=1
                     /function="Coenzyme F390 synthetase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101528.1"
                     /locus_tag="BN6_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41290"
                     /product="phenylacetate--CoA ligase family protein"
                     /protein_id="WP_015101528.1"
                     /transl_table=11
                     /translation="MDADRPGRVAEGFRSFFADDRVPESVLELFHRVAATVPAYRKFLA
                     EHGVDPERVVTLDDFRRLPPTDKDNYHRRYPLPELCRDGRLDGCDLVAVSSGSSGRPTA
                     WPRSLVDELAITRRFEQVFRDAFRAHERSTLAVVCFPLGTWVGGLFTTACVRHLAAKGY
                     PITAVAPGNNKAEILRVLPELAGHFEQVVLMGYPPFVKDVVDSAHFDPAGFDWAAHDVK
                     LVLAGEVFSEQWRTLVAGRLGIADPVRATASLYGTADAGVLGNETPLSVSVRRFLAGRP
                     DLARELFGGSRLPTLVQYDPASRFFEEADGTLLFSGDNGIPLIRYHIADEGGLVSSVDM
                     REFLARNGCTIPFDNELPFVFVFGRSLFTVSYFGANVYPENVSVGLEQPGVSDLVTGKF
                     VLEAVSDADEDAALRVTVELAPGRTGDPGVIAESIRAHLVRLNSEFAHYVPAERQLPQV
                     VLRPAGDPEHFPVGVKHRYTRAR"
     gene            8162..8671
                     /locus_tag="BN6_RS19995"
                     /old_locus_tag="BN6_41300"
     CDS             8162..8671
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /function="Histone acetyltransferase HPA2 and related
                     acetyltransferases"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101529.1"
                     /locus_tag="BN6_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41300"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_015101529.1"
                     /transl_table=11
                     /translation="MEIRRGGPADLAVLLAMLDGAVAWLDASGRTGQWGSRPWSADQKR
                     AGRVADRVREDVVWVAEVDGEPAGVLTHSGRAPEYVPAADEPELYVRILVTSRAFTGRG
                     VGGALLDHARDQARAQGVGLVRVDCYAGGDGQLVRYYERSGFTAVEKFTVEDWPGQLLA
                     DRVTAS"
     gene            8969..9718
                     /locus_tag="BN6_RS20000"
                     /old_locus_tag="BN6_41310"
     CDS             8969..9718
                     /codon_start=1
                     /function="DNA-binding transcriptional activator of the
                     SARP family"
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015649.5"
                     /locus_tag="BN6_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41310"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_015101530.1"
                     /transl_table=11
                     /translation="MAVLVLGRPAVRVGGVVRHPARRMVRILLGVLAVRANRALPLEWI
                     IDALWPVRPPASAAANVRNHLAELRRLLGEVDPDGPGIVTSRTGYVLAADPDVVDVTQF
                     QALLAEGRELRACGADAAAARCLTRAVGLWRGPVMAGAPVPDVVRPDVTVLDEQRLCAI
                     EDLAEVRLALGCAFDLVPALAGLVVEHPLRERLWRNLVGALAAAGRRTEALAVYHRLVR
                     VLDSELGVAPSAATAELYEAVRRDRRD"
     gene            9802..9993
                     /locus_tag="BN6_RS20005"
                     /old_locus_tag="BN6_41320"
     CDS             9802..9993
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040361.4"
                     /locus_tag="BN6_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41320"
                     /product="DUF6229 family protein"
                     /protein_id="WP_015101531.1"
                     /transl_table=11
                     /translation="MTAALLLDAEEMVARWRAGLDESDNPAGPLFANGEFAEGDIVACN
                     PPGSRCSSCTASRPVYCC"
     gene            10001..12844
                     /locus_tag="BN6_RS20010"
                     /old_locus_tag="BN6_41330"
     CDS             10001..12844
                     /codon_start=1
                     /function="Lantibiotic modifying enzyme"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="BN6_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41330"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_015101532.1"
                     /sec_met_domain="DUF4135 (E-value: 8.7e-72, bitscore:
                     241.3, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-28, bitscore:
                     98.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRDEVGELDRTLEWLLGPATDRLSRRLAEVAGLGAPEARALLDA
                     AREVLLDVVRRKVIRVLVLELNAARVTGALTADDPAGRWAQFLAHAAEESYWHGLTRHY
                     PHLVGRLRATVENRVAAIATLAGRFAEDRPRLAALLGADAGELRKVEFGAGDSHRGGHS
                     VTLVHCTGGTVVYKPRPMEVDQRLAGLLAVLTAGDRYPIRVPAAVVRDGYGWAGHVDHR
                     YCATEDELAAFYTALGHWLAVMRLVSGTDLHAENIIACGPVPVVVDCESVFTPRPPHPP
                     TGAGEATDRVAEQLNRTVLRTGLLPGRGAGLGWRGVDGSAMGGLPGEQPDIGLPDLVGA
                     GTDTARVAIVPQQLPPTRNLPSPHPRLAHHWPRVVAGFDAMAERITRLDRAGALEPLLA
                     GFADCVVRVIVRDTESYTELARMLWHPAGLHDQAAAEGRARALLARHSMNTRGPGDPDV
                     HAAEVAELLVGDIPVFTTTPAEGWLHTPGGLVCGPRVDQVALALENWRTADLGLERRVT
                     HAALVSAYLNQGAEPELGRLPAPPPDRTGLDRRRRALAAGLVRELAGEAVRGADGTATW
                     FAPILDRSGWQTTPLTPDLYGGTLGVAVLLAGYRHEVAAGRADAVDGVAELLAGTVRTA
                     RLTQRWWAEQAEHTRRRPDPTGGYIGLGSQIWCWLALDRLGLAADDEGDPVPDALFLAR
                     QLPAAIAASEGPDLVVGTAGAIVPLLLLAERTGDDQWVDLAAHAGRALVADAVVTGGRA
                     HWPAPNWPGGIGGFAHGATGIGWALGRLAEVTGERRFADLARGAAAYEETWYSAERGAW
                     MDPREPDTVAAAWCHGAIGVGLATDDPEVLRRAASSALRDGIGWTHTLCHGDLGTWELL
                     TAALAAGVAPDGLDRAGLDAMVLGSLEANGPTTGLAREVYSPSIMSGSGGIAYQLLRMH
                     PDSDLPSVLLLGDGPAR"
     misc_feature    10038..10053
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            12841..14766
                     /locus_tag="BN6_RS20015"
                     /old_locus_tag="BN6_41340"
     CDS             12841..14766
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="ABC-type multidrug transport system, ATPase and
                     permease components"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101533.1"
                     /locus_tag="BN6_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41340"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_015101533.1"
                     /transl_table=11
                     /translation="MTGEPDPREGALVTPHWQLDDADRAPRRTLRGLPSATWPVLAMIR
                     RAAPGPALAVVVMQVVSGLAAAFGLFATTGVLTELLASGAAGDRIVAALPQLVLVGAAF
                     GLRGAMDVGVALAHARITPAVRRLAEERLYSASLGADLASFDDSRFYDRMHRARDRGLF
                     FLERAADNLVELIGSLLGIAAAAGSLVVLHPALLPVLLLAVIPDGWAVQRAARLAYASV
                     GRTVALDRRVQMVSDLATEREPAAEIRAYRAEPFVLHEYRVAADPLRDEEVRLATAQAR
                     VRGIGRALAGVGLAVTYVVLGLLVRYGWVPLAVAGTAVIAIRVATTALNRLVLAANQLV
                     EQGMYVADYQDFLAAVPDSSAPDSAAPDPSAPDSAAGKPPGAGPPPLDPGRVVLDHVTF
                     SYPESARTAVRDVTLTIEPGETVALVGENGSGKTTLAKLIAGLYPPTSGRVRWGGRDLA
                     DVDRRQAADRVMMVLQDPIRWPHTARVNVRVGRHERPDPAGAAVRSAAGQSGADEVVAG
                     LPDEWETLLSKQFRGGVELSGGQWQRLAVARGLYRDAPLLIWDEPTAPLDAKAEFAVYE
                     SLRALAADRTVVLITHRLASVRHADRILLLHEGELVEQGTHAALLAAGGRYAELYELQS
                     RMYADA"
     gene            14759..16084
                     /locus_tag="BN6_RS20020"
                     /old_locus_tag="BN6_41350"
     CDS             14759..16084
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.5"
                     /locus_tag="BN6_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41350"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_051075654.1"
                     /transl_table=11
                     /translation="MLDLVTPRDERYALSRTQFIGRPVEVLPRAVARCGSAGEVVEALA
                     FARSRGLPFAIRGGGHSNACHSSTSGLLVDVTPADRITVADGLVTVGGGVRIGRLARAL
                     APLGRLVPTGSCPSVGVVGAALGGGFGSHGRLHGLTCDALVGAEVVLADGRVVGTAGEP
                     DLLWALRGAGGGLGVVTSATFRTVAALPRTHFRLEWGFEHAAALVAWWQRWAPGAPDGV
                     SAELVLLGPQYPEEPPVALLIGAAPDRAAVQAFADDFGRPAVAEIADLSAADAALLHAT
                     PYSAVAHDPSEIPLVHDRPGLSTATTGFFARPLPDDAVAALLAHFTADRVMGELREVAF
                     TPWGGGYARTPGDATAFGHRDPAFLVKHTVLVGPGGAARRGEVVLARARAGRDLLRPWG
                     TGGAYVNFPEPGLPDHAYHGANAARVRAVKAHYDPGGAFRPG"
     gene            complement(16144..17007)
                     /locus_tag="BN6_RS20025"
                     /old_locus_tag="BN6_41360"
     CDS             complement(16144..17007)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (90-241). E-value: 3.3e-10. Score:
                     30.5. Matches aSDomain: nrpspksdomains_BN6_RS20025_oMT.1"
                     /codon_start=1
                     /function="SAM-dependent methyltransferases"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015101535.1"
                     /locus_tag="BN6_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41360"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_015101535.1"
                     /transl_table=11
                     /translation="MTTVAPGVLRTDYQRSVAAYWNAERDPVNIRLGEVDGIYHHHYGI
                     GPYDESVLVGPEETRDARVIAELHRLETAQADFLIDRFAGTGPQDRLLDGGSGRGGTSI
                     MTNRRYGCRVDGVSISEKQVEFANNQAAKWGVADQVRFHFRNMLDTGFETGAFRGVWTN
                     ETTMYVDLFDLFGEFSRLVAPGGRYVCITGCYNDLTGGRSKAVSQIDERYTCSVHPRSA
                     YFKAMAANNLVPIEVVDLTPHTIPYWELRERSSVATGVESSFLTAYREGSFHYLMIVAD
                     RVPGRR"
     aSDomain        complement(16285..16737)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BN6_RS20025_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.30E-10"
                     /label="BN6_RS20025_oMT.1"
                     /locus_tag="BN6_RS20025"
                     /protein_end="241"
                     /protein_start="90"
                     /score="30.5"
                     /tool="antismash"
                     /translation="RLLDGGSGRGGTSIMTNRRYGCRVDGVSISEKQVEFANNQAAKWG
                     VADQVRFHFRNMLDTGFETGAFRGVWTNETTMYVDLFDLFGEFSRLVAPGGRYVCITGC
                     YNDLTGGRSKAVSQIDERYTCSVHPRSAYFKAMAANNLVPIEVVDLT"
     misc_feature    17120..17140
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     CDS             complement(17124..17213)
                     /gene="allorf_4537799_4537888"
                     /locus_tag="allorf_4537799_4537888"
                     /protein_id="allorf_4537799_4537888"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPARRPEQAAGSAHRLTHSGDCTRSNSRC"
     CDS_motif       complement(17178..17213)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPARRPEQAAGS"
                     /locus_tag="allorf_4537799_4537888_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17124..17177)
                     /prepeptide="core"
                     /locus_tag="allorf_4537799_4537888_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="1811.0"
                     /monoisotopic_mass="1809.9"
                     /core_sequence="AHRLTHSGDCTRSNSRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPARRPEQAAGS"
                     /leader_location="[17177:17213](-)"
                     /alternative_weights="1829.0"
                     /alternative_weights="1847.0"
                     /alternative_weights="1865.0"
     CDS             complement(17226..17393)
                     /gene="allorf_4537901_4538068"
                     /locus_tag="allorf_4537901_4538068"
                     /protein_id="allorf_4537901_4538068"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLPAPATPSRGRYSWSPPARPSGRHRARSAAAAASRGPPGPGRT
                     NTVRPRNAAC"
     CDS_motif       complement(17292..17393)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLPAPATPSRGRYSWSPPARPSGRHRARSAAAA"
                     /locus_tag="allorf_4537901_4538068_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17226..17291)
                     /prepeptide="core"
                     /locus_tag="allorf_4537901_4538068_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="2081.3"
                     /monoisotopic_mass="2080.1"
                     /core_sequence="ASRGPPGPGRTNTVRPRNAAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLPAPATPSRGRYSWSPPARPSGRHRARSAAAA"
                     /leader_location="[17291:17393](-)"
                     /alternative_weights="2099.3"
                     /alternative_weights="2117.4"
     gene            complement(17438..18271)
                     /locus_tag="BN6_RS20030"
                     /old_locus_tag="BN6_41370"
     CDS             complement(17438..18271)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009085307.1"
                     /locus_tag="BN6_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_41370"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_041313365.1"
                     /transl_table=11
                     /translation="MTIISALGALTAGERDRAREFAARVGSPLGTALAEYLGSDADGTV
                     YDRPAAFQAFIDGGGNVGLYEAVSGALTALYDRVRPGALLDVGCGDGRALVPALAGHRP
                     RVTVVEPSTALLRTAVERLPDGLVVDARNTGVEEFVTGPGRHDVAQSTFALHALPHDVR
                     DAVLAALAPHVGTLAVVEFDVPDLSPQRRLEFLAETYERGLAKYDDDRDLVAQGFLMPV
                     LTGQLLPGAVRSTWEQPAAAWVAQVTRAGFADVEITPLFDYWSSPAFLLTATGSA"
     misc_feature    complement(18256..18270)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.48"
                     /tool="antismash"
     gene            18403..19368
                     /locus_tag="BN6_RS20035"
                     /old_locus_tag="BN6_41380"
     CDS             18403..19368
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BN6_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BN6_41380"
                     /product="hypothetical protein"
                     /protein_id="WP_015101537.1"
                     /transl_table=11
                     /translation="MARVRLVPGGREVDLDCLSAADRCAIVALRGEVRRGDRVLLCLEQ
                     PEDDELFVREVDGRYFASHFAGGRPGSHGAHEIVAETDEHQRQREYWYRAGQDAEFSSE
                     RSFRTSAGNVLDVAIHGRTRTGVQLEHSRLTAAVAHQRTTRAGRAGWLSLWFTAADRVP
                     KWFHRVPSVGCNHIAWDALPPRGTAQATGLKKVQAVKCTVHDFGGKCPAGKHRPCGRFH
                     PQFVAWHQVTLDKVAYFVPSGRAVPLLTPRREVVLVPPEGLALYESLTGRSARYAAEKF
                     SHSAVRCEQCDNALLWIRPGRVRCEQCDPIMNLPRSPYPL"
     misc_feature    complement(20520..20535)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.04"
                     /tool="antismash"
     misc_feature    22167..22181
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    22173..22187
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
ORIGIN
        1 acctgcgcgc ccgcccagac ggcgtgttcc ggcacggccg gcgcggcggt gtgctgaagt
       61 gtgatcatcg gtgcccctca tgacccgttt tcggaggttg ccggatgaca cgcgccgcac
      121 gggcactgtg gttcacctcg gccgggaaat gttcgatccg gtccgggccg ctgcccgatc
      181 cagggccggg cgaggtgctg gtgcgcaccc tgcacacggc ggtcagccgg ggcaccgaga
      241 ccctggtcct gaacggctcg gtgcccgcca accagcactc cgcgatgcgc gcgccgttcc
      301 aggagggcgg gttcccgttc ccggtgaagt acgggtacct caacgtcggg gtggtcgagc
      361 agggcccggc cgcgctgctc ggccgcacgg tgttctgcct gtacccgcac cagacccggt
      421 acgtcgtccc ggaccacgcc gtcacgcccg tccccgacgc ggtcccggca cagcgcgccg
      481 tgctcgccgg cacggtggag accgccgtga acgccctgtg ggacgcccgg ccgatggtcg
      541 gcgaccggat cgccgtggtc ggcggcggca tggtcggctg ctcggtggcg gcgctgctgg
      601 cgcggctgcc cggcgcacgg gtccagctgg tcgacgtcga cccggcccgc cgcacgaccg
      661 ccgccgcgct cggcgtggac ttcgcgacgc ccgaggaggc caccggcggg ctggacctgg
      721 tggtgcacgc cagcgcgtcg gaggcgggcc tggagacgtc gctgggcctg ctccggccgg
      781 agggggtggt gctggagctg agctggtacg gcgcgcggcg ggtcggcgtc gcgctgggcg
      841 agcacttcca ctcccgccgg ctgtccgtgc gggccagcca ggtcggcgtg gtcggccgcc
      901 cggaccgcac ccacgccgaa cgcctcgcgc tcgccctgga cctgctcgcc gacccggcgt
      961 tcgacgcgct gatcaccggc gcgagcccgt tcgacgacct gccggccgtg ctgccccggc
     1021 tggcgtcggg cgacctcgcc gcgctgtgcc accggattga ctacggtcac gcccatgacc
     1081 ggtgacccgc tgccccgcgc cacgaccgcc gacgtccggg agcgcggcgc gcgggtcgcc
     1141 gtgctgccgg tgggcagctt cgagcagcac ggcccgcacc tgccgctggt caccgacacc
     1201 gtggtggcct gcgccatcgc cgagcggatc gccgccgagc acccggtgct gctgttgccg
     1261 ccgatcacca tctcctgctc gcacgagcac gccgcgtggc ccggcacggt gagcatctcg
     1321 gcccgcaccc tgtacgccgt ggtcaccgac atcgccgagt cgctgcgccg gtccggcgtg
     1381 ccgaagctgg tgctggtcaa cgcgcacggc ggcaactacg tgctgtcgaa cgtggtgcag
     1441 gaggccgagg gcctggcgct gttcccggag cgctccgact ggcacgccgc ccgcgccgcc
     1501 gccggcctgg cgacctccgg gcagagcgac atgcacgccg gggagctgga gacctcgatc
     1561 ctgctgcacg tccgcccgga cctggtcggt ccggaccggg tcgaccacct ggccgaggac
     1621 cgcccgcacc tgctgaccca cggcctgcac cgctactccg ggtccggcgt ggtgggccgg
     1681 ccgtcgctgg cgtcagccga caagggccgg cacctgctgg acagcctggc cggctcgttc
     1741 gcgggccacc tggcggcgct gtgagccggg aaccagggtg agcacccccg gcagcgcggc
     1801 gaccagcgcc agcaccccgt agaccacggc ggtggtcacg ccctgcgccg cgcccagccc
     1861 ggccgccccg aacgccaccg ccaggaacgc ctcgcgcggc ccgaacccgc cgatgttcac
     1921 cggcaccgcc atcaccagca gcgcgagcac gaccagcggg accagtcggc ccagcggcgc
     1981 ggtcgagccg gccgcccgcg cggcgaccac gaacagcgcg acgtgcccgg ccaccgccac
     2041 cgcggacaga gccgcgaccc ggggcagcgc gtaccgggtg agcagcgcgc ggcgcgcgtc
     2101 ggagaacgtc cggcccagca ccgcgcggac cttcggcacc cggctcgcga ccacagtgcc
     2161 ggccaccgcg ccgaccaccg cgccgaccac caggaccgca acggcggaca ccacgacacc
     2221 gggccggacg tcgaccgcca ccggccgcgc gaccagcacc gcgaccgcga ccagcaccag
     2281 cacgacctgc ccggcgaacc gctcgaacac caccgcccgc acgccccggc cgacatcgcc
     2341 ggactgctgg ccgtgggaga ccgcgcggtg cacgtcgccg agcacgccgg cgggcagcac
     2401 cgcgttgagc agcaggctgc ggtagtagtc ggagacggcg ctgccgagcg tgagcggcag
     2461 gccgagcccg cgcgccacca cgcaccaccg ccacgcgccg cacaccgtgg tcagcagccc
     2521 gatcccgagg gccgcgacca ccgaccacgg gtcgaccgcc cgcagcccgt cgaggaacgc
     2581 cgccgacccc agccgccacc ccagcaccac caggatgccg accgccgcca ccagccgcag
     2641 ccacggccac acccgcgtca cgacgacccc tccggccggg tcgtcacggc accgccagga
     2701 gatcggtgtg gtgcaccacg gtccgcagcc cgccggcgag cctgcgccgc aggtagtcgg
     2761 gcgcgtcggc ggccagcgcc gggtcctgct cgacggccgc gccgacccag ccgcgcagcc
     2821 actcggcggt cagcgcggcc tggtcggggc ccagccgcca cgggctcggc ctggtctcga
     2881 cccgcgcgcc gagcgccgtg aacgcctcct cggcggccgc cgccgcaccg ggcccgagca
     2941 ggccgtcccg gcgctggtgg tcgttgaacg cgtcgcgcag ccgcgcgtcg agcggctcgg
     3001 ccgggtcgaa ctcgacgcga ccggtcacgg tgagggtcag cagagcgggc acacccgctc
     3061 ctacgcacgc cgccgccaac ccgttcacct gctcccgggt cagcacgtcg agcagcgccg
     3121 acgccgtcac cagcgacgcg cccgccaggt cggcggcccg caacgcgccg aggtcgcccg
     3181 ccaccgtccg cgccgtcacg cccggcccgg tcaccgtcgc acccgccacg gccagcagcc
     3241 gggggtcccg gtcgtgcagc acccagtgct gcgcgccggc cagccgcgcg gagagccacc
     3301 gccccatcga tcccgtgcca caccccagat cacggacgag gaccgggttc cggttcagca
     3361 cgatctcgcg ggcccggtcc gccagttcgg cgctgcgcgc ggcggcgtcc gccggttcgc
     3421 gcagggccag ccactccggg gcgaaaccag gggaggtcat gtccgcagac tagccagcac
     3481 cgcggccagc ccgaggaccg tttcctccca cgtggacagc tcgcgccggc gggcgcgggc
     3541 ggcgtcgcgc agcccggcgc gcgtccgggc ggagtcgaac cagcggcgca gcgcgtccgc
     3601 cagcgaggcc gcgtcaccgg gcagcagcca cccgccgtcg cccaaggcgt ccgggactgc
     3661 gctggccagc accgggatcc cgcgcgccag cgcctcggcc accgccatcc cgtaggtctc
     3721 ggcgcgggac ggcagcacga acaggtcggc cgccgcgtag gccgcgtcga ggtccgcccc
     3781 gagcagcggc ccgaccaggt cgatccgctc cgccagaccg tgccgggcga tcgcggcgcg
     3841 caccgaccgg gcgtgcccgg ggtccgccgg cccggcgcag acgcaggtcc acggccggtc
     3901 ggcgacccgg gccaaggcct cgaccagcac gtcgtggccc ttgcgcgggg tgatcgacgc
     3961 gacgcagagc aaactcgaca ccccgtcgcc gccgggggcg agcggcgcgg ggtcgacgcc
     4021 gggcgcgacc acgtgcacgc ggcccagccc gtggtgggcg gccaggcgtt cgcccgccgc
     4081 cgcgccggtc gccacgaccg cgtgcacggc gcgcaggcag gcccgctcgg cggcgtccag
     4141 ttcggccgcc accgccgggt ccaacccggt ctcctcggcc agtggcaggt gcaccagcac
     4201 ggccagccgc agccggtcgg cgtgcggtgt gacgacctcg ggcaccccgc acgccaccag
     4261 cccgtcgagc agcaccggcg cgccgtccgg caggccggcc aacgcccggt gcagcgccgc
     4321 gcgggcggcg tcgtccgggc gtggccaggc accggcgacg acgaccggcc gcagcccgcc
     4381 gccggcccgc cggttgtagg tgttgccgcc gctgggggtc cggctgtccg ggacgacgaa
     4441 gtgcccggtc acaggtcccg ttcgtagctc gcccaggcca cgtgcgactc gtgcagcgag
     4501 acctcgatgc cggacaggcc gtgcgcgccc acgccgagcg cgcccgcgcg cacccggtcc
     4561 gccagccggt cggcgatgtg cttggccagg aactcggtcg aggtgttgat cccggcgaac
     4621 tcgggtacct cgtccaggtt ccggtagttc aggtcggcca gcaccgcgcg caactcctgg
     4681 gtggccagtc cgatgtcgac tacgatgttg tcctggtcca gttcgacccg tttgaaccgg
     4741 gcgtccacga cgaacgttgc tccatgcagg cgttgtgccg gaccgaagac ctcgccgctg
     4801 aagctgtgcg cgaccatcac gtggtcgcgg acggtgatgc tgaacagggt gacctccacg
     4861 gggtgagcga tccgccggtg caacctccga cccgagcgta gccaacgccg ggtcgggagt
     4921 cgggtgatga ggggggcgga tgcacgagcg agtcttcggc gaggccgagg tcgccgagtc
     4981 ggacctggtg acgcggcggg gcacgttccg ggcggtggcg ttccgggcgg acgggcacga
     5041 gcacctggcg ctggtgctcg gccgggtccg gctgcgggcg gacgtgctgg tgcgcgtcca
     5101 ctcggagtgc atgaccggcg acatcttcgg cgcgctgcgc tgcgagtgcg gcgagcagct
     5161 ggacgccgcg atggacgccg tcgtgcgcga gggcagcggt gtcctggtgt acctgcgcgg
     5221 ccacgagggc cggggcatcg gcctggtcga gaaggtccgc actcacgtcc tgcaggacga
     5281 gcgcggcttg gacacgatcg actcggccac cgaactcggc ctgccggtcg acgtccggga
     5341 ctaccggccg gcggcgctgg tgctgcggca cctgcgggtg cggtccgtgc ggctgctgtc
     5401 gaacaacccg gacaagatcc aggcgttgga ggacaacggc atcccggtca ccgcccgggt
     5461 gccgctgctg atggcgccca acgagcacaa cctcggctac ctgacggcca agcgcgaccg
     5521 cctcggccac gacctgccgc aggtcgccgg ccaccaggac ctgctgcgcg ccgtcgacgg
     5581 ctgaacccgc tgaccgctga acccgctgac cccgggcccg ccgaggttcg gcgggttcag
     5641 tggtcagcgg cgagcgcgcg cccgatgtag tgggcgctga gcgtggcgaa gatgtaggcc
     5701 tggagcacct ggatcagcgc ctccagcagg gtgatcgcga tggccagcgc gaaactgagc
     5761 aacgacaccg gtttcaccag tgggccggcg tgcaacagca ggaattcgcc gccgagcacg
     5821 aataccacca ccagcaggtg tccggcgaac atcgccgcga acacccggat ggccagggtc
     5881 accgggtcga agaagaactt caggatgatc tcggtcggga tcagcaggaa ccagagcacc
     5941 ggtttcggca cgcccgggta gctgaactgg ttgcgcaggt agccgcgcag gccgtgccgc
     6001 cggatgccga ccacgtgata ggtggggaag accagcagga tggccagcgc ggccgggaac
     6061 ccgatgtgcg ccatggtcgg gaactggatg agcgggatga tcccgaagat gttgttgacc
     6121 agcacgaacg tgaacagcga caggatgaac ggcacgtacg gcgcgaagtc cttgccgccg
     6181 atctgctcac gcgcgatggt gttgcggccg aagtcgtaga tcgtttcggc ggcgaactgg
     6241 agccggttcg gcacaatcgt cagccggcgc gcggtgatca ggaagaatcc ggcgatgatg
     6301 aaggtcgaca ggacgaccag gatcatcggt ttggtgaccc acccgacgat ttccggcggg
     6361 aacaggtccc gggctccggg tggggtgaag gtgttgtcgg ccatgggcgc cccccgtcca
     6421 aggtcttggt ccggacttta ccggacggtg atccggcgtc cagggcctgc ccggtgattt
     6481 cccggtcggc ggacaagccg ccggaaacgc cctgggcacc ccgccgcccg gccgcccgga
     6541 ccgggtcgtc gcgggtcgtc gcgggtgcgg ttcgccgccg ggcgggtgat cccgcggcgc
     6601 tccccggcgt tctagggttg gcggcatgga cgccgacagg ccgggccggg ttgccgaggg
     6661 gttccggtcg ttcttcgccg acgaccgggt gccggagtcg gtgctggagc tgttccaccg
     6721 ggtcgccgcg accgtgcccg cgtaccggaa gttcttggcg gagcacgggg tcgacccgga
     6781 gcgcgtggtc accctggacg acttccgccg gctgccgccg accgacaagg acaactacca
     6841 ccgccgctac ccgctgccgg agctgtgccg ggacggccgg ctcgacgggt gcgacctggt
     6901 cgcggtgtcg tccgggtcga gcgggcggcc gaccgcgtgg ccgcgttccc tggtcgacga
     6961 actggccatc acccgccggt tcgagcaggt gttccgcgac gcgttccggg cccacgagcg
     7021 cagcacgctg gccgtggtgt gcttcccgct cggcacgtgg gtcggcggcc tgttcacgac
     7081 ggcgtgcgtg cggcacctgg ccgcgaaggg ctacccgatc acggcggtcg cgccgggcaa
     7141 caacaaggcc gagatcctgc gcgtgctgcc ggaactggcc ggccacttcg agcaggtggt
     7201 gctcatgggc tacccgccgt tcgtgaagga cgtggtcgac tcggcgcact tcgacccggc
     7261 ggggttcgac tgggcggcgc acgacgtgaa gctggtgctg gcgggggagg tgttcagcga
     7321 acagtggcgc accctggtgg cggggcggct gggcatcgcc gacccggtgc gcgccacggc
     7381 gtcgctgtac ggcacggcgg acgccggcgt gctgggcaac gagacaccgc tgtcggtgtc
     7441 ggtgcgccgt ttcctggccg gtcgcccgga cctggcgcgc gagctgttcg gcgggtcgcg
     7501 gctgcccacg ctcgtccagt acgacccggc gagccggttc ttcgaggaag ccgacgggac
     7561 gctgctgttc tccggcgaca acggcatacc gctgatccgc taccacatcg ccgacgaggg
     7621 cggcctggtg tcctcagtgg acatgcggga gttcctggcg cgcaacgggt gcacgatccc
     7681 gttcgacaac gaactgccgt tcgtcttcgt gttcgggcgg tcgctgttca cggtctcgta
     7741 cttcggggcg aacgtgtacc cggagaacgt ctcggtcggt ctggagcagc ccggcgtcag
     7801 cgacctggtg accgggaagt tcgtgctgga ggcggtgtcc gacgcggacg aggacgccgc
     7861 gctgcgggtc accgtcgagc tggcacccgg ccgcaccggg gaccccggtg tcatcgcgga
     7921 gtcgatccgc gcgcacctgg tgcggctcaa cagcgagttc gcgcactacg tcccggccga
     7981 acggcaactg ccgcaggtgg tcctgcgccc cgccggcgac ccggagcact tcccggtcgg
     8041 ggtgaagcac cgctacaccc gtgcccgctg agcgccggcg gccgtccaca gtggccgggg
     8101 cgttccggtc tcccggtcga cgtagagtcg gggcctgact gttcgagcgc agggggacgt
     8161 ggtggagatc cgtcgtggtg ggccggccga cctggccgtg ctgttggcga tgctggacgg
     8221 cgcggtggcg tggctggacg cctccgggcg caccggccag tggggcagcc ggccgtggtc
     8281 ggcggaccag aagcgggccg ggcgggtcgc cgaccgggtc cgcgaggacg tggtgtgggt
     8341 ggccgaggtc gacggcgagc cggccggcgt cctgacccac tcggggcggg ccccggagta
     8401 cgtgcccgcc gccgacgagc ccgagctgta cgtgcggatc ctggtcacct cgcgcgcgtt
     8461 caccggacgc ggggtgggcg gcgcgctgct cgaccacgcc cgcgaccagg cccgagcaca
     8521 gggcgtcggc ctggtccggg tcgactgcta cgcgggcggc gacggccagt tggtccgcta
     8581 ctacgagcgc agcggtttca cggcggtcga gaagttcacg gtcgaggact ggccggggca
     8641 gctcctggcc gaccgggtca ccgcttcctg agccgccgcc cccggtcctg gtcggcgaat
     8701 cccgttgcgg tcacgggaaa accgatccag agcgacgccc cgtgatggtc cggaaccggt
     8761 gcgtagtcgg gctgggtccg ttgggggaca ccggtttcac cccgcgctga tcgcccggac
     8821 gaggtcgggg ttgagccggt tgggtgcgcg ccgcgcgggt tgtgcttcgt cagaccgcag
     8881 caacccgggc ccgccccgtt cccgtccgca cccgtggcgc gcatcgtcgc aggaccgaag
     8941 tcccggcggg cgaggggagt gggtcggcat ggcggttctg gtgctgggac ggccggcggt
     9001 ccgggtcggc ggggtggtcc gccacccggc gcggcggatg gtgcggatcc tgctgggcgt
     9061 gctggcggtg cgggccaacc gggcgctgcc gctggagtgg atcatcgacg ccctgtggcc
     9121 ggtccggccg cccgcgtcgg ccgccgcgaa cgtgcgcaac cacctcgcgg agctgcgccg
     9181 gctgctgggc gaggtcgacc cggacgggcc gggcatcgtc acctcgcgca ccgggtacgt
     9241 cctcgccgcc gacccggacg tggtggacgt gacgcagttc caggcgctcc tcgccgaagg
     9301 ccgcgagctg cgcgcgtgcg gcgcggacgc ggcggcggcg cgctgcctga cccgcgcggt
     9361 gggcctgtgg cgcggcccgg tgatggccgg tgcgccggtc ccggacgtgg tgcggccgga
     9421 cgtgaccgtg ctggacgagc agcggctgtg cgcgatcgag gacctggcgg aggtgcggct
     9481 ggcgctgggc tgcgcgttcg acctcgtgcc ggcgctggcc ggcctggtgg tggagcaccc
     9541 gctgcgggag cggttgtggc gcaacctggt cggcgcgctc gcggcggccg gccggcgcac
     9601 cgaggcgctg gccgtctacc accggctggt gcgggtgctg gactccgaac tcggcgtggc
     9661 cccgagcgcg gcgaccgccg agctgtacga ggccgttcgg cgcgaccggc gcgactgaac
     9721 gccggaaggc cacttcgccg tgtgcgctcc cgtgtgcaga gcatttctac actcgccgct
     9781 cctgctgagg aaggagtacg gatgactgcc gcactgctgc tcgacgccga ggagatggtg
     9841 gcccgctggc gggccggtct ggacgagtcg gacaacccgg ccggcccgct gttcgccaac
     9901 ggcgagttcg ccgagggcga catcgtggcg tgcaacccgc cgggcagccg ctgctcgtcg
     9961 tgcacggcgt cccgcccggt gtactgctgc tgaccccggt atgacccgcg acgaggtcgg
    10021 cgaactcgac cgaaccctgg aatggctgct cggcccggcg acggaccggt tgtcccgccg
    10081 gctggccgag gtcgccggcc tcggcgcgcc cgaggcgcgg gccctgctcg acgccgcccg
    10141 cgaggtcctg ctggacgtgg tgcggcgcaa ggtgatccgc gtgctcgtcc tggagctgaa
    10201 cgccgcccgc gtcaccggcg cgctgaccgc cgacgacccg gccggccggt gggcgcagtt
    10261 cctcgcgcac gccgccgagg agtcctactg gcacggtctg acccggcact acccgcacct
    10321 ggtcggccgg ctgcgggcga ccgtcgagaa ccgggtggcc gcgatcgcga ccctggccgg
    10381 gcgcttcgcc gaggaccggc cccggctggc cgcgctgctc ggcgcggacg cgggcgagct
    10441 gcgcaaggtc gagttcggcg cgggcgacag ccaccgcggc ggccactcgg tcaccctggt
    10501 gcactgcacc ggcggcacgg tggtctacaa gccacgcccg atggaggtcg accagcggct
    10561 ggccggcctg ctggcggtgc tgaccgccgg cgaccggtac ccgatccggg tgccggcggc
    10621 ggtcgtgcgg gacggctacg gctgggccgg gcacgtcgac caccggtact gcgcgaccga
    10681 ggacgagctg gccgcgttct acaccgccct gggccactgg ctggccgtga tgcgcctggt
    10741 gtccgggacc gacctgcacg ccgagaacat catcgcctgc ggcccggtgc cggtcgtggt
    10801 ggactgcgag agcgtcttca cgccccgccc gccgcacccg ccgaccggcg cgggcgaggc
    10861 caccgaccgg gtcgccgaac agctcaaccg gaccgtgctg cgcaccggcc tgctgcccgg
    10921 ccggggcgcg gggctggggt ggcgcggcgt ggacggctcg gcgatgggcg gcctgcccgg
    10981 cgagcagccc gacatcggcc tgccggacct ggtgggcgcg ggcaccgaca ccgcccgggt
    11041 ggcgatcgtg ccgcagcagc tcccgccgac ccgcaacctg cccagcccgc acccgaggct
    11101 ggcccaccac tggccgcggg tggtggccgg gttcgacgcg atggccgagc ggatcacccg
    11161 gctggaccgg gcgggcgcgc tggagccgct gctggcgggg ttcgccgact gcgtggtccg
    11221 ggtgatcgtc cgggacaccg agtcctacac cgagctggcc cggatgctgt ggcacccggc
    11281 cggcctgcac gaccaggccg ccgccgaggg cagggcccgc gcgctgctgg cccggcactc
    11341 gatgaacacc cggggacccg gcgacccgga cgtgcacgcc gccgaggtgg ccgaactgct
    11401 ggtcggcgac atcccggtgt tcaccaccac cccggccgag ggctggctgc acacccccgg
    11461 cgggctggtc tgcggtccgc gggtggacca ggtcgcgctc gcgctggaga actggcgcac
    11521 cgccgacctg gggctggagc gccgggtcac gcacgccgcc ctggtcagcg cctacctcaa
    11581 ccagggcgcg gaaccggagc tcggccggct gcccgcgccg ccgcccgacc ggaccggcct
    11641 ggaccggcgg cggcgggcgc tggccgccgg cctggtgcgc gaactggccg gcgaggcggt
    11701 ccgcggcgcg gacggcacgg ccacctggtt cgcgccgatc ctggaccgct ccggctggca
    11761 gaccacgccg ctgaccccgg acctgtacgg cgggacgctc ggcgtcgccg tgctgctggc
    11821 cggctaccgg cacgaggtcg cggcgggccg cgcggacgcc gtggacgggg tggcggagct
    11881 gctggccggg accgtgcgca cggcacggct gacccagcgg tggtgggccg agcaggccga
    11941 gcacacccgc cgccgacccg acccgaccgg cggctacatc ggcctgggct cgcagatctg
    12001 gtgctggctc gcgctggacc ggctcgggct cgccgccgac gacgagggcg accccgtgcc
    12061 ggacgcgctg ttcctggccc gccagctgcc cgccgcgatc gccgcgagcg aaggcccgga
    12121 cctggtcgtc ggcacggccg gcgcgatcgt gccgctgctc ctgctggccg agcggaccgg
    12181 tgacgaccag tgggtcgacc tggccgcgca cgccggccgc gcgctcgtcg cggacgcggt
    12241 ggtgaccggt gggcgggcgc actggcccgc cccgaactgg ccgggcggca tcggcggctt
    12301 cgcccacggc gcgaccggca tcgggtgggc gctgggccgg ctcgccgagg tgaccgggga
    12361 acgccggttc gccgacctcg cgcgcggagc cgccgcctac gaggagacct ggtacagcgc
    12421 ggagcgcggg gcgtggatgg acccgcgcga gcccgacacc gtcgccgccg cctggtgcca
    12481 cggcgcgatc ggcgtcggcc tggccaccga cgacccggag gtgctgcggc gggcggcgtc
    12541 ctccgcgctg cgcgacggca tcggctggac gcacaccctg tgccacggcg acctgggcac
    12601 ctgggagctg ctgaccgcgg cgctcgcggc cggcgtggca ccggacgggc tggaccgggc
    12661 cgggctggac gcgatggtgc tgggcagcct ggaggccaac ggccccacca cgggcctggc
    12721 gcgcgaggtg tactcgccga gcatcatgtc cgggtccggc ggcatcgcct accagttgct
    12781 gcggatgcac ccggacagcg acctgccgtc cgtgctgctg ttgggcgacg ggccggcgcg
    12841 gtgaccgggg aacccgaccc gcgcgagggc gcgctggtca ccccgcactg gcagttggac
    12901 gatgccgacc gcgcgccgcg ccgcaccctg cgcggcctgc cgtcggccac ctggccggtg
    12961 ctggcgatga tccggcgcgc cgcgcccggt cccgcgctcg ccgtcgtggt gatgcaggtg
    13021 gtgtccgggc tggcggcggc gttcggcctg ttcgccacga ccggcgtgct caccgagctg
    13081 ctggcgagcg gggcggccgg ggaccggatc gtcgccgccc tgccgcagct ggtgctggtg
    13141 ggcgcggcgt tcgggctgcg cggcgcgatg gacgtcggtg tcgcgctggc gcacgcccgg
    13201 atcacgcccg ccgtgcgccg gctggccgag gaacgcctgt actcggcgag cctgggcgcg
    13261 gacctcgcgt cgttcgacga ctcccggttc tacgaccgga tgcaccgcgc ccgcgaccgc
    13321 ggcctgttct tcctggaacg cgccgcggac aacctggtcg agctgatcgg gtcgctgctg
    13381 ggcatcgcgg cggcggccgg cagcctggtc gtgctgcacc ccgcgctgct cccggtgctg
    13441 ctgctggcgg tcattccgga cgggtgggcg gtgcagcgcg cggcgcggct ggcgtacgcg
    13501 agcgtcgggc gcaccgtggc gctggaccgg cgggtgcaga tggtgtcgga cctggccacc
    13561 gaacgcgaac cggccgccga gatccgggcc taccgggcgg agccgttcgt gctgcacgag
    13621 taccgcgtgg cggcggaccc gctgcgggac gaggaggtcc ggctggccac cgcgcaggcc
    13681 agggtgcgcg gcatcggccg cgcgctggcc ggtgtcggcc tcgcggtgac ctacgtggtg
    13741 ctgggcctgc tggtccgcta cggctgggtg ccgctcgccg tcgcgggtac cgcggtgatc
    13801 gcgatccggg tcgccaccac cgccctgaac cggttggtgc tggccgcgaa ccagttggtg
    13861 gagcagggca tgtacgtcgc cgactaccag gacttcctgg ccgctgttcc cgattcctca
    13921 gcacccgatt ccgctgctcc cgatccctca gcccccgact ctgccgcggg aaagccgccc
    13981 ggcgcgggtc cgccgccgtt ggaccccggc cgggtcgtgc tcgaccacgt cacgttcagc
    14041 tacccggaga gcgcccggac cgccgtccgc gacgtcaccc tgaccatcga gccgggcgag
    14101 accgtcgcgc tggtcggcga gaacggctcc ggcaagacca cgctggccaa gctgatcgcg
    14161 ggcctgtacc cgccgacgtc cggccgggtg cggtggggcg ggcgggacct ggccgacgtg
    14221 gaccgccggc aggccgccga ccgggtgatg atggtgctgc aggacccgat ccgctggccg
    14281 cacaccgcgc gggtcaacgt ccgcgtcggc cggcacgagc gccccgaccc ggccggcgcg
    14341 gcggtgcggt cggcggccgg gcagtccggt gccgacgagg tcgtggcggg cctgcccgac
    14401 gagtgggaga cgttgctgtc caagcagttc cggggcggcg tggagctgtc cggcgggcag
    14461 tggcagcggc tcgccgtggc gcgcgggctc taccgcgacg cgccgctgct gatctgggac
    14521 gagccgaccg cgccgctgga cgccaaggcc gagttcgcgg tgtacgagtc gttgcgcgcg
    14581 ctggccgccg accggaccgt cgtgctgatc acccaccggc tggccagcgt gcggcacgcc
    14641 gaccggatcc tcctgctgca cgagggggaa ctggtggagc agggcacgca cgcggcgttg
    14701 ctcgccgccg gcggccggta cgccgagctg tacgagctgc agagccggat gtacgccgat
    14761 gcttgacctg gtgacgccgc gggacgagcg ctacgccctg tcccgcaccc agttcatcgg
    14821 ccggccggtc gaggtgctgc cgcgcgcggt ggcccggtgc gggtcggccg gcgaggtggt
    14881 cgaggcgctg gctttcgcgc gctcgcgcgg gctgccgttc gcgatccggg gcggcgggca
    14941 cagcaacgcc tgccactcca gcacgtccgg gctgctggtc gacgtgacgc cggccgaccg
    15001 gatcaccgtg gccgacgggc tggtcacggt cggcggcggc gtccggatcg gccggctggc
    15061 gcgggcgctg gccccgctgg gacggctggt cccgaccggg tcgtgcccct cggtcggggt
    15121 ggtgggggcg gcgctgggcg gcgggttcgg cagccacggc cggctgcacg ggctgacctg
    15181 cgacgcgctg gtcggggccg aggtcgtgct ggccgacggc cgggtggtcg ggacggccgg
    15241 cgagccggac ctgctgtggg cgttgcgcgg ggccggcggc ggtctcggcg tggtgacctc
    15301 ggcgaccttc cgcacggtgg cggcgctgcc ccgcacgcac ttccgcctgg agtgggggtt
    15361 cgagcacgcc gccgccctgg tcgcgtggtg gcagcggtgg gcaccgggcg cgccggacgg
    15421 cgtctcggcc gaactcgtgc tgctgggccc gcagtacccc gaggagccgc cggtggcgct
    15481 gctgatcggc gcggcaccgg accgggcggc ggtgcaggcg ttcgccgacg acttcggccg
    15541 gcccgccgtc gccgagatcg ccgacctgtc ggcggccgac gcggcgctgc tgcacgcgac
    15601 cccgtactcc gccgtcgcgc acgacccgtc ggagatccca ctggtgcacg accgtcccgg
    15661 gctgtccacc gcgaccaccg ggttcttcgc ccggccgctg cccgatgacg cggtggcggc
    15721 gctgctggcg cacttcaccg ccgaccgggt gatgggggag ttgcgggagg tggcgttcac
    15781 gccgtggggc ggcgggtacg cccggacccc cggcgacgcc accgcgttcg gccaccgcga
    15841 cccggcgttc ctggtcaagc acacggtcct ggtcggtccg ggcggcgcgg cccgccgggg
    15901 cgaggtcgtg ctggcgcggg cgcgggcggg ccgagacctg ctgcgcccct gggggacggg
    15961 cggcgcgtac gtcaacttcc ccgagccggg cctgcccgac cacgcctacc acggggcgaa
    16021 cgccgcgcgc gtgcgcgcgg tgaaggcgca ctacgacccg ggcggcgcgt tccgacccgg
    16081 gtgaaccgac tggggtgaac cgactggggt gaccggggac gggccccggc caccccgggt
    16141 gactcagcgg cggcccggca cccggtccgc gacgatcatc aggtagtgga agctgccctc
    16201 gcggtacgcg gtcaggaacg acgactcgac gcccgtggcc accgacgacc tctcccgcag
    16261 ttcccagtac gggatggtgt gcggggtcag gtcgacgacc tcgatcggca ccaggttgtt
    16321 ggccgccatc gccttgaagt acgcgctgcg cgggtggacg ctgcacgtgt accgctcgtc
    16381 gatctggctg accgccttcg accggccgcc ggtcaggtcg ttgtagcagc cggtgatgca
    16441 gacgtaccgg ccaccgggcg cgaccagccg ggagaattca ccgaacaggt cgaacaggtc
    16501 gacgtacatg gtggtctcat tggtccacac cccgcggaat gcgccggtct cgaaaccggt
    16561 gtcgagcatg ttccggaagt ggaaccggac ctggtccgcg acaccccact tggcggcctg
    16621 gttgttggcg aattcgacct gcttctccga gatggacacg ccgtccaccc ggcagccgta
    16681 ccgccggttg gtcatgatgc tggtgccgcc gcgacccgaa ccgccgtcca gcagccggtc
    16741 ctgcgggccg gtccccgcga accggtcgat caggaagtcg gcctgggcgg tctccagccg
    16801 gtgcagctcg gcgatcaccc gtgcgtcacg ggtctcctcg ggtcctacca gcacggactc
    16861 gtcgtagggg ccgatgccgt agtggtggtg gtagatcccg tcgacctcgc cgagccggat
    16921 gttcaccggg tcccgttcgg cgttccagta cgccgcgacg gaccgctggt agtcggtgcg
    16981 caggacaccg ggagcgacag tggtcatggg cgggtgttct cctttttcgt tcgcgccgat
    17041 gcgcaacacg attgccggcg aatacaaatg cggtgaatcg atgtggagtg ctgtttattc
    17101 ctcggtcgcg accgtgctcg acgctagcat cggctatttg accgtgtaca gtcacccgaa
    17161 tgggtaaggc ggtgggccga accggcggcc tgctccggtc ggcgcgccgg caatacccga
    17221 ttcggtcaac aggccgcatt ccggggacgg accgtattcg tccggcccgg tcccggcggc
    17281 ccccgggacg ccgcggcggc ggcactgcgg gcgcggtgcc gcccggacgg ccgcgccggt
    17341 ggtgaccacg agtaccggcc gcggctcggg gtggccggtg ccggaagcac caccggccac
    17401 ccccgtctgc cgcaacggcc cggccccggc ggacgggtca ggccgagccg gtggcggtga
    17461 gcaggaacgc gggcgaggac cagtagtcga acagcggcgt gatctccacg tcggcgaacc
    17521 cggcgcgggt cacctgcgcg acccaggcgg cggccggctg ctcccaggtg gagcgcaccg
    17581 cgccgggcag cagctgcccg gtcagcaccg gcatcaggaa cccctgcgcg acgaggtcgc
    17641 ggtcgtcgtc gtacttggcc agcccgcgct cgtaggtctc ggcgaggaac tccagccgcc
    17701 gctggggcga caggtcgggc acgtcgaact cgaccacggc cagcgtcccg acgtgcgggg
    17761 cgagggcggc caggaccgcg tcgcggacgt cgtgcgggag cgcgtgcagc gcgaacgtcg
    17821 actgggccac gtcgtgccgc ccgggtccgg tcacgaactc ctcgaccccg gtgttgcgcg
    17881 cgtccacgac cagcccgtcg ggcagccgct cgacggcggt ccgcagcaac gccgtggacg
    17941 gctccaccac ggtgacccgg ggccggtggc cggccagtgc gggcaccaac gcccgcccgt
    18001 cgccgcaccc gacgtccagc agcgcgccgg gccgcacccg gtcgtagagc gcggtcaacg
    18061 ccccgctcac cgcttcgtac agcccgacgt tcccgccgcc gtcgatgaac gcctggaacg
    18121 cggccggccg gtcgtacacc gtcccgtccg cgtcactgcc caggtactcc gccaacgcgg
    18181 tgccgagcgg tgaaccgacc cgggccgcga actcgcgcgc ccggtcccgt tcaccggcgg
    18241 tcagcgcccc caacgcagaa atgatcgtca ccggcccagc ttcgcaaacc cgtcgacccg
    18301 tcgtggccgg cggttgctcc atcggtgcga cccggtggaa atcgggcggg agttggggga
    18361 acgtcgaagg gagtcggctc tcggtccgtg gaggtggcgg tcgtggcgcg tgtccgtttg
    18421 gttccgggag gccgtgaagt ggacctcgac tgcctttccg ccgccgaccg ttgcgcgata
    18481 gtggcgttgc gcggcgaagt gcggcgcggt gatcgggtgc tgctctgcct cgaacagccc
    18541 gaagacgacg agttgttcgt gcgggaggtc gacggccggt atttcgcgag ccacttcgcg
    18601 ggcgggcggc ccggttcgca cggcgcgcac gagatcgtgg cggagaccga cgagcaccag
    18661 cggcagcggg agtactggta ccgcgcgggg caggatgccg agttctccag cgagaggtcc
    18721 tttcgcacgt ccgccgggaa cgtgctcgac gtggcgatcc acggccggac gcgtaccggc
    18781 gtgcaactcg aacactcccg cctcaccgcg gcggtcgcgc accagcgcac cacgcgtgcg
    18841 ggtcgggccg gctggttgtc gttgtggttc accgccgccg accgtgtccc gaagtggttc
    18901 caccgggtgc cgtcggtggg ctgcaaccac atcgcgtggg acgccctgcc gcccaggggc
    18961 accgcgcagg cgacggggct gaagaaggtg caggccgtca agtgcaccgt ccacgacttc
    19021 ggcggcaagt gcccggccgg gaagcaccgt ccctgcggca ggttccaccc gcagttcgtc
    19081 gcgtggcacc aggtcacgtt ggacaaggtg gcctacttcg tcccgtccgg gcgcgcggtg
    19141 ccgctgctga ccccgcgccg cgaggtcgtc ctggtgccgc cggaagggct cgcgctctac
    19201 gagtcgctta ccggacgatc cgcccgctac gccgccgaaa agttctcgca ttccgcggtg
    19261 cggtgcgaac aatgcgacaa cgccctgttg tggatccgtc cgggccgggt ccgctgcgaa
    19321 cagtgcgatc cgatcatgaa tcttcctcgc tctccctacc cgctctgacc gcgcgcacgg
    19381 cgcaggccgc agttcggcgt tttccgcact gatgcgggag tctcgcctca cctgcggttc
    19441 ttcgcgcggg gatcacccgc gcggtgccgg cctgccgctg taggggctag cggccactgg
    19501 cgcaggtggc cccgggagcc accgggggaa tggcggaagt tgctgtgccg caagtgttct
    19561 cacccttgct gtcctttggt ccaatcggcc ttcccggtaa cggcccgcac tgcgccaccg
    19621 atgcccggcg tggaaccggg gccgcgtggc cttgggggag aggcaggaaa aagccatgtc
    19681 cttatccggt gccttccggc acagatccac cgcggcgtgg gcacggctgc tcgcagtcgt
    19741 cgtcttcgcc gctgtcctgg tcccggcggt ggccgtgccg cgggccgtgg cggaggcggt
    19801 ggcggcggct ccggcggtcg ggttcaccga ggttccgtcc ggcgcctcgg tcggcgagcc
    19861 ctacacgttc tccggcacgg tcggcgagcc cgcggcggtc gccgcggtgg aggtctccac
    19921 ggacggcggc gcgctgtggc ggccggccgg ctggtcggcc ggggcgacca cgtggacctc
    19981 ccgctacacg cccaccacct ccggccaggc gcaactgcgg gtccgggcgc tcgacgcagc
    20041 ccaggccacg gtgagcaccg cgtcggcgac gccctccgtc gcgccgcgca cctgcccgtg
    20101 cggcctgtgg ggtgacacgg acgcgccggg cgtccccgac ctcagcgacg gcgctgccgt
    20161 cgaactgggg ctgaagtggc ggtcctccac gtccgggttc gtgcgcggcg tccgcttcta
    20221 caaggggccc ggcaacaccg gcacgcacac cggcagcctg tggagcacca ccggggtccg
    20281 gttggccacc ggcaccttca ccaacgagac ggccggcggc tggcagacgc tgctgttccc
    20341 gtcgccggtc gaggtcgagg ccaaccggac ccacgtcgtg tcctacctgt cgcccaccgg
    20401 gcacttctcc gccgacaccg gctacttcgc ccagtccgcc cgctacctgg agccgttgac
    20461 cggcgagcgg tccacgcccg gcaacggcaa cggcgtgttc caccccggcg gcggtttccc
    20521 cgaccagacg gcgcaggacg ccaactactg ggtcgacgtg gtgtgggcga ccgagcccgg
    20581 cgtcgacacc cgcgcgccgg cgctgaccgg cacctcgccg gtcggcgggg cgggcagcgt
    20641 cgcgctgtcc acggcgttga ccgcctccta cgacgaggtg gtcgacccgg ccgccgtcga
    20701 gttctcgctg accggcccgg cgggcccggt caccggttcc acgacggtga tcggcggcgg
    20761 ctccaccgcg cggttcgcgc cctccgccgc gctcaccgcc agcaccacct acaccgccca
    20821 ggcgcgcgtc cgcgacgccg tcggcaaccc gaccgactcg cacagctggg tgttcaccac
    20881 cggcgcgacc cggccggcgg cctgcccgtg caccgtctgg gacgacttcg ccaccccgct
    20941 cgaaccggcc accggcgacc cggcggccgt cgagctcggg gtgaaggtcc agttcaacgg
    21001 ccggggcgag gtgttgggcg tccggttcta caagggcgcg ggcaacaccg gcacgcacac
    21061 cggctcgttc tggtcgtcga ccggcctgct gctggctacc ggcacgttcg ccgacgagac
    21121 cacgaccggc tggcagaccc tgacgttcct caacccggtg accgtgcagg ccaacacgac
    21181 ctacgtcgtg tcgtacttcg cgccccacgg ccgttacgcg gtcgacccgg acttcttccg
    21241 cgacccggcg ggctacggcg gcatccgcgc gttgcagacc ggcgtggacg gggccaacgg
    21301 cgtgttccgc tacggcggcg gcttcccgac cgcgagccac aaccagaaca actactgggt
    21361 cgacgtgatc taccgcaacg gcctcaacgg cgaccgcacc ccgccgaccc tggtcgccgg
    21421 cacgcccgcc acggacgcca cgggcgtgcc cgtcggccgg tcggtgtcgt tgacctacag
    21481 cgaaccgatc gacccggcgt cgccgcaggt gtggctgacc gacccgggcg gcgtgaagct
    21541 gctcggcacg tcacggctgt ccgaagacct gaagacggtc gtctggacgc ccaacggccg
    21601 gctggcaccc gggacgcgct acaccgtgaa cgcgctcgcg gccgacgtca acggcaactc
    21661 ctccgccacc acgtcgtggt cgttcaccac gcagacccgg gccgactgcc cgtgctcgct
    21721 gttcagcacc gcgaccgtgc cgaccacgca gtccgtggcc agcccggtct cctcggagtt
    21781 gggcgtgcgg ttccaggccg tctacaacgg caaggtgacc ggcgtccggt tctacaaggg
    21841 cgcggccaac accggtacgc acaccggcac gctgtgggcc gccaacggca cgcggctggc
    21901 caccggcacg ttcgtcgacg agaccaccgc cgggtggcag acgctggcgt tcgcgacgcc
    21961 ggtcgacatc cgcgcgggcc aggtctacgt ggcgtcctac accgccccca acggccagta
    22021 cgccctggag tcgagcttct tccagccgcg cggcgtcgac tcgccgccgt tgtcggccga
    22081 ccgcaacaac ggggacagcc ccaacggcgt ctacgcgacc ggcggagcgt tcccgaccac
    22141 cagctacaac ggcaaccagt actgggtgga cgtggtcttc acgttcagcg gcgacgtcgt
    22201 gcccccggtg cacagcagcc acacgccgtt gaccgacgcc accgaggtcg acctcaccgg
    22261 ccccgtcacc gcgtccttcg acgagccgat cgacctgacg aacaccacgg tcaccgtcac
    22321 cgacggcggt ggcgcgcgga tcgcgggcaa gctcacccgc acaccggacg gccacacggt
    22381 cgtctggacg cccgacgcgc gcctgtcggc caacacccgg cacacggtcg tggtccgcgc
    22441 cgccgacgag acggcgaact acgagccgca gcccacgacg tggcggttca ccaccacgtc
    22501 gacgcaggaa tgtccgtgct cgctgttcag cagcgcggcc gtgcccgatc tcgcgtggga
    22561 accgctcgtc cactacaaca acgtcgggat caggttcgcg ccgaccgtcg acggcacggt
    22621 gaccggcgtg aagttccaca agaccgggtg gaacccgggc ccgcacaccg gctcgctgtg
    22681 ggcggtggac ggcacccgcc tggccacggg caccttcacc gaggagaccg cgaccggctg
    22741 gcagaccctc acgttcgaga cgccggtgcc ggtgaccgcc ggaacggact acgtcgcgag
    22801 ctacacaccg ggcgcgcacc cgtcgcggag caggacctac ttcg
//
