LOCUS       NZ_JH792251            23909 bp    DNA     linear   CON 15-MAR-2024
DEFINITION  Bacillus mycoides strain VD078 supercont1.1, whole genome shotgun
            sequence.
ACCESSION   NZ_JH792251
VERSION     NZ_JH792251.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5172041)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A., Chapman,S.B., Goldberg,J.,
            Griggs,A., Gujja,S., Hansen,M., Howarth,C., Imamovic,A., Larimer,J.,
            McCowen,C., Montmayeur,A., Murphy,C., Neiman,D., Pearson,M.,
            Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P., Sykes,S.,
            Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Bacillus cereus VD078
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5172041)
  AUTHORS   Feldgarden,M., Van der Auwera,G.A., Mahillon,J., Duprez,V.,
            Timmery,S., Mattelet,C., Dierick,K., Sun,M., Yu,Z., Zhu,L., Hu,X.,
            Shank,E.B., Swiecicka,I., Hansen,B.M., Andrup,L., Young,S.K.,
            Zeng,Q., Gargeya,S., Fitzgerald,M., Haas,B., Abouelleil,A.,
            Alvarado,L., Arachchi,H.M., Berlin,A., Chapman,S.B., Goldberg,J.,
            Griggs,A., Gujja,S., Hansen,M., Howarth,C., Imamovic,A., Larimer,J.,
            McCowen,C., Montmayeur,A., Murphy,C., Neiman,D., Pearson,M.,
            Priest,M., Roberts,A., Saif,S., Shea,T., Sisk,P., Sykes,S.,
            Wortman,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, The Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (05-APR-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Taxonomic-Update-Statistics-START##
            This Genome (query)               :: GCA_000290895.1
            Current Name                      :: Bacillus mycoides
            Previous Name                     :: Bacillus cereus VD078
            Date Updated                      :: 2018-06-08
            Analysis Type :: Average Nucleotide Identity (ANI)
            Analysis 1 (A1) :: Query vs. TYPE genome for current name
            A1 Genome (subject)               :: GCA_000003925.1
            A1 Name                           :: Bacillus mycoides
            A1 ANI                            :: 98.66715%
            A1 Query Coverage                 :: 80.95%
            A1 Subject Coverage               :: 88.35%
            Analysis 2 (A2) :: Query vs. TYPE genome for previous name
            A2 Genome (subject)               :: GCA_002014665.1
            A2 Name                           :: Bacillus cereus VD078
            A2 ANI                            :: 89.90313%
            A2 Query Coverage                 :: 68.38%
            A2 Subject Coverage               :: 77.02%
            ##Taxonomic-Update-Statistics-END##
            ##Genome-Assembly-Data-START##
            Assembly Method                   :: allpaths v. R38749
            Assembly Name                     :: Baci_cere_VD078_V1
            Genome Coverage                   :: 146.0x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000290895.1-RS_2024_03_15
            Annotation Date                   :: 03/15/2024 02:24:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,225
            CDSs (total)                      :: 6,127
            Genes (coding)                    :: 5,875
            CDSs (with protein)               :: 5,875
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 3, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 252
            CDSs (without protein)            :: 252
            Pseudo Genes (ambiguous residues) :: 0 of 252
            Pseudo Genes (frameshifted)       :: 92 of 252
            Pseudo Genes (incomplete)         :: 158 of 252
            Pseudo Genes (internal stop)      :: 71 of 252
            Pseudo Genes (multiple problems)  :: 58 of 252
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:24:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1767244
            Orig. end                         :: 1791153
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JH792251.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The organism was changed from 'Bacillus cereus VD078' to 'Bacillus
            mycoides' in June 2018.
FEATURES             Location/Qualifiers
     region          1..23909
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23909
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23909
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13909](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13909
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            306..1427
                     /locus_tag="III_RS09120"
                     /old_locus_tag="III_01811"
     CDS             306..1427
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001989492.1"
                     /locus_tag="III_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01811"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_234710388.1"
                     /transl_table=11
                     /translation="MKKVFVDIYLMFNFGDDLFLDILVKKYPNCYFTVNHLGSNYDQFI
                     SQYNNVSRRKYTLLNKIGQRLKLSDNITNYEKIAEEHDALLFIGGSIFREEAYHSSLYR
                     DRMKMVMEFKRRKKLVFIIGANFGPFKTEEFLDDYRKFFELCDDVCFRDVYSYQLFEDL
                     PQVRCASDIVFQMNTDEYRLDLSEERIGFSIIDVRHKQGLTHYYNDYIRSTIKTIELLV
                     NKGNKCYLMSFCEQEGDLDVINTIQSRLSSNALDNIVIYKYRGNLKEAIETMASFKLLI
                     AARFHANILALLLGIGIIPIIYSQKTINLLKDIDFNKTLIDMENLQLQYDEKVIDASID
                     YKFNLESTIIKAKKQFEKLNDFLGSEAVKSEGI"
     gene            1424..2611
                     /locus_tag="III_RS09125"
                     /old_locus_tag="III_01812"
     CDS             1424..2611
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001989489.1"
                     /locus_tag="III_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01812"
                     /product="glycosyltransferase"
                     /protein_id="WP_002167798.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.6e-32,
                     bitscore: 108.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNIIFMIINMNVGGTEKALLNMLSEIPKDKYSITILMLEKYGG
                     FLNSIPREVHIKYFEEYEEIKDILNEPPHIIFLNLLREGKIIRGSRIMLLHLLTKFIKD
                     RSLFFKYVLREYPIVEGEYDIAVAYAGPMDFISYFVINNIKAKKKFQWIHFDVTKITFN
                     QIFSDKLYKKFDHIFVVSNEAKYKLLSIIPSIKKKTEVCPNIVSAKLIQNEAKEGKRFN
                     DNFLGIRILTVGRLTNEKGQDLAIKVLARLINEGYKVRWYCVGEGGARKEYEKLITEYG
                     LERDFILLGELSNPYGYMATCDIYVQPSRYEGFCITLAEAKCLHKAIVTTNFTGAKEQI
                     KNRETGMIVNISESDIYEGVKSLIDNRSLCEVFSGNLANENFDKTLELKRNYEFF"
     gene            2680..4236
                     /locus_tag="III_RS09130"
                     /old_locus_tag="III_01813"
     CDS             2680..4236
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842012.1"
                     /locus_tag="III_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01813"
                     /product="oligosaccharide flippase family protein"
                     /protein_id="WP_002167799.1"
                     /sec_met_domain="Polysacc_synt (E-value: 3.4e-18, bitscore:
                     64.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSQIKAGAILSYAALVINSSISLLYTPIMLKLLGQSEYGLYSLA
                     TSVAGYVGVLNFGLGNAVIRYTAKYRALKDEENCSRLYGMFSIMYGVLGGIALITGIIL
                     TLTADSIFSSSLNVDEINKLKTLMVIMVINISIGIGFGFFSVVVLAYERFIFQKILGII
                     GAIVVPLIMLPLLIKGYGSVSIAIVTTSINFIIIAINMYYCFKVLRIKIVFKKIEIGLL
                     KEILGFSSLIFLNLIIDKIYWSTDQVILGIYSGAAAISIYTIGASFTGYFSGLAAAISN
                     VFLSRITGMVTKKASDKEISDLFIKIGRIQYIILSFVLSGFIVFGQEFIHLWVGKEYNE
                     AFIIAIIILVPMIVSLVQSIGGIILQAKNMQGFKSITYVVTSFVNVVISIIFVQWWGAI
                     GSALGTAVAFTIGNIIIMNIYYWKKINIDIPRFWTNITCMSLAFGASLVFGMTLNRWIL
                     ADKWQELFVKIILFSIVYICLMWVTGMNKYEKDTFRQVIQNILYRFKRKKVIQDTSSNT
                     D"
     gene            4695..7187
                     /locus_tag="III_RS09140"
                     /old_locus_tag="III_01815"
     CDS             4695..7187
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001989486.1"
                     /locus_tag="III_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01815"
                     /product="hypothetical protein"
                     /protein_id="WP_002167801.1"
                     /transl_table=11
                     /translation="MTIYTVELERWGINNDGTAAVKTTQGLNDALLWANKEGFQIVVLP
                     KGKYLIEKTSSVKLCSNTTYRFYECVFEKETNNLIKYNILLCDGIKNVEIIGAIVKGDR
                     ENHDYSSGGTHEWGHGIECKNSCYNIYVKNCEVSECTGDGLVTSMDFSAIGGMSHPDHF
                     AKGDIDSKGNLDITKVNYTTVVKFFDITGDIVKSVGYFYYSGDGYGGYGSGCNLNKVTI
                     KVHFYAGNGSYLGYRNFRSYEFVYLDSLPTGTTKVRFSFLQNYDLMNSNLHYVMCANIP
                     QYVYFFGCKSYKNRRLGASINGGRFITFDGCEVFNNSNAMNRSIGCNPGYGIDIEDGYM
                     NNQKITIRNSDIYDNRAGAFVCISTRGLYLESNKMKGNVYLSGSGDDYFSINNMYYGAI
                     TGRSITSGIEADGTFCTFRNDTIFGQNCGIVGGNTTLENCVFSKSTIALSGETVKIINC
                     KFTFDDPDKDGIIDFRSKYLEIRNSLFDIRRAKSIATTGYGQTETAIFSSVKFLTNECN
                     GGHYIGAKNLIVEDCEFIHSGRTANYSRMMAAESMRVEKTTFKNQSFRFDGGDIYGIES
                     LAKDKGYITHVFSRNQIIWDAPYGLAVHEARGAGVAFIYIPRIEITDNKFEVNGKDVSL
                     GSLHTIRIFVENYLKLCDNTIITKNDSGINTTGNITIEGVYRKQNSTLPVPRTAILVQD
                     NKKINSNITFTNNVNNQLEKNILGNLPQSSLVSLEPTFGTFSRGELLYNDTPTVGGYIG
                     WVCITAGTANKNFWIAEKEYQINSFINANGKVYKSVVAGTSGKIAPSHTNGTSKDGNIL
                     WEYVDVLAVFKRFGLISD"
     gene            7296..7910
                     /locus_tag="III_RS09145"
                     /old_locus_tag="III_01816"
     CDS             7296..7910
                     /EC_number="2.7.8.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199623.1"
                     /locus_tag="III_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01816"
                     /product="sugar transferase"
                     /protein_id="WP_002167802.1"
                     /sec_met_domain="Bac_transf (E-value: 6.1e-66, bitscore:
                     219.6, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLFDVCVSLLLLLLFSIVICIVAILVRIKLGSPILFKQKRPGM
                     NGIPFYLYKFRTMTNEIGGDGNWIPDEVRLTNFGKTLRKYSIDELPQLINVIKGDLSLV
                     GPRPLLMEYLPLYSSKQAKRHDVKPGITGWAQINGRNSITWEEKFELDIWYVENHSFLL
                     DMKIIVLTITKVFKPEGINHVGHVTMERFTGGDVEIKGDGK"
     gene            7907..8539
                     /locus_tag="III_RS09150"
                     /old_locus_tag="III_01817"
     CDS             7907..8539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002167803.1"
                     /locus_tag="III_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01817"
                     /product="acetyltransferase"
                     /protein_id="WP_002167803.1"
                     /transl_table=11
                     /translation="MKILIIGCGGHSKVVKDIILSNEGYEIVGYLDDLYTGITIIDNLY
                     FGAIEDAREIINNFNDVKLVIAIGNNKMRKEISGILNQPVGIYATLIHKTAIISPHAHI
                     GNGTVIMPNVVVNADTIIGNHTIINTGSIIEHDNIIDDFVHISPHATLTGSITIEEGAH
                     IGASATIIPGVKIGSWSIVGAGSVVINDFPSNCTAVGIPAKVINVVN"
     gene            8556..9713
                     /locus_tag="III_RS09155"
                     /old_locus_tag="III_01818"
     CDS             8556..9713
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (40-166). E-value:
                     1.1e-08. Score: 26.5. Matches aSDomain:
                     nrpspksdomains_III_RS09155_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000972897.1"
                     /locus_tag="III_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01818"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_002167804.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-96,
                     bitscore: 322.5, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.8e-07, bitscore:
                     26.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKNKEKIYLSSPHMSGNEQKYIQNAFDTNWIAPLGPNIDGFERE
                     LASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSFTFVASANPIVYLGAEPVFI
                     DSEPETWNMSPNALAHALYEANKVGKLPKAIILVHLYGQSAKLDEILSLCNQYNVPIVE
                     DAAESLGSTYKGKASGTFGRFGVYSFNGNKIITTSGGGMLVSNDVEALERARFLATQAK
                     DPAPHYEHSEIGYNYRMSNILAGVGRGQLEVLEDRVRTRRCIYKRYYEALSHMPGFYFM
                     PELENTRSNRWLTTLTIDEKESGISIGKLLRTLAEENIEARPMWKPLHMQSLFKEKKYY
                     PHSKNEDVSQYLFQSGICLPSGSNMLAEDQQRVIQGILKAVEWKN"
     aSDomain        8676..9053
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_III_RS09155_Aminotran_1_2.1"
                     /evalue="1.10E-08"
                     /label="III_RS09155_Aminotran_1_2.1"
                     /locus_tag="III_RS09155"
                     /protein_end="166"
                     /protein_start="40"
                     /score="26.5"
                     /tool="antismash"
                     /translation="GFERELASFVGVKGGAAVSSGTAAIHLALRLLDVQKGDTVFCSSF
                     TFVASANPIVYLGAEPVFIDSEPETWNMSPNALAHALYEANKVGKLPKAIILVHLYGQS
                     AKLDEILSLCNQYNVPIVEDAA"
     gene            10001..11938
                     /locus_tag="III_RS09160"
                     /old_locus_tag="III_01819"
     CDS             10001..11938
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274520.1"
                     /locus_tag="III_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01819"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_002167805.1"
                     /sec_met_domain="GATase_7 (E-value: 5.4e-20, bitscore:
                     69.8, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.5e-22, bitscore:
                     79.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIIHFTNEPVSIEHGREVMSRLYKYPADDIQIWHKENAFL
                     GCHAQWITPESVGEQLPFYNYEKQLAITADAIIDNRDELFEKLQVDYSDRKNMTDSELI
                     LLSYQKWGEAAPKYLVGDFAFMIWDEKKQTLFGARDFSGSRTLYFYRGEEKFTFCTIIN
                     PLFSLPYVEKKLNKQWIAEFLAIPVNFESVDPQLTVYKYIEQVPPSHTILVKEGEVKFS
                     RYYTPTVGEMLNLKSNEEYEEAFREVYQSAVKARLRTHHQVGAHLSGGLDSGSVVSFAA
                     SDLRAENKKLHTYSYVPVEGFEDWTHKGRIADERPFIQSTVEHVGNIQDYYLELPERSP
                     LSEIDDWLETMEMPYKFFENTFWLSGVYEKASQNGIGVLLSGQRGNWTVSWGPILDYQA
                     MLLKKLHWIRFYRELHLYSRNIGVKKSRVFEVVRRKAFPFLHQLLFSGKQDANSAIINP
                     EFAREMNVFDRLREQDIDITGTSISNAYDMKREQFEKPYYWSINGTYETKLSLRYALWD
                     RDPTNDLRLIQFCLSVPEEQYVQNGLDRALIRRATKNFLPDKVRLNQRVRGIQGADGVY
                     RMAPFWNEFIEEVEELSVDPVISEFLNVEVIKKAISKICKEPRPEYAFDLDFRILMRSL
                     IFYRFIKKAM"
     gene            11954..12079
                     /locus_tag="III_RS32860"
                     /old_locus_tag="III_01820"
     CDS             11954..12079
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172970.1"
                     /locus_tag="III_RS32860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01820"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_000712621.1"
                     /transl_table=11
                     /translation="MKKEWKQPVLEVLNINMTMAGPGHKYPDAVQPDPDDPVKYS"
     CDS_motif       11954..12013
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKEWKQPVLEVLNINMTMA"
                     /locus_tag="III_RS32860_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12014..12079
                     /prepeptide="core"
                     /locus_tag="III_RS32860_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-15.80"
                     /molecular_weight="2264.4"
                     /monoisotopic_mass="2263.0"
                     /core_sequence="GPGHKYPDAVQPDPDDPVKYS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEWKQPVLEVLNINMTMA"
                     /leader_location="[11953:12013](+)"
     gene            12157..13128
                     /locus_tag="III_RS09170"
                     /old_locus_tag="III_01821"
     CDS             12157..13128
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016108921.1"
                     /locus_tag="III_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01821"
                     /product="aldolase"
                     /protein_id="WP_002128587.1"
                     /transl_table=11
                     /translation="MFDSMGNVLYQAFGLKIVSEIPLPELSQLNEKKEMADVQVEITDL
                     SEQWGEYSAEKQKTIVVEDDIVMFHVPQTAIFAIQSGEKITFSPMANAEEDKIRLYILG
                     TCMGALLMQRKILPLHGSVIAIDGKAYALIGDSGAGKSTLASAFLNKGYKLLSDDVVAV
                     SLLNKNTAIVHPSYAQQKLWQESINELGMEVAQFSPLFERETKYAVPVNSQFFPDPLPL
                     AGVIELVKTQGEDIEMTRIEGLARLYKLYRHTFRNSLISKLGLMEWHFETSSNIASGME
                     IFQVSRPASRFTAHELVEVILNTIQKGSMVDGCPLEKNIIRT"
     gene            13091..13399
                     /locus_tag="III_RS09175"
                     /old_locus_tag="III_01822"
     CDS             13091..13399
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002128586.1"
                     /locus_tag="III_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01822"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_002128586.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.7e-26,
                     bitscore: 88.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.1e-15, bitscore: 54.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVHSRKISLEHNVVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEI
                     GGEIWELIEKPIIINQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQIKDQPNR"
     aSDomain        13130..13378
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_III_RS09175_Stand_Alone_Lasso_RRE.1"
                     /evalue="3.00E-28"
                     /identifier="RREFam002.1"
                     /label="III_RS09175"
                     /locus_tag="III_RS09175"
                     /protein_end="96"
                     /protein_start="13"
                     /score="88.7"
                     /tool="antismash"
                     /translation="VVQSKGNIVSDMDGEKVMLNVQKGNYYNLGEIGGEIWELIEKPII
                     INQLVTMLVSNYDIERKDCEEQVLSFLECLFQEGLIQI"
     gene            13436..13909
                     /locus_tag="III_RS09180"
                     /old_locus_tag="III_01823"
     CDS             13436..13909
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012261438.1"
                     /locus_tag="III_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01823"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_033713202.1"
                     /sec_met_domain="PF13471 (E-value: 4.5e-23, bitscore: 79.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVKRLRMFLSLNMKTKLLFLEAFIFLGWARVLKNITFSKVAPS
                     LGDYMSETSSTHIQPHGDTLKKVSEAISIMSRYTFWESQCLVKAIAGMKMLEKRHIEST
                     LYLGTAKDSHGELIAHAWLRSGSFYVTGSEGMEKFTVVGSFAKRLSEDTIKGE"
     gene            13911..15098
                     /locus_tag="III_RS09185"
                     /old_locus_tag="III_01824"
     CDS             13911..15098
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002014444.1"
                     /locus_tag="III_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01824"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_002167807.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.6e-67, bitscore:
                     224.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKDFGLNVEFMSKELKLLFTILKLQDDETLQTYSSEWFTDIDWE
                     VFLEQAMHHRVYPVIYQKLKQVDEERIPSHVVQTLNRKYRNNTFQMLYLSAEMERINKF
                     FNENEIRTMFLKGPVLSQDLYGDISLRTSCDLDVLIPVQKLEKVEKLLLEQGYVKDDYI
                     QTILSDWKWRHHHITFFHPTRRIKLEIHWRLNPGPGKEPGFEELWKRKRKSALTSNSVY
                     MLGKEDLFLFLVSHGARHGWSRLRWLVDIKKIVNQDLNWSEINKLMRKYQMFHLGGQAL
                     ILASQMLGARLDKRMMELVAKKRSKQLAQEALFYFKQMINLHTDPVPEEVLAYHSRHLF
                     SLMSNQQKILFIMSQLYPYPIDAKTLPLPKFLHFLYFPLRPFLCLWRKTKKLALS"
     gene            15110..16909
                     /locus_tag="III_RS09190"
                     /old_locus_tag="III_01825"
     CDS             15110..16909
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096316.1"
                     /locus_tag="III_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01825"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002128582.1"
                     /transl_table=11
                     /translation="MNHIIYFMKKLYSSAGKILYVNLFGMVLISLLEGIGIILLIPMIS
                     MAGIINIGEETAFIAPVYRFLQDFPKTTSLISILGIYILIVLGQNLLQRNITLRDARTQ
                     QAFVRELRIETYSMILKAKWSFFLEKRKTNLINILTTELARVSYGVNLILQLLAVILFT
                     FIQVGLAFLLSPQITIFVLVFGLLFLVASRAFIKKARILGGKTSKLAQDYLSGITDHFN
                     GIKDIKSNTLEASRLDWLQSITEKMSNEQMEYMRIRSNSQLFYKVSMAILIAFFILLSV
                     SIFKAQPTQLLLIILIFSRLWPRFMTIQSNLEQLAASIPAFKSLWDLQGECNEAIEMQD
                     IHQQKHIKPICIEQGIECKGIYFRYNKKEHLYALQNINVKIPINSMTAIVGHSGAGKST
                     LIDVLMGLIQPEKGQVLIDGTPLTSENLLSLRRAISYVPQDPFLFNASIRENLLMIEPN
                     ASEEQIWTALDFAAAAEFVRMLPKGLDTLIGDRGVRLSGGERQRLVLARAILRQPSILV
                     LDEATSALDTENEVKIQSAIERLKGTMTIVVIAHRLSTIRNADQVIVLGKGEIVQKGEF
                     NQLAKERKGVFRNLLGSQMEVGS"
     gene            17137..17460
                     /locus_tag="III_RS09195"
                     /old_locus_tag="III_01826"
     CDS             17137..17460
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016105867.1"
                     /locus_tag="III_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01826"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_002066545.1"
                     /transl_table=11
                     /translation="MNVQFKKGVLELCVLALVKRKDCYGYELVQQISNKFLISEGSVYP
                     LLRRLTKEGYFQTYLKESTEGPPRKYYQLTEQGEMQLTLLVTEWRDFAKGVQEIIEGVE
                     WDE"
     gene            17453..17995
                     /locus_tag="III_RS09200"
                     /old_locus_tag="III_01827"
     CDS             17453..17995
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031379.1"
                     /locus_tag="III_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01827"
                     /product="DUF1700 domain-containing protein"
                     /protein_id="WP_002128581.1"
                     /transl_table=11
                     /translation="MSKEQFLKELSSHLRKLPEEERQDILFDYEEHFQFGMEEGKTESE
                     IIKGLGSPKVIAKDLLAMYRFDEMKKDPSTSNVTRAVMAAVGLSLFNFIIVLGPLVAII
                     AFIFSFWVGGIASVVTPFFVIVKVFMGTFIWLDLFVSITFVGVGLLLCIVAYYSTKWFK
                     RLCVRYVVWNFKMIKGE"
     gene            17996..18799
                     /locus_tag="III_RS09205"
                     /old_locus_tag="III_01828"
     CDS             17996..18799
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016512438.1"
                     /locus_tag="III_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01828"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_002014437.1"
                     /transl_table=11
                     /translation="MMKKILLVAIACIIIGVIGISQTYEKAVQTAEKGDKEDVIKNETL
                     KNVEVKLDAGDIVVQKSPDSSFYVKQKGDVSKQEIRIAEDGDTLKIIGEIEKGVSFDFS
                     FYNFGFQTPTLTILVPERSYQEIKVNSSAGQIEISNVKSDRVSVETLAGEVDLKHVTAK
                     SVEGSTKAGEVNFKKVIGKVTAKTASGDIDIIDHDSKYDLEVSSTAGDVDITLLEKPQD
                     AVITGQTAAGDVTIFNEDNKNITIGNGSKKISGKTAAGDVTIETR"
     gene            complement(18903..19517)
                     /gene="lexA"
                     /locus_tag="III_RS09210"
                     /old_locus_tag="III_01829"
     CDS             complement(18903..19517)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413738.1"
                     /locus_tag="III_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01829"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_002087894.1"
                     /transl_table=11
                     /translation="MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHG
                     HLSRLEEKGYIRRDPTKPRAIEILGDNRTETQSVIQVPIIGKVTAGLPITAVESVEDHF
                     PLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATV
                     KRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH"
     misc_feature    19585..19598
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.42"
                     /tool="antismash"
     gene            19659..20315
                     /locus_tag="III_RS09215"
                     /old_locus_tag="III_01830"
     CDS             19659..20315
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016111193.1"
                     /locus_tag="III_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01830"
                     /product="recombinase family protein"
                     /protein_id="WP_002128580.1"
                     /transl_table=11
                     /translation="MNAIIYARVSTTKEEQETSLLRQKDELLHLAERYQMDVTKVIEEQ
                     ASGYTIERDGILEVLDTIRDEQVDVLLIQDETRLGRGNAKIALMHCLHKEGIKVYTHTH
                     SGELQLSDSDSMVLNIIGIVEEYQRKIHNLKIKRGMQRAVEKGFRPENNLKNRHLSVGR
                     EKKEVPIEEIVRLRRNELTFEEIAATLRGFGHDVSKATVHRRYVEYTKQLLDKED"
     gene            20361..20600
                     /locus_tag="III_RS09220"
                     /old_locus_tag="III_01831"
     CDS             20361..20600
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172959.1"
                     /locus_tag="III_RS09220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01831"
                     /product="DUF896 domain-containing protein"
                     /protein_id="WP_002014431.1"
                     /transl_table=11
                     /translation="MPSQELIERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNM
                     LNELKGIKVVNEEGTDVTPAKLKALKKQDNAKLN"
     gene            complement(20641..22224)
                     /locus_tag="III_RS09225"
                     /old_locus_tag="III_01832"
     CDS             complement(20641..22224)
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199635.1"
                     /locus_tag="III_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01832"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_002167808.1"
                     /transl_table=11
                     /translation="MNQNQIVTLNILLTSDVHGTVYPIHYQDNSKAEIGLAKISTLIKK
                     ERSQNANVLLIDNGDFIQGTPFTYHYATYEKDMENPMSLLANYLEYDIAIIGNHEFNYG
                     MDILNNAVATANSPYLSANILDKNRKEPYFGKPYIIKHIESNIKIAILGVTTHYIPHWE
                     QAHHIKDLQFEDAFETTKKWVSYIRKHEKPDLLVVAYHGGFERDLQTGVPTEVLTGENQ
                     GYAMCHEIEGIDILLTGHQHREIAHTVINGVTILQTGCNGHSVGKVTVTFEKAEQKWVK
                     KESYSELLPVQGIAADQDVLSLVANYEEKTQNWLDKPIGIIYGDMQISDAMQTRLQDHP
                     FIEFINKIQMDIANVSISCTSLFHNTSPGFPKHVTMRDIVSNYIYPNTLKVIRITGADI
                     KNALELSASYFTLKADGTIIVNPTYIEPKPQHYNYDMWEGISYVLNISKPIGERVESLQ
                     YKGAPLNMNEEYDVVMNNYRASGGGNFFMFQNKPVVKDIPTDMSELIANYILKHKRIEA
                     TKNENWKVIK"
     misc_feature    complement(22373..22389)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 28.44"
                     /tool="antismash"
     gene            22410..23348
                     /locus_tag="III_RS09230"
                     /old_locus_tag="III_01833"
     CDS             22410..23348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913375.1"
                     /locus_tag="III_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="III_01833"
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_002137777.1"
                     /transl_table=11
                     /translation="MLKKVFAMSTTVVLAAGLLSGCGTKESSASKNEDTKKGYVPKTLN
                     VQFVPSQNADTLEAKAKPLEKLLSDKLNIPVKVSISTNYNTIVEAMASKQVDVGFLPPT
                     AYVLAHEKKAANVILQAQRFGVDDETGAPTKDLVDVYKSEFVVKKDSNINSVKDLKGKK
                     IGYQDVTSSAGYVWPAAVLLKEGIDPLKDVKPVTLKGHDQSLIALLNGDVDAAVVFQDA
                     RNIVKKDYPNIFDQTKIVKFTEKIPNDTISVRSDLDAEWSKKLQDAFIEIGKNEEGHKI
                     IKEVYSHEGYVKSDDSKFDIVREYGKKVKTQ"
ORIGIN
        1 atatatgtac aaacatcttt aaaggaaggg tttggactta cagtaagtga agcaaaaata
       61 ttgaaaaaaa ctattgtgtg tactaacttt gctacggcaa aagaaattat taatcataat
      121 acagatggtt taatagtaga acatgatata gagagtatat acaatggcgt gagaagatat
      181 atagatgata atgattttag agaaaaaata ttcaaagaat taaactctat agaaccttat
      241 aattcggtaa atcaattgga gaaattctat gatttaatag aaaattgatg ggtgttgata
      301 ataaaatgaa aaaagtgttt gttgacattt atttgatgtt taattttgga gatgatttat
      361 ttttagatat ccttgtaaaa aaatatccaa attgttattt tacagtgaat catttaggtt
      421 caaattatga tcaatttatt tctcaatata ataatgtaag cagaagaaaa tatacactgc
      481 tgaataaaat tggacaacgt ctaaaattat cagataatat aactaactat gaaaaaatag
      541 cagaagaaca tgatgcatta ctatttatag gaggatctat ttttagagaa gaagcgtacc
      601 atagctcttt atatcgagat agaatgaaaa tggttatgga atttaagaga agaaaaaaat
      661 tagtatttat aataggagcg aattttggtc cttttaaaac ggaagaattt cttgatgact
      721 atagaaagtt ttttgagtta tgtgatgatg tttgttttag agatgtatat tcatatcaac
      781 tatttgaaga tttaccgcag gttaggtgtg catcagatat tgtttttcag atgaatacag
      841 atgaatatag gttagatttg tctgaagaaa gaattggatt ttcaataata gatgtcagac
      901 ataaacaagg gttaacccat tattataatg attatatacg tagtactata aagacaatag
      961 aattattagt gaacaaaggg aataaatgtt atttaatgtc gttttgtgaa caagagggtg
     1021 atttggatgt aattaacaca attcaatcac gtctttcctc taatgcatta gataatatag
     1081 taatttataa atataggggc aatttaaaag aggctatcga aacgatggcc tcttttaaat
     1141 tattaattgc agcgagattt catgctaata tattagcgtt attattgggt attggaatta
     1201 ttcctataat atatagtcag aaaaccatca atctcctgaa agatattgat tttaataaga
     1261 ctctaataga tatggaaaac ctgcaattac aatatgatga aaaggttata gatgcatcca
     1321 ttgattataa gtttaattta gaatctacaa taattaaggc aaagaagcag tttgaaaaat
     1381 taaatgattt tttaggtagt gaggcagtga aatcggaggg aatatgaaaa aaaatattat
     1441 ctttatgatc attaatatga atgtaggggg aaccgaaaag gcattactta atatgttatc
     1501 tgaaattcca aaagataagt atagtataac tattttaatg ttagagaaat acggtggttt
     1561 tttaaattct attcctagag aagttcacat taaatatttc gaagagtatg aagagataaa
     1621 agatatatta aatgagccgc ctcacataat ttttttgaat ttgctaagag aaggaaaaat
     1681 aattagaggt tcaagaataa tgcttttaca tcttttaacg aagtttataa aagatagaag
     1741 cctttttttt aaatatgtac tgcgagagta tcctatagtg gaaggtgaat atgatattgc
     1801 agtagcttat gctggtccaa tggatttcat aagttatttt gttattaata acataaaggc
     1861 gaaaaagaaa tttcaatgga ttcattttga tgtaacaaaa atcacattta atcaaatatt
     1921 ttcagataag ctatacaaaa aatttgatca tatatttgtt gtatctaatg aagcaaaata
     1981 taagctgctt agtatcattc cttctataaa aaagaaaaca gaggtatgtc ctaatatagt
     2041 ttctgcaaaa ttaatacaga atgaagcaaa agaggggaag agatttaacg ataatttttt
     2101 gggaataaga atattaacag ttggtagatt aacaaatgaa aaaggacaag atcttgctat
     2161 taaagtactg gcaagattaa tcaatgaggg atataaagtt agatggtatt gtgtgggaga
     2221 aggtggggct agaaaagaat acgaaaaatt aataacagaa tatggtttag aaagagattt
     2281 tattttgctg ggagagttat caaatccata tggctatatg gcaacttgtg atatatatgt
     2341 gcaaccatcc agatatgaag ggttttgtat aacgcttgct gaagcaaagt gtttacacaa
     2401 agcgattgta accacaaatt ttactggggc aaaagaacaa attaagaata gggaaacagg
     2461 aatgattgta aatattagtg aaagtgatat ttatgaaggt gtaaaaagtt tgatagataa
     2521 tcgcagtcta tgtgaagttt tttctgggaa tttggcaaat gaaaattttg ataaaacatt
     2581 agaattgaaa agaaattatg aattttttta aagataaaac atttaatttt gcaaggatag
     2641 taataagatg gaagtttaat atgagaggga aattttcaaa tgaaaagtca aattaaagca
     2701 ggagcaatat tatcatatgc ggctctagtt attaatagtt ctatttcact tttatatacc
     2761 cctattatgt taaagttact tggtcaatcg gaatatggtt tatacagttt agctacgtca
     2821 gttgcagggt atgtaggagt attaaatttt ggcttaggaa atgcagtaat tagatatacg
     2881 gcgaagtata gagcacttaa agatgaagag aattgttcac gcctgtatgg aatgtttagt
     2941 attatgtatg gggtattggg aggaatagca ttaattacag gtattatatt aacattaact
     3001 gcagatagta tattttcaag ttcattaaat gtggatgaaa taaataaact caaaacgtta
     3061 atggtgataa tggtaataaa tatatctata ggaataggct ttggcttttt tagtgttgta
     3121 gtattagcct atgaaaggtt tattttccaa aaaattctgg gcattattgg ggctatagta
     3181 gtgcctctta taatgttacc gcttcttata aagggctacg gatcagtgtc tatagcgata
     3241 gtaacgacat caataaattt tataataatt gcaattaata tgtattactg ttttaaagtg
     3301 ttaaggataa aaatagtatt taaaaaaata gaaattgggt tattgaagga aatcttagga
     3361 ttttcatctt taatattttt aaatttaata atagataaga tatattggtc cacagatcaa
     3421 gttatcttag gaatatatag tggagcagca gcaatttcca tatatactat aggagcatct
     3481 tttacaggtt atttctctgg gcttgctgca gctatatcga atgttttttt gagcagaatt
     3541 acagggatgg ttacaaaaaa ggcatctgat aaagaaatat cagatttatt tatcaagata
     3601 ggtaggattc aatatattat tttatcattt gttttaagtg gctttatcgt tttcggtcaa
     3661 gaatttattc atttatgggt tggaaaagaa tataatgagg cctttattat agctattata
     3721 atcttagttc cgatgattgt atcattagta caaagtattg gtggaattat actacaggca
     3781 aaaaatatgc aagggtttaa atcgattaca tatgtcgtaa catcttttgt taacgtagtt
     3841 ataagtataa tatttgttca atggtggggg gcaattggta gtgctttagg tacagctgta
     3901 gcatttacta tcgggaatat aatcattatg aatatttatt attggaagaa aatcaatata
     3961 gatataccaa ggttttggac aaatattact tgtatgagct tagcttttgg ggcaagttta
     4021 gtgtttggaa tgacattaaa tagatggata cttgcagaca aatggcagga attatttgtg
     4081 aagattattt tattttcaat cgtatatatt tgtttgatgt gggttacggg aatgaataaa
     4141 tatgaaaagg atacgtttag gcaggttatt caaaatatat tatacagatt taaaagaaag
     4201 aaagtcatac aagatacttc aagtaatacg gactgacaaa aaatatttag gtaatcgtga
     4261 ttgttaggaa aaaagttcac tccagtgtta ataatacaca tgaatctaga atgtacatgc
     4321 tttataaata tgagatagga acatttaagg tatttgtagc acattgcaat taacattttg
     4381 tgagtaattg tggggaattt taactataaa ttaacttgga aagaatatga tagatatcta
     4441 taccgttatt gatttaagtg aatatacttc tattaagaat ggaggtatgt tttaaataat
     4501 gagaaaaaat caagttagca gtaaaatacg agaagaatta aatgtattaa gccgaaatga
     4561 acttgttctt tcaattgata atagtggatt gtttgtgcgt atatttaatg gttttacaaa
     4621 aattaatcta aatacaaatg caaatgttaa tttttgtaat cgtttatgta agccagtgaa
     4681 gataggtgaa ataattgact atttatactg ttgaacttga acgttgggga ataaataatg
     4741 acggtacagc agctgtaaag acgacacagg gattaaatga tgcactttta tgggcgaata
     4801 aagaaggttt tcaaatagtg gttttaccaa aaggaaagta tcttatagag aaaacttctt
     4861 ctgtgaaact ttgtagtaat acaacgtata gattttatga atgtgtattt gagaaagaaa
     4921 ctaataatct tataaaatat aacatattgc tatgtgatgg aataaaaaat gtagaaataa
     4981 taggtgcaat agttaaagga gatagggaaa atcatgatta ttcaagtgga ggtacacatg
     5041 agtgggggca tggaattgaa tgtaaaaact catgttataa catttatgta aaaaactgtg
     5101 aagtaagtga gtgtactggg gatgggttgg taacatctat ggacttttca gcgataggtg
     5161 gaatgtcaca tccggatcac tttgcaaaag gtgacattga tagcaaagga aatttagaca
     5221 ttactaaagt taattataca acagtagtta aattttttga tattactgga gacatagtga
     5281 aatctgttgg gtatttttac tattcagggg atggttatgg tggatatgga agtggatgta
     5341 atttaaataa agttactata aaagtacatt tttatgcagg taatggttca tatttagggt
     5401 atagaaattt tagatcttat gaatttgtat atttagattc actgccgact ggtactacaa
     5461 aagtaaggtt ttcatttttg caaaattatg acttgatgaa tagtaatttg cactatgtaa
     5521 tgtgtgctaa tattccacaa tacgtatatt tttttggttg taaatcttat aaaaatagaa
     5581 gacttggagc ttcaataaat ggtggaagat ttatcacttt tgatgggtgt gaagttttca
     5641 ataatagtaa tgcaatgaat cgatcaatag ggtgtaatcc tggttatggg atagatattg
     5701 aagatggata tatgaataat caaaaaataa cgattagaaa ctctgatata tatgacaata
     5761 gagccggagc gtttgtgtgt attagtacta gaggtctata tttagaaagt aataaaatga
     5821 aaggaaatgt ctatctatct ggtagcggag atgactattt ttccataaat aatatgtatt
     5881 atggtgcaat tacggggaga tctataacta gtggaattga ggccgatgga acattttgta
     5941 catttagaaa tgatacaata ttcggtcaga attgtgggat tgttggaggg aatacaactt
     6001 tagaaaattg tgttttttca aaaagcacaa ttgctctaag tggcgagaca gtaaaaataa
     6061 tcaattgtaa atttactttt gatgatcctg ataaggatgg aattattgat tttaggagta
     6121 agtatttgga gatacgaaat tctttatttg atataagaag ggcgaaaagt atagcgacaa
     6181 ctggttatgg tcaaacggaa acggctatat tttcttctgt aaagtttttg acaaatgaat
     6241 gtaatggtgg acattatata ggagcaaaaa atttaattgt agaggattgc gagtttattc
     6301 atagtggtag aactgcaaac tatagtcgaa tgatggctgc tgaatctatg agagttgaga
     6361 aaactacttt taaaaatcaa tcttttaggt ttgatggtgg tgatatttat ggtattgaga
     6421 gcttggcgaa agacaaaggg tatattacac atgtttttag tagaaatcaa attatttggg
     6481 acgctcctta tggcctagcg gttcatgaag ctaggggagc gggagttgca tttatttata
     6541 taccaagaat agaaattacg gataataagt ttgaggtgaa tgggaaggat gtttctctcg
     6601 gttcattgca taccattagg atttttgtag aaaattattt gaagctctgt gacaatacga
     6661 ttatcacaaa aaatgatagc ggtataaata caacagggaa tattacaata gaaggtgtgt
     6721 atcgaaagca aaattcaaca cttcccgtgc caagaactgc tatcctagta caggataaca
     6781 agaaaatcaa ttctaatata acatttacaa acaatgtgaa caaccaattg gaaaagaata
     6841 tattaggtaa ccttccgcag tcttctttag tatcattaga acctaccttt ggaacgttta
     6901 gccgtggtga attactgtac aatgataccc caacagtagg tggatatatt ggttgggtct
     6961 gtataactgc tggcacagca aataaaaatt tttggatagc tgaaaaagaa tatcagataa
     7021 atagttttat aaatgccaat ggcaaagttt ataaatctgt agtggcaggt actagtggta
     7081 aaattgctcc ttcgcataca aatggtacta gtaaagatgg aaatatacta tgggaatacg
     7141 tggatgtctt agctgtgttt aaacgcttcg gcttaatctc tgactagaat agtttttata
     7201 ttctagtttt tttattggaa aagaattaga ttaattacca gtagaaaatt gtttgtccag
     7261 gcattttaaa taaaatgtga ggagtatgat tgtgaatgaa gcgacttttt gatgtgtgcg
     7321 tatccttatt gttattatta ttattttcga ttgttatatg catagtagct atattagtaa
     7381 gaataaaatt aggctctccc attttattta aacaaaagcg tccgggaatg aatggaattc
     7441 ctttttattt atataagttt cgcacaatga ctaatgaaat aggtggagat ggaaattgga
     7501 ttccagatga agtcagatta actaattttg ggaaaacgct tagaaaatat agtatagatg
     7561 agctacccca acttataaat gttataaaag gcgacttaag tttagtaggt ccacgcccat
     7621 tattgatgga atacttaccc ttatattcta gtaaacaggc taaaaggcat gatgtaaaac
     7681 caggaattac gggatgggca caaataaatg ggaggaattc aattacttgg gaagaaaagt
     7741 ttgaattaga tatatggtat gtagagaatc attctttttt attggatatg aaaattattg
     7801 tacttacaat aacgaaagta tttaaaccag aggggataaa tcatgtgggg catgtaacaa
     7861 tggagcgatt tactggaggg gatgtagaga taaaggggga tgggaaatga aaattttgat
     7921 aattgggtgt ggtggtcata gtaaggttgt gaaggatatc atcttatcaa atgaaggata
     7981 cgagatagtc ggttatttag atgatttata tacaggtata actattattg ataaccttta
     8041 ttttggtgca attgaagatg cacgggaaat tatcaacaat tttaatgatg taaagcttgt
     8101 tattgctata gggaataaca aaatgagaaa agaaatttcc ggaatattaa atcaaccggt
     8161 cggcatatat gctacattaa ttcataaaac agcaattata agtcctcatg cgcatatagg
     8221 gaacggaacg gtaattatgc cgaatgtggt tgttaatgct gatactatca ttggtaacca
     8281 tacgataata aatacgggct caataataga acatgataat ataattgatg attttgttca
     8341 catttcacca catgctacac ttacaggttc tatcacaata gaagaggggg cacatatagg
     8401 agcatcagct actataattc caggtgttaa aattgggagt tggtctattg ttggggcggg
     8461 ctctgttgta ataaatgact ttccatctaa ttgtactgct gttggcattc cagcgaaggt
     8521 tattaatgta gtaaattaag aggggatgaa gaataatgat aaaaaataag gagaaaatat
     8581 acctttcctc accgcacatg agtggaaatg aacaaaaata tattcaaaat gcatttgata
     8641 caaactggat tgcccctctt ggcccaaata ttgatggatt tgaaagagaa cttgcatctt
     8701 ttgtaggagt gaaaggtggg gctgcagtta gttcaggtac ggctgctatt catttagctt
     8761 tgcgattatt agatgtccaa aagggagata cagtgttttg ttcaagtttt acttttgtag
     8821 cgagtgcgaa tccgattgtt tatttgggag ctgaaccagt atttattgac tcagaaccgg
     8881 aaacatggaa tatgtcaccg aatgcattgg cacatgcatt gtatgaagct aataaagtgg
     8941 ggaaattacc aaaggctatc attcttgttc atttatatgg tcagagtgct aaactagatg
     9001 aaattctttc actttgtaat caatataatg ttcctatagt tgaggatgca gcagaatctc
     9061 ttggatctac atataaagga aaagcaagcg gtacatttgg gaggtttggg gtttattcat
     9121 ttaacggaaa taaaatcatt acaacttcag gtggtggaat gctagtttct aatgatgtag
     9181 aagcattaga aagagcgagg tttttagcga cacaagcaaa ggatccagct ccacattatg
     9241 agcatagtga gataggttac aattatagaa tgagtaatat attagctggt gttgggagag
     9301 ggcaattaga agtgttagaa gatagagtga ggactagaag gtgtatatat aaacggtatt
     9361 atgaagcact atctcacatg ccaggatttt attttatgcc tgaattagaa aatactcgct
     9421 ctaatcgttg gcttactaca ttgacaattg atgaaaagga atccgggatc tctattggga
     9481 aattgttgag aactttagca gaagagaata ttgaagcgcg tcctatgtgg aagccacttc
     9541 atatgcagtc gctctttaaa gagaagaagt attatccgca tagcaaaaat gaagatgtgt
     9601 cgcagtacct atttcaaagt gggatttgtt tgccttcagg atctaatatg ttagctgaag
     9661 atcaacaaag ggtaattcaa ggtattttaa aagctgtaga atggaagaat taaaagtaag
     9721 taaaagtgga attagatttg tatacgtacc accatttgtt ctttataatg aatttttaag
     9781 gggggtgttt ggggacattc agtttcaatt gacataaaaa agggataatt ataggctttt
     9841 aatatctata tcttagtctg aaagtaaatt taagcatgta attgagaaag taataaaaca
     9901 aataatttcg ttcgttaaaa agaatgataa agaggtatgt ttaacgaatt taatatgtaa
     9961 atagtatttg tagtaacttt tcatatatta ggaggaagaa atgagcgcta tagctggcat
    10021 tatccacttt actaatgagc ctgtatcaat tgagcacgga agagaagtaa tgagtcgttt
    10081 atacaaatat cctgccgatg atattcaaat atggcacaaa gaaaatgctt ttctaggatg
    10141 tcatgcacaa tggattacac cagagtcagt tggtgaacaa ttaccctttt ataattatga
    10201 aaagcaactg gcaattacag cagatgctat tattgataat cgtgatgagt tatttgaaaa
    10261 actacaagtg gattattcgg atagaaaaaa catgacagat agcgagttaa ttttactctc
    10321 ttatcagaaa tggggggaag cggctccaaa atatttggta ggcgattttg cctttatgat
    10381 ttgggatgag aaaaaacaaa ctctttttgg tgccagagat ttttcaggaa gtcggacact
    10441 ttatttttat cgtggtgagg aaaaatttac tttttgtact attataaatc cgttattttc
    10501 tctaccatat gttgagaaga aattgaataa gcagtggatt gctgaatttc tagctatacc
    10561 tgtaaatttc gaatcggtag atccacagtt aacagtttac aaatatatag aacaagtgcc
    10621 tccatcacac actattttgg taaaggaagg cgaagtgaag ttttcgcgat actatacacc
    10681 aactgttggg gaaatgctta atttaaaatc aaatgaagag tatgaagagg cgtttcgaga
    10741 ggtgtatcaa agtgcagtga aggcacgttt acgaacacat caccaagtag gagctcattt
    10801 gagcggaggg ctagactcag gttctgtcgt tagttttgct gcaagtgatt tacgggctga
    10861 aaataaaaaa ttacatacgt acagttatgt tccagtagaa ggatttgaag attggacaca
    10921 caaaggtaga atagctgacg aaagaccatt tattcaatcg actgtcgagc atgtagggaa
    10981 tatacaggat tattatttag aattgccgga gagaagccca ctatcggaaa ttgatgattg
    11041 gctggaaaca atggagatgc catataaatt ttttgagaat actttttggt tgagtggagt
    11101 ttatgaaaaa gcatctcaga atggaatagg agtacttctt agtggtcaaa gaggtaattg
    11161 gacagtatcg tggggaccta ttttagatta ccaggcaatg ttattgaaaa agctacattg
    11221 gattcgtttt tatcgtgaac tacatttata tagtagaaat ataggagtga aaaaatcacg
    11281 tgtttttgaa gtggtaagac gaaaggcatt tccatttttg catcagttac ttttttcagg
    11341 gaaacaagat gcaaattccg caataattaa tccggaattt gcaagggaaa tgaatgtttt
    11401 tgacagactc agagaacaag acatcgatat aacaggcacc tctatctcta atgcatatga
    11461 catgaaaaga gaacagtttg aaaaaccata ttattggagc ataaatggaa cgtatgaaac
    11521 gaaattatca ttacgttatg ctttatggga tcgtgatccc acaaatgact tacgattgat
    11581 tcaattttgt ttgtcagttc cagaagaaca gtatgttcaa aatggtttgg atcgagccct
    11641 gatccggaga gccacaaaga atttccttcc tgataaagta cgattgaatc aacgggttcg
    11701 aggtattcaa ggtgcagatg gtgtttaccg catggctcct ttttggaatg aatttattga
    11761 ggaagttgaa gaacttagtg tagatccagt aatttctgaa tttctaaatg tcgaggtaat
    11821 taagaaagct atctcaaaaa tttgtaaaga acctcgacca gaatatgcat ttgatttaga
    11881 ttttagaatt ttaatgcgta gcttaatctt ctatcgattt ataaaaaaag caatgtgaaa
    11941 ggaggtgata cgtatgaaaa aggaatggaa acaacctgta ttagaagtac ttaatattaa
    12001 tatgactatg gcggggcctg ggcataaata tccagatgct gttcaacctg acccagatga
    12061 tccagtgaag tacagttaag tcattggaaa aataaagctc ttatatagct ttattatata
    12121 agagctttca aaaaattgac aatgtggggg gataggatgt ttgattctat ggggaatgtg
    12181 ttatatcaag ccttcgggtt aaaaatagta agtgaaatcc cattacctga attgtctcag
    12241 ctgaatgaaa aaaaagagat ggcggatgtt caagttgaaa taactgattt gtcagaacag
    12301 tggggtgaat atagcgcaga aaagcaaaaa acgatagtag tggaggatga tatagttatg
    12361 tttcatgttc ctcaaactgc aatattcgct atacaatcag gtgagaaaat caccttttca
    12421 cctatggcaa atgcagaaga agataaaatt cgactatata ttttgggaac ttgtatgggg
    12481 gcgcttttaa tgcaacgtaa aatacttcca ttgcatggga gtgtaattgc tatagatggg
    12541 aaagcatatg cattaattgg tgattcagga gctggaaaat caacgttagc ctcggctttt
    12601 ttgaataaag gatataagct tttaagtgat gatgtagttg ctgtgtctct tttgaataaa
    12661 aatactgcaa tagttcatcc ttcttacgca caacaaaaat tatggcaaga gagcataaat
    12721 gagttaggaa tggaagtagc gcaatttagc cctttatttg aaagggaaac gaagtatgct
    12781 gttcctgtga attctcaatt ctttcctgat ccattacctc ttgctggtgt tattgaatta
    12841 gtaaaaacgc agggagaaga tattgagatg acccgtatag aagggctcgc acgcttgtat
    12901 aaattatacc gccatacttt taggaattct ttgatttcta aattaggatt gatggaatgg
    12961 cattttgaaa cttcatctaa tattgcaagt ggaatggaaa tatttcaagt aagccgcccg
    13021 gcttcaagat ttacagctca tgagcttgtg gaagttattt taaatactat acagaaaggg
    13081 agtatggttg atggttgtcc actcgagaaa aatatcatta gaacataacg ttgtccaaag
    13141 taagggtaat atagtaagcg atatggatgg agaaaaagtt atgttaaatg tccagaaagg
    13201 aaattactat aacttaggtg aaataggcgg agaaatatgg gagcttattg aaaagccaat
    13261 aataattaat cagcttgtta ctatgctagt atctaactat gatattgaac gaaaagattg
    13321 tgaagagcaa gttctttcct ttttagagtg tttgtttcaa gaagggttaa ttcaaataaa
    13381 agatcagcct aatagataga ttcgtaattt caaaagaact gttaggaagg gattaataaa
    13441 tattgtgaaa aggttaagga tgtttttatc actaaacatg aaaacaaagc tcttattttt
    13501 agaggctttt atttttttag gatgggcacg tgtactaaaa aatattacat tttccaaagt
    13561 tgcaccttct ttaggggatt acatgagtga aacctcaagt actcatattc aaccgcacgg
    13621 agatacgcta aaaaaggtgt ccgaagcaat ttctattatg agtcgttata ctttttggga
    13681 aagtcaatgt ctcgttaaag ctatagctgg gatgaaaatg ctcgaaaaac gtcacattga
    13741 gagtactctt tatttaggaa ctgctaagga tagtcatggt gaattaattg cgcatgcatg
    13801 gttacggagc ggttcttttt atgttactgg atcagaagga atggagaaat ttactgtcgt
    13861 tggatcattt gcaaagaggt taagtgagga cactattaaa ggagaataaa atggagaaag
    13921 attttggtct taatgtagag ttcatgtcta aggaattgaa acttcttttt acaattttga
    13981 agttacaaga tgacgaaaca ctgcaaactt atagtagtga atggttcaca gatattgatt
    14041 gggaggtttt tcttgagcaa gccatgcatc atcgtgttta tccggtgatt tatcaaaaac
    14101 ttaaacaggt agatgaggaa cgaattcctt cacatgttgt acaaacttta aatagaaaat
    14161 atagaaataa tacatttcaa atgctttatt taagtgctga aatggaacga ataaataaat
    14221 tttttaatga aaatgagatt cgtacgatgt ttctaaaagg acctgtacta tctcaggact
    14281 tatatggaga tatttcttta cgaacatctt gtgatttgga cgttctcatt cctgttcaaa
    14341 aattagaaaa agtagaaaaa ctacttttag agcaaggata tgtgaaagat gattatattc
    14401 aaacgatatt aagtgattgg aaatggaggc atcaccatat aacatttttc catccaacaa
    14461 ggcggatcaa acttgaaatt cattggaggt taaatcctgg accgggtaag gaacctgggt
    14521 ttgaagagct ttggaagcga aagagaaaaa gtgcacttac aagtaattcg gtatatatgt
    14581 taggaaagga agatttattt ttatttcttg tctctcatgg tgctagacat ggttggtcta
    14641 gattgcgctg gttagtggat ataaaaaaaa ttgtcaatca agatcttaac tggagtgaga
    14701 ttaacaaatt aatgagaaaa tatcaaatgt ttcatttagg aggacaagca ttaattttgg
    14761 catctcaaat gttaggtgca cgattagata agaggatgat ggaattagta gcgaaaaaac
    14821 gttcaaagca gttagctcaa gaagcgctgt tttatttcaa gcaaatgata aacttgcata
    14881 ccgatcctgt tcctgaagaa gtacttgctt atcatagtag gcatttattt tcactgatgt
    14941 ctaatcagca aaaaatttta tttattatga gccaactcta tccttatccg attgatgcaa
    15001 aaacattgcc gttacctaaa ttccttcatt ttttatattt tcctttacgt ccgtttctgt
    15061 gtctttggag gaaaacaaag aagcttgctt tgtcataggg ggaacatcga tgaatcatat
    15121 tatatatttt atgaagaaat tatattcttc tgcagggaaa attctgtatg tgaatttgtt
    15181 tggtatggtt ttaataagtt tacttgaagg gataggtatt attttattaa ttcctatgat
    15241 aagtatggct ggaataatta atataggtga ggagactgct tttattgcac ctgtttatag
    15301 atttttgcag gatttcccta aaacaacaag cctaatttct attttaggta tatatatact
    15361 aatagtgtta gggcaaaatc tattacaacg aaacataacg ctaagggatg cgagaacgca
    15421 acaagctttt gtacgagaat taagaataga aacatatagt atgattctaa aagcgaagtg
    15481 gagttttttt ttagagaaaa ggaaaacaaa tctaataaat atattaacta cagaattagc
    15541 tcgcgtaagt tatggggtta atttaatttt acaattgtta gctgttattc tgtttacatt
    15601 catacaggtg gggcttgcgt ttttattatc tccccaaata actatatttg ttttggtctt
    15661 tggcttatta ttcttagtag cttctcgtgc ttttataaaa aaagcacgaa tactaggcgg
    15721 taagacctcg aaattagcac aagactatct ttctggtata acagatcatt ttaatggaat
    15781 taaagatata aagagtaata ctttggaagc atcacgttta gattggttac aatctataac
    15841 agaaaagatg agtaatgaac aaatggagta tatgagaata aggtcgaact ctcaattgtt
    15901 ttataaagtt tcaatggcta ttttaattgc attttttata ttattatcag taagtatatt
    15961 taaagctcaa cccacccaat tactattaat catactcatc ttttcgagac tatggccacg
    16021 atttatgaca attcagtcaa atttagaaca gcttgctgca agcattcctg cttttaagtc
    16081 attatgggac ttacaagggg aatgtaatga agcaattgaa atgcaggata tacatcagca
    16141 aaaacatata aagccgattt gtatagagca gggtattgaa tgtaagggta tttattttcg
    16201 atataataag aaggagcatt tgtatgcact tcaaaatatt aatgtgaaaa taccaatcaa
    16261 tagtatgacg gctattgtgg gacattcggg agctgggaag agcacattaa tcgatgtttt
    16321 aatgggattg attcagccag agaaaggtca agtattaata gatggaactc ctcttacaag
    16381 tgaaaattta ttgtcattga gacgggctat tagttatgtg ccacaagatc cttttttatt
    16441 taatgcaagc ataagagaaa atttattgat gattgagccg aatgcgagtg aagaacaaat
    16501 ttggactgca ttagattttg cggcggcagc tgaatttgta cgaatgcttc caaaagggct
    16561 tgatactctc attggagatc gtggagtgag actttcaggt ggtgaacgtc aacgacttgt
    16621 actagctcga gctattttaa gacaaccatc cattttagta ttagatgaag ctacgagtgc
    16681 attagatact gaaaatgaag taaaaattca atcagcaata gaaaggttga aaggaacgat
    16741 gactattgtt gttattgcgc atcggttatc tacgatccgc aatgcagatc aagttattgt
    16801 tttaggaaaa ggtgagattg ttcaaaaagg tgaatttaat caattggcta aagagagaaa
    16861 aggtgtattt cgaaatttat tagggtcaca aatggaagtg ggttcataga ggagaaagat
    16921 tgaatgaaat cttgtattat tgtaattcga gttgaatgat agcccggata atggtcagtt
    16981 acaaaaggtc ttattcgggc ttttatattt gtgttttcta aatttaggga ataaatataa
    17041 ttcagtacct tgcaataaac aatactaagt ggtatattat ggataaaata gctaccgttt
    17101 attgaacagt actaaaatga gaaaggggga ttgtccttga acgttcagtt taaaaaaggt
    17161 gtgttagaac tgtgtgtatt ggcacttgta aaacgtaagg attgttatgg atatgaactt
    17221 gttcagcaaa tctctaataa atttttaata tcggaaggtt ctgtatatcc gttattacgt
    17281 cgtttaacga aagagggata ttttcaaacg tatttaaaag aatccacgga aggaccgccc
    17341 cgtaaatatt atcaactaac agagcaagga gagatgcaac ttactttatt agtaacagag
    17401 tggcgtgatt ttgctaaagg tgttcaagaa attattgaag gggtggaatg ggatgagtaa
    17461 agagcagttt cttaaagaat tatcaagtca tcttagaaag ttaccagaag aagagcgaca
    17521 agatatttta tttgattatg aagagcactt tcagtttggg atggaagagg ggaaaactga
    17581 atcagaaata ataaagggac ttggctctcc gaaagtaatt gcgaaagact tacttgcgat
    17641 gtatcgattt gatgaaatga aaaaagatcc gtcgacttca aatgtgacaa gagctgtcat
    17701 ggcagcggtt ggacttagtt tgtttaattt tattattgtg ttaggcccgt tagttgcaat
    17761 tatagctttt atattttcct tttgggtcgg tgggattgct agtgtagtga caccattttt
    17821 cgttattgta aaagtattta tgggcacttt tatatggttg gatcttttcg ttagtataac
    17881 gtttgtcgga gtaggtttgt tgttatgtat tgtagcttat tatagtacga agtggtttaa
    17941 aagattatgt gtacgctatg tagtctggaa cttcaaaatg ataaaagggg agtagatgat
    18001 gaaaaagata ttattagtag ctatcgcttg tatcattatt ggagtaatag ggatttcaca
    18061 aacatatgaa aaagcagtac aaactgcaga gaaaggagat aaagaggacg taattaaaaa
    18121 cgaaacgcta aaaaatgtag aagttaagtt agatgctgga gatattgttg tccaaaaatc
    18181 tcctgattcc tctttttatg taaagcaaaa aggagacgta agtaaacagg agattcgtat
    18241 tgctgaagat ggtgatacat taaaaatcat aggggaaata gaaaaaggtg tttcatttga
    18301 tttttcattt tacaatttcg gatttcaaac gcctacattg actatattag tacctgaacg
    18361 ttcttatcaa gagataaaag taaattcatc cgctggacaa atagaaataa gtaatgtgaa
    18421 aagtgaccgc gtaagtgttg aaacactcgc cggagaagtg gatttgaaac atgtaacagc
    18481 aaagagtgtg gaggggtcta caaaagctgg tgaggtgaat tttaaaaaag taatagggaa
    18541 agtaacagca aaaacggcta gtggggatat agatattatt gatcatgatt ctaaatatga
    18601 tttagaggta agttcaactg ctggagatgt agatattact ttattggaaa aaccacaaga
    18661 tgcagttata actgggcaaa ctgctgctgg agacgtgaca atttttaatg aagacaataa
    18721 aaatataacg attggtaatg gtagtaaaaa gattagcggt aaaaccgctg ctggagatgt
    18781 tactattgaa acgcgttaat aattaatgaa acgcattctt ttgaatgaac ggaaatctat
    18841 caaaatataa aaagaagata attacctata taaataaggg aattatcttc tttttattat
    18901 ttttaatgta aatcacgata tacgccaatt acttttccaa taactgacac ttgttttaaa
    18961 ataataggtt ctagtgaaga gttttccggt tgtagacgga aatgatcttt ttctttatag
    19021 aaacgtttaa cagttgcttc gttatcttct gttaaagcaa ctacaatttc accgttgtat
    19081 gcagactgtt gttggcgaac aacaactaaa tcaccatcaa agataccggc ttcaatcatg
    19141 ctatctccag aaatgcgtaa cataaacact tgatctgctc cagcaacgat actagctgga
    19201 agtgggaagt gatcttctac actttcgact gctgtaatcg gtaaaccggc agtaactttt
    19261 ccgatgattg gaacttgaat aacagattgt gtttccgttc ggttgtcacc taaaatttca
    19321 attgcgcgtg gttttgttgg atcgcgtcga atatatccct tttcttctag tcgtgataaa
    19381 tgtccgtgca ctgtagaact agaagcaagg ccgactgctt gaccgatttc acgtacggaa
    19441 ggtggatatc ctttttcttg tacttttagc ttaataaagt cgagaatgtc ttgctggcgt
    19501 ttcgttaact tttccatgtt ttctaacacc tcgttttctt tcatttttct tattattaag
    19561 tataacatgc gaaaaaacat tctacaaaca taagttcgaa cgaaaggcaa atttatgata
    19621 cactataagg aaaatatagt gagaaagaag ggttcaaaat gaatgcaatt atttatgcac
    19681 gtgtgagcac aacaaaagaa gaacaggaaa catcattatt gcgtcaaaaa gatgaattat
    19741 tgcatttagc tgagcgctat caaatggatg ttacaaaggt aattgaggag caggctagcg
    19801 gttatacaat tgaacgtgat ggcatattag aagtgctaga tacaattcga gatgaacaag
    19861 ttgatgtact acttatacaa gatgaaacgc gtcttggtag aggaaatgca aagattgcat
    19921 taatgcattg tttacataaa gaggggataa aagtttatac acacacacat agtggtgaat
    19981 tacagctttc agattctgat tcgatggtgc taaatataat tgggatcgtt gaagagtatc
    20041 aaagaaagat ccacaattta aaaattaaac gtggcatgca aagagcagtg gagaaaggat
    20101 ttcgtccaga aaataatttg aaaaatcgtc atttaagcgt aggacgtgag aaaaaagaag
    20161 tgccaattga ggaaattgta cgtttgcgcc ggaatgaatt aacttttgaa gaaattgcag
    20221 caacacttcg tggttttggt catgatgttt caaaagcaac tgtacatcga aggtatgtag
    20281 aatatacaaa gcaattgctt gataaagagg actaactatt gtatgataat aatcagtttt
    20341 gagtagaagg gggattcgag atgccaagtc aagaactcat tgaacgcatt aacttcttag
    20401 cgaaaaaagc aaaagctgaa ggcttaactg aagaagaaca acgtgagcgc caatcgcttc
    20461 gtgaacaata tttaaaagga tttcgtcaaa atatgttaaa cgaattaaaa ggaattaaag
    20521 tcgttaacga agaaggcacg gacgttacac cggcgaaatt aaaagcttta aaaaagcagg
    20581 ataatgcaaa attaaattaa aagatgggca tagcccatct ttttttattt gttaaaattg
    20641 ttatttaata actttccagt tttcattttt cgttgcttct atccttttat gcttcaatat
    20701 atagttagcg ataagttcag acatatctgt tggtatgtct tttactactg gtttattttg
    20761 aaacataaag aagttcccgc caccgcttgc acgataatta ttcataacaa cgtcatattc
    20821 ttcattcata ttaagaggag cgcctttata ctgcaaagac tctactctct ctccaattgg
    20881 ttttgaaatg tttaatacat acgaaatccc ttcccacata tcgtaattat agtgttgtgg
    20941 ttttggttct atataggtag ggtttacgat gatggttcca tctgctttta atgtgaaata
    21001 agaagcagag agttcgagag cattttttat atccgctccg gttattctaa ttacttttaa
    21061 tgtatttgga taaatataat tagaaacgat gtcacgcatt gttacatgtt tagggaaacc
    21121 tggagatgta ttatgaaaca aacttgtaca agaaattgaa acattagcta tatccatctg
    21181 tattttattt atgaattcaa taaaaggatg gtcttgcaaa cgtgtttgca tagcatcgga
    21241 aatttgcata tccccataaa ttattccaat aggtttatca agccaatttt gtgttttctc
    21301 ttcataattg gcaaccaagg aaagaacatc ttggtctgcc gcaattcctt gtacgggcaa
    21361 taactctgaa taactctctt ttttcaccca tttttgttct gctttttcga atgttactgt
    21421 tacttttcca actgagtgtc cattgcatcc ggtctgtaaa attgttacac cattaatcac
    21481 ggtgtgagcg atttctcggt gttggtggcc tgttagtaaa atatctatgc cttcaatttc
    21541 atggcacatt gcatatcctt ggttttcacc tgttaaaact tcagtcggta ctccggtttg
    21601 taaatcacgt tcaaatcccc cgtgataggc tacgactagt aaatctggtt tttcatgttt
    21661 acggatgtaa gaaacccatt tttttgttgt ttcaaatgca tcttcaaatt gtaaatcttt
    21721 aatatgatgt gcttgttccc aatgggggat gtaatgcgtt gtcaccccta aaatagcaat
    21781 ttttatgttt gattcaatat gttttattat atatggtttt ccgaaataag gttcttttct
    21841 gtttttatct aaaatgtttg ctgatagata aggggaattt gcagtagcca cagcattatt
    21901 taatatatcc attccgtaat taaattcatg atttccgata attgcaatgt catactctaa
    21961 gtagttggct aataaggaca ttgggttttc catatctttt tcgtatgtag cgtaatgata
    22021 agtaaatggt gttccttgaa tgaagtcccc gttatcaatc agaagaacgt ttgcattttg
    22081 agaacgttct ttttttatga gagtagaaat tttagctaaa ccaatttctg ctttggagtt
    22141 atcttggtag tgaattggat acacagtacc atgtacatcg cttgttaata aaatatttaa
    22201 agttacaatt tgattttgat tcaacgccat tcaccttttc tatagttatc tttcaattaa
    22261 tcatatcaaa tatatgaaaa gaattttaat gtgaatgtat agaatgtgta aagattctgt
    22321 aaataagcaa ttatttgtaa aaatatgtga tatatttctt catgtttatg gaaggttatt
    22381 ttataacaac gaaaaatgga ggcattaaca tgttgaaaaa agtttttgca atgagcacaa
    22441 cagttgtact agcagcggga ttattaagtg gatgtggaac gaaggaatca agtgcaagta
    22501 aaaatgaaga tacgaaaaaa ggttatgtac cgaagacact aaatgttcaa tttgttcctt
    22561 ctcaaaatgc agatacgtta gaggcgaagg caaaaccatt ggaaaagcta ttaagtgata
    22621 aattaaacat tccggtaaaa gttagtattt caacgaatta caatacaatt gtagaagcga
    22681 tggcatctaa gcaagtagat gtaggctttt tacctccaac agcgtatgtg ttagcgcatg
    22741 agaaaaaggc tgcaaacgta attttacagg cgcaacgttt tggggtagat gatgaaactg
    22801 gagctcccac aaaggattta gtagatgttt ataaatcaga gtttgttgtt aagaaagatt
    22861 ctaatattaa tagtgtaaaa gatttaaaag gtaaaaaaat tggctatcaa gatgtaacat
    22921 catcagcggg ttatgtatgg cctgcggctg tattgttaaa agagggaatc gatccgttga
    22981 aagatgtgaa acctgttaca ttaaaaggtc atgatcagtc acttattgct cttttaaatg
    23041 gtgatgtaga tgcagctgtt gtattccaag atgctcgtaa tattgtaaaa aaagattatc
    23101 cgaatatatt cgatcaaacg aaaatagtaa aatttacgga gaaaattcca aacgatacga
    23161 tttctgtacg ttctgattta gatgcagagt ggagcaagaa attacaggat gctttcattg
    23221 aaataggaaa gaatgaggaa gggcacaaaa tcattaaaga agtatactca catgaaggat
    23281 acgttaaatc tgatgatagt aaatttgata tcgttcgtga atatggaaag aaagtgaaaa
    23341 cgcaataata catatggaaa tggcgactaa ctggaaagtg tgtgatttca gttagtttgc
    23401 cgtttttcag ttattgataa tacatagaag gtaggtaaga tgtgtgatag agtttcgaaa
    23461 tgtttccaaa gtgtatccaa atggtacaaa aggattgaat aatataaact tgaaaattca
    23521 aaaaggtgag tttgttgtaa tggtcgggct atccggtgct ggaaaatcaa cacttctcag
    23581 atcggtaaat cgccttcatg aaatcacaga aggagaaatc attattgaag gggagtctat
    23641 tactgctgca aaaggaaaag gattacgacg catgcgccga gatattggta tgatttttca
    23701 aagctttaac cttgtgaagc gatcaacggt actgaagaat gtattagctg ggcgggttgg
    23761 atatcattct acattgcgta caacgttagg tctgtttccg aaagaggatg tggagcttgc
    23821 attccaggcg ctgaatagag tgaatatctc agaaaaagca tatgcacgag ctgatgaatt
    23881 atcaggggga caacagcaac gtgtatcaa
//
