LOCUS       NC_019673              25325 bp    DNA     circular CON 12-DEC-2024
DEFINITION  Saccharothrix espanaensis DSM 44229, complete sequence.
ACCESSION   NC_019673
VERSION     NC_019673.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Saccharothrix espanaensis DSM 44229
  ORGANISM  Saccharothrix espanaensis DSM 44229
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Pseudonocardiales; Pseudonocardiaceae; Saccharothrix.
REFERENCE   1
  AUTHORS   Strobel,T., Al-Dilaimi,A., Blom,J., Gessner,A., Kalinowski,J.,
            Luzhetska,M., Puhler,A., Szczepanowski,R., Bechthold,A. and
            Ruckert,C.
  TITLE     Complete genome sequence of Saccharothrix espanaensis DSM 44229(T)
            and comparison to the other completely sequenced Pseudonocardiaceae
  JOURNAL   BMC Genomics 13, 465 (2012)
   PUBMED   22958348
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9360653)
  AUTHORS   Rueckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2012) IGS, CeBiTec, Bielefeld University,
            Universitaetsstr. 27, D-33335, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000328705.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:06:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,451
            Genes (coding)                    :: 8,313
            CDSs (with protein)               :: 8,313
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 43 of 138
            Pseudo Genes (incomplete)         :: 116 of 138
            Pseudo Genes (internal stop)      :: 7 of 138
            Pseudo Genes (multiple problems)  :: 27 of 138
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:45:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1696766
            Orig. end                         :: 1722091
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE804045.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25325
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25325
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25325
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15325](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15325)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            366..704
                     /locus_tag="BN6_RS08060"
                     /old_locus_tag="BN6_16420"
     CDS             366..704
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099077.1"
                     /locus_tag="BN6_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16420"
                     /product="hypothetical protein"
                     /protein_id="WP_015099077.1"
                     /transl_table=11
                     /translation="MDAKLAEELRLLLDAAAERAQPWLNKLADGEHGEHGERTCGWCPL
                     CNAVALVRGDRSELATRAAEHVAGLIAVLRAALAEPAAAGPADPSDAEEEREPRVQHIP
                     VVRRRTQC"
     gene            698..1669
                     /locus_tag="BN6_RS08065"
                     /old_locus_tag="BN6_16430"
     CDS             698..1669
                     /codon_start=1
                     /function="Required for glucose repression of many
                     different genes"
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099078.1"
                     /locus_tag="BN6_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16430"
                     /product="ROK family protein"
                     /protein_id="WP_015099078.1"
                     /transl_table=11
                     /translation="MLTVGVDVGGTSVRVGVVDADGAVLDTARAATPSGEGALEEAIGA
                     AVAEVASRHRVAAVGLAVAGFVASDRRTVLFAPHLAWRQAPVADRIAERVGLPVVLEHD
                     ANAAALAEHRFGAARGAGIAVLVAIGTGIGGALLIDGKVFRGAHGVAPELGHLRLVPDG
                     RPCPCGKNGCWERYCSGTALTTTAVELLARHPGVSTSLAREALGDSRAVTGRRIAAAAR
                     DGDPLAKRAMIDLARWLGEGLALVADVYDPEVVVIGGGVSESAPLFLDEARERYAAVVT
                     GAGHRPLARIRTAQLGDDAGIVGVATLARDLTTTRPAHNGRR"
     gene            complement(1873..2376)
                     /locus_tag="BN6_RS08070"
                     /old_locus_tag="BN6_16440"
     CDS             complement(1873..2376)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099079.1"
                     /locus_tag="BN6_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16440"
                     /product="hypothetical protein"
                     /protein_id="WP_015099079.1"
                     /transl_table=11
                     /translation="MNSRRDSTDGPEDVDATFAEIVAGLEREGVGRTWPDADDAAADAA
                     ADAADDAADEEAEPAKPARSEGRPAVATADADPDDEPDDDPDDHFVPPDPPPLPALRAG
                     TVAALLLILLGVVLLLFPSLFGLTPTIGTPVALVVLCSGAGWLVLRIRNGPPPDSGWDD
                     GAVL"
     gene            2578..3351
                     /locus_tag="BN6_RS08075"
                     /old_locus_tag="BN6_16450"
     CDS             2578..3351
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020421003.1"
                     /locus_tag="BN6_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16450"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_041312262.1"
                     /transl_table=11
                     /translation="MLYWLMKHILLGPLLKLFFRPKIIEGAENIPKEGGAILASNHLAV
                     SDSFFLPLKLSRRVTFPAKIEYFTGKGLKGAFQRWFFSGVGQVPIDRSSASAAQGALDT
                     GVRIVREGKLLGIYPEGTRSPDGRLYKGKVGVAWIALESGAPVIPIAMFGTDKANPIGS
                     KMWRPHPIRIKIGKPLDFSRYEGLSGDRFVLRSITDEIMYALMELSGQEYVDVYAAKAK
                     EEPQKKPEKDSRKKPEGQGSGAPGDADRLPGTKAG"
     gene            3374..3886
                     /locus_tag="BN6_RS08080"
                     /old_locus_tag="BN6_16460"
     CDS             3374..3886
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800235.1"
                     /locus_tag="BN6_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16460"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_041316321.1"
                     /transl_table=11
                     /translation="MRFFYDCEFIEDGLTIDLVSIGVVDEEGREFYAVSTEFDPEKAGP
                     WVRANVLNQLPSPADQAWRGRERIRRDLLEFLGGAKTNRDDIELWAWFAAYDHVALAQL
                     WGPMPALPRCLPRFTRDLRQRWEDVGKPKLPAPPADAHDALADARHNLARWQVIEAERR
                     RRGFAVR"
     misc_feature    complement(3390..3408)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.92"
                     /tool="antismash"
     gene            3966..4991
                     /locus_tag="BN6_RS08085"
                     /old_locus_tag="BN6_16470"
     CDS             3966..4991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004558616.1"
                     /locus_tag="BN6_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16470"
                     /product="6-phosphofructokinase"
                     /protein_id="WP_041312264.1"
                     /transl_table=11
                     /translation="MRIGVLTGGGDCPGLNAVIRAVVRKGVEGHGWEIVGFRNGWQGPV
                     EGLTKPIGLGDVEDILTRGGTILGSSRTNPYKIEGGVDRIREVLAAEGVDALIAIGGED
                     TLGVAKRLTDDGIGVVGVPKTIDNDLGATDYTFGFDTAVHIATESIDRLRTTAESHHRA
                     LVVEVMGRHAGWIALHSGLAGGANVILVPERPFSVEKVVEWVERRFERQYAPIIVVAEG
                     AVPEGGAEVLHSGEKDAFGHVRLGGVGTWLAEEIAERTGQESRAVVLGHTQRGGIPTAY
                     DRVLATRFGLHAVDAVAEGDFGVMVALRGTDIVRVKLSEATAELKTVPLERYAEAEVFF
                     G"
     gene            5443..6831
                     /locus_tag="BN6_RS08090"
                     /old_locus_tag="BN6_16480"
     CDS             5443..6831
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015800237.1"
                     /locus_tag="BN6_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16480"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_015099083.1"
                     /transl_table=11
                     /translation="MNWTVDVPVDTLPELPPLPPELRNRLDEALSRPAAQQPEWPDAEQ
                     VRRVRAVLESVPPITVPAEIDRLRGNLAEVARGEAFLLQGGDCAETFADNTEPHIRANV
                     RTLLQMAVVLTYGASLPVVKIGRIAGQYAKPRSSNIDALGLPSYRGDIVNSLITTPEAR
                     VPDPSRMIRAYANAGAAMNLLRAMTTAGMADLHRLHEWNKDFVRTSPAGERYEALAAEI
                     DRGLRFMSACGVQDSSLHTTEIFASHEALLLDYERALLRLDSNSDQPKLYNLSSHFLWI
                     GERTRQLDGAHIAFAELLANPIGLKIGPSTTPEMAVEYVERLDPRNEAGRLTLISRMGN
                     GKVRDVLPAIVEKVTASGHQVIWQCDPMHGNTHESSTGYKTRHFDRIVDEVQGFFEVHR
                     RLGTHPGGIHIELTGEDVTECLGGAQEISDTDLAGRYETACDPRLNTQQSLELAFLVAE
                     MLRS"
     gene            complement(<7120..7287)
                     /locus_tag="BN6_RS48430"
                     /pseudo=""
     CDS             complement(<7120..7287)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016840.5"
                     /locus_tag="BN6_RS48430"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="type I restriction endonuclease subunit M"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRWDDETARGTDLWATEHETRAGIVERYRRVWAHSAATVDAFDA
                     PGHVPWWPRPD"
     gene            complement(7384..9429)
                     /locus_tag="BN6_RS08095"
                     /old_locus_tag="BN6_16490"
     CDS             complement(7384..9429)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671593.1"
                     /locus_tag="BN6_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16490"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_041312267.1"
                     /sec_met_domain="Pkinase (E-value: 3.6e-47, bitscore:
                     159.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERSATNVIGGLLEQRYRVGTLVARGGMSTVYRGVDTRLERPVAI
                     KVMDPRFSSDPQFVARFEREARAAAGLHHPGVVAVHDQGVDEDRVYLVMELVEGGTLRD
                     LITARGKLDVPLALTVLERVLSPLAAAHRAGLVHRDVKPENVLIGRAGVVKVADFGLAR
                     AVSTPAITSDTTILGTVAYLSPEQVTNGNADARSDVYSAGVLLYEMLTGAPPYVGDTAI
                     SVAYRHVNEEVPPVTGVPAEVAELVRRSTRKEPFLRPADAEAFLSEVETARATLGLAAV
                     DVPTVTAATADTPASAEPKTERVQPVGVGAVAFAEATVPVRRFPPPGPQGTQALPRGLD
                     PTPSPAMGVPAPLGGQQTAVVPRTRPVRPKRPPKKKTPEQLYEEMRAKSKKQFITWISV
                     VAVAAVVVGLVSWWLSIGRVESVPDVVGKEQDAAVAILESANLKSAVSTENSNTVPSGQ
                     VLSTDPAPGAEATRGDLVRVVVSRGKPVVPQVAAGSDPAAAEREIAAVGLKSKLDPNDD
                     AFSDRVPKGKVVTTKPAPGTAVEIGSVVTVVLSKGVQPKPVPNVKGKTKDEAFAELAAA
                     GFDPVEGPEEPSGEVDGGRVVRTNPVAGTTLGADKRVTVIVAADRGVTVPNVEGKKLRE
                     AKETLEKAGFQVEVQFNNRERATVINQSIRPGERVPKGTKITIIAV"
     gene            9615..9980
                     /locus_tag="BN6_RS08100"
                     /old_locus_tag="BN6_16500"
     CDS             9615..9980
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="BN6_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16500"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_197540245.1"
                     /transl_table=11
                     /translation="MSAIPAAADVLAPDLEVLDLPEVGERLGLPVTRVHQLLRDGQLLA
                     ERRNGVLVVPSQFLAAGGVVKGLPGTITVLRDSGYSTDEILRWLFTEDDTLPGTPIEAL
                     RGDRGREVKRRAQSMGF"
     gene            complement(10001..10933)
                     /locus_tag="BN6_RS08105"
                     /old_locus_tag="BN6_16510"
     CDS             complement(10001..10933)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /function="Phytoene/squalene synthetase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099086.1"
                     /locus_tag="BN6_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16510"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_015099086.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.8e-109,
                     bitscore: 361.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.8e-62,
                     bitscore: 208.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPALADAYARCRELNARHGRTFFLATRLLPPVRRPAVHALYGF
                     ARWADEIVDSGTSADPAGELDVLERQLADELAGRPTGHPVLAALADTVRRYRIDPALFA
                     DFLASMRMDLHTTEYATLAELDRYMRGSAEVIGLQLLPVFGTIAPLSHAEPGAAALGRA
                     FQLTNFLRDVGEDLDRGRVYLPQDVLRVYDVNRELLAWSRRTGKPDERIRRAVRHLTAV
                     AYAAYREAETAVPLLHPVARPCVRTALVLYREILDGIAVADHHVLDKRVVVSNARRLSV
                     ALPGLSRSVAARATSGRLRWNRPDAPGRS"
     gene            complement(10930..12348)
                     /gene="mptB"
                     /locus_tag="BN6_RS08110"
                     /old_locus_tag="BN6_16520"
     CDS             complement(10930..12348)
                     /codon_start=1
                     /gene="mptB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099087.1"
                     /locus_tag="BN6_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16520"
                     /product="polyprenol phosphomannose-dependent alpha 1,6
                     mannosyltransferase MptB"
                     /protein_id="WP_231905134.1"
                     /transl_table=11
                     /translation="MRTILLGVAGVMLVALGGTGAGATLKRDPLLADTTLSWIRYGHGQ
                     DLATAVLYLGLGLVIWSWIRLGRMVRNGHVGSSAVLTAIVVWTLPLLFAPPLFSKDIYS
                     YLAQGQIALNGLDPYKVGPAVLQSPLSDNVSWVWQNTPAPYGPVFLVLAMSVVWATHAS
                     VIGGVVLMRFVLAIGLALLCWALPGLARHLGGRPAVALWLAAANPLMLVHLIGGAHNDL
                     LMVGLMAAGCLFVLDGRHVLGIAVVTLAFAVKATAVVALPFLVLVWARRLAGSRTVQLV
                     KAIAGGLATFLVVFTATTLLSGLDLGWIPALSSSSTIVNWLSLPSAVGDFAHTVVNLVV
                     RVEPGVFLTVARGLGSLLLLFIAWRQWRAAADGGPEAIRRAAITSLAVALLSPATLPWY
                     FSWALVLAAGLAWSTKGLQAAAFFSTFLLLVTFPDGDTALYSWGYLALIAAVSALACVS
                     LVKPDPLKLSSRYP"
     misc_feature    12584..12597
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.86"
                     /tool="antismash"
     misc_feature    complement(12664..12677)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            complement(12762..14255)
                     /gene="crtI"
                     /locus_tag="BN6_RS08115"
                     /old_locus_tag="BN6_16530"
     CDS             complement(12762..14255)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Phytoene dehydrogenase and related proteins"
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099088.1"
                     /locus_tag="BN6_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16530"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_015099088.1"
                     /sec_met_domain="DAO (E-value: 1.1e-16, bitscore: 60.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVTGRTDHVVVVGAGLAGLSAALHLLGAGRRVTVVERDDLPGG
                     RAGRLDLGDYRFDTGPTVLTMPELVDEALDAVGESLADRLDLAPVEPAYRARFADGDVL
                     DVHADGDAMEAEVRRFAGPAEAAGYRALRSWLTELYRVEKDAFIGANFDSPIGLLTPRL
                     ARLAALRGFARLGPSVARFLKDERLQRVFSFQSLYAGVPPRKALAAYAVIAYMDTIAGV
                     YYPRGGMRALPDALAGAARDAGADLRYRTKVAWLERIGGRVTAVRTTQGERIPCDAVVL
                     TPDLPMSYRLLGHRPRRPVPITWSPSAVVLHAGVDRTWPELAHHTLFFGRAWDRTFDEL
                     TRRGSLMSDPSLLVTSPPGRGMFVLAPVPNLRVGPVDWERVGPAYRDEVVQTLQARGLT
                     GFGDSIEVERLVTPKDWAGMGLAAGTPFSAAHTFAQTGPFRPRNLVLDNAVLAGCGTTP
                     GVGVPPVLISGRLAAQRITGATGAAWRRPAARTRAHSPR"
     gene            complement(14258..15325)
                     /locus_tag="BN6_RS08120"
                     /old_locus_tag="BN6_16540"
     CDS             complement(14258..15325)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Geranylgeranyl pyrophosphate synthase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332689.1"
                     /locus_tag="BN6_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16540"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_015099089.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-43, bitscore:
                     147.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPHPLDLELPKHVDAALAGYLADRRALGGRMEENFTGAVDALAD
                     FVLGGGKRIRPTFAWWGWRAAGGDPDGELAAPVLTAVSSLELIQACALIHDDLMDASET
                     RRGMPTVHVRFARRHLAEGWLGEPERFGLAASVLIGDVALAWADDMLFAAGLPNDALQR
                     LSLPWRDMRTEMLAGQYLDVLTQARGDASPDAALRIDRLKTAAYTVERPLHMGAAIGDA
                     SPELVAGLRAFGTDIGVAFQLRDDLLGVFGDPAVTGKPAGDDLREGKRTLLVALGMEFG
                     ADVLHDALGRPDLDVAEVDEVRARLVEVGAVAAVEDRIARLTESALAALADAPVADPAG
                     DRLAELAISATKRTY"
     gene            15431..16315
                     /locus_tag="BN6_RS08125"
                     /old_locus_tag="BN6_16550"
     CDS             15431..16315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099090.1"
                     /locus_tag="BN6_RS08125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16550"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_015099090.1"
                     /transl_table=11
                     /translation="MTSVVERLSGGTPVFSVEFFPPRDDADEQVLWRAIRELEGLDPAF
                     VSITYGAGGSSRDRTIRTTGRVVQETTLVAMAHLTAVSHSVAELRNVIGWYAAVGVRNI
                     LAVRGDPPGDPHGEWVPHPDGLTYAEELVRLCRELGDFCVGVSAFPYGHPRSGDLDTDL
                     KHLINKLRAGADFAIAQLFLEPEHFLRLRDRIAALGHETHLLPGLMPLTTPRTLAKCVE
                     LSGAPLPVSVARRLEPLADDPKAFRSAGVDLVTEMGERLLAEGVPALHFYTFNRSKATR
                     EVVGRLGLVPART"
     gene            complement(16374..16808)
                     /locus_tag="BN6_RS08130"
                     /old_locus_tag="BN6_16560"
     CDS             complement(16374..16808)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298: putative carboxymuconolactone decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099091.1"
                     /locus_tag="BN6_RS08130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16560"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_015099091.1"
                     /transl_table=11
                     /translation="MNLAEVAPEVYQALLQIDGYAHQHLDHGLIELVKLRASMLNNCAY
                     CVDMHSTDAIKAGENPQRLFAVSVWHESRFFTETERVALEFTDAVTRLGEHGVPDELWA
                     KVTATFDQAQVAGLLAQLIAINGFNRVAVPLDSATERRLH"
     misc_feature    complement(16800..16815)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(16887..17537)
                     /locus_tag="BN6_RS08135"
                     /old_locus_tag="BN6_16570"
     CDS             complement(16887..17537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099092.1"
                     /locus_tag="BN6_RS08135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16570"
                     /product="LppM family (lipo)protein"
                     /protein_id="WP_015099092.1"
                     /transl_table=11
                     /translation="MPRASALLLPVILLAMFALTGCIRLHAAMAVSPDDRVSGEIVAAT
                     PPTQDNDPGPQLRVPEELAGRVTTKPYKVDNYTGTQLFFSALTFEEVRTLSMATSASSS
                     RYQLGFRRSGDLVTLSGSVDLTQVPTDRADIQIKISFPGEVVDTNGREEESTTIAWSPK
                     PGQASMLTATLRYAGENSPSYFGWTMLVAGLTGAAALIVVVLAIVAHRRSLVA"
     gene            17643..19322
                     /locus_tag="BN6_RS08140"
                     /old_locus_tag="BN6_16580"
     CDS             17643..19322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099093.1"
                     /locus_tag="BN6_RS08140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16580"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_015099093.1"
                     /transl_table=11
                     /translation="MSPSPAGVHGISNQFVADYAAADPLTATFIGTPGHDDRLTDYSPE
                     GHAAREELATRALADITAAEPADAGEAAAKSVFLERVGLDVEIHRAGLWEGELNVLAGP
                     VQSLREVFDLMPTSTAEDWATIAKRLTAMPEAVANLRAGLAHSADKGKVAALRQVAKVA
                     EQCDTWSGRSGGKSYFATLIEQADVDTSLRTDLEAGAKAAAEAYADLAAFLRGDLAPKA
                     PKKDAVGEDVYRLWSRYFTGARLDLAEAYEWGWAEFTRIETEMKQVANRIKPGATLAEA
                     AAALDANPRYLVSGQAGLQSWMQDLSDKALLDVRDVHFELPDELMKLECRIAPPGGGVG
                     AYYTGPTPDFARPGRMWWSVPADKTEFSTWREVTTVYHEGVPGHHLQVATAVYQAEKLN
                     NFQRMMCWVSGHGEGWALYAERLMRELGYLEDDGDLLGMLDAHLFRAARVIIDIGMHLE
                     LEIPKGAGFHDGERWTPELGLEFMLTRTITDPAHVHDEIDRYLGWPGQAPSYKLGERLW
                     LAARDDARARHGAAFDLKTFHKDALEMGAMGLDTLRERLAEL"
     gene            19422..20051
                     /locus_tag="BN6_RS08145"
                     /old_locus_tag="BN6_16590"
     CDS             19422..20051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099094.1"
                     /locus_tag="BN6_RS08145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16590"
                     /product="CHAP domain-containing protein"
                     /protein_id="WP_015099094.1"
                     /transl_table=11
                     /translation="MARRLRRSATALAAAGALVLGAVLGAVPAQAQEHAPDEWRIRLEI
                     VDYAFSQIGAKENGPNGYPQRYQDVDQDVRRPVEWCGVFVNWAWTKAGVPQRPSMRPAE
                     GAPGVDQGHWATYWQKWGQQNSRWKPLADRDVEMGDAVVYGNYPSMVAHVGIVVEVSYD
                     ATGQKATHVRTVEGNVSDKVVYSKWRRLSDLNAGPGLKASGFVSPF"
     gene            complement(20395..20955)
                     /locus_tag="BN6_RS08150"
                     /old_locus_tag="BN6_16600"
     CDS             complement(20395..20955)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099095.1"
                     /locus_tag="BN6_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16600"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_015099095.1"
                     /transl_table=11
                     /translation="MTAAPSQRLVELSARELNSRLGEALALYVNAMNYPPGTAEQRAPM
                     WLAHMLRDGWRCVVALGEDDELIGIGYGYRGSVGQWWHEQVRHGLTLVSGPNSVEEWMR
                     DYFELTELHVLPTEQGRGIGEGLLRNLLAGVPTSRVLLSTPEGPSKAWRLYRRLGFADV
                     LRHYQFTGDPRPFAVLGRTLPLD"
     gene            complement(20952..21452)
                     /locus_tag="BN6_RS08155"
                     /old_locus_tag="BN6_16610"
     CDS             complement(20952..21452)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020419640.1"
                     /locus_tag="BN6_RS08155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16610"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_041312273.1"
                     /transl_table=11
                     /translation="MSALDHPGIRKVAAALAEAGHPEAADGIRVLADAVRTAAEAAQAV
                     DVPVGAIANSLLFAAVRGDEVAPLLVLTSGAHRADTDLLAGLAGADRIDRAKPDFVREH
                     TSQVIGGVSPLGHPAPIQTFVDVDLEQYAVVWAAAGHPHAVFPTTCAGLVDLTGGTPAK
                     VAR"
     misc_feature    21518..21533
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.27"
                     /tool="antismash"
     misc_feature    complement(21519..21532)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            21634..22059
                     /locus_tag="BN6_RS08160"
                     /old_locus_tag="BN6_16620"
     CDS             21634..22059
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099097.1"
                     /locus_tag="BN6_RS08160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16620"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_015099097.1"
                     /transl_table=11
                     /translation="MSTSTDFPSTHRVPLPLPPASAVSLLAQARDCAREAERATEPADR
                     FATAYLGAMRAAAAVLALRGRPHRGRARPTSVWVLLPALAPELREWAAYFASCSATRAA
                     VQAGITRQVDRRGADDLVRQAAQFTELVDEIMYEGRL"
     gene            22056..22817
                     /locus_tag="BN6_RS08165"
                     /old_locus_tag="BN6_16630"
     CDS             22056..22817
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099098.1"
                     /locus_tag="BN6_RS08165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16630"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_015099098.1"
                     /transl_table=11
                     /translation="MSRGLVGYGRLIDVVAAEAELLAASAQGQRPERQVAACPGLNLGE
                     TTRHVGSMFRMVAAWVREGRQPVAWQQDPAPGQTLSDYLRDGVGPLVDALSERAADDPC
                     ETWWPAERTCGFWARRLAHEATVHRLDVQSAAGLPLDPVPDDVAEDGADEVLSLWLGHR
                     LDVLGVRGTRESTVAIRTGRRVWIARTGPEPATAWQASPEEAESADADVTGPPALVYRW
                     LWGRIPDRDVETTGDHDAIAQLWALLRLATK"
     gene            complement(22818..24395)
                     /locus_tag="BN6_RS08170"
                     /old_locus_tag="BN6_16640"
     CDS             complement(22818..24395)
                     /EC_number="3.1.3.1"
                     /GO_function="GO:0004035 - alkaline phosphatase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015099099.1"
                     /locus_tag="BN6_RS08170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16640"
                     /product="alkaline phosphatase D family protein"
                     /protein_id="WP_015099099.1"
                     /transl_table=11
                     /translation="MAQLVLGPVLRHVDETSATIWVETDAACEVTVAGHRAATFRVAEQ
                     HFALVVVEGLTPGTSTPYDVRLDDRVVWPEPDYAFPAPRIRTGGVRRIVFGSCRAAKGG
                     AETDRLGPDALDAFATRMKDWPEDRWPGALLLLGDQVYADEPTPQVREWLARRRPEPEG
                     EVVSFREYAELYHESWADPEIRWLMSVLPTSMIFDDHDIRDDWNTSGTWRAEMADKPWW
                     RERIRAGLASYWVYQHIGNLGPAELADSELFTAVREAGGEDVRQLLEDFAEQADREAEG
                     RKSTRWSYRRDFGRVRLLVIDTRSGRILDGPERLMVGDEEFDWIERNAEGDVDHLLIGS
                     SLPWLMPHALSHFQSLNERQAARPGWRGRLGEKIRQVGDLEHWPAFRASFERLARLLHR
                     LGGAADAPGTICVLSGDVHHSYAARAEFAEPTKSQVLQLVCSPVHNDPPKIFRVVFRLS
                     WSKPLARVLRFWADRAGVSPDPVSWQRVSGPHFGNSVAVLEIIGRNARYRLETATDDGL
                     VETANLTL"
     gene            24420..25130
                     /locus_tag="BN6_RS08175"
                     /old_locus_tag="BN6_16650"
     CDS             24420..25130
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017983963.1"
                     /locus_tag="BN6_RS08175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BN6_16650"
                     /product="VOC family protein"
                     /protein_id="WP_015099100.1"
                     /transl_table=11
                     /translation="MTTRLTDVVVDSADPAESAEFWSGLLERPVVDRTADAVVVALDGS
                     ANLVFVPVAEPKVVPNRLHLDLVTTSPQHRERLPARARERGAVPVDIGQGAVPWEVLAD
                     PAGNEFCVLEPRDEYLGIGPVAAVVVNAADPVALAGFWSHATGLPVTRQGPGFASLRRE
                     DGFWLEFVQVTEPKVVKNRLHLDVAPPPDGDLVLEVARLEACGAVRADVGQSVVPWVVL
                     ADPEGNEFCVLTPR"
     misc_feature    complement(24421..24435)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
ORIGIN
        1 ggcccggtgc gcaccgtcga gcaccacgcc cgcgaaccag tcggcctggc cgcgctgctg
       61 gaggtcgccg aggccctcta cgcgggagcg gacccgctgg ccgggtccgg tgcggccggg
      121 ccgctggtcg acgtggtgcg ggtggacgac gagtacgagc tgcggctggc gctgcgggtc
      181 ggcgactcgg agctggagct ggcccgcgtg ggcgacgacc tggcggtgac cgtggacggc
      241 cggcgcaggc tgatcgccct gccgtcgctg ctgcggcggt gcgtggtggt cggcgcggaa
      301 ctggacgacg acggggtggc cgtgcgcttc cgccccgacc ccgacctctg gatgcggtga
      361 ggcacgtgga cgcgaaactc gccgaggaac tccggctgct gctcgacgcc gccgccgagc
      421 gcgcgcagcc gtggctgaac aagctcgccg acggcgagca cggcgagcac ggcgagcgca
      481 cctgtggctg gtgcccgctg tgcaacgcgg tggcgctggt ccgcggcgac cgctcggaac
      541 tggccacccg ggccgccgag cacgtcgccg ggctcatcgc ggtgctgcgc gcggcgctcg
      601 ccgagcccgc tgccgccggg cccgccgacc cttccgacgc cgaggaggag cgcgaacccc
      661 gcgtgcagca catccccgtg gtgcggcggc ggacgcagtg ctgaccgtcg gcgtcgacgt
      721 cggcggcacc agcgtgcgcg tcggcgtggt ggacgccgac ggggccgtcc tggacaccgc
      781 ccgcgccgcc accccgtccg gggagggggc gctggaggag gcgatcggcg cggccgtggc
      841 cgaggtcgcc tcccggcacc gggtggccgc ggtcggcctg gccgtggccg ggttcgtcgc
      901 gtcggaccgg cggaccgtcc tgttcgcgcc gcacctggcg tggcggcagg ccccggtcgc
      961 cgaccggatc gccgagcgcg tcgggctgcc cgtggtgctg gagcacgacg ccaacgcggc
     1021 ggcgctggcc gagcaccggt tcggcgcggc ccgtggtgcc gggatcgcgg tcctggtggc
     1081 gatcggcacc gggataggag gcgcgctgct gatcgacggc aaggtgttcc gcggggcgca
     1141 cggcgtcgcg ccggaactcg gccacctgcg gctggtgccg gacgggcggc cgtgcccgtg
     1201 cggcaagaac ggctgctggg agcggtactg cagcgggacc gcgttgacga ccaccgcggt
     1261 ggaactgctg gcccgccacc ccggcgtgtc gacgtcactg gcgcgcgagg cgctgggcga
     1321 ctcgcgggcg gtgaccggcc gccggatcgc cgccgcggcc cgcgacggcg acccgctggc
     1381 caagcgcgcg atgatcgacc tggcccggtg gctgggggag ggcctggcgc tggtggccga
     1441 cgtgtacgac ccggaggtcg tggtgatcgg cggcggcgtg tcggagtccg cgccgctgtt
     1501 cctggacgag gcccgcgagc gctacgcggc cgtcgtcacc ggcgcgggcc accgcccact
     1561 ggcccgcatc cgcaccgcgc aactgggcga cgacgcgggc atcgtcggcg tggccaccct
     1621 ggcccgcgac ctgaccacca cccgcccagc ccacaacggt cgccgctagc cgcagtgact
     1681 ggtcgggttg ttggcggcgt gtcgggttga agacgggtgg acctccggcc cggaccgggc
     1741 aacgaccacc gcctggcacc ctgcccggct cgatccacga tcacaaccac taccgagctc
     1801 acagcgccgt cgacggccga ccaaccaccc gaccgaccgc ctggacctca acgacaccac
     1861 gagtcagtac aactagagga ccgcgccgtc gtcccagccg gagtccggcg gtgggccgtt
     1921 gcggatgcgc aggaccagcc agcccgcgcc cgagcacagc acgaccagcg ccaccggggt
     1981 gccgatcgtc ggggtcagcc cgaacaggct cgggaacagc agcaggacca cgccgagcag
     2041 gatcagcagc agggccgcga cggtgcccgc gcgcagggcg ggcagcgggg gcgggtccgg
     2101 cgggacgaag tggtcgtccg ggtcgtcgtc cggctcgtcg tccgggtcgg cgtcggcggt
     2161 ggccacggcg ggccggccct ccgagcgggc gggcttcgcg ggctcggctt cctcgtccgc
     2221 ggcgtcgtcc gctgcgtcgg cggcggcgtc ggcggcggcg tcgtccgcat cgggccaggt
     2281 cctgccgacg ccttcgcgtt ccaggccggc cacgatctcg gcgaaggtcg cgtccacgtc
     2341 ctccgggccg tccgtcgagt cgcgtcggga gttcatcggc gtgccccaac cctccggtcg
     2401 tgaaggcgaa tcctctgcca gacttcatcg tcccacgagg ccgttgtgtt gcggattacg
     2461 gcggtcggtg ggacttgcga ccgtaccggc cgcaccgggc cgttcgttgt gcctggtgcg
     2521 gttggctccg taggctggcc cgcggggacc aagcacgtcg aggaggcgct gccggcagtg
     2581 ctctactggc tgatgaaaca catcctgctc gggccgctcc tgaagctgtt cttccgcccc
     2641 aagatcatcg agggcgcgga gaacatcccg aaggagggcg gcgcgatcct ggcgtccaac
     2701 cacctcgcgg tctccgactc gttcttcctg ccgctgaagc tgtcccggcg ggtcaccttc
     2761 ccggcgaaga tcgagtactt caccggcaag ggcctcaagg gcgcgttcca gcgctggttc
     2821 ttctccggcg tcggccaggt gccgatcgac cggtcctcgg cgtcggcggc gcagggcgcg
     2881 ctggacaccg gcgtgcgcat cgtccgcgag ggcaagctgc tcggcatcta cccggagggc
     2941 acccgctcgc ccgacgggcg gctctacaag ggcaaggtcg gcgtcgcgtg gatcgccctg
     3001 gagtccggcg cgccggtcat cccgatcgcc atgttcggca ccgacaaggc gaaccccatc
     3061 ggctcgaaga tgtggcggcc gcacccgatc cggatcaaga tcggcaagcc gctggacttc
     3121 tcccgctacg agggcctgtc cggcgaccgg ttcgtgctgc ggtcgatcac cgacgagatc
     3181 atgtacgccc tgatggagct ctccggccag gagtacgtcg acgtctacgc ggccaaggcc
     3241 aaggaagagc cccagaagaa gcctgagaag gactcccgga agaagcccga gggacagggc
     3301 tccggtgctc ctggggacgc cgaccggctg cccggcacca aggccgggtg aaccgcacct
     3361 taaggtgggc gcggtgcggt tcttctacga ctgtgagttc atcgaggacg ggctgacgat
     3421 cgacctcgtc tccatcgggg tggtcgacga ggaaggccgc gagttctacg ccgtgtcgac
     3481 cgagttcgac ccggagaagg ccggtccgtg ggtgcgggcg aacgtgctca accagctccc
     3541 gtcccccgcc gaccaggcct ggcgcggtcg cgagcggatc cgccgcgacc tgctggagtt
     3601 cctcggcggg gccaagacca accgggacga catcgagctg tgggcgtggt tcgccgccta
     3661 cgaccacgtg gcgctggcgc agctgtgggg cccgatgccc gcgctgccgc gctgcctgcc
     3721 ccggttcacc cgcgacctgc ggcagcgctg ggaggacgtc ggcaagccca agctgcccgc
     3781 gccgcccgcc gacgcgcacg acgcgctcgc cgacgcccgc cacaacctgg cccgctggca
     3841 ggtgatcgag gccgagcgcc gccgccgcgg gttcgccgtc cgctaggtgg gacccggcct
     3901 tgctgcaccg atccagctcg tgacagtctt gggtgaccca cgccacgaag agattggcta
     3961 agcagatgcg tattggtgtg ctcaccggcg gtggtgactg ccccggcctc aacgcggtca
     4021 tccgcgccgt ggtccgcaag ggcgtcgagg gccacggctg ggagatcgtg ggcttccgca
     4081 acggctggca gggcccggtc gaagggctca ccaagccgat cgggctcggc gacgtcgagg
     4141 acatcctcac ccggggcggc acgatcctgg gctcgtcgcg caccaacccg tacaagatcg
     4201 agggcggtgt cgaccggatc cgcgaggtgc tcgccgccga gggcgtcgac gcgctgatcg
     4261 cgatcggcgg cgaggacacc ctgggtgtcg cgaagcggct gaccgacgac ggcatcggcg
     4321 tggtcggcgt gccgaagacc atcgacaacg acctgggcgc gacggactac acgttcggct
     4381 tcgacaccgc cgtgcacatc gccaccgagt ccatcgaccg gctgcgcacc accgccgagt
     4441 cccaccaccg ggcgctcgtg gtcgaggtca tgggccggca cgcgggctgg atcgcgctgc
     4501 actccggcct cgcgggcggc gcgaacgtga tcctggtgcc ggagcggccg ttcagcgtgg
     4561 agaaggtcgt cgagtgggtg gagcggcggt tcgagcggca gtacgcgccg atcatcgtcg
     4621 tcgccgaggg cgcggtgccc gagggcggcg ccgaggtgct gcactccggt gagaaggacg
     4681 cgttcggcca cgtccggctg ggcggggtcg gcacctggct ggccgaggag atcgccgagc
     4741 gcaccggcca ggagtcccgc gcggtcgtgc tcgggcacac ccagcgcggc ggcatcccga
     4801 ccgcgtacga ccgggtgctg gcgaccaggt tcggcctgca cgcggtggac gcggtcgccg
     4861 agggcgactt cggcgtgatg gtggcgctgc gcggcaccga catcgtgcgg gtgaagctct
     4921 ccgaggcgac ggccgagctc aagaccgtgc cgctggagcg ctacgccgag gccgaggtct
     4981 tcttcggcta ggcagcacga ccttcgggcg cttccggacg gaccctcgac ccgcccggaa
     5041 gcgcccgttg ccgtcttccc gcctgctgcc ggcagccggg ccggggaacg gccgaccgcc
     5101 cgttccccgc gcgacccggc cgggacggga gccgtgcggg gccgccggta cgggttcccg
     5161 cagcaccttc cggcgcgcgc cggccggaga tctcccgaac cgcttcgacg ccccgccgcg
     5221 tcgggtacga ccacgccgga ccggcccgga ccggtgcccg cacgcggtcg gacgagcctt
     5281 ggccaccggg tgcggcgcgc gctgcgggaa caggtccgcg acgggcgttg cgaccccacg
     5341 tcgcccggcg attcgccccc cgggcgggtg gtgggcatga cgcgcatcat gatgaggcga
     5401 tccagtgccc gtccctcagc gcggaccgcc tacccttaac acgtgaactg gaccgtggac
     5461 gtgcccgtgg acacgcttcc cgagctcccg cccctcccgc ccgagctccg caaccgactg
     5521 gacgaagcgc tgagccgccc cgcggcccag cagcccgaat ggccggacgc ggagcaggtg
     5581 cgccgggtgc gcgcggtgct ggaaagcgtc ccgccgatca ccgtgcccgc cgagatcgac
     5641 cggctgcgcg gcaacctcgc cgaggtggcc cgcggtgagg cgttcctgct ccagggcggt
     5701 gactgcgccg agacgttcgc ggacaacacc gagccccaca tccgcgccaa cgtgcgcacc
     5761 ctgctccaga tggccgtggt gctgacctac ggcgcgagcc tgccggtggt caagatcggc
     5821 cgcatcgccg gccagtacgc caagccgcgc tcgtcgaaca tcgacgcgct cggcctgccg
     5881 tcctaccggg gcgacatcgt caactcgctg atcaccacgc ccgaggcgcg cgtcccggac
     5941 ccgtcgcgga tgatccgcgc ctacgccaac gcgggcgcgg cgatgaacct gctgcgggcg
     6001 atgaccacgg cgggcatggc cgacctgcac cggctgcacg agtggaacaa ggacttcgtg
     6061 cgcacctcgc cggccggcga gcggtacgag gcgctggccg ccgagatcga ccgcggcctg
     6121 cggttcatgt cggcgtgcgg cgtgcaggac agctcgctgc acaccacgga gatcttcgcc
     6181 tcgcacgagg cgctcctgct ggactacgag cgcgcgctgc tgcgcctgga cagcaacagc
     6241 gaccagccca agctgtacaa cctgtcctcg cacttcctgt ggatcggcga gcgcacccgc
     6301 cagctcgacg gcgcgcacat cgcgttcgcc gagctgctgg ccaacccgat cggcctcaag
     6361 atcggcccgt cgaccacgcc ggagatggcg gtcgagtacg tcgagcggct cgacccgcgc
     6421 aacgaggccg gccggctgac cctgatcagc cggatgggca acggcaaggt gcgcgacgtg
     6481 ctgcccgcga tcgtggagaa ggtcaccgcg tcgggccacc aggtcatctg gcagtgcgac
     6541 ccgatgcacg gcaacaccca cgagtcgtcc accggctaca agacccggca cttcgaccgg
     6601 atcgtggacg aggtgcaggg cttcttcgag gtgcaccgcc ggctgggcac gcaccccggc
     6661 ggcatccaca tcgagctgac cggcgaggac gtcaccgagt gcctgggcgg cgcccaggag
     6721 atctcggaca ccgacctggc gggccgctac gagaccgcct gcgacccgcg gctgaacacc
     6781 cagcagtcgc tggagctggc cttcctggtc gcggagatgc tccgcagctg acctgatcgg
     6841 acccgacccg cgcccggcgg cccaggaccc cacgtcccgg accgccgggc gctgtcgtct
     6901 ccggggccgc tgtcgttccg ggcgctgtcg tcgcgggcgt cgccctcgcg gcggtgcggt
     6961 cgaccgccgc gctcgacctc cgcgcgccgg gccgcccaga aggccgcgtc ccgcccgccg
     7021 acggccacgc cggtcccgcc gtcgagctgt tcgcgcaggt tgtccggcgt gccggttgat
     7081 ctcggtgagc cggtgcggca ggacgtcgaa cagcgtcacg tccgggcgcg gccaccacgg
     7141 cacgtgacca ggtgcgtcga acgcgtcgac cgtcgcggcc gagtgcgccc acacccgccg
     7201 gtagcgctcc acgatcccgg cgcgggtctc gtgctcggtc gcccacaggt cggtgccgcg
     7261 cgcggtctcg tcgtcccagc ggggcagcgg ctcggggaac ggccggccga agacctcgcc
     7321 cgaggtagcg ggcctccgac gtcgcctcgt gctcgaccag gccgagcacg aggccgcccg
     7381 ccgtcagacc gcgatgatcg tgatcttggt gcccttcggc acccgctcgc cgggccggat
     7441 cgactggttg atcaccgtcg cccgctcccg gttgttgaac tgcacctcga cctggaagcc
     7501 cgccttctcc aaggtctcct tggcctccct gagcttcttg ccctcgacgt tcggcacggt
     7561 cacgccccgg tccgccgcga cgatcacggt gacccgcttg tccgcgccga gcgtggtgcc
     7621 cgccaccggg ttggtccgga ccacccggcc gccgtcgacc tcgccggagg gctcctcggg
     7681 gccctccacg gggtcgaacc cggccgcggc cagctccgcg aacgcctcgt ccttcgtctt
     7741 gcccttcacg ttcggcaccg gcttgggctg cacgcccttg ctcagcacga ccgtcacgac
     7801 gctgccgatc tccacggccg tgccgggcgc gggcttggtc gtcacgacct tgcccttggg
     7861 cacgcggtcg ctgaacgcgt cgtcgttcgg gtcgagcttg gacttcagcc cgaccgcggc
     7921 gatctcccgc tccgcggcgg ccgggtcgga gcccgccgcc acctgcggca cgaccggctt
     7981 gccacgcgag accaccaccc gcaccaggtc gccgcgggtg gcctcggcgc cgggggccgg
     8041 gtcggtgctg agcacctggc cgctgggcac ggtgttgctg ttctcggtgg acaccgcgga
     8101 cttcaggttc gcgctctcca ggatcgcgac cgccgcgtcc tgctccttgc cgaccacgtc
     8161 gggcaccgac tcgacccggc cgatggacag ccaccagctc accaggccga ccacgaccgc
     8221 cgcgaccgcg acgacgctga tccaggtgat gaactgcttc ttgctcttgg cccgcatctc
     8281 ctcgtagagc tgctcgggcg tcttcttctt cggaggccgc ttcggtcgca cgggccgcgt
     8341 gcggggcacc acggccgtct gctgccctcc caggggcgcg ggaacgccca tggcgggcga
     8401 cggggtgggg tcgagcccgc gcggcaacgc ctgggtgccc tgcgggccgg gcggcgggaa
     8461 ccggcgcacc ggcacggtcg cctcggcgaa ggccacggcc ccgacgccca ccggctgcac
     8521 ccgctcggtc ttcggctcgg ccgacgcggg ggtgtcggcg gtcgccgccg tcacggtcgg
     8581 cacgtccacg gcggccaggc cgagcgtcgc ccgcgccgtc tccacctcgg acaggaacgc
     8641 ctcggcgtcc gccgggcgca ggaacggctc cttgcgcgtc gaccggcgga ccagctccgc
     8701 gacctcggcg ggcacgccgg tcaccggcgg cacctcttcg ttcacgtgcc ggtaggcgac
     8761 cgagatggcc gtgtcgccga cgtaaggcgg cgcgccggtc agcatctcgt agagcagcac
     8821 gcccgccgag tacacgtcgc tgcgggcgtc ggcgttgccg ttggtgacct gttcgggtga
     8881 caggtacgcg actgtgccga ggatcgtcgt gtcgctcgtg atggccggcg tggacacggc
     8941 gcgcgccagg ccgaagtctg cgaccttcac cacaccggcg cgcccgatga gcacgttctc
     9001 cggcttcacg tcccggtgca cgagcccggc ccggtgcgcg gcggccagcg gcgagagcac
     9061 ccgctccagc accgtcagcg ccagcggcac gtccagcttc ccccgggcgg tgatcaggtc
     9121 gcgcagcgtg ccgccctcga ccagctccat caccaggtag acccggtcct cgtccacgcc
     9181 ctggtcgtgg accgcgacga caccggggtg gtgcagcccg gccgcggcgc gcgcttcccg
     9241 ctcgaaccgc gcgacgaact gcgggtccga ggagaaccgg gggtccatga ccttgatcgc
     9301 cacggggcgc tccaagcgcg tgtcgacgcc ccggtacacg gtggacatgc ccccgcgtgc
     9361 caccagggtg cccactcggt agcgttgttc gagcagcccg ccgatcacgt tcgtcgccga
     9421 cctttccaca gccgtggatc gtacggtggg gtggagccga ccggagccgt gcgctgggag
     9481 catcccgacc ggcgtgtggg atccgtgtca aagcccccgg aaacaggggg tgtccgggaa
     9541 ccgacccggg ggtgtaccgc caccacccgg ttggcgcagg gcattgctcc cggcgttgtg
     9601 gcatcgtgac gcacgtgagt gcgattcctg ccgctgcgga tgtgctggct cccgacctgg
     9661 aggtccttga cctgcctgag gtcggcgagc gtcttggcct gccggtcacc cgtgtccacc
     9721 agttgctgcg cgacggccag ttgctcgcgg agcgccggaa cggtgtcctc gtcgtcccct
     9781 cccagttcct cgccgccgga ggcgtggtga aggggctgcc cggcaccatc acggtgctgc
     9841 gcgactccgg ttactcgacc gatgagatcc ttcgctggct gttcaccgaa gacgacacgc
     9901 tgcccggcac gccgatcgag gcgttgcgcg gcgaccgcgg ccgcgaggtg aagcggcggg
     9961 cacagtccat gggcttctga ctcgtgcgcc gaccagacca ctaactccga ccaggcgcgt
    10021 ccgggcggtt ccagcggagc cgtccggacg tcgcgcgggc cgccaccgac cgggacagcc
    10081 ccggcagggc gaccgagagc cgccgtgcgt tcgacaccac cacgcgcttg tccagcacgt
    10141 ggtggtcggc gacggctatt ccgtccagga tctcccggta gagcaccagc gccgtgcgca
    10201 cgcacggccg tgcgaccggg tgcagcagcg gcacggccgt ctccgcctcc cggtacgccg
    10261 cgtacgccac cgcggtgagg tgccgcaccg cgcgcctgat gcgttcgtcc ggcttgcccg
    10321 tgcgtcgcga ccacgccaac aactcccggt tcacgtcgta gacgcgcaac acgtcctgcg
    10381 gcaggtacac gcgaccgcgg tcgagatcct ctcccacgtc ccgcaagaag ttcgtgagct
    10441 ggaacgcgcg ccccaacgcc gccgcgcccg gctcggcgtg cgacaggggc gcgatggtgc
    10501 cgaagaccgg cagcagttgc agcccgatca cctcggccga cccgcgcatg taccggtcca
    10561 gctcggcgag cgtcgcgtac tcggtggtgt gcaggtccat ccgcatcgac gccaggaagt
    10621 ccgcgaacag cgcggggtcg atccggtagc gccgcacggt gtccgcgagc gccgccagca
    10681 ccgggtgccc ggtggggcgt cccgccagtt cgtcggccag ctgccgctcc agcacgtcca
    10741 gctcgcccgc cgggtcggcg gaggtgccgc tgtccacgat ctcgtcggcc caccgtgcga
    10801 agccgtacag ggcgtgcacg gcggggcgtc gcacgggcgg gagcagccgg gtggcgagga
    10861 agaacgtgcg gccgtggcgg gcgttgagct cacggcaccg ggcgtaggcg tcggccaggg
    10921 ccggcccggt cacgggtacc tgctggacag cttcagcggg tcgggcttga ccagggagac
    10981 gcacgccagc gccgagacgg cggcgatgag cgccaggtag ccccacgagt agagcgcggt
    11041 gtcaccgtcg gggaaggtca ccagcagcag gaacgtggag aagaacgccg ccgcctgcaa
    11101 ccccttggtg ctccaggcca ggccggccgc cagcaccagc gcccagctga agtaccaggg
    11161 cagcgtggcc ggcgagagca gcgccacggc cagcgacgtg atcgccgccc ggcggatcgc
    11221 ctccggcccg ccgtcggcgg cggcccgcca ctgccgccag gcgatgaaca gcagcagcag
    11281 cgacccgagg ccgcgcgcga cggtcaggaa cacgcccggc tcgacccgca ccaccaggtt
    11341 cacgacggtg tgggcgaagt caccgacggc gctgggcagc gacagccagt tgacgatggt
    11401 ggacgacgag ctcagcgccg ggatccagcc caggtcgagc ccggacagca gggtcgtcgc
    11461 ggtgaacacc acgaggaacg tggccagccc gcccgcgatg gccttgacca gctgcaccgt
    11521 ccgcgagccc gccagccgtc gcgcccacac cagcaccagg aacggcagcg cgacgacggc
    11581 ggtggccttc accgcgaacg ccagggtcac cacggcgatc cccagcacgt gccggccgtc
    11641 gagcacgaac aggcagccgg cggccatcag gccgaccatc agcaggtcgt tgtgcgcgcc
    11701 gccgatgagg tgcacgagca tcagcgggtt cgccgcggcc agccacagcg cgaccgcggg
    11761 ccggccgccg aggtggcggg ccaggccggg cagcgcccag cagagcagcg ccaggccgat
    11821 ggccagcacg aaccgcatca gcaccacgcc gccgatgacg ctcgcgtggg tggcccacac
    11881 gacgctcatg gcgagcacca ggaacaccgg gccgtacggc gcgggcgtgt tctgccagac
    11941 ccagctcacg ttgtccgaca gcgggctctg cagcaccgcc gggccgacct tgtacgggtc
    12001 caggccgttg agcgcgatct ggccctgggc gaggtagctg tagatgtcct tgctgaacag
    12061 cggcggcgcg aacagcagcg gcagcgtcca cacgacgatc gcggtcagca cggcgctgct
    12121 gccgacgtgc ccgttgcgga ccatgcggcc gagccggatc cacgaccaga tcaccaggcc
    12181 caggccgagg tagagcacgg cggtggccag gtcctggccg tggccgtacc ggatccagct
    12241 cagcgtggtg tcggcgagca gcgggtcgcg cttgagggtc gcccccgcgc cggtgccgcc
    12301 cagcgcgacg agcatgacgc ccgcgacgcc gagcaggatg gtccgcacgg ggatcccgcc
    12361 ggggtccgga acctgggtag caccggaccg caccggctcg acaggtgcgg cgctcgatcg
    12421 gggtggggac ggggtcgcgg ccatcgcggc aacatcgtcg cacaacgcga gcgcgcgtcg
    12481 gcacgctatg gcgggcacgc gtggcgggct cgtggcacct cgacggatcc tcgcacgtgc
    12541 gtctcacccg agcgagtgac cacatggagt attccgacgt gcgggaacac ccgttcgggc
    12601 gagttccgct gacggcctcc ggtcgtcctt tccggtgttg ttcgcaccga ccccgcgtct
    12661 cggttcgacc cggtccgagg gcggtgtccg gacgtcggtc cggagtgccc ccgatcacgc
    12721 caccgtcggc gtccgacggc gctctggtcc gcgaccaccg gtcaccgcgg gctgtgcgcc
    12781 cgcgtccgcg ccgccggtcg ccgccacgcc gcgccggtgg ccccggtgat ccgctgggcg
    12841 gccagcctcc cggagatcag caccggcggc acgcccacgc ccggcgtggt gccgcagccg
    12901 gccagcaccg cgttgtccag gaccaggttg cgcggccgga acggaccggt ctgggcgaac
    12961 gtgtgcgcgg ccgagaacgg cgtgcccgcg gccagcccca tgcccgccca gtccttcggc
    13021 gtgaccaggc gctcgacctc gatcgagtcg ccgaacccgg tcagcccgcg ggcctggagg
    13081 gtctgcacca cctcgtcccg gtaggccggg ccgacccgct cccagtccac cgggccgacc
    13141 cgcaggttcg ggaccggcgc gagcacgaac atgccgcgcc ccggcgggct ggtgaccagc
    13201 agcgacgggt cgctcatcag cgagccccgg cgggtcagct cgtcgaacgt gcggtcccac
    13261 gcgcggccga agaacaacgt gtggtgggcc agttccggcc acgtccggtc gacgcccgcg
    13321 tgcagcacga ccgccgacgg cgaccacgtg atcggcaccg ggcggcgcgg gcggtggccc
    13381 agcagccggt aggacatcgg caggtccggg gtgagcacca cggcgtcgca cgggatgcgc
    13441 tcgccctgcg tcgtgcgcac ggcggtgacc cgcccgccga tccgctccag ccacgcgacc
    13501 ttcgtccggt agcgcaggtc cgcacccgcg tcacgggcgg cgccggccaa cgcgtcgggc
    13561 agcgcgcgca tcccgccacg cgggtagtag acgcccgcga tcgtgtccat gtacgcgatc
    13621 acggcgtacg cggcgagcgc cttgcgcggc ggcacgcccg cgtagagcga ctggaacgag
    13681 aacacccgct ggagccgctc gtccttgagg aaccgcgcca ccgacgggcc cagccgggcg
    13741 aagccgcgca gcgccgccag ccgcgccagc cggggcgtga gcagcccgat cggcgagtcg
    13801 aagttcgcgc cgatgaacgc gtccttctcg acccggtaga gctcggtcag ccaggaccgc
    13861 agcgcccggt agccggccgc ctcggcggga ccggcgaacc gccgcacctc ggcctccatc
    13921 gcgtcgccgt cggcgtgcac gtccagcacg tcgccgtcgg cgaaccgcgc ccggtaggcg
    13981 ggctcgacgg gggccaggtc cagccggtcg gccaggctct cgccgaccgc gtccagggcc
    14041 tcgtccacca gctccggcat ggtcagcacg gtcggcccgg tgtcgaaccg gtagtcgccc
    14101 aggtccagcc gcccggcccg gccgccgggc aggtcgtcgc gctccacgac ggtgacccgg
    14161 cggcccgcgc cgagcaggtg cagcgccgcg gacaggcccg ccaagcccgc gccgaccacg
    14221 acgacgtggt cggtgcggcc ggtgaccgtg cgcatggtca gtaggtccgt ttcgtggcgc
    14281 tgatcgcgag ttcggccagc cggtccccgg cggggtccgc gaccggcgcg tcggccagcg
    14341 cggccagcgc cgactcggtc agccgggcga tccggtcctc gaccgcggcc accgcgccga
    14401 cctcgaccag ccgggcccgc acctcgtcca cctcggccac gtcgaggtcg ggccggccca
    14461 gcgcgtcgtg cagcacgtcc gcgccgaact ccatgcccag cgcgaccagc agggtccgct
    14521 tgccctcgcg caggtcgtcg cccgcgggct tgccggtcac cgccgggtcg ccgaacacgc
    14581 ccagcaggtc gtcgcgcagc tggaaggcca cgccgatgtc ggtgccgaac gcccgcagcc
    14641 ccgccacgag ctccggcgac gcgtcgccga tcgccgcgcc catgtgcagc gggcgctcca
    14701 cggtgtaggc ggcggtcttg agccggtcga tgcgcagcgc ggcgtcgggc gaggcgtcgc
    14761 cgcgcgcctg ggtgagcacg tcgaggtact ggcccgcgag catctcggtg cgcatgtccc
    14821 gccacggcag gctcagccgc tgcaacgcgt cgttgggcag cccggcggcg aagagcatgt
    14881 cgtccgccca ggccagcgcc acgtcgccga tcagcaccga ggcggccagg ccgaaccgtt
    14941 cgggctcgcc cagccagccc tcggcgaggt gccggcgggc gaaccggacg tgcacggtcg
    15001 gcatcccgcg gcgggtttcc gaagcgtcca tcaggtcgtc gtggatcagc gcgcaggcct
    15061 ggatcagctc cagcgagctg accgcggtga gcaccggtgc ggccagctcg ccgtccgggt
    15121 cgccacccgc cgcccgccag ccccaccagg cgaaagtcgg tcgtatccgc ttgccgccgc
    15181 cgagcacgaa gtccgccagc gcgtcgacgg caccggtgaa gttctcctcc atccgcccgc
    15241 ccagggcgcg gcggtcggcg aggtagcctg cgagcgccgc gtcgacgtgc ttgggcagtt
    15301 ccaggtccaa cgggtggggc gacaccctcc tatggtcacc tctgccccgc ggcgcccacc
    15361 agccgggggt ctgctcccat ccagtgaacc gttcctccca cgggccggca cgggcactag
    15421 gctggtgggc atgacgtcgg tcgtcgaacg cctcagcggc ggcaccccgg tgttctcggt
    15481 cgagttcttc ccaccgcggg acgacgccga cgaacaggtc ctctggcgtg ccatccgcga
    15541 actggagggc ctggaccccg ccttcgtgtc gatcacctac ggcgcgggcg gctcgtcccg
    15601 cgaccgcacg atccgcacca ccggccgggt ggtccaggag acgaccctgg tggcgatggc
    15661 gcacctcacc gccgtgagcc actcggtggc cgagctgcgc aacgtgatcg gctggtacgc
    15721 ggcggtcggc gtgcgcaaca tcctcgcggt gcgcggcgac ccgcccggcg acccccacgg
    15781 cgagtgggtg ccccacccgg acggcctgac ctacgccgag gagctcgtcc ggctgtgccg
    15841 ggaactgggc gacttctgcg tgggcgtgtc cgcgttcccg tacgggcacc cgcgctcggg
    15901 cgacctggac accgacctca agcacctgat caacaagctg cgcgcgggcg ccgacttcgc
    15961 gatcgcgcag ctgttcctgg agccggagca cttcctgcgg ctgcgcgacc ggatcgccgc
    16021 gctcggccac gagacgcacc tgctgcccgg cctgatgccg ctgaccacgc cgcgcacgct
    16081 ggccaagtgc gtggagctgt ccggcgcgcc gctgccggtg tcggtggccc ggcggctgga
    16141 gccgctggcc gacgacccga aggcgttccg gtcggccggg gtcgacctgg tcaccgagat
    16201 gggggagcgg ctgctcgccg aaggcgtgcc ggcgctgcac ttctacacgt tcaaccgctc
    16261 caaggcgacc cgcgaggtgg tgggccggct gggcctggtg cccgcccgga cctgaccccg
    16321 gcccggtgcg gccgggggtc aggcgcggcc ggagggccgg cgccagccgg gggtcagtgc
    16381 agccggcgct cggtggccga gtccagcggc acggcgaccc ggttgaaccc gttgatcgcg
    16441 atcagctggg ccagcagccc ggcgacctgt gcctggtcga acgtcgcggt gaccttcgcc
    16501 cacagctcgt cgggcacgcc gtgctcgccg agccgggtca ccgcgtcggt gaactccagc
    16561 gcgacccgct cggtctcggt gaagaaccgc gactcgtgcc acaccgacac ggcgaacagg
    16621 cgctgcgggt tctccccggc cttgatcgcg tcggtggagt gcatgtcgac gcagtacgcg
    16681 cagttgttga gcatcgacgc ccgcagcttc accagctcga tcagaccgtg gtcgaggtgc
    16741 tggtgggcgt agccgtcgat ctggagcagc gcctggtaga cctcgggcgc gacttcggcg
    16801 agattcatcc tcatacccgg tggacgacgc ggcccgccga ggtgtgacag cgcccgacgt
    16861 acgccccgtc acaccgggac cgggtgctag gcgaccaggc tccggcggtg cgcgacgatc
    16921 gccaggacca ccacgatcag cgccgccgcg ccggtcaggc cggccaccag catggtccac
    16981 ccgaagtacg acggcgagtt ctccccggcg tagcggaggg tggcggtgag catcgacgcc
    17041 tggccgggct tgggcgacca cgcgatcgtc gtcgactcct cttcccgccc gttcgtgtcg
    17101 acgacctcac ccggaaagct gatcttgatc tggatgtccg cgcggtcggt cggcacctgg
    17161 gtgaggtcca ccgagccgga cagcgtcacc aggtcgccgg agcgccggaa ccccagctgg
    17221 taccggctgg acgacgcgct ggtcgccatc gacagggtcc gcacctcctc gaaggtgagg
    17281 gcgctgaaga acagctgggt cccggtgtag ttgtccacct tgtacggctt ggtggtcacc
    17341 cgtccggcca gctcctcggg caccctgagc tgcgggcccg ggtcgttgtc ctgggtgggc
    17401 ggggtggcgg cgacgatctc gccggagacg cggtcgtccg gcgacaccgc catcgcggcg
    17461 tgcagccgga tgcaccccgt cagcgcgaac atcgcgagca ggatcaccgg caggaggagc
    17521 gctgaggccc ggggcacgcg ggtcatcctg ccggccgggt caaaagttga ccgtccggac
    17581 acggtcgtga gcgtggctaa ttacctgttg gaggtacatg acccacgggt aacgtgccgg
    17641 acatgtcacc ctctccggcc ggcgtgcacg gcatcagcaa ccagttcgtg gccgattacg
    17701 cggcggccga cccgttgacc gcgacgttca tcggcacgcc cggccacgac gaccggctga
    17761 ccgactactc gcccgagggc cacgccgccc gcgaagaact ggccacccgc gccctggccg
    17821 acatcaccgc cgccgagccc gccgacgccg gcgaggccgc cgccaagtcc gtcttcctgg
    17881 agcgggtcgg gctggacgtg gagatccacc gggccggcct gtgggagggc gagctcaacg
    17941 tgctggcggg tcccgtgcag agcctgcgcg aggtgttcga cctgatgccc acctcgaccg
    18001 ccgaggactg ggcgacgatc gccaagcggc tcaccgccat gccggaggcg gtggcgaacc
    18061 tgcgcgcggg cctggcccac tccgccgaca agggcaaggt cgccgcgctg cggcaggtcg
    18121 ccaaggtcgc cgagcagtgc gacacctggt cgggccggtc cggtggcaag tcgtacttcg
    18181 cgacgctgat cgagcaggcc gacgtcgaca cgtccctgcg caccgacctc gaagccggcg
    18241 cgaaggccgc cgccgaggcg tacgcggacc tggccgcgtt cctgcgcggg gacctcgcgc
    18301 ccaaggcgcc gaagaaggac gccgtcggcg aggacgtcta ccgcctgtgg tcgcgctact
    18361 tcaccggcgc gcggctggac ctggccgagg cctacgagtg gggctgggcc gagttcaccc
    18421 gcatcgagac cgagatgaag caggtcgcga accggatcaa gccgggcgcg accctcgccg
    18481 aggccgccgc cgcgctggac gcgaacccgc gctacctggt cagcggccag gccggcctcc
    18541 agtcgtggat gcaggacctc tccgacaagg ccctgctcga cgtccgcgac gtgcacttcg
    18601 agctgcccga cgagctgatg aagctggagt gccggatcgc accgcccggc ggcggcgtcg
    18661 gcgcgtacta caccggcccc accccggact tcgcccgccc cggccggatg tggtggtcgg
    18721 tgcccgcgga caagaccgag ttctccacct ggcgcgaggt caccaccgtc taccacgagg
    18781 gcgtccccgg ccaccacctg caggtcgcca ccgccgtcta ccaggcggag aagctgaaca
    18841 acttccagcg gatgatgtgc tgggtgtccg gccacggcga gggctgggcc ctctacgccg
    18901 agcgcctgat gcgcgagctg ggttacctgg aggacgacgg cgacctgctc ggcatgctcg
    18961 acgcgcacct gttccgcgcc gcccgggtga tcatcgacat cggcatgcac ctggagctgg
    19021 agatcccgaa gggcgcgggc ttccacgacg gcgagcgctg gaccccggag ctgggcctgg
    19081 agttcatgct cacccgcacc atcaccgacc cggcgcacgt gcacgacgag atcgaccgct
    19141 acctgggctg gcccggccag gccccgtcct acaagctcgg cgagcggctg tggctggcgg
    19201 cccgggacga cgcgcgcgcc cggcacggcg cggcgttcga cctcaagacc ttccacaagg
    19261 acgcgctgga gatgggtgcg atggggctgg acacgctgcg ggagcgcctc gcggaactgt
    19321 gaacggccaa gcggtgaaca ggccccggtg agtccgcttc acggcgtcgt caccggggtt
    19381 tctgttgcat atgctgcggg cacgagtgtg aggggggacg gatggccaga cgtctcaggc
    19441 gttcggcgac ggcgctcgcc gccgcgggcg cgttggtgtt gggcgcggtg ctcggcgcgg
    19501 taccggcgca ggcgcaggaa cacgcgcccg acgagtggcg gatccggctg gagatcgtgg
    19561 actacgcgtt cagccagatc ggcgcgaagg agaacggccc caacgggtac ccgcagcgct
    19621 accaggacgt ggaccaggac gtccggcgtc ccgtggagtg gtgcggcgtg ttcgtgaact
    19681 gggcgtggac caaggccggt gtgccacaac gcccgtcgat gcgccccgcc gaaggcgcgc
    19741 cgggcgtcga ccagggccac tgggcgacgt actggcagaa gtggggccag cagaacagcc
    19801 gctggaagcc cctggccgac cgtgacgtgg agatgggcga cgccgtcgtg tacggcaact
    19861 acccgtcgat ggtcgcgcac gtcggcatcg tcgtggaggt cagctacgac gccaccggcc
    19921 agaaggcgac ccacgtccgc acggtcgagg gcaacgtcag cgacaaggtc gtgtactcga
    19981 agtggcgcag gctctcggac ctgaacgccg gccccggcct caaagcctcg ggcttcgtct
    20041 caccgttcta gctctcccgc tccacacgcc acgggcggcc gtcgaccaca acggccgccc
    20101 gttgtcgatc cgcgcccgca aggtgtcggc tcggtcgtcg gcaggctgcg ggatgtggtg
    20161 cggcagcagg ctgtcggtcc cgacgcggcc agggcgcggg agtgcagtgc gcgcaccgag
    20221 tccgcgaacg tcggcgggtc cgccacgacc gacgccaaca gctccggcaa cagggatgcg
    20281 gtccggttcc ttcgcggcga tccacgtcgc ggtccccggt gtggcggtgc gcgtgctcgg
    20341 tcgacgtctt gccgatccgc ccgtcccggc gatcacccgc accaccggcg gaggtcagtc
    20401 caacggcagg gtgcggccca gcacggcgaa cggtcggggg tcgccggtga actggtagtg
    20461 ccgcagcacg tcggcgaagc ccagccggcg gtagagccgc catgccttgc tcggcccttc
    20521 cggcgtggac agcagcacgc gggacgtcgg aacgcccgcc agcaggttgc gcagcaggcc
    20581 ctcgccgatg ccgcggccct gctcggtcgg caggacgtgc agttcggtca gctcgaagta
    20641 gtcgcgcatc cactcctcga ccgagttcgg cccggagacc agggtcaggc cgtgccgcac
    20701 ctgctcgtgc caccactggc ccaccgagcc gcggtagccg tagccgatgc cgatcagctc
    20761 gtcgtcctcg ccgagcgcca ccacgcaccg ccagccgtcg cgcagcatgt gcgccaacca
    20821 catcggcgcg cgctgctcgg ccgtgcccgg cgggtagttc atcgcgttga cgtagagcgc
    20881 cagcgcctcg ccgagccggg agttgagctc ccgggcggac agctccacca gccgctgcga
    20941 cggcgcggcg gtcatcgcgc gaccttcgcc ggggtgccac cggtcaggtc gaccagaccc
    21001 gcacaggtcg tcgggaacac cgcgtgcggg tgcccggcgg cggcccacac caccgcgtac
    21061 tgctccaggt cgacgtcgac gaacgtctgg atgggagccg ggtggcccag gggtgacacg
    21121 ccgccgatga cctggctggt gtgctcccgc acgaagtccg gcttggcgcg gtcgatccgg
    21181 tccgcgcccg cgagtccggc cagcaggtcg gtgtccgccc ggtgcgcgcc ggaggtgagc
    21241 accagcagcg gggcgacctc gtcaccgcgc acggcggcga acagcaggct gttggcgatg
    21301 gcgccgacgg gcacgtccac cgcctgcgcg gcctcggccg cggtgcggac ggcgtcggcc
    21361 aggacgcgga tcccgtccgc cgcctcgggg tggccggcct ctgccaaagc cgccgccacc
    21421 ttgcggatgc cggggtggtc aagtgcgctc acctgttcat gagaccacgt gcggccgggt
    21481 tgaggagtgc cgggttcacg ggttacgctg agcctgctcg aacatctgtt cgagctatgc
    21541 cttggtggtg gggcggggga agcgccccac caccaagtgc cgccgtctcc ccgcggcggt
    21601 cgtcgctgtc ccgacgccgc gaggaggccg ccgatgtcga cttccaccga cttccccagc
    21661 acccaccggg tgccgctgcc gctgcctccg gcgtcggccg tcagcctgct cgcgcaggcc
    21721 cgtgactgcg cccgggaagc cgagcgcgcg accgagcccg ccgaccggtt cgccaccgcc
    21781 tacctgggtg cgatgcgcgc cgccgcggcc gtgctggccc tgcgcggccg accgcaccgg
    21841 ggccgggcga ggccgaccag cgtgtgggtg ctgctgcccg cgctcgcgcc ggaactgcgg
    21901 gagtgggccg cgtacttcgc gtcctgctcc gcgacccgcg cggccgtcca ggcgggcatc
    21961 acccggcagg tagaccgacg gggtgccgac gacctggtgc gccaagcggc gcagttcacc
    22021 gagctggtcg acgagatcat gtacgagggc agactgtgag caggggactg gtcggctacg
    22081 gccggctgat cgacgtggtg gcggcggagg ccgagttgct ggcggcgtcg gcgcaggggc
    22141 agcgaccgga gcgccaggtg gccgcgtgcc cggggttgaa cctgggcgag accacgcggc
    22201 acgtcggcag catgttccgg atggtcgcgg cgtgggtccg cgaagggcgg caacccgttg
    22261 cctggcaaca ggacccggcg ccgggccaga cgctgtcgga ctacctgagg gacggcgtcg
    22321 ggccgttggt ggacgcgttg tccgaacgcg ccgccgacga cccgtgcgag acgtggtggc
    22381 ccgccgagcg cacctgcggg ttctgggcgc ggcggctcgc gcacgaggcg accgtgcacc
    22441 ggctggacgt ccagtcggcg gccggcctgc cgctggaccc ggtgcccgac gacgtcgccg
    22501 aggacggcgc ggacgaggtg ctgtcgctgt ggctgggcca ccgcctggac gtgctgggcg
    22561 tgcgcggcac ccgggagagc acggtcgcga tccgcaccgg ccgccgggtg tggatcgccc
    22621 gcaccgggcc ggagcccgcg accgcgtggc aggcctcgcc ggaggaggcg gaatcggccg
    22681 acgcggacgt caccggcccg cccgcgctgg tctaccgctg gctgtggggc cgcatcccgg
    22741 accgcgacgt ggagaccacc ggcgaccacg acgcgatcgc gcagctctgg gcgttgctgc
    22801 ggttggcgac caagtgacta gagggtgagg ttcgcggtct ccaccaggcc gtcgtcggtg
    22861 gcggtctcca ggcggtagcg ggcgttgcgg ccgatgatct ccaggaccgc caccgagttg
    22921 ccgaagtgcg gtccgctgac ccgctgccac gagaccgggt cgggcgacac gcccgcccgg
    22981 tccgcccaga accgcagcac ccgcgccagc ggcttcgacc acgacagccg gaacaccacg
    23041 cggaagatct tcggcgggtc gttgtgcacc ggcgagcaga ccagttgcag cacctgggac
    23101 ttcgtcggct cggcgaactc ggcgcgcgcc gcgtagctgt ggtggacgtc gccggagagc
    23161 acgcagatgg tgcccggcgc gtccgccgcg ccgcccagcc ggtgcagcag ccgcgcgagc
    23221 cgctcgaacg acgcccggaa cgccggccag tgctccaggt cgcccacctg gcggatcttc
    23281 tcgccgagcc ggccacgcca accgggacgg gccgcctggc gttcgttgag ggactggaag
    23341 tggctcagcg cgtgcggcat cagccacggc agcgacgagc cgatcagcag gtggtcgacg
    23401 tcaccctcgg cgttgcgctc gatccagtcg aactcctcgt cgcccaccat cagccgctcc
    23461 ggtccgtcca ggatccggcc gctgcgggtg tcgatgacca gcaaccgcac ccggccgaag
    23521 tcccgccggt agctccagcg ggtcgacttg cggccctccg cctcgcggtc ggcctgctcg
    23581 gcgaagtcct ccagcagctg ccgcacgtcc tcgccgccgg cctcccgcac ggccgtgaac
    23641 agctcgctgt cggcgagttc ggcgggcccc aggttgccga tgtgctggta cacccagtac
    23701 gaggccagcc cggcccggat ccgctcccgc caccagggct tgtccgccat ctccgcgcgc
    23761 cacgtcccgg aggtgttcca gtcgtcccgg atgtcgtggt cgtcgaagat catcgaggtc
    23821 ggcagcaccg acatcagcca gcggatctcc gggtcggccc acgactcgtg gtagagctcg
    23881 gcgtactcgc ggaacgacac cacctcgccc tccggctcgg gccgccgccg cgccagccat
    23941 tcccggacct gcggcgtcgg ctcgtccgcg tacacctggt cgcccagcag cagcagcgcc
    24001 cccggccagc ggtcctcggg ccagtccttc atccgggtgg cgaacgcgtc cagcgcgtcc
    24061 ggccccagcc ggtcggtctc ggcgccgccc ttggccgcgc ggcacgaccc gaacacgatc
    24121 cgccgcacgc ccccggtgcg gatcctcggc gcggggaagg cgtagtccgg ctccggccag
    24181 accacccggt cgtccagccg cacgtcgtag ggcgtggacg tgccgggcgt gagcccttcc
    24241 acgacgacca gcgcgaagtg ctgttccgcc acccggaacg tcgccgcgcg gtgccccgcc
    24301 acggtgacct cgcaggccgc gtcggtctcc acccagatcg tggccgacgt ctcgtcgacg
    24361 tgccgcagca ccggaccgag caccaattgc gccatgggcg cagacgttac cttcggacca
    24421 tgacaacgag gttgaccgat gtcgtggtgg actccgccga cccggccgag tcggcggagt
    24481 tctggtcggg gttgctggag cgcccggtgg tcgaccggac cgccgacgcg gtggtggtgg
    24541 cgctggacgg gtcggcgaac ctggtgttcg tgcccgtcgc ggagccgaag gtcgtgccga
    24601 accggctgca cctggacctg gtgacgacgt cgccgcagca ccgggagcgg ctgccggcgc
    24661 gggcccgtga gcggggcgcg gtgccggtgg acatcgggca gggggctgtg ccgtgggagg
    24721 tgttggcgga cccggcgggc aacgagttct gcgtgctgga accccgggac gagtacctcg
    24781 ggatcgggcc ggtcgcggcg gtggtggtca acgcggcgga ccccgtcgcg ctggccgggt
    24841 tctggtcgca cgccaccggg ctgccggtga cgcggcaggg ccctgggttc gcgtcgctgc
    24901 gccgggagga cgggttctgg ctggagttcg tccaggtcac cgagccgaag gtcgtcaaga
    24961 accggctgca cctcgacgtc gcgccgccgc cggacgggga cctggtgctg gaggtggcgc
    25021 ggctggaggc gtgcggcgcg gtgcgggcgg acgtcggcca gtccgtcgtg ccgtgggtgg
    25081 tgctggccga cccggagggc aacgagttct gcgtcctcac accccgttga cccggccccg
    25141 gagtgtccgg tcgcggcgac tcgaccccga ggttaccttc ggtgctcagc caaatgctga
    25201 gagtcacatc cttgggagga aaccgtgtcc ggaccgactc gtctccgcac cgccgccctg
    25261 gcgctgaccg ccctcgtcgc cgccaccctc gcgaccaccg gcctcacggc caccaccggc
    25321 cgagc
//
