LOCUS       NC_016109              22482 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Kitasatospora setae KM-6054, complete sequence.
ACCESSION   NC_016109
VERSION     NC_016109.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora setae KM-6054
  ORGANISM  Kitasatospora setae KM-6054
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1
  AUTHORS   Ichikawa,N., Oguchi,A., Ikeda,H., Ishikawa,J., Kitani,S.,
            Watanabe,Y., Nakamura,S., Katano,Y., Kishi,E., Sasagawa,M.,
            Ankai,A., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Nihira,T., Horinouchi,S., Ohnishi,Y., Hayakawa,M.,
            Kuzuyama,T., Arisawa,A., Nomoto,F., Miura,H., Takahashi,Y. and
            Fujita,N.
  TITLE     Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
            snapshot of the family Streptomycetaceae
  JOURNAL   DNA Res 17 (6), 393-406 (2010)
   PUBMED   21059706
  REMARK    DOI:10.1093/dnares/dsq026
REFERENCE   2  (bases 1 to 8783278)
  AUTHORS   Ichikawa,N., Watanabe,Y., Nakamura,S., Katano,Y., Oguchi,A.,
            Ankai,A., Yashiro,I., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Ikeda,H., Ishikawa,J., Horinouchi,S., Ohnishi,Y.,
            Hayakawa,M., Nihira,T., Kitani,S., Kuzuyama,T., Arisawa,A.,
            Nomoto,F., Miura,H., Takahashi,Y. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2009) Contact:Director-General Department of
            Biotechnology National Institute of Technology and Evaluation, NITE
            Genome Analysis Center (NGAC), Department of Biotechnology; 2-49-10
            Nishihara, Shibuya-ku, Tokyo 151-0066, Japan URL
            :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000269985.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:32:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,713
            CDSs (total)                      :: 7,605
            Genes (coding)                    :: 7,487
            CDSs (with protein)               :: 7,487
            Genes (RNA)                       :: 108
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 25 of 118
            Pseudo Genes (incomplete)         :: 95 of 118
            Pseudo Genes (internal stop)      :: 9 of 118
            Pseudo Genes (multiple problems)  :: 11 of 118
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:33:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5196489
            Orig. end                         :: 5218971
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP010968.1.
            'Otoguro, M. is at NITE Biological Resource Center (NBRC). Ikeda,
            H., Miura, H. and Takahashi Y. are at Kitasato Institute for Life
            Science. Ishikawa, J. is at National Institute of Infectious
            Diseases. Horinouchi, S., Ohnishi, Y. and Kuzuyama, T. are at The
            University of Tokyo. Hayakawa, M. is at University of Yamanashi.
            Nihira, T. and Kitani, S. are at Osaka University. Arisawa A. is at
            Mercian Corp. Nomoto F. is at Nagase & Co. Ltd. The other authors
            are at NITE Genome Analysis Center (NGAC).
            Please visit our web site. URL:http://www.bio.nite.go.jp/
            DOGAN ; Database of Genomes Analyzed at NITE. The database contains
            genome sequence data, physical maps and the genomic and proteomic
            data of the microorganisms analyzed.
            URL:http://www.bio.nite.go.jp/dogan/Top
            The microbial strain and microbial genomic DNA clones used for the
            sequencing project are available through the NBRC.
            URL:http://www.nbrc.nite.go.jp/e/index.html.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22482
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="28"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22482
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22482
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12482](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12482)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(14..24)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            complement(1839..2693)
                     /locus_tag="KSE_RS23160"
                     /old_locus_tag="KSE_46950"
     CDS             complement(1839..2693)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_46950"
                     /product="hypothetical protein"
                     /protein_id="WP_014137775.1"
                     /transl_table=11
                     /translation="MSAVGLGPREARHWLETELGRLGYDRKRPEYTEDGRHFRPVLGTP
                     GWCMVIWAPPETWPPGALACWRVVWHPAAEFSRDSRKEVPKGAAGHWEESTAAVLAALR
                     SLGLQAAVTGPHRGSERFGSRAFLAWELPPGAVADWPPAGAWDGVPPTRPNFIDGWPQW
                     AEGPAPGDEVAGALRAVAERRRGAGVADIGRRSVLDTDSPLWPPGAHMSAHVTWWPDPE
                     FARAYGEPLPPAAAEHWRAGVGQLLGDLAAIGRYQFRTAWEHPGARHDGAGVIVWRGPS
                     RPS"
     gene            complement(2690..3166)
                     /locus_tag="KSE_RS23165"
                     /old_locus_tag="KSE_46960"
     CDS             complement(2690..3166)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.4"
                     /locus_tag="KSE_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_46960"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_014137776.1"
                     /transl_table=11
                     /translation="MHPTPDEPVRLDAAAVAAALDRVDLLTVGAQVGGPPPEDGMVELL
                     DELVGHLALLVAEVDAAYGALPELSAVRGSVEAALHGGRRLLGNPPSDLFAGVVLFGVY
                     CRVLSTLRWVHPRLEEDRLPGVPYGGIRRGGGPPGRHRHAQMRAPRGRRPGAGR"
     gene            complement(3268..3777)
                     /locus_tag="KSE_RS23170"
                     /old_locus_tag="KSE_46970"
     CDS             complement(3268..3777)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="KSE_RS23170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_46970"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_014137777.1"
                     /transl_table=11
                     /translation="MTHAEIPHDGQPRRRVGCLTLILDQEDRVLFSVTTYKQRPILPGG
                     AAGKDERFDRAAARELREETGLVRRLSHFFAVDQTPENGETGSNEGLNLVFDGGVITDE
                     ELAALAVPEAAAGEIAGHVWLREDEFDGALLPATAARVRAVLAARKARQLLPLLHHGVP
                     VSELPA"
     gene            complement(3941..4516)
                     /locus_tag="KSE_RS23175"
                     /old_locus_tag="KSE_46980"
     CDS             complement(3941..4516)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="KSE_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_46980"
                     /product="ATP-binding protein"
                     /protein_id="WP_014137778.1"
                     /transl_table=11
                     /translation="MKADPGRANPELTARMTVEATAAELESRLHAVPVVRHRARTVLLE
                     EWGLAKGDVLDALQMLSELVANAARHSPPGMHHVALHLAPDGTALVMEVHDLSRAVPYV
                     PAGAREDGVRENGRGLLIVADLAEGWGWVPTSGGKKVWAQLRLAVPVQPPHPRRAVQGV
                     PEAVLRRAAVTAGLQVSRLCAVRRPRVA"
     gene            complement(4513..4920)
                     /locus_tag="KSE_RS23180"
                     /old_locus_tag="KSE_46990"
     CDS             complement(4513..4920)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_46990"
                     /product="hypothetical protein"
                     /protein_id="WP_033260339.1"
                     /transl_table=11
                     /translation="MRSALVYLCTDDKVSRPLMAGWCEQRAAAEGIPVTETVLDTDGLL
                     PPAERPGWQHVMALVAGGHVVMVVTLDRTMLAVGRKDWDRLAASVAQHGAVLVTHRTPG
                     PSFPPTDGAQQLPPAPAAPPAVELVDAGAQR"
     misc_feature    complement(5141..5161)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.04"
                     /tool="antismash"
     gene            5171..6454
                     /locus_tag="KSE_RS23185"
                     /old_locus_tag="KSE_47000"
     CDS             5171..6454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137780.1"
                     /locus_tag="KSE_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47000"
                     /product="hypothetical protein"
                     /protein_id="WP_014137780.1"
                     /transl_table=11
                     /translation="MGDNLEIQRRMLELGFSQVELAHRVNDVIKTLTGRYGTCSERTVR
                     DWVRGKVTWPRGLQRRSLEEVFDCTAEELGFQPRGATPAPPPTENDVRRQTFLKGIAAT
                     ATTAAGLTPSPATAAPRTTIGTSDVIRLRAGLETLDALDDHRGGHGALEKAALAGAAEV
                     MALQRTGSASERIRSRLFSVAADYTAVAAWSCIDARDLDQAQKHLDTCMRLAGLARDPV
                     AVFRTWNMIAMLANQLGNYPDAVAAARAAQRTGITRRDPAFASLAHARTAIGSAGLNDR
                     QSALRSIGLAADSLGRARGDQPCPSWFAFYGAAELQALTSIVQDRLGDAVSAESASHQA
                     LALLPAQFRRNRALATARLALTQLHQDEVDLAVHTASSVFDVMAGDPLPGRMRTLLGDF
                     HRELLTLSTNAPAAQEWGDRYRAEWSRT"
     misc_feature    complement(5177..5191)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.87"
                     /tool="antismash"
     gene            6439..6972
                     /locus_tag="KSE_RS23190"
                     /old_locus_tag="KSE_47010"
     CDS             6439..6972
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137781.1"
                     /locus_tag="KSE_RS23190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47010"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_014137781.1"
                     /transl_table=11
                     /translation="MEPNVTDATHLRHYRADDVNDPFRQMLIAIHAEVYADVMDDEFNQ
                     RFPWFVNHWSSMEGFSCVVAYDGQEPIGFIYGAPLSAGREWWREHIVPAPEDSSTFAVS
                     ELMVRPAWQKQGHSTRLHDELVADRPEALAVLLVDTEHPKVQALYESWGYAKVGDRRPF
                     ADSPLYAVMVRELS"
     gene            6974..7519
                     /locus_tag="KSE_RS23195"
                     /old_locus_tag="KSE_47020"
     CDS             6974..7519
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137769.1"
                     /locus_tag="KSE_RS23195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47020"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_051055351.1"
                     /transl_table=11
                     /translation="MALRSMAVAHYTAEDLPEIEPVLLDLYDRIYAEEKAGDPFFSMEA
                     FTGRLHRQAAAPRWGCALGEVDGRPVGYAYGFARTADYRWGGLIETEPGADLAETDSRT
                     FAFCEIMVLPESRGTGIAHTLHEELLSHRPEERVHLLVEEDHPRVRALYERWGYTKMGI
                     IQHPGSPRYVSMLRPVAL"
     gene            complement(8420..8782)
                     /locus_tag="KSE_RS23200"
                     /old_locus_tag="KSE_47040"
     CDS             complement(8420..8782)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47040"
                     /product="hypothetical protein"
                     /protein_id="WP_014137783.1"
                     /transl_table=11
                     /translation="MSTTAPATCRIAADRAAADGGLCKPAIPSRSPALAEGDSLAYLIL
                     TRREGEGPVRFELGATGRGPAGQDLADRLCKQIRAWDGDREARPTIKLYPAGTPDSKIG
                     NGYIIDKPGCRVAISY"
     gene            complement(8862..10004)
                     /locus_tag="KSE_RS23205"
                     /old_locus_tag="KSE_47050"
     CDS             complement(8862..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013315.5"
                     /locus_tag="KSE_RS23205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47050"
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="WP_014137784.1"
                     /sec_met_domain="PCMT (E-value: 4.2e-33, bitscore: 113.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTAPTAWQQAADALVQDLRGKGAVRTDAVARALREVPRHLFVS
                     GHYGPGGFTAVDPEQPTPETLAIVYSDRGLTTHVPDDTSGTSSSTSQPSIVAKMLEAAD
                     LHPGMDVLEIGAGTGWNSALIAHITGGPVTAVEHSEPVATEARAALERAAVPGVRVHTG
                     DGYLGYPSNGYFDRIIVTCGIAGIPPAWLDQLTPNGMILAPLAHGGVHPLTRVYAPGPG
                     GTPTGRLVTMADFMTAAGPLYGGRPVPPSSRGSYLPVPAGRVAGPFPGGLDRDAFADLC
                     MFLAGHDPRVTCAASEDGTYGGCAVVTEDETAGVFVQPDGLYSAGSDAETAALVRTTAD
                     RAAAWDVSGRPPLIAWSCSMQLAGPSSDPLLVPGRWHIAE"
     gene            complement(10001..10432)
                     /locus_tag="KSE_RS23210"
                     /old_locus_tag="KSE_47060"
     CDS             complement(10001..10432)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="KSE_RS23210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47060"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_051055353.1"
                     /sec_met_domain="PF13471 (E-value: 7.5e-17, bitscore: 60.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTALPSRVRLRPGERLVALASGLAAVWTTRGGRPDGRLHTVLNR
                     ALRGRLPPSTPEQAEHAVQAVTTAFLWLGGTTACLPRSVAAVLYCRFHGHAPTLVIGLR
                     PGTADVHAWIEAAGEPAAEPFDPRPAYLPVTVYRQGAAL"
     gene            complement(10435..10698)
                     /locus_tag="KSE_RS23215"
                     /old_locus_tag="KSE_47070"
     CDS             complement(10435..10698)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="KSE_RS23215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47070"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_014137786.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-08,
                     bitscore: 33.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.9e-08, bitscore: 31.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLSPGARLLTAADTGRGTLVTAAGDVWTLNATAVTVLQAMERG
                     GGAEAAAVALLARFPEQGAAAVRRDVADVLDALRRHGVVTDR"
     aSDomain        complement(10444..10662)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_KSE_RS23215_Stand_Alone_Lasso_RRE.1"
                     /evalue="4.80E-11"
                     /identifier="RREFam002.1"
                     /label="KSE_RS23215"
                     /locus_tag="KSE_RS23215"
                     /protein_end="85"
                     /protein_start="12"
                     /score="33.5"
                     /tool="antismash"
                     /translation="AADTGRGTLVTAAGDVWTLNATAVTVLQAMERGGGAEAAAVALLA
                     RFPEQGAAAVRRDVADVLDALRRHGVVT"
     gene            complement(10692..12482)
                     /locus_tag="KSE_RS23220"
                     /old_locus_tag="KSE_47080"
     CDS             complement(10692..12482)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.5"
                     /locus_tag="KSE_RS23220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47080"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_081539582.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.6e-34, bitscore:
                     118.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFGQWFTVLPGKPPAARPAAALVQAGAEVLAWADDQPWIVGRAGS
                     DRVTSTSAGRYRVAVIGDHRVEAAELADRAGALRPSGRWERLLELPGSYHLVVLDGSVT
                     WLFGDSAGLRPVFATVQSGAVFLGSRARPLAALGHRHLDVDHLAVQLLAPAPPLALAES
                     GTSPYRGVSELPPGTAARIDASGALRTEAWWTVPDDDVGAADGAVLLREALRGAVAVRC
                     EADAPVAVELSGGLDSSALSALAFERVGPRTLNLSRASADPANDDLRWARLVTAAQPGA
                     GHRVLAVGEVPGQFDGWQQALPLDSPGPTAVSPARAAFLWQQALDGGARVLLSGKGGDE
                     VLLPPLTYLGSAPRLLARQHRRGWTALRGTRVRDVRAEAAFPGPYRAAVAGALDGAMDW
                     ESGPWVPRWLTVTARRRLEERLRDAAAGARPLHDRPHQHTAVAALRAMARWNRLQADAA
                     GTLGLRMAYPFQDRAVLDAALSVRGHHRSSPFAFKPLLTGALRDVLPAEVLTRRTKGGY
                     NADDRAAARRHRRGLASLLLRDSALADHGLVDPAALAPAVREWAAAEGTDELTLLMTLN
                     AEVWARTAEGRPLTEGAVLC"
     misc_feature    12469..12487
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(12483..12647)
                     /locus_tag="KSE_RS42970"
                     /old_locus_tag="KSE_47090"
     CDS             complement(12483..12647)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS42970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47090"
                     /product="hypothetical protein"
                     /protein_id="WP_014137788.1"
                     /transl_table=11
                     /translation="METKQSVEETDGHEEYEAPTATLAGTVGSLAAGSYSSGISDDGDY
                     YTTKYQQQG"
     misc_feature    12694..12709
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    12694..12710
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.79"
                     /tool="antismash"
     gene            complement(12837..13703)
                     /locus_tag="KSE_RS23225"
                     /old_locus_tag="KSE_47100"
     CDS             complement(12837..13703)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47100"
                     /product="hypothetical protein"
                     /protein_id="WP_014137789.1"
                     /transl_table=11
                     /translation="MTSFLISNEAGSAGRAFTVRAEEALYAAAPRIVELSALPLPDEVT
                     VRLVRPGAVPGITRGHFTIVGRMVSAEFEAEEHRAAALKLAATQGAITGLMTRLCWPLI
                     GGQMVLGPVGPELLVVHRMHAGNRTSQRALTQTLGHELVHAAEFLRFPGLVPMWVRQMV
                     EARIGRRPARDVLPVPEVSEGHAMWVHRRLVAELGGVEDHFPGDPKAKLRFRALRRVAE
                     FLPIVPDRSLYLRGQQFMSALHDAGGPAMLSSIFDGEDTVPTSAELDSPALWLARHRAE
                     ASPPPAA"
     gene            complement(13944..14198)
                     /locus_tag="KSE_RS23230"
     CDS             complement(13944..14198)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_033260148.1"
                     /transl_table=11
                     /translation="MSTAVFDAAARYAASTGAEAAIQRVGCGCYRVAAPANPDSLADCW
                     AVLGLARAAGSCITARTWTGGGSIAAIIHEPHCRAGRPA"
     gene            complement(14195..14356)
                     /locus_tag="KSE_RS42975"
     CDS             complement(14195..14356)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS42975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157850101.1"
                     /transl_table=11
                     /translation="MASSPSQRPQQDARYRPCGACARCRTGVGRDQNPAVSDCWDDYLT
                     AATTQRSA"
     gene            complement(14346..14906)
                     /locus_tag="KSE_RS38755"
                     /old_locus_tag="KSE_47110"
     CDS             complement(14346..14906)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS38755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47110"
                     /product="hypothetical protein"
                     /protein_id="WP_014137790.1"
                     /transl_table=11
                     /translation="MTEAGIHWDAVAVQQEPGLAALSVLDQETGHRTGPVIWDTRNSTL
                     YFLVPAASAAAAADPALGTRPLSRGTYIGVPGVDRVDPTGLCWIAPPSPTDLDQLVDPL
                     RLAAVLRHLATARWVTRAVAGGREVDILASDEQLAGRACIVCRTTRRPLHPDGVVTLQA
                     GAGVVRDYDTVVCTRDLEAGHGQ"
     gene            complement(15046..16302)
                     /locus_tag="KSE_RS23240"
                     /old_locus_tag="KSE_47120"
     CDS             complement(15046..16302)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024835.5"
                     /locus_tag="KSE_RS23240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47120"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_081539584.1"
                     /transl_table=11
                     /translation="MGPCNTAAPAGGNSPKRSRARARQRYRRDVDQDFGRRLQQARKMR
                     HMTQSQLAQDAGVSTSYIGAIEQGARTPGDGVVAALARAMGMRVPDLLGQPRTDELRRD
                     QLAALVQPIREALDLYDLGADPDVAPRDQAALAADTDRLCALIRASDLRAAAAELPGLI
                     VETTTAAHTHQTRRLWQALAMQYRTAYDVASKTGYPDLASIALDRMGWAAERASDAAVA
                     GLRMYNRAMLYLRSGQARTGIRIAALARATVEQADPGLDRRAVTGQLYLASAVLSAGAG
                     QRDDVEEYLAAADRYAAATGETTTLWMSFGPTNAAAHRASCYVDQGMYREALEVARRIE
                     IPATWATSRAAHHHAEMARAHLWLGRPEEAFARLQTARQLAPQQIRHSAKVKDAATGIV
                     RAHRRPPEQVVQFAQWAGI"
     gene            16301..16840
                     /locus_tag="KSE_RS23245"
                     /old_locus_tag="KSE_47130"
     CDS             16301..16840
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137792.1"
                     /locus_tag="KSE_RS23245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47130"
                     /product="flavoprotein"
                     /protein_id="WP_014137792.1"
                     /sec_met_domain="Flavoprotein (E-value: 5.8e-10, bitscore:
                     37.9, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNPRPVVYLFASAAPPALELPDVVRRARGRGWDVAVGLTPTARD
                     WLDERVPELEELTGHPVKTAYRRPGQPDVLPPADAVLFAPATFNSVNSLAAGITSSWVV
                     GFAAEAPGKRIPVVVMPCINSALVQHPQFDRSVAVLREAGMRVLYGPPDGFVPNRPGER
                     LPYPWERALAAVEQAV"
     gene            complement(16913..17092)
                     /locus_tag="KSE_RS42305"
     CDS             complement(16913..17092)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS42305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148283149.1"
                     /transl_table=11
                     /translation="MPEHAVEDGHRVCSRGDGLRISCRVCAELWVRVPIASAFGEMARM
                     LAMMPPPPDSFVLA"
     misc_feature    complement(17328..17343)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.67"
                     /tool="antismash"
     gene            complement(17641..18021)
                     /locus_tag="KSE_RS23255"
                     /old_locus_tag="KSE_47150"
     CDS             complement(17641..18021)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47150"
                     /product="hypothetical protein"
                     /protein_id="WP_014137794.1"
                     /transl_table=11
                     /translation="MTSLHLGTEDFQGVVFTHDGRVRLDLTDGGLDRLAGVVRQFELAK
                     REPEQRAMWLRNISDVELVELATGRWGGPEQDVLDEAVRHLQAMAEKLHPALGAVRAAG
                     LIDQAAGEQPADGSTETAGSGE"
     gene            18288..19193
                     /locus_tag="KSE_RS23260"
                     /old_locus_tag="KSE_47160"
     CDS             18288..19193
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47160"
                     /product="hypothetical protein"
                     /protein_id="WP_014137795.1"
                     /transl_table=11
                     /translation="MRVSKKLRSVVTALAVVVGAFAAAAGPGAPASHAATRDGGTNWTA
                     LVGIEIVKKTGQINQFSQQTVYCPSGKVAIGGGGEASTGYPARRGHELSLVGSFPMGSG
                     TQAFGWASNARWDWASQTPLTVTTYAICAYMPTGYEVVGGAPTQVPSGQTIAMTCPAGK
                     VAIGGGGEVRGPNTGLSKSYPAAASGSAQMNQWVVGGFDMASSTTNTTAYAICSAPVPD
                     LTIARYNAASESPLGGLLKCPTGKIVSGGGASGSGPRASLVASRPAKAAETGSNDGWWV
                     QATDDLSTSDIDLYVMCVNR"
     gene            complement(19290..19658)
                     /locus_tag="KSE_RS23265"
                     /old_locus_tag="KSE_47170"
     CDS             complement(19290..19658)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS23265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_47170"
                     /product="hypothetical protein"
                     /protein_id="WP_014137796.1"
                     /transl_table=11
                     /translation="METGIPLLDTVLLWGGVVTVLATLGVGGWKCGRVVLRLAARAEEL
                     ADDCFGEPARPGVPPRPAPGALERVAAIEARVAAIEHEVHPSDGGSLRDVVDLANRRLA
                     QLCPAEADGDPPPAPLAS"
     tRNA            complement(19977..20061)
                     /anticodon=(pos:complement(5216516..5216518),aa:Leu,
                     seq:taa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="KSE_RS23270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="KSE_t0069"
                     /product="tRNA-Leu"
     gene            complement(19977..20061)
                     /locus_tag="KSE_RS23270"
                     /old_locus_tag="KSE_t0069"
     gene            20412..21185
                     /locus_tag="KSE_RS23275"
                     /old_locus_tag="KSE_47180"
     CDS             20412..21185
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137797.1"
                     /locus_tag="KSE_RS23275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_47180"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014137797.1"
                     /transl_table=11
                     /translation="MSSSTAYAAPTGLAAARATGLNKVYGEGETRVVALDDVSVSFGRG
                     EFTAIMGPSGSGKSTLMHCMAGLDDVSSGSATIGDTELVGLKDKQLTRLRRDKIGFIFQ
                     AFNLLPTLTALENITLPMDIAGTKVDRAWLDRVVETVGLSGRLSHRPAQLSGGQQQRVA
                     CARALASKPEIIFADEPTGNLDSRSGAEILSFLRNSVRELGQTVVMVTHDPVAASYADR
                     VVFLADGRIVDELHGPTADGVLDRMRRFDAKGRTS"
ORIGIN
        1 cgccagcagc gcggtgacct tgtacagggc ccgcaggtcc ggcgcaccct tgagcagctg
       61 acggcggatc tccaccgcac cctgcacacc ggccttcacc gacgcggcga cgtccgccgt
      121 gaggtccggc gcgggcagca ccaggcccgg ccggcaccac tgcgcggcca gcgacccgga
      181 gccgaggaga gcgaggacgt gcagcagacg cgacgtcacc atgccgctgc ggcactcgcc
      241 ttcggtgagc acggtcagac cgagcttcac cccgccgagg tcggcctcca actgctccag
      301 cacccgccgc aactcggcgg tgcccgccgg gtcggcgatc acgaacacgt cgaggtcgga
      361 ccagccgcgc tggtacttgc cacgggcgcc gctgccggtg acggccagca ggtcgatcac
      421 cgggggctgc tgcacggtgg tgcggtccag cagcgccgac aggtacgcct ccaggttcac
      481 cggcaggccg agggtgttga ccggcgcgac ggtcggcgtc cgcagcggcc accgggagcc
      541 gagggcgacc atgtcgagct gccgctccag ccgcagccgg gagccgttgt tgtcgaccac
      601 caggtgcgcg aggccggcga tccggtcggc cccgcgcgac accttcacct cgtcccggtc
      661 aaccacgtcg agcgggccgg ccgtaccgcg ccgcgcccgg acctccggct ccgcgtcaag
      721 gtagacgatc gagagctggt cgcccagcat ccggcgcagc tccgccgtgc tgtcgtactc
      781 gtgcagcgac tcgacggtga cccggtccag gaagtggtgc gccgcgcagt accggtcgag
      841 ggcatcgacc agcagctccg cccgcaccac cgggtggagc cggtacgggt cggcgacccc
      901 ggcccaccgg gcggcctcct ccaacaggta accgatcttg agtcgggcgt gcccgtgctg
      961 caccctcagg tactccccgg cgctgctctt gccgcactcg gacagcccgc cgagggcgac
     1021 gatccggacg ccgggcagcg cccgcgccgg aacggtcggc accaccgggt ggacgagctg
     1081 gcgcagctcg tcctggacct cgacgaccgg ccgcccgttg accacgatga cgttcgacca
     1141 ccggccgtcg gcggccaggc ggtgaagctg ggtgtgcagg tgccgctggt acgccgcgta
     1201 ccccggcgtc accgacttct cgtgcgacag cgcccgggcc gtgccgacct ccgggtcctc
     1261 gtggtggagg agcagcacgc cgaactcggc ggcctccgcc ccggcgaggt ccgcgcggaa
     1321 cggctccagc agcttgagcg cccggcccgc cgccgcgtcg gcgctcaggc cctcccggac
     1381 ggcgacggtc gcggcgaggg tcgcctccag catcgggatg ccccggtcga cgaggcgcac
     1441 ctgggcgtcg ccgagccggc ggacgcgctc caggtaggag ctggccagga cgtcggcgac
     1501 ctcctccacc ggcccgtgct cccaccacca gccgcccatg ccgcctgggc ccgcaacgat
     1561 ggccggccac cgcgggtcgt gggcgtctag cgtcccgccg gacgttccgg ccgggccgag
     1621 acgccgcagc agtatcccga gctgcttcgt cttccccgag ttgtccggcc cactgagcgc
     1681 gaccgtggca gaagtgagcg agtgagagag ggacacagtg tcctccgaga gctcgtctag
     1741 gtccgagatg gttggggccc cggcctgagt cgttagcccc gccagggagg atgaggttca
     1801 gaaggtcttg agggcgcagg gtctgggggc ggcggagatc agctgggccg gctcgggccg
     1861 cgccagacga tgacgccggc accgtcgtgg cgcgcgccgg ggtgctccca cgcggtccgg
     1921 aactggtagc ggccgatcgc ggcgaggtcg ccgaggagct ggccgacgcc ggcccgccag
     1981 tgctcggcgg cggccggggg cagcggctcc ccgtaggccc gcgcgaactc cggatccggc
     2041 caccacgtga cgtgggccga catgtgcgcg ccgggcggcc acagcggact gtcggtgtcc
     2101 agcaccgacc ggcgcccgat gtccgctacc ccggcaccgc ggcgcctctc ggcgaccgcc
     2161 cgcaacgccc cggcgacctc atcaccgggg gcggggcctt cggcccactg gggccacccg
     2221 tcgatgaagt tcggccgggt cggcggcacc ccgtcccagg ctccggccgg cggccagtcg
     2281 gcgacggcac cgggcggcag ctcccaagcc aggaaggcgc gggagccgaa gcgctccgaa
     2341 ccgcggtgcg ggccggtgac cgcagcctgg agacccaggc tcctcagtgc cgcgagcacc
     2401 gcggcggtgc tctcctccca gtgcccggcc gcgcccttcg gcacttcctt gcggctgtcg
     2461 cgggagaact ctgccgcggg gtgccagacg acgcgccagc acgcgagcgc accgggcggc
     2521 cacgtctccg gcggcgccca gatcaccatg caccaacccg gcgtcccgag caccggccgg
     2581 aagtgccggc cgtcctcggt gtactcgggc cgcttcctgt cgtagccgag ccttcccagc
     2641 tccgtctcca gccagtggcg ggcctcccgg gggcccagcc cgacggcgct caccggcccg
     2701 cccccggccg ccgcccgcgc ggagcccgca tctgggcgtg ccggtgccga ccgggcgggc
     2761 cgccgccgcg ccggatcccg ccgtacggca cgccgggcag gcggtcctcc tcgaggcgag
     2821 ggtgcaccca ccgcaaggtc gacagcaccc ggcagtacac cccgaagagg acgacgcccg
     2881 cgaacagatc cgacggcggg ttgcccagca ggcggcggcc gccgtgaagc gccgcttcga
     2941 ccgagccccg caccgccgag agctccggca gggcaccgta ggcggcgtcc acctccgcga
     3001 ccagcagggc aaggtgcccg accagctcgt ccagcagctc caccatcccg tcctcgggcg
     3061 gcggcccgcc gacctgggcg ccgaccgtga gcaggtccac gcggtccagc gctgcggcga
     3121 cggccgccgc gtcgagccgg accggctcat caggagtggg gtgcactgcg tcctccaggg
     3181 gagcgagggt ggaactcccc ggcctggccg cgccaggccg gggagcacgt gaaggctgcg
     3241 ggccgtccgc cggtggcccg cagccggtca ggcgggcagc tcggagacgg gcacgccgtg
     3301 gtgcagcagc gggaggagct ggcgcgcctt ccgggcggcc agcaccgccc tgacgcgggc
     3361 ggcggtcgcc gggaggagag caccgtcgaa ctcgtcctcg cgcagccaca cgtggccggc
     3421 gatctccccg gcggcggcct ccggcacggc cagcgcggcc agctcctcgt ccgtgatcac
     3481 cccgccgtcg aagaccaggt tcaggccctc gttcgagccg gtctccccgt tctccggggt
     3541 ctggtcgacc gcgaagaagt gcgagaggcg acggacgagg cccgtctcct cccgcagctc
     3601 ccgggcggcc gcccggtcga agcgctcgtc cttgccggcg gcaccgcccg gcaggatcgg
     3661 ccgctgcttg tacgtcgtga cggagaacag gacgcggtcc tcctggtcga ggatcagcgt
     3721 caggcagccg acccggcgcc tcggctgccc gtcgtgcggg atctcggcgt gtgtcatgag
     3781 gtacccccca gtagatgaag cgagttggat gcggtcgccc cgtcgaatcc gcagcgacgg
     3841 ggcgaccagc gggccccgcc cgtgcagcgg ggcccgctca accgccgacc gcagccggcg
     3901 gcacccgggg cagtgccgcc ccgggagact cgttggaccg ctacgcgacc cggggccgcc
     3961 tgaccgcgca gaggcgggac acctggagcc ccgcggtgac ggcggctcgg cgcagcactg
     4021 cctcgggcac gccctggacc gcgcgcctcg ggtgcggggg ctggacgggc acggccagcc
     4081 gcagctgcgc ccagaccttc ttgccgcccg aggtcggcac ccagccccag ccctcggcca
     4141 ggtcggcgac gatgagcagc cccctgccgt tctcccgcac cccgtcctcg cgggcaccgg
     4201 ccgggacgta cggcaccgcg cggctcaggt cgtgcacctc catcaccagg gcggtgccgt
     4261 ccggggccag atggagagcg acgtggtgca tgccgggcgg actgtgccgc gccgcgttgg
     4321 cgaccaactc cgacagcatc tgcaacgcat ccaggacgtc gcccttggcc agcccccact
     4381 cctccagcag caccgtccgc gccctgtgcc gcacgacggg gacggcgtgc agacggctct
     4441 ccagctccgc cgcggtggcc tcgaccgtca tccgcgcggt gagctcggga ttcgcccgcc
     4501 ccgggtcggc cttcaccgct gcgccccggc gtcgaccagc tccaccgcgg ggggagcggc
     4561 gggggcgggc gggagctgct gcgccccgtc cgtgggcggg aaggacggtc cgggcgtccg
     4621 atgggtgacc agaacagccc cgtgctgggc gacggaggcc gcgagccggt cccagtcctt
     4681 gcggccgacg gcgagcatcg tgcggtcgag ggtcacgacc atcacgacgt gaccaccggc
     4741 cacgagcgcc atcacgtgct gccagccggg gcgttcggcc ggcgggagca ggccgtcggt
     4801 gtcgaggacg gtctcggtca ccgggatgcc ctcggcggcg gcgcgctgct cgcaccaccc
     4861 cgccatgagg ggacggctga ccttgtcgtc ggtgcagagg tacacaaggg cgctgcgcat
     4921 cgggtagctc ctgtggacgg ttggagccgc gcccagcacg tcggggggcg tgccgggcgc
     4981 gacgtcgacc cggactcttc cgtgatccgc tcgcgcggct cgccgggtcg gctgcatcca
     5041 gtcaaacggg ggggcgaccg ccaggggcag ggtggtttcg gatccgactg cgcgcaagca
     5101 cccggaagtt ttgactttcc ctttactcga agcccggcgc ggatcgtcac cctgtcgcta
     5161 ctctcggtgc gtgggggata acctggaaat tcagcgacgc atgctcgaac tgggcttcag
     5221 tcaagtcgag ttggcccacc gggtgaacga cgtgatcaag acgctcaccg gccgttacgg
     5281 cacctgctcc gagcgcaccg tgcgggactg ggtgagaggc aaagtcacct ggccacgcgg
     5341 actccagcgc cgctcacttg aggaagtatt cgactgcacg gccgaggaac tcggcttcca
     5401 gccacgggga gccacccccg cacccccacc gacggagaac gacgtgaggc gtcagacctt
     5461 cctcaagggg atcgctgcca ccgccaccac agcagccggt ctcaccccat cccccgccac
     5521 cgcagcgccc cggacaacca tcggcacatc cgacgtgatc cgcctgcgcg cgggcctcga
     5581 aaccctcgac gccctggacg accaccgagg cggacacggc gcgctggaga aagccgccct
     5641 cgctggtgca gccgaggtga tggcactcca acgaactggt agcgccagcg aacggatccg
     5701 cagccggctg ttcagtgtcg ccgccgacta caccgccgtc gccgcctggt cctgtatcga
     5761 tgcccgagac ctcgaccaag cccaaaagca cctcgacacc tgcatgcgac tggccggcct
     5821 cgcccgagac cccgtggccg tcttccgtac ctggaacatg atcgcgatgc tggccaacca
     5881 gctagggaac taccccgacg ccgtcgcagc cgcccgcgcc gcacagcgaa ccgggatcac
     5941 ccgccgcgac cccgccttcg cctcgctcgc ccacgcccga acagccatcg gcagcgccgg
     6001 cctgaacgac cgccagagcg ccctccgctc catcggcctg gcagcggact ccctcggccg
     6061 cgcacgcggc gaccagccct gcccgagctg gttcgcgttc tacggcgctg ccgaactcca
     6121 ggccctcacc tcgatcgtcc aggaccggct cggcgacgca gtcagcgccg aaagcgccag
     6181 ccaccaggcc ctcgcactgc tgcccgccca gttccgccgc aaccgagcac tcgccaccgc
     6241 ccgcctcgcc ctgacacaac tccaccagga tgaggtggac ctcgccgtcc acaccgcgtc
     6301 ctcggtcttc gacgtcatgg ccggcgaccc cctgccaggg cggatgcgca ccctcctcgg
     6361 agacttccac cgcgagctgt tgaccctttc cacgaacgcc ccggctgcgc aagagtgggg
     6421 ggatcgctac cgcgccgaat ggagccgaac gtgaccgacg cgacccacct gcgtcactac
     6481 cgtgccgacg acgtgaacga cccgttccgc cagatgctga tcgccatcca cgcggaggtc
     6541 tacgccgacg tgatggatga cgagttcaac cagcgctttc cgtggttcgt caaccactgg
     6601 agcagcatgg agggcttctc ctgtgtggtg gcgtacgacg gccaagagcc catcggtttc
     6661 atctacgggg cgcccctctc ggccggccgc gagtggtggc gcgagcacat cgtccccgcg
     6721 ccggaggact ccagcacgtt cgcggtgtcc gagctgatgg tccgcccggc ctggcagaag
     6781 caggggcact ccacccgcct ccacgatgag ctggtcgcgg accggccgga ggccctggca
     6841 gtgctcctcg tcgataccga acaccccaag gtccaggcac tctacgagag ctggggatac
     6901 gcgaaggtgg gcgaccgccg ccccttcgcg gactccccgc tctacgccgt gatggtgcgg
     6961 gaactgagct gacatggccc tccggagcat ggccgtcgcc cactacaccg ccgaggatct
     7021 gcccgagatc gagccggtgc tgctcgacct ctacgaccgg atctacgccg aggagaaggc
     7081 gggtgacccg ttcttctcga tggaggcgtt caccggccgt ctccaccgcc aggccgccgc
     7141 tccccgctgg ggctgtgcgc tcggggaggt cgacggccgg ccggtcggct acgcctacgg
     7201 gttcgcccgc accgccgact accggtgggg cggcttgatc gagacggagc ccggcgccga
     7261 cctcgcggag acggacagcc gcacgttcgc gttctgcgag atcatggtgc tcccggagtc
     7321 cagggggacc ggcatcgccc acaccctgca cgaggagctg ctgtcgcacc gtcccgagga
     7381 gcgggtgcac ctcctggtcg aggaggacca cccgcgggtg cgggccctct acgagcggtg
     7441 gggctacacg aagatgggga tcatccagca ccccgggtcg ccacgctacg tctccatgct
     7501 ccggcccgtc gccctctgag ccggcggggt cgacggcacc cgggcgcact cggcaaaggc
     7561 cgtgacgacc gggcggcgat cctgttcgga aggtcaagtc ggagcgctgc ccgccccggt
     7621 ggttccactg cggctaccac ggcgtgatgg ctccggccgc ggaccgcaag atccgggtct
     7681 tcgccgaccg gacccttcgt gccgggggag gggtcggtca tggctccagg gtcggcgatg
     7741 aacgctgcct ggtgaaggat tcgttgtgaa cgagttgttc aatggctggg tcgcgaagcg
     7801 gtacccgaag tcggtgagcg gggcatcacc gcaggtgacg gtgggtgggc atgctggtgc
     7861 ccagagccgg actcgaaccg cagggagtgc ccccgctgac ctgcgacgat ctgccggcct
     7921 gcgaaaacga gcccgcatct ccccgttcca gcccggatct ccccggatat aaccgccccc
     7981 gtgctcccgt gggagcacgc ttgggagcat gggcaggtca cgcagggtga gggggggtct
     8041 gggggtgggt gcctggggct tggagcgatc cggccactgt tccgagaagt tggccgaagt
     8101 ccgccccctg tcggcgcagg ccgggaagga cctcccgggg ggaaacggga agagggcccg
     8161 gcagcgtact gccgagccct cctatccacc ccacatccag cttgcggagc atggacacgg
     8221 gcggtctgtg ttgcccgctg acactatgcc cgatcggatt gccgtccgga gcaaacatca
     8281 cccgaaagag atcggccgcg gcgggaagcc gccagcctga cggcacgtca acttccgttc
     8341 ccccagcgga gaagccaaag ccgggcaagg gaacggcccc ggcgaagact gccggggccg
     8401 tgacggagta cgtgctcggt cagtaggaga tggccacccg gcagcccggc ttgtcgatga
     8461 tgtacccgtt gccgatcttg gagtccggcg tcccggccgg gtacagcttg atggtggggc
     8521 gggcctcgcg atccccgtcc caggcccgga tctgcttgca caggcggtcg gcgagatcct
     8581 ggccggccgg gccgcggccg gtggcgccga gttcgaagcg gacggggccc tcgccctcgc
     8641 ggcgggtcaa gatgaggtag gccagggagt cgccctcggc cagggcgggg ctgcggctcg
     8701 ggatcgccgg cttgcacagg ccaccgtcgg cggcggcccg gtcggcagcg atccggcacg
     8761 tggcgggggc ggtggtgctc atcagggtgg tgtccttccg tggcagggtg gttcgcggtc
     8821 agcccgccag caggcgtccc agcgaggggc gggcgggtcg gtcactcggc gatgtgccac
     8881 cggccgggca ccagcagcgg gtcagaggag ggaccggcca gctgcatgct gcaggaccag
     8941 gcgatgaggg gcggccgccc gctcacgtcc caggccgccg cacggtccgc ggtggtccgg
     9001 acgagcgcgg cggtctcggc gtcgctcccg gccgagtaga ggccgtccgg ctggacgaac
     9061 accccggccg tctcgtcctc ggtgacgacg gcgcacccgc cgtacgtgcc gtcctcggag
     9121 gcggcgcagg tgacccgggg gtcgtgcccg gccaggaaca tgcacaggtc ggcgaaggcg
     9181 tcccggtcca ggccgccggg gaacggcccg gcgacccggc cggcgggcac cggcaggtac
     9241 gagccccggg aggacggcgg cacgggtcgg ccgccgtaca aggggccggc ggcggtcatg
     9301 aagtcggcca tcgtgaccag gcgcccggtc ggggtgccgc ccggcccggg ggcgtagacc
     9361 cgcgtcagcg ggtgcacgcc cccgtgcgcg agcggtgcga ggatcatgcc gttcggggtg
     9421 agctggtcga gccacgccgg ggggatgccc gcgatgccgc acgtgacgat gatccggtcg
     9481 aagtagccgt tgctggggta cccgagatag ccgtccccgg tgtggacgcg gacccccggg
     9541 acggccgccc gctccagcgc ggcgcgggcc tcggtggcga ccggttccga gtgctcgacg
     9601 gcggtcaccg ggccgccggt gatgtgcgcg atcagcgcgc tgttccagcc cgttcccgcg
     9661 ccgatctcca gcacgtccat cccggggtgc aggtcggcgg cctccagcat cttcgccacg
     9721 atcgacggct gcgacgtcga ggaggaggtg cccgaggtgt cgtcgggcac gtgggtggtc
     9781 aggccgcggt cggagtagac gatcgccagg gtctccgggg tgggctgctc ggggtcgacg
     9841 gcggtgaagc cgccgggccc gtagtggccg gagacgaaca ggtgccgggg gacttctcga
     9901 agggcgcggg cgacggcatc ggtgcggacg gcgcccttgc cgcgcagatc ctgcacgaga
     9961 gcgtcggcgg cctgctgcca ggcggtcggg gcggtggtgg tcacagggcg gctccttgcc
    10021 ggtagacggt gacgggaagg taggcggggc gcgggtcgaa cggctcggcg gcgggctcgc
    10081 ctgcggcttc gatccaggcg tggacgtcgg cggtgcccgg ccgcaggccg atcaccagcg
    10141 tgggggcgtg cccgtggaaa cggcagtaca ggacggcggc caccgacctg ggcaggcacg
    10201 ccgttgtgcc accgagccac aggaaggccg tggtgacggc ctgcacggcg tgctcggcct
    10261 gctcgggggt ggacggcggc agccggccgc gcagcgcccg gttcaggacg gtgtgcagcc
    10321 gcccgtcggg gcggccgccc cgggtggtcc agacggcggc gagcccggag gcgagagcga
    10381 ccaggcgctc gccggggcgc agccggacgc gggacggaag ggcagtgacc acgctcaccg
    10441 atccgtcacc accccgtgcc ggcgcagggc gtccaggacg tcggcgacgt cacggcggac
    10501 agcagcggct ccctgctcgg ggaaacgtgc gagcagagcg acggccgcgg cctcggcgcc
    10561 gcctccccgc tccatggcct ggagcacggt gacggcggtg gcgttgagcg tccacacgtc
    10621 gccggcggcg gtgacgaggg tgccccggcc ggtgtccgcc gcggtgagca gccgggcgcc
    10681 gggggagagg gtcagcacag cacggctcct tcggtcagcg ggcggccctc ggcggtgcgc
    10741 gcccacacct cggcgttcag ggtcatcagc agcgtcagct cgtccgtgcc ctcggccgcc
    10801 gcccattccc ggaccgccgg agcgagggcg gcggggtcga ccaggccgtg gtcggcgagc
    10861 gcgctgtcgc gcagcagcag cgaggccagg ccgcggcggt gccgtcgggc ggcggcgcgg
    10921 tcatcggcgt tgtagccgcc tttcgtccgc cgggtgagga cttcggcggg caggacgtcg
    10981 cgcagcgccc ccgtcagcag gggcttgaac gcgaacggcg aggagcggtg gtggccgcgt
    11041 acggacaggg cggcatccag gaccgcccgg tcctggaacg ggtaggccat ccgcaggccc
    11101 aaggtgcctg cggcatccgc ctgcagccgg ttccagcggg ccatcgcccg cagcgccgcg
    11161 accgcggtgt gctggtgcgg ccggtcgtgc agcggcctcg ctccggctgc ggcgtcccgc
    11221 agcctctcct ccagccgccg gcgcgcggtg acggtcagcc acctcggcac ccacgggccg
    11281 gactcccagt ccatcgcgcc gtcgagcgcc ccggcgacgg ccgcgcggta cggcccggga
    11341 aacgcggctt cggcccggac gtcgcgcacc cgggtgccgc gcagtgccgt ccacccccgc
    11401 cggtgctggc gcgccagcag ccgcggagcc gagccgaggt acgtcagggg cggcagcagc
    11461 acctcgtcgc cgcccttccc cgacagcaag acccgggccc cgccatcgag cgcctgctgc
    11521 cacaggaacg ccgcccgggc cgggctcacc gcggtgggcc ccggggagtc cagcgggagc
    11581 gcctgctgcc agccgtcgaa ctgcccgggc acctcgccga ccgccaggac acggtgcccg
    11641 gcaccgggct gagcggccgt caccagccga gcccaccgca ggtcgtcgtt ggccgggtcg
    11701 gcggacgccc tcgacaggtt cagggtgcgc ggtccgaccc gctcgaaggc gagcgccgag
    11761 agggcggagc tgtccaggcc gccggacagc tcgaccgcga ccggggcgtc ggcctcgcac
    11821 cggacggcga ctgctccgcg cagcgcctcg cggagcagca ccgccccgtc ggcggcgcca
    11881 acgtcgtcgt cgggcaccgt ccaccacgct tcggtgcgca gtgccccgga cgcgtcgatg
    11941 cgcgccgcag tgcccggcgg caactcggac acgccccggt aggggctggt gccggactcc
    12001 gcgagggcca gcggcggggc gggcgcgagg agctgcaccg ccaagtggtc gacgtccaga
    12061 tgccggtggc cgagcgcggc cagcggccgg gcacgggaac cgaggaacac cgcgccggac
    12121 tgcacggtgg cgaacaccgg gcgcagtccc gcagagtcgc cgaacagcca cgtcaccgag
    12181 ccgtccagca ccaccaggtg gtagctgccg ggcagctcca gtagccgctc ccagcggccc
    12241 gaaggccgca gcgcccctgc acggtcggcg agttcggcgg cctccacccg gtgatcgccg
    12301 atcacggcga cccggtaccg gccggcgctc gtgctggtga cccggtcgct tccggcgcgc
    12361 ccgacgatcc atggctgatc atcggcccag gccagcactt cggcgccggc ttggacgaga
    12421 gcagcagcag gccgtgctgc cgggggcttc cccggcagca cggtgaacca ctgtccgaac
    12481 actcagccct gctgctggta cttggtggtg tagtagtcgc cgtcgtcgga gatgcccgac
    12541 gagtacgagc cggcggccaa ggagccgacc gtcccggcca gcgtcgcggt cggcgcctcg
    12601 tactcctcgt gcccgtcggt ttcctcgacg ctctgcttcg tctccatcag gatctcctgt
    12661 cttctcggcg cggcagcagc cgcgctgtgt tcaatacccg taccgggtac cgatgttgtt
    12721 ccggccgccc atcgtggtgg acggccgtgt gccgccgggc ggacagcccg gcggagcaga
    12781 tggccgccgc cccgacggcg caggcaccgg ggcggcggag gggatggccg tccggatcac
    12841 gcggcaggcg gcggggatgc ctcggcccgg tgccgggcca gccacagcgc ggggctgtcg
    12901 agttcggcgg acgtcggcac ggtgtcctcg ccgtcgaaga tgctgctcag catcgccggg
    12961 ccgccggcgt cgtgcagggc cgacatgaac tgctggccgc gcaggtacag cgaccgatcc
    13021 gggacgatcg gcaggaactc ggccaccctg cgcagggcgc gaaatcgcag cttcgccttc
    13081 gggtcaccgg ggaagtggtc ctcgacaccg ccgagttcgg cgaccaggcg gcggtgcacc
    13141 cacatcgcgt gtccctcgct gacctccggc accggcagga cgtcccgcgc cggccgccgg
    13201 ccgatccggg cctcgaccat ctgccggacc cacatcggga cgagacccgg gaaccgcagg
    13261 aactcggcag cgtggacgag ttcgtgcccg agagtctggg tcaaagcccg ctgcgaggtg
    13321 cggttccccg cgtgcatccg gtgcacgacc agcagttccg ggccgacggg cccgagcacc
    13381 atctgcccgc cgatcagcgg ccagcacagc cgagtcatca ggccggtgat cgcgccctgg
    13441 gtggccgcca gcttcagcgc ggcggcccgg tgctcctcgg cctcgaactc ggccgagacc
    13501 atccggccga cgatcgtgaa gtgccccctc gtgatgcccg gcaccgcgcc ggggcgcacc
    13561 aggcgcacgg tcacctcgtc cggcagcggc agcgccgaca gctccacgat ccggggagca
    13621 gccgcgtaca gcgcctcctc ggcccggacg gtgaacgccc gaccggccga ccccgcctcg
    13681 ttgctgatca gaaagctcgt catcctcggt cctgtctcgg ggctctggca accgctcagc
    13741 tgtggtggcc tcccccaccc gacccatggg agggggaggc ccggcgcgcc cgacagcacg
    13801 ccgttgtccg ccgatggacg cggcggcccc cgggggagca accccgggag ttcgtggtgc
    13861 ctacacggcc gcccggcgag gccagaccgc gcacaggcgg gacgtacggg ccaccgcggc
    13921 gcgatagatc tcgggctgct tgctcacgcg ggcctcccgg ctcgacagtg cggctcgtgg
    13981 atgatcgctg cgatgctgcc gccacctgtc caggtgcggg cggtgatgca ggagcccgcc
    14041 gccctggcga ggcccagcac ggcccagcag tccgccaacg aatcagggtt ggcgggcgcg
    14101 gccacgcgat agcacccgca gcccacacgc tgtatcgccg cctcggcgcc ggtggaggcg
    14161 gcgtagcgcg cggcggcgtc gaacaccgcg gtgctcacgc ggaccgctga gtggtggcgg
    14221 cggtgaggta gtcgtcccag cagtccgaga cagccgggtt ctggtcgcgg ccgacgccgg
    14281 tccggcagcg ggcacaggcc ccgcacggcc ggtaccgggc atcctgctgc gggcgctggg
    14341 acgggctact ggccatggcc ggcctccagg tcccgggtgc acaccaccgt gtcgtagtcg
    14401 cgcaccaccc cggcacccgc ctgcagcgtg acgacgccat ccgggtggag gggcctgcgg
    14461 gtggtgcggc acacgatgca cgcccggccc gcgagctgct cgtcgctcgc gaggatgtcc
    14521 acctcgcggc cgccggccac cgcccgggtg acccaccggg cggtggcgag gtggcggagc
    14581 acggcggcca ggcgcagcgg gtcgacgagc tggtccaggt cggtcggtga gggcggggcg
    14641 atccagcaga ggccggtcgg gtcgaccctg tcgacgccgg ggactccgat gtaggtgccg
    14701 cggctgagcg ggcgggtgcc gagggcgggg tccgccgctg cggcggccga ggcggccggg
    14761 acgaggaagt agagggtgct gttgcgggtg tcccagatga cgggaccggt gcggtggcca
    14821 gtctcctggt cgaggaccga cagggcggcg aggccgggtt cctgctggac ggcgacggcg
    14881 tcccagtgga ttccggcctc ggtcacggcg accgtgccca ggggcggtgc ccaccgtggt
    14941 gtgtcgagag gtaacgtcat cgcccgctcc tgtctcctgc tgatccgtca tgaccaatgt
    15001 cggacacagg tggcgggcgg actcacacag ttctgtgtga gtccgtcaga tgccggccca
    15061 ctgggcgaac tggacgacct gctcgggcgg gcggcggtgc gcccggacga tgccggtcgc
    15121 ggcgtccttc accttggcgg agtgccggat ctgctgcggg gcgagttgcc gggcggtctg
    15181 caggcgggcg aacgcctcct cgggccggcc gagccacagg tgcgcgcggg ccatctcggc
    15241 gtggtggtgc gccgcccggg acgtcgccca ggtcgcgggg atctctatcc gccgggcaac
    15301 ctccagcgcc tcccggtaca tgccctggtc gacgtagcaa ctggccctgt gcgcggcggc
    15361 gttggtcggg ccgaacgaca tccacaaggt ggtggtctcg ccggtcgcgg cggcgtaccg
    15421 gtcggcggcg gccaggtact cctcgacatc gtcgcgctgc ccggcgccgg cggacagcac
    15481 cgcgctggcg aggtagagct ggccggtgac cgcgcgccgg tcgaggcccg ggtcggcctg
    15541 ctcgacggtg gcgcgggcga gggccgcgat gcggatgccg gtgcgggcct gcccggacct
    15601 caggtagagc atcgcccggt tgtacatccg cagcccggcg acggccgcgt cggaggcccg
    15661 ctcggcggcc cagcccatgc ggtcgagcgc gatcgacgcg aggtcgggat agccggtctt
    15721 gctggccacg tcgtaggcgg tgcggtactg catcgccagg gcctgccaca ggcggcgggt
    15781 ctggtgggtg tgggcggcgg tggtggtctc cacgatcagg ccgggcagct cggcggcggc
    15841 ggcgcgcagg tcggaggcgc ggatcagcgc gcacaggcgg tcggtgtccg cggcgagcgc
    15901 ggcctggtca cggggggcga cgtccgggtc ggcgccgagg tcgtacaggt cgagggcctc
    15961 gcggatcggc tggacgagcg cggcgagctg gtcgcggcgc agctcgtcgg ttcggggctg
    16021 gccgagcagg tccggtacgc gcatgcccat ggcgcgggcg agggccgcga cgacgccgtc
    16081 gcccggggtg cgggcgccct gctcgatcgc gccgatgtac gacgtcgaca ccccggcgtc
    16141 ctgggcgagc tggctttgcg tcatgtgccg cattttgcgg gcctgctgga ggcgccggcc
    16201 gaaatcctgg tccacgtccc gacggtagcg ctgtcgagcg cgggcgcggg accgcttcgg
    16261 agagttgccg cccgccgggg ccgccgtgtt gcatgggccc atgccgaacc cgcgccccgt
    16321 tgtgtacctg ttcgcgtccg ccgcgccgcc cgcactggag ctgcccgacg tcgtccgccg
    16381 ggcccggggc cggggctggg acgtcgcggt ggggctgacc ccgaccgccc gggactggct
    16441 ggacgagcgg gtgcccgagc tggaggagct gaccgggcac ccggtgaaga ccgcgtaccg
    16501 gcgtccgggg cagccggacg tgctgccgcc ggcggacgcg gtgctgttcg ccccggcgac
    16561 gttcaactcc gtcaacagct tggcggcggg gatcacctcg tcgtgggtgg tggggttcgc
    16621 ggcggaggcg cccggcaagc ggattccggt ggtggtgatg ccgtgcatca actccgcgct
    16681 ggtgcagcac ccgcagttcg accggagcgt ggcggtgctg cgggaggccg ggatgcgggt
    16741 gctgtacggc cccccggatg ggttcgtgcc gaaccggccg ggtgagcgcc tgccgtaccc
    16801 atgggagcgc gccctcgcgg cggtggagca ggcggtgtag cgggctgaat cggtcttcgg
    16861 aaagccgccc ggttaagccg agcggggcgg acttgcgcca ggcggatgct ggtcaggcca
    16921 gcacgaagga gtccgggggc ggcggcatca tcgccagcat ccgggccatc tcgccgaagg
    16981 cgctggcgat cggcacccgc acccacagct ccgcgcacac ccggcaggag atccgcagcc
    17041 cgtcgccccg gctgcacacc cggtgcccgt cctcgacggc gtgttccggc accgggtgcg
    17101 tacacaccgg gcacggccgc agccgggcca cacgctcgat ctggcggcgg gcccgggccg
    17161 cccgcgggta cgggcggcgg ttcggccgcg tgtaggggcg cagattcacc gcccaccccc
    17221 gacatggcgg tgccccgccg atgggggggg agatcggcag ggcaccgcag ttccccgccg
    17281 ctcggggggc gttcggcggg agcaaggccg agtctgcccc cgaagcgtga tcgctatggg
    17341 cgatttgccg atgttcctcc agaacggcca gtacgcgcgc cgtccgctcc tcctcgcgcc
    17401 ggtccgcact cgcagtgagg gcgcggtcga ggtccaccgg gccgcaggcc gccagtgcct
    17461 cgaacaccga ccggccctcc agctccagct cgggggccgg gatcacgatc accgccggtt
    17521 ccagcccggg ccactcctcg tggcaccagc cgcacccctc ggagcacggc cggcgcaggc
    17581 accccaccgg cggaccgccg ggccggcgcg gaacctccgg gagcggcagc ccgggcgccg
    17641 tcactccccg ctcccggccg tctcggtcga gccgtccgcc ggctgctccc cggcggcctg
    17701 gtcgatgagc ccggctgccc tcaccgcgcc gagggccggg tgcagcttct cggccatcgc
    17761 ctggagatgc cggaccgcct cgtccaggac gtcctgctcg gggccgcccc accggcccgt
    17821 cgccagctcg accaactcca cgtcgctgat gttccgcagc cacatcgcgc gctgctccgg
    17881 ctcccgcttc gccagctcga actgccggac cacgccggcc aggcggtcca gcccaccgtc
    17941 cgtcaggtcg agccggaccc tcccgtcgtg ggtgaagacc acgccctgga agtcctcggt
    18001 gcccaggtgc agcgacgtca tgttcagcct ccgtgctcgg ttgggccgga caggatggca
    18061 caaaccgcgc cgggccggtc ggccgcgcgc cgtcaccacg agtgccgctg ttcgaccgaa
    18121 accgatcacc gttcgaccgt gacagcggac aggcgtcgaa tccgttgggt atcacgggtc
    18181 tccgccccga aaggcggacg tggcgatgtc gaacaaccag ggaggcactt tgggctatgg
    18241 aatgatcacc gcccgtaatg atcgcgtgct cattcagggg agttcccatg cgcgtttcga
    18301 agaagctcag gtccgttgtc accgcattgg ccgtcgtggt cggggcgttc gcggcggcag
    18361 ccggcccggg ggcgccggcc tcgcacgccg cgacgaggga cggcggaacg aactggaccg
    18421 ccctcgtcgg gatcgagatc gtcaagaaga ccgggcagat caaccagttc agccagcaga
    18481 ccgtctactg ccccagcggc aaggtcgcca tcggcggcgg cggggaggca agcacgggct
    18541 accccgccag gcgcggccat gagttgagcc tcgtcggcag cttcccgatg gggagcggaa
    18601 cccaagcatt cgggtgggcc tccaacgccc gctgggactg ggcctcccag actcccctga
    18661 cggtcacgac ctacgccatc tgcgcctaca tgcccaccgg atacgaggtg gtcggcggcg
    18721 cccccaccca ggtgccctcc gggcagacca tcgcgatgac ctgccccgcc ggcaaggtcg
    18781 ccatcggagg gggcggcgag gtccgtggcc ccaacaccgg cctgagcaag tcctacccgg
    18841 ccgccgccag cggctccgcg cagatgaacc agtgggtcgt gggcggcttc gacatggcga
    18901 gcagcacgac gaacaccacg gcctacgcga tctgctccgc acccgtcccc gacctgacga
    18961 tcgcccgcta caacgcggcc tccgagagcc ccctcggcgg cctcctcaag tgccccaccg
    19021 gcaagatcgt ctccggtggc ggcgcctccg gcagcggacc gcgggccagc ctggtcgcca
    19081 gccgccccgc caaggccgcc gagaccggct cgaacgacgg ctggtgggtc caggcgacgg
    19141 acgacctgag cacctccgac atcgacctct acgtcatgtg cgtgaaccga tagcagccct
    19201 gcaacgcccg ccctgggccg gcctccgctg ccggcatggt gccgaccatg aaccgcccgc
    19261 ccctggagct gtgggggcgg gcggtccgtt caggacgcca gcggtgccgg cggtgggtcg
    19321 ccgtcggcct cggccgggca gagctgggcc agccgacggt tcgccaggtc cacgacgtcg
    19381 cgcagcgatc cgccgtcgct ggggtggacc tcgtgctcga tggccgcgac ccgggcctcg
    19441 atcgccgcga cccgctccag cgcgccgggg gcggggcggg gcgggacgcc cggccgggcc
    19501 ggctcgccga agcagtcgtc cgccagctcc tccgcccgcg cggccagccg cagcaccacg
    19561 cggccgcact tccacccgcc gacgccgagg gtggcgagga cggtcaccac gccgccccac
    19621 agcagcacgg tgtccagcag cgggataccg gtctccacgg tcgctcctcg ctgcgtgggg
    19681 tgcgccgggc cttgcctttg gtccggcccg gtggacagca ctggcctgcc tcgtccggcg
    19741 agtcctcgga gacgatggcc gagtccgtgt tgtcgaaccg ctcgcgccgc tggctccgcc
    19801 ggtcttttcc ccgtcgtact ccacctggat cgaggcggtc tcgtcggcgg cactctcacg
    19861 ttccgcgacg cacgccgtcc cgaggtaagg actcgcgtgc tcccaaggcg cttccgcacg
    19921 cgaagtgcga gggccgtgat tgggtcatca ccgcaggtga cggtgggtgg gcatgctggt
    19981 gcccagagcc ggactcgaac cggcacggcc tcgcggccaa gcagttttaa gctgcccgtg
    20041 tctgcgttcc accatctggg cctgggggct ggcgaactca ctcctgagcc tagtcggccg
    20101 ggcgagggtt tcgcatattt cctgggacgg aagttgtcat gcttccatgc catctgacga
    20161 agcgtccggg gtttcggcca cgctccggcg gttctcggcc atccggagtc ccggccggcc
    20221 ctcgggggag gggtcatccc ggaggaggag aaggcgcccg gggccgtaca cctggcggcg
    20281 gtggggcaac cgttcggcgg agcgacgtgg gcgggggagg gcggccgcga ggatggagta
    20341 gcggtcggag gagcgttccg agccggtcgc gccgtgacga aaccccaccc tcccggacag
    20401 gagtccccac cgtgagcagc tcgaccgcgt acgcagcccc caccggcctg gcggcggccc
    20461 gcgccaccgg cctgaacaag gtctacggcg agggcgagac ccgcgtcgtg gcgctggacg
    20521 acgtctcggt ctccttcggg cggggcgagt tcaccgccat catggggccg tccggctcgg
    20581 gcaagtccac gctgatgcac tgcatggccg ggctggacga cgtcagctcc gggtcggcca
    20641 ccatcggcga caccgagctg gtcgggctga aggacaagca gctgacccgg ctgcgccggg
    20701 acaagatcgg cttcatcttc caggccttca acctgctgcc gacgctgacc gcgctggaga
    20761 acatcacgct gccgatggac atcgccggca ccaaggtcga ccgggcctgg ctggaccggg
    20821 tggtggagac cgtcggcctg tccggtcggc tctcgcaccg gcccgcccag ctctccggcg
    20881 gccagcagca gcgcgtcgcc tgcgcccggg cgctggcgag caagccggag atcatcttcg
    20941 ccgacgagcc caccggcaac ctggactccc gctccggcgc ggagatcctc tccttcctgc
    21001 gcaactcggt gcgcgaactc ggccagaccg tggtgatggt gacccacgac ccggtggccg
    21061 cctcgtacgc ggaccgggtg gtgttcctgg ccgacggccg gatcgtcgac gagctgcacg
    21121 gcccgaccgc cgacggcgtc ctggaccgga tgcgtcgctt cgacgccaag ggccgcacca
    21181 gctgaccccg cgtcagccca gtcgaaccga ccgcatccac tccccgggac tgaccccatg
    21241 tatcgcaccg cactgcgcaa cgtgctggcc cacaagggcc gcctcctgat gacggtactg
    21301 gccgtgctgc tcggcaccgc cttcgtggcc ggcaccctgg tgttctcgga caccatgggc
    21361 caggccatgc gcaacagcta ctccaccagc tactcggacg tctcggtgct ggtctccgcc
    21421 gacggcccgg acgacggccc ggccgaccgg gacgcgcccc gccccgagaa gggcgcgctg
    21481 acccaggaga ccgtccagcg gctggccgcg ctgcccggca ccgagcgggc ccggggcgtg
    21541 gtctccggct tcaccggcgt cgccgacaag aacggcaacc tgatcggcga gtcctggagc
    21601 gcccgcggcg tcaacttcgt cccggacgcc tccggcgcgg acagccgcta cccgatggcg
    21661 gacggccgcg ggccgcgcac cgccggcgag gtcgcgctga accggcaggc cgccgacaag
    21721 gccggctacc gggtcggcga caccgtccgg gtggccggca acggcgccgc ccgggacgcg
    21781 gtgctgaccg gcgtcttcac caccgacgac ccgcaggtca cctccggcgg caccctggtg
    21841 ctgatggaca ccgccaccgc gcagcgcgaa ctgctggagc ccggccggtt cagctcggtg
    21901 gtgctgaccg ccaaggccgg caccggcgag caggcgctgc tggagcaggc ccgggccgcg
    21961 gcgcccgcgg acggcgtcga gctgaagagc ggccagcagc tcaaggacga ccaggtcaag
    22021 atggtcgacg actcggtctc caccaccaag accatgctgc tggtcttcgc cggcatctcg
    22081 ctgttcgtcg gcatcttcat catcgtcaac accttcacca tgctgatcgc ccagcgcctc
    22141 aaggagctgg cgctgctgcg ggcggtcggc gccagccgcg gccaggtcac caagtcggtg
    22201 ctggtcgagg cgctcgcgat cggcgtgatc gcctcggtcg gcggcctgct ggcgggcatc
    22261 ggcatcggcg cgggcctgca gtcgctgctg cacgccttca acgaggggat gccgaccggc
    22321 gcgctggtgg tcgccccgac cacggtcgtc gccaccctgg tgaccggcgt ggtggtcacc
    22381 gtgctgtcgg cgctgctgcc ggccgtccgg gcctcccgga tccccccggt cgcggcgatg
    22441 agcagcggcg agcagcccag cacccagcgc ggcctggtga tc
//
