LOCUS       NZ_JH941049            22712 bp    DNA     linear   CON 20-MAR-2024
DEFINITION  Streptomyces sp. SS scaffold13, whole genome shotgun sequence.
ACCESSION   NZ_JH941049
VERSION     NZ_JH941049.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. SS
  ORGANISM  Streptomyces sp. SS
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 191758)
  AUTHORS   Wang,L., Xie,Y., Li,Q., He,N., Yao,E., Xu,H., Yu,Y., Chen,R. and
            Hong,B.
  TITLE     Draft genome sequence of Streptomyces sp. strain SS, which produces
            a series of uridyl peptide antibiotic sansanmycins
  JOURNAL   J Bacteriol 194 (24), 6988-6989 (2012)
   PUBMED   23209237
REFERENCE   2  (bases 1 to 191758)
  AUTHORS   Wang,L., Xie,Y., Li,Q., He,N., Yao,E., Xu,H., Chen,R. and Hong,B.
  TITLE     Draft Genome Sequence of Streptomyces sp. SS, which produces uridyl
            peptide antibiotics sansanmycins
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 191758)
  AUTHORS   Wang,L., Xie,Y., Li,Q., He,N., Yao,E., Xu,H., Chen,R. and Hong,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2012) Key Laboratory of Biotechnology of
            Antibiotics of Ministry of Health, Institute of Medicinal
            Biotechnology, Chinese Academy of Medical Sciences and Peking Union
            Medical College, No. 1 Tiantan Xili, Beijing 100050, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Sep-6-2010
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000302615.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 03:40:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,332
            CDSs (total)                      :: 7,257
            Genes (coding)                    :: 6,818
            CDSs (with protein)               :: 6,818
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 1 (16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 440
            CDSs (without protein)            :: 439
            Pseudo Genes (ambiguous residues) :: 0 of 440
            Pseudo Genes (frameshifted)       :: 293 of 440
            Pseudo Genes (incomplete)         :: 173 of 440
            Pseudo Genes (internal stop)      :: 7 of 440
            Pseudo Genes (multiple problems)  :: 33 of 440
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:58:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 128204
            Orig. end                         :: 150916
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JH941049.1.
            Bacteria and source DNA available from: Institute of Medicinal
            Biotechnology, Chinese Academy of Medical Sciences and Peking Union
            Medical College, No. 1 Tiantan Xili, Beijing 100050, China.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22712
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22712
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22712
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12712](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12712
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            527..1384
                     /locus_tag="Y19_RS0134655"
     CDS             527..1384
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056023.1"
                     /locus_tag="Y19_RS0134655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_017242091.1"
                     /transl_table=11
                     /translation="MDDLAGFLRTRRSRVDPAVAGIPTGSRRRVAGLRREEVAHLSGVS
                     VDYYVRLEQGRATQPSEQVLDALARVLGLDDTERGHLYRLARQHRRRAKAPAGRVRPEL
                     RRVLDLVTDAPALIMDHRLGVLAGNRLAALLYGRPLSGLNTARHIFLEEAERGLYADWE
                     KCTLDVVGHLRLAAGKYPDDPRLASLIGELAMGSERFRRLWARADVRARTHGRKAYRHP
                     LVGLLELHQENFALPDGSGMELLVLSAPPAGPTEDGLRLLARLDADSDASPPASHVTRI
                     GETT"
     gene            complement(1455..1901)
                     /locus_tag="Y19_RS0134660"
     CDS             complement(1455..1901)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="Y19_RS0134660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_017242092.1"
                     /transl_table=11
                     /translation="MNKFKAFALTVGAATAAHADGNVTWRSAYTDLCLASIDNNWGYPS
                     NVAMRGCGNAGTTWHEQDLGDGTWLMRTTSDQDFCLTAYSDHDVYMEHCSGNVWQRWSE
                     EWDGDRGVWRLKHAATGWYITDYDRGLQIGVDPLNYWDSRQWWR"
     gene            2060..2698
                     /locus_tag="Y19_RS0134665"
     CDS             2060..2698
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007383465.1"
                     /locus_tag="Y19_RS0134665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_128643963.1"
                     /transl_table=11
                     /translation="MQRRVQLKVCGLGTAADVDVAVAAGADAVGLVISRTSVRGLERDR
                     AARLAVHVPQGVLSVLVVNDTPAADAARIAGELGFGALQLHGTAYQEDDFAVAAGIFPR
                     LWRATSLSDRPDTRVGAYGEEVLLLDSPQAGSGEPWDLSLLESGRPRGTWLLAGGLTPE
                     NVAEAIGRACPWGVDVSSGVESSRGVKDHQRIRAFVAAAKEAAVEQAAS"
     gene            complement(2756..3964)
                     /gene="fabV"
                     /locus_tag="Y19_RS0134670"
     CDS             complement(2756..3964)
                     /codon_start=1
                     /gene="fabV"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036930.1"
                     /locus_tag="Y19_RS0134670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-[acyl-carrier-protein] reductase FabV"
                     /protein_id="WP_017242094.1"
                     /transl_table=11
                     /translation="MSERVIAPKSRGFLFLDSHPGGCRQVVDDMWQAVPAPVAPGGEGP
                     VALVIGSSAGYGLAATIAGLARIGIRGIGVCFEKAPARRTGTAGWYRTAATARLARQHG
                     RDMVFLNGDAFGDAMKEEVADLLAERFGGRLDYLIYSVAAPRRTDPDTGEVYASVLKPV
                     GSPYTTKTLVFDQDGAPEVKEVTTGPAEGDDIEQTVAVMGGTDWERWVTFLADRSLLAD
                     GFTTAALSYIGSPLTAAIYRQGTIGAAKSHLEATARTLDERLGKTLGGRAVTSVNAAAV
                     TQSSTAIPGIALYVGLLRGVLGDSMIAPIGQLVQLWDQLTGARPLDLDDEGRVRLDTWE
                     LDPTVQNAVAERWSIATSDSITGLADLDWFSDEVRRLYGFSVPGIDYTAAVESDVAWPA
                     PTA"
     misc_feature    complement(3954..3969)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.6"
                     /tool="antismash"
     misc_feature    complement(3979..3997)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.49"
                     /tool="antismash"
     misc_feature    complement(4202..4213)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     misc_feature    4231..4246
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            4340..6058
                     /locus_tag="Y19_RS0134675"
     CDS             4340..6058
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="Y19_RS0134675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_128643965.1"
                     /transl_table=11
                     /translation="MQQTMGFEQLTDAELIRAAQWGAPWVRQHLVAVYQPLVHALAARA
                     LDGRADADEVVRSVVQDTLGRAEFTLGTLPQVEAVRPWFVSVAVASTLSHAAGVRAQPA
                     VRAGSGGDPAGVLLWLDVEDALMTALWSLEQDGWLSRYETAAALSWSAHDTATRMEAVG
                     VRMDRARSVTVALAREPRCPALARQVSAWDGRPGAAWREELAGHTVQCAHCATGIVAAG
                     PSRATATAAVSAVGAGGGMPAAPTDHAAFDAFDTFDNLDASGAFDATGTYLLRPHPADP
                     SAPAGHVATAAAVGSRSSRAARRRRRQADERTRRRATVAAGIAVAAVTAGAFSLQSRDG
                     EDRLEANRAAAPGLDLPLGNEPGTLTASPSTAAASPSASASATAKPSGAPTKATATPTK
                     SPRPTTATPAPKRPTTPAATTAAPTRSATPTGGTDTGPGGGSQQDTGQKSTADQVIALV
                     NAERAKAGCGPLSANAALTRAAQGHSDDMAARDFFDHTNPDGDGPGQRVTAAGYPWSTY
                     GENIAMGQKTPEQVMEAWMNSPGHRANILNCDFKEIGIGIHSSGGPYWTQVFGAR"
     gene            complement(6129..6425)
                     /locus_tag="Y19_RS0134680"
     CDS             complement(6129..6425)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124381.1"
                     /locus_tag="Y19_RS0134680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_026058747.1"
                     /transl_table=11
                     /translation="MNGDEQLLRGRVYGHDHDDPDPGPLPGQSYAVLVGGPLDGLLLDV
                     TGWRPEEVDDGAALATELGQWPGGRSLYDPRPGEARRPGPGIVCRFHHSGDTP"
     gene            6744..7478
                     /locus_tag="Y19_RS0134685"
     CDS             6744..7478
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038112.1"
                     /locus_tag="Y19_RS0134685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017242096.1"
                     /transl_table=11
                     /translation="MATKLNQIIAVEKGVKSRAHQDLTAAHHGLQKPALLAGISRTYQP
                     KDEEGEQLPPESTLVQVKAEDVLRDTARALTRLFDVTATKDWANCDARADVTVDGRVLV
                     AQVPVAYLLFLEKQLTDISTFVRKLPVLDAAESWTQDPSTDAWKTEVVRTVRTKKVPRN
                     HVKAEATDKHPAQVEVYYEDVPVGYWTTVKFSGALPARRVNELLTRVEKLQQAVKFARE
                     EANSAEVTDQRVGDAVFGYLFG"
     misc_feature    complement(6745..6759)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     tRNA            join(7514..7545,7549..7601)
                     /anticodon=(pos:135746..135748,aa:Leu,seq:aag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="Y19_RS44465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Leu"
                     /pseudo=""
     gene            7514..7601
                     /locus_tag="Y19_RS44465"
                     /pseudo=""
     gene            complement(7920..8696)
                     /locus_tag="Y19_RS0134690"
     CDS             complement(7920..8696)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (13-185). E-value: 1.1e-15.
                     Score: 50.0. Matches aSDomain:
                     nrpspksdomains_Y19_RS0134690_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020555524.1"
                     /locus_tag="Y19_RS0134690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_017242097.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-38, bitscore:
                     126.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTYPSSHPLAGRVAVVTGASSGIGEATAEHLAELGAKVVVLARR
                     ADRLHGLVARIEKNGGEALALALDVTDASAVQAAADRVASEYGGADLLFNNAGVMLPAP
                     VEELATDQWQHQIDLNITGLMNVIGAFTPQLVTAAGERGVADLINTSSIAARNIFPNFA
                     VYSATKAYVTHLSRHLRAELGAKNVRVSAIEPGIVATELQSHVTDEGALAWLEDAKEAM
                     EWLTPADVAHTVGFAATLPPRANLQQITIMPTAQPS"
     aSDomain        complement(8142..8657)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Y19_RS0134690_PKS_KR.1"
                     /evalue="1.10E-15"
                     /label="Y19_RS0134690_PKS_KR.1"
                     /locus_tag="Y19_RS0134690"
                     /protein_end="185"
                     /protein_start="13"
                     /score="50.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGASSGIGEATAEHLAELGAKVVVLARRADRLHGLVARIEK
                     NGGEALALALDVTDASAVQAAADRVASEYGGADLLFNNAGVMLPAPVEELATDQWQHQI
                     DLNITGLMNVIGAFTPQLVTAAGERGVADLINTSSIAARNIFPNFAVYSATKAYVTHLS
                     RHLRAELGA"
     CDS_motif       complement(8562..8651)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Y19_RS0134690_0001"
                     /evalue="1.60E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="Y19_RS0134690"
                     /protein_end="45"
                     /protein_start="15"
                     /score="24.0"
                     /tool="antismash"
                     /translation="VVTGASSGIGEATAEHLAELGAKVVVLARR"
     gene            8919..9794
                     /locus_tag="Y19_RS0134695"
     CDS             8919..9794
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006137725.1"
                     /locus_tag="Y19_RS0134695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_017242098.1"
                     /transl_table=11
                     /translation="MDERGRELADFLRTRRARVTADQAGLPDDGRVRRVPGLRRDEVAR
                     LAGVSTEYYTRLEQGRAQNPSPEVVQALADTLRLDPSEREHLTDLFARPTPARRAPVGP
                     QRVRPGLHLMLGTLGHVPAFVLGRRTDVLASNRLAREVLTDFDALPAPRRNLALYYLLD
                     PEARVRVGDWERIAAETVAILRLEAGRATHDRRLADLVGELTLKSPEFTSWWNDHRVLR
                     RTHGAKHYRHPLVGDLHFSYESFQVPGDTDQTLCVYNVEPGSDTAEALRLLTSWTAPQT
                     VRSRASEPGA"
     gene            10001..12712
                     /gene="lanL"
                     /locus_tag="Y19_RS0134700"
     CDS             10001..12712
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955211.1"
                     /locus_tag="Y19_RS0134700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_017242099.1"
                     /sec_met_domain="Pkinase (E-value: 5.2e-18, bitscore: 58.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.3e-42, bitscore:
                     137.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASHITEVDLEGVLRRALRATGTGARWAAEADEMWCRVATRAGVR
                     REQGWKLHVSATVASAPEVLDRALGVLLRGESGFKFARSLEQVGVLNSRATPRGSSGKF
                     ITVYPCSDAEAAALAERLHAATAGMAGPRILSDQPYAVRSLVHYRYGAFVGRRRLSDDG
                     LLVWFIEDPDGNPVEDKRTGRYEPPPWAVSPFPAVTPAPSRTGEGDEGGVVLGGRFAVR
                     EAIRHTNKGGVYRGSDVRTGAPVVIKEARPHVEADASGCDVRDWLRAEARMLDRLKGQG
                     LAPEPLALFEHGGHLFLAQDEVPGVTLRTWVAEHFRDAGGARYRADALLQVARLVDLVE
                     AAHARGCVLRDFTPANVMVRPDGELRLIDLELAVHTDEAALPTRVGTPGFSAPERLADA
                     PVRPAADYYSLGATACFVLAGKVPNLLPEEPAGPAAEQRLAAWLTACAGPLDLPDGVVE
                     MVLGLMRDDPAERWDPVRAREALRRSTRTATGSVAVGPAAVASRAVEPDVGSVVAGLVE
                     HLIGSMTPDDDRRLWPVSTTAGESDPCTVQQGAAGVLAVLTRYFELTGDPRLPEVLSTA
                     GRWIAGRADARSPRPGLHFGGRGTAWALYDAGRAVDDRALTDRALALARAPQQATPHHD
                     ITHGSAGSGLAALHLWQRTGDARWAEFAVEAADRLTAAVRRGPDGVGWAVPAEAVDPDG
                     GSSGDASAGGGKRYLGFAHGTAGIGCFLLAAAAVSRRPAHRELAVRVGEGLVASAVLSG
                     EAAQWPAQAGDLPTAPYWCHGSAGIGGFLVRLWQATGDDRFGDLARRSTRAVAERASRA
                     PLTQCHGLAGNGDFLLDMADATGDPAYRSMAGELARLIVCEKTDRRGQVVFPNEYGDVS
                     TSWSDGSAGILGFLLRMRYAGTPRHWTVQPPA"
     gene            12943..13098
                     /locus_tag="Y19_RS44470"
     CDS             12943..13098
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031827.1"
                     /locus_tag="Y19_RS44470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VenA family class IV lanthipeptide"
                     /protein_id="WP_017242101.1"
                     /transl_table=11
                     /translation="MENHDIDLLARLHALPETDPVGVDGAPFAATCECIGLLTLLNTVC
                     IGISCA"
     misc_feature    complement(13282..13295)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.52"
                     /tool="antismash"
     gene            13379..14494
                     /locus_tag="Y19_RS0134715"
     CDS             13379..14494
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552846.1"
                     /locus_tag="Y19_RS0134715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_017242102.1"
                     /transl_table=11
                     /translation="MQPHVGDDDHPPTALLTAAPAGPRGARHHPEPVSAITARALGKSY
                     PGPEDAVTHAVSGLDLDVAAGETFAFLGPNGAGKSTTIALLCALARPTAGRATVAGADV
                     LTQPHLVRRRVGMLFQHSAVDGDLTAEQNLYIHARLYGMPRGQVRRRTAEVLETAGLSD
                     RRRSPVRTLSGGMRRRLEIARQLLHAPGVLFLDEPTTGLDPHARAQVWHHLRTLRERHG
                     STLFVTTHYLEEAENCDRIAIIDRGRLVAQGTPVALKAAIGDDRVVLRTGDDTGAHRIV
                     RTLAPPGSALGADAAGVSLRVPDGSSWIPRLCAALTAQGIAVHSASATPPTLDDVFFHH
                     TGRSLDPAQPGGPAPLRPSSPRATTESGGSR"
     gene            14491..15405
                     /locus_tag="Y19_RS0134720"
     CDS             14491..15405
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955215.1"
                     /locus_tag="Y19_RS0134720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_017242103.1"
                     /transl_table=11
                     /translation="MTALGRKAPDGPAAGPSGTSRAAEADGTGVAAGHGRFTRPRHELR
                     AIHALVHRDLLRLGGQRTHTALMLLHPALYLLILGGGLASLIPRSQLGVGYQAYLFPGM
                     LMMTVQTPAIMVGVRLITDRQSGYLRELLMAPVHRSTLLLGNCAGGTLVATAQGAVLLA
                     LAGVAGLPYDPVLLVLLLGCMVLASFTVTALALALAVSLHRAETFHTLLGVVMMPLLFL
                     SGGFFPLTVLPRWVHVLADANPLAYAVDLLRRCISLRVPDHAATAGLDWAGRRPPLLLE
                     AGLLLACGALALLWAARRFNRPE"
     gene            complement(15389..15958)
                     /locus_tag="Y19_RS0134725"
     CDS             complement(15389..15958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040384.1"
                     /locus_tag="Y19_RS0134725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Clp protease N-terminal domain-containing
                     protein"
                     /protein_id="WP_026058748.1"
                     /transl_table=11
                     /translation="MFERFTQAARAVVKGAVEHAERDGTKTVTKEHLLLALLDRQDTRA
                     AAALRTLCPPDRRPSLTAALAAARRRAGLSRADTQALADLGIDVGAIVDRVEEAHGAGA
                     LAGDRKDPGWWSGRQTFSREAKTVLEKSLRVALARKDREIGDEHILLALTMTGGVVAEA
                     LADHGVTYTAVDTLVTGPKAQVIPGG"
     gene            complement(15958..16167)
                     /locus_tag="Y19_RS0134730"
     CDS             complement(15958..16167)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447814.1"
                     /locus_tag="Y19_RS0134730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_026058749.1"
                     /transl_table=11
                     /translation="MTDATDLAARAGDRDPRVGLRAVSALRRLLEQLEAVQVRSARNQG
                     WSWQEIAAELGVSRQAVHKKYGRQ"
     misc_feature    16309..16324
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.98"
                     /tool="antismash"
     misc_feature    complement(16325..16339)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.52"
                     /tool="antismash"
     gene            16372..17901
                     /locus_tag="Y19_RS0134735"
     CDS             16372..17901
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960261.1"
                     /locus_tag="Y19_RS0134735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_026058750.1"
                     /transl_table=11
                     /translation="MSQSHEPWYRHRPPPWPVPDNPYAPEGYGPPPPGRRRRWPVLAAG
                     LVLLLLVGAGGYVLTQHGGAGRTPPVAQGTTGPPKTTGTPPPTTKPTAAPSHIPTTAEI
                     ARQHRSGEASAWIVDDRTDLPRRDIPLQDLWIVGDTAVQAVYKRVVAHRLGDGAELWSV
                     ALPTPVCETPVHPTPDGKVVVVLKNVEAWTGARCNQLWMIDLRTGKAGWHKQLTETGSG
                     DDTIMVDSAVSGGTFAIVQSMKATAYRVVDGRKLYDIPLEDPGKCYPGRVAGGSRLLVV
                     SDCAITALEKSYSQLREIDPATGKVRWRYRTEPGHVIGQVLAVDPAVITTVRKETSGAD
                     WRVVALGPDGRVRGTVDPRAKGFTHCGDSVDTSGDAQACREAVVGAGLVLLGGTDRVGA
                     YDLATGKPVWGVKSEGTSYGYFPLRVGPGRTGLVYRVAALGEPGRVFRVGPGGVDTIKD
                     VLKLPAATSRLEFGMGVVGRNAYVGDRLVLAPRGMSGDDAQHEPRMLSFAP"
     gene            complement(17911..18990)
                     /locus_tag="Y19_RS0134740"
     CDS             complement(17911..18990)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045218.1"
                     /locus_tag="Y19_RS0134740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_017242107.1"
                     /transl_table=11
                     /translation="MRRRPGLSARLKLTLSYAGFLALAGALLLVVVWAFLLRYVPDNSQ
                     GLLGVSPNRYLLVRTFAPAAAAAMAFLLLFGLVGGWILAGRMLAPLTRITDAARSAASG
                     SLSHRIRMEGRQDEFRELADAFDTMLERLESHVAEQQRFAANASHELRTPLAISRTLLD
                     VARKDPTRDRDELIARLQAVNTRAIDLTEALLLLGRSDRGHFTREGVDLSLVAEEAAES
                     LLPLAERRGITLDVTGGPTWTTGSAELLLRMATNLVQNAVVHNLPAGGTVTVRTDAEGT
                     TSVLRVENTGRRLPPELVPTLTEPFQRGAERARTEEHPGVGLGLALVHSVVRAHDGTLD
                     LAARPAGGLLVTVRLPGAP"
     gene            complement(18983..19777)
                     /locus_tag="Y19_RS0134745"
     CDS             complement(18983..19777)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610517.1"
                     /locus_tag="Y19_RS0134745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_017242108.1"
                     /transl_table=11
                     /translation="MRVLIVEDEPYLAEAVRDGLRLEAIAADVAGDGDTALELLSVNSY
                     DLAVLDRDIPGPSGDEVARRIVASGSGIPILMLTAADRIDDKASGFELGADDYLTKPFD
                     LRELVLRLRALDRRRAYARPPVRKIAGLRLDPFRREVFRDGRYVALTRKQFAVLDVLVA
                     AEGGVVSAEELLERAWDENADPLTNAVRITVSALRKRLGEPWIIATVPGVGYRIDTRTN
                     PAANTPADTPAEPRTGSADPDGGTTTDPGGGDATAPGGSGHA"
     misc_feature    19729..19743
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(19858..20565)
                     /locus_tag="Y19_RS0134750"
     CDS             complement(19858..20565)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014182086.1"
                     /locus_tag="Y19_RS0134750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VanZ family protein"
                     /protein_id="WP_037968889.1"
                     /transl_table=11
                     /translation="MNHNASPSARPGRTGRTVLVGLAVLALAGGLFVVRGPLMMSAPRC
                     MAGRWHGCYDTFNGVVLMTLVALPLALLVVWVLARRRRSAGDASAWRTSLAEVGMVHGT
                     LPFLWLTMMPGGGAGVVPARVSLVPLRDLVTMGPLGIGGNLLVFAALGFFAPMRFAALA
                     SVPRILALGAGCSVLVETAQYVLRLDRVSSVDDVLVNAAGAVLAALASRRWWRTPEATR
                     SEEPQRPVPAAAG"
     gene            complement(20661..21110)
                     /locus_tag="Y19_RS0134755"
     CDS             complement(20661..21110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034644.1"
                     /locus_tag="Y19_RS0134755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6223 family protein"
                     /protein_id="WP_017242110.1"
                     /transl_table=11
                     /translation="MSTRPSARRPLATVTAACAAAVLGSLAFAAPAAAHVASAQPLAAS
                     VYDFGPGRAGSSAAAFLALAGVVVGWLALARPTGRFGVASGPLGARIALVAGLVGTAVG
                     VLVAATADGGLGTGNGLGGAFVAILVGVASTVLGWRATVRVRRGA"
     gene            21325..22452
                     /locus_tag="Y19_RS0134760"
     CDS             21325..22452
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005320942.1"
                     /locus_tag="Y19_RS0134760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_026058751.1"
                     /transl_table=11
                     /translation="MSASTARMWARFGDGVIAVGVAAALVVTGLSQRVPVSGQAVVGYA
                     LLALGGLALAARGRAPVAVLVVTGVCAAGYQAAGFDVAAVAYLFAVYGAVRAGHRTVAV
                     VASVVVLALLPLAALASGSHDTGEAFAQARGALEIAWLVAAGAAGEALRQAEQRAEEAE
                     RTREETARRRADEERLRIARELHDSLTHQISVIKVQAEVAVHVARKRGEDVPASLLAIQ
                     EAGREASRELRATLEALRDDDTTPPRGLDDVPELVRRARTFGLDATLTVEGTHRDVSAA
                     VDRTVYRIVQESLTNVARHAGATTASVRIDCRPDTLEIAVVDDGRATTGAAPTPGLGLV
                     GMRERVTALGGRLRAAPRDGGGFAVRAELPVDRAS"
ORIGIN
        1 cgtatgcgaa gcggtaggtg aacacccggt ccacccagcc cttgaggatg gcgggcatcg
       61 tgtaccacca cagcgggaac tggaagacga cggtgtcggc ccacagcagc ttctcctgct
      121 cggcgcggac gtccggggtg agcgtgccgg cgtcgaaggc ccggcccgag tcgagggcga
      181 ccttcagcgg gctcgaagcg tcggggccgt agtcggcggc gtccaccacc gccttccagt
      241 tcatcgcgta cagatcgctg acccgcacct cgtgcccggc gccctcaagc gtcgacaccg
      301 cgaggtcctt cagggatccg ttgagcgaat cgggctcggg gtgggcgtag acgatcagcg
      361 tcttcatggg gactcctggg gatcgggtgc tgccgatggc gcatcggacg ccttcgatcc
      421 tgcgtgccgc gccccgcgtt gttcaggggc gccgcttccg taggacggga cttcctggta
      481 ctgacagggc caggttcact ggcgccgccg aggtgatact gggggcatgg acgatcttgc
      541 gggcttcctg cgaacccggc gttcccgtgt cgaccccgcg gtcgccggca tccccaccgg
      601 cagccgccga agggtcgcgg ggctgcgccg cgaagaggtc gcgcacctgt ccggagtcag
      661 cgtcgactac tacgtacgcc tggagcaggg ccgcgcgacc cagccctccg agcaggtcct
      721 cgacgcgctc gcccgcgtcc tcggcctcga cgacaccgaa cgcggccacc tctaccgcct
      781 cgcccggcag caccgccgcc gcgcgaaggc gccggccggg cgcgtccggc ccgagctgag
      841 gcgcgtcctc gacctcgtca ccgacgcacc cgcgctgatc atggaccacc gcctcggcgt
      901 gctcgccggc aaccgcctcg ccgcgctcct gtacggccgc cccctgtccg gcctcaacac
      961 cgcccggcac atcttcctcg aggaagcgga gcgcggcctc tacgcggact gggagaagtg
     1021 caccctcgac gtcgtcggcc acctccgcct cgccgccggc aaataccccg acgacccccg
     1081 cctcgcctcc ctcatcggcg aactcgccat gggcagcgag cgcttccgcc gcctctgggc
     1141 ccgcgcggac gtacgcgccc gcacccacgg acgcaaggcc taccgccatc ccctcgtcgg
     1201 actcctggaa ctccaccagg agaacttcgc cctgcccgac ggctccggaa tggaactgct
     1261 cgtcctctcc gcccctcccg ccggccccac cgaggacggc ctacgcctcc tcgcacgcct
     1321 ggacgcggac agcgatgcct cgccgcccgc gtcgcacgtc acccggatcg gggaaacgac
     1381 gtgaacaccg cctccgccga ggcggcgttc acgctcgctc gtcccgggag gtcacctcgc
     1441 gggcgctccg gacgtcagcg ccaccactgg cggctgtccc agtagttcag cgggtcgaca
     1501 ccgatctgaa gaccacggtc gtagtccgtg atgtaccacc ccgtcgccgc gtgcttgaga
     1561 cgccagacac cacggtcacc gtcccactcc tcggaccagc gctgccagac gttgccggag
     1621 cagtgctcca tgtacacgtc gtggtcgctg taggccgtca ggcagaagtc ctggtcggac
     1681 gtcgtcctca tcagccacgt tccgtcaccg agatcctgct cgtgccacgt ggtcccggcg
     1741 tttccgcaac ctcgcatggc gacgttgctc gggtagcccc agttgttgtc gatcgaggcg
     1801 aggcacaggt cggtgtaggc gctccgccag gtcacgtttc cgtcggcgtg agccgcagtg
     1861 gcggcgccca cggtcagggc gaatgccttg aacttgttca tggacagaca atctcagcgg
     1921 ccgccaacgg ctctccaacg gatctccaac gtcccttcaa cgggcgacga cggggcctcg
     1981 gcgggggcac ctgaaggatc acggacctgt gcgtcgacgg ggaggggcgg tcgggtgccg
     2041 cggggtgagt agggtcgggg tgcagcggcg ggttcagctc aaggtgtgcg ggctcggtac
     2101 ggccgccgat gtcgatgtgg cggtcgcggc aggcgcggac gccgtcggtc tggtgatcag
     2161 ccggaccagc gtgcgcgggc tcgaacggga tcgggccgcg cggctcgcgg tccacgtgcc
     2221 gcagggcgtc ctgtccgttc tggtggtgaa cgacacgccg gccgccgatg ccgcccgtat
     2281 cgccggtgag ctcggtttcg gtgcccttca gctgcacgga acggcctacc aggaggacga
     2341 cttcgccgtc gcggccggga tctttccgcg gctgtggagg gccacgtcgc tgagcgaccg
     2401 gcccgacacg cgcgtcggcg cctacggcga ggaggtcctc ctcctcgact cgccgcaggc
     2461 gggttccggc gaaccgtggg acctgtcgct tctcgagtcg ggccgccccc ggggcacgtg
     2521 gctcctcgcc ggcgggctca cgccggagaa cgtcgccgag gccatcggcc gggcgtgccc
     2581 ctggggggtc gacgtctcca gcggcgtcga gtcctcccgg ggcgtcaagg accaccagcg
     2641 gattcgcgcg ttcgtcgccg ccgcgaagga agccgccgtg gagcaggccg cctcgtaggg
     2701 atcctccctc gacgcgatgg gggtacggag tcgtggccgc gccgctccgt ccgcgtcagg
     2761 cggtcggggc gggccaggcg acgtcgcttt cgacggcggc cgtgtagtcg atgccgggga
     2821 cggagaagcc gtacagacgg cggacctcgt cgctgaacca gtcgaggtcg gcgaggccgg
     2881 tgatggagtc gctggtggcg atggaccagc gttcggcgac ggcgttctgg acggtggggt
     2941 cgagctccca ggtgtcgagg cggacgcggc cctcgtcgtc gaggtcgagg gggcgggcgc
     3001 cggtgagctg gtcccacagc tgtaccagct ggccgatcgg ggcgatcatg ctgtcgccga
     3061 ggacgccgcg cagcagtccg acgtagaggg cgatgccggg gatggcggtg gaggactggg
     3121 tgacggccgc ggcgttgacg gaggtgacgg cccggccgcc cagggtcttg ccgaggcgct
     3181 cgtccagcgt gcgtgcggtg gcctccaggt gggacttggc cgcgccgatg gtgccctgcc
     3241 ggtagatcgc cgcggtgagg ggcgagccga tgtacgacag ggccgcggtg gtgaagccat
     3301 cggcgaggag ggagcggtcg gccaggaagg tgacccagcg ttcccagtcg gtgccgccca
     3361 tcacggccac ggtctgctcg atgtcgtccc cttcggcggg tccggtggtg acctccttga
     3421 cctcgggggc gccgtcctgg tcgaagacga gggtcttggt ggtgtacggc gagccgaccg
     3481 gcttgaggac ggaggcgtac acctcgccgg tgtccgggtc ggtgcggcga ggcgcggcca
     3541 cggagtagat caggtagtcg agccgtccgc cgaaccgttc ggcgaggagg tcggcgacct
     3601 cctccttcat cgcgtcgccg aaggcgtcgc cgttgaggaa caccatgtcc cgcccgtgct
     3661 gccgggcgag ccgggcggtg gcggccgtcc ggtaccagcc ggccgtcccg gtgcgccgcg
     3721 cgggcgcctt ctcgaagcac acgccgatgc cccggatgcc gatacgggcc aggcccgcga
     3781 tcgtggcggc caggccgtag cccgcggacg aaccgatgac cagcgcgacg ggcccttcgc
     3841 cgccgggcgc gaccggtgcg ggtacggcct gccacatgtc gtccaccacc tgccggcagc
     3901 cgccggggtg ggagtcgagg aagaggaagc cccggctctt gggcgcaatg acgcgttcgc
     3961 tcacggtgtg gtgtcccagc tgtcgtcacg tacaggatgc ggcggcctcc tgggccacct
     4021 cgtcttgcaa gtctgctgcc gcacggacgg gctcggtgat cttgaccggc acaacgatga
     4081 ccagccgggc ttggagggtt cccactaggt ctggcgggcc ggcggtccgt cgtggcgcgg
     4141 gcgatcgggc ggtggtcgga gcctgtgggt ggccggaccg cccggtgcgg aaacaccttt
     4201 cgtaaccgtt ttcgatcatc gtcgggcctc tgtgacccac gtcacggaat cggatttcgt
     4261 ctttccgtta tcggtgtccc gggccgaggc tctcccctgt gcaaggaact ccacaagagg
     4321 taagtgaagg acggacagcg tgcagcagac catgggtttt gagcagctga cggatgcgga
     4381 gctgatacgg gcggcgcagt ggggggctcc ctgggtgcga cagcacctgg tggccgtcta
     4441 ccagccgctc gtccacgcgc tggcggcccg agccctcgac ggccgggctg acgccgacga
     4501 ggtcgtgcgg tccgtcgtgc aggacaccct gggtcgcgcg gagttcacgc tggggaccct
     4561 gccgcaggtg gaggcggtac gcccctggtt cgtctcggtc gccgtggcga gcaccctctc
     4621 gcacgcggcc ggcgtccggg cacagcctgc cgtacgtgcc gggtcgggcg gggatcccgc
     4681 cggggtcctg ctctggctgg acgtcgagga cgccctgatg acggcgctgt ggtcgttgga
     4741 gcaggacggg tggctgagca ggtacgagac ggccgccgcg ctgagctggt ccgcgcacga
     4801 caccgcgacg cggatggaag cggtaggcgt acgaatggac cgggcgcggt ccgtgaccgt
     4861 cgcgctggcc cgcgaacccc gctgccccgc cctggcccgg caggtctcgg cctgggacgg
     4921 tcgcccgggc gccgcctggc gcgaggagct ggccgggcac accgtccagt gcgcccattg
     4981 cgccaccgga atcgtggcgg ccggaccttc ccgcgcgacg gcgacggcgg ctgtctcggc
     5041 cgtaggggca ggagggggaa tgccggcggc accgaccgac cacgccgcgt tcgacgcgtt
     5101 cgacacgttc gacaacctgg atgcttccgg cgctttcgac gcgaccggga cctacctcct
     5161 ccgccctcat cccgccgatc cgtccgctcc cgccggtcat gtcgccacgg ccgcggcggt
     5221 cggttcgcgc agcagccgtg cggcccggcg gcgacgtcgt caggccgacg agcgcacgcg
     5281 tcgccgtgcc accgtcgcgg ccgggatcgc cgtcgcggcg gtgaccgcgg gggccttctc
     5341 gctgcagtcg cgtgacgggg aggaccggct ggaggcgaac cgggccgccg ctccggggct
     5401 cgaccttccc ctggggaacg aaccgggcac gctgaccgcc tccccgtcga cggccgccgc
     5461 gtccccctcc gcgtccgcct cggccaccgc gaaaccgagc ggcgctccca cgaaggccac
     5521 ggccacgccc acgaagagtc cccgtccgac cacggcgacg ccggcgccga agcgcccgac
     5581 gaccccggcc gccacgacgg cggcgccgac gaggagcgcc acgcccaccg gcggcacgga
     5641 caccggtccg gggggcggtt cgcagcagga cacggggcag aagtcgacgg cggaccaggt
     5701 gatcgcgctg gtgaacgcgg agcgggccaa ggcgggctgc gggccgctca gtgccaacgc
     5761 cgcgctgacg cgtgcggccc agggccactc cgacgacatg gccgcacggg acttcttcga
     5821 ccacacgaac ccggacggcg acggtccggg gcagcgggtc acggccgcgg gctacccgtg
     5881 gtcgacgtac ggcgagaaca tcgcgatggg gcagaagacg ccggagcagg tcatggaggc
     5941 ctggatgaac agccccggtc accgggcgaa catcctcaac tgcgacttca aggagatcgg
     6001 catcggcatc cactcctccg gcggccccta ctggacgcag gtcttcggcg cgcgctgacc
     6061 gcccgtaccg cccaccgctc caccccgctc ccgggtcccg gcacccgtga gcggggccgt
     6121 ggagcgggtc agggcgtgtc gccggagtgg tggaaacggc acacgatgcc ggggccgggt
     6181 ctacgggctt cgccggggcg cgggtcgtac agggagcgcc caccgggcca ctgccccagt
     6241 tcggtggcca gcgcggcacc gtcgtcgacc tcctcgggcc gccagcccgt gacgtccagg
     6301 agcagaccgt ccagtggtcc gcccacgagt accgcgtagc tctgacctgg gagggggccc
     6361 gggtcggggt cgtcgtggtc gtggccgtag acccggccgc gcaggagctg ctcatcgccg
     6421 ttcatccctc cagccttcca gccgccactg acaacgcgag tcggtgacgg tgggcagggg
     6481 aagggcggac gagcagggga agggcgcacg ggcaggggaa gggcggacga gcaggggaag
     6541 ggcgcacggg caggggaagg gcggacgagc aggggaaggg cgcacgggca ggggaagggc
     6601 gcacgggcag ggccgcggcc gccgcccagc cgggcggtgg ccggcccacc gcggtgcggg
     6661 cagggggcag gccggagagg gtgtgacccg gcgggcggaa aatcgttcga tcgggcgggg
     6721 cccgtcgttc taaggtcggc gacgtggcaa cgaaactcaa tcagatcatc gcagtggaga
     6781 agggcgtcaa gtcccgggcg caccaggacc tgacggcggc tcatcacggc ctgcagaagc
     6841 ccgcgttgct cgccggcatc tcccgtacgt accagccgaa ggacgaggag ggcgagcagc
     6901 tgccgcccga gtcgacgctg gtgcaggtga aggccgagga cgtgctgcgt gacacggccc
     6961 gggcgctgac ccggctgttc gatgtgacgg ccaccaagga ctgggcgaac tgcgacgcgc
     7021 gtgcggacgt cacggtcgac gggcgggtgc tcgtggcgca ggtgcccgtg gcgtatctgc
     7081 ttttcctgga gaagcagttg acggacatca gcaccttcgt ccgcaagctt ccggtgctgg
     7141 acgccgccga gtcgtggacg caggacccgt cgaccgacgc gtggaagacc gaggtcgtgc
     7201 gcacggtccg tacgaagaag gtgccgcgca accacgtcaa ggcggaggcg acggacaagc
     7261 acccggcgca ggtcgaggtc tactacgagg acgtgccggt cggctactgg acgacggtga
     7321 agttctcggg cgcgctgccg gcgcggcggg tcaacgaact gctgacgcgg gtggagaagc
     7381 tgcagcaggc ggtgaagttc gcccgcgagg aggcgaacag cgccgaggtc accgaccagc
     7441 gggtcggcga cgccgtcttc ggctacctct tcgggtagcc gggacaccac agactccccg
     7501 gccacggaag acggccgggg tgcgcgagga gcgcaaagct gaagctgagc cttgtcgtga
     7561 catccgcggt tccagtggag gttcgagtcc tcctcccggc actcctgccg gggtggccca
     7621 accaggcaga ggcagaccgc ggtcaatctc agactattgc tccagactca gcatgcgccg
     7681 ctcatcgccg gatcgaccgg gcccgggccc aggtgcgtcg aaatgccagt tcgaatctgg
     7741 tccgccgagc tcgatcggcg gtggtccaaa ggcaggacgc gacgcaatga cgaatgaccc
     7801 gggttctcaa gtgtgccggc gtgtgatggg agcggcatcg acagggtccg ggggcaggct
     7861 acgccctcgg acccgctcct tttcccctgg cttgcggtac ggttcggcca ggggacggct
     7921 cagctgggct gggccgtggg catgatcgtg atctgctgga ggttggcccg cggcgggagc
     7981 gtcgcggcga agccgacggt gtgtgcgacg tcggcgggcg tgagccactc catggcctcc
     8041 ttggcgtctt cgagccaggc gagggcgcct tcgtcggtga cgtggctctg gagctcggtg
     8101 gcgacgatgc ccggctcgat cgcggagaca cgcacgttct tggcgcccag ctcggcgcgc
     8161 aggtgccgcg agaggtgggt gacgtaggcc ttggtcgcgg agtagacggc gaagttcggg
     8221 aagatgttcc gcgccgcgat cgacgaggtg ttgatcaggt ccgcgacacc gcgctcaccg
     8281 gccgccgtga ccagttgcgg ggtgaaggcg ccgatcacgt tcatcaggcc ggtgatgttc
     8341 aggtcgatct ggtgctgcca ctggtcggtg gcgagctcct cgacgggggc cggcagcatc
     8401 acgcccgcgt tgttgaacag caggtcggcg ccgccgtatt cggacgcgac ccggtccgcg
     8461 gcggcctgca cggccgacgc gtcggtcacg tcgagcgcca gggccagcgc ttcgccgccg
     8521 ttcttctcga tccgggcgac gagcccgtgg agacggtccg cgcgccgggc caggacgacg
     8581 accttcgcgc ccagttcggc gaggtgctcg gccgtggcct cgccgatgcc gctggatgcg
     8641 ccggtcacca ccgcgacgcg gccggcgagg gggtgggagg acgggtacgt ggtcatggag
     8701 tacgcctttc gaggcggagg cgggtgagtg ggtgacgcgg tgtcgggtcg ggcggagtcg
     8761 ccgcggcgtt cccgtcggcg ccttctcaag aacatcaccc gcgggcgcct cgtcgagcgc
     8821 cgcaagcgtc cctgaccagg ccggtatccg tgaggcaggt accggcagta ccacccgcgc
     8881 gccccgtcgg ggccccgctc gcccggcaca ctgggggcat ggacgaacgt ggtcgcgagc
     8941 tcgccgattt cctccgcacc cgccgtgccc gggtgaccgc cgaccaggcg ggactgcccg
     9001 atgacggccg ggtacgccgt gtgccggggc tgcgccgcga cgaggtcgcc cgactggcag
     9061 gcgtcagcac cgagtactac acccgcctcg agcagggccg ggcccagaac ccctcccccg
     9121 aagtcgtgca ggccctcgcc gacaccctgc ggctcgaccc ctccgagcgc gagcacctca
     9181 ccgatctctt cgcccggccc acgccggccc gccgcgctcc ggtcgggccc cagcgggtcc
     9241 gccccgggct gcacctgatg ctggggaccc tcggtcacgt cccggcgttc gtcctcggcc
     9301 ggcgcaccga cgtcctggcc tccaaccgcc tggcacgcga ggtcctcacc gacttcgacg
     9361 ccctgcccgc gccccgccgc aacctggccc tctactacct gctggatccg gaggcccgtg
     9421 tccgcgtggg cgactgggag cggatcgccg ccgagaccgt cgccatcctg cgtctggagg
     9481 ccggacgcgc cacccacgac cgtcgactcg ccgacctcgt cggcgaactc acgctcaagt
     9541 caccggagtt cacctcctgg tggaacgacc accgggtcct ccgccgcacc cacggcgcca
     9601 agcactatcg ccaccccctc gtcggcgacc tccacttctc ctacgagtcc ttccaggtcc
     9661 ccggcgacac cgaccagacc ctctgcgtct acaacgtcga gcccggctcc gacaccgccg
     9721 aggccctccg tctcctcacc agctggaccg caccccagac cgtgcggtca cgggcgtcgg
     9781 agccgggggc ctagggggta cgcgacgggg ccggagactc cgtcggcctc gcttccgggc
     9841 gtgtgcgcgg gcgcttcgtg ttgcgccggg cgcgccggtg ggtggaggga aagcgctgtg
     9901 cgctcgctgg atgaagtgaa tatgacgggg agcgtgttgg tgtggttatg ccaccgggaa
     9961 cgttctcgcc agcggttctc agcgtggaga gggagacgca atggcgagcc acattaccga
    10021 agtcgacctg gaaggcgttc tgcgccgagc gctgcgggcc acgggcacgg gggcgcgttg
    10081 ggcggcggag gcggacgaga tgtggtgccg ggtcgcgacc cgggcagggg tgcggcgcga
    10141 gcaggggtgg aagctgcacg tgtcggcgac ggtcgcttcc gcgccggagg ttctcgacag
    10201 ggccctcggg gtgctgttgc gcggggagtc ggggttcaag ttcgcccggt cgctggagca
    10261 ggtgggcgtg ctcaactcgc gtgcgactcc gcggggcagt tcggggaagt tcatcaccgt
    10321 ctacccgtgc tccgacgccg aggcggccgc cctcgccgag cggttgcacg cggcgacggc
    10381 ggggatggcc gggccgcgga tcctgtccga ccagccctac gccgtacgca gcctggtcca
    10441 ctaccgctac ggggcgttcg tcggccggcg gcggctgtcg gacgacggcc tgctcgtgtg
    10501 gttcatcgag gaccccgacg gcaatcccgt ggaggacaag cggacgggcc ggtacgagcc
    10561 gccgccatgg gcggtctcgc cgttccccgc cgtgacgccc gctccgtcgc gcaccggcga
    10621 gggggacgag ggcggtgtgg tgctcggtgg ccggttcgcc gtacgggagg ccatccggca
    10681 caccaacaag ggcggtgtct accggggcag cgacgtccgc acgggagccc ccgtggtgat
    10741 caaggaggcc aggccgcacg tcgaggccga cgcctccggg tgcgacgtca gggactggct
    10801 gcgggccgag gcccggatgc tggacaggct gaagggccag gggctcgctc cggagccgct
    10861 ggcgttgttc gagcacggtg ggcacctgtt cctggcccag gacgaggtgc cgggtgtgac
    10921 gctgcgcacc tgggtggccg agcacttccg cgacgcggga ggagcgcgtt accgcgccga
    10981 cgcgctgctc caggtggcgc ggctggtgga cctggtcgag gcggcgcacg cacgcggctg
    11041 tgtgctcagg gacttcacgc ccgccaatgt catggtccgg cccgacggtg aactgcggct
    11101 catcgacctg gaactcgccg tccacacgga cgaggccgcg cttccgaccc gtgtcgggac
    11161 gcccggtttc agtgctcccg agcgcctcgc cgacgcaccg gtccgtccgg cggccgacta
    11221 ctacagtctc ggcgccaccg cgtgcttcgt cctggccggc aaggtcccca acctgctgcc
    11281 ggaggagccc gcggggccgg ctgccgagca gcggctcgcc gcgtggctca cggcctgcgc
    11341 cggtccgctc gatctgccgg acggtgtggt ggagatggtg ctcgggctga tgagggacga
    11401 ccccgccgag cggtgggacc cggtcagggc ccgtgaggct ctgcggaggt cgactcgtac
    11461 agcgacggga tccgtggccg tagggcccgc ggcggtggcg tcccgggccg tcgagcccga
    11521 cgtcgggtcc gtggtggccg ggctcgtgga gcacctgatc gggtcgatga ctccggacga
    11581 cgaccggcgg ttgtggcccg tgtccacgac ggccggggaa agcgacccgt gcaccgtgca
    11641 gcagggcgcg gccggggtgc tggccgtcct gacgcggtac ttcgagctca cgggcgaccc
    11701 gcgactgccc gaggtgctgt ccaccgcggg ccggtggatc gcgggccgcg ccgatgcgcg
    11761 gtccccgcgc cccggtctgc atttcggggg gcgcgggacg gcctgggcgc tgtacgacgc
    11821 cgggcgtgcc gtcgacgacc gtgcgttgac cgaccgagcg ctggctctgg cgcgggcgcc
    11881 gcagcaggcg acgccgcatc acgacatcac ccacggctcg gcaggcagcg ggctcgccgc
    11941 actccatctg tggcagcgca cgggtgacgc gcgttgggcg gagttcgccg tcgaggcggc
    12001 ggaccggctg accgccgccg tgcggcgggg cccggacggg gtggggtggg cggttcccgc
    12061 ggaagccgtg gatccggacg ggggctcgtc aggggacgcc tcggccggag gtggcaagcg
    12121 ctacctgggc ttcgcccacg ggacggccgg gatcggctgc ttcctgctcg cggcagcggc
    12181 ggtctcccgt cgccccgcgc acagggaact ggccgtacgg gtcggtgagg gtctggtggc
    12241 gagcgccgta ctgtccggcg aggcggcgca gtggccggcg caggccgggg acctgcccac
    12301 ggctccgtac tggtgccacg gctcggcggg catcggcggc ttcctcgtgc ggctgtggca
    12361 ggccaccggg gacgacaggt tcggcgatct cgcccgtcgc agtacgcggg ccgtggcgga
    12421 acgcgcctcc cgcgctccgc tcacccagtg ccacggcctt gcgggcaacg gcgacttcct
    12481 cctcgacatg gccgacgcca ccggtgatcc cgcgtaccgc tccatggccg gggaactggc
    12541 ccgcctcatc gtctgcgaga agaccgaccg tcgcggccag gtggtgttcc ccaacgagta
    12601 cggggacgtc tcgaccagct ggagcgacgg gtccgccgga atcctcggct tcctcctgcg
    12661 gatgcggtac gccggcacac cgcggcactg gacggtccag ccaccggcct gagtccgagg
    12721 cccgggtggg ccgaactctc tcccctcctc gcagcctcct gcgagttcct cccccacggg
    12781 tacggggacg tcatcccggc ccggtggaag gacgcgtccg caacggaagg tcggccttcg
    12841 tcctgcggat ccgtcacacc gacccccggc actggatcgt ccagatgccg gtgtgagcgg
    12901 cagcacgttc tgtcgccacc cccaccagag aaggagaaag ccatggagaa ccacgacatc
    12961 gacctgctgg cccggctgca cgcccttccc gagaccgacc ccgtcggcgt cgacggcgcg
    13021 ccgttcgccg ccacctgtga gtgcatcggc ctcctgacgc tcctcaacac ggtctgtatc
    13081 gggatcagct gcgcgtagga ccggcagcac catccggccg gcggtcgaac ccgggacagc
    13141 cgccggccgg acacccgacc cgatccacag cgcggccgcc tggggcctgt ccggccctga
    13201 tccgccggac aagcttctag cggccgcgcc ccctcttcac actccgcccg gcctcgggca
    13261 cgccgtccgc ggtgcgccgg ggcgcgctgc gtgacctcgc cgcgcgcacc ggcggccgcg
    13321 gtcggcggat ccgtggacga ggaccggcag acgaggacga gcaggcgagg agcagcccat
    13381 gcagccacac gtcggtgacg acgaccaccc tccgacggcc ctcctgacgg ccgctcccgc
    13441 cggcccgcgc ggtgcccgac accatcccga gcccgtgtcc gcgatcaccg cacgcgctct
    13501 gggcaagagt tacccgggcc ctgaggacgc cgtcacgcac gccgtgagcg gcctggacct
    13561 ggacgtggcg gcaggcgaga ccttcgcctt cctcgggccc aacggcgcgg ggaagtccac
    13621 caccatcgcc ttgctgtgtg ccctggcacg ccccaccgcg ggtcgcgcca cggtggccgg
    13681 ggccgacgtg ctcacccagc cccacttggt acgccgacgg gtcggcatgc tcttccagca
    13741 cagcgccgtg gacggggacc tgaccgccga gcagaacctg tacatccacg cccggctcta
    13801 cgggatgccc cgcggccagg tccgccggcg caccgccgag gtactggaga cggccggcct
    13861 gagcgaccgg cgccgctccc ccgtacgcac cctttcgggc ggcatgcgcc gccgcctgga
    13921 gatcgcccgc cagctgctgc acgcccccgg cgtgctgttc ctggacgaac cgaccaccgg
    13981 tctcgatccc cacgcccgcg cccaggtctg gcaccacctg cggacgctgc gcgagcggca
    14041 cggcagcacc ctgttcgtca ccacccacta cctggaggaa gcggagaact gcgaccgcat
    14101 cgccatcatc gatcgcggcc gactggtggc gcaggggacg cccgtcgccc tgaaggccgc
    14161 catcggcgac gaccgggtcg tcctgcgcac cggcgacgac accggggcgc accggatcgt
    14221 gcggaccctc gcgccgcccg gatccgccct cggcgcggac gccgccggcg tctccctgcg
    14281 ggtgcccgac ggcagctcgt ggatcccccg tctgtgcgcg gcgctgacgg cacaaggcat
    14341 cgccgtgcac tccgcttccg ccacgccgcc cacgctcgac gacgtcttct tccaccacac
    14401 cggccgcagc ctggaccccg cgcaaccggg cggtcccgcg cccctgcgcc cgtcgtcgcc
    14461 gcgcgccacg acggaatccg gtggcagccg atgaccgcac tcggccggaa ggcaccggac
    14521 ggtcccgccg ccggcccttc gggaacctcc cgtgccgcgg aggccgacgg caccggcgtc
    14581 gccgcaggcc acggacggtt cacgaggccg cggcacgagc tgcgcgcgat ccacgcgctg
    14641 gtccaccgcg atctgctccg gctgggcggc cagcgcaccc acacggcgct gatgctgctc
    14701 cacccggcgc tctacctgct catcctcgga gggggactgg cctcgctcat cccccggtcc
    14761 caactgggcg tcggctacca ggcgtacctg ttccccggga tgctgatgat gacggtgcag
    14821 accccggcca tcatggtcgg cgtccgtctg atcaccgacc ggcagagtgg ctacctacgg
    14881 gaactcctga tggccccggt ccaccgctcc acccttctcc tgggcaactg cgcgggcggc
    14941 acgctggtcg ccacggcgca gggagcggtg ctcctcgcgc tggccggcgt ggcgggcctg
    15001 ccgtacgacc cggtgctcct ggttctgctg ctcggctgca tggtcctggc ctcgttcacc
    15061 gtcaccgccc tggccctggc cctggcggtg agcctgcaca gggcggagac gttccacacg
    15121 ctcctggggg tggtgatgat gccgctcctg ttcctctccg gtggcttctt ccccctcacg
    15181 gtcctgcccc gctgggtcca cgtcctcgcg gacgcgaatc cgctcgccta cgccgtggac
    15241 ctcctccgcc gctgcatctc cctgcgcgtg ccggatcacg cggccaccgc gggcctcgac
    15301 tgggccggcc gccgacctcc gctgctgctc gaagccggcc tcctcctggc ctgcggcgcc
    15361 cttgccctgc tgtgggcggc ccggcggttc aaccgcccgg aatgacctgg gccttcgggc
    15421 cggtgacgag ggtgtcgacg gcggtgtacg tcactccgtg gtcggcgagg gcctcggcga
    15481 cgacgcctcc ggtcatggtg agcgcgagga ggatgtgttc gtcgccgatc tcgcggtcct
    15541 tgcgggcgag cgcgacgcgg agggacttct ccaggacggt cttggcctcg cgggagaagg
    15601 tctggcgtcc cgaccaccaa ccggggtcct tgcggtcgcc cgcgagggcg cccgcgccgt
    15661 gggcctcctc cacccggtcg acgatcgcgc cgacgtcgat gccgaggtcc gcgagggcct
    15721 gggtgtcggc ccgggagagt ccggcccggc gccgggcggc ggcgagtgcg gcggtgaggg
    15781 acgggcggcg gtccggtggg cagagcgttc gcagcgcggc cgccgcgcgg gtgtcctgcc
    15841 ggtcgagcag ggccaggagg aggtgttcct tggtgacggt cttcgtgccg tcccgctccg
    15901 cgtgctcgac cgctcccttc acgacggcac gtgcggcctg ggtgaaccgt tcgaacatca
    15961 ctgcctcccg tacttcttgt ggacggcctg tcggctgact cccagttcgg ccgcgatttc
    16021 ctgccacgac cagccctggt tgcgcgcact gcgcacctgg acggcttcca gctgttcgag
    16081 cagtcgccgc agcgcggaga cggctcgcag cccgacccgg gggtcgcggt cgcccgctct
    16141 cgcggcgaga tcggtcgcat cggtcatgga tgtcaactta cgttgacaga gtcgtcgtgt
    16201 caacctcggt tgacacgact cgggcggcgg ccggggttcg ccggaccgcc gcccagcggt
    16261 cgcacccggg cggcgggcac gacggccgag gtcgctaacc tgacccggaa tcagaacggt
    16321 tttctggaag ggagttccag aaaaccgttc gcgtcgccac gggggtatct gatgtcgcag
    16381 tcgcacgagc cctggtacag gcaccggccg ccgccctggc ccgtgccgga caatccgtac
    16441 gcccctgagg ggtacgggcc cccgccgccc ggtcggcgcc gccggtggcc ggtgctcgcg
    16501 gcgggcctcg tgctgctgct cctcgtcggt gcgggcggtt acgtgctgac gcagcacggc
    16561 ggagcggggc gcacgccgcc cgtcgcgcag gggacgaccg ggccgccgaa gacgacgggc
    16621 actcccccgc cgacgacgaa gcccacggcc gcgccttccc acatcccgac caccgcggag
    16681 atcgcgcgac agcaccgctc cggcgaggcg agtgcctgga tcgtcgacga ccgcaccgac
    16741 ctcccccggc gcgacatccc cctccaggac ctgtggatcg tgggtgacac ggccgtccag
    16801 gccgtctaca agagggtcgt cgcgcaccgg ctgggcgacg gcgccgagct gtggagcgtc
    16861 gcgctgccga cgcccgtctg cgagaccccg gtccatccga ctcccgacgg caaggtcgtc
    16921 gtcgtcctca agaacgtcga ggcgtggacc ggagcccggt gcaaccagct ctggatgatc
    16981 gacctgcgca ccggcaaggc cggctggcac aagcagctga ccgagacggg ctccggagac
    17041 gacaccatca tggtggacag cgccgtgagc ggcggcacct tcgcgatcgt ccagagcatg
    17101 aaggccaccg cgtaccgggt cgtcgacggg cggaagctgt acgacatccc cctggaggac
    17161 cccgggaagt gctaccccgg cagggtggcg ggcggcagcc gcctgctcgt cgtctccgac
    17221 tgcgcgatca ccgcgctgga gaagtcgtac agccagctcc gggagatcga tccggccacg
    17281 ggcaaggtca ggtggcgcta ccggaccgag ccggggcacg tcatcggcca ggtgctcgcc
    17341 gtcgacccgg ccgtgatcac caccgtgcgc aaggagacga gcggagcgga ctggcgggtg
    17401 gtcgccctcg ggcccgacgg ccgcgtacgc gggacggtcg acccacgggc gaagggattc
    17461 acccactgcg gggactcggt ggacacctcc ggcgacgccc aggcctgccg ggaagccgtc
    17521 gtcggggcgg gcctcgtgct cctgggcggg accgaccgtg tcggcgccta cgacctggcc
    17581 accgggaagc cggtctgggg cgtgaagtcg gaggggacct cgtacggcta cttccccctg
    17641 cgcgtcgggc cgggcaggac ggggctggtc tatcgggtgg ccgcgctcgg agaacccgga
    17701 cgcgtgttcc gggtcggtcc gggcggtgtg gacacgatca aggacgtgct gaagctgccc
    17761 gcggccacct ctcggctcga gttcggcatg ggggtcgtcg ggaggaacgc ctacgtgggc
    17821 gaccggctcg tgctcgcccc caggggcatg agcggcgacg acgcccagca cgaaccccgc
    17881 atgctctcgt tcgcgccctg accccacgcc tcagggcgca ccgggaagcc ggaccgtgac
    17941 gaggagaccg ccggcggggc gggcggcgag gtcgagggtc ccgtcgtggg cccggaccac
    18001 gctgtgcacg agggcgaggc cgaggccgac gccggggtgc tcctccgtgc gtgcgcgctc
    18061 cgccccgcgc tggaagggct cggtgagggt cggcaccagt tccggaggga gccgacggcc
    18121 cgtgttctcg acccggagca cactcgtggt gccctccgcg tcggtgcgga ccgtgacggt
    18181 gccgccggcg gggaggttgt ggacgacggc gttctggacg aggttcgtcg ccatccgcag
    18241 caggagttcc gcggatccgg tggtccatgt cggtccgccc gtgacgtcga gcgtgatccc
    18301 acgccgttcc gcgagcggga gcaggctctc ggcggcctct tcggcgacga gggagaggtc
    18361 gacaccctca cgggtgaagt ggccccggtc gctccggccg agcagcagaa gggcctcggt
    18421 gaggtcgatc gcgcgcgtgt tgacggcctg caggcgggcg atcagctcgt cccggtcacg
    18481 ggtggggtcc ttgcgtgcga cgtccaggag cgtccgggag atcgccagcg gtgtgcgcag
    18541 ttcgtgggag gcgttcgcgg cgaacctctg ctgttcggcg acgtgcgact cgagccgctc
    18601 cagcatcgtg tcgaacgcgt cggcgagctc ccggaactcg tcctgtcggc cctccatgcg
    18661 gatccggtgg gacagcgagc cgctcgcggc gctccgcgcc gcgtccgtga tccgcgtcag
    18721 cggtgccagc atccgccccg cgaggatcca tccccccacg agcccgaaca ggagcaggaa
    18781 cgccatcgcg gccgctgcgg cgggggcgaa ggtgcgcacg aggaggtagc ggttgggcga
    18841 gaccccgagc agaccctggg agttgtcggg gacgtaacgg agcaggaagg cccacaccac
    18901 gaccagcagg agggcgccgg cgagggcgag gaacccggcg tagctgaggg tgagtttcag
    18961 tcgggcgctg agccccgggc gtctacgcat gcccgctgcc gccgggggcc gtggcgtcgc
    19021 cgccgccagg gtccgtggtg gtgccgccgt cggggtcggc actgcccgta cggggctccg
    19081 caggtgtgtc cgcaggtgtg ttcgcggcgg ggttcgtgcg ggtgtcgatg cggtagccga
    19141 cgccggggac cgtggcgatg atccagggtt cgccgagccg cttgcgcagt gccgagacgg
    19201 tgatgcgtac ggcgttggtg agggggtcgg cgttctcgtc ccaggcgcgt tcgaggagct
    19261 cttcggcgct gacgactccg ccctcggcgg cgacgaggac gtcgagcacg gcgaactgct
    19321 tgcgggtgag cgcgacgtag cgtccgtcac ggaagacctc gcggcggaag gggtcgagcc
    19381 gcaggcccgc gatcttgcgg accgggggcc gggcgtacgc gcgtctgcgg tcgagcgccc
    19441 tcagccgcag gacgagctcc cgcaggtcga acggtttggt gaggtagtcg tcggcgccga
    19501 gctcgaaccc ggacgccttg tcgtcgatcc ggtcggcggc ggtgagcatg aggatcggga
    19561 tgccgctgcc ggaggcgacg atgcgccggg cgacctcgtc accggagggg ccggggatgt
    19621 cacggtcgag gaccgcgagg tcgtaggagt tgacgctcag cagctccagg gcggtgtcgc
    19681 cgtcgcccgc gacgtcggcg gcgatcgcct cgagccgcag accgtcacgg acggcttcgg
    19741 ccaggtaggg ctcgtcctcc acgatcagta cacgcatgcc cgaagcctag gcagggcggc
    19801 atatcgccac cgtatgcgga ggtgcccgcg gcgccgtgtc ggtccgggcg cgcgccctca
    19861 gcccgccgct gccggtacgg ggcgctgcgg ttcctcgctc cgcgtcgcct ccggggtccg
    19921 ccaccagcgg cgcgaggcca gcgcggccag tacggcgccg gcggcgttga ccaggacgtc
    19981 gtcgacggag gacacccggt ccagacgcag gacgtactgt gcggtctcga cgaggaccga
    20041 gcagcccgcg ccgagagcca ggatccgcgg cacggacgcc agcgccgcga accgcatcgg
    20101 ggcgaagaag cccagtgccg cgaagaccag cagattgccc ccgatcccca gcggccccat
    20161 cgtgacgagg tcccgcagcg ggaccaggct cacccgtgcg gggacgacgc ccgctccgcc
    20221 gcccggcatc atggtcagcc acaggaacgg cagcgtcccg tggaccatgc ccacctccgc
    20281 cagggacgtc cgccacgccg acgcgtcgcc ggccgaacgc cgacggcgcg ccaggaccca
    20341 gaccacgagc agggccaggg gcagcgcgac cagcgtcatg agcaccacgc cgttgaacgt
    20401 gtcgtagcag ccgtgccacc gcccggccat gcacctcggc gcggacatca tgagcggtcc
    20461 ccgcacgacg aacaggccgc ccgccagggc gaggaccgcc aggcctacga gcacggtcct
    20521 gcccgtccgg ccgggccgtg ccgaagggga tgcgttgtgg ttcatgcccc catcgaaggc
    20581 ggagggccgt tgcgggggcg tatgcggttt tcgatacgcc cgcgatacac gcgtcggccc
    20641 gcgtcgtcct cgtcgtccgc tcaggccccg cgccggacgc ggaccgtcgc ccgccatccc
    20701 aggaccgtgc tcgccacgcc caccaggatg gccacgaagg ccccgcccag tccgttgccg
    20761 gtgccgaggc ccccgtcggc cgtggccgcg accagcacgc cgacggccgt gccgaccagc
    20821 cccgcgacca gggcgatcct ggctccgaga ggtccgctcg cgacgccgaa gcggccggtc
    20881 gggcgggcca gggccagcca tccgacgacc acgccggcca gtgcgaggaa cgcggccgcg
    20941 gaagacccgg cgcgcccggg gccgaagtcg tagacgctcg cggcgagcgg ctgcgccgag
    21001 gcgacgtgcg cggccgcggg tgcggcgaac gcgaggcttc cgagcactgc cgcggcgcac
    21061 gcggcggtga cggtggcgag cggtcggcgg gcggacggtc gagtggacat gagcggtgct
    21121 ccttcgtgcg tcgggttgtc gtccgagcat ctccgccggg cccgttccgc gtcgtccggc
    21181 gggcgcaggc acttcgcact gccgccgccg tcgcatacgg gtaccgcgga cgccgcagat
    21241 cgcgaggagc tactgcgtgc gtggtagacg gcggtcgtct gcgggggtga ctcgccgacg
    21301 gcggcggccg gttagggtgc gcgcatgagt gcaagtacgg cccggatgtg ggcccggttc
    21361 ggtgacggag tcatcgccgt gggcgtggcg gcggcgcttg tcgtcacggg actgtcgcag
    21421 cgggttcccg tctccggtca ggccgtcgtc gggtacgcgc tgctcgcgct cggcgggctg
    21481 gcgctcgccg cgcggggccg ggcgccggtg gccgtgctgg tcgtcacggg cgtgtgcgcc
    21541 gcggggtacc aggcggccgg tttcgacgtg gcggccgtgg cgtacctgtt cgccgtgtac
    21601 ggggccgtgc gggcggggca ccgcaccgtc gcggtggtgg cgagcgtcgt cgtgctggcg
    21661 ctgcttccgc tcgcggcgct ggcgtcggga tcgcacgaca cgggcgaggc gttcgcgcag
    21721 gcccggggcg cgctcgagat cgcctggctc gtcgcggcgg gggccgcggg agaggcgctg
    21781 cggcaggccg agcagcgggc ggaggaggcc gagcgcaccc gcgaggagac cgcgcggcgg
    21841 cgcgccgacg aggaacggct gcgcatcgcg cgggaactgc acgactcgct cacccatcag
    21901 atctcggtca tcaaggtcca ggcggaggtc gcggtgcacg tggcccgcaa gcggggcgag
    21961 gacgtaccgg cgtccctgct ggcgatccag gaggccggcc gcgaggcgag ccgggagctg
    22021 cgtgccactc tcgaggcgct gcgcgacgac gacacgaccc cgccgcgcgg ccttgacgac
    22081 gtcccggagc tggtgcgacg ggcccgtacg ttcggcctgg acgcgacgct gacggtcgag
    22141 gggacgcacc gcgacgtgtc ggccgcggtg gaccggaccg tctaccggat cgtgcaggag
    22201 tcgctgacca acgtcgcccg ccacgccggc gccaccacgg cgtcggtccg gatcgactgc
    22261 cggccggaca ccctcgagat agcggtggtc gacgacgggc gggccacgac cggcgccgcc
    22321 ccgacgccgg gcctcgggct ggtcggcatg cgggaacgcg tcacggcgct cggcggccgg
    22381 ctgcgcgccg caccacgtga cgggggcggc ttcgccgtcc gggccgaact tcccgtggac
    22441 cgggcgtcgt gatccgtgtc ctgctggtcg acgaccagcc cctcatccgc agcgggttcc
    22501 gcgctctgct cgacctcgag gacgacatcg aggtcgtggc cgaggccgcc gacggcgccc
    22561 ggggcgtcgc gctggccaag gagcacctgc ccgacgtcgc gctcgtcgac atccagatgc
    22621 ccgtcgtcga cggcatcgag gcgacccggc gcatcgtcgc ggacccggac ctcgccgggg
    22681 tgcacgtggt catcctcacg aactacagct tc
//
