LOCUS       NC_019693              22256 bp    DNA     circular CON 07-JUN-2024
DEFINITION  Oscillatoria acuminata PCC 6304, complete sequence.
ACCESSION   NC_019693
VERSION     NC_019693.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Oscillatoria acuminata PCC 6304
  ORGANISM  Oscillatoria acuminata PCC 6304
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Oscillatoriaceae; Oscillatoria.
REFERENCE   1  (bases 1 to 7689443)
  AUTHORS   Gugger,M., Coursin,T., Rippka,R., Tandeau De Marsac,N.,
            Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C., Tapia,R.,
            Davenport,K., Daligault,H., Erkkila,T., Gu,W., Munk,A.C.C.,
            Teshima,H., Xu,Y., Chain,P., Chen,A., Krypides,N., Mavromatis,K.,
            Markowitz,V., Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G.,
            Pagani,I., Pati,A., Goodwin,L., Peters,L., Pitluck,S., Woyke,T. and
            Kerfeld,C.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Finished chromosome of genome of Oscillatoria acuminata PCC 6304
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7689443)
  AUTHORS   Gugger,M., Coursin,T., Rippka,R., Tandeau De Marsac,N.,
            Huntemann,M., Wei,C.-L., Han,J., Detter,J.C., Han,C., Tapia,R.,
            Davenport,K., Daligault,H., Erkkila,T., Gu,W., Munk,A.C.C.,
            Teshima,H., Xu,Y., Chain,P., Chen,A., Krypides,N., Mavromatis,K.,
            Markowitz,V., Szeto,E., Ivanova,N., Mikhailova,N., Ovchinnikova,G.,
            Pagani,I., Pati,A., Goodwin,L., Peters,L., Pitluck,S., Woyke,T. and
            Kerfeld,C.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2012) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Oscillatoria acuminata PCC 6304
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: USA
            environment                       :: Missing
            num_replicons                     :: 3
            ref_biomaterial                   :: PCC 6304
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Missing
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly :: Newbler v. 2.3 (pre-release), VELVET v. 1.0.13, Parallel
            phrap v. 4.24 SPS
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi04162
            Funding Program                   :: DOE-GEBA 2009
            Gene Calling Method               :: GenePrimp, Prodigal 1.4
            Isolation Site                    :: soil
            Isolation Comments                :: isolated by MB Allen
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram-
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method :: Newbler v. 2.3 (pre-release), VELVET v. 1.0.13,
            Parallel phrap v. 4.24 SPS
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000317105.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 01:39:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,147
            CDSs (total)                      :: 6,067
            Genes (coding)                    :: 5,990
            CDSs (with protein)               :: 5,990
            Genes (RNA)                       :: 80
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 34 of 77
            Pseudo Genes (incomplete)         :: 37 of 77
            Pseudo Genes (internal stop)      :: 20 of 77
            Pseudo Genes (multiple problems)  :: 12 of 77
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:52:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6626794
            Orig. end                         :: 6649050
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003607.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086915
            Source DNA and Organism available from Cheryl A. Kerfeld
            (CKerfeld@lbl.gov)
            Contacts: Cheryl A. Kerfeld (CKerfeld@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22256
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="9"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..22256
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22256
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12256](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12256)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            8..148
                     /locus_tag="OSCIL6304_RS35485"
     CDS             8..148
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OSCIL6304_RS35485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_198017776.1"
                     /transl_table=11
                     /translation="MKTTQAKLETGLAQLDRGEGIDGEAVMAQLREKSRKLREEGQQLG
                     N"
     gene            336..1298
                     /locus_tag="OSCIL6304_RS25695"
                     /old_locus_tag="Oscil6304_5201"
     CDS             336..1298
                     /EC_number="1.1.1.169"
                     /GO_function="GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017716309.1"
                     /locus_tag="OSCIL6304_RS25695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5201"
                     /product="putative 2-dehydropantoate 2-reductase"
                     /protein_id="WP_015151314.1"
                     /transl_table=11
                     /translation="MDTALQSQRNRSYAIIGTGAIGGFYGAKLQQAGFEVHFLLHSDYQ
                     FVRQRGLRVDSVWGDFTLDSLNVYNDVHQMPPCDVVIVALKTTRNSLLTTLLPPVLKES
                     GAVLMLQNGLGNEEAIAPIVGPAHILGGLCFICSNKVGDGHIHHLDYGTITLGEYAPDY
                     QPLGITATLQDIAGDFEAAGIPIQFAEDLLLARWKKLIWNIPYNGLSVVLNARTDEIMK
                     NEYTRLLSEQLMQEVGAVAAAYNRKIPESFIQKMLDHTAKMKPYITSMKLDYDHHRTLE
                     IESIIGNPLQAAIAKQIPVPKIAMLYAQLNFINSQIQAK"
     gene            1368..2141
                     /locus_tag="OSCIL6304_RS25700"
                     /old_locus_tag="Oscil6304_5202"
     CDS             1368..2141
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017661949.1"
                     /locus_tag="OSCIL6304_RS25700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5202"
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_015151315.1"
                     /transl_table=11
                     /translation="MDERLIKPGLPQPPTFDRLRDERLYRKQRLAAAFRLFAHFGFDEG
                     VAGHITVRDPEFPDQFWVNPFGMYFGHIRVSDLVLVNHQGDILEGDRPINAAGFAIHSQ
                     IHQARPDVIAAVHAHSLYGKTWSTLGRLLDPLTQDACAFYGDHALFDDYTGVVLDVSEG
                     ERLARTLGNAKAIVLRNHGLLTVGHSVDEASWWFITMDRSCQSQLMAEAAGKPISIAPE
                     IAQLTYAQVGSHYMGWFSFQSLYDMIVRQQPDLLE"
     gene            complement(2203..2985)
                     /locus_tag="OSCIL6304_RS25705"
                     /old_locus_tag="Oscil6304_5203"
     CDS             complement(2203..2985)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045168.1"
                     /locus_tag="OSCIL6304_RS25705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5203"
                     /product="hypothetical protein"
                     /protein_id="WP_198017777.1"
                     /transl_table=11
                     /translation="MLVKDPLGEGEYSFGSYCVYRKLEQDVSGFKAAEKALFQTLKLSK
                     KEEERAGALVVGRFRDGTPITQFPTEQNVDPVPNNFNYDEDLPGVKCPFHAHIRKVNPR
                     GDKNDRHQTIEEQRQHRIVRRAISYGELPNARNHSLCVRSRFNNQLAHLQEMTRYPGED
                     EKVGLLFLCFQSDLFNQFMFMQKNWSNNYHFATYTTGFDALVGQGNPKKARQKWPNQWG
                     ENEVTEFDFYHFVTMQGGEYFFAPSISFLKTIASNFRE"
     gene            complement(3069..3840)
                     /locus_tag="OSCIL6304_RS33455"
                     /old_locus_tag="Oscil6304_5204"
                     /pseudo=""
     CDS             complement(3069..3840)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008492026.1"
                     /locus_tag="OSCIL6304_RS33455"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="Oscil6304_5204"
                     /product="IS1 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNSQPIQKSNDFEASQPVCPRCGSHNIRKNGHIHNGKQNHQCKDC
                     GRQFVQNNRKKYISNSIKKWIDKLLLERMPLAGICRVFEVSATWLQKYVNAKYAKVSRE
                     LEVSTKTPGKLIIECDELWSYVQNKQNQQWVWLALDLETR"
     gene            4165..4545
                     /locus_tag="OSCIL6304_RS34745"
     CDS             4165..4545
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /locus_tag="OSCIL6304_RS34745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_156823967.1"
                     /transl_table=11
                     /translation="MGSVIYQKRAWPVYWTFIDHTGASNLARQKAILTPIIRLLNGYKI
                     IVVGDREFHSVELAHWLQSKKVYFALRQKCNTYIKQSRKKGEDFESLSNLGLQPGMKLY
                     LPSVQFTKKKGFGRYALAVYWK"
     gene            4630..5001
                     /locus_tag="OSCIL6304_RS34750"
     CDS             4630..5001
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OSCIL6304_RS34750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_156823968.1"
                     /transl_table=11
                     /translation="MRMGIEAMFKDCKTGGYNLEGTGANQERLTRLVLLIALAYTASSI
                     QGVPIKQQGVQSCVARLTESGRSQRRHSNFWIGLYGLSWIDSLEKLQELSIEFMKLHPH
                     KRPFYRRGLRAMSLIQSSF"
     gene            complement(5450..7498)
                     /locus_tag="OSCIL6304_RS25720"
                     /old_locus_tag="Oscil6304_5206"
     CDS             complement(5450..7498)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017658628.1"
                     /locus_tag="OSCIL6304_RS25720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5206"
                     /product="S9 family peptidase"
                     /protein_id="WP_015151316.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.6e-65, bitscore:
                     219.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEKTSQPIAPKCLHVLSCHGDERIDNYFWMHDRNDPQLIAYLQ
                     AENHYTDLMMQHTKGLQERLYDEMSDRIEEAELSVPYRQGEFYYYWRTEAGKNYPIFCR
                     KQSSLDNREEVLLDCNELARGHRYFRLDLCEVSPNHQTLAYSIDTDGDENYTLCFLNLV
                     EGDRYAQSIPGVCSFVWKNDSQTCFYTQVDATSRSDKLFRYTVGNPISDRILIYQEFDE
                     TFNVFVSKTRSQSYILMEVISLLTSEIYYLENDNMNGKFKLIHPRSVEVRYKLEHHGDR
                     FYILTNEEAINGKLMQTLVDSPSRENWQTLIPEREGVNLEEISAFADRLVIYEREAGVK
                     KVRICQLSTGEEHWIEFPESVYEIKEDKNPEFNTENLRLEYKSLVTPDSIFEYNMSFRE
                     LTLKKQTTVPNGYDRTEYVSERIWAIAPDNEAIPISLVYKRGIEKNGKAPLLLVGYGAY
                     GVCEYISFCANRLSLLNRGVVFAIAHVRGGGEMGEKWHKDGKFLHRKNTFTDFIACAEY
                     LIKNKWTSQEKLAIFGESAGGLLIGAVLNMRPDLCKIAIAKTPFVDPLTSILDTTLPMS
                     VADWEEWGNPNNKIYYDYIKSYSPYDNVKQQEYPHLLITTGLNDANVPYWQPVKWTAKL
                     REHKTDDNIVSLKINEGAGHRGASGRYEKLKEVAFEYAFLADKWGLS"
     gene            complement(7618..8688)
                     /locus_tag="OSCIL6304_RS32675"
                     /old_locus_tag="Oscil6304_5207"
     CDS             complement(7618..8688)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015152095.1"
                     /locus_tag="OSCIL6304_RS32675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5207"
                     /product="IS630 family transposase"
                     /protein_id="WP_015147826.1"
                     /transl_table=11
                     /translation="MGARLRVFLTPEEDRTLFELRMATTLPQRVKDRASIVRLNAHGWY
                     VEKIASHFNWSVSRVRDTLHRWEKKGLGGLWDKAGRGSKAKWQDADIAYVEECLRQEPR
                     TYNSKQLAKKLAAERQVYLSPDRLRRVLKKKGIIWKRTRISHKNKQDPEERSIKQADLD
                     MLEFAAAAREIDLKYLDESGFCLWSSVGYTYFPKKEQKCQEQTRIRGRRLSILGIMQPK
                     IGFTYGLAIGSFTSKSYIKMMEIEAEEASKELALTGRIRVIVQDNGPIHKSLEVQNKWP
                     SWEEKGLYIFLLPKYCSEMNEIELEWQHLKRDELAGRMFEDELDLAYAVMAGVEARSVE
                     GNYTAKRVKFKSGPSP"
     gene            complement(8885..9988)
                     /locus_tag="OSCIL6304_RS25730"
                     /old_locus_tag="Oscil6304_5208"
     CDS             complement(8885..9988)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007353964.1"
                     /locus_tag="OSCIL6304_RS25730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5208"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_015151317.1"
                     /transl_table=11
                     /translation="MFDRYQIIDADCHVLEPIEMWQEYLEPAFKHRAPSPKMEIDGEKI
                     YFKISEELQQAGLSAILRDLHSYGISRYDSASQVQAVKAMGVEFCFLYPTMGLWLFAVD
                     TMAPQLAGAFTRAYNNWLRDFCSYDPHILRGVGAISLHDPEEMVSEVQRIAEFGWKAVF
                     LRPNPVKGRLLSDPAYEPFWAACEQLGIAVGIHEGTHSRLPATGADRFNTRFALHACSH
                     PMEQMMAMLALIEGGVLERHPGLRVAFLESGCGWLPYWLWRLDEEYELFGWEVKENVKM
                     KPSEYFRRQCFISVEPSEPYLEQAIDCIGADNLLFSSDFPHMDHRPEAIADLIAQSDRL
                     GDGTLQKIFWDNPSRFYGLNISSPVAV"
     gene            complement(10001..12256)
                     /locus_tag="OSCIL6304_RS25735"
                     /old_locus_tag="Oscil6304_5209"
     CDS             complement(10001..12256)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03882"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017721513.1"
                     /locus_tag="OSCIL6304_RS25735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5209"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_015151318.1"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 6.8e-19, bitscore:
                     66.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 4.5e-15,
                     bitscore: 53.9, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 3.2e-13,
                     bitscore: 48.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03882 (E-value: 6.6e-45, bitscore:
                     151.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.4e-93, bitscore: 311.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2.2e-79, bitscore:
                     265.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKKPMFKPQFRCETMPLEGVFLLSETDRFLLRGTPYTLLAPLLN
                     GNYTVTEIVDRLQDRLSVFEIYTLLDRLKELGYIIESTDSIPEDRAAFYQIQGIEPAIA
                     THRLQEIALSILSYGNIDPHPFATQLDSLGINCSDEGTFAVALTDDYLQTGLDACNRDA
                     IQRDRPWMLVKPVGVELWIGPIFIPGKTGCWHCLAHYLRGHRPLERYLQEHHQTENCLP
                     TAVAAIPATVQTALSIAATEIAKWAIASQHSRLEGQILTLNTLTWEQRYHKLWQRPQCP
                     CCGNPESLTIAHFAPIVLQSRPKSFTRDGGHRSHSPDYTYNTLADRISPICGAIATLQR
                     ISTWETPDGLTHSYRAQYPTVGTFPDLHHLQEGLRTEAYGKGRQDIQAKVSALCEAIER
                     YAGTFQGDEPRICSTLSNLDNGIHPNACMQFSARQFQNRTQLNGDRITFDWIPEPLDEN
                     AEIEWTPAWSLTHNQLRYLPTAYCYSGYSQQHQAYFTRADSNGCAAGNNLEEAILQGFL
                     ELVERDSIALWWYNRLRKPAVELSSFDEPYFDRLQEYYRTLNRDLWVLDLTADLQIPTF
                     AAISPRRDRHPENILLGFGAHFDPRLALLRALTELNQSLPAAFYGILDATTAYRDRDRE
                     GIDWWETATLANHPYLLPDSNQAPKTRPDYPHCWSDDLHTDILACVERVRAKGMETLVV
                     NQTRPDLSLSVVKVVVPGLRHFWPRFASGRLYDVPDQMGWVSEPLTEAQLNPLPAFF"
     aSDomain        complement(11963..12241)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OSCIL6304_RS25735_Goadsporin_CD_RRE.1
                     "
                     /evalue="1.50E-15"
                     /identifier="RREFam013.1"
                     /label="OSCIL6304_RS25735"
                     /locus_tag="OSCIL6304_RS25735"
                     /protein_end="98"
                     /protein_start="5"
                     /score="48.1"
                     /tool="antismash"
                     /translation="MFKPQFRCETMPLEGVFLLSETDRFLLRGTPYTLLAPLLNGNYTV
                     TEIVDRLQDRLSVFEIYTLLDRLKELGYIIESTDSIPEDRAAFYQIQG"
     aSDomain        complement(11972..12253)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OSCIL6304_RS25735_NHLP_CD_RRE.1"
                     /evalue="3.20E-21"
                     /identifier="RREFam015.1"
                     /label="OSCIL6304_RS25735"
                     /locus_tag="OSCIL6304_RS25735"
                     /protein_end="95"
                     /protein_start="1"
                     /score="66.2"
                     /tool="antismash"
                     /translation="LKKPMFKPQFRCETMPLEGVFLLSETDRFLLRGTPYTLLAPLLNG
                     NYTVTEIVDRLQDRLSVFEIYTLLDRLKELGYIIESTDSIPEDRAAFYQ"
     aSDomain        complement(12020..12241)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_OSCIL6304_RS25735_Cyanobactin_D_RRE.1
                     "
                     /evalue="2.10E-17"
                     /identifier="RREFam007.1"
                     /label="OSCIL6304_RS25735"
                     /locus_tag="OSCIL6304_RS25735"
                     /protein_end="79"
                     /protein_start="5"
                     /score="53.9"
                     /tool="antismash"
                     /translation="MFKPQFRCETMPLEGVFLLSETDRFLLRGTPYTLLAPLLNGNYTV
                     TEIVDRLQDRLSVFEIYTLLDRLKELGYI"
     gene            complement(12772..13140)
                     /locus_tag="OSCIL6304_RS25740"
                     /old_locus_tag="Oscil6304_5210"
     CDS             complement(12772..13140)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017721514.1"
                     /locus_tag="OSCIL6304_RS25740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5210"
                     /product="hypothetical protein"
                     /protein_id="WP_015151319.1"
                     /transl_table=11
                     /translation="MTITLQKKPAVNSPVECPQELRNAWARVFAHAWSQEDREFLRRLN
                     KDPRQTIEQIASGESSDSEQLCQACQTILEYVNDPNSEEGFLALPPLPEHLQRGNLSEE
                     QLYTYANQDGLYGVLRVC"
     misc_feature    13202..13216
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.09"
                     /tool="antismash"
     gene            complement(13274..13597)
                     /locus_tag="OSCIL6304_RS25745"
                     /old_locus_tag="Oscil6304_5211"
     CDS             complement(13274..13597)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017721515.1"
                     /locus_tag="OSCIL6304_RS25745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5211"
                     /product="hypothetical protein"
                     /protein_id="WP_015151320.1"
                     /transl_table=11
                     /translation="MDKTPYPPDLAHAWSRLFGYAWIPENREFLQGLRKDPKVTITNVM
                     NSGTPESIQGPCATILEYVNNDNCEYGYISIPTLPEGLKGLSEEQLYLYANQSELYGIM
                     RQS"
     gene            13945..15417
                     /locus_tag="OSCIL6304_RS25750"
                     /old_locus_tag="Oscil6304_5212"
     CDS             13945..15417
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017721517.1"
                     /locus_tag="OSCIL6304_RS25750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5212"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_015151321.1"
                     /transl_table=11
                     /translation="MSVDLTQTHIDPQDPIYQPLLEDLQANILKSHDRDYSAHLFLQFK
                     PNPDAVRQWIARFAKDRIVSAKQQLKRYNDLKTTSRSESSQLFVNFLLTYPGYQSLGFN
                     LTAGQLREFPSPAFKVGLAHFQTILDDPPVDAWEEGFQREIHGVVMLADNNWENLQTQA
                     QQILTELEEIAEIVNTEVGRVLRNSKGDAIEHFGFRDGVSQPLFFQPDLDDVAKQQGID
                     KWDPSAPLELVLVKDPLGEGDYSFGSYCVYRKLEQEVSNFKAAEKALAKALKLSKEEEE
                     RAGALVVGRFRDGTPLSLANAAQNADPVPNNFNYDDDLRGVKCPFHAHIRKANPRGDKN
                     DLHQTLEEQRQHRIVRRAISYGELPIARDKSLSVRSRFEGQLAHLKDMTRHPIADEKVG
                     LLFLCFQGDIFNQFMFMQKNWSNNQHFVSYTTGFDALVGQGNPKNLQQKWPQSWGKEGA
                     IDFDFYHFVKMKGGQYFFAPSISFLKTIDSQK"
     gene            15670..16776
                     /locus_tag="OSCIL6304_RS25755"
                     /old_locus_tag="Oscil6304_5213"
     CDS             15670..16776
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012264998.1"
                     /locus_tag="OSCIL6304_RS25755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5213"
                     /product="IS630 family transposase"
                     /protein_id="WP_015151322.1"
                     /transl_table=11
                     /translation="MPAPNHLSESQQEILLNELRENDSPLIRDRILILLLINDGKTYEQ
                     VAKFLQISYPTVAYWVKHGDPDKLESFKDGRAEGNHKKATKEYIDMLLDIIDKEPSKFG
                     YEFGRWTSARLAKHLEKETGIHLSESQVRRILKSKKYVFLWAKYSLEDRQNPLKRKAFK
                     NRLKEYLKIAKRYPKRLQVWFWDETGFSLRIVRRKQWTKRGKRKTVRGDRRKGRINVMG
                     CLRATDKKRINFFVETGCGESFYESLKSFYALVIQEWVEQGNSEEDFLEKGPKIVIILD
                     NASFHKRKDIAKLATEEMPKIFLEYLPEYSPDYNLIELVWHSAKEYIANKLFESISELE
                     SILHRLLNEGELIINWGRKIKNKGNQVY"
     gene            complement(16779..17291)
                     /locus_tag="OSCIL6304_RS25760"
                     /old_locus_tag="Oscil6304_5214"
     CDS             complement(16779..17291)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018884.4"
                     /locus_tag="OSCIL6304_RS25760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5214"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_052315802.1"
                     /transl_table=11
                     /translation="MTILFFGNPLMVNEETDYVKFLTTVNRTIFDNVVRMRSEKNLTLA
                     LLDYSDRTLTISGQHEEVLVVRTGGTVEQIDTMDLGFLIGLDTEIADFISQIQIELNPG
                     DAVVLYTDGITEAENLDGEQYGLERLCQIIGENWQLSPEEMRAAAIADLRRHIGEQKVF
                     DDKLSYI"
     gene            complement(17295..18521)
                     /locus_tag="OSCIL6304_RS33460"
                     /old_locus_tag="Oscil6304_5215"
                     /pseudo=""
     CDS             complement(17295..18521)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015163292.1"
                     /locus_tag="OSCIL6304_RS33460"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5215"
                     /product="ISAzo13 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MELTDSLKNLLKETASQLKGAQRRRFMAQTVIEMGYAGQSRAARE
                     LGWNRDIIRQGVRELETGITCVNNYQARGRKKTEIHLPNLLFDIKSIVDSQSQTDPTFQ
                     TNRLYRRLSASCVRKALIEQKNYRDEELPCLHRNNPDKIE"
     gene            complement(18581..18997)
                     /locus_tag="OSCIL6304_RS25775"
                     /old_locus_tag="Oscil6304_5216"
     CDS             complement(18581..18997)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025180.4"
                     /locus_tag="OSCIL6304_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5216"
                     /product="ISAs1 family transposase"
                     /protein_id="WP_044197969.1"
                     /transl_table=11
                     /translation="MSQIAIVQAFADLEDCRRQAGTRHKQSLCLALFTLGVAAGNRGFI
                     AIGDWLKAYHDELLELFKPEKNRLPSYSTIRRTLLRIEQQRYSACLSRFFGIDPIESET
                     IAVDGKVLLWYYEAINDEANVDSHPAIMLGSPKK"
     gene            19082..19342
                     /locus_tag="OSCIL6304_RS25780"
                     /old_locus_tag="Oscil6304_5217"
     CDS             19082..19342
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="OSCIL6304_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="Oscil6304_5217"
                     /product="hypothetical protein"
                     /protein_id="WP_044195992.1"
                     /transl_table=11
                     /translation="MDDGFILPLSENYTLIETDVEEVKEHLNIDYKFAHDRIQQAAYSL
                     IPETEKSSVHWQIGQLLLQNTPVNEQEVKIFALGRRFSTRA"
     gene            19417..20993
                     /locus_tag="OSCIL6304_RS25785"
                     /old_locus_tag="Oscil6304_5218"
                     /pseudo=""
     CDS             19417..20993
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015147653.1"
                     /locus_tag="OSCIL6304_RS25785"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="Oscil6304_5218"
                     /product="IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRPPLWHPPVELSDSEQVIINRIKKAKLFTFLRLNRLFIFDDEFQ
                     EELNTIFKDSTMGNCPIAPAQLALATILQAYLGISDEEVIEELVMDLRWQLVFDCLHCE
                     KPPFSKATLIRFRSALIKKALTNV"
     misc_feature    21771..21785
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.46"
                     /tool="antismash"
ORIGIN
        1 cgagtgggtg aaaacaactc aagcaaagct agaaacggga ctcgcccaac ttgatagagg
       61 ggaagggatt gatggagaag cggtgatggc tcaactccga gaaaaatccc gtaaactccg
      121 agaagagggt cagcaattag ggaattgaaa tagtccggat gatgagtggg tatcgcgatt
      181 taaactcact gctttctgat gccgacgagg gaaactaaat cagactaaca acagaaagag
      241 ttaaagaaat tgagagaaag agggaaaatt actatgttat tgatgccact tctccgctaa
      301 aatcgataga gtagcgagtt gaaagtcatg ggagaatgga tacagcattg cagtctcaga
      361 ggaatcggag ttatgccatt attggcaccg gggcgattgg cgggttttat ggcgcgaaac
      421 tccaacaggc ggggtttgag gtgcattttt tgctgcatag cgattatcag tttgtgcggc
      481 agcgcggatt aagagtggat tcggtttggg gggactttac cctcgactcc ctgaatgttt
      541 ataacgatgt ccaccaaatg ccgccttgtg atgtggtcat tgttgctcta aaaaccaccc
      601 gcaattcttt attgacaact ctgctgccgc cggttttgaa agaatcaggg gcagttttaa
      661 tgttacaaaa tggtctgggt aacgaagagg cgatcgcacc gattgttggt ccggctcata
      721 ttctgggcgg attatgcttt atttgctcta ataaagttgg agacggccat attcaccacc
      781 tcgattatgg cacgattacc ctaggggaat atgcaccgga ttatcaaccc ttgggaatca
      841 ccgctactct ccaagacatt gccggagatt ttgaagcagc cggaattcct atccaatttg
      901 ccgaagattt actcctcgcc cggtggaaaa aattgatttg gaatattcct tataatggct
      961 tgtccgtggt gctgaatgct cgaactgatg aaatcatgaa aaatgaatat acgcgccttt
     1021 tatccgaaca gttaatgcag gaagttgggg cggttgctgc tgcatataat cggaaaattc
     1081 ccgaaagttt tattcaaaaa atgctggacc atacggccaa aatgaagccc tatattacca
     1141 gcatgaaatt ggattatgac caccaccgaa ccctagaaat agaatccatc attggcaatc
     1201 ctctgcaagc ggcgatcgcc aaacaaatcc ccgtccccaa aatagccatg ctttatgctc
     1261 aattaaactt tataaatagt caaatccaag ccaaatagct tgtccccatt tcgtagtaaa
     1321 gacttcagtc gttcccgcat cttcccccta aaccaccccg caccattatg gatgaacgct
     1381 taatcaaacc cggactcccc caacccccca catttgatcg cctcagggat gaaagattat
     1441 atcgcaaaca acgcttggca gccgcatttc gcctattcgc tcactttgga tttgatgaag
     1501 gcgtagcggg tcatattaca gtccgggacc cagaatttcc tgaccaattc tgggtcaatc
     1561 cctttggaat gtatttcggt catattcgcg tctcggacct ggtattagtc aaccatcaag
     1621 gggacatttt agaaggcgat cgcccgatta atgccgctgg atttgccatc cattcccaaa
     1681 tccatcaagc gcgtcccgat gttatcgcgg cagtacacgc tcattccctc tatggcaaaa
     1741 cctggtccac cctcggacga ctccttgacc ctctcactca agatgcctgt gccttctatg
     1801 gggatcatgc tttatttgat gactataccg gcgtggtatt agacgtgagt gagggcgaac
     1861 gattagcgcg caccttggga aatgctaaag ccattgtact tcgcaatcat ggattactca
     1921 ccgtgggtca ttccgtggat gaggcaagct ggtggtttat tacaatggat cggtcctgtc
     1981 aaagtcaact gatggcagaa gcagcaggaa aaccgatttc tattgcgcca gaaattgctc
     2041 aattgactta tgctcaggtg ggaagtcatt acatggggtg gtttagcttt cagtcacttt
     2101 atgacatgat tgttcgtcag cagccagatt tattggaatg aatagggggg tggagagaag
     2161 aacccccagt tcaatccaat tttccgggtc ctttcttctc ccttattccc tgaaattgga
     2221 ggcaattgtt ttcaaaaaac taatgctagg ggcgaaaaag tattcacctc cctgcatggt
     2281 gacaaagtga taaaaatcaa attcagtgac ctcattttcc ccccactgat tcggccattt
     2341 ctgtcgtgct tttttggggt ttccctgtcc aactagggca tcaaaccccg tggtgtaggt
     2401 tgcaaaatga taattgtttg accagttctt ttgcatgaac ataaactggt taaataggtc
     2461 actctgaaag cataaaaata gcagtcccac cttttcatct tcccctggat atcgcgtcat
     2521 ttcttgtaaa tgagccaatt gattgttaaa gcgcgatcgc acgcataagg agtgatttcg
     2581 ggcattggga agttcgccat agctgatagc acgacgcacg atgcgatgtt ggcgttgttc
     2641 ctcaatggtt tgatgtcggt catttttgtc tccccgagga ttcactttac gaatgtgggc
     2701 atgaaatgga cattttaccc ccggcaaatc ctcatcatag ttgaaattat tagggactgg
     2761 atcaacattt tgttctgtag gaaactgggt gattggcgtt ccatctcgga aacgacctac
     2821 cactaatgct cccgctcttt cttcctcttt ttttgataac ttcaaggttt gaaaaagagc
     2881 tttttcggcg gccttaaatc cggatacatc ttgttcaagt ttgcggtaaa cacaatagct
     2941 accaaaacta tactctccct ctcccaaggg gtctttaact aacactaatt ctaagggggc
     3001 gctggggtcc catttgtcga aaccttgttg tttagccaga tctaggtcat ctttaaaaaa
     3061 tggtagtcct aagtatgtaa tgattcgtta taatcatgaa taaaatataa taaggcccct
     3121 atatgattgt ctaatttttt agaaaacgat aaggtttttc taaccagcct agaaattcgt
     3181 tgccttaagg tattattgaa ccgttcaata tggctagttt ttccgctatt tttgctgact
     3241 ggtttatatc gggtctttgg aaaaacacac tcgttggaaa aacacactcg tatgcttgcc
     3301 aaaaatctgt ataacaaaca gcacattccc gatacacagg cggtaaggat tcccataatt
     3361 ttccgctgat ttttgactcc tatctcctac ataaaagccg acaatttatc gggtttctaa
     3421 atctaaagcg agccacaccc actgttggtt ttgtttgttt tgaacataag accaaagttc
     3481 gtcacattca atgattagtt ttcctggggt tttagttgat acttcaagtt ccctggaaac
     3541 cttagcatac ttggcattga cgtatttctg aagccaagtt gctgacacct caaaaactct
     3601 gcatatacca gccaaaggca ttctttccag taagagcttg tcaatccatt ttttaatcga
     3661 gttggaaata tattttttac ggttattttg aacaaactgg cggccacagt ccttacattg
     3721 atgattttgc ttaccattat gaatatgacc attttttcgg atgttatggg agccacatct
     3781 aggacagact ggttgagagg cttcaaagtc attagacttt tggatgggtt gagaattcat
     3841 cgattttttc atatgttaat ttctctaaaa tttatggccc taatttaaca ttttctattc
     3901 cagaaaaata tttgaatttt aaatattttt tataagtcta gcttattaaa gtacaataat
     3961 tttggctttt attttttatc aacgaaggag atttctatta gtagtctagc cgcatcatta
     4021 catatttatg actacccaaa aagtttgagt gttcctctgg tatggtttcc catcattcaa
     4081 attttaatta atcgctactt tcctaaaaat aagcccattt atctggccct agatagaacc
     4141 tctaggaaac aaaacaacct tttcatgggt tccgtgattt atcaaaaacg agcttggcca
     4201 gtttattgga catttattga ccatacagga gccagcaatc tcgcccgtca aaaagccatt
     4261 cttactccga ttattcggtt attaaacggt tataaaatta tcgtcgttgg agatcgtgaa
     4321 tttcatagcg ttgagctggc tcattggctc cagtcaaaga aagtttattt tgccctccgt
     4381 caaaaatgca acacttacat taaacaaagt cggaaaaaag gcgaggattt tgagagctta
     4441 agtaatttag ggcttcaacc gggtatgaaa ctctatttgc cctcagttca atttactaaa
     4501 aagaaaggat ttggccgcta tgctttggcc gtttactgga aatgaaagta tcgctcaagg
     4561 aagtcgagtg aaccctggta tatcctgacc aatcttccgg acttaaaaag tgctttaaaa
     4621 gcttattcca tgcggatggg cattgaagcg atgttcaaag attgtaaaac tggaggatat
     4681 aatttagaag gaacaggagc caaccaagag cggttgactc gtctagttct tttaattgct
     4741 ttggcttata cggcctcatc tattcaaggc gtgccaatca agcaacaagg agtgcaatct
     4801 tgtgtcgctc gtttaaccga atctggacgc tctcaacgcc gtcatagtaa cttttggata
     4861 ggactttatg gactcagttg gattgattct ctggaaaaat tgcaggagtt gagtatcgag
     4921 tttatgaaac ttcaccccca taaacggcct ttttatcgaa ggggcctaag agctatgtcc
     4981 cttatccaat ctagtttcta gccggattgt caccccttca ggggatctac cactacccgc
     5041 gcactgcact cagaatgcga tcgaccattt cggcgcaagt ttgcctgcgg cgatcgcgat
     5101 cgccgttgta aggtaaagct tcagcactgg gattgattgc tcgcctcgct gtatttcgcc
     5161 atttcccgtt ccacgaagta gggctgtttc attctcccgg ccaaattagt ttttgggttg
     5221 ttccaaaact ttatccggca ggggatacag acgttttttc ctacttttta gcctattatt
     5281 agcaaataag gctgagaacc cttgggctgt aaggcttacg gtgtaaggaa aattttagaa
     5341 tgaaacagcc ctacgttcca cgaaggggat ttctttgccg agccagtagc aatctgaaca
     5401 atagccgcaa atattaaagg cagcattctc cattgagatt aagctgtcct caactcagtc
     5461 cccatttatc tgctagaaat gcatattcaa atgccacttc tttgagtttt tcgtagcgtc
     5521 cagatgcccc gcgatgtcct gccccttcat taattttgag cgaaacaata ttatcatcgg
     5581 ttttatgttc gcgcagctta gccgtccact tgacgggttg ccaatacggg acgttggcat
     5641 cgttcaaacc cgttgttatc aataaatggg gatactcctg ctgcttcacg ttatcgtaag
     5701 gcgagtaaga cttgatgtaa tcatagtaaa ttttattatt cggattgccc cattcctccc
     5761 aatcagctac tgacataggc aaggtcgtat ctaatataga tgtgagcgga tccacaaaag
     5821 gcgtttttgc aattgcaatt ttacacaaat ctgggcgcat attgagtacg gctccaatta
     5881 acaatccacc tgcactctca ccgaaaatcg ccaatttttc ctgagatgtc cacttatttt
     5941 ttatcaagta ttccgcacaa gcgataaagt cagtaaaggt attttttctg tgtaaaaatt
     6001 tcccatcttt atgccatttt tctcccattt caccaccacc gcgaacgtga gcgatcgcaa
     6061 aaacaactcc tcgattgaga agtgaaagtc gattggcaca aaaggaaata tactcgcaga
     6121 cgccataggc accataaccc acaagtaaaa gtggcgcttt gccattcttt tctattcctc
     6181 gtttgtaaac cagggagatg ggaattgctt cattgtccgg cgcgatcgcc caaattcgtt
     6241 cgctgacata ctcggttcga tcgtaaccat tgggaactgt tgtttgtttt ttgagagtca
     6301 actctctaaa gctcatgtta tactcaaaaa tggaatctgg agtaactaag gatttatact
     6361 caagtcgcaa attctccgta ttaaactctg gatttttatc ttctttaatt tcataaactg
     6421 actctggaaa ctcaatccag tgttcttctc ctgtagaaag ctggcaaatc cgaacttttt
     6481 tgactcctgc ttctctttca taaataacca atcgatctgc aaaagcgcta atttcttcga
     6541 gattcactcc ttctcgttcg ggaataaggg tctgccaatt ttcccgagat ggagagtcaa
     6601 ccaacgtttg catgagttta ccattaatgg cttcttcatt ggtcaatatg taaaatcgat
     6661 cgccgtggtg ttccagttta taccgaacct ctacagaacg aggatgaatg agtttaaatt
     6721 ttccattcat attatcgttt tctaaataat atatttctga tgtaagtaaa ctaattacct
     6781 ccattaaaat ataagattga ctgcgagttt tagaaacaaa tacattaaaa gtttcatcaa
     6841 attcctgata aatcaagatg cgatcgctga tggggtttcc tacagtgtaa cgaaagagtt
     6901 tatcagaacg gcttgtggca tccacctggg tataaaagca agtttgactg tcatttttcc
     6961 aaacaaaaga acacactcca ggaatgctct gggcgtagcg atcgccttcc actagattca
     7021 gaaaacaaag agtatagttt tcatcaccgt cggtatcgat agaataggct aaggtttgat
     7081 ggttaggact gacttcacac agatctaacc gaaagtagcg atgacctcga gccagttcgt
     7141 tacaatcaag aagtacctct tctcgattgt ctaagctgct ttgcttgcga caaaaaatag
     7201 gatagttttt tcccgcttca gtacgccaat agtaatagaa ctcaccttgg cggtaaggta
     7261 cggacaactc agcttcttca atgcgatcgc tcatttcatc atagaggcgt tcttgcagtc
     7321 ccttagtgtg ctgcatcatc aaatccgtat agtgattttc tgcttgcaga taagcgatga
     7381 gttgtggatc gttgcgatcg tgcatccaaa agtaattatc tattcgctca tcaccatgac
     7441 aagataggac gtgaagacat ttgggggcga tgggctggga tgttttttct gtagtcatta
     7501 acctaaactt ggcttaagcg gtcgatacat ttattgaacg atggtcgggt gggtagtgcg
     7561 tgcccacccg ccaaataagt aggtaggtac aaaaaatcga aactaagtaa agatatgtta
     7621 aggagagggg ccagacttaa acttaacccg tttggctgta tagtttccct ctacacttcg
     7681 ggcctctaca cctgccataa ccgcataagc taggtctagt tcatcttcaa acatacgtcc
     7741 ggctaattca tcacgtttca aatgctgcca ttctaattca atttcattca tttctgagca
     7801 gtatttaggg agtaaaaaga tgtacaatcc tttctcttcc catgaaggcc atttgttttg
     7861 aacctctaaa cttttatgaa tcggcccatt gtcttgcact attacccgaa ttcgtcctgt
     7921 tagggccaac tcctttgagg cttcctccgc ttctatttcc atcattttaa tataagattt
     7981 actggtgaaa cttccaatgg caaggccata ggtgaagcca atcttgggtt gcattattcc
     8041 taaaatgctc agtcttctcc cccgtatgcg cgtttgttct tgacattttt gttccttttt
     8101 tgggaaatag gtataaccga ctgaactcca taaacaaaag cccgactcat ctaaatactt
     8161 taggtcaatt tctctcgctg ctgcggcgaa ttccaacata tctagatcgg cttgttttat
     8221 cgaacgttct tctgggtctt gcttattttt atgactaatt cttgtccgtt tccaaattat
     8281 tccctttttt tttagcaccc gtctgagacg atcaggactt aggtacactt gccgttctgc
     8341 cgccagtttt ttagccagtt gtttactgtt ataggtgcgg ggttcctgcc taagacattc
     8401 ttctacataa gctatatcag catcttgcca ttttgctttg cttcctcgcc ccgctttgtc
     8461 ccacagtccc cctagtccct tcttctccca ccgatgcagt gtgtcccgga ctctagaaac
     8521 agaccagtta aagtgactag caatcttttc tacataccat ccatgagcat tcaaccggac
     8581 aatggaggct ctatctttta ccctttgagg tagagtggtt gccattctaa gttcaaacaa
     8641 ggttcgatct tcttctgggg taagaaagac tctcaggcga gcgcccataa ttttttcctc
     8701 taacgatggg acaggtcttt acttatcttt acatactttg gattttttgt acctacctac
     8761 ttagcttcgt cacgcagaga caaacccaat cctgcgatct atcggtggag gagagaatta
     8821 gggcggtcta tgggtcgcat gatgctggga gacgcgataa acccttctct ctatatgagc
     8881 agttttaaac cgctaccgga ctggaaatgt tgagtccgta aaaccgactg gggttatccc
     8941 aaaagatttt ttgcaaggtt ccatcgccca agcgatcgct ttgagcaatc aagtctgcga
     9001 tcgcctcggg tcgatgatcc atgtggggaa aatcagaact aaatagcaaa ttgtccgcac
     9061 cgatacagtc gatcgcctgc tccaaatacg gctcgctcgg ttccaccgaa ataaagcact
     9121 gacggcgaaa atactctgat ggcttcattt tcacattctc tttcacctcc cagccaaaca
     9181 gttcgtattc ttcatccagt cgccacaacc aatagggcaa ccaaccgcaa ccggattcca
     9241 aaaatgccac tcgcagtccc ggatgtcgtt ccaacacgcc gccttcaatc agcgccaaca
     9301 tcgccatcat ctgttccatc ggatgagaac aggcgtggag agcgaagcgg gtgttaaacc
     9361 gatccgcacc ggttgcaggc aagcgggaat gggtgccctc atggattccc actgcaattc
     9421 ctaactgttc gcaagctgcc caaaagggtt cgtaggccgg atctgagagc agtcgtccct
     9481 tgaccggatt gggacgcaaa aagaccgctt tccagccaaa ttcggcgatt cgctgcactt
     9541 ccgagaccat ctcctccggg tcgtgcagac ttatcgcccc cactccgcgc aggatgtgag
     9601 ggtcgtagct gcaaaagtct cgcaaccaat tgttataagc gcgggtgaag gcaccggcaa
     9661 gttgcggagc cattgtatcc actgcaaaca gccacagtcc catcgtcgga tacagaaaac
     9721 aaaactctac ccccatcgct ttcaccgcct gaacttgaga ggcgctgtcg tagcgagaga
     9781 tgccatagct gtggagatcg cgcaggatgg cactcagtcc agcttgctgc agttcttccg
     9841 agattttgaa atagattttc tccccgtcga tttccatttt aggagagggg gcacggtgtt
     9901 taaaggcggg ttcgagatac tcttgccaca tttcgatcgg ttccaatacg tgacaatcgg
     9961 catcgataat ctgatagcgg tcaaacatga gggttttcct ttagaaaaat gcgggcaacg
    10021 gatttaattg cgcttcggtg aggggttcgc tcacccatcc catttgatcg ggcacgtcat
    10081 acagccgacc cgaggcaaat ctcggccaaa agtgccgcaa tccggggacg acaactttga
    10141 ccaccgataa actgaggtcg ggtcgggttt ggttgacgac gagggtttcc atgcctttgg
    10201 cgcgaactcg ttcgacgcag gcgagaatat cggtatgcag atcgtcactc cagcagtggg
    10261 gatagtcggg gcgagttttt ggggcttggt tggagtcggg aagcagatag gggtggttgg
    10321 cgagggtggc ggtttcccac cagtcaatgc cttcgcgatc gcgatcgcgg taggcagtgg
    10381 tggcatcgag aatgccataa aaggcggcag gtaaggactg gttgagttcg gttaaggcgc
    10441 gaagcagagc gaggcggggg tcgaagtgag cgccgaatcc caagaggatg ttttccgggt
    10501 ggcgatcgcg gcgtggggag atggcggcga aggtgggaat ctgcaagtca gcagtcagat
    10561 ccagtaccca cagatcgcga ttgagagtgc ggtaatactc ttgcaggcga tcgaagtagg
    10621 gttcgtcaaa acttgacagt tctactgctg gtttgcgtaa gcgattgtac caccacaggg
    10681 cgatgctatc tcgttcgact agctctaaaa atccttggag gatagcttct tcgaggttgt
    10741 ttccggcagc gcatccattg ctatcggcgc gggtgaagta tgcttgatgc tgttgggaat
    10801 aaccggagta gcaataggca gtggggagat agcgaagttg gttgtgggtt aatgaccatg
    10861 caggagtcca ttcgatttcg gcattttcgt ccaagggttc gggaatccag tcaaaggtga
    10921 tgcgatcgcc attgagttgg gtgcggttct ggaattgccg agcgctaaat tgcatacagg
    10981 cgttggggtg aatgccattg tctaagttac tcaatgtgct acagatgcgc ggttcatccc
    11041 cttgaaaggt tccggcatag cgttcgatcg cttcacacaa ggcgctgact ttggcctgaa
    11101 tgtcttgtct gcctttgcca tacgcttcgg ttcgcaatcc ttcctggagg tggtgcaagt
    11161 ctgggaatgt tcccactgtg ggatactgag cgcgatagga atgggtcaat ccgtcaggag
    11221 tttcccaggt ggagatgcgc tgtagggtgg cgatcgcgcc gcagatggga ctgatgcgat
    11281 cggctaaggt attgtaggta tagtctgggg aatggctgcg atgtccgcca tcgcgggtaa
    11341 aggatttggg gcgcgattgc aggacgatcg gggcgaagtg agcgatcgtc aaggattcgg
    11401 ggttgccaca gcagggacat tggggacgtt gccagagttt gtgatagcgc tgttcccagg
    11461 tgagggtgtt gagggtgagg atttgacctt cgaggcggga gtgttgtgag gcgatcgccc
    11521 attttgcgat ttcggtggcg gcgatgctga gagcggtttg caccgtggcg ggaattgcag
    11581 caacggcggt ggggaggcaa ttttcggtct ggtggtgttc ttggagatag cgttcgaggg
    11641 gtcgatgtcc gcgcaggtaa tgggcgagac agtgccagca tccggttttg ccggggataa
    11701 aaatcgggcc gatccacagt tcgacgccta cgggtttgac taacatccaa gggcgatcgc
    11761 gctggatggc atcgcgattg caggcatcaa gaccggtttg caggtagtcg tcggtgagag
    11821 cgacggcaaa ggttccttcg tcactgcagt ttatccccaa ggaatcgagt tgggtggcaa
    11881 agggatgggg gtcgatgttg ccatagctga ggatggagag ggcgatttcc tggaggcggt
    11941 gggtggcgat cgccggttcg atgccctgga tttggtaaaa agcggcgcga tcctcgggaa
    12001 tcgagtcggt tgattcgata atgtacccca attctttcaa gcgatcgagc aaagtgtaga
    12061 tttcaaacac cgagagtcga tcctggaggc gatcgacgat ttctgtgacg gtatagttgc
    12121 cattgaggag gggagcgagt agcgtgtagg gggtgcctcg caataagaaa cgatcggttt
    12181 ccgacaataa aaatacccct tctaaaggca tcgtttcaca ccgaaactgc ggcttaaaca
    12241 tcggtttttt cagcatcgtt ctggaacgct tggtgttttt tcatctgttg tccatccagt
    12301 ttaaagagta gggtaggtca tgcccaccct acggtagatt gaattcggaa aaatcgcctt
    12361 taactgacat cttgtaccat tctcaacaag cctctgtcac ttgaggatcc ggcgtgggtt
    12421 taaacccacg cctcatagcg ttcagccggt ttccaaccgg ataaaaactt taccctacaa
    12481 gcatttcagt cggttttaac tgacatcttg caccattctc agtaagcctt tgtcacccga
    12541 cgatccgacg gggattttaa tcagagcctc atagctgaag tcggttgaaa acagactatg
    12601 agacttaccc cacaagctgt tcagtccact aagcgcggaa tgaacgctat tagccagggg
    12661 tttataaccc aagcgggggt gttgcaactg gtgcaagatc tgagttttaa ccgactttag
    12721 ctgttagacg gggattttaa tccccggcct tgctagtgca agatctcagc tttaacagac
    12781 tctcaaaacg ccgtacaatc catcttgatt ggcataggta taaagctgtt cttcgcttaa
    12841 attgccccgt tgcaaatgtt ctggtagcgg aggaagcgcc aagaatccct cttcagaatt
    12901 gggatcgttt acatattcca gaatcgtctg acaagcttgg cagagttgtt ccgaatcact
    12961 actttctccg ctggcgattt gctcgatcgt ctgtcttgga tctttattca gtcggcgcag
    13021 aaactctcgg tcttcctgac tccaggcatg ggcgaaaacg cgcgcccagg catttcgtaa
    13081 ttcttgtgga cattccactg gagagttaac tgcgggtttt ttttgcagag ttattgtcat
    13141 aattgacctt ttttcaattt ttagaatgtt cctgaagtat tgtggaaggt cttgtgcttt
    13201 tccacaagct gtacggaata gcatgggcta acaggtgaaa atttatttca ccttttggct
    13261 tttaaccctc gctttagctt tgccgcataa ttccgtagag ttcgctttga ttggcataga
    13321 gataaagctg ttcttcgctt aatcctttta gcccctctgg tagagtggga atggaaatgt
    13381 aaccgtactc gcagttatcg ttattgacat attcgagaat cgtggcgcag gggccttgga
    13441 tgctttctgg cgtacccgaa ttcataacat tggtaatggt gacttttgga tctttccgca
    13501 atccttggag aaattcccgg ttttcaggaa tccaagcata tccaaacagg cgagaccaag
    13561 catgggctag gtctggcgga tagggtgttt tatccatcgt ttacctacta ttacctacta
    13621 ttaattggaa gggttcgatc gcctcatctc gatcggttgc cacaactcta ccgggagcaa
    13681 tatttttctg tcaagattta tttacaaaaa ttcacaatgc caacaaatat tgacaattgg
    13741 ggcgatgcga cccagataca gcagatgtag ggtgggcaat gcagcgaacc cttctaaatt
    13801 tagaaatgtc agttcgccat tgcccaccct acggtatatt gagcagatgt agggtgggca
    13861 atgcagcgaa cccttctaaa tttagaaatg tcagtttgac attgcccagc ctacggtata
    13921 ttgagcagat gtaaggaact atccatgtca gtagatttaa cccaaaccca tatcgatccg
    13981 caggatccga tctatcaacc gttactagag gatttacagg cgaatatcct caaaagtcac
    14041 gatcgcgact actcggctca tctttttctg caattcaaac cgaacccaga tgcagtgcga
    14101 cagtggatcg cccggtttgc caaagaccgg atcgtttcag ccaaacaaca attaaaacga
    14161 tacaacgatc taaagacaac atcccgttct gaatcctcac aactttttgt taactttttg
    14221 ttaacctacc caggatatca atctttggga tttaacttga cagcaggcca acttcgagaa
    14281 tttcccagtc cagcttttaa agtggggttg gctcattttc agaccatttt ggacgatccc
    14341 ccagtggacg catgggaaga aggattccaa cgggaaattc atggggtggt gatgctggca
    14401 gacaataatt gggaaaacct gcaaacccaa gcgcaacaaa ttctgacaga actagaagaa
    14461 attgccgaaa ttgtcaatac cgaagtgggt cgggttttga gaaatagtaa aggagatgcg
    14521 atcgaacatt ttggctttcg cgatggcgtc agtcaaccgt tatttttcca acccgattta
    14581 gatgatgttg caaaacaaca aggcatcgat aaatgggatc cgagcgcacc gttagaatta
    14641 gtattagtca aagacccgtt aggtgaaggt gactatagct ttggcagcta ttgcgtttac
    14701 cgaaagctgg aacaagaggt cagcaatttt aaagcagcag aaaaagcctt agccaaagcg
    14761 ttgaaacttt caaaagaaga ggaagaaaga gcgggagcat tggtggtagg acggtttaga
    14821 gatggcacgc ccctgtccct agcaaacgcc gcacaaaatg ccgatccagt gccgaataat
    14881 tttaactacg atgacgattt gcgcggggtg aaatgtccgt ttcacgcaca cattcgcaaa
    14941 gcgaatccca ggggggataa aaacgatctc catcaaacct tagaggaaca acgccaacat
    15001 cgtatcgtgc gtcgggcgat cagttacggg gaattgccga tcgcccgaga taaatcccta
    15061 tcggtgcgat cgcgattcga gggtcaactc gctcatttaa aagacatgac tcgacatccg
    15121 atcgctgatg aaaaagtcgg attgctgttt ttatgctttc aaggtgatat tttcaaccaa
    15181 tttatgttca tgcaaaaaaa ctggtcaaac aatcagcact ttgtgagcta taccactgga
    15241 ttcgatgcac tcgtcggaca gggaaatccc aaaaatttac agcaaaagtg gcctcaatcc
    15301 tggggaaaag agggtgcgat cgactttgat ttttatcact ttgtgaagat gaagggagga
    15361 caatactttt ttgcccccag cattagtttt ttaaaaacca ttgattcgca aaagtgagtc
    15421 tgcaatccaa agcggcgatc ggttcgtcca gttttctcaa acaaagcctc gcaccctaga
    15481 agggtgggtc tataggaacg aagcccgcct gcgcgggcta tttttaacag cttttcctgt
    15541 tccctgttcc ttgttccctg ttccctgttc cctgttccct atttctgctt caacaccaca
    15601 atcgtaataa gctgtcgtgc atttagattt tatggtataa taaaaaacga aaacctataa
    15661 accaaaaaaa tgccagcacc taatcatctt agtgaaagcc aacaagagat acttttgaac
    15721 gaattacgtg aaaatgatag cccccttatt cgcgatagaa tcttaatact actcctaata
    15781 aatgatggta aaacctatga acaagtggcg aaatttttgc aaatctctta tccaactgta
    15841 gcatattggg ttaaacatgg cgatccagat aaattagaga gttttaaaga tggacgagcc
    15901 gaaggaaacc acaaaaaagc tacaaaagaa tatatagata tgctcttgga tattattgat
    15961 aaggaaccct cgaaattcgg ttatgaattt gggaggtgga catcagcaag attggcaaag
    16021 catttagaaa aagagacggg aattcacctg agtgaatcgc aagtgcggag aatattaaag
    16081 tcaaaaaagt atgtattcct ttgggcaaaa tatagtcttg aagaccgaca aaatccgctt
    16141 aaacgaaaag cgtttaaaaa cagattaaaa gaatacttaa aaattgctaa aagataccca
    16201 aagcgtttac aggtatggtt ttgggatgag acaggattca gtttacggat cgtaagaaga
    16261 aaacaatgga ctaaaagagg aaaacgtaaa accgtgagag gagatagaag gaaaggccga
    16321 ataaatgtaa tgggttgtct aagggcaact gacaaaaaaa gaattaactt ttttgtagaa
    16381 acaggttgtg gtgaatcatt ttatgaaagt ttaaagtctt tctacgcttt ggtcatacag
    16441 gaatgggtgg aacaaggtaa ttccgaagaa gattttttag aaaaggggcc taaaatagtt
    16501 attattttag ataacgcaag ctttcacaaa agaaaagata ttgccaagct tgccacagaa
    16561 gaaatgccta agatattttt agaatattta cccgaatata gtccggatta taatttaatt
    16621 gagttggttt ggcattcggc aaaagaatat atagccaaca agctatttga gtcaatttca
    16681 gaactagaat ctattttgca tagattgtta aatgaaggag aactcattat taactggggg
    16741 cgtaaaatca aaaataaagg caatcaggtt tattaaaact aaatgtacga cagcttatca
    16801 tcaaatactt tttgttcgcc aatatgccga cgcaggtcag cgatcgcagc ggcgcgcatt
    16861 tcctcagggg aaagttgcca gttttctccg ataatttggc agaggcgttc taagccgtat
    16921 tgttccccat cgagattttc tgcttcggta attccgtcgg tatagaggac gacggcatcc
    16981 cccggattta gttctatctg aatttgactg ataaaatcgg caatttccgt atccaatcca
    17041 atgagaaatc ctaaatccat cgtatcgatt tgctctacag tgccgccggt tcggaccact
    17101 agcacttctt catgttgacc gctaatggtc agggtgcgat cgctataatc caacaaggcc
    17161 aacgtcaaat ttttctcgct tcgcatccgc accacgttat cgaaaatcgt gcgattcacg
    17221 gtggttaaaa acttgacata atccgtctct tcattcacca ttaagggatt tccaaaaaat
    17281 aaaatcgtca tttctcaaac aggattatag atgatatcta caaaccattt gcctaagttg
    17341 gtctggttat ctggatcagc atttgtcagt ctatttagct ttttttccac cttttccatt
    17401 tcttttttcg tcaactttac tccagttgga taggtttgag taaccaactc aacttgggga
    17461 tttttcccct tccatgtcat agtttctgca aattttaaag ccgtcataac ttcttcaata
    17521 agactgccat tccaatgatg ttctaaggcg gaccaagttc gctctatggg attatattta
    17581 ctgtgataag gagggtagta tgctagacgc acgttgattt tatgacccca aacaaaatcc
    17641 acaattcgct tcataaattg agttcgccgg gaatgattct ccggcccgtt atcttgtttg
    17701 attaaaaggg ttttacagct tggaaatttg tgcttaactt ttgtccagaa agagtctaat
    17761 gtatctacaa taaaatcact cgtcactttg gattctgtaa aatatagaaa caaatccttc
    17821 cattctggta tcaaaattcc atagggagtt agtcggcttg atgggtgaaa atcatgatca
    17881 caagctactg ttggtactcg ggtttttccc ctcgtgaaaa cgggccaatg tcaacggcag
    17941 ccttggcatc cattgagatt tccaaggtgg tagggtcttg ggcagcctca ccagttactc
    18001 tactcatttg ttcaaaaatt tcatcagtct cgggaatttt tttttgaggt ttaaacttgg
    18061 tgactttctg aggataatac cctaactcat tcaattttat ccggattgtt tctgtgcaag
    18121 caaggcaatt cttcatctct ataattcttc tgctcaatta aagcctttct aacgcacgag
    18181 gcactcaacc ttctatataa tcggttggtt tgaaaggtcg gatccgtctg gctctgacta
    18241 tctactatgg atttaatatc gaataataaa ttagggagat gtatttcagt ttttttacgc
    18301 cctctagctt gataattatt tacacaggtt attccggtct ctagctcccg aacaccttga
    18361 cgaattatgt ctctattcca tcccaactct cgggcggctc ggctctgtcc tgcgtacccc
    18421 atctcaataa ctgtctgggc cataaagcgg cggcgttgtg ccccttttaa ttgagaagct
    18481 gtttctttca ataagttttt cagcgaatct gttaattcca tctgggttat aatcggtctc
    18541 aatggcttga attctttatt ttaccagctt tttgccagat ttattttttg ggactcccta
    18601 acataatggc cggatgagaa tctacattag cctcgtcatt aatggcttca taataccata
    18661 gtaaaacttt accgtccact gcaatagttt cgctctctat tgggtcaatc ccaaaaaaac
    18721 gagataaaca ggctgagtag cgttgctgct caattcgtaa taacgttcgt cgaatcgtac
    18781 tgtaagaggg taagcggttt ttttcaggtt taaacaattc caacagttca tcatggtagg
    18841 cttttaacca atctccaatc gctataaacc ctcgatttcc agcagcaaca ccgagggtaa
    18901 ataaggctag acagaggctt tgtttatgcc gcgtgcctgc ttgacgtcgg caatcctcta
    18961 gatcggcaaa tgcttgaaca atggctatct gagacatttt gaactgaccc gtcggtgaga
    19021 ttactctgtt attctatcac gtcttacctt agaatgaaat agccctgcat taaatgcagc
    19081 aatggacgat ggatttatcc tcccattgag tgaaaattat acattaattg aaactgatgt
    19141 agaagaggta aaagaacact taaacattga ctataaattt gctcacgatc gcatccaaca
    19201 agcagcctac tccttaattc cggaaaccga aaaatcctcc gttcattggc aaattggaca
    19261 attgctcttg caaaatactc cggtaaacga acaggaagtc aaaatatttg ccctagggcg
    19321 tcggttcagt acccgggctt gacaaaacgg ctggactatg cataactgaa atggacgacc
    19381 cgattaaatt caagccctca ttacggtata aagtctatgc gtcctccttt gtggcacccg
    19441 ccagtagagc tatcagattc agaacaggta attattaatc gcatcaaaaa agccaagctt
    19501 tttacttttc ttcgcctgaa ccgtttgttc atattcgatg atgagtttca agaagaacta
    19561 aacaccattt ttaaagacag cacaatgggc aactgtccca tcgcaccagc ccaattggcc
    19621 ttagccacta ttctccaagc ttatctgggt atttctgacg aagaagtgat tgaagagcta
    19681 gtcatggatc tccggtggca attggttttc gattgtctac attgtgaaaa acccccattt
    19741 agtaaagcca ctttaataag attcagaagc gccttaatta aaaaggcttt gaccaacgtt
    19801 taattgaccg tactgtagaa attgccaagc tcaaaggagg ttttggttcg gctaagttaa
    19861 gagctgcatt agattcctct cctttatggg gtgccggtaa agttgaagat acctataatc
    19921 tcttgggtca tgctctgcgt aaggcgttga gtataatagc tgtacagcag gggtgggggc
    19981 tggcagaaat tgccaatgaa gccggagcgg attttgtcaa tagttctagc ttaaaagccg
    20041 cattagattt aaactgggat gacccaggcg aaagccaaca ggcattatca actatactaa
    20101 acagcctgaa ttctgtagaa gaatggatgc aacagcagcc taatcctgat gaaatagaag
    20161 aggcgcaagc tcctctccag gttgcccgat tgattgaatc ccaaaatgtg acagcagact
    20221 caatgggagt gccgaagctg gccaaagggg tggctaagga ccgacgcatt tctattgaag
    20281 atccagatat gcggcatgga cgaaaaagcc gctctcaaaa aataaatggt tataaacgcc
    20341 atattcttaa agatttagat ataggagtga ttcgagcggt ggctgtaacc cgagctaata
    20401 caccagaatc cgctgccact gttgacttag aacttgactt aaaaagacaa caggttcagt
    20461 taaatgaact ccatatcgac cgagcttatt tgtcgagtca ttgggtaaaa gaacgctctg
    20521 aacaattaca aatattttgt aaggcatggc cagtaagaaa ctcaggacga tttgataaaa
    20581 acgcttttgt ttttgactgg gaaaaccagg taattagttg tccaaatcaa gttattatgc
    20641 cgtttgaacc cggtaaggtc gttcattttc caaaaccgga ctgtgcagtt tgtcccctga
    20701 gagaacgctg tactacgagt aagaatggcc gcagcatatc tatccatccc gatgaaggat
    20761 tgatgcagga attgcgtcag cgtcaatcta catcaagcgg tcgcgcacaa ctgagggaga
    20821 gaacctctgt agaacattct cttgctcatg tcggacagtg gcaggacaaa cgcgcccgtt
    20881 atattggaca gcgcaaaaac ctcttcgacc tcagacgagt ggctgttgtc cataatcttc
    20941 atgtcattgc tcgaatgaat gaggttttac caatacaaca ggccgcactg tagttgaatc
    21001 aagcaggtaa atacacattt tctgagtttt gtcaagattt tttactgaac cgacgcccta
    21061 gtcaaccacc taaaccaagg tcgagatcgc attgctgaac ccgcccaagc cgaagaactg
    21121 gcccacctca acctcaaagc cggtaaaaaa gccaaagcct ctgctgccta tcaacccgcc
    21181 ttcacctact tggtcctggg cttgaatttg ttaaccacag agtgttggaa atctcaatat
    21241 gaattaacct tagccctcta tcaagaagcc acagaagccg cttatctcag cgacgatttt
    21301 cagcggatgg aggaattcgc aaatcaggta aaaattcatg ctcaaagcgt cattgataaa
    21361 gtccaagttt atcgagcatt agttctcggc tatgctaacc agcaactcct ccccgaagcg
    21421 atcagaaatg ggttagaaat tttacaagac ttagaaattg tcctgccgga acagcccact
    21481 ccagcagata tcggccaaga gttaggagta acccaaaccg cctgggaagg acaggaaatt
    21541 gaggcgttaa tcgacagacc ggagatgaca gacccctcca agcaagctgc aatggatttg
    21601 ctatttgatg tcattcatcc cgcttatgat agcaaccctg ccttgttcac cctttgtgcc
    21661 ttaaaaatgg tgcaactttc tctccaatat gggaatacac ctctctcagc ccagggatat
    21721 gcttcttacg gaatcgtgtt gtgcggggtc gttttcgata ttgattctgg gtatcaattt
    21781 gctaaacttg ccttaaaact gctcgatcgc tttcaggtca agaaaatcaa atcggcagtg
    21841 ttctttttgg ttttttattt ttccatccat tggaaagaac atctcaaaga aacattacct
    21901 ccttttttgg aaggctatca agctggactg gaaaacggag atttgctatt tgcggctttt
    21961 aacgcttacg gctattcttc ctattactac tggatcggaa aagaactgcc cttcgtcgaa
    22021 cgggagatgg cgaaatatag cgaagcgatc gcccgcatca atcagaacct cattctcagc
    22081 tatcaaaacc gctattggca agtcatatta aactggatgg gtcagtctga aaatccctgt
    22141 ctgttagtcg gggaagccta taacgaaacg gccttattac ccatgatgat agaaacgtca
    22201 gaccgatacg gaatcggtga cttacatctg cataaattca tcctttctta ttcctt
//
