LOCUS       NZ_JH947126            20975 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Pedobacter arcticus A12 Scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_JH947126
VERSION     NZ_JH947126.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pedobacter arcticus A12
  ORGANISM  Pedobacter arcticus A12
            Bacteria; Pseudomonadati; Bacteroidota; Sphingobacteriia;
            Sphingobacteriales; Sphingobacteriaceae; Pedobacter.
REFERENCE   1  (bases 1 to 1024955)
  AUTHORS   Yin,Y., Yue,G., Gao,Q., Wang,Z., Peng,F., Fang,C., Yang,X. and
            Pan,L.
  TITLE     Genome sequence of Pedobacter arcticus sp. nov., a sea ice bacterium
            isolated from tundra soil
  JOURNAL   J Bacteriol 194 (23), 6688 (2012)
   PUBMED   23144423
REFERENCE   2  (bases 1 to 1024955)
  AUTHORS   Ye,Y., Peng,F., Xu,Y. and Chengxiang,F.
  TITLE     Genome sequence of Pedobacter arcticus A12, a sea-ice bacterium
            isolated from the tundra soil
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 1024955)
  AUTHORS   Ye,Y., Peng,F., Xu,Y. and Chengxiang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2012) China Center for Type Culture Collection
            (CCTCC), College of Life Sciences, Wuhan University, 16 Luojiashan
            Road, Wuhan, Hubei 430072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. May-2012
            Genome Coverage                   :: 253x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000302595.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 09:54:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,583
            CDSs (total)                      :: 3,537
            Genes (coding)                    :: 3,512
            CDSs (with protein)               :: 3,512
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 6 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 4 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 938113
            Orig. end                         :: 959088
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JH947126.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10975
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    205..218
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     tRNA            complement(665..738)
                     /anticodon=(pos:complement(938815..938817),aa:Pro,seq:tgg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="B176_RS0111150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Pro"
     gene            complement(665..738)
                     /locus_tag="B176_RS0111150"
     misc_feature    793..806
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     gene            994..1722
                     /locus_tag="B176_RS0111155"
     CDS             994..1722
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003003058.1"
                     /locus_tag="B176_RS0111155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(Fe-S)-binding protein"
                     /protein_id="WP_017258894.1"
                     /transl_table=11
                     /translation="MNVELFIPCFVDQLYPETAKNTYKILQKAGCNVIYNPEQTCCGQP
                     AYNAGFWDDAKEVGSKFLNDFSEQNYIVSPSASCTGMVKNSYNDLFFNTSIHNKCRNIQ
                     SHIYELSDFLINVLKKDYFGAELLGKAVFHDSCSGLRECNIKEEPRKLLSKVLGLEVVE
                     MKDSDVCCGFGGTFAVKFDGISTAMAEQKVQNALDTGAEIIISTDTSCLLQLQAYIDKN
                     NIQIKTMHLADVLATGWGNV"
     gene            complement(1696..4380)
                     /locus_tag="B176_RS0111160"
     CDS             complement(1696..4380)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024180.5"
                     /locus_tag="B176_RS0111160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_154647953.1"
                     /transl_table=11
                     /translation="MARISIFIFCIFITFSTTFGQNTDAVFQKKLSVFKTEDSLAKWID
                     SRVDFALIQPSERLLFLMQTNKLAWRAPKTQQENESWLFLLVNQGYYQLQNGDILASIT
                     CYENAYEFSEKHPTGLDIEEYILKPLSNNYTRLGDYERAIYIQKRSLNLALKQNKLDLA
                     TSAYCNLSTSYRSKNDLRNAEQSALAGLKIADKKSAIYGLLLSNMADISNENKDYAKAE
                     GFVSTAIRHLKLQKLNSSTAYWLLSAYTLAGDIQLNQENLESAKNFYKNAQKLIYSLLG
                     GGRKRELTYLINQLGSVYLVQKDYQQALSQYNQALIYLLPEFKLLKPNDLPDERTLFGE
                     NKLQAALMGKAEVLARLGDKKQSLQASILAFAVAEELRKEYTYDVSKERLQAESKALAE
                     LVIEKSYELWVKTKDAVYANHILMFSEQTKSRILFDELNASQSSDSKRKKNPLQQQKIK
                     IQQLLSYYQKQKQSNSNTVILKKIADLEFQLSSLQKQLNQKNPSLTLKATQILQKIPVE
                     KQAIIFFCGDRNSYMIIANHHKVSQVIKLGTTKQLSASVGHYLEKYFYNGPAEMINNPQ
                     AFYNASNNIQKLLFSQVNINNQKVLLIKDGILNFLPFESLITESGVAKNVAQWPFLIKK
                     VEISYGFSLSSIPSVKRSKTAYRYQFTGIFLSRTGSSKNEIPAVVAEYDALKRFIKGDF
                     FKNEDATVDNFKQAINHSDILHLSSHSYLTDSLKEPVLELYHDRFYLLELASQQKVPEL
                     VVLSACQTADGAYLSGEGVLSFSRGFIAAGSKGVISSLWNVNDQSGADLMVNYYRTLLQ
                     RKTTAGTLAKTKLQWLKQKHKNQMVLLPYYWDSLIYTGEDFGVTIEEPGHFLVYSGVSL
                     SILLGIVVFFYRKKRLNISPTRG"
     gene            complement(4409..6421)
                     /locus_tag="B176_RS0111165"
     CDS             complement(4409..6421)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258896.1"
                     /locus_tag="B176_RS0111165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PKD domain-containing protein"
                     /protein_id="WP_017258896.1"
                     /transl_table=11
                     /translation="MRKFLVYIIIFFFGFAVDKANAQVHPTDTIPVKINYAFKGDSVRF
                     TSELRPLRPIAGAPEPFYTYFWEFGDGAFSFQKEPQHIYKTKGIYHPRLFATNNYDDGK
                     PPPRRPGTINIKQNANPTKLANATKFFKTDENLALKTNNMPKPDEEMVLILGYKMDFML
                     GSLQGKGKVVLFYNDKEFAKDNFLIDTVRLHHGEKKTENTNFLQMANHYMPSQKYYAQN
                     GPSNDLNAFDLKSKSELIKERVAKYRNMDAWTYDNLGQAEERFMFFSMKTTPEMLADTN
                     AVVTISAMVIPDNPTADVNVYDLELQIVASHDPNKMMLRNRSMNYRFMGKNRRLNYKVR
                     FQNTGKGPAKMVNVGVKIPENLDKSSIKILDTNPKVALRDSSYLTGSVMDTLTNKDSVN
                     FVFRNIYLKGMQQDGVNDADSTKGFVEYSIKFIKKPKKKPFDSGAAIIFDKNEPIYTNQ
                     SKGKFQPGISPGVITGYGMLGSNKNLNDYGDKSYSLGFSISPFSPYRKYLQAEIYLGYY
                     NYSNELKGTTKLDRDTVININDVKSSYLITGREFYQQSNHLNIDLVPLQLRYNLNSFVG
                     IGAGGILSLTINQRTNNYQRSFLVQRNNQTGEVSNFTDQILLAKQNYNFSELATAGFVD
                     VQVGLVRKGPALGFRYIHSFSVKDERLFTYLSWKF"
     misc_feature    6412..6427
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            complement(6527..7567)
                     /locus_tag="B176_RS0111170"
     CDS             complement(6527..7567)
                     /EC_number="5.1.3.-"
                     /GO_function="GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258897.1"
                     /locus_tag="B176_RS0111170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldose epimerase family protein"
                     /protein_id="WP_017258897.1"
                     /transl_table=11
                     /translation="MLENIQKAFQQSIGNKQVALFWLKNEEINVGICNYGARITHFIVS
                     KKNIPVDITLGFNSLEEYISKQNELYYGVTVGRFANRIEDAKFTLNGERYQLDANNGGN
                     SLHSGNIAFHNKVWDVKEVKENSIKLAILSPDGEGGFPGDLTCEVSFTLTDDNELIVNY
                     SAKTDKDTVINLTNHAYFNLNGEESGSILNHEICINADEFLPIKENCIPKGEFEDVANT
                     PFDFREGKTIEQDIHLENEQLKFGNGYDHSFAINQTEIMNFAASAKGDQTSLTLEIYTT
                     EPGMQFYTGNYLAGDKGKRGTSYSERTGFCFETQHHPNSPNQQNFPSTVLKAGEEFKSI
                     TVYKVS"
     gene            7749..9881
                     /gene="rnr"
                     /locus_tag="B176_RS0111175"
     CDS             7749..9881
                     /EC_number="3.1.13.1"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rnr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258898.1"
                     /locus_tag="B176_RS0111175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonuclease R"
                     /protein_id="WP_017258898.1"
                     /transl_table=11
                     /translation="MSNHQGNSIKKILTELISNVLEKSGNKPMNHRQIANKLNIIDPDS
                     KTTILEVLESQTEKGVFLEIGKGKYKLHEVKAFLTGKIAMSNDGSAFVIPDDELEKDIY
                     IAPRKVRTALHGDKVKIHVYESSKGKRKEGEVVEILERVKMEFTGIVKLSQHFAFFIPD
                     DRKMLHDIFIPLEDLNGARNGVKALARIVDWPAGAKNPVGIIKSVLGKQGENNTEMNAI
                     LAEYGFPLAFPDEVEKEAQEISPEITAEEIAKRRDFRKTLTFTIDPFDAKDFDDAISFK
                     TLENGNYEVGVHIADVSHYLIPDSILDKEAYDRGTSVYLVDRVIPMLPEVLSNNLCSLR
                     PKEEKLCFSAVFEMDETANIVGEWFGKTVIYSDHRFAYEEVQEIIENKAGDYAEEILKL
                     NHLAHILRDKKFKHGAISFESTEVKFKLDEHGKPIGVYVKERKDAHKLIEDFMLLANKK
                     VAEFIAKKGKGKHKYTFVYRAHDSPKPDSLVAFAVFASKFGHKISTKSDRDTARSLNKL
                     MADVEGTKEQNVLTQLAIRSMAKAIYTTKSSSHYGLAFDFYTHFTSPIRRYPDIMVHRL
                     LEYYLAGGDSVNADHYEKMCQHASQMEKKAADAERASIKYKQAEYLEDNIGQIYMGIIS
                     GVTEWGMYVEIQENKCEGMIRLRDISDDFYVLDEKNYCIIGQKKKRTYQLGDEVKIKVK
                     RVDLAKRQIDFSLIVE"
     gene            10001..10975
                     /locus_tag="B176_RS0111180"
     CDS             10001..10975
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258899.1"
                     /locus_tag="B176_RS0111180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_017258899.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.4e-68, bitscore:
                     225.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSIKELQQIIDTAVKEIHYPTTPNELYEPIAYLMALGGKRLRPA
                     LVLMATDLFGGDIEDAKAPALAIEMFHNFTLMHDDIMDNAPIRRGQPTVHEKWSNSVAI
                     LSGDVMFVKAYRLMIQVKPEILTAVLEVFNKTAIEVCEGQQIDMNFELRKEVSIEEYLE
                     MIRLKTAVLLGGALKIGALIGDASAQNANLLYQFGENLGLAFQLQDDILDVYGDPEKFG
                     KQVGGDIMSNKKTFLLIKALELAQGDDLINLTAWINKKDFVPEEKVEAVKTLYNRLNIR
                     TLSEEVMQQYAKLALDAFEKIDTPIENKKTLLSFAEMLVEREN"
     gene            complement(11107..11985)
                     /locus_tag="B176_RS0111185"
     CDS             complement(11107..11985)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258900.1"
                     /locus_tag="B176_RS0111185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sterol desaturase family protein"
                     /protein_id="WP_017258900.1"
                     /transl_table=11
                     /translation="MYKYVEIFLGSYSGYWNYLTGEILNPSWHNYFYWLIMLSLGIWLL
                     EIIIPWRKNQSVFRQDFWMDGFYMFFNFFLFSLIAYNAISNIAVEAFTDFLGLFGIKNM
                     VAIQVHELPKWVQLFVLFVVADFIHWNVHRMLHRYSWMWEFHKVHHSVKEMGFAAHLRF
                     HWMESIFYKTAQYIPLAMIGFGLKDFFIVHIFATAIGHLNHSNLNLSYGPFKYVLNNPK
                     MHIWHHVKKLPAGTYGVNYGISLSLWDYIFRTVYMPENGRDIELGFEGDEDFPKKLKDQ
                     LIHPWESKENK"
     gene            complement(12297..15668)
                     /locus_tag="B176_RS0111195"
     CDS             complement(12297..15668)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140658 - ATP-dependent chromatin
                     remodeler activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258902.1"
                     /locus_tag="B176_RS0111195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_017258902.1"
                     /transl_table=11
                     /translation="MPKESHPQTHRFVFEDFSFEDFSEQQVLKYLKSEIIASNLKVHPL
                     NIQINQASFEIGDGKKASPIVTLVKGEKQLLLSCDCGFNHSDQFLCDYQAKAILTICNK
                     PEYRVFFYKKQRNQIFKAEASAYGLENEEDLSIYFELIFEDNSYSVKAKNPQIVPLNSF
                     ALKALKTKLAEVVSPFSPQIQNFDKTKIIVLKQHKYYRHLCIDFYEANLTKDGSVKNPL
                     VPLNPLDFIWNTDRPEEIKFFSALQKFANPVEQQITATELKALRAIVENPNNYCVFQHQ
                     NGKADQISASILTMINLRKANFEIKMEVLQNGDFYHINASVSIGGKQYELSDIHLRYDS
                     FITRGNDFYLVEHPQKLAVISWLKQHPAGMQIHQSKYLNFKRTFLENIEDQVDIHYKYL
                     KIASQAQLKSNGFLAPTEKIIYLSDFGEHVMVIPVMRYGEAEVQVRSRKQVYGLGKGNK
                     EFLVTRDDEKEVDFIALLTKQHAYFAEQLENGLHYFYLHKKHFLNEEWFLNTFEEWQNR
                     DITILGFNELENNALNLNKAKITIKIISGLNWFNVNIKAGFGVKKASLKHLHKAIRNKH
                     KYVKLDDGTLGILPEEWISKFADYFNVGEVIDEETLQIPKINFTTVDELFDAEMLDEKA
                     SEELKYYKKQFVDFDRIGKVEVPKGLQTELRDYQKQGLNWLNFLDEFNFGGILADDMGL
                     GKTVQIIAFILLQQQKSKQNTNLLVLPTSLIFNWQAEFENFAPNLKVLTLYGDQRQKSI
                     DNFGDYQVVITTYGTLLSDVNFLKNYLFNYIFLDESQAIKNPESQRYKAARLLQSRNKV
                     AITGTPIENNTYDLYGQLSFACPGLLGSKRYFKDIYAMPIDMFKDGKKASALHQKVKPF
                     ILRRTKSEVDLQLPEKTEMVIYCEMETEQRRIYEAYEKEFREYISAITNEELRRDSMNV
                     LKGLTRLRQICNSPKLLKGDRLPGDQSVKIDMLISQIKEHSPNHKILVFSQFVGMLDLV
                     KAQLMQENIAFSYLTGQTQNRKSVVEGFQTDESIKVFLVSLKAGGVGLNLTEADYVYLI
                     DPWWNPAVENQAIDRVHRIGQTKKVVAIRLICNNTVEEKMLELQQRKRELFQNVIPSDN
                     EFVSAFSKEELLKIIG"
     gene            complement(17220..18821)
                     /locus_tag="B176_RS0111200"
     CDS             complement(17220..18821)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_process="GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258903.1"
                     /locus_tag="B176_RS0111200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide chain release factor 3"
                     /protein_id="WP_017258903.1"
                     /transl_table=11
                     /translation="MTTLQTEIAKRRTFGIISHPDAGKTTLTEKLLLFGGAIQKAGTVK
                     RNKDEKTATSDFMEIEKQRGISVATSVMGFEYKNAKINILDTPGHKDFAEDTYRTLTAV
                     DSVILVVDCVKGVEEQTKKLMQVCRMRHTPVIIFINKMDREGKDPFDLLEELEKELNIS
                     TRPLSWPIGIGHSFKGVYQLNNKILNLFGANKKSIEKDQISIADLADPQVDQLVGDRLA
                     AKLRDDVELIETVAEPFDRSLYLAGYLAPVFFGSAINNFGVQELLETFIEIAPTPQGRE
                     TDTRKVESSEPKFTGFVFKIHANLDPNHRDRIAFCRICSGTFKRNTFYHHNRLNKKLKF
                     ASPTSFMADSKSLVEEAYPGDVIGLYDSGNFKIGDTLTEGESLQFVGIPSFSPEIFREL
                     ENNDPFKTKQLEKGIHQLSDEGVAQLFIQNPGNRKIVGTVGELQFEVIQFRLLNEYGAA
                     CTFRHMNITKAKWVSATSEEELKKFILRHSSKIAYDKESKPVFLAGSAWDIEYATKQYP
                     EVSFHDTSEWSLMDKK"
     misc_feature    complement(18992..19005)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.48"
                     /tool="antismash"
     gene            19141..20763
                     /locus_tag="B176_RS0111205"
     CDS             19141..20763
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024685.5"
                     /locus_tag="B176_RS0111205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SIR2 family protein"
                     /protein_id="WP_017258904.1"
                     /transl_table=11
                     /translation="MTEIVKSTKQEFKRKLRDILVDSQRPPFLFVGSGISIRYYSIPTW
                     MDLLEAFVEDNRECFDYKFGYYSSKCSNDPLRIASKLAEEFHEYWWKSEKYNLSREKHQ
                     QIAGQDTEIAFKIELSNFVERSIKHSEELLSEIDILSSAVISGILTTNWDDFMQNTFTD
                     FQVEIGQKEAIFADQRAIGELYKIHGCTSKPESLVVTTADYHKFIASNHYLNAKLLTLF
                     AEYPIMFVGYSLSDHNIELIIKNLISCLDKDLFHVEKLKNRLFFVEWQTKPCEPSLEHS
                     TYTMASITIPLIKIKVHDYIDVWEVLSQLPRTLSVKTLRQLQSMVFDFVTTSKPMGKVF
                     VNGIDELDKIENLEVVVGFGNISKLEDKGIIGLKTGDLMEDILFDQISSHNYSEIVEKL
                     LPSVVHQNTFVPFFKYQRGYKNLNKDNSLKQHAGTNFTLSRSASISMDDYRVDSMKTKT
                     MKLVRKYNTLSDLIDDCSEIHAIQRIPYLSQEKIDTNVLLTFLKKNWEELGKKEHPYST
                     HIRKCICILDFLTYAYQEDKNNN"
ORIGIN
        1 aatttcagat atgttttgtt tgagcgccat gtctgagcgt tttccattta ctgtgattcg
       61 aacatagata ggcgctttgc cctctttatc ttttctattc tttctaataa aaaagaacat
      121 tccaaaggta ttttgtggtg tattcataac atttgaagct taaaatgact gattataaag
      181 gaaaaaaatc taaaaccagt caaaattttt taattaaaac tctaattatc agtcatttac
      241 tattccaaaa ctgcaataaa aacaggtagc cgaataggac accgaatgat tattcaagta
      301 gccgtaaaag cacttctgag gcatttttct aggttttcta gttaaaggga taattcctag
      361 gacattttgt tttgaactca tatcatttaa tttgtttata aatgattggt tttgaagttg
      421 ccccttttta ataggacacc ctgtttatat taaacaacca caaaaccaat caaaattaac
      481 tagtaaataa ttgaatatca gatatttaaa atattataag tccaaatata gagaataaaa
      541 ataggacacc gaataggaca cctttacatt ggttttaatt gatatatatt ggtttgataa
      601 aaatgaaaaa accccttaaa tcatacaatt taaggggttt tagtgacttt tcgtagccta
      661 aaagtcggga tggcaggatt cgaacctgcg gcctcctgct cccaaagcag gcgcgatacc
      721 gggctacgct acatcccgat tattcatcgt tgggagtgca aatgtagctt ttttatcatt
      781 agctccaaat ttatttttac aaaaaataag ctttaaatgc ttaatcattt aacatttagc
      841 ttaatcaact gatttttaga atattaattt ccaaaaaatt ctcagcaatt tctgtaaaaa
      901 actaaaccta tcgctttacg ttaaaattga cacgataaat gccagtttaa atcttatttc
      961 tttaattttg gattttagta tcagaacgca actatgaatg tagaattgtt tattccttgc
     1021 tttgttgacc agctttaccc agaaacagca aaaaacacct ataagatttt acaaaaagca
     1081 ggatgtaatg taatttataa tccggaacag acttgttgtg gtcagccggc ttataatgcg
     1141 ggcttttggg acgatgcaaa ggaagttggc agtaaatttc tgaatgattt ttctgaacag
     1201 aattacatcg tttctccatc tgcttcctgt actggaatgg taaaaaattc ttataacgat
     1261 ttattcttta acacctccat ccataacaag tgtagaaata tccaaagcca tatttacgaa
     1321 ctatctgatt ttctaatcaa tgtattaaag aaggattatt ttggggctga gctactggga
     1381 aaagctgttt tccacgattc atgtagtgga ttaagagaat gtaacataaa agaagagcct
     1441 cggaagttgc tttctaaagt tttaggtttg gaagtggtag agatgaaaga cagtgatgtt
     1501 tgttgtggat ttgggggaac tttcgcggtg aaatttgatg gaatttctac cgctatggcc
     1561 gaacaaaagg ttcagaacgc tttagacacg ggcgcagaaa tcatcatttc aactgacaca
     1621 tcttgtttat tacaactaca agcttacatc gataaaaata atattcaaat taaaacgatg
     1681 caccttgcgg atgttttagc cacgggttgg ggaaatgttt aatcgttttt tacgataaaa
     1741 aaacactaca ataccaagta aaatcgataa agaaacacca ctataaacta gaaagtggcc
     1801 aggctcttct atcgtcaccc caaaatcttc accggtataa atcaagctat cccaataata
     1861 gggcaataat accatctgat ttttatgctt ttgtttaagc cattgtaact tggtttttgc
     1921 caacgtacct gctgtggttt ttcgttgtaa caaagttcga taatagttca ccatcaaatc
     1981 tgctcccgat tgatcattta cattccataa gcttgaaatc acaccttttg aacccgcagc
     2041 aataaaacct cgagaaaaac taagtacgcc ctcacccgat agataagcgc catcagcagt
     2101 ttgacaagca cttaatacga ccagttctgg tactttttgt tgactcgcta attccaaaag
     2161 ataaaatcta tcgtggtaca actctaaaac gggttctttt aagctatctg taagatatga
     2221 atgactacta aggtgcaaaa tatcagaatg gttaatagcc tgtttaaaat tatcaacggt
     2281 ggcatcctca tttttaaaaa aatctccttt aataaacctc ttcaacgcat catattcggc
     2341 aaccaccgct gggatttcat tttttgagga ccctgttcgc gataaaaata tgcctgtaaa
     2401 ttggtatctg taagctgttt tagatcgctt tactgacggg atagaactta gcgagaaacc
     2461 ataacttatt tcaactttct taattaaaaa aggccattgt gctacgtttt tagccacacc
     2521 agattcagta atcagacttt caaaaggtag aaaattcaaa attccatctt ttataagtaa
     2581 tactttttgg ttattgatat tgacttggga aaatagtagc ttttggatat tatttgacgc
     2641 attataaaaa gcttgaggat tgttaatcat ttctgcaggg ccattataaa agtacttctc
     2701 taagtaatga ccaaccgagg ctgaaagctg tttagtagtt ccaagtttaa taacctgact
     2761 cactttatga tggttcgcaa taatcatata gctatttcta tctccacaga aaaaaataat
     2821 tgcttgcttt tctaccggta ttttttgcag tatttgcgtg gctttaagcg ttaaactagg
     2881 gtttttctga ttcaattgtt tctgtaggct ggaaagctga aactctagat cggctatttt
     2941 ttttaagata acagtatttg aattgctttg cttttgtttt tgatagtacg acaaaagctg
     3001 ttggatttta atcttttgct gttgtagcgg atttttcttt cttttagaat cgcttgactg
     3061 acttgcattg agttcatcaa acaaaattcg ggactttgtt tgctcagaaa acatgaggat
     3121 atggttagca tacacagcat ccttagtctt aacccataac tcatacgatt tctcaataac
     3181 cagttctgcc aaagctttgg actctgcttg aagtcgctcc tttgaaacat catatgtgta
     3241 ttctttcctc agctcttcgg caacggcaaa agctaaaata gatgcctgta acgactgctt
     3301 tttatcacct aaacgcgcta acacttcggc tttacccatt aaagcagcct gtagcttatt
     3361 ttcgccgaaa agcgtacgct catctggcaa atcgttgggt tttaataatt taaactctgg
     3421 caataagtaa atcaaggctt gattatactg tgaaagtgct tgctgatagt ctttttggac
     3481 taaataaacg cttcctaatt ggttaatgag ataagtaagt tccctttttc gcccaccacc
     3541 caaaagcgag tatattaatt tttgtgcatt tttataaaaa tttttggccg attctaaatt
     3601 ctcttgattg agctgaatat ctccagcgag cgtataagcg ctcagcaacc aatatgcggt
     3661 ggagctattt aatttctgga gttttaaatg cctaatcgcg gtagaaacaa aaccttcggc
     3721 cttagcgtaa tctttattct cattgctgat atcggccatg ttagataaca gcaaaccgta
     3781 gatcgcactt tttttatcag ctattttcaa acccgctaat gctgattgct ctgcatttct
     3841 caagtcgttt tttgagcgat aggaagtaga taaattacaa taggctgagg ttgcgaggtc
     3901 taacttgttt tgctttagag ccagattcaa actccgtttt tggatgtaaa tcgctcgctc
     3961 ataatcgccc aaacgggtgt aattgttaga tagtggcttt aaaatgtatt cttcgatatc
     4021 taaaccagtt ggatgttttt ccgagaattc ataagcgttc tcgtaacaag taatagacgc
     4081 cagtatatca ccgttttgaa gttgatagta accttggtta accagtaaaa acaaccacga
     4141 ttcattttct tgttgagttt ttggtgctct ccaagctaac ttattggttt gcattagaaa
     4201 caacaatcgt tctgacggtt gaattaaagc aaaatcgacc ctgctatcta tccattttgc
     4261 taaactatcc tcggtcttaa atacactgag tttcttttga aatacagcat cagtattttg
     4321 tccaaaagtt gtggaaaaag ttataaaaat acagaagatg aatattgaaa ttctcgccaa
     4381 aaccaggtaa atatttagct aaaagtagct aaaatttcca gcttaggtaa gtaaaaagtc
     4441 tttcgtcctt taccgaaaac gaatggatat acctaaaacc taaagccgga cctttacgta
     4501 ccaagccaac ttgcacatct acgaaacctg cagttgcaag ctccgaaaaa ttatagtttt
     4561 gtttagctaa tagaatttga tcggtaaaat tactgacctc tcctgtctga ttgttacgtt
     4621 gcaccagaaa tgaccgttga tagttgttag tgcgctgatt aatagttaaa gaaagaattc
     4681 ctcccgcccc tattccgaca aaagaattaa gattgtatcg caactgcaga ggcaccaaat
     4741 ctatatttaa atggttggat tgctggtaaa actctctacc agtaattaaa taactgcttt
     4801 ttacatcatt tatattaatt acagtatctc tgtcgagttt tgtagtgccc ttaagctcat
     4861 tagaataatt ataataccct aaataaattt ctgcttgtag gtattttctg tacggagaaa
     4921 atggtgaaat actaaagccc aacgaatagc ttttatcgcc ataatcgttc aaatttttat
     4981 tgctacccaa cattccgtag cccgtgatta cacccggtga aatgccaggt tggaatttcc
     5041 cttttgattg attggtgtaa ataggctcgt tcttatcaaa aattattgcg gcgccactat
     5101 caaaaggctt tttctttggt tttttaataa atttgatact gtattccaca aagcctttgg
     5161 tagagtcggc atcgtttaca ccgtcttgtt gcattccttt gaggtaaata tttctgaaga
     5221 caaaattcac gctatcctta tttgttaagg tatccataac agagccagtt aggtagctgg
     5281 aatctcgtaa cgcaacttta gggttggtat ctaaaatttt aatcgatgat ttatctaagt
     5341 tctctggaat ctttacgcca acattcacca ttttagctgg accttttccc gtattttgga
     5401 agcggacttt atagtttaac cgtctatttt tgcccatgaa acggtaattc atggaacggt
     5461 tgcgcaacat cattttattt ggatcatgag aggctacaat ctgtaattcc aaatcgtaaa
     5521 cgtttacgtc tgccgttggg ttatctggaa taaccatggc agaaatagta accaccgcgt
     5581 tcgtatctgc tagcatttcg ggcgtagttt tcatgctaaa aaacataaaa cgttcttccg
     5641 cttgtccaag gttatcgtaa gtccaagcgt ccatattgcg gtacttagca acacgctctt
     5701 ttatcaattc cgatttactt ttcaaatcga atgcattcaa atcattagat ggtccgtttt
     5761 gcgcataata tttttggcta ggcatataat ggtttgccat ctgtagaaaa ttcgtgtttt
     5821 ctgttttctt ttcaccgtga tgcaacctta cggtatctat caaaaaatta tccttggcaa
     5881 attccttatc gttgtaaaac aaaaccactt tccctttgcc ttgtaaactg ccaagcataa
     5941 aatccatttt atagcctaaa atcaacacca tttcctcgtc gggctttggc atattattgg
     6001 tctttaaggc taaattttcg tcggttttga aaaattttgt tgcattagcc aatttggttg
     6061 gattggcgtt ttgcttaata ttgatggttc ctgggcgacg tggcggtggt tttccatcat
     6121 cgtagttgtt agttgcaaat aaacgtgggt ggtaaatccc ttttgtttta taaatatgct
     6181 ggggctcttt ttgaaaagag aatgctccat ctccaaactc ccaaaaatac gtgtaaaatg
     6241 gttctggcgc cccagcgatt ggtctaagcg ggcgtagttc tgatgtgaat ctcacagaat
     6301 cgcctttgaa tgcataatta attttaactg gaattgtatc cgtaggatga acctgggcat
     6361 tcgctttatc cacagcaaaa ccaaaaaaga atatgattat ataaaccaga aatttacgca
     6421 tgtaaataaa tttataaaat ttaaatgaca acaaggtatc taatacttat aaagtaagcc
     6481 tatgatttgt tacctgtctt ccaaaagaaa gttataaaaa acttgattag cttactttat
     6541 aaactgttat cgatttaaat tcctctccag ctttcaacac cgttgaaggg aagttttgtt
     6601 gatttggaga gtttgggtga tgttgtgttt caaagcaaaa gcccgttctt tcgctgtaag
     6661 aagtgcccct ttttccttta tcaccagcta aatagttgcc ggtataaaac tgcatcccgg
     6721 gttctgtggt ataaatttca agcgttaaac ttgtttgatc tccctttgcg gaagcggcaa
     6781 aattcataat ctctgtttga ttaatggcaa aagaatggtc gtagccgtta ccgaacttta
     6841 actgttcatt ttccaaatga atatcctgtt ctattgtttt accttcccta aaatcaaagg
     6901 gtgtatttgc tacatcttca aactcgcctt ttgggataca attttcctta atgggcaaaa
     6961 actcatccgc attaatgcaa atctcgtggt ttaaaattga cccgctttct tccccattca
     7021 aattgaagta agcgtgattt gttaggttaa taacggtatc cttatccgtt ttagcgctat
     7081 aattaacaat cagttcgtta tcatctgtaa gcgtaaagct cacctcgcag gttaaatccc
     7141 caggaaaacc tccttcccca tccggactta atattgccag ttttatgcta ttctctttca
     7201 cttcttttac gtcccaaact ttgttgtgaa aagcgatgtt tccactgtgc aaactgttac
     7261 cgccattgtt ggcatctaac tgatatcttt caccgtttaa tgtaaatttc gcgtcttcta
     7321 tacggtttgc aaatcgacca acggtaactc cgtaataaag ttcgttctgc ttggaaatat
     7381 attcttctaa tgaattaaag ccgagcgtaa tgtcaacagg tatgtttttt tttgaaacaa
     7441 taaagtgcgt tattcttgct ccataattac atattccaac atttatctcc tcatttttta
     7501 accaaaataa tgcaacctgc ttattaccga tactctgttg aaatgctttc tgtatattct
     7561 ctaacatagg ttttgtaaat tgatatcgct aaaataaaaa attggatcag ttttagaaga
     7621 ttaaaacttt tttacaggta aaacttaaga aaaaataaat gttaaacgaa tattaaaaga
     7681 tttataaaag ctaaaaatta aaacataatc tctattttga gctttaaaat aagataacaa
     7741 ttatctcaat gtcaaatcac caaggaaatt ccataaaaaa gattttaacc gagttaatct
     7801 caaacgtact ggaaaaatcg ggcaacaagc ctatgaacca ccgccaaata gcaaataagt
     7861 taaatattat agatccagat tctaagacca caattttaga agttttggaa agccaaaccg
     7921 aaaaaggcgt ttttttagaa ataggcaaag ggaagtataa actacacgag gtaaaagcgt
     7981 ttttaacagg aaaaatagcg atgtcaaacg atggttcggc atttgtaatt ccggacgatg
     8041 agcttgaaaa agatatttac atagcaccaa gaaaggtgag aacagcctta cacggcgata
     8101 aagtaaaaat ccacgtttac gaaagtagta agggaaaacg taaggaaggc gaggtagtgg
     8161 aaattttgga acgcgttaaa atggagttta ccggcatcgt taaactgagt cagcattttg
     8221 ctttttttat ccccgatgac cgtaaaatgt tgcatgatat ttttatcccg ttggaggatt
     8281 tgaatggtgc aagaaacggc gtaaaagctt tagcaagaat tgtagattgg ccagcaggcg
     8341 ctaaaaaccc tgtaggaatt atcaagagtg ttttaggaaa acaaggcgag aacaacaccg
     8401 aaatgaacgc tattttagca gaatacggtt ttccattagc ttttccagac gaagttgaaa
     8461 aagaggctca ggaaatttcg cccgagatta cagcagaaga aattgctaaa cgacgtgatt
     8521 ttagaaaaac cttaactttt accatcgatc cgtttgatgc caaagatttt gatgatgcca
     8581 tttcttttaa aactttagaa aacgggaatt acgaagttgg tgtgcacatt gcagatgttt
     8641 cgcattattt gattccggac agtattttgg ataaggaagc ttatgaccgt ggaacttcgg
     8701 tttacctggt tgatcgagtg atcccgatgt tgcctgaagt tttatcaaat aatttatgtt
     8761 cgttacgccc taaagaagaa aaactgtgct tttctgcagt ttttgagatg gacgagaccg
     8821 caaatattgt tggcgagtgg ttcggtaaaa ccgtgatata tagcgaccac agattcgctt
     8881 atgaagaagt tcaggaaatt atcgagaata aagccggtga ctatgccgaa gaaattttaa
     8941 aactgaacca tttagcacat attttaagag ataagaaatt taaacatggc gccattagtt
     9001 ttgagtcaac agaagttaag tttaagcttg atgaacatgg aaaacctatc ggagtttatg
     9061 taaaagaacg taaagatgcg cacaaactga ttgaggattt tatgcttttg gcaaataaga
     9121 aagtcgcgga gtttattgct aaaaaaggaa aaggaaaaca taaatatacg tttgtttacc
     9181 gggcgcatga ttcgccaaag ccagatagct tagttgcttt tgcagtgttt gcctcgaaat
     9241 tcgggcataa aatctccact aagtctgata gagacaccgc aagaagcctg aataaattaa
     9301 tggctgatgt ggaagggaca aaagagcaga acgtgttaac gcagttggct atacgttcca
     9361 tggcgaaggc catttatact acaaaaagca gtagtcatta tggcttggcg tttgattttt
     9421 acacccactt cacctctcct atccgtcgtt atcccgacat tatggttcac cgattgttag
     9481 agtattattt agccggtggc gatagtgtaa atgcagatca ttatgaaaaa atgtgccagc
     9541 atgcctcgca gatggagaaa aaagccgctg atgcagaacg agcttctatc aaatacaaac
     9601 aagctgaata cttggaagat aatatcggac aaatttacat gggtattatt tctggcgtta
     9661 ccgaatgggg aatgtatgta gaaatccagg aaaacaaatg cgagggtatg attaggctac
     9721 gtgacatttc tgatgatttt tacgttttag acgagaagaa ttattgcatc attgggcaaa
     9781 agaaaaagcg cacttaccaa cttggcgacg aggtcaaaat taaagtgaaa cgtgttgatt
     9841 tagcgaaaag acagatagac tttagtttga ttgtggagta gagatacttg tttgagagta
     9901 aggaataacg aacaaagagt aaagatgaga gctaacctcc atgtttttta aggaaaataa
     9961 aacactattt tcgcaccaat acgcacacat caaaatcgta atgcatagca tcaaagaatt
    10021 acaacaaatt atagacacag cagttaagga aatacattat ccaacaacgc caaacgaatt
    10081 atacgaacct attgcctatt taatggcttt aggtggaaaa cggttaaggc ctgctttggt
    10141 tttgatggct actgatttat tcgggggaga tattgaagat gcaaaggctc cggctttggc
    10201 cattgaaatg ttccacaatt tcaccttgat gcatgacgat attatggaca atgcaccgat
    10261 tcgtcgcgga cagccaactg ttcacgaaaa gtggagcaat tctgttgcta ttctatcggg
    10321 cgatgtgatg tttgtaaaag cttatcggct gatgattcag gttaaacctg agattttgac
    10381 tgccgtttta gaagttttca ataaaacagc aatagaagtt tgcgaaggtc agcagattga
    10441 tatgaacttt gaattacgca aagaagtatc gattgaagaa tacttggaaa tgatccgctt
    10501 aaaaactgcg gttttattgg gtggtgcgtt aaaaatcggt gctttaattg gcgatgcttc
    10561 tgcacaaaat gccaacttac tttaccagtt tggcgaaaac ttaggtttgg cctttcagct
    10621 ccaggatgat attttggacg tttatggaga tccagaaaag tttggaaaac aggtgggtgg
    10681 cgatatcatg tcaaacaaaa aaaccttttt actgattaaa gctttagaac tggcccaagg
    10741 cgatgacctg ataaatttaa ccgcttggat caataaaaaa gattttgttc cagaagaaaa
    10801 agtggaagcg gttaaaacgt tgtacaaccg tttaaatatc cgaaccttgt ctgaagaagt
    10861 gatgcaacaa tacgcaaaac tagctttaga tgcatttgag aaaattgata ctcctataga
    10921 aaataaaaaa acacttttga gctttgcgga gatgttagtt gagcgggaaa attaattttg
    10981 aataaatgaa ggatagaatg agtgaatgct cgggctattt tgaatgagag aagaagggaa
    11041 tggctttgta attttgtagg agcgaatgat tgagcgcctc acaattttga acggagaatg
    11101 aaaacgctat ttattttctt ttgattccca aggatgaatt agttggtctt tcaatttttt
    11161 cgggaaatct tcgtcgcctt caaacccgag ctcaatatct cttccgttct cgggcatata
    11221 aacggttctg aagatataat cccacaggct caaacttatt ccataattaa cgccataagt
    11281 gcctgccggt aatttcttca cgtgatgcca gatgtgcatc ttagggttgt ttaaaacata
    11341 tttaaacggg ccatatgaaa gatttaggtt agaatggttc aaatgtccaa tagccgtagc
    11401 gaaaatatgg acgataaaaa aatctttaag accaaaacca atcatcgcta aaggaatata
    11461 ttgcgctgtt ttatagaaaa tcgattccat ccaatgaaag cgtaaatgtg cagcaaatcc
    11521 catttccttt acagagtgat ggactttatg aaattcccac atccaagaat atctgtgcaa
    11581 cattctgtgg acattccaat ggataaaatc agcgacgaca aaaagaacaa atagctgtac
    11641 ccactttgga agctcgtgaa cttgtatagc caccatgttc tttattccaa ataatcctaa
    11701 aaaatcagta aaagcctcaa cagcaatgtt tgagatggcg ttataggcaa ttaacgagaa
    11761 taggaaaaaa ttaaaaaaca tgtaaaaacc gtccatccaa aaatcctgac ggaaaactga
    11821 ttggttttta cgccaaggga taatgatttc taaaagccaa atccccagag aaagcatgat
    11881 caaccagtaa aaatagttat gccagctcgg gtttaaaatc tctccagtta ggtagttcca
    11941 ataaccagaa tatgacccta aaaatatctc aacgtattta tacatggtta ttagcaaata
    12001 acaaactaag ttttggtttt agctttcgga ttcacagcac aagtattatt tacctaaaca
    12061 attgaggtta aatattgatt gatacaaaaa gaaaccagct aacaaaagta gcacatattg
    12121 ttgatttgca atagctccaa atccaagagt gacagccatc agaaatttga tggttcgcat
    12181 aaaattccaa ctatgaagat gtttgtggta agtatttagg atgttttgca tttgaacaac
    12241 ctacgcaaat taagactggc agcagtcatt ttatcgttaa attcaactgt gctttttcag
    12301 ccaataatct tcaacagctc ttctttcgaa aacgcactaa caaattcgtt atcagaagga
    12361 atcacattct ggaaaagttc cctctttctt tgttgcaatt ctagcatttt ttcttctacg
    12421 gtattgttgc agattaagcg aatggcaact acttttttgg tttgcccgat acgatgcacc
    12481 cgatctatcg cctgattctc aaccgccgga ttccaccaag ggtcaatcaa ataaacataa
    12541 tctgcttccg ttaaatttag gccaacacca cctgctttta agcttaccaa aaacacttta
    12601 atgctttcat cagtttgaaa cccctccact accgattttc tgttttgcgt ttgcccggtt
    12661 aaatagctga aagcaatatt ttcctgcatt agttgagctt tgaccaaatc caacatccca
    12721 acaaattggg agaaaactaa aattttgtga ttcggcgagt gctctttaat ttgtgaaatc
    12781 aacatatcga ttttcacgga ctgatctccc ggtaaacggt cgcctttcaa cagttttgga
    12841 gaattgcaaa tctgccttaa tcgagttaaa ccttttaaaa cattcatgct gtctcttcgc
    12901 aattcttcat tggttattgc cgaaatatat tcgcggaact ctttttcata agcttcgtaa
    12961 attcgtcgct gttcggtttc catttcgcaa taaattacca tttccgtctt ttccggaagt
    13021 tgcaaatcca cttcgctttt ggtacgtctt aatataaacg gctttacttt ttggtgcaat
    13081 gccgaagcct ttttaccgtc tttaaacata tcaatcggca tggcgtagat atctttaaag
    13141 taacgtttac tgcctaataa acccggacaa gcaaaagaaa gctgaccgta taaatcgtaa
    13201 gtattatttt ctatcggtgt tccggtgatg gctactttat ttctggattg tagcaatctc
    13261 gccgctttat acctttgcga ttcgggattt ttaatcgcct gtgattcatc taaaaagata
    13321 tagttgaata gatagttttt tagaaaattg acatcggaca aaagcgttcc atacgtagta
    13381 atcaccacct gatagtcacc aaaattatca atgctttttt gtctttgatc tccgtaaagc
    13441 gtaaggactt tcaaattggg cgcaaaattt tcaaactcgg cctgccagtt aaaaataagc
    13501 gatgttggca acacgagcaa gttggtgttt tgctttgatt tttgttgttg caacaggata
    13561 aacgcgataa tctggacggt tttacccaaa cccatgtcat ccgctaaaat cccaccaaaa
    13621 ttaaattcat ccaaaaaatt gagccagttt aaaccttgtt tttggtaatc acgcagttca
    13681 gtttgcaatc cttttggcac ttccactttg cctattcgat caaaatctac aaactgcttt
    13741 ttgtaatatt taagttcttc gctggctttc tcatccagca tctccgcatc aaacaattca
    13801 tcaacagtag taaaattaat ctttgggatt tgtaacgttt cctcatcaat cacctcgcca
    13861 acattaaaat agtcagcaaa cttacttatc cactcctcag gtaaaatccc caaagttcca
    13921 tcatctagtt tcacgtattt gtgtttattt ctgatggctt tgtgcagatg ctttaaactt
    13981 gctttcttta cgccaaagcc agcttttatg ttgacattaa accagtttaa accactgata
    14041 attttaatgg ttattttagc tttatttaag tttaaagcat tgttttccaa ttcattaaat
    14101 cctaaaattg taatatcacg attttgccat tcttcaaacg tatttaaaaa ccattcttca
    14161 tttaaaaaat gctttttgtg taagtaaaaa taatgcaggc cattttccaa ctgctcggca
    14221 aaataagcgt gttgcttggt gagcaaagcg ataaagtcaa cttctttttc atcgtcccga
    14281 gtcaccaaaa actctttgtt tcctttacct aaaccataga cctgttttct gctccgcacc
    14341 tgcacttccg cttctccata gcgcatcacg gggataacca ttacgtgttc accaaaatca
    14401 gacaggtaaa taatcttctc tgttggcgct aaaaacccgt tgcttttgag ctgcgcttgc
    14461 gacgctattt ttaggtattt ataatggata tcaacttggt cttctatatt ctccaaaaac
    14521 gtccttttaa aattgaggta cttagattga tgaatctgca tcccggctgg atgctgtttt
    14581 aaccaagaga taaccgccaa tttttgtgga tgttccacca agtaaaaatc gtttccacgt
    14641 gtaataaaac tatcgtagcg taggtgaata tcacttaatt cgtattgctt tccgccgatt
    14701 gaaacactag cattgatgtg atagaaatcg ccgttttgta aaacctccat cttaatttca
    14761 aagttggctt tacgcaaatt tatcatggtt aaaatacttg cacttatttg gtcagcttta
    14821 ccattctgat gttgaaaaac acaataattg tttgggtttt caacaattgc tcttaaggct
    14881 ttcaattcgg ttgcggtgat ttgttgctca accggatttg caaacttctg taaagccgaa
    14941 aaaaacttaa tctcttcagg tcggtcggtg ttccagataa aatctaaagg atttagggga
    15001 acgagtggat ttttgacact tccatccttg gtcaaattgg cttcgtaaaa atcgatacat
    15061 aagtgacggt aatatttatg ctgttttaaa acgatgattt ttgttttatc aaagttttgg
    15121 atttggggag aaaaaggaga gacgacttcc gcaagttttg ttttcaaagc ttttaaagca
    15181 aatgaattta gcggaacaat ttgtggattt ttcgctttaa cggaatagct attgtcttca
    15241 aaaatcagct caaaataaat ggataaatct tcttcgtttt ccaatccgta agctgaagct
    15301 tctgctttaa aaatttggtt gcgctgtttt ttataaaaga aaactcggta ctctggttta
    15361 ttgcagatgg ttaaaattgc ctttgcttgg taatcacaca aaaactgatc ggaatgatta
    15421 aaaccgcaat cacagcttaa taacaattgc ttctcacctt ttaccaaggt tacaatcgga
    15481 cttgcttttt taccatcccc tatctcgaac gaagcttgat ttatttggat atttaaggga
    15541 tgaactttta aattggaggc tattatttca gattttaaat actttaaaac ctgttgctca
    15601 gagaaatcct caaaactaaa atcttcgaat acgaaacggt gggtttgagg atgggattct
    15661 ttgggcatta attgtttttt tctttcgggg caatttagta aaatcttcct ttgttaccgc
    15721 gtcatggcga agcgaagcgc cggaatgcgt aagggtgctg tggcaatccc cgcgtttttt
    15781 tatgcactaa cttatgtcca agcatggtct ttcgcagaag acccctgcgt ttgtttttaa
    15841 tttattcttt taagaaattt cttattaact atcataatct ccccggctca ttgccgccgg
    15901 aaagctagtg actttttttt ccgcaaaaaa agtaaccaaa aaaactctcg cctgcgccct
    15961 ttgctacaaa ggaagtgctt ttagttcttc atcaatatcg caaagaccaa gggcgaactt
    16021 atcggttatg aaagggttgt gcttttaaga gctcgttatt ttaaaatctt cgagtccaag
    16081 cagggtttct cttttcgaga accctgcgtt tgcttttact gcgtcattgc gaagcaaagc
    16141 tgtcggctgt gtatgggcgc tgtggcaatc cccgcgtttt ttttgcacta acttttgtct
    16201 ttttttaatt aaagtagaat tttgttttga aatctccccg gctcattgcc gccggaaagg
    16261 ctagtaactt ttttttccgc aaaaaagtaa ccaaaaaaac tctcgcctgc gccctttgct
    16321 acaaaggaag tgcttttagt tcttcatcaa tatcgcaaag accaagggcg aacttatcgg
    16381 ttatgaaagg gttgtgcttt taagagctcg ttattttaaa atcttcgagt ccaagcaggg
    16441 tttctctttt cgagaaccct gcgtttgctt ttactgcgtc attgcgaagc aaagctgtcg
    16501 gctgtgtatg ggcgctgtgg caatccccgc gttttttttg cactaacttt tgtctttttt
    16561 taattaaagt agaattttgt tttgaaatct ccccggctca ttgccgccgg aaaggctagt
    16621 aacttttttt tccgcaaaaa agtaaccaaa aaaactctcg cctgcgccct ttgctacaaa
    16681 ggaagtgctt ttagttcttc atcaataccg caaagaccaa gggcgaactt atcggttatg
    16741 aatggtagtg cttttattct aaactatttt tcaaaattat tcttgtattg gattagcaga
    16801 gccactatga aatccggcat ctgaatattt ggattggagc cgaataaatc ttttgtagtt
    16861 cctttgttaa accacaggcg tcagcaatcc gcagaaatgg tgtagaaaat ttgttaaacc
    16921 actgccgttc ccacgacttg gattgcgctc aaagatttat tgaggtggaa tgaacaaaga
    16981 ttctgaagcc ttgattttat tcaattaatt tattgttttt ataggctttc atgtgttcgc
    17041 tccgctcggg ttttggttct tttttcatca aggaaaaaag aacttgagct tgtcccgctc
    17101 aagagggacg gaaagcatgt gtggaagcct aaacgcagta tatccaccca gcgaaacaaa
    17161 caaacaaaca aacaaacaaa caaacaaaca aacaaacaaa caaacaaaca aaccaaatct
    17221 tacttcttat ccatcaaact ccattcagaa gtatcatgga aactaacttc aggatactgc
    17281 ttggtagcat actcaatatc ccaagcagaa cctgctaaaa acaccggttt actttcttta
    17341 tcgtaagcta tttttgaact atgtcttaaa ataaatttct tcaattcctc ttcagaagtc
    17401 gcggaaaccc attttgcctt cgtgatgttc atgtggcgga aagtacaggc agcgccatat
    17461 tcgttcaata atctgaactg aataacctca aactgcaact ctccgactgt accaacaatc
    17521 ttgcggtttc ccggattttg gataaacagc tgcgcaacac cttcatcact caactggtga
    17581 attccttttt ccagttgttt ggttttaaaa ggatcattat tttctaattc tctgaaaatt
    17641 tctggcgaaa aactcggaat acccacaaac tgcaagcttt ctccctctgt taaagtatcg
    17701 ccaattttaa agtttccaga atcatataaa ccaattacat cacccgggta agcttcttca
    17761 actaaacttt tactgtcagc cataaaactg gttggcgaag caaattttag ctttttgttc
    17821 aatctgttat gatgataaaa agtgtttcgt ttgaacgttc cagagcaaat ccggcaaaaa
    17881 gcaattctat cacgatggtt tgggtctaaa ttggcgtgaa ttttaaacac aaatccggta
    17941 aacttaggtt cagaactttc tacttttctg gtgtctgttt cgcgaccttg aggagttggc
    18001 gcaatttcaa taaaggtttc caacaattcc tgaacaccaa aattattaat ggcacttcca
    18061 aaaaataccg gagctaaata acctgctaag tataaacttc tgtcaaacgg ttctgcaacg
    18121 gtttcaatca actccacatc atctctcaat ttagcagcaa gtctatcacc caccaattga
    18181 tcaacctgcg gatctgctaa atctgcaatg ctgatttggt ctttttctat cgattttttg
    18241 ttggcaccga aaagatttaa aattttgttg tttaactgat aaacaccttt gaatgaatgt
    18301 ccgataccga ttggccaact taacgggcgg gtagaaatat tgagttcttt ttctaattct
    18361 tccaacagat cgaaagggtc tttaccttca cggtccattt tattgatgaa aataataacc
    18421 ggcgtatggc gcattctaca aacctgcatc agttttttag tttgttcctc tacccctttt
    18481 acgcaatcca ccactaaaat aaccgaatcg acagccgtta atgtacggta agtatcttcc
    18541 gcgaaatcct tgtgacccgg cgtatccaaa atattgattt tggcattttt atattcgaaa
    18601 cccattacag aagtcgccac ggaaattcca cgttgctttt caatctccat aaaatcggag
    18661 gttgccgttt tttcgtcttt atttcgctta accgttcccg ctttttggat agcaccacca
    18721 aacaaaagca acttctctgt taaagtagtt tttcctgcat cggggtgact aataattcca
    18781 aaagtacgtc tcttggctat ttctgtttgt aatgttgtca taatttgaag agccgttttt
    18841 gtttcttgct taatgaaatg taacggtttt taattttaaa cggtttgttt aaaatttgcg
    18901 caaatataag agaaaaaatt ggagggatga gatttggatt tctggggcag ttactaattt
    18961 attctaaagt attttttcgg aaactaaaag aaaaacgagc gtttcataac gtaaaaatta
    19021 aatatattgc aaaataattg atttagaatc tccttaaatt tgaattactt tcaaaagatt
    19081 ttgctgatat gattttctaa gttaagtttt ctctaacctt tattaataat taaaattcta
    19141 atgacagaaa ttgtaaagtc tacaaaacaa gaattcaaga gaaaacttag agatatttta
    19201 gttgattcac aacgacctcc atttttattt gttggatcag gtatatcaat tagatattat
    19261 tcaatcccaa catggatgga cttactggag gcatttgttg aagataaccg ggaatgtttt
    19321 gattataagt ttggttatta ttcatcaaag tgttctaatg acccgctacg aattgcgtcg
    19381 aagttagcag aagagtttca tgaatattgg tggaaatcag aaaaatacaa tcttagtcgc
    19441 gaaaagcatc agcaaattgc tggacaagat actgaaatag cttttaaaat tgagctatca
    19501 aattttgtcg aaaggtcgat aaaacatagt gaagaattgc taagtgaaat tgatattctc
    19561 tcgtcagcgg ttatcagtgg tattttgaca acaaattggg atgatttcat gcaaaacacc
    19621 tttacggatt ttcaagttga aatcgggcaa aaggaagcta tttttgctga ccaaagagca
    19681 attggcgaac tttataaaat ccacggatgt acatcaaagc cagaatcgct tgttgtaaca
    19741 actgcagatt accataagtt tattgcaagc aatcactatc tcaacgcaaa gcttttgacc
    19801 ctctttgcag aatacccaat tatgtttgta ggttattccc tctcggacca taatatagag
    19861 ttgattataa aaaatttgat ttcgtgtttg gataaggatt tatttcatgt tgagaaacta
    19921 aaaaacagat tgttctttgt tgaatggcaa acaaaaccat gtgaaccatc attagaacac
    19981 tctacctata caatggcttc aatcacaatt cctttaataa aaattaaggt tcatgattat
    20041 atagatgttt gggaagtttt atcccagcta cctagaacac tttccgtaaa gacactacgt
    20101 caattacaaa gcatggtttt cgattttgta acaacttcaa aacctatggg aaaagttttt
    20161 gtcaacggaa ttgacgaatt agataaaatc gagaatttag aagttgttgt tgggtttggt
    20221 aatatttcga aactcgaaga taagggaatt attggtttaa aaactggtga tttgatggaa
    20281 gatattctat tcgaccaaat ttcttcacac aattattcgg aaattgttga aaaattatta
    20341 ccatcggtag tgcatcaaaa caccttcgta ccgtttttta aatatcagcg tggatataag
    20401 aacttaaata aagacaattc tttaaaacaa catgctggta caaatttcac attatctagg
    20461 tccgcctcga tatcgatgga tgattatcga gtagattcga tgaaaacaaa aactatgaag
    20521 ctagtgagaa aatataatac tttatccgat cttattgatg actgctctga aatacacgcg
    20581 atacaacgta taccgtattt gagtcaagaa aaaatcgata caaatgtctt actaactttt
    20641 ttgaaaaaaa actgggagga gctcggaaaa aaagagcacc catattcaac acatattaga
    20701 aagtgcattt gcatacttga ttttttaact tatgcttatc aagaagataa aaataacaac
    20761 taaaaatatt tctcaaactg gtttaagtgt tcgctttgtc agcgacctct taaatccaaa
    20821 tatttagtag aggactgtgt caggtataaa aaatagactt ttcaaatcat cgatagaaca
    20881 atattatcag tctagaaatt tgctttggaa aaccggacat agtcctctcc atcctaaaag
    20941 catttcagcg accctgaaga aggaacattg aaatg
//
