LOCUS       NZ_JH947126            25771 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Pedobacter arcticus A12 Scaffold2, whole genome shotgun sequence.
ACCESSION   NZ_JH947126
VERSION     NZ_JH947126.1
KEYWORDS    WGS; RefSeq.
SOURCE      Pedobacter arcticus A12
  ORGANISM  Pedobacter arcticus A12
            Bacteria; Pseudomonadati; Bacteroidota; Sphingobacteriia;
            Sphingobacteriales; Sphingobacteriaceae; Pedobacter.
REFERENCE   1  (bases 1 to 1024955)
  AUTHORS   Yin,Y., Yue,G., Gao,Q., Wang,Z., Peng,F., Fang,C., Yang,X. and
            Pan,L.
  TITLE     Genome sequence of Pedobacter arcticus sp. nov., a sea ice bacterium
            isolated from tundra soil
  JOURNAL   J Bacteriol 194 (23), 6688 (2012)
   PUBMED   23144423
REFERENCE   2  (bases 1 to 1024955)
  AUTHORS   Ye,Y., Peng,F., Xu,Y. and Chengxiang,F.
  TITLE     Genome sequence of Pedobacter arcticus A12, a sea-ice bacterium
            isolated from the tundra soil
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 1024955)
  AUTHORS   Ye,Y., Peng,F., Xu,Y. and Chengxiang,F.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2012) China Center for Type Culture Collection
            (CCTCC), College of Life Sciences, Wuhan University, 16 Luojiashan
            Road, Wuhan, Hubei 430072, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. May-2012
            Genome Coverage                   :: 253x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000302595.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 09:54:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,583
            CDSs (total)                      :: 3,537
            Genes (coding)                    :: 3,512
            CDSs (with protein)               :: 3,512
            Genes (RNA)                       :: 46
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 40
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 25
            CDSs (without protein)            :: 25
            Pseudo Genes (ambiguous residues) :: 0 of 25
            Pseudo Genes (frameshifted)       :: 6 of 25
            Pseudo Genes (incomplete)         :: 18 of 25
            Pseudo Genes (internal stop)      :: 4 of 25
            Pseudo Genes (multiple problems)  :: 2 of 25
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:05:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 199045
            Orig. end                         :: 224816
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JH947126.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25771
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25771
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22558
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22558
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12558](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12558
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(697..712)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            731..2053
                     /locus_tag="B176_RS0107730"
     CDS             731..2053
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258225.1"
                     /locus_tag="B176_RS0107730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_017258225.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-55, bitscore:
                     184.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVIIGNGIAGITTARHIRKQSDHEILVISAESEHFFSRTALMY
                     IYIGHMKYQHTKPYEDWFWEKNRINLHKAYINTIDFDTNTLKTANREEISYDKLVIATG
                     SVTKKIGWPGENLKGVQGLYSKQDVELMETNTQNVKHAVIVGGGLIGIEMAEMLHSRGI
                     EVTFLIRENNYWNSVLPIEEAMLVSRHIAEHGINLIPNTELEEIIGDNDGRVKAVKTKT
                     GKTIDCEFVALTTGVTPNIDFLKESALETDRGILVNDFLETNIPNVYALGDCAQFKNPK
                     ENHPPVEQLWYTGKMQGKALAKTICGQKTKYERGIWFNSAKFLDIEYQTYGLMFNKPFA
                     TEDTFYWEHPKGKIGMRANFSKTDGSLSGFNFFGMRFKQTVADTWIRNGNHISNCIAQL
                     NEGFFDAEFNKNHHKKIVESFNTAHPKHQATIAKKKKFLIF"
     gene            2072..3604
                     /locus_tag="B176_RS0107735"
     CDS             2072..3604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258226.1"
                     /locus_tag="B176_RS0107735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4Fe-4S binding protein"
                     /protein_id="WP_017258226.1"
                     /transl_table=11
                     /translation="MKIIQKIGLAIFLICFAIFISLLGLGKYQLTEVSFKASVTDSTHQ
                     ALLAPNIQQMLGKTYDSKIDFITDYNKSLDKTNQKFKDNQEWDKVIYTDYALAITKNST
                     IGFVKDNQMLLFYICFVISALGGAIYMVADLFIHPVAGIKNNDIFKRSITSRGIIAIFF
                     SVFLVVFYLFLYKAPAYISNWVLLVDPLSFSLTGGEASHWFLYGFLYSIIMLTMGIRMY
                     VKYRHNTYQMVRTTSVIFFQLAFAFMIPNILTKLQLPAMDFKNMWPLDYTFFFDYRLDS
                     LLSAGMLGYWMLGWGIFLFVVGVPVMVYFFGKRWYCSWVCGCGGLAETFGDPFRQLSDK
                     SLKAWKYERVIVHSVLVFAVIMTAAVLYTFFTGASTILGINTYAIREIYSFAIGFVFAG
                     AIGTGFYPLMGNRVWCRFGCPLAAYLGLVQRFKSRFRITTNGAQCISCGNCSTYCEMGI
                     DVRAYAQKGENIIRASCVGCGVCAAVCPRGVLKLENLAEEGRFDIYTRPEEQ"
     gene            3604..4308
                     /locus_tag="B176_RS0107740"
     CDS             3604..4308
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258227.1"
                     /locus_tag="B176_RS0107740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_017258227.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.1e-20,
                     bitscore: 69.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVENLESRNIYVIIPAYNEEKSIAKVINDIPKSIVKEVIVGNNNS
                     KDNTQLEAENAGATVVFAPIAGYGNACLKGIEYLKAKAKPQDIIVFLDGDYSDYPDEIP
                     KIIAPIDNREADLVIGSRALGVKQSGSMTLPQEFGNWLATHLMDWFYKVKFTDLGPFRA
                     VSWHNLMLINMQDKTYGWTVEMQVKAAKLNLKCVEVPVKYRKRIGVSKVSGTIKGVIMA
                     GYKIIWTIFKNL"
     cand_cluster    3696..25771
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    3696..25771
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[13695:15771](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13696..15771
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            4321..5778
                     /locus_tag="B176_RS0107745"
     CDS             4321..5778
                     /EC_number="2.4.1.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258228.1"
                     /locus_tag="B176_RS0107745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cellulose synthase family protein"
                     /protein_id="WP_017258228.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-18,
                     bitscore: 63.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIWQIAILVLYVISLTVILLFSLGQAFLIYFYLKSKKATPEKISI
                     AGDLPIITIQLPLFNELYVTERLLNAVCSLDYPKDKLEIQVLDDSTDDSLLLTKKLVAE
                     KLLQGFDIKQITRSKNIGFKAGALQNGLNQAKGELIAIFDADFLPESDFLTKLIPYFNN
                     PKIGMVQSRWGHINEDYSLLTQVQGFGLDGHFTVEQTGRNSAHLFMNFNGTAGIWRKKC
                     IVEAGGWQHDTLTEDLDLSYRAQLKGWEFKYVEEITTPAELPVALNAFKSQQHRWTKGA
                     IETSKKMLSQVWKANVGLKRKIFASLHLLNSYAFLFIFLTSVLSIPVLLIKNNTEIPLI
                     YFQFLTVYVIGFLVIVVFYLIASLSKHKNYGTFIKLFPMFLSVSLALSFHNTIAVLEGV
                     FNFKSDFIRTPKFNVTTLKDNFKSNIYVQHKLPASFYMEVFLCFYFLTGIIGAFYYHDF
                     GLLPFHLMLFTGFCVLNFYSVKGILTK"
     misc_feature    complement(4327..4339)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.58"
                     /tool="antismash"
     gene            complement(5959..6480)
                     /locus_tag="B176_RS0107750"
     CDS             complement(5959..6480)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258229.1"
                     /locus_tag="B176_RS0107750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2911 domain-containing protein"
                     /protein_id="WP_017258229.1"
                     /transl_table=11
                     /translation="MKKQIAFFACLFIFFATVKVSAQTDKSNRPSPPDKVTATIKSGAV
                     ITVDYSQPSVKGRTIGKEIAPFGKVWRTGANEATVFEVSKAVKINGKDLPAGKYGLFTI
                     PGESEWTIIFNKTWKQWGSGKYAEADDVLRINVKAKTAKDATEKMTFNVDKSGEVKLMW
                     GNIIVPFSVK"
     gene            6657..8996
                     /locus_tag="B176_RS0107755"
     CDS             6657..8996
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258230.1"
                     /locus_tag="B176_RS0107755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent receptor"
                     /protein_id="WP_017258230.1"
                     /transl_table=11
                     /translation="MNLKHLFFYLFIASFIINITTANAQKNNILNGVIKDATTGETLIG
                     ASVQVNGTTSLGTVTNAYGYYSLAIPAGIYEVIYSYVGYQTIKKNISFSGDLTQNIALF
                     SSNQLNEVIVNAEKRNNNVENPLMGVQKLNVKEINNIPVLFGERDILKTLQLLPGIKSA
                     GEGNSGFYVRGGSTDHNLILLDEAPVYNASHLLGFFSTFNSDAIKDVTVYKGGMPAQYG
                     GRLASVLDIKMNDGNKKDYTIEGGIGLIASRLKVEGPIEKDKSSFMISGRRTYADSFLA
                     FSSDSSVKGSRLYFYDLNAKVNFILDSKNILYLSGYFGRDKLGLKDSFGFDWGNTTGTI
                     RLNHLFSNRLFSNTSLIYSNYNYLIQSLLEDNDFSVKSSIKDFNLKQDFQFTANNAHEI
                     KFGLNAIHHTITPGKITASQTSSVNESEIENRKGLELAVYFSDEYKVSEKLNVAYGARF
                     SNYAALGAGTFKTYDTNGDITGSETYKSGELVKNYFNLEPRLSAAYQLSESKSLKASFT
                     RNTQNLHLMSNSTATSPTDLYIMNSNNVKPEIADQFALGYFSNFRNDSYEFSTEIYYKD
                     MKNQIEYRNGTDLRGNQNVEGDLLFGDGRAYGIELFLKKRFGDFNGWIGYTLAKTERQF
                     AQINDGKWFNAKQDRTHDLSIVGIYKASKRWTLSSTFVYSTGTAVTYPSGKYQLNGETV
                     FYYSEKNGYRTPAYHRLDLSATLEPKLVPNRKYQSSWSFGIYNAYNRKNPFSIDFKDNP
                     DNPTKTQAVQTSLFGIIPSVTWNFKF"
     gene            9000..9797
                     /locus_tag="B176_RS0107760"
     CDS             9000..9797
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025420.5"
                     /locus_tag="B176_RS0107760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4249 family protein"
                     /protein_id="WP_017258231.1"
                     /transl_table=11
                     /translation="MRAFYIIFFAITTSVFFSACEKVIDLDLKNTKPVIVIEANVNDNF
                     SQQVVKVTQTKPFTEDNTIVPVTDAVITLKDLTDNRTYNFTLTDNEGTYLSTNFRGKPG
                     NTYELNVSANNQVYIAKSTMPKKVLLDSISVAEVTFFGETNKYIKVHYADPIQYENQYR
                     YLLTVNQKPSKGYFVDSDRFNNGKYVSNTLFDSDNDLKSGDEIKVESQCIDMNIYRYFF
                     AISQISGNGGPPTAPSNPDSNFNNGALGYFNAHTTEVKMATIQ"
     misc_feature    9892..9905
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.5"
                     /tool="antismash"
     gene            10001..10276
                     /locus_tag="B176_RS0107765"
     CDS             10001..10276
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="B176_RS0107765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_017258232.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.4e-17,
                     bitscore: 59.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.5e-12, bitscore: 41.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFLSKKIIPSENAVVQEMGEDIVILNLKTEHFYELKEVGKRIWE
                     LLSENHSYTLTFEAIKGEYEVSSEQLHTDMERIINGLIKAELIKIN"
     aSDomain        10028..10270
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_B176_RS0107765_Stand_Alone_Lasso_RRE.
                     1"
                     /evalue="4.60E-19"
                     /identifier="RREFam002.1"
                     /label="B176_RS0107765"
                     /locus_tag="B176_RS0107765"
                     /protein_end="90"
                     /protein_start="9"
                     /score="59.2"
                     /tool="antismash"
                     /translation="PSENAVVQEMGEDIVILNLKTEHFYELKEVGKRIWELLSENHSYT
                     LTFEAIKGEYEVSSEQLHTDMERIINGLIKAELIKI"
     gene            10276..10719
                     /locus_tag="B176_RS0107770"
     CDS             10276..10719
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="B176_RS0107770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_017258233.1"
                     /sec_met_domain="PF13471 (E-value: 4.3e-16, bitscore: 54.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYCSNELNKVNKCLRSQDNLVFWTRVFTIFTEGILLATSLKTTEK
                     LLSVFKKHTLTLDPEEKIIIVDRYFTIISEINQQSYLKGRCLSQSLILRLLLNRKGILS
                     HLKIGMRQLNGKLDVHAWLEIDNKPINEHISVTKNYLKIINKS"
     gene            10738..12558
                     /locus_tag="B176_RS0107775"
     CDS             10738..12558
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="B176_RS0107775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthetase B"
                     /protein_id="WP_017258234.1"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-19, bitscore:
                     65.3, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.5e-15, bitscore:
                     52.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGFVGIITSKLEQFDIDILDIATSSMCQTCDDYSGSWRSEKADL
                     RFAWLKTFDDTDDEHLPFTMDENIRIIGDVRLDNRIKLIGALKFIFGDEISNSTPDSYL
                     VLYAYKQWGERCLDHISGDYAFAIWNEKEDYLFCARDHFGLVPFYYTQLNDKFLFTNFY
                     TSLKDVPNLISELDDDVVKSYLSAGLNNYFDQTIYKDLKKLPPAHQLIYKNGVAHVSRY
                     WDVPNQISPIRYKTTKEYVEHFYQLFEQSINDRTRNSKVASSLSGGMDSSAITAVTKKV
                     LNECYGANHELKCFNIVYKYLVNEKEGFFGETIAKHLDIPINQYVAEDYLKKILKPLVS
                     WLPEPIGVPHATPESQILSDVETFSRTYLTGFGGDPLFEYGESAKQKLKEQGYKVQSYK
                     DEILFYRVFGRFSGTSLRHKLIGLIKSKPKKNFKKSINNHKYSLFKNVFSFSKKTENLD
                     SLRTYFGMVKNPFWSSLFEMSYPGFNGYKVKVRQPFFSLDLFLFIIALPPHLLYKKSLL
                     RMAMTPYLPTAVITRPKTLIFKNAHFENLQNHNIAEVLKNSISKKNKVFIGNADMKSLI
                     EEATKSDTLANSDSDLLIIFTIMSWNNCVL"
     gene            12591..12743
                     /locus_tag="B176_RS0107780"
     CDS             12591..12743
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B176_RS0107780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_154647925.1"
                     /transl_table=11
                     /translation="MNKEETTGNSKKNYAAPELKELGKIGEITNTTSADSTHTQDGGGG
                     PNYYS"
     gene            12758..13693
                     /locus_tag="B176_RS0107785"
     CDS             12758..13693
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="B176_RS0107785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_017258236.1"
                     /transl_table=11
                     /translation="MKFKIEFHNLTDFDFLLLKEKLAFKPHEQKFSPNIFGENFYTGSS
                     FEYGNCYLFEYRDEQKPMVSFIITSGGKNVFCNYQIEVSPQTVSSLIKGNIKKFCLQEQ
                     GYFCLHASAMQINEKIILFMGKKGAGKSTLASFFHLQGHDIWCDDYSLLQQEKNCFLSY
                     QGETSLKINPDILSALNIPKQKVKNVFDLSDGFKKSNQYKTSSSKVYFRNDKPVENSNP
                     KQVAAVFFLQQRSFDPALLIEPMKKSEALSTLMEEILLPGFNSKEYLKTYFQSSLKLLE
                     HVPCYKIHASNEITRISEVYHSVFETLNFS"
     gene            13696..15771
                     /locus_tag="B176_RS0107790"
     CDS             13696..15771
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.5"
                     /locus_tag="B176_RS0107790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_017258237.1"
                     /sec_met_domain="T2TS (E-value: 1.3e-13, bitscore: 46.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQAADEYPLLGAAKDFFCTLPETIVSAPQLDLLKKAAAFFPPII
                     RFALECRLNKQDQVDLQFCIRRDEDDLASILSWFERKLSGNGEDQLLLSFLKEWADKNS
                     FYHKSIPEIFLELDVNSPNLNVPLLFFELETSLTSTQRKDYSLFILNNTLGKNKPYYKL
                     LETIIEACPDPAYLAYLGILFSRNNDVLRVNIKKLPYCSVVPFLQKTGYKWLSKELEYW
                     LSLIYTYADRITLCIDIGSEIYPKIGFECFWNGQPSTETYWKDFIEKLKLDSILEKDKI
                     KTILEWNEDVFPGKIENWPSHLWLDSLGKSESEFTYLKKWISHLKLSYQPENEIEIKAY
                     LAYESLWMSQNTINLDSLQKQENQIYDEPQELEKVIDKGIDFLLSNQTQAGWWKDFHLE
                     PGTSDEWVTAYVAYYLSNLKTQKTQKSLEKAWDILKTRYRMNEGWGYNALTRGDADSTT
                     WVLHFTNSENLIGNLDICFLSIVEKHISEDGGIVTYAKRRSLEKEALVATSVLFNGWQI
                     PHNCVTAAYALTGKQHAIDYLINQQDKDGFWYGYWWDGYEYATGLATEALYSKNAEKYK
                     KSIESAINWATHEANRILNASFPNTFKLAFLLRILLCDNSEKENSILKQKITTVLINSQ
                     EQQGCWKSDAILRSPNSNDRNHENGKNIPVFKDQMKNFTTVTVLDALNKYALSLIK"
     gene            complement(15754..16929)
                     /locus_tag="B176_RS0107795"
     CDS             complement(15754..16929)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.5"
                     /locus_tag="B176_RS0107795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_017258238.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 4.5e-33, bitscore:
                     110.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSIGHLKTIYGNEETLIILITRLYFDKQSVGEVNDFLEKEEINW
                     LLFYKLVQLNDIRGFVYEIVITSNISIDQSVFNALKKDTVGIILFGKYQLQLLNHLSQQ
                     FSNLGIRVINYKGVRFANRYYRSLSMRESADIDFLIKKDDLSKLRECLLSNDFISTYDV
                     SEHQIGFLKKYQRELSLKSPKDKLGINCSVELQWKLVENYFGKFYEYDFLAKHLTHDSN
                     GTISMALSPTYDFLCIASHHLIREPLLKFKYLIDLACIIDKSGKNLNWEEIAAGFKRYK
                     FSPFLWSGVNALEEIVGIKIPLSEKPAIKYHLFSFMKAKNDRENLFKKIKLIGLKLDFT
                     ERIKFKVKAYSWLLVPNTNDLSLTDKPAWAIPLIIPTKSFKLFYSFLFNKR"
     gene            complement(17259..17630)
                     /locus_tag="B176_RS0107805"
     CDS             complement(17259..17630)
                     /EC_number="4.2.3.3"
                     /GO_function="GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258240.1"
                     /locus_tag="B176_RS0107805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylglyoxal synthase"
                     /protein_id="WP_017258240.1"
                     /transl_table=11
                     /translation="MKKRIALIAHDGKKAEMVGFVKDHLEILSRMDLVATGTTGGYVEQ
                     TGLQVNKKLSGPNGGDAQIAAMAAEDLLDGILFFRDPLGKHPHEPDVQMLMRICDVHNV
                     PIATNPATAKLILEALADD"
     gene            complement(17707..18939)
                     /locus_tag="B176_RS0107810"
     CDS             complement(17707..18939)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258241.1"
                     /locus_tag="B176_RS0107810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleoside recognition domain-containing protein"
                     /protein_id="WP_017258241.1"
                     /transl_table=11
                     /translation="MALNYVWVGFFIISFGVALFRLIFFQDYQIFQEIVNSTFDMSKTG
                     AEISLGLIGLMTFWLGIMKIGEKGGMINIFAKLVGPFFSKIFPEIPKNHPAMGSILMNF
                     SANMLGLDNAATPLGLKAMKELQEINPQKDTASNAQIMFLVLNASSLVLIPTSIMAFRK
                     AAGAVDPSDVFVPCLLATFFSTLVGLVVTATYQKINLFQKTILIYLGSAAAVIGGTLYY
                     FTTLSQDQISIVSSVVGNVLLFSIILSFIILALFRKINVFETFIEGAKEGFEIAVKIIP
                     YLVAILVAVGVFRGSGALDFLVEAIKHLVAFAGLDTGFVPALPVAFMKPLSGSGARGLM
                     VELMNTTGADSFASRVACVIQGSTETTFYVLAIYFGSVSIKKTRHALPAALLAELAGVL
                     AAIFIAYIFFK"
     gene            complement(19059..21908)
                     /locus_tag="B176_RS0107815"
     CDS             complement(19059..21908)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258242.1"
                     /locus_tag="B176_RS0107815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S9 family peptidase"
                     /protein_id="WP_017258242.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2e-23, bitscore:
                     78.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFNIPFLKTKTFLVLLFTCTTFVCFSQKKPVDHSVYDSWESIGS
                     KQISASGKWIGYSIAPQAGDTTLLIKSVKNGSTVFSYPHAQKFTITQDEAFVVFSIIPK
                     FSDTRQAKIKKKKAVDMPKDSLGILNLNSKTLEKIPQVKSFALPDKASNVLAYLLEKEK
                     KDTTKTKKTESLQDAAYFFADEKEKSNEAKEGSVLVLKYLATKDSAKFKGVNDYLLSKD
                     GQYLIYSCSGIKKDSSVKPGVYLFETSSKKTTFLTGGKGLYKNFAFDEKTKQIAFTGNK
                     SEEKALVKPHDLYFYNFTTDSASILVSTKTVGMPQNNHVSENGKVFFSKDGSRVFFGTA
                     PIPVAKDTTIVDFEVAKVDIWNYQDEYLQPMQLANLSKKLKESFLAMVDLKNNKFLQLG
                     TEELNTVNLPEDGNEDFALLSSDFGNRVAMQWDGATLRTAYLINLKTGKKTLVSSNTKT
                     EYKFSPKGNHVLWFDEKEQNWFSYSALTNRKIKIIQEKGSVFGDDENDVPDDAKSYNYG
                     GFTEDEKQVLIYDKYDIWSFNPETGIGKNLTNAFGQQNKTTFRYTALDKEKKSVPQKGE
                     LLLSAFNQLTKQNGWFTKDIAKPGNPIKLVMENYSFSKPIKAENSKMMVYQKENYQNSP
                     DVYASTNFKNELKLSNINPQQANYKWGNAMLVNWITPKGYKATGVLYKPEDFDPKKSYP
                     MIVYFYEKVSDKLFAYQAPAPTPSRLNISYFVSNGYLVFTPDISYEIGYPGKSAEEFIN
                     SGVEYLKQNSWVNGNKIGIQGQSWGGYQVAHLITVTDKYAAAWSGAPVVNMFSAYGGIR
                     WQTGMNRQFQYEKTQSRIGATIWEKPELYTENSPLFRMPNVQTPVVIMANDGDGAVPWY
                     QGIEMFTALRRLGKPVWMLNYNGDEHNLMKRQNRKDISIREQQFFDHYLKGALMPVWMG
                     KGVPATEKGKNWGFDLIKP"
     gene            complement(21898..22278)
                     /locus_tag="B176_RS0107820"
     CDS             complement(21898..22278)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258243.1"
                     /locus_tag="B176_RS0107820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chaperone"
                     /protein_id="WP_017258243.1"
                     /transl_table=11
                     /translation="MQQKIFSVDEYIAQFPTEMQNLLRLLRATIILEIPDAVEVISYGI
                     PTYRVDVNLVHFAGYKKHIGFYPGPNALIKFKSKILAFKHSKGAVQFPINKELPLKLVS
                     EITKYVLIQNQIKPSKKQPNEI"
     gene            22416..23885
                     /gene="gatB"
                     /locus_tag="B176_RS0107825"
     CDS             22416..23885
                     /GO_function="GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /gene="gatB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258244.1"
                     /locus_tag="B176_RS0107825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="WP_017258244.1"
                     /transl_table=11
                     /translation="MNQIINNIEQFEAVIGLEVHVQLSTASKAFCSDSATFGNLPNQNI
                     SPVSLGLPGALPLTNEKAVKYATKLGLAIDSKINQYNFFDRKNYFYADLPKGYQITQDN
                     EPICIGGKLKIRLETGEEKDIILNRIHMEEDAGKSIHDLDADYSYIDLNRAGVALLEVV
                     TEPMISSGEEAAAYLTELRKLVRYLDICDGNMEEGSMRCDANVSVRLKGETKLGNRCEV
                     KNLNSIKNVQRAIEHEIQRQIGLINKGKTIDQNTLNFDAATGKTTPLRSKEMANDYRYF
                     PEPDLLPMVISDEYLEAIKAEMPALPEQLYQQFTKEMGLPSYDALVLTADKAMADYFIA
                     ITKHSTSYKLASNWVMGTLKSFLNETQQGFADLRIPAEEIAAIINLVAHKEINNSQAKN
                     KLFAALVLQPEAKVANLVEELNLIHKKCDNELEGFIITALEKFPDKVKEYQNGKKGVIG
                     LFMGEVMKLSHGKVDPKQANKLIIEKLEGIK"
     gene            23971..25092
                     /locus_tag="B176_RS0107830"
     CDS             23971..25092
                     /GO_function="GO:0016209 - antioxidant activity [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017258245.1"
                     /locus_tag="B176_RS0107830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_017258245.1"
                     /transl_table=11
                     /translation="MKKHFIVGLFGVALFAVSCSNKSEFSIKGSFTNIGDAKKVYLLEL
                     DTFGQMIPIDSTFLNEDKQFTLKSKSVDPEFYQVAVGQRAFFVIAENGDEVELKADLNN
                     PTGSYEIKGSEEADKITEYNKITAVYSQQNGALAEQYSKMITANQENKDQIIAEYNAKA
                     GVIAKPFLEQSMEFIEKNKKSMTAFFAANIMMGMQHDDYESKLIAYSKEAAETFPKNTA
                     ITSFAKQMEATKKVAVGSVAPTISALSTNGKVINLADFKGKYVLVDFWASWCAPCRQEN
                     PNLVATYHRFKDKNFTVLGFSLDDNEDAWKKAIITDKLDWAQVSELRQWDSPTALSYNV
                     SAIPASFVIDPSGKIIAKNLRGEQLNQFLEKTL"
ORIGIN
        1 tcaagaatct gtgcaaacac aaaaatctga tgatgacgtc tcgactgcgg taaaccatac
       61 tgcatttgat aaactgttgc aggcaaacgt ttctaacaaa ggaagtgttg actataaagc
      121 atttgtaaaa gataagaccg ctttagaaaa ttacattgta agtttaacaa aagtagatgc
      181 ccgtaaactt tctaaaaacg aagctattgc cttttggatt aatgcataca acgccttaac
      241 aatagaccaa attgtaagaa attatccggt ggcttccatt actaaaattg ctggcggaaa
      301 agtttgggac cagcccctac cctttaagtt tcaaggaaaa acacttactt taaatgatat
      361 cgaaaaaaaa atattgttaa gtggcgattt atttgacgga agaatccatt ttgcggtaaa
      421 ctgtgctgca ctatcatgcc caaccttatc caacaaagct tttaccggtg caaatgttca
      481 agaaatgtta actaaaaaca caaaagcaac tttagctaat ccagatttta atagaatcac
      541 ggagaaaaat gcctccatct caaaactttt tgattggtat aaagcagatt ttgtaaaggc
      601 agaaggaagt gttgtaaagt ttatcaacag atattctaca actaaaatta gcaatcaaac
      661 taaaatcacc tatcttgatt ataattggag tttaaatgga aaataaattc gataaatcct
      721 taacctcagt atgaaagtag taattattgg aaacggaata gctggcatta ccacagccag
      781 acatatcaga aaacaaagtg accatgaaat tttagttatt tctgctgaat cagaacattt
      841 tttttcccgc actgcgctaa tgtacattta catagggcat atgaaatacc aacataccaa
      901 gccttatgaa gattggtttt gggagaaaaa cagaatcaac cttcataagg cttacatcaa
      961 tactatcgat tttgatacca atacattaaa aacagctaac agagaagaaa tttcttacga
     1021 taaactggta attgctacag gttctgttac taaaaaaatt ggctggcccg gagaaaattt
     1081 aaaaggtgtg caaggtttgt acagcaaaca ggatgtagag ctgatggaaa ccaataccca
     1141 aaacgttaaa catgcagtaa ttgtgggtgg cggtttaatt ggaattgaaa tggcagagat
     1201 gctacatagt cgtggtattg aggttacttt tttaattaga gaaaacaatt attggaatag
     1261 cgtactgcca atagaggaag ctatgttagt gagcaggcac attgcagaac acggtattaa
     1321 tttaatacca aacaccgaat tggaggaaat aatcggtgat aacgatggtc gggtaaaagc
     1381 agttaaaaca aaaaccggaa aaaccattga ctgtgagttt gtggctttaa ctactggtgt
     1441 aacacctaat attgattttt taaaagaatc ggctttagaa acggatagag gaatattggt
     1501 aaatgatttt ttagaaacca acattccaaa tgtttatgca ttgggagatt gtgcgcagtt
     1561 taaaaatcca aaggaaaacc acccgccggt tgaacagctt tggtacacag gtaaaatgca
     1621 gggaaaagct ttggctaaaa ccatttgtgg gcaaaaaaca aaatacgaaa ggggaatttg
     1681 gtttaattcg gccaagtttt tagacattga ataccaaact tatggtttga tgttcaataa
     1741 gccgtttgct acagaagata ctttttactg ggagcacccg aaaggaaaaa tagggatgcg
     1801 ggcaaatttt agtaaaacag atggaagtct tagcggtttc aatttttttg ggatgcgctt
     1861 taaacaaact gttgcagata cgtggattag aaacgggaac catatcagta actgtattgc
     1921 tcaattaaac gaaggttttt ttgatgcaga atttaacaaa aatcaccata aaaaaattgt
     1981 agaaagcttt aatacggcgc atcccaaaca tcaagcaaca atcgctaaaa agaagaaatt
     2041 tttaattttt taatccgatt aaacagaaaa tatgaaaatc attcaaaaaa tcgggttagc
     2101 aatcttttta atttgcttcg caatttttat atcgctgttg ggtttaggca aatatcaact
     2161 tacggaagta agctttaaag cttctgtaac cgacagtacg catcaagctt tattagcacc
     2221 aaacattcaa caaatgctcg gtaaaactta tgatagcaaa atcgatttca tcacagatta
     2281 caacaaatcg ctcgataaaa ccaatcaaaa atttaaggac aaccaagaat gggataaagt
     2341 aatttacact gattatgcct tagcaattac aaaaaacagc accattggtt ttgttaaaga
     2401 caatcaaatg ttgttgtttt atatctgttt tgtaattagt gcattaggcg gtgctattta
     2461 tatggttgct gatctattta tccatcctgt tgcaggtata aaaaacaatg atatttttaa
     2521 aagaagcatc accagccgtg gaattatagc gatattcttt agcgttttct tggttgtatt
     2581 ttacctgttt ctatataaag caccagctta cattagcaat tgggtcttat tggtggatcc
     2641 cttaagtttt tcgctaactg gcggcgaggc tagtcattgg tttttgtacg gcttccttta
     2701 ctccatcatt atgttaacga tgggtattag aatgtatgta aaatatcgcc acaatactta
     2761 ccaaatggta cgaaccactt cggttatatt tttccagttg gcctttgcgt ttatgattcc
     2821 caacatttta accaaactgc agttgcccgc tatggatttt aaaaatatgt ggccattgga
     2881 ttataccttc ttttttgatt atcgcttaga cagcttacta tctgccggaa tgttgggtta
     2941 ttggatgttg ggctggggaa tatttttatt tgttgttggc gtacctgtaa tggtttactt
     3001 tttcggaaaa agatggtatt gtagctgggt ttgtggctgt ggtggcttgg cagaaacctt
     3061 tggagatccg tttcgtcaac tttctgataa aagtttgaaa gcctggaaat acgaacgggt
     3121 gattgtacac agtgttttgg tttttgcagt aattatgacc gctgctgtac tctacacctt
     3181 ctttacaggc gcttctacca tcttaggaat taatacgtat gcaattagag aaatttattc
     3241 ttttgctatt ggttttgttt ttgccggcgc aattggaacg ggtttttatc ctttaatggg
     3301 aaatagggtt tggtgcagat ttggttgtcc gctcgcagct tatttaggtt tagtgcaacg
     3361 gtttaaatca cgatttagaa ttaccaccaa tggcgcacaa tgcatatctt gcggaaattg
     3421 ctccacctat tgcgaaatgg ggatcgacgt tagggcttac gcccaaaaag gagagaacat
     3481 catcagagca tcttgcgtag gttgtggcgt ttgtgcggca gtttgcccaa ggggtgtttt
     3541 aaaattagaa aatttagcag aagaaggtag gtttgatatt tataccagac cagaagagca
     3601 gtaatggtag aaaatttaga aagcaggaat atttacgtaa ttattccggc ttacaacgaa
     3661 gaaaaatcga tagcaaaagt catcaatgat attccaaaat ctattgttaa ggaagttatt
     3721 gttggaaaca ataattcaaa ggacaataca cagcttgagg cagaaaacgc gggagcaaca
     3781 gtagtttttg caccaattgc tggttacgga aatgcttgct taaaaggcat tgaatattta
     3841 aaagcaaaag caaaacctca agatatcatc gtttttttag atggcgatta ttccgattac
     3901 cctgatgaaa ttcccaagat aattgcaccc attgacaacc gcgaagccga tttagtgata
     3961 ggttctagag ctttaggggt aaaacaaagt ggctctatga ctttacccca agagtttgga
     4021 aactggctgg caacacattt aatggattgg ttctacaaag ttaagtttac agatttaggt
     4081 ccgtttaggg cagttagctg gcataatcta atgctgatta atatgcagga caaaacctat
     4141 ggttggacag tggagatgca ggtaaaagcg gctaaactca atttaaaatg tgtggaagtg
     4201 ccagttaagt acagaaaacg gattggtgta agtaaagttt ctggaaccat aaagggcgtg
     4261 attatggctg gctataaaat catctggaca atttttaaaa atctgtaatt cataaaaaac
     4321 atgatttggc aaattgcaat attggttttg tacgttattt cccttacagt aattctgctg
     4381 tttagcctag ggcaagcttt tctaatttat ttttatctga aatcaaaaaa agctacaccc
     4441 gaaaaaataa gtatcgcggg tgatttaccc ataattacca tacagcttcc tctttttaac
     4501 gagctttatg ttacagaaag actattaaac gctgtttgta gtttagatta cccaaaagat
     4561 aaattagaaa ttcaggtttt ggacgactca accgacgatt cattgcttct tacaaaaaag
     4621 cttgtcgcag aaaaactgct gcagggtttt gacatcaagc aaatcaccag atctaaaaat
     4681 attggattta aggctggtgc gttacaaaac ggattaaacc aagctaaagg tgaacttatc
     4741 gctatttttg atgctgattt tttacccgaa tcggattttt taaccaagct tatcccctac
     4801 tttaacaatc cgaaaattgg gatggtacaa agtagatggg gacacataaa cgaggattac
     4861 tctttgttaa cccaagtaca gggttttggt ttagacgggc attttaccgt agagcagacc
     4921 ggaagaaatt cggcacatct gtttatgaat tttaatggaa ccgctggtat atggcgtaaa
     4981 aaatgcattg tagaagcggg tggctggcaa catgatacct taacagagga tttagattta
     5041 agttaccgag cccagctaaa aggttgggag ttcaaatatg ttgaagagat caccacaccc
     5101 gcagaactcc ccgtagcatt aaatgcattt aaatcacagc aacatcgttg gactaaagga
     5161 gcaatagaaa cttctaaaaa aatgctatca caggtttgga aagccaatgt gggtttaaaa
     5221 cgaaagatat ttgcgagttt gcacttacta aattcctacg ctttcctgtt tattttctta
     5281 accagcgtac tcagcattcc ggtattactg attaaaaaca atacggaaat cccacttatt
     5341 tattttcagt ttttaacggt ttatgtaatt ggttttctgg tgattgtggt gttttatctc
     5401 attgcaagcc tttccaaaca taaaaactac ggaactttta taaaactttt tccaatgttt
     5461 ctttccgttt cattggcttt aagtttccat aataccatcg ctgttttaga gggtgttttt
     5521 aattttaagt ctgattttat acgtacgcct aaatttaatg tcaccactct aaaagataat
     5581 ttcaagagca acatctatgt tcagcataaa ctgccggcat ctttttatat ggaagtattt
     5641 ttatgttttt actttttaac gggcattatt ggtgcttttt attaccatga ttttggattg
     5701 ttgccttttc atctgatgct ttttacagga ttttgtgtac tgaattttta ttctgtaaaa
     5761 ggaattttaa cgaagtaata ttgttgcgtt aagtatagca gtggataccc gccctgtggc
     5821 taaggctttg agcagtatga acgaatagcc tgttaaaacg cccatgaaat atttttcaaa
     5881 taaaatcgaa attacctcca acaaaaaaag gcttatgatt ttaacaaacc ataagcctaa
     5941 taatcaaaaa atattcaatt acttaaccga aaacggtaca attatatttc cccacatcaa
     6001 cttaacttcg ccagatttgt cgacgttaaa agtcattttt tcagtcgcat cttttgctgt
     6061 tttcgctttt acattaatac gtaaaacatc gtcagcttcg gcgtatttac cgcttcccca
     6121 ctgtttccac gttttattaa aaataattgt ccactcactt tctccgggaa tggtgaacag
     6181 cccatattta ccagctggca aatcttttcc attaattttt acggctttac ttacctcaaa
     6241 aacagtagct tcattagctc cggtgcgcca aaccttgcca aatggcgcaa tttctttacc
     6301 aatcgttctg ccttttacag aaggctggct gtaatcaacc gtaataactg cgcctgattt
     6361 aatggtcgct gtaactttat caggcggact tggtctatta cttttatctg tttgcgcact
     6421 tacttttaca gtcgcaaaaa agataaatag acaggcaaaa aatgcaattt gttttttcat
     6481 aatctgtttt tattttaatg gggtttatag ctaaacgaat tttattgatg attgtttttt
     6541 attataaaac acaaagcaaa catttttgaa agctttatgt ttaagcatta tcatacaagt
     6601 taagcattaa gctttattat ctttgcaaaa aaaatttcaa aacatattaa atattgatga
     6661 atcttaaaca cctattcttt tacctcttta tagctagctt tattatcaat attacaacag
     6721 caaatgctca aaaaaacaac attttaaatg gagttatcaa agatgcaaca acgggagaaa
     6781 ccttaattgg cgcatctgtt caggtaaatg gcaccacttc tttaggtact gttaccaatg
     6841 cttatggcta ttattcgtta gccattcctg ctggtattta cgaagtaatt tacagttatg
     6901 taggctatca aacaatcaaa aaaaacatca gtttttctgg agatttaacg cagaatatag
     6961 cacttttttc ctcaaatcaa ctaaacgagg tcattgtgaa cgccgaaaag cgaaacaata
     7021 atgttgaaaa tcctttaatg ggcgtacaaa aactgaacgt taaagaaata aacaatatac
     7081 ccgtattatt tggcgaaaga gatattttaa aaacgctaca attgttaccc ggtataaaat
     7141 ccgccggcga aggcaatagc ggtttttacg ttagaggcgg ttctacagac cacaacctta
     7201 tattgttaga cgaagcgccg gtttataacg cctctcacct attgggtttt ttctcaacct
     7261 ttaattctga tgcgataaaa gacgttacgg tttataaagg tggtatgcca gcacaatacg
     7321 gtggtagatt agcgtctgtt ttagatatta agatgaacga tggcaacaag aaagattaca
     7381 caattgaagg tggaattggc ttaattgcat caaggttgaa agttgaagga cccattgaaa
     7441 aagataagag ttcttttatg attagtggtc gaagaacgta tgcggatagt ttcctagctt
     7501 tctcctcaga cagtagcgtt aagggtagta gactttattt ttacgactta aatgccaagg
     7561 ttaactttat cttagacagt aaaaacatcc tttacctttc tggctatttt ggcagagaca
     7621 aactaggctt aaaagacagc tttggctttg attggggcaa tactacagga acaataaggt
     7681 taaatcattt attttctaat cgcctgtttt ccaatacttc tttaatttac agtaactaca
     7741 actatttaat tcagagtctt ttggaggata atgattttag tgtaaaatcg tctatcaaag
     7801 attttaacct gaaacaggat ttccagttta cggcaaacaa tgcccatgag ataaaatttg
     7861 gtttaaacgc aatccaccat accattacac ccggtaaaat aacagccagc caaacttcaa
     7921 gcgttaacga aagtgaaatt gagaacagaa aaggcttaga actggcagtt tatttttctg
     7981 acgaatataa ggtgagcgaa aaacttaatg tagcttacgg cgctagattt agtaattatg
     8041 ctgctttagg agcaggaaca tttaaaacct acgatacaaa cggagacatc accggctctg
     8101 aaacctataa atctggcgag ctggttaaaa actatttcaa tctagaacca cgcctatctg
     8161 cagcttatca gctttcggaa agcaaatctt tgaaagcatc atttacccgc aatacccaga
     8221 acttacactt aatgtctaat tcaacagcaa catcgcctac agatttatac attatgaaca
     8281 gcaataacgt aaaacccgaa attgctgatc agtttgcgct gggctatttt agcaatttcc
     8341 gaaatgatag ctacgagttt tctaccgaga tctattataa ggatatgaaa aaccaaattg
     8401 agtaccgaaa cggtactgat ttgcgtggaa accaaaatgt agaaggtgat ttgttatttg
     8461 gcgacggcag agcttacgga attgaactgt ttttaaagaa acgtttcggc gattttaacg
     8521 gttggattgg ttatacttta gcaaaaacag aaagacagtt tgcgcagatc aatgatggca
     8581 aatggtttaa tgcaaaacag gaccgtacgc atgatttatc aatagttggt atttataaag
     8641 ccagtaaacg ctggacgctt tcttccactt ttgtttacag caccggaact gcagttactt
     8701 accctagcgg aaagtatcag cttaacggag aaactgtttt ttattattca gaaaaaaacg
     8761 gataccgcac tcctgcttat caccgtttag atttatcggc aactttagaa cctaagcttg
     8821 taccaaatag gaaataccaa tcaagctggt cgttcggtat ttataatgca tacaacagaa
     8881 agaacccttt ttctattgat tttaaagaca atccagacaa tcctacaaaa acacaagcgg
     8941 tacaaacttc gttatttggc attattccat cagttacctg gaattttaaa ttttaaaaca
     9001 tgagagcatt ttacattata ttttttgcca ttactacatc ggtgtttttt agtgcctgcg
     9061 aaaaggtgat tgatctagat ttaaagaaca caaaacctgt tattgtaatt gaggccaacg
     9121 taaatgataa tttttcgcaa caagttgtta aagtaacaca aaccaagcct tttacagagg
     9181 ataacaccat agttcccgtt actgatgctg taattacttt aaaggattta acagataaca
     9241 gaacttacaa ttttaccctg acagataatg aaggaaccta cctttcaact aacttccgcg
     9301 gaaaacccgg aaacacctac gaactgaatg taagtgcgaa taaccaggtt tacattgcaa
     9361 aatcaacaat gccaaaaaaa gtattgttag attctatatc tgtggcagag gttacgtttt
     9421 ttggagaaac aaataaatat atcaaggttc attatgctga tccaattcaa tatgagaacc
     9481 agtaccgtta ccttttaacc gttaaccaaa agccatcgaa aggttatttt gtagattcgg
     9541 accggtttaa taatggaaaa tatgtaagca acaccctatt tgatagtgat aacgacttaa
     9601 aatctggaga tgagatcaaa gtagagtctc agtgtattga tatgaacatc tatcgctact
     9661 tctttgccat ttcgcagatt agcggaaacg gtggcccgcc tactgcacct tcaaatcccg
     9721 attcaaattt caataatgga gctttggggt attttaatgc gcacactacg gaggttaaaa
     9781 tggcaacgat acagtagtta agctaccgaa ccttttgttt acatcgatct gtaatgattg
     9841 tttgcactat gtagaatttc aatactaaaa acgaagttta aatctaaaaa tagaataaat
     9901 gttctcatct atttaatcta aactatattc aaaattttta ccttcgcttt tattcaaaaa
     9961 caaactttta taaactatcc caaacaaaaa attaaaacta atgagttttc taagtaaaaa
    10021 aattattcct tccgaaaatg ctgttgttca agaaatgggt gaagatattg ttatacttaa
    10081 tctaaaaaca gaacattttt atgaacttaa agaagttgga aagagaatct gggaattatt
    10141 atctgaaaat catagttata ctttaacatt tgaagcgata aaaggggagt atgaggtttc
    10201 atctgaacag cttcataccg atatggagcg tataataaat ggactaataa aagcggaact
    10261 tatcaaaata aattaatgta ttgtagtaat gagctaaata aggttaataa atgtttaaga
    10321 tctcaagata atttagtttt ttggacaaga gtattcacta tatttaccga gggcattctt
    10381 cttgcaacca gcttaaaaac caccgaaaaa ctattgtccg tgtttaaaaa acacacctta
    10441 acactagacc cagaagaaaa aataattatt gttgatagat atttcactat tattagcgaa
    10501 attaaccagc aatcttacct aaaaggaaga tgcctttcac agtctttaat attacgttta
    10561 cttttaaaca gaaaaggaat cttatctcat ctaaagatag gaatgagaca attaaacgga
    10621 aagttggatg ttcatgcttg gctagaaatt gataataaac caatcaatga gcacatttct
    10681 gtaaccaaaa attatctcaa aataataaat aagagctagg ccaaattttc aattttaatg
    10741 agcggattcg taggaattat aacttctaaa ttagagcagt ttgatataga tatcttagac
    10801 attgcaacaa gctctatgtg ccaaacttgt gatgattatt cgggttcgtg gcgaagcgag
    10861 aaagctgatt tacgttttgc gtggttaaaa accttcgatg atactgatga tgagcatctt
    10921 ccatttacaa tggatgaaaa tatccgaatt attggagatg tgcgactaga taatcgtatc
    10981 aaacttatag gggcgctaaa gtttatattt ggagatgaga tcagtaattc aactccagat
    11041 tcctacttgg tcctatatgc gtataagcaa tggggagagc gttgcctaga ccacatttca
    11101 ggagattatg catttgcaat ttggaatgag aaagaagatt atcttttctg cgcccgagat
    11161 cattttggtc ttgtgccatt ttattacacc caactcaacg ataagtttct attcacaaat
    11221 ttttacacat ccttaaaaga tgtaccgaat cttatttcag agctcgatga cgatgttgta
    11281 aagtcttatt tatccgctgg attgaacaat tattttgatc aaactattta taaagaccta
    11341 aaaaaactcc caccagctca ccaacttatt tataaaaatg gagttgctca tgtaagtcgc
    11401 tattgggatg taccaaatca gattagccct attcgttaca aaaccacgaa ggaatacgtg
    11461 gagcacttct atcaattatt tgagcaatct ataaatgatc gtacccgaaa cagtaaggtt
    11521 gcgtcttctt taagtggagg tatggatagc tctgcaataa ccgcagtgac gaaaaaagtt
    11581 ttaaatgagt gttatggtgc taaccatgag ttaaaatgct ttaatattgt ttataaatat
    11641 cttgtgaacg agaaagaagg tttttttgga gaaacgatag cgaaacattt agatataccg
    11701 ataaaccaat acgtagcaga ggattacctt aaaaaaattt taaaaccact tgtctcttgg
    11761 cttcccgaac caattggggt cccgcatgca acccctgaat ctcagatact ctcagacgta
    11821 gaaacatttt cgcgaactta tttaactggg ttcggtggag atcctttatt tgaatatgga
    11881 gaatcggcta aacaaaagct taaagagcaa ggctacaaag ttcagtcata taaagacgag
    11941 attttattct accgcgtttt cggtcgcttt tctggaacaa gccttcggca taaattgata
    12001 ggtttaatta aatcaaaacc taaaaaaaac tttaaaaagt caatcaacaa ccacaaatat
    12061 tctcttttca aaaatgtttt ttctttctcc aaaaaaaccg agaatcttga ttctttgcgt
    12121 acttactttg gaatggttaa aaatccgttt tggtcctcgc tatttgagat gtcttatcca
    12181 ggatttaatg gatataaagt taaagtacga caacccttct tttctttaga tttatttctt
    12241 tttatcattg cattacctcc acatctgctt tataaaaaat cattgctacg catggcaatg
    12301 acgccttatc tcccaaccgc agttattacc cgaccaaaaa cgcttatttt taaaaatgct
    12361 cattttgaaa atttacaaaa tcataatata gctgaagtac ttaaaaacag tatttctaaa
    12421 aaaaataaag ttttcattgg aaatgcagat atgaaatctt taatagaaga agctactaaa
    12481 tctgatacat tagctaattc agatagcgac ctacttatta tttttacaat catgtcttgg
    12541 aacaattgtg ttttataaaa aaaacgttac tttcgttaaa aaacgacgat atgaacaaag
    12601 aagaaactac tggaaactct aaaaaaaact acgctgcacc agaactgaag gaattgggga
    12661 aaattggaga aattacgaat accacaagtg cagacagcac tcatactcaa gatggtggtg
    12721 gtggcccaaa ttactattca taatttgaag ttattgtgtg aagtttaaaa tagaattcca
    12781 caatctaaca gattttgatt ttttgctact gaaagaaaaa ttagcattta agcctcatga
    12841 acaaaaattt tcgccaaata tatttggcga aaatttttat acaggaagta gttttgaata
    12901 tggtaattgc tatctgtttg agtatcgtga tgaacaaaaa ccgatggtta gcttcatcat
    12961 tacttctggt ggcaaaaatg ttttctgtaa ttatcagatt gaagtctccc ctcaaacagt
    13021 tagctcgtta attaagggta acatcaaaaa gttttgtttg caagaacagg ggtatttttg
    13081 cttgcatgct tcggcaatgc agataaacga aaaaataata ttgtttatgg gtaaaaaagg
    13141 tgctggaaaa tcaacgctag caagtttttt tcacttacag ggacacgata tctggtgcga
    13201 cgattattct ttgctacagc aagaaaagaa ctgctttctt tcttatcaag gtgaaacctc
    13261 actcaaaatc aatccagata ttttatctgc tttaaatatt cctaagcaaa aagtaaaaaa
    13321 tgtatttgat ctttctgatg gttttaaaaa aagcaatcaa tataaaacct ctagttctaa
    13381 ggtctacttc cgcaatgata aacctgttga gaatagcaac ccaaaacagg ttgcagccgt
    13441 atttttttta cagcaaagaa gttttgatcc agcgctttta attgaaccga tgaagaaatc
    13501 cgaagcactt tcaaccttaa tggaggaaat actattgcct ggttttaatt caaaagaata
    13561 cctaaaaact tatttccaat catcattaaa acttttggaa catgtacctt gttacaaaat
    13621 acatgcttca aacgaaatta cccgaattag tgaagtatac cattctgtgt ttgaaacttt
    13681 aaacttttct taaacatgtt gcaagctgct gatgaatatc cgctactagg tgcggcaaag
    13741 gatttctttt gtacgctccc cgaaacaatt gtttccgctc cccagctaga tttgcttaaa
    13801 aaggctgctg ctttttttcc tcctattatc cgctttgcat tagagtgccg cttgaataag
    13861 caagatcagg tcgatctgca gttttgtatt agaagagacg aggacgactt ggcatcaatt
    13921 ttaagctggt ttgagagaaa actttctgga aatggagaag atcaactact tctttctttt
    13981 ttaaaagagt gggcagataa gaactctttt tatcacaaaa gtatacctga gatattttta
    14041 gaacttgatg ttaattcacc taatttaaat gtaccccttt tattttttga gctagagacc
    14101 agccttacca gcactcaaag aaaagattat tctttattta tcttaaataa tacgttaggt
    14161 aaaaacaaac cttattataa gttattagag acgattatag aagcctgtcc agatcctgca
    14221 tacctagcat acttaggaat tctattttct agaaataatg acgttttacg tgtaaatata
    14281 aaaaaattac catactgctc tgtagttcct tttttacaga aaactggtta taagtggctt
    14341 agtaaagagc tcgagtattg gctgtcgtta atatatactt acgcagaccg tataacttta
    14401 tgtatcgata ttggctcaga aatttatcca aaaattggtt ttgaatgttt ttggaatggg
    14461 caacccagca ccgaaactta ttggaaggat tttattgaaa agctgaaact tgacagtata
    14521 cttgaaaaag acaaaataaa aacaatacta gaatggaacg aagatgtttt tccggggaag
    14581 attgagaatt ggccaagtca tctttggcta gattcattag gtaaatccga aagtgaattt
    14641 acctacttaa aaaagtggat ttctcattta aaactatctt accagccaga gaatgaaatt
    14701 gaaataaagg cttatctcgc ttatgaaagt ttatggatgt ctcagaatac gattaattta
    14761 gatagcttac aaaagcaaga aaatcaaatt tacgatgagc ctcaagaact agaaaaagta
    14821 atcgacaaag gaatcgactt tcttttatca aaccaaactc aagctggctg gtggaaagat
    14881 tttcacctag agccaggaac tagcgatgaa tgggtaacag cttatgttgc ttattacctt
    14941 tctaatttaa aaactcaaaa aactcaaaaa tcactagaaa aagcttggga tatattaaag
    15001 acgagatacc gcatgaatga aggttggggt tataatgcct taacacgagg agacgcggat
    15061 agcaccacat gggttttgca ctttactaac tccgagaact taattggcaa ccttgatata
    15121 tgttttttaa gtatagtgga aaaacatatt tcagaggatg gcggtatagt tacatacgca
    15181 aagcgtcgct ctttagaaaa agaagcatta gttgccacta gtgtactttt caacggctgg
    15241 caaatacccc ataattgcgt aaccgcagca tatgcactaa cgggaaaaca acatgctatt
    15301 gattacctaa ttaatcaaca agataaagac ggtttttggt atggttactg gtgggatggt
    15361 tacgagtatg cgacagggct cgctacagaa gcactttata gtaaaaacgc agaaaaatat
    15421 aagaaatcaa ttgaaagtgc tataaactgg gcaacgcatg aggcaaatag aatattaaat
    15481 gcatcctttc ctaacacttt caaacttgct tttctattgc ggatactatt atgcgataat
    15541 tccgaaaaag aaaattctat actgaagcag aaaataacta cagtactaat caattcacaa
    15601 gaacagcaag gatgttggaa gtctgatgcg atattgagat ctccaaattc taacgatcgg
    15661 aatcatgaaa acggtaaaaa tataccagtc tttaaggatc agatgaaaaa ttttactaca
    15721 gttacagttt tagatgcgtt gaacaaatat gcgctatctc ttattaaata aaaaagaata
    15781 aaagagttta aaagactttg ttggaataat taacgggata gcccaagctg gtttatccgt
    15841 aagtgaaaga tcattggtat ttggcacaag taaccaggag taagctttaa ccttgaattt
    15901 tatccgctct gtaaaatcta gttttagacc gataagtttt attttcttaa acaaattttc
    15961 ccggtcattt tttgctttca taaaagaaaa cagatgatat ttgatagctg gtttctcaga
    16021 taatggtatt ttgataccaa ctatttcttc taacgcatta acacctgacc aaagaaaagg
    16081 cgaaaattta taccgtttaa aacctgctgc tatctcctcc cagtttagat tcttaccaga
    16141 tttatcaata atacatgcta aatcaattaa atacttaaac ttcagtaaag gttctctgat
    16201 taagtgatga gaagcgatac acagaaaatc ataagttggt gataaggcca tacttattgt
    16261 tccattacta tcgtgagtta aatgtttggc taagaaatca tattcataaa atttaccaaa
    16321 ataattttcc actagtttcc attgtaattc tacagaacag tttatgccca atttatcttt
    16381 tggagactta agcgatagct cacgctgata ctttttcaaa aaaccaattt gatgttctga
    16441 gacatcgtaa gttgatataa aatcgtttga taaaaggcat tctctcaatt tactcaaatc
    16501 atcctttttg atcaggaagt ctatatcagc gctttccctc atagataatg atctataata
    16561 acggttggca aaccttacac ctttataatt aattactctt attccaagat tactaaattg
    16621 ttgacttaaa tggttaagta attgtaattg atatttaccg aacaatataa tacctacggt
    16681 atcttttttc aatgcattaa aaactgattg gtctatcgag atgtttgagg ttattacaat
    16741 ttcatagaca aaacctctga tatcatttaa ttgaaccagt ttatagaaca acaaccagtt
    16801 tatctcttcc ttttctaaga aatcgttcac ttctcccacg ctttgcttat caaaatataa
    16861 gcgtgttata agaattatca acgtttcctc atttccatat atcgttttga ggtgacctat
    16921 actaagcata tcttaccaag tctaaaactt atttgagtgt ttaacccatc gcatcttcca
    16981 atctatttga aaagctgctt caagatcatt ctcagaacaa ggaagacctt ttgtatcgga
    17041 tagtataact aaatcttcca tagtagaaat tttcgaagcc ttgtttttcg attccctaat
    17101 atctttaata acttttaatg cattctgaat tgacatttct tagacagatt aaaatgtaaa
    17161 acatccagat ttgagcccgg tttcttttcg taatttttct ccataagata aacctagctc
    17221 taacaaacta gctcctaaca acctaagcac ctgaaaaact aatcatccgc caaggcttcc
    17281 aaaattaact tagccgttgc gggatttgta gcaattggca cattatgcac atcgcagata
    17341 cgcatcaaca tttgtacatc tggttcatga gggtgtttgc ctagtgggtc tctgaaaaac
    17401 agaatgccat ctaacaaatc ttcggcggcc attgcagcaa tttgtgcatc gccaccgttt
    17461 ggtccgctca gttttttatt tacctgtaaa ccagtttgtt ccacatagcc accagtagtt
    17521 cctgtagcta ctagatccat tctcgataaa atctctaaat gatcttttac aaaaccaacc
    17581 atctctgctt ttttcccgtc gtgggctatc aatgcaattc tctttttcat ttgtttattt
    17641 aattgttttt aatggtaatg aagcaatcat atccccatgc actttgccaa aaccatgatg
    17701 gtttcattat ttaaaaaata tatatgcgat aaatatagcc gctaaaactc ctgctaactc
    17761 cgccaaaagc gcagcaggta aggcatgtct ggttttttta atggaaaccg aaccgaaata
    17821 aatagctaaa acataaaaag ttgtttccgt agaaccctgt attacacagg caacccgaga
    17881 agcaaaacta tcagcaccag tagtattcat caattccacc atcaacccac gggcaccact
    17941 cccgctcaaa ggtttcataa aggcaacagg caatgccgga acaaaacctg tatctaatcc
    18001 agcgaaagct accagatgtt ttatggcctc cactaaaaaa tctaaagcgc cagaacctct
    18061 aaacacacca accgcaacca aaatggccac caagtaaggg ataattttta cggcaatctc
    18121 aaacccttct ttggcacctt caataaatgt ttcaaataca ttgatttttc taaaaagtgc
    18181 cagaataata aacgacaaaa taatactgaa cagcaacaca ttgcccacca cactagaaac
    18241 aatactaatc tgatcttgcg atagcgtggt aaaataatat aatgttccgc caataactgc
    18301 ggccgcagaa cccaaataaa taaggatagt tttctggaaa agattgattt tttgataggt
    18361 cgctgtaacc actaatccca ctaaagtgga aaagaaagta gctaataagc aaggaacaaa
    18421 aacatctgac ggatctactg ctcctgccgc tttacgaaaa gccataatac tagtgggaat
    18481 taacactaaa ctcgatgcat taagcaccaa aaacataatt tgggcatttg aagcggtatc
    18541 tttttgcgga ttaatttctt gcagttcttt catcgccttt aaacctaaag gtgttgccgc
    18601 attatctaaa cccaacatat ttgccgaaaa gttcattaaa atagaaccca tagcagggtg
    18661 gttttttggg atctctggaa aaattttgct gaaaaacgga ccaacaagct tagcaaagat
    18721 attgatcatc cctccttttt cgccaatctt cataataccc aaccaaaacg tcattaaacc
    18781 aattaagcct aaggaaatct cggctccggt tttcgacata tcaaaggtgc tgtttacaat
    18841 ttcttgaaaa atctgataat cctgaaaaaa tatcagccta aataatgcaa ccccaaacga
    18901 gattatgaaa aaaccgaccc aaacgtaatt taatgccatg taaaattaaa tattgctaaa
    18961 ggttataatt ttttacaaaa taaaaacgca taaaatgttt ttgatgaata aaaaaatcaa
    19021 attaacctta tgcatcacaa ttaatcaaca attctctgtt aaggtttaat taaatcgaaa
    19081 ccccaatttt tgcctttctc ggttgctggt acacctttcc ccatccaaac aggcatcagc
    19141 gcacctttca aataatggtc aaaaaactgc tgttccctaa tagaaatatc tttacggttc
    19201 tggcgcttca tcaaattatg ttcgtcgcca ttataattaa gcatccaaac gggctttcct
    19261 aatctgcgca aagcagtaaa catttctatc ccttggtacc atggcacagc accatcgcca
    19321 tcattagcca taatcacaac aggggtttgc acatttggca ttctaaacaa tggagagttt
    19381 tcggtgtata attctggttt ctcccaaatt gttgcaccta ttctactttg cgttttttcg
    19441 tattgaaact gcctgttcat acctgtttgc caacgtatac cgccataagc agaaaacata
    19501 ttgaccaccg gtgcgcccga ccaggcagca gcatatttat cggttacggt tataaggtga
    19561 gcgacttgat aaccacccca gctttgccct tgtatgccaa ttttgttgcc gttaacccat
    19621 gagttttgtt ttaaatattc aacgcccgaa ttaataaatt cttcggcaga tttgccagga
    19681 tagccaatct cgtagctgat atctggcgta aaaaccaaat atccattgct tacaaaatat
    19741 gaaatattta atcgggatgg cgtgggcgct ggtgcttgat aggcaaatag cttgtccgac
    19801 actttttcat aaaaataaac aatcattggg tagctctttt taggatcaaa atcctctggc
    19861 ttatacaata ccccagtggc tttataacct ttcggagtta tccagttcac caacatggca
    19921 tttccccatt tataattggc ttgttgagga ttgatattgc ttaacttaag ttcgttttta
    19981 aaatttgtgc ttgcatacac atcaggagag ttttggtaat tttctttctg ataaaccatc
    20041 attttgctgt tctccgcttt aatgggttta gaaaaactat agttttccat caccaatttt
    20101 attggattac caggtttggc aatatctttt gtaaaccagc cgttttgctt agtaagctgg
    20161 ttaaaagcac ttaacaatag ttcacctttt tggggtaccg attttttttc tttatccaaa
    20221 gcagtgtagc gaaacgtggt tttgttttgc tggccgaaag cattggtcaa gttttttcca
    20281 atacctgttt cgggattaaa agaccagatg tcgtatttat cataaattaa aacctgtttt
    20341 tcatcttccg taaaacctcc ataattataa gatttggcat catcgggcac atcattttca
    20401 tcatcgccaa aaacactacc tttttcttgg ataatcttga tctttctatt tgttaaagcg
    20461 ctgtaagaaa accaattctg ttctttttca tcaaaccaaa gtacatgatt tcctttcgga
    20521 gaaaatttat attctgtttt ggtgttggaa ctaaccagtg tctttttacc agttttcaaa
    20581 ttaataagat aggctgttct taatgttgcg ccatcccact gcatcgcaac cctatttcca
    20641 aaatccgaag aaagcaaagc gaaatcttca tttccatctt ctggtaaatt aacagtgttt
    20701 agctcctcgg tgccaagctg taaaaactta ttgtttttta agtccaccat cgccaaaaaa
    20761 ctctccttta gctttttgct caaattggct aattgcatgg gttgcagata ttcatcctgg
    20821 tagttccaaa tgtctacttt cgcaacttca aaatcaacaa tggtggtatc cttagctaca
    20881 ggaatgggcg ctgttccaaa aaacacccga gaaccatctt tgctaaaaaa cactttcccg
    20941 ttttcactta catggttatt ttgtggcatg cccaccgttt ttgtagaaac caagatgctt
    21001 gcgctatcag tagtgaaatt ataaaaataa agatcatgag gctttaccaa agctttttcc
    21061 tcacttttat tacccgtaaa agctatttgt ttagttttct catcaaaagc gaaatttttg
    21121 tacaatccct taccaccggt taaaaatgta gttttcttac tgctagtttc aaaaaggtac
    21181 acgcctggtt ttacagaaga atcctttttt atccccgaac agctataaat taaatactgc
    21241 ccgtctttac tcagcaggta atcatttaca cctttaaatt tagcagaatc tttagttgcc
    21301 agatatttta aaactaaaac actaccttct ttagcctcgt tacttttctc tttctcgtct
    21361 gcaaaaaagt aagcagcatc ttgcaaactt tcagtctttt tagttttggt tgtgtccttt
    21421 ttttctttct ctaaaagata tgccaataca ttactggctt tatctggtaa tgcaaaagat
    21481 ttcacttgcg gtattttttc caacgttttg ctattcaggt ttaaaatacc caacgaatct
    21541 tttggcatat ccaccgcttt ctttttcttg attttagcct gtctggtatc agaaaattta
    21601 ggaataatag aaaaaaccac aaaagcctcg tcttgagtaa ttgtaaattt ttgtgcgtgt
    21661 ggataagaaa aaacagttga tccatttttt accgacttaa tcaataaagt ggtatcacct
    21721 gcctgtggcg caatggaata gccaatccat ttaccgctgg cactaatttg tttacttcct
    21781 atactttccc aagaatcata aacgctgtgg tctaccggtt ttttttgaga aaagcaaaca
    21841 aacgtagtac aggtaaatag gagaacgaga aatgttttag tttttaagaa aggtatatta
    21901 aatttcattt ggttgttttt tcgatggttt tatttgattt tggatcaata cgtatttcgt
    21961 aatctcagaa actaatttta acggcaattc cttattgatt gggaactgaa cagcaccttt
    22021 agaatgcttg aatgccaata tcttactttt aaacttaatt aacgcatttg gacctggata
    22081 aaaacctata tgctttttgt agcctgcaaa atgaaccaga ttcacatcca ccctataagt
    22141 tggtatccca taactaatta cctctacagc atctggaatt tccaaaatta ttgtcgctct
    22201 taataagcgt aataagtttt gcatttctgt aggaaactgt gcgatatatt cgtcaactga
    22261 aaatattttt tgttgcattg gtatcaaaac tgaattatta aaccctaatc ttttataaat
    22321 ctattattat tttttttctt tgactatttg tgactaatta aattatattt gaaaatcaca
    22381 ataaaacagg ccttttggta aatttttaat acagaatgaa tcaaatcata aacaatattg
    22441 aacaatttga agcggttata ggtttagaag ttcatgttca attatctacc gcatcaaaag
    22501 cattttgttc agattcagca actttcggta atttaccaaa tcaaaatata agtcccgttt
    22561 ctttaggttt accgggcgca ttgcctttaa ccaatgaaaa agcggtaaag tatgccacca
    22621 aattaggttt ggctatcgac agtaaaatca accagtataa tttcttcgac cgtaaaaact
    22681 atttttatgc cgatttgcct aaaggctatc aaattacgca agataacgag cctatttgta
    22741 tcggtggaaa actcaaaata aggttagaaa ctggtgagga aaaagatatt attctaaatc
    22801 ggatccacat ggaagaagat gctggtaaaa gtatccatga tttagatgca gattattctt
    22861 atatcgattt aaaccgagct ggagtagctt tgttagaggt tgttacagag cccatgatca
    22921 gttctggcga agaagctgcc gcatacctaa cggagttgcg taaattagtt cgttaccttg
    22981 atatttgcga tggcaacatg gaagaaggct ctatgcgctg cgatgccaat gtttctgttc
    23041 ggttaaaagg tgaaactaaa ctagggaacc gttgcgaggt taaaaaccta aactcgatca
    23101 aaaatgttca gcgagcaatt gagcatgaaa tccaacgtca gatcggttta attaataaag
    23161 gaaaaaccat tgatcaaaat accttgaatt ttgatgcagc aactggcaaa accacgcctt
    23221 tgcgttctaa agaaatggct aacgattacc gttatttccc cgaaccagat ttattgccaa
    23281 tggtgatttc tgatgagtat ttggaggcaa taaaagcaga aatgcccgct ttgcccgaac
    23341 aactttatca gcaattcacc aaagaaatgg gtttacccag ctatgatgcc ttggtgctta
    23401 ccgctgataa agccatggca gattatttta tagcaataac aaagcacagt acaagttata
    23461 aattggcatc taactgggta atgggtacgc ttaaatcatt tttaaacgaa acacaacaag
    23521 gttttgctga tttgagaatc cctgccgaag aaattgctgc tatcatcaat ttggtagcgc
    23581 ataaagagat caacaatagc caggcgaaaa acaaattgtt tgcggccttg gttctgcaac
    23641 cagaagctaa agttgccaat ttggttgagg aactaaatct gatccataaa aaatgtgaca
    23701 atgaattaga gggatttatc ataacagcgt tagaaaaatt cccagataag gttaaagaat
    23761 accagaacgg taaaaaagga gttataggac tgtttatggg cgaagtgatg aaattatctc
    23821 atggtaaagt agaccctaaa caggcaaata agttaattat cgaaaaatta gaaggtatta
    23881 aatgaatcca tcctgatttt gcagaagctc ataagctatt gctaatcaag tcatgatgga
    23941 ttcatcaccc ttaaaaaata aaataaatag atgaaaaagc attttattgt aggattattt
    24001 ggagtagcgc tgtttgcagt ttcatgttca aataaaagtg agtttagcat taaaggttcg
    24061 tttacaaaca ttggcgatgc caaaaaggtt tatttattag aactagatac ttttggacaa
    24121 atgattccaa ttgactccac ttttttaaat gaggacaagc aatttacttt aaaatccaaa
    24181 agtgtagatc cagagtttta tcaagtggca gttggccaaa gagcgttttt tgtgattgcc
    24241 gaaaatggcg acgaagttga gcttaaagct gatttgaaca acccaactgg aagttacgag
    24301 atcaagggtt ctgaggaagc agataaaatc accgaataca ataaaattac cgcagtatac
    24361 agtcaacaaa atggagcttt agccgaacag tatagcaaaa tgattacggc taatcaagaa
    24421 aataaagacc agattattgc agagtacaat gcaaaagcag gggttatagc taagccattt
    24481 ttagagcaat caatggaatt catcgaaaaa aataaaaaat cgatgactgc attttttgcg
    24541 gcaaatatca tgatgggcat gcaacatgac gattatgaaa gtaaactgat tgcttatagt
    24601 aaagaagcag cggaaacatt cccaaaaaac actgcgatca catcttttgc aaaacaaatg
    24661 gaagctacaa aaaaagtagc tgttggaagt gttgcgccaa caatttcggc tttaagcaca
    24721 aacggaaaag ttatcaacct agccgatttt aaaggcaaat atgtcttagt agatttttgg
    24781 gcatcttggt gcgcaccgtg tcgtcaagaa aacccaaatt tagttgctac ataccaccgc
    24841 tttaaagata aaaattttac ggtgttgggt ttttctttgg atgataacga agatgcgtgg
    24901 aagaaagcaa ttattaccga taagttagat tgggcacaag tttcggaact gagacaatgg
    24961 gactctccta ctgctttgtc ttataacgta agcgcaattc ctgcttcttt tgtaattgac
    25021 ccaagcggaa aaattatagc taagaatttg cgtggagaac aacttaatca gtttttagag
    25081 aaaacacttt aagcattttt tacctattta attacgtaaa ttggctataa gtttaatcat
    25141 ctgttaatat taacttaaca atgccggtaa aaaagcatgt agattcgtaa caaatagatt
    25201 ttatgattag taacaaacaa aaaattctta ttgttgatga cgaaccagac attctggaac
    25261 tgattgctta tagcctaaaa aaagcaggtt acaccatttt caccgctaaa aacggaaaag
    25321 aagctgttca agaagcaaaa aaatgccttc cagatttaat cattttagat gtgatgatgc
    25381 cgaaaatgga cggtattgaa gcttgtaggg ttttaagaac aatgcctgaa tttaaaaaca
    25441 ccttcatggt ttttttgact gccagaagtg aagaatactc tgaaattgct ggttttaacg
    25501 ttggtgctga tgattatatc gcaaaaccta ttaaacctag ggccttacta agcaggatta
    25561 acgctatttt aagacgtaac ttacaagcag aagaagttac agaaacaaaa ctggaaattt
    25621 ctaatttggt aattgataga gaagcttttt tagtatttca agacggcaat aagatagtac
    25681 tcgcaaaaaa agagtttgaa ttgttatact tattagcatc aaaacctggt aaagtatata
    25741 cccgcgaagc tattttaagc agtatttggg a
//
