LOCUS       NZ_JH792251            23535 bp    DNA     linear   CON 15-MAR-2024
DEFINITION  Bacillus mycoides strain VD078 supercont1.1, whole genome shotgun
            sequence.
ACCESSION   NZ_JH792251
VERSION     NZ_JH792251.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5172041)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A., Chapman,S.B., Goldberg,J.,
            Griggs,A., Gujja,S., Hansen,M., Howarth,C., Imamovic,A., Larimer,J.,
            McCowen,C., Montmayeur,A., Murphy,C., Neiman,D., Pearson,M.,
            Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P., Sykes,S.,
            Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Bacillus cereus VD078
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5172041)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A., Chapman,S.B., Goldberg,J.,
            Griggs,A., Gujja,S., Hansen,M., Howarth,C., Imamovic,A., Larimer,J.,
            McCowen,C., Montmayeur,A., Murphy,C., Neiman,D., Pearson,M.,
            Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P., Sykes,S.,
            Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000290895.1
            Current Name                      :: Bacillus mycoides
            Previous Name                     :: Bacillus cereus VD078
            Date Updated                      :: 2018-06-08
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_000003925.1
            A1 Name                           :: Bacillus mycoides
            A1 ANI                            :: 98.66715%
            A1 Query Coverage                 :: 80.95%
            A1 Subject Coverage               :: 88.35%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_002014665.1
            A2 Name                           :: Bacillus cereus VD078
            A2 ANI                            :: 89.90313%
            A2 Query Coverage                 :: 68.38%
            A2 Subject Coverage               :: 77.02%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R38749
            Assembly Name                     :: Baci_cere_VD078_V1
            Genome Coverage                   :: 146.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000290895.1-RS_2024_03_15
            Annotation Date                   :: 03/15/2024 02:24:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,225
            CDSs (total)                      :: 6,127
            Genes (coding)                    :: 5,875
            CDSs (with protein)               :: 5,875
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 252
            CDSs (without protein)            :: 252
            Pseudo Genes (ambiguous residues) :: 0 of 252
            Pseudo Genes (frameshifted)       :: 92 of 252
            Pseudo Genes (incomplete)         :: 158 of 252
            Pseudo Genes (internal stop)      :: 71 of 252
            Pseudo Genes (multiple problems)  :: 58 of 252
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:24:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4012485
            Orig. end                         :: 4036020
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JH792251.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The organism was changed from 'Bacillus cereus VD078' to 'Bacillus
            mycoides' in June 2018.
FEATURES             Location/Qualifiers
     region          1..23535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="11"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13535](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13535
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    570..586
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            complement(601..1146)
                     /locus_tag="III_RS20220"
                     /old_locus_tag="III_04095"
     CDS             complement(601..1146)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="III_RS20220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04095"
                     /product="hypothetical protein"
                     /protein_id="WP_002168863.1"
                     /transl_table=11
                     /translation="MRWKAGTFEKIETNDSYVEKIINTFKEQNLNGGAIISCFKVHNEN
                     FFKEIPHSKDGYEHFFRRIFNSLDIIHNLEELKIHTSEKYKFHFKEHLVVMLDGSIAAQ
                     ILWGGAYEGFKERPVIAKQLAVNVCQYMFQDRYEDIKVFESYRPWTDWFYDVAWDATWM
                     VLDSKEHKMWLVCATDTD"
     gene            complement(1227..1496)
                     /locus_tag="III_RS20225"
                     /old_locus_tag="III_04096"
     CDS             complement(1227..1496)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126037.1"
                     /locus_tag="III_RS20225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04096"
                     /product="hypothetical protein"
                     /protein_id="WP_002126037.1"
                     /transl_table=11
                     /translation="MQRVTSYPWSLRKIFVFFLCFILPPIGAIYILMNREALQKRDYIL
                     YLLFAAINISLWLSLMIFDRSMWMVAGHDVLGVIVIIFSNMNKS"
     gene            complement(1513..1875)
                     /locus_tag="III_RS34060"
                     /pseudo=""
     CDS             complement(1513..1875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034130.1"
                     /locus_tag="III_RS34060"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKKAIFFLLTCLLLIASITYIICNK"
     gene            complement(2010..2192)
                     /locus_tag="III_RS20235"
                     /old_locus_tag="III_04097"
     CDS             complement(2010..2192)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="III_RS20235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04097"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_002086895.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGLVLFLAVFLFIRKDVQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLINQSL"
     gene            complement(2221..2598)
                     /locus_tag="III_RS20240"
                     /old_locus_tag="III_04098"
     CDS             complement(2221..2598)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="III_RS20240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04098"
                     /product="hypothetical protein"
                     /protein_id="WP_002168864.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGIIFLIMSGTMILAGIMTHSAPPIPTYTVLAMMI
                     MCFCLSYLHPQFKEKDERMKLIRYKGMFVTFFALTAYYLLFSIGLNLKIITLSATELLN
                     ILMALTMSTVFISFVVLSKRY"
     gene            complement(2595..2810)
                     /locus_tag="III_RS20245"
                     /old_locus_tag="III_04099"
     CDS             complement(2595..2810)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428504.1"
                     /locus_tag="III_RS20245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04099"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_002168865.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKLGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKAFQTTIEHVFIYEGKEEGEKG"
     misc_feature    complement(2992..3006)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     misc_feature    complement(3038..3058)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 30.06"
                     /tool="antismash"
     gene            3706..6573
                     /gene="odhA"
                     /locus_tag="III_RS20250"
                     /old_locus_tag="III_04100"
     CDS             3706..6573
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="III_RS20250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04100"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_002168866.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLIEKTMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFIGQKRFSIEGV
                     DMLVPVLDEIVSEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYNHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTTKSFVILVHGDAAFPGQGVVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQSAGVLNADEVETITQFIQEELKAEYA
                     QVPPADTSAATIHVKVPEVVAKGIQPIDTGVSIESLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVIMTPKSLLRHPLTLSTGSELSEGRFQPALEQGNLGA
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHMVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVFSN"
     gene            6703..7959
                     /gene="odhB"
                     /locus_tag="III_RS20255"
                     /old_locus_tag="III_04101"
     CDS             6703..7959
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="III_RS20255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04101"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_002168867.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESISEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAAVEVSTPAPANEQPKQETTEAPKA
                     AAPSAEQNKALQGLPNTNRPIASPAARKMARELGIDLNEVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKQSPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDM
                     SAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYDI
                     GIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGLKARDNKLSLKELQGGTFTITNGGV
                     FGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAVS
                     FLVAVKDMLEDPKSLLLEG"
     aSDomain        8085..8384
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_III_RS20260_Heterocycloanthracin_C_RR
                     E.1"
                     /evalue="3.40E-57"
                     /identifier="RREFam011.1"
                     /label="III_RS20260"
                     /locus_tag="III_RS20260"
                     /protein_end="100"
                     /protein_start="0"
                     /score="181.4"
                     /tool="antismash"
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNS"
     gene            8085..10004
                     /locus_tag="III_RS20260"
                     /old_locus_tag="III_04102"
     CDS             8085..10004
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="III_RS20260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04102"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_002168868.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1164.0,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     6.3e-55, bitscore: 181.4, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 2.8e-11,
                     bitscore: 41.5, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFETYRAANVLIIGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     AETNYDRIHELSERAYANDDNVLIQEIDITIDRPLHEVFEPFDWILYVSQNGDIESLRA
                     IHTICREFKKNFIPAICLSRIGLAGPVVTADREECWESAWHRLHETTLQSENPPELFSP
                     IASAMLANVIVFELFKHVAEGSHRQHNPQFFLLNLETLEGKWHPFIKHLLATDEIFTID
                     TVQNLQENLAQRSGQYTSTELFRFFDTLTSKEAGIFHMWDEQDLHQLPLSQCNIQVANP
                     LSDGPTSPLPTITCGGLTHNEARREAGLTGVETYVAEMIHRLIPEHTDIGIGAGETMTE
                     GVYRALQKHLNNKLYERQSHMLEEITELYLTEIHDKHCRFYYDALSTIHEIPKVGMSEE
                     LLGFPVVWIGINDRWYGAANINITLALRNALQQALLHIQNEEIPYKANMLPESSIVLYS
                     TDPVRVAIQEEEEIPGVQSLQVALQNLTENNLYPFVFDLAIESFLRDNLDGVYGVLIAK
                     EDDQ"
     aSDomain        8112..8351
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_III_RS20260_Thiopeptide_F_RRE.1"
                     /evalue="1.50E-13"
                     /identifier="RREFam004.1"
                     /label="III_RS20260"
                     /locus_tag="III_RS20260"
                     /protein_end="89"
                     /protein_start="9"
                     /score="41.5"
                     /tool="antismash"
                     /translation="LKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDWIEKLMPMFN
                     GNHSLTEITDGLPLPYQNRVFEIGEILYENGFIRD"
     gene            10001..11950
                     /locus_tag="III_RS20265"
                     /old_locus_tag="III_04103"
     CDS             10001..11950
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="III_RS20265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04103"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_002168869.1"
                     /sec_met_domain="YcaO (E-value: 2.3e-83, bitscore: 278.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-136, bitscore:
                     453.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLTDYVHEQLCKQYSLIRQHTITEALPENIHLAL
                     VLHDGSPSSVHRDAELIFRSNNIPWLRAFTSFGEGIIGPYVKPLTTGCSHCADGRRFIA
                     GFDQKEMWELQRKYALKAENVTRRDVRATQNGMLQMCQLIHAETEKILAHGYSSLENEL
                     ILLDLQTLKCTRNSFLPDPLCPVCSNLPDDTADAAQISLQPSLKTSTETYRCRSIHELN
                     TFLTRDYLDYRTGILNGKMQHSLLPFADVIINMPLLFGNEGVAGRTHSFSLSKATAILE
                     GLERYCGMSPRGKKTNVHGSFRELEDIALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLLQSRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMLERLRTITGYELYVFNATMEHGIPSIWVIAK
                     NTRQDGMNLVCAGGAHMEPIRAVKNAIHEIAGMLLITDEELEQKREKYENGLQDPYLVS
                     QMEDHSMLYGLKEAEERLHFLLRDDAPVQTFQEMNALQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVNQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYWAEP
                     LTNESLNPHPHPFP"
     gene            11973..13535
                     /locus_tag="III_RS20270"
                     /old_locus_tag="III_04104"
     CDS             11973..13535
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135039.1"
                     /locus_tag="III_RS20270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04104"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_002168870.1"
                     /sec_met_domain="PF00881 (E-value: 8.3e-10, bitscore: 37.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPDTFLHHLHFSINEIMSSDKEIDWEDAPLPYKLYRNLPVIPLS
                     LEIPLTLRNSSTKPNLEEIGHYLWYSFGLTQLCQPTTNLENNKTTTLFRRFIPSGGALY
                     PNELYMYLKIDHYPDGIYHYDAAHHRLILLREGNFDSYLTEALGNRCNIHSCFGAAFVS
                     TMFWKNFFKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRAMNHLLGLSE
                     GEESVYAVIPLSTEPNTDWFHDDHHENKTITSHDLLQQILPLTHEHFVRSKYVDEYPMI
                     KKINAASMIESTEHFQTFTREERQQYSAHAMQLPKVERLSYDFLQLCKKRYSPDSDFIL
                     TKWDAAELATLLQAASLSFPYYNDLDGKYLNENARVSLYGCFYNVKDIENGAYAYNSRT
                     HSIQPIRYGDLRYSLQSSMTMDNVNLFQVPLCLHVIGNKDYYKNKLGYRGYRIHQMEAG
                     MLVHKLVLAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQIPVGAYRARNWLKGS
                     LHN"
     gene            13628..14218
                     /locus_tag="III_RS20275"
                     /old_locus_tag="III_04105"
     CDS             13628..14218
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 6.4e-15. Score:
                     46.0. Matches aSDomain: nrpspksdomains_III_RS20275_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158829.1"
                     /locus_tag="III_RS20275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04105"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_002168871.1"
                     /transl_table=11
                     /translation="MSILQRLIEQAKNPHGTIGSSMLCIMNAAHTRLTNWALQKIHIRE
                     NAVILDIGCGGGKTIQTLSNRTPLGKIYGIDYSNQAVENSKKANMKDIKAAKVIIHQAS
                     VSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLLVAETFKIQYHMDTF
                     KTTEELVNLFYETGFTSVKCYEERGCLCLIGNK"
     aSDomain        13772..14074
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_III_RS20275_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.40E-15"
                     /label="III_RS20275_oMT.1"
                     /locus_tag="III_RS20275"
                     /protein_end="149"
                     /protein_start="48"
                     /score="46.0"
                     /tool="antismash"
                     /translation="ILDIGCGGGKTIQTLSNRTPLGKIYGIDYSNQAVENSKKANMKDI
                     KAAKVIIHQASVSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLL"
     gene            complement(14250..14660)
                     /locus_tag="III_RS20280"
                     /old_locus_tag="III_04106"
     CDS             complement(14250..14660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="III_RS20280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04106"
                     /product="DUF3908 family protein"
                     /protein_id="WP_002030461.1"
                     /transl_table=11
                     /translation="MAINMNTIEEWIAESNARNEEDLGNVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGEEKEEYIEIEKLKYDDITNSNLKTNDKNTTLELKFS
                     NGKAINLDSLNDNYGTKNWLFARQIKSIFKVI"
     gene            complement(14820..16154)
                     /locus_tag="III_RS20285"
                     /old_locus_tag="III_04107"
     CDS             complement(14820..16154)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="III_RS20285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04107"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_002168872.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3e-61, bitscore:
                     205.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGVIASTEKLIARDVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAVHMKTKDVFEFS
                     YDRLLIATGVRPVMPDWEGKDLEGVHLLKTIPDAERIVGALQTNSVEHVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGKER
                     VEQLETDKGTYKTDLVLVSVGVQSNTDFLEGTNIRKNHKGAIEVNAYMQTNVKDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMVDKRRAFKGTLGTGIIKFMNLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPSASPLHLKLLYHADTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            16353..16781
                     /locus_tag="III_RS33310"
                     /old_locus_tag="III_04108"
     CDS             16353..16781
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016088839.1"
                     /locus_tag="III_RS33310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04108"
                     /product="hypothetical protein"
                     /protein_id="WP_002168873.1"
                     /transl_table=11
                     /translation="MCPGLLAQTPEEPQEPKAATPLDQEFSINATIYSARAWLSDNDTY
                     AQDIWKGTRFASASHAGKSIFPSGTIKVINLSSDTITVTTSGEADHTLKTVVPPHSEVA
                     LSPSSLSAVQASTSGKASKVTFLFHIFFSRDPGPAKQP"
     gene            complement(16822..18060)
                     /locus_tag="III_RS20295"
                     /old_locus_tag="III_04109"
     CDS             complement(16822..18060)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="III_RS20295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04109"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_002168874.1"
                     /transl_table=11
                     /translation="MNVCTKCGIHFEDGVQFCQNCGTKRGNPLVKKQKMSKGTIIGITL
                     LTFFIIVLGGLYAYGSSYYSQSSQVERIITVLQERDGEKLAEIVTTDDPAVIVTRESVT
                     PLFSYIKENPSYVNELKEYLRQGEKQGDGIERADFSLTKDGKYFVLFDRYKLKAKTYYT
                     TLLTNEKGTSLKLNGKEIDKTNDKKFDKQYGPFLPGTQVFQAEYKNDYVKLLREEKVVL
                     MKQSQNNVTIDLTLQGQYITVQTNAPGATLYVNQKPVTVLTGEEITWGPIATDGSAAIY
                     LERNGESGRETTKVETVTALSAYNLPFQKKSVEKTVVYNVTPPPATGYVYNGFIFPDSD
                     IRKLTSAELTYLSKEQLKIARNEIYARHGHMFQTKDMQAYFSKQSWYRENPYFTGTLTS
                     VESYNVELIKSRE"
     gene            complement(18080..18862)
                     /locus_tag="III_RS20300"
                     /old_locus_tag="III_04110"
     CDS             complement(18080..18862)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158836.1"
                     /locus_tag="III_RS20300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04110"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_002168875.1"
                     /transl_table=11
                     /translation="MKCPACNTENAAEARFCGNCGHSLTEEVVASGGQEEGQLSRPARV
                     KETRPNETVEQAKQFASGYFQFFKNAFKSPSAIMESGNIEVRNGIASLVLICFLGACIF
                     YRMMSAAATVTRTLVPDIATPTFFGESVMVFFFLLILTLFVGFIIFVSGKMMKSSFSFL
                     EAFGIWGTIATPAIAILVLSFLFSFLLIFFLPILLWIATTYMVISIIVAILKLDNGGLD
                     PVYTLLIANVLIGIATFIVFWSYINTIIQTFTQGLTGF"
     gene            19063..19896
                     /locus_tag="III_RS20305"
                     /old_locus_tag="III_04111"
     CDS             19063..19896
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="III_RS20305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04111"
                     /product="hypothetical protein"
                     /protein_id="WP_002168876.1"
                     /transl_table=11
                     /translation="MEFVNSIFQTLLTSVIQLFSLIGVIIVIGFILGYLESLTRTYWSR
                     AFGRKGFLLTAWIGVPVHELGHAIMCLVFRHKIVATQFFPTDTSQGALGYVQHQYNQKS
                     IYQRIGNFFIGIGPIISGITALILLMRYFVPESYSLFNTTLETTIAATSINLEMIQNMF
                     LSTFFLLKSLFTMSNLLTPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIMLFLF
                     NLIAGLFQYDSNQLIGKMMKYNMYLIAFSSVALLFSCISTLVSFGFYKMRGGRSL"
     gene            complement(19942..20913)
                     /locus_tag="III_RS20310"
                     /old_locus_tag="III_04112"
     CDS             complement(19942..20913)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029762.1"
                     /locus_tag="III_RS20310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04112"
                     /product="DUF4179 domain-containing protein"
                     /protein_id="WP_002168877.1"
                     /transl_table=11
                     /translation="MSIYKELNDIQLDITEFEETPLTKIEEKQWEKRVKNKLRKNKKTK
                     KWFGVAAACMLIVSITVPLGQTSLANMPFIAGLIEKYIDKQQPLDYSPYKTAIGKTAEN
                     KYGKLTLNEVLVDDNKLFISSTFEPAKGVKFDYQTYLIPQVRINGRDFSNTKDAQSIAV
                     NDSMFTIYGGIELSEIPQTDALQIEITYDTFNRDTVIEQPWIFAIEVSQAQLMKEKRTF
                     DLNETIALYDGNKVTVNKVVSTPISTTIYYDVTQSTNEDIYFKIESESGEAHTFKEVVI
                     SNEDGGISFSRFDGINVAVGKYSLVPYSGKENKKIGPPIPIQ"
     gene            complement(20918..21463)
                     /locus_tag="III_RS20315"
                     /old_locus_tag="III_04113"
     CDS             complement(20918..21463)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002186397.1"
                     /locus_tag="III_RS20315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04113"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_002168878.1"
                     /transl_table=11
                     /translation="MKITEENVVQQIKKRNEKSVTFIIQTYGGLLSVIIKRYVQSNQQD
                     YEECLDDVLLAIWFHIDSFDSSKNTFKQWIAAIAKYRAIDYQRKNARNQQQTVCVCTEI
                     NDRLYQEQRKQNDFLDVQELLSELSATERNIFEKYYLEGVPSREIASHLNVKESWIHNK
                     LSRGRKKLKQIFIFKNGV"
     misc_feature    21505..21523
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.03"
                     /tool="antismash"
     gene            complement(21622..22314)
                     /locus_tag="III_RS20320"
                     /old_locus_tag="III_04114"
     CDS             complement(21622..22314)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002027272.1"
                     /locus_tag="III_RS20320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_04114"
                     /product="YukJ family protein"
                     /protein_id="WP_204100998.1"
                     /transl_table=11
                     /translation="MKEMPLKNYGVLKGTVVQSKIGKGKTPHYQVHLQGEAEVDYRIAI
                     NVKSQSYPSEVLYFASEHIDSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQM
                     IPLPAEKTGSDNDLNEKIERYIKRAIDEKAIIYAFGERWGPEEKVPDSYFHFTPGNGIH
                     DIHMNQGNVEKWQGDDGKWQDGGILIHFEKKEEWIGIFLAFQSQSWCTDEEGHARVPVE
                     HCDYKRNN"
ORIGIN
        1 gtttttgacg atagttgatg tcattgtttt ttcgattgct ttttcagatt gttctttgtc
       61 ttcactaaaa gcactagcga aggccattgg cataacttct cccactgctt ttgttacagc
      121 aacggataga tcagcagatg taattttcac tttcacttct gctttgtcat cctttttcga
      181 cacttcttct ggcttttcaa atttaaagtt tttcgtaatt gcactcagca ttgcttttgc
      241 ctcagcatca tctgtttttt catttagttt attaaattcc ttgtcactct caacaaatgt
      301 acgagccttt tctacatcac ctttttgtat cgctgttaaa aattcttctg tagtatcttt
      361 cggatttgca caccctgcta aaacacctac tgttaatcct aataccatca ttaacagcaa
      421 taatttctgt atctttttca cgttcattct cctcttatct tttctagtaa gtcagcatta
      481 tacaatagta tgaaactgac attacaaaca ttttttagta tagcatttat atgattcgtt
      541 ttctattcat tcccaaaaga taaagggcct tgtagcattt ctacaaagcc ccctcttcta
      601 tcaatccgta tccgtagcac aaactaacca cattttatgc tccttactat ctaacaccat
      661 ccaagtagca tcccacgcaa catcgtaaaa ccaatctgtc caagggcgat agctttcgaa
      721 cactttaata tcttcgtatc gatcttggaa catatattga catacattga ccgctaattg
      781 ttttgcgata actggtcgtt ccttaaatcc ttcatatgct ccgccccaca aaatttgagc
      841 ggcaatgcta ccatcaagca tgactaccag atgttcttta aaatgaaatt tatatttttc
      901 tgatgtatgt atttttaact cttctaagtt atgtattata tctaaagagt tgaagattct
      961 tctaaagaag tgctcgtatc catctttcga atgtggtatt tctttgaaaa aattttcgtt
     1021 atgtacttta aaacagctta ttattgcgcc accatttaag ttttgttcct taaacgtgtt
     1081 tataattttc tcaacatatg agtcattcgt ttctattttt tcaaacgttc ctgctttcca
     1141 tctcataaca tcactactct ctattaaaaa tttgtttctt cattataaat agcaaaataa
     1201 aacccagcaa ctttaagatt gctgggttag ctcttattca tattcgaaaa aataataaca
     1261 attacaccaa gcacatcatg ccccgctacc atccacatac tcctatcaaa aatcatcaat
     1321 gataaccaaa gcgatatatt aatagcagca aataataaat ataaaatgta gtctctcttt
     1381 tgtagcgcct ctctattcat caaaatgtaa atggcaccga taggaggcag aataaagcaa
     1441 aggaaaaaga caaatatttt tcttaacgac cacggatatg aagttactct ctgcatatga
     1501 gtctcctttt cattatagta cttgttttaa catcggcctt gctactctat attcttcact
     1561 agtaggttct tttacgagta taggtggcct ttcatcctct tcttctaaaa ttatttcaaa
     1621 tacttctgtt ttttcttcta atacgttgga ttcactatct ttagtaggct gtttgcttgt
     1681 ttcaattttc ttcgtcactt ctccaagttt ttgcccggct tcttctgctt tggcaggttc
     1741 attcgtaacg tagtattcat gcccctccta tactaatata ggtggaactt gttctcattt
     1801 gttacatatt atataagtaa tactagctat aagtagtaga catgttaata aaaagaagat
     1861 agctttttta ttcatatact attctcctta tctatcattt tattggatta tataatacaa
     1921 gatatagata gcaaatagat tttatggtaa tttttagttt tattttcaaa aagaaaaacc
     1981 ttacaaaagt aaggttccat ttttaaattc tatagtgact gatttattaa aacgatcatt
     2041 acgataatcg ctataaacat aacaactaag cagccgatca ttttataaaa tcctcgtttc
     2101 gttaacgttc cgccctgaac gtctttacga ataaataaga ataccgctaa aaataataca
     2161 agccccatgc caaaagcata catcatttgc atatgttaat cttcctttct cttttacatc
     2221 ttaatatctt ttcgataaaa caacaaacga tataaaaact gtactcatcg tgagtgccat
     2281 aagtatgttc aatagttcag tagcagatag tgtaattatt tttaagttta agccgataga
     2341 gaaaagaaga taatatgcgg ttagtgcaaa aaaggtcacg aacatccctt tataacgaat
     2401 aagcttcatt cgctcgtctt tttctttaaa ttgcgggtgt aagtaactta agcaaaaaca
     2461 cataatcatc attgcaagta ctgtataggt tggaattggc ggtgcagaat gcgtcattat
     2521 acctgctaat atcatagttc cgctcataat taaaaagata atccccataa ttacaaagta
     2581 cttttgtgaa taattcatcc tttctccccc tcttcttttc cttcataaat aaatacatgt
     2641 tctatcgttg tctgaaatgc ttttgcaatt tcaaatgcta atggaagtga tggatcatat
     2701 ttcccttttt caattgagat aatggtttgt ctggaaactc caagtttctc agccaatttt
     2761 tcttgagata gtccaagttt ttttcgatat tcgaccattt tattttccaa ggaaatttct
     2821 ccctccttcc ttataccgag tatatacgta aaggaaactt tacgtcaagg ttcctttaca
     2881 ttcatttcgt ctatttttca ttctatttat cccgattgat gagggctaat aattagtgga
     2941 ggatggacac cccccccact gattaaagtt tcactttata tagaagaaac tttttcaaat
     3001 tcagcacgtc tattttgaaa tgaaacatgg aacaatgtat atagccgtta ctatatctcc
     3061 tctccgtttt tatgaaaatt taatatctcc atatttgttt tatcctttta aaatgtttca
     3121 ttctgctctt tatcgggtga aatgcgctat tgtttttacg ttgtttttcg ccatatttat
     3181 agaaactaac ggtttatgaa gcatttttta tgtatagcca ctttttttgt agaaatcctt
     3241 cattttcctt tcgatattta acactatcga gataaagttt atggtaaatt cataattttt
     3301 tattttttat actatattcc gttatattgt tgtataatat caatgaaagc gcttattatt
     3361 ccaatataca taattcgaac tacgttttat cgaaacattc tgatagttat acttatattt
     3421 aaatgcaaca attataggta ttaatgtagg tataccaaat atatccaccc cattttcccg
     3481 tgaaattact ttataacatg aaagattaac ttgggtgata agttattgtg aatgtttttt
     3541 tacaaaacag ataagtaata gtgtttggta ttatgtaaat tattgtaata acataagagt
     3601 aaagaaaaac atttacattg attattggtt catcaattat tgaaaagagc aaaatgcacc
     3661 tttttgtatg gaaaaaggat tatatgcatt gggaggttta aacaaatgac gaggaagaat
     3721 acaacgacaa acccttgggc caagttccat ggtccgaacc ttggttatgt tattgaacag
     3781 tatgatcttt acgtaactgg agcaggttct gttgatccgg aattacaaga gctttttgaa
     3841 atttttggag ctccttcgtt tcaagatgat gtcgtaacag gggacaacac agcaacacat
     3901 ttttctcctc aaaacacagg gaacattgaa aagattctta aagtcgttca acttgttgaa
     3961 cagattcgtt ctttcgggca tacattggct cacattaatc cgatggaaga tgctgcaaac
     4021 ggacaatctc ttatcgagaa aacaatgaac gaactgagcg atgctgactt gaaagcgatt
     4081 ccagcaaaaa cagtatggca agatgcacca gagggtattc acactgcact tgatgtaatt
     4141 catagattaa aagacgttta tacaaaatct ttagcttatg aattctcaca tatacaagat
     4201 agtgaagaac gcgcgtggtt gcatcaaatg gtggaatcaa attcattgcg tcaaccatta
     4261 tcaaataaaa aacgaactgc tcttttaaaa cgtttaactg ctgttgaagg tttcgagcaa
     4321 ttcttgcata aaacattcat tggtcaaaaa cgtttctcaa tagagggcgt tgatatgctt
     4381 gtacctgtac tagatgaaat tgtttcagaa ggtgctaaag gcggcgttga agatgtcatg
     4441 attggtatgg ctcaccgtgg tcgtctaagc gtactcgctc acgtattaga aaagccatat
     4501 aatcacatgt ttgcagaatt caaacatgca aaaatagaag gtgcagtggc aaatgctggc
     4561 tggactggcg acgtgaaata ccatttaggt agagaacaag tcgttggtaa tgaagaggtt
     4621 agcacccgtg ttacattagc aaataatccg agtcatcttg agttcgttaa ccctgttgtt
     4681 gaaggtttcg cacgtgcagc tcaagagaat cgtaaaaaat ctggtcttcc agaacaagat
     4741 actacaaaat cattcgtaat tttagttcat ggtgatgctg cattccctgg tcaaggtgtt
     4801 gtgtctgaga cactcaactt aagtagattg aatgcatacc aaactggcgg aactattcat
     4861 gttatcgcaa ataatgcagt cggctttacg actgatagct atgattctcg ttctactaaa
     4921 tattcaagcg accttgcaaa aggtttcgat attccgattg ttcacgtgaa tgctgatgat
     4981 ccggaagctt gtcttgctgc tgcaaacctt gcgatccaat atcgtacgct gttcaaaaag
     5041 gacttcttaa tcgatttaat cggttaccgc cgatatggtc ataacgaaat ggatgatcca
     5101 gcagttacgc aaccacaagt gtacaaaaaa attaaaaatc acccaactgt aagagcaatt
     5161 tatgcagatc aattacaatc tgctggcgtt ctgaatgcag atgaggttga aacaattact
     5221 cagtttatac aagaggaatt aaaggctgaa tacgcacaag tgccaccagc tgatacgagt
     5281 gctgcaacaa ttcacgttaa agttccagag gttgttgcaa aaggaattca accgattgac
     5341 actggtgttt caattgaatc acttcgtgca attaatgaag gactattatc ttggcctgaa
     5401 ggctttaacg tatatccaaa agtgaagaaa attcttgagc gccgtaaaga tgctcttgaa
     5461 gagaacggta aaattgaatg ggcacttgct gaatcgttag cattcgcttc aattttacaa
     5521 gaaggtacgc caattcgttt aactggtcaa gattcacagc gtggtacatt cgcgcaccgt
     5581 catatcgtat tacacgatac tgatacaaac gaaacatatt caccattaca ccgtttaccg
     5641 aacattaacg catcattctc tgttcataac agtccgttat cagaagctgc tgttgttggt
     5701 tacgaatatg gttacaacgt atttgctcca gaaactcttg tgatgtggga agctcaatac
     5761 ggtgacttct caaatactgc gcaagcatta tttgatcaat atgtttcagc aggaagagca
     5821 aaatggggtc aaaaatctgg tttagttctt ctattaccac acggttatga aggtcaaggg
     5881 ccagaacact ctagtgcacg tccagaacgt ttcttacaat tagctgcgga gaacaactgg
     5941 acagttgcaa acttaacgag cgcggcacaa tacttccata tcttgcgccg tcaagcatct
     6001 atcttaggaa cagaagctgt tcgaccatta gtaattatga cgccgaaaag cttattacgt
     6061 cacccactta cactttctac aggtagtgag ttaagtgaag gacgtttcca acctgcttta
     6121 gaacaaggaa accttggtgc gaaaccaaat aaagtaaaac gtcttgtttt aagtacaggt
     6181 aaaatggcaa ttgacttagc agcagaaatc gaaagtggta agcatgagta cagcctagat
     6241 gaagttcata tggttcgtat cgagcagttg tacccattcc ctgctgaaaa agttcaatct
     6301 attattaaac gctttaaaaa cttagaagaa atcatttggg ttcaagaaga acctcgtaat
     6361 atgggcgcat ggcattacat ggctccaatt ctgttcgaac tagctgggga taaagtgaag
     6421 acaggttaca ttggacgccc ggatcgctct agcccatctg gtggcgatcc attcgctcac
     6481 aaagctgagc aagaattaat cgttgcacac gctttagatg tgaagtacaa cttccgtcaa
     6541 gataaacaag aaattgaagt tttcagcaac tgaaagtaac aatgagtttt tcaggcttgg
     6601 ctgtggcaga tagtctgcca cagccaggct aacaaatgga gattaccgaa gattaaagaa
     6661 gataaaacac accgttaggc aaataagggg aggacattta aaatgatcga aattaaagta
     6721 cctgagcttg cagaatctat ttcagaagga actatttcac aatggcttat caacgtaggc
     6781 gacaaagtcg agaaaggtgg cagcgttgtt gagcttgaga ctgacaaagt caatgtagaa
     6841 atcattgcag aggattcagg tattgtatcg aagttactag gcgaacctgg agatacagtt
     6901 gaagttggtg ctactatcgc aattttagat gcaaacggcg cagcggttga agtaagcaca
     6961 cctgctccgg ctaatgagca accaaaacaa gaaactactg aagcaccgaa agcagcagct
     7021 ccaagtgctg aacaaaataa agcgttgcaa ggtttaccaa atacaaatcg tcctatcgca
     7081 tcaccagctg ctcgcaaaat ggctcgtgaa ttaggaatcg atttaaacga agtacgtagc
     7141 acagatccac ttggacgtgt gagaccacat gatgtacaag ctcacgctgc agcgccaaaa
     7201 gaagcaccag ctgctccaaa acaaagtccg gctccagttg caaaaactga atttgaaaaa
     7261 ccagttgagc gtgtgaaaat gtcccgccgc cgtcaaacaa ttgcaaaacg tcttgtagaa
     7321 gttcaacaaa catctgcaat gttaactaca tttaacgaag ttgatatgag tgcaatcatg
     7381 gaattacgta aagaacgcaa agatgctttc gagaaaaaac atgatgtacg tcttggcttt
     7441 atgtcattct tcacaaaagc agttgttgca gcattaaaac agttcccatt attaaatgct
     7501 gaaattcaag gcgatgagct tatcattaaa aaattctatg atatcggtat tgcagtagca
     7561 gctccagatg gattagttgt tccagttgta cgcgatgcta accaattgaa cttcgctgaa
     7621 attgaaagcg agattcgtaa tttaggtctg aaagcacgcg ataataaact ttcattaaaa
     7681 gagctacaag gtggtacatt tacaattaca aatggtggtg tgttcggttc tctaatgtcg
     7741 acaccaatcc taaatagtcc acaagtaggt attctaggga tgcataaaat ccaagtacgt
     7801 ccagttgcaa ttgatgcaga gcgtatggaa aaccgtccaa tgatgtacct tgcactatct
     7861 tacgatcacc gtattgttga tggtaaagaa gcagttagct tccttgttgc tgttaaagat
     7921 atgcttgaag atccaaaatc attattatta gaaggttgat agattattaa tctattaaag
     7981 gctgtagaat gaatcattct acagcctttt tttattgtgt tcatacggga caaatcacaa
     8041 tacatagact aataatgtat gcctaaaacg taagggggat aaacatgaat aaccttccag
     8101 ttcatgcaaa acttaaagca aataaggata ctttcttcct ccccgattca aacgggggtg
     8161 tttactttcg aaataactcc agttcattcc gtatggatgg tgatggaatt tatgactgga
     8221 ttgagaaatt aatgcctatg tttaacggta atcattcttt gacagaaata accgatggtc
     8281 tccctctccc ctatcaaaat cgtgtatttg aaattggaga gattttatat gaaaatggtt
     8341 tcattcgtga tgtaagccaa gatgctcccc acgaattaaa cagtgcatta ctcgacagat
     8401 acgcttcgca aattgagttt ttagaagctg attcccattc aggtgcttta aaattcgaaa
     8461 cgtaccgcgc agcaaatgtg cttataattg gttctggcga tatgcttact tccctagttt
     8521 cttctttatt agaatctggt ttacctacat tccattatct tgttacagat cgtgctgaaa
     8581 caaactacga tcgaattcac gaactaagcg aacgtgcata tgcaaatgat gacaatgtac
     8641 ttattcaaga aatagatatt acaattgatc gccctttaca tgaagtattc gagcctttcg
     8701 actggatttt atacgtttcc caaaatggag atattgaaag tttaagagca atccatacta
     8761 tttgtagaga gtttaagaaa aatttcatac cagctatttg cttatcaaga attggtttag
     8821 ctggacccgt cgtaaccgca gaccgtgaag aatgctggga atcagcttgg catcgtctac
     8881 acgaaactac tttacaaagt gaaaatccac ctgaactttt ctcaccaatt gcatctgcaa
     8941 tgttagcaaa tgttatcgtt tttgagttat ttaaacatgt cgctgaaggt tcacataggc
     9001 agcataatcc tcaattcttt ttattaaact tggaaacact tgaaggaaag tggcaccctt
     9061 tcataaaaca tcttctcgca accgatgaaa tctttacaat tgatacggtg caaaatcttc
     9121 aagaaaacct tgcccaacgt tccggacaat atacttcaac tgaacttttt cgtttttttg
     9181 atacgttaac ttctaaagaa gctggtatat tccacatgtg ggatgaacaa gatttacacc
     9241 aattgccttt atcacagtgc aatattcaag ttgcaaatcc attatcagac ggacctacct
     9301 ctccccttcc tactataact tgcggtggat taactcataa tgaagcacgc cgcgaagctg
     9361 gtttaacagg agttgaaaca tatgtagctg aaatgattca tcgtcttatc cccgaacata
     9421 ctgatatcgg tattggtgct ggggaaacga tgacagaagg tgtataccga gcactccaaa
     9481 aacatttaaa taataagtta tatgaacgcc aatcacatat gctagaagag attacagagc
     9541 tttatttaac cgaaattcat gataaacatt gtaggtttta ctacgatgct ctctctacaa
     9601 ttcatgaaat acctaaagta ggaatgagtg aggagttact tggttttcct gtcgtttgga
     9661 tcggtattaa tgatagatgg tatggtgcgg caaatattaa tataacactc gcattaagaa
     9721 atgctctgca acaagcactc cttcatattc aaaatgaaga gattccttat aaagctaata
     9781 tgttaccgga atcatccatt gttttatata gtacggatcc tgttagagta gcaatacaag
     9841 aagaggaaga aattccaggc gtacagtctt tacaagttgc tttgcaaaat ttaacggaaa
     9901 acaacttgta tccattcgtt tttgatttag ctattgagtc atttttaaga gacaacttag
     9961 acggtgtata tggggtatta attgcaaagg aggatgacca atgactcaaa acatactact
    10021 tataggagat ggcctactca cagactatgt acatgagcaa ttgtgtaagc aatattcact
    10081 catccgccag catacaatta cagaagctct ccctgaaaac attcatcttg ctctcgtttt
    10141 acatgacggg tctccttctt ccgtacatcg tgatgctgag cttatctttc gctcaaataa
    10201 tattccgtgg cttcgcgcgt ttacttcgtt tggtgaaggt attatcggtc cttacgtgaa
    10261 gcctcttaca actggatgtt cccactgcgc tgatggacgc cggtttatag ctggctttga
    10321 tcaaaaagaa atgtgggaac tacaacgaaa atatgcatta aaagcagaga acgtgacgag
    10381 gcgtgatgta cgcgccaccc aaaatggaat gttacaaatg tgccagctca ttcatgccga
    10441 aacagagaaa atattagctc atggatattc ttctttagaa aacgaactca ttttactgga
    10501 cttacaaacg ttaaaatgta cccggaattc gtttcttcca gaccctctct gtccggtatg
    10561 cagcaatttg cctgacgata cagcagatgc agcgcaaatt tctttacaac caagtttgaa
    10621 aacgagtact gaaacgtatc gctgtcgttc cattcatgag ctaaacacat ttttaacgag
    10681 agactattta gattaccgga ctggtatttt aaacggtaaa atgcaacatt ctctattacc
    10741 gtttgctgat gtcattataa acatgccgtt actgtttgga aatgaaggtg tcgcgggccg
    10801 gactcattca ttttcactta gtaaagcaac cgctatttta gaaggtttag aacgctattg
    10861 cggtatgtcg cctcgtggaa aaaaaacaaa tgtacatggc agttttcgtg agctagaaga
    10921 tattgcactg aatcccctca cacttggtgt gcatacaaat gaacattaca atcgtgatag
    10981 ttttccattt aagccgtttg atcctgatta tgagcaaaac tgggtatggg gatattcttt
    11041 attacaaagc aggccccttc tagttccaga atcaatcgct tattatagcc ttggtcatag
    11101 agatgctttc gtgtatgaaa catcaaatgg atgtgcaatt ggtggtagtt tagaagaagc
    11161 aatttttcac ggcattttag aaattgtaga gcgtgacgcc tttttgctca cttggtatgc
    11221 cgaattacct cttccccgtc tcgatcttag ttcagccaat gatactgaat tgcaactaat
    11281 gttggaacgc ttacgcacaa ttactggata tgaattatac gttttcaacg cgacgatgga
    11341 acatggtatt ccgagcatat gggtcattgc gaaaaataca aggcaagatg gtatgaatct
    11401 cgtctgtgct ggcggcgcac atatggaacc aattcgagct gtaaaaaatg caattcatga
    11461 aatagcgggc atgttactta taacagatga agagcttgaa caaaaaagag agaaatatga
    11521 aaacggttta caagatccat atcttgtttc gcaaatggaa gatcatagta tgctgtacgg
    11581 attgaaagaa gcggaagaac gtcttcactt ccttttacgt gatgatgctc cagtgcaaac
    11641 gttccaagaa atgaatgcat tacaatcatt tgatatggat ttaacatctg atcttcatca
    11701 acttttaaac aggttacatc aatctggact tgaagtaatt gttgtaaacc aaacggtccc
    11761 ccttatagaa aagaacggct tacattgtgt aaaagtaatt attccaggca tgttaccgat
    11821 gacgttcggt caccatctca ctcgggttac aggactggat agagtgtata ccgtaccgat
    11881 gacacttgga tattgggctg agcctttaac gaatgaaagt ttaaatccac atccgcatcc
    11941 gtttccataa ttcatagtga gggggaaatt tgatgcaacc tgatactttt ttacatcatc
    12001 tccatttttc tattaatgaa attatgtcgt ccgataaaga gattgactgg gaagacgcac
    12061 cacttcctta taaattatat cgaaatttac cagtaatccc tctctcttta gaaatcccat
    12121 taactttgcg gaattcttct actaaaccta acttagagga aatcggtcat tatctttggt
    12181 actcatttgg tttaacacaa ttatgtcagc ctactactaa cctagaaaat aataaaacaa
    12241 cgactctatt tcgaagattc atcccttctg ggggtgcttt atatccgaat gaattatata
    12301 tgtatttaaa aattgatcat tatccagacg gcatttacca ttacgacgcc gcgcaccacc
    12361 gtcttatctt acttcgtgaa ggaaattttg attcttatct tacagaagca cttggcaatc
    12421 gttgtaacat acattcttgc tttggtgctg catttgtatc cactatgttt tggaaaaact
    12481 tctttaaata caataacttt tcgtatcgtc tgcaaggatt agatagtggt gttctaatcg
    12541 gtcaattact tgaatgcgca aaacaatttg gttatacaaa tggtgtatat tttcagtttc
    12601 tagatcgggc aatgaatcat ttacttggac tgtcagaagg tgaagaaagt gtgtatgctg
    12661 ttattccttt aagtacagaa ccgaatacag attggtttca tgatgatcat cacgaaaata
    12721 aaactattac ttctcatgac ttgttgcagc aaatcctgcc gttaacacat gagcatttcg
    12781 ttcgctcaaa atatgtagat gaatatccga tgataaaaaa aataaacgca gcttctatga
    12841 ttgaatcaac agaacacttc caaacattta cccgtgaaga acgacaacaa tatagtgcac
    12901 acgctatgca gctacctaaa gtggaacgtt tatcatatga ttttttacaa ctttgtaaaa
    12961 aacgatattc acctgattct gacttcattt taacgaaatg ggatgcagcc gagctcgcta
    13021 ctctactaca agcagcgagc ctctccttcc cttattacaa cgaccttgat ggcaaatatt
    13081 taaatgaaaa cgcacgagtc tcactatatg gatgttttta taacgtaaaa gacatagaaa
    13141 acggcgctta cgcttataac agtaggacac attccataca gccaattcgg tacggagacc
    13201 ttcgttattc tctgcaatcc agtatgacga tggataacgt aaaccttttt caagtaccac
    13261 tttgtctaca tgtaatcgga aataaagatt actataaaaa taaattaggt tatagaggat
    13321 atcgaattca tcaaatggaa gctggcatgc tcgttcataa actcgtttta gctgcgaccg
    13381 ctatggggat gggcgggcat ccgttactaa gttttgatac aaattcatgc gatcaattgt
    13441 acgggattga tgccggaaat gaaacttcac tcattcaaat tccggttggg gcgtatcgag
    13501 cgcgaaattg gctaaaaggg tccttgcata attagaagca cgccgattaa tggcgtgctt
    13561 tttttaaagg agttaaatta ttaaaagcga aataaataca tattcttata taaaaggaga
    13621 gtttgaattg agtattttac aaaggttaat cgagcaagcg aaaaatcctc acgggacaat
    13681 tggttcctct atgctttgca ttatgaatgc tgcgcatacg agactaacaa attgggcttt
    13741 acaaaaaata catatacgtg aaaatgcagt tattttagat attggttgtg ggggtggtaa
    13801 aaccatacag actctttcaa accgaactcc gcttgggaaa atatacggga tcgactactc
    13861 caatcaagct gttgaaaact caaagaaagc aaatatgaag gatatcaaag cagcgaaagt
    13921 aattattcat caagcaagcg tctcctctat tccatatcat ccggacttct ttgatctcat
    13981 taccgctttt caaacccact acttttggcc tgatgttgag aatgatatga aagaagtatt
    14041 tcgcgtctta aaaccgaatg gatccttttt actagtcgct gaaactttca aaatccaata
    14101 tcatatggat acatttaaga cgaccgaaga attagtaaac cttttttatg agacgggatt
    14161 tacaagcgtg aaatgttacg aagaaagggg gtgcctttgt ttaataggaa ataagtaaaa
    14221 aagcagacca ttaggggtct gcttttttac tagattactt taaaaatact cttaatttgt
    14281 cttgcaaata accagttttt cgtaccgtag ttatcattta gactatctaa attaatagct
    14341 ttcccgttag aaaactttag ttctaacgtt gtatttttgt catttgtttt taagttgcta
    14401 tttgtaatgt catcatactt taatttttca atctcaatat actcttcctt ctcttctccg
    14461 ataacgacgt gatcttggaa gaagaagaat acttctactt tcttaccgaa acaaaatacg
    14521 tttttcgtat aaattaatgt cgcgttatca agtccgacac atacttcttt catctcttca
    14581 acaacgtttc ctaagtcttc ttcgtttctt gcatttgatt cagcaatcca ttcttcgatt
    14641 gtattcatgt taattgccat actgtgcccc ctggttcgtt cattgctttg ttaaaaaata
    14701 aatactatat gacaatataa gcgatacgta ctatgttttc aagggtgaac ggtatattca
    14761 aaataaagtg aaactttatt tattcccctt tcacaaaaaa aatagcactt aaaaaagtgc
    14821 tattccgctc tccttgctgc ttgttgaatt ggatcccaaa cgctgttata tggtggtgcg
    14881 taacttaagt cgacatcttc taaatcgtga atactcattt tattgaaaag tgccatcgcg
    14941 ataacatcaa tacgtttatc tacgccctct tctccaatta cttgaccgcc taataattgt
    15001 ttcgtatcgg cgtgatatag taatttcaag tgaagtggcg aagcactcgg ataatagccc
    15061 gccatatttg ttgaatctac tttgaccgtc ttatacggga tgtttagccc tttcgcttct
    15121 ttttcattta agcctgttct tgcgagcgtc agattcataa atttaataat gcctgtacct
    15181 aacgtacctt tgaatgctct gcgtttatca accatgttga gtccggcaag tcgcccttgt
    15241 ttattcgcag tcgttccgag cgggatatgg tcatgaattt cctttataac atggtaatgt
    15301 gttgcacaat caccagcagc atatacgtct ttcacattcg tttgcatata agcatttact
    15361 tcaattgcac ctttatggtt tttacgtata tttgtcccct caagaaaatc agtatttgac
    15421 tgtacaccga cagatactaa aacgagatca gttttatacg tccctttatc cgtctccagt
    15481 tgttctactc tttcttttcc tttaaacgct tttacatttt cattcgttaa aatttcaata
    15541 ttatgtttat ctgcttcttt atgtatatat tccgccatat cggcatcata aattgtgcca
    15601 atatgatcgt ttcgctcaat cattcttact ttcttaccaa gttcgacgaa tgtttctgcc
    15661 atctctagtc caattgcacc gccgccaata atcgttacgt gctcaacgct atttgtttgt
    15721 agcgcgccta ctatacgctc agcatccgga attgttttta aaagatgaac accttctaaa
    15781 tctttacctt cccaatccgg cataacaggg cgtacaccag tcgcaattaa taaacggtca
    15841 tatgaaaatt caaatacatc tttcgtcttc atatgtactg catatacaat tttcttttct
    15901 gtatctactt tcgttacttc atgacgcact ttcgcatcaa ttccatattt atcacgaaac
    15961 gtttttacat cgcgtgcaat taacttttca gtagaggcga taacaccact aatcacatac
    16021 ggtaatccgc actgagcgta tgaatagatt tcaccttttt ctaacgttac aacatttgca
    16081 gtttcatcgt ttctaacaat ttgcattgct gcactcatac cagctgcatc tccgccaata
    16141 atgacatagt tcactttacc actccttctt tttacatact ctttacgatt tccatatttt
    16201 atagaaataa cacctacttc tattgtaaag aatgtgcatt tcatctacaa atttggtgca
    16261 caaacctatg cttgaatagg tatccgtcgt gtcttataaa caacatgtgt aatatgctat
    16321 aacagaagca attgaaagta ggtgaaatat acatgtgccc tggccttctc gcccaaactc
    16381 cagaggaacc gcaagaaccg aaagccgcca cgccacttga ccaagaattt tccattaacg
    16441 caacaatata cagcgctcgt gcttggttgt ctgacaatga tacttacgct caagatattt
    16501 ggaaaggcac tcgcttcgct tcagcatcac atgctggtaa gtccatattt ccaagtggta
    16561 ctattaaagt tattaactta tcttcagata caataacagt tactacatca ggagaggcag
    16621 atcatactct caaaacagtc gtaccacccc attctgaagt ggctttatca cccagttcgt
    16681 tatccgctgt acaggctagt acatccggaa aggcaagtaa agtcacattc ctctttcaca
    16741 tctttttctc aagggatccc ggtccagcta aacaaccata gaaaaggtac agtaatatac
    16801 actgtacctt ttctatgcac tctattctct tgatttaatc agttcaacat tataagattc
    16861 cacactcgtt aacgttcccg taaaatacgg attttctcta taccaagact gttttgaaaa
    16921 atacgcttgc atatctttcg tttgaaacat atgtccatgc cttgcgtata tttcatttct
    16981 agcaattttc aactgttctt tcgataaata tgttaattcc gcactcgtta attttcgaat
    17041 atcactatca gggaagatga aaccattata tacatacccc gtcgcaggcg gcggagtaac
    17101 attgtaaaca actgtttttt ctacactttt cttttgaaac ggaagattat aagccgaaag
    17161 tgctgttacc gtttctactt tcgtcgtttc ccttccactt tctccatttc gttctaaata
    17221 aatcgccgca cttccatcag tcgctatcgg tccccacgta atttcttctc cggtcaacac
    17281 tgtaactggc ttttgattca cgtataatgt cgcaccaggc gcattcgttt gaactgtaat
    17341 atattgccct tgcagtgtta aatctatcgt tacattattt tgactttgtt tcataagtac
    17401 aaccttttcc tcacgtaata gttttacata gtcattttta tattctgctt gaaatacttg
    17461 agttcctgga agaaacggtc catattgctt gtcaaacttt ttatcatttg ttttatcaat
    17521 ttcttttccg ttcaatttta aagatgtacc tttttcattt gtaagcagag tcgtataata
    17581 cgtcttcgct ttcaatttat accgatcaaa taaaacgaaa tacttcccgt ctttcgttaa
    17641 agaaaaatct gctctttcta ttccatcccc ttgtttttca ccttgcctca aatattcttt
    17701 caattcattc acgtaagatg gattttcttt tatatatgaa aatagaggcg ttacactctc
    17761 tctcgttaca ataacggctg gatcatctgt cgtgacaatc tcagctaact tctctccgtc
    17821 cctctcttgt aaaacagtaa taattctctc tacttgcgat gattgtgagt aatatgaaga
    17881 tccatacgca tataatccgc ccaatactat aataaaaaat gttaaaagtg taattccaat
    17941 tattgtccct ttgctcattt tttgcttctt tactagagga ttccccctct tcgtcccgca
    18001 gttttgacaa aattgcacac cgtcttcaaa atgaatccca cactttgtgc atacattcat
    18061 ccgttcaacc accttttcgt tagaagccag ttaatccctg tgtaaaggtt tgaattatcg
    18121 tgttaatgta agaccaaaac acaataaacg ttgcaattcc aattaaaaca tttgcgataa
    18181 gaagtgtgta cacaggatct aatccaccgt tatctagttt taatatagct acaattatac
    18241 taattaccat atacgttgta gctatccata gtaatattgg taagaaaaag attaataaga
    18301 aactaaaaag aaaagaaaga actagtatag caatagctgg cgtcgctatc gtcccccata
    18361 taccgaatgc ttcaagaaaa gaaaaagatg atttcatcat cttaccactt acaaaaataa
    18421 taaatccgac aaataaagtt aaaattaata aaaagaaaaa gaccattaca gattctccaa
    18481 agaaagtagg agtagctata tctggcacta atgtcctcgt aacagtcgcc gctgcgctca
    18541 tcattctata aaaaatacat gctcctaaaa aacaaataag tacaaggctt gcaattccat
    18601 ttcgcacttc aatatttcca ctttccataa tggccgatgg tgatttaaaa gcatttttaa
    18661 agaactgaaa atagccactt gcaaattgtt tcgcttgctc taccgtttca ttcggacgag
    18721 tttcctttac tcgtgccggg cgcgatagct gcccttcttc ctgcccacca ctcgctacca
    18781 cttcttccgt taacgaatgt ccacaattcc cgcaaaacct tgcttccgct gcattttcag
    18841 tattacatgc cggacatttc attctctcat ccctccttaa gcatatacct tatagggtgt
    18901 tacaaattca atatatgact ttgtacataa aacatgacta caagaaaaag aatatgaaat
    18961 ccttctttta aacgaaacta tgtgtgctag tattatagaa aaataatggt attatgaaac
    19021 aaagcaaata aagtgaaact ttaaacagat tggatgaaga cagtggaatt tgtaaactcg
    19081 atttttcaaa cactccttac aagcgtgatc caattatttt ctttaattgg tgtcatcatt
    19141 gtaattggat ttatattagg ttatttagaa tctctcacac gaacgtattg gtcgagagct
    19201 tttggtagga aaggttttct tttaaccgcg tggattggtg ttcccgttca tgagcttgga
    19261 catgcaatta tgtgtctagt atttcgtcat aaaattgtag caacgcagtt tttcccaaca
    19321 gatacaagtc agggagcttt aggttacgta caacatcaat acaatcaaaa aagcatatat
    19381 caacgaatcg gtaatttctt tatcggcatc ggccctatta tttctggtat tactgcctta
    19441 atacttttaa tgcgctattt cgtaccagag tcatattctt tatttaatac gactcttgaa
    19501 acaacaattg cagcgacttc tattaactta gaaatgatcc aaaacatgtt tttatcaaca
    19561 ttctttttat taaaaagctt gtttacaatg agcaatttat tgaccccttc tttttggtta
    19621 tttttattta tcgctatttg tatttccgca catatcgctt taagtaaacc agatattaaa
    19681 ggatccatag acggtgttat cgtcatgttt atcatgttat ttttattcaa tttaattgca
    19741 ggactttttc agtacgacag taaccaactc atcggcaaaa tgatgaaata taatatgtat
    19801 ctcattgcat tttctagtgt ggcgctgctt ttctcttgta tttctacact tgtgagtttt
    19861 gggttttata aaatgagagg aggacgttcg ttgtgaacgt cctcttctct ccttaaataa
    19921 ttatttatca gctttaataa gttattgaat cggaataggt ggtccaattt ttttgttttc
    19981 tttccccgaa tacggtacaa gtgaatattt tcccaccgct acatttattc catcaaatct
    20041 actaaaagaa ataccgccat cttcattcga tataaccacc tctttaaatg tatgtgcttc
    20101 cccagattct gattcgattt taaaataaat atcttcattt gtactttgtg tcacatcata
    20161 ataaatcgtt gtggaaatcg gcgtagaaac tactttgtta acagttactt tattgccatc
    20221 gtataaagca attgtttcat ttaaatcaaa cgtccgcttc tctttcatca actgagcttg
    20281 tgatacttca atagcaaata tccatggttg ctcaattaca gtatccctgt tgaatgtatc
    20341 ataagtaatt tcgatttgaa gtgcatcagt ttgtggtatt tcacttaact cgataccacc
    20401 gtaaattgta aacatagaat catttactgc aattgattgt gcatcctttg tattagaaaa
    20461 gtcacgccca tttattcgta cctgtggaat taaatatgtt tgataatcaa atttcacacc
    20521 cttcgctggc tcaaatgttg aactgatgaa taatttattg tcatccacta atacctcatt
    20581 taacgtcagt ttaccgtatt tattttcagc agttttccca atagccgttt tatagggaga
    20641 atagtcaagt ggttgctgtt tatcaatata tttttcaatc aatcccgcaa taaatggcat
    20701 atttgctaaa gatgtttgtc caagtggcac tgtaatactg acaattaaca tgcaagctgc
    20761 tgcgactccg aaccattttt ttgttttttt atttttgcgt agcttatttt tcacacgttt
    20821 ttcccactgc ttttcctcta ttttggttaa gggagtctcc tcaaactctg tgatgtccaa
    20881 ctgaatatca tttaactctt tataaataga catgccctca cactccattt ttaaaaataa
    20941 aaatctgttt gagctttttt cgtccgcgtg acagtttgtt atgaatccat gactctttca
    21001 cattaaggtg ggatgcaatt tcacgagacg gtacaccttc taaataatac ttttcaaaaa
    21061 tgttacgctc tgttgctgac aactcactaa gcaattcctg tacgtctaag aagtcatttt
    21121 gttttctttg ttcttgatac agacgatcat taatctctgt acagacacag acagtttgtt
    21181 gctgatttct cgcatttttc cgctgataat caattgcccg atatttagca atggctgcta
    21241 tccattgttt aaacgtattt ttacttgaat caaatgaatc gatatgaaac caaatggcta
    21301 ataatacatc atctaagcat tcttcataat cttgctgatt actctgtaca tatcttttaa
    21361 taatcacgct tagtaaaccg ccgtatgttt gaataataaa cgtaacgctt ttctcattac
    21421 gctttttaat ttgttgcaca acattttctt ccgttatctt caaaggtaga cctccttgtc
    21481 ctgctaattg ggtacctact ttctaatacg aataaaactc aataacccta tcaccatttt
    21541 taatattaca aacataattt catcactata tatcttgtat acaatgagga gagggcgttc
    21601 attgtgaacg ccctcttctc atcaattatt tctcttataa tcacaatgct caaccggaac
    21661 acgagcgtgc ccttcttcat cggtacacca tgactgtgac tgaaaggcaa gaaaaatacc
    21721 aatccactct tccttcttct caaagtgaat caatatccca ccgtcttgcc atttgccatc
    21781 atcaccttgc catttctcta cattcccttg attcatatga atatcgtgta taccgtttcc
    21841 aggtgtaaaa tggaaatacg aatccggaac cttttcttct ggtccccacc tttcaccaaa
    21901 cgcataaata attgctttct catctattgc tcgttttata taacgttcta tcttttcatt
    21961 taaatcatta tcagatcccg ttttttcagc tggcaaagga atcatttgct ttgaatcaaa
    22021 taaattacct cttacataat ctaaagctac tttcggctca ttgtttttca cttctgtaaa
    22081 cccaaacggt aatgttggta aaatgtgaat agcttctgaa tcaatatgtt cgcttgcaaa
    22141 atataaaact tctgacggat aactttgcga ctttacgtta attgcaatac gataatctac
    22201 ttctgcttcg ccttgtaaat gaacttgata atgaggtgtt ttcccttttc caatcttaga
    22261 ttgtacaact gtacctttta atacaccgta gttttttaag ggcatctctt tcatctccta
    22321 ttcatttagt agaagctgtt catactttag gcattatcca tataaaaaga aaatcctcct
    22381 ttcccaggag gatttcttat tttctcaaca tataccaaac aataacctcc accactacaa
    22441 gcaacaccgc accaaaaatc attaacgtcg tcttctttaa tagttcattt tcacgataag
    22501 ggatattaca taaatacgcg cctagtgtaa tccgtgatgg acaagcgatt gtggctactg
    22561 atgatgcggt gttttggagc gttgtgacgt attgccacgg gagtgctacg ttttgcgctg
    22621 tttgcatttg tagctttata aacatcgcat ttgatcctgc gttactacct gttaaaaagc
    22681 ctccgattcc cccaataaat ggagcaacga aaacgaaaaa cgtaccaaat gtttcaccag
    22741 ctgtttttgc gagtaatgaa tgcataccag atgcgcccat tagttctgaa atggcgatga
    22801 acatcgtcgt tgtaattgcg aatggaatcc attgtcttat cgtttgcgag agtgattgtt
    22861 tcataatatt agatggaatg cggaagaaaa taattgtaaa taaacaagtc atggcgagcc
    22921 aaaaccctgg cgaatatagt aactctagtt tgtaagagta tgattttaaa tcgagaactg
    22981 catatgacct aagaaaatca tgtaatgctg gaacgaggcg agaaagtaaa atacaaactg
    23041 ttaagaatat ataagggcta ataattttta taatagatac ttctctctct acagccgcag
    23101 catgttctgt tataaagttt tgctcacttt tcccttttaa tttaatgatt agaaagccaa
    23161 atgtaatggt aacgatagaa cttaatatcc ctgctagttc cacacttacg tatgcgttag
    23221 aaagatagat tccgagagaa aataatagaa agaatcctat cccttccttc cacttttcta
    23281 taactgcctg cctgccaccg acaacgtata aagaaaggaa gataaaatat gcgaaaatcg
    23341 ggatgcttaa taatgctgta tttgtaccca gagttgtgag tggcatgttg ataagctgag
    23401 aaccgataat cgtacccgtt gccatcgcgc cccatgaact tgcaagtaaa ccgataaacg
    23461 atagtagcac agcttgaaac ggtttataac cgagcgaaag aaaaataggt gctgcgacca
    23521 taaaaccaat tccga
//
