LOCUS       NC_016109              23529 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Kitasatospora setae KM-6054, complete sequence.
ACCESSION   NC_016109
VERSION     NC_016109.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora setae KM-6054
  ORGANISM  Kitasatospora setae KM-6054
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1
  AUTHORS   Ichikawa,N., Oguchi,A., Ikeda,H., Ishikawa,J., Kitani,S.,
            Watanabe,Y., Nakamura,S., Katano,Y., Kishi,E., Sasagawa,M.,
            Ankai,A., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Nihira,T., Horinouchi,S., Ohnishi,Y., Hayakawa,M.,
            Kuzuyama,T., Arisawa,A., Nomoto,F., Miura,H., Takahashi,Y. and
            Fujita,N.
  TITLE     Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
            snapshot of the family Streptomycetaceae
  JOURNAL   DNA Res 17 (6), 393-406 (2010)
   PUBMED   21059706
  REMARK    DOI:10.1093/dnares/dsq026
REFERENCE   2  (bases 1 to 8783278)
  AUTHORS   Ichikawa,N., Watanabe,Y., Nakamura,S., Katano,Y., Oguchi,A.,
            Ankai,A., Yashiro,I., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Ikeda,H., Ishikawa,J., Horinouchi,S., Ohnishi,Y.,
            Hayakawa,M., Nihira,T., Kitani,S., Kuzuyama,T., Arisawa,A.,
            Nomoto,F., Miura,H., Takahashi,Y. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2009) Contact:Director-General Department of
            Biotechnology National Institute of Technology and Evaluation, NITE
            Genome Analysis Center (NGAC), Department of Biotechnology; 2-49-10
            Nishihara, Shibuya-ku, Tokyo 151-0066, Japan URL
            :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000269985.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:32:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,713
            CDSs (total)                      :: 7,605
            Genes (coding)                    :: 7,487
            CDSs (with protein)               :: 7,487
            Genes (RNA)                       :: 108
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 25 of 118
            Pseudo Genes (incomplete)         :: 95 of 118
            Pseudo Genes (internal stop)      :: 9 of 118
            Pseudo Genes (multiple problems)  :: 11 of 118
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:33:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2504042
            Orig. end                         :: 2527571
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP010968.1.
            'Otoguro, M. is at NITE Biological Resource Center (NBRC). Ikeda,
            H., Miura, H. and Takahashi Y. are at Kitasato Institute for Life
            Science. Ishikawa, J. is at National Institute of Infectious
            Diseases. Horinouchi, S., Ohnishi, Y. and Kuzuyama, T. are at The
            University of Tokyo. Hayakawa, M. is at University of Yamanashi.
            Nihira, T. and Kitani, S. are at Osaka University. Arisawa A. is at
            Mercian Corp. Nomoto F. is at Nagase & Co. Ltd. The other authors
            are at NITE Genome Analysis Center (NGAC).
            Please visit our web site. URL:http://www.bio.nite.go.jp/
            DOGAN ; Database of Genomes Analyzed at NITE. The database contains
            genome sequence data, physical maps and the genomic and proteomic
            data of the microorganisms analyzed.
            URL:http://www.bio.nite.go.jp/dogan/Top
            The microbial strain and microbial genomic DNA clones used for the
            sequencing project are available through the NBRC.
            URL:http://www.nbrc.nite.go.jp/e/index.html.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23529
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="16"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..23529
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23529
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:18529](+)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..18529
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(473..1498)
                     /locus_tag="KSE_RS11110"
                     /old_locus_tag="KSE_22620"
     CDS             complement(473..1498)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="KSE_RS11110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22620"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_014135398.1"
                     /transl_table=11
                     /translation="MDSAPRTRPQPEEPDDLSRAVYLHCLVHEGSDAHAVCRALDLSAA
                     EAEAAIAVLLELRLLRAVGPHGVLVPVSPQSAAADLIEPWQQEVQERQQRMAVVGDRIR
                     GYVGTYADFLNGHTPTGSSFRVDDRGSLVQRLREAAHACRGELLVLRPADSAPADSGDL
                     LADTEDAVLSGLAPDVELRVLTQHAARSSPAARSGLHGLHQAGAEIRTTADVPLRLLLF
                     DRELAVLFAEPDDPGCATVVTDPRIASFLGTLHDRMWDTAAAFIRRADEAAPRLDAGDL
                     RTAILELLSAGHSDDAIARKLAISLRTCRRHVSELLTTLDARTRFQAGVEAVRLGLVPT
                     P"
     gene            1727..3043
                     /locus_tag="KSE_RS11115"
                     /old_locus_tag="KSE_22630"
     CDS             1727..3043
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (2-277). E-value:
                     7.4e-20. Score: 63.1. Matches aSDomain:
                     nrpspksdomains_KSE_RS11115_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.5"
                     /locus_tag="KSE_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22630"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_033260248.1"
                     /sec_met_domain="Condensation (E-value: 1.2e-19, bitscore:
                     69.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFPLTAEQRSMLFLDGVFGPGIFHNVSFGAAVPAGTSEEAVRT
                     AIAALTSRHDGLLSRSVGSSPFLQAVSRETVEPVSRGLSGNSLEAEFDRLRSDLHNIPL
                     APSRARFDIIKNDAGDPLQVLGTVDHLVADGYSGGLLGNDLSALLAGRPTESTGSFPEI
                     ALARAVGDREAAAEIAHWRRAAAGTRPLAGIVRRAGPRAAWVRAQVDREVPGGEAHRRL
                     RELVQACRATPFAVLAAVTAVAVWRRSGRSAFLLHTPVSTRRDAVERATAGNFVMDRPI
                     PCRIDPGEPLSALVGRVQAAVWRAARYARLSVPELLCAVPEYGAALLEDGADYLQLHVD
                     VQSADATGVLSSPGGSTGVRTLGPFAPAHDLTVTTLRFRFSESRLFTRVFSGGSPDGIR
                     DAEELCADALAVFDAIAQPGDTARELADRLDRAEVPNPV"
     aSDomain        1733..2557
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS11115_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="7.40E-20"
                     /label="KSE_RS11115_Condensation_LCL.1"
                     /locus_tag="KSE_RS11115"
                     /protein_end="277"
                     /protein_start="2"
                     /score="63.1"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHLVADG"
                     /tool="antismash"
                     /translation="AFPLTAEQRSMLFLDGVFGPGIFHNVSFGAAVPAGTSEEAVRTAI
                     AALTSRHDGLLSRSVGSSPFLQAVSRETVEPVSRGLSGNSLEAEFDRLRSDLHNIPLAP
                     SRARFDIIKNDAGDPLQVLGTVDHLVADGYSGGLLGNDLSALLAGRPTESTGSFPEIAL
                     ARAVGDREAAAEIAHWRRAAAGTRPLAGIVRRAGPRAAWVRAQVDREVPGGEAHRRLRE
                     LVQACRATPFAVLAAVTAVAVWRRSGRSAFLLHTPVSTRRDAVERATAGNFVM"
     CDS_motif       2114..2170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KSE_RS11115_0001"
                     /evalue="2.50E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="KSE_RS11115"
                     /protein_end="148"
                     /protein_start="129"
                     /score="16.9"
                     /tool="antismash"
                     /translation="HLVADGYSGGLLGNDLSAL"
     gene            3073..3318
                     /locus_tag="KSE_RS11120"
                     /old_locus_tag="KSE_22640"
     CDS             3073..3318
                     /NRPS_PKS="Domain: PP-binding (20-71). E-value: 1.9e-12.
                     Score: 39.3. Matches aSDomain:
                     nrpspksdomains_KSE_RS11120_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.5"
                     /locus_tag="KSE_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22640"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_014135400.1"
                     /sec_met_domain="PP-binding (E-value: 5.3e-10, bitscore:
                     38.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTATADEFTRFLRPYCRELPPDRALTDDTLLVEVGIDSLLVVEL
                     VTAIEDHYGIEFPEELLAPDTFTTPGTLRLALEPLL"
     aSDomain        3133..3285
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS11120_PP-binding.1"
                     /evalue="1.90E-12"
                     /label="KSE_RS11120_PP-binding.1"
                     /locus_tag="KSE_RS11120"
                     /protein_end="71"
                     /protein_start="20"
                     /score="39.3"
                     /tool="antismash"
                     /translation="PPDRALTDDTLLVEVGIDSLLVVELVTAIEDHYGIEFPEELLAPD
                     TFTTPG"
     gene            3315..4916
                     /locus_tag="KSE_RS11125"
                     /old_locus_tag="KSE_22650"
     CDS             3315..4916
                     /NRPS_PKS="Domain: AMP-binding (31-447). E-value: 2e-51.
                     Score: 166.8. Matches aSDomain:
                     nrpspksdomains_KSE_RS11125_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.5"
                     /locus_tag="KSE_RS11125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22650"
                     /product="AMP-binding protein"
                     /protein_id="WP_014135401.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-53, bitscore:
                     179.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPELLLRGPDRALRRPRPLDLRATVAGRVHRQAARTPGRTAVW
                     DRGTAVDYAGLDAAVRRHTAALRAAGCASGEAVLVQGPRSATAIAVLLAMESLGCVHVP
                     LDPGWPAERIAEVARHCGATRLVRHGGPAGPAPRGLRLVALAEEPGTEGVEGADGADEA
                     AGLPAPRERASAAEPRYALYTAEFAGGAEGAVTAHAGMVNHLWAKIDDLGLTSADRVAY
                     SAPQVFDTAVWQMLAPLLVGGAVAVVAEADTAFPRRLAGALDRTGATVVELVPTAIGWL
                     LDRAGKAAGAPPPGSGLRLLVATGGELGPELAARIGAVLPGVATVFANGPVECSDDVLH
                     HRVRPADLAGARIPRGRPIPNAVLSAVLPAPDGAWRHAEPGEIGELLVQGAPVGLGHLA
                     DGVLRTGAYLRDTTPDAGPTGLAFRTGDLVSFHAGEVRYHGRADRQLALPGGRLALEDV
                     ERELQRHPGVRRCAVLAAEHDGAPALAVFYTAADPGDPPGERTAVPGHPELRLSWTLLP
                     VLPLTRKGEVDHRALR"
     aSDomain        3408..4655
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS11125_AMP-binding.1"
                     /evalue="2.00E-51"
                     /label="KSE_RS11125_AMP-binding.1"
                     /locus_tag="KSE_RS11125"
                     /protein_end="447"
                     /protein_start="31"
                     /score="166.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HRQAARTPGRTAVWDRGTAVDYAGLDAAVRRHTAALRAAGCASGE
                     AVLVQGPRSATAIAVLLAMESLGCVHVPLDPGWPAERIAEVARHCGATRLVRHGGPAGP
                     APRGLRLVALAEEPGTEGVEGADGADEAAGLPAPRERASAAEPRYALYTAEFAGGAEGA
                     VTAHAGMVNHLWAKIDDLGLTSADRVAYSAPQVFDTAVWQMLAPLLVGGAVAVVAEADT
                     AFPRRLAGALDRTGATVVELVPTAIGWLLDRAGKAAGAPPPGSGLRLLVATGGELGPEL
                     AARIGAVLPGVATVFANGPVECSDDVLHHRVRPADLAGARIPRGRPIPNAVLSAVLPAP
                     DGAWRHAEPGEIGELLVQGAPVGLGHLADGVLRTGAYLRDTTPDAGPTGLAFRTGDLVS
                     FHAGEVRYHGRADRQLA"
     gene            5001..5861
                     /locus_tag="KSE_RS11130"
                     /old_locus_tag="KSE_22660"
     CDS             5001..5861
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135402.1"
                     /locus_tag="KSE_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22660"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_014135402.1"
                     /sec_met_domain="phosphonates (E-value: 4.7e-95, bitscore:
                     316.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 2.3e-110,
                     bitscore: 366.7, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.8e-63, bitscore:
                     212.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRVNHQSFRTVLAESDVVRVAGAHHALSGYLAQEAGFQAVWSSS
                     FEVSASRCLPDASILSMTEYLEAAANIQKALSIPVVADCDTGYGDNLNVAHMVHEFEGA
                     GITAVCIEDKLFPKMNSFVGSGQALLDTAGFAAKIRTAKNAQHSSDFFVIARTEALISG
                     LDVTQALERCRAYADSGADAVLVHSKQRTKDQVMAFLDGWDGRVPVVIVPTTYPDWHID
                     EVRAAGVSVVIYANQGLRASVSSLRDAYGAIVRDGDTTGIEESIASVGDLFELQRLAEW
                     QKLGA"
     gene            5906..6889
                     /gene="sbnA"
                     /locus_tag="KSE_RS11135"
                     /old_locus_tag="KSE_22670"
     CDS             5906..6889
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135403.1"
                     /locus_tag="KSE_RS11135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22670"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_014135403.1"
                     /sec_met_domain="PALP (E-value: 2.9e-54, bitscore: 183.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVVTGAHELLDTEVFVDLAPQLGVNLHLKCEGLNFAGSVKIRAA
                     AWMVAEAERAGRIGPDTTLVESSSGNLGVAMAVVAAARNLRFHCVTDTKCNPSTIRLMR
                     ALGAVVDVVDRPAADGGGLLAARKARVRALCARDGGYLWLNQYENEASWLAHYHHTGPA
                     LAKEFSSLDVLFVGVGTGGTLTGCARYFRDHHPGVRVVAVDAEGSVNFGGRPGPRYIPG
                     LGAAEPMPLVDGAPVDRVLWVPEADTVRMCRRLAARGLLLGGSSGTVVSAAAAWLEAED
                     PDRALTAVAIAPDLGERYLDTVYDDDWVTRHFGAAAAAPHTRELLV"
     gene            6886..8553
                     /locus_tag="KSE_RS11140"
                     /old_locus_tag="KSE_22680"
     CDS             6886..8553
                     /NRPS_PKS="Domain: AMP-binding (55-462). E-value: 4.3e-87.
                     Score: 284.3. Matches aSDomain:
                     nrpspksdomains_KSE_RS11140_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135404.1"
                     /locus_tag="KSE_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22680"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_014135404.1"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-91, bitscore:
                     304.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPRTTTTTTTTTTTTAEPAALPMRPEAAAAAAALALRRPRPVR
                     LDRPVHAYVLDTARRDPGRTAVTDAGRSVDYRTLARRAAALADRLDRDGLRRGGVLAAA
                     GPRSADTVTVFLAAERLGAVYLPVDPAWPAARTADVLRRSGAALLLDYTGAPDGPAATA
                     AAGAGVPVTGLRDTDTEADPAPPDDPGAPADPAYLIFTSGTTGVPKGAVVERRGLLNHL
                     RAKLDDLALTAEDTLAFTAPLVFDISVWQMLAPLLAGGTVAVVRDAELAHPRRLAAALG
                     RTGATVAELVPTMAGWLADEASRPGGTRPALRTLISTGEELRPEAARRIAAAFPGTALL
                     NAYGPTECSDDVTHHRVTAADLGLPRLPVGRPIANAVLHVLVADPDGRWRPAAPGEAGD
                     LFVGGLPVGRGYVNDPAATARAFFADPIDPDSPTGRLYRTGDLARIEDGVVHYLGRDDR
                     QVKVAGVRMELDEVELALARHPALAQCAVTAAGDDLAAHYVPRSPVTPAELRAFLRELL
                     PAGQVPRSWHRHERLPLTANGKTDHRLLAEADRREGHR"
     aSDomain        7051..8271
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS11140_AMP-binding.1"
                     /evalue="4.30E-87"
                     /label="KSE_RS11140_AMP-binding.1"
                     /locus_tag="KSE_RS11140"
                     /protein_end="462"
                     /protein_start="55"
                     /score="284.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DTARRDPGRTAVTDAGRSVDYRTLARRAAALADRLDRDGLRRGGV
                     LAAAGPRSADTVTVFLAAERLGAVYLPVDPAWPAARTADVLRRSGAALLLDYTGAPDGP
                     AATAAAGAGVPVTGLRDTDTEADPAPPDDPGAPADPAYLIFTSGTTGVPKGAVVERRGL
                     LNHLRAKLDDLALTAEDTLAFTAPLVFDISVWQMLAPLLAGGTVAVVRDAELAHPRRLA
                     AALGRTGATVAELVPTMAGWLADEASRPGGTRPALRTLISTGEELRPEAARRIAAAFPG
                     TALLNAYGPTECSDDVTHHRVTAADLGLPRLPVGRPIANAVLHVLVADPDGRWRPAAPG
                     EAGDLFVGGLPVGRGYVNDPAATARAFFADPIDPDSPTGRLYRTGDLARIEDGVVHYLG
                     RDDRQVKV"
     CDS_motif       7471..7527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KSE_RS11140_0001"
                     /evalue="1.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="KSE_RS11140"
                     /protein_end="214"
                     /protein_start="195"
                     /score="26.5"
                     /tool="antismash"
                     /translation="AYLIFTSGTTGVPKGAVVE"
     CDS_motif       8065..8151
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KSE_RS11140_0002"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="KSE_RS11140"
                     /protein_end="422"
                     /protein_start="393"
                     /score="30.5"
                     /tool="antismash"
                     /translation="PGEAGDLFVGGLPVGRGYVNDPAATARAF"
     CDS_motif       8239..8304
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KSE_RS11140_0003"
                     /evalue="3.90E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="KSE_RS11140"
                     /protein_end="473"
                     /protein_start="451"
                     /score="25.6"
                     /tool="antismash"
                     /translation="YLGRDDRQVKVAGVRMELDEVE"
     gene            8550..9713
                     /locus_tag="KSE_RS11145"
                     /old_locus_tag="KSE_22690"
     CDS             8550..9713
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_5"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135405.1"
                     /locus_tag="KSE_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22690"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_014135405.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 5.4e-61, bitscore:
                     205.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSADARPRTDRLPPHARLLLTMARLHLDPDRLDLVRALADRPD
                     LDWGAFTDAAARHKLLPLVGRHVHRHRLDRKGPGTFPYPWVFTGAYLANRERNHALADE
                     FGLIFRELGAAGIRYAVRKGFPLAEGEYGDPALRRMTDLDLLIDRADAARAREVLERLG
                     YLQGNLAADGERVEPFSRDTQLFWRLNLSQQLPFRKSGHRAAVPEFDVDLTHDIFQKKS
                     GRTAPAAELLDRAVPRTVCGVDAWVQGPEDRLLDLCSHLHKEATSLFFIGENIDLQLAK
                     FLDVALVVAGLDEDGWGAFLARVEEYDAAAIVYYALHYVDQLYPEAVPAAVLDRLRPAD
                     LGYLDEFGDLDGRRARWSMEFLPRLFHSGRREEGSASAVPLTTGAGA"
     gene            9710..11683
                     /locus_tag="KSE_RS39880"
                     /old_locus_tag="KSE_22700"
     CDS             9710..11683
                     /NRPS_PKS="Domain: Aminotran_5 (327-607). E-value: 5.1e-24.
                     Score: 76.8. Matches aSDomain:
                     nrpspksdomains_KSE_RS39880_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012488.5"
                     /locus_tag="KSE_RS39880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22700"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_014135406.1"
                     /sec_met_domain="Aminotran_5 (E-value: 6.9e-16, bitscore:
                     56.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPAAPGRVPELLVLKVGGSLFSDKRGGGGTDPRAVADYARQVR
                     DLAAARPGRVVLVTGGGAACHEVGRTVDPARDPWSALALTAPAFAVRWEWTSQLRRLGV
                     RAVPLQLTGLYGEHPDGTEETHPAAVRRLLAEHALPVLSSDCALTADGTLRIVSSDEAP
                     ALLLGEDPYAVRIVALTDVPGVLTGPDDTSPVLRRLDAADPAAADHLLWPTGSWDATGA
                     MRGKIDALAAHARRGAQCVITRGGRTGDLGHLFDPLEDWPEHLPYTEIATDRIVPARTV
                     LLNPGPVNVHPRVRAAIGSPDECHREPEAAALLTAVARKTTEVAGGGADTHATVLLTGS
                     GTAALEAAISSAVPPDGRLLVLDNGHYGERLHAIAATHRIPAVRLEFGWASPVDLAAVD
                     RALAADPGITHVAVVHHETSTGMLNPVAEIGRITAEHGRSLVVDAISSLGAEALDVVAD
                     RIDWCVGTANKCLEGLPGISFVTAPRARFEELAGRPARTFYLDLHANYRAQVGSASPQF
                     TPAVQVLRALDAALDLTLAEGVAARSARYAARAAAVRAGLAERGVRLLLPPEQCATSLT
                     NAFLDDGLGYQQLHDGLKERGYVVYATQSAAAGVFRIANMGQLTDRDVQGLLSAFDEVR
                     KEHADAAAPHQPPHPLPRKETR"
     aSDomain        10691..11530
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS39880_Aminotran_5.1"
                     /evalue="5.10E-24"
                     /label="KSE_RS39880_Aminotran_5.1"
                     /locus_tag="KSE_RS39880"
                     /protein_end="607"
                     /protein_start="327"
                     /score="76.8"
                     /tool="antismash"
                     /translation="GADTHATVLLTGSGTAALEAAISSAVPPDGRLLVLDNGHYGERLH
                     AIAATHRIPAVRLEFGWASPVDLAAVDRALAADPGITHVAVVHHETSTGMLNPVAEIGR
                     ITAEHGRSLVVDAISSLGAEALDVVADRIDWCVGTANKCLEGLPGISFVTAPRARFEEL
                     AGRPARTFYLDLHANYRAQVGSASPQFTPAVQVLRALDAALDLTLAEGVAARSARYAAR
                     AAAVRAGLAERGVRLLLPPEQCATSLTNAFLDDGLGYQQLHDGLKERGYVVYATQSAA"
     gene            11680..13956
                     /locus_tag="KSE_RS11155"
                     /old_locus_tag="KSE_22710"
     CDS             11680..13956
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135407.1"
                     /locus_tag="KSE_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22710"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_014135407.1"
                     /transl_table=11
                     /translation="MTPPSPTQPSPAQSGAEQSGPTRLAVVGGGPTCTYVLERLAALTR
                     RPDAGTELEIVVYDRSGEFGSGKVHSPRQSRTSYLNRIVGQVAFGADESVVDAGPLLPA
                     ADRPTLLEWCRDRFAATGDAAYDLVAEDWPKRYLHGEALQDRFRRYVDLLRATPGVTVD
                     LRQAEVVDLAEDGDRLALLTADGADPYRADLVLMLTGHSSNDPALEARTAGWAAFAAEH
                     GSTLIASAYPLEHSLEVPGTGPGNTVACLGMGLTGIDVILYLTEGRGGTFEPGEDGRLV
                     YRRSGREPDSVVAFSRNGLFTFARPFNQKERDIAALEYRGAFLTVPAVGELRRTVGRPA
                     LLGGREQRQLDFERHLFPLIVLEMALIQYGTLYGPEFRAAAVEAARPGYDKFLADADAF
                     PDHRAAAAALTAPLDELAAATAAAVDRVLDGADPLDGGRPAPAGLELAPLVRSFLTVVH
                     GAETADRLLERAGDPTAFAAAVAAAVSPYRHAARAAGHAFSWERTIDPVPRGSYRTAAG
                     YREALLDFLDRDIRWAAQGNLDNPAKAAADAAWRDLRGVVIEAVDFGGLRAGSHRTFLE
                     VYTGHHNRLCQGASREAMEKVRALIEAGLVDVSLGPDTEVSCDAATGRFRIGGAVTGAH
                     RLADTLVDARVHGFDAARDVRPIYPNLLRRGLVRKWANPGLDEPDFVPGGLDLTPEFHP
                     YRADGRVERRITVLGPPSEGVMYHQIGALRPHKDHHVLRDILSWTNAFLPRPAEPGDRP
                     ERTDA"
     gene            13953..14633
                     /locus_tag="KSE_RS43800"
                     /old_locus_tag="KSE_22720"
     CDS             13953..14633
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135408.1"
                     /locus_tag="KSE_RS43800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22720"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_014135408.1"
                     /transl_table=11
                     /translation="MNDLDPAVQFADISDAHRALLAEKLTESQARAAIELPGWTRAHVL
                     IHLADLSQAFARQARYAAKGELIEVYDGGRPTRDRRIEELHGRPAEWLNERLAEGLAAL
                     EESWAALSEDDWQRPCAYRDSPLWATRLAWWRESALHLVDLDVGRRSEQWSAELSGHVV
                     EFLQSRLPAGTRLEAVDTGRTWGEGRTVRGSLRALAAWISGRPAAERPAAVDGGPLPEL
                     TAWP"
     gene            14630..15643
                     /locus_tag="KSE_RS43805"
                     /old_locus_tag="KSE_22730"
     CDS             14630..15643
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135409.1"
                     /locus_tag="KSE_RS43805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22730"
                     /product="FomB family phosphonate monophosphate kinase"
                     /protein_id="WP_063747485.1"
                     /transl_table=11
                     /translation="MSRPTPLDLSALPVRSTRTADLGLLTLQVTSNLEHFDGHAYFARD
                     AAEGTRPDYRVDCLDLDRDAFDPAEVAALADDSLRARRFRGGYYLSHIHGEPAYLRTDG
                     SRAYVFGRRLERTVWPYFVKRVLTDFAADRGYLHLKAAGFALGGGRATLLVGPNGGGKT
                     VFLSQACLAGARFLTNTHVLVREGVAHGVPTSVRIRRDDRFGPLIDRHGLTPHLESGDY
                     LAPAELVFGGRPVDRAVVRNVVVVDYNPRGRVGVEEIDPATAETFLSQYAHAVTTYGLK
                     DDVLAHQGRDVAAFSRVLGRMNRQLAGLVCSARCFRVNADLRDPAVRDAVLERLAG"
     gene            15749..16717
                     /locus_tag="KSE_RS11170"
                     /old_locus_tag="KSE_22740"
     CDS             15749..16717
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (127-300). E-value: 1.6e-22. Score:
                     72.4. Matches aSDomain: nrpspksdomains_KSE_RS11170_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135410.1"
                     /locus_tag="KSE_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22740"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_014135410.1"
                     /sec_met_domain="TauD (E-value: 2.1e-20, bitscore: 72.4,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIASPDARTLAVPAEAIHTFGPEAQREIAARVAELTAATAGRRI
                     DDLTDAEVGLDRMPRFRAEIEATREIIDTRVHFIVYDRVEGVDSLRGQALYAWLLGSAL
                     GRPMVQNHQGWRFIEVYDRGNQGTVEQGARYHQTKQGAHMHNDAVNDPEPIDYLLLSCG
                     QSAYLGGESILVDARSVHETLKAYPEVLDVLTGDFWFEKRGMTTAEDGFFRSPVISYSP
                     GGEALVRYFRTYMEGAHEKLGVPMDDRQRAALDFFDAVLDQSGVQYRIRLERGQTLVSA
                     DDRFLHSRTAFVDRYEPREIDLDTDRPDRVNRYMFRMWSRK"
     aSDomain        16130..16648
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KSE_RS11170_TauD.1"
                     /evalue="1.60E-22"
                     /label="KSE_RS11170_TauD.1"
                     /locus_tag="KSE_RS11170"
                     /protein_end="300"
                     /protein_start="127"
                     /score="72.4"
                     /tool="antismash"
                     /translation="TVEQGARYHQTKQGAHMHNDAVNDPEPIDYLLLSCGQSAYLGGES
                     ILVDARSVHETLKAYPEVLDVLTGDFWFEKRGMTTAEDGFFRSPVISYSPGGEALVRYF
                     RTYMEGAHEKLGVPMDDRQRAALDFFDAVLDQSGVQYRIRLERGQTLVSADDRFLHSRT
                     AFVDRYEPRE"
     gene            16714..17370
                     /locus_tag="KSE_RS11175"
                     /old_locus_tag="KSE_22750"
     CDS             16714..17370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135411.1"
                     /locus_tag="KSE_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22750"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_014135411.1"
                     /transl_table=11
                     /translation="MTSGPYREIATEDELRELIAPPNPVVHRKSADRFGPLERAWIARS
                     PFCVLATSGADGDCDVSPRGDPPGFAHVLGDRLLALPDRPGNRRADSWRNLLGNPRVAL
                     LFVVPGRGDTLRVNGRGRLVTDAPFLADLAHRGHVPTLALLVEPEEVYFHCAKSFLRAR
                     LWEPDSWDPDAVPSRARIAGATEWTDTPLAELEERYGPGYARQLYGTPSPTDPSP"
     gene            17385..17909
                     /locus_tag="KSE_RS11180"
                     /old_locus_tag="KSE_22760"
     CDS             17385..17909
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135412.1"
                     /locus_tag="KSE_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22760"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_014135412.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 4.9e-09, bitscore:
                     34.8, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTALDTRAARALLTGLVDHGFTLATGVPCSLLAGAFTLLEDTG
                     SDPDLAGLRYVPAPREDSAIGIASGAAVAGERAVVLMQNSGLGYSLNVLTSFNLIYDVP
                     VLLVVSWRGHDGNDAVEHDVIGAELLNLLDLFALPHTVLDHADVAGSVTAVLAQMEQHG
                     RCSVLVVREGI"
     gene            17909..18529
                     /locus_tag="KSE_RS11185"
                     /old_locus_tag="KSE_22770"
     CDS             17909..18529
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014794.5"
                     /locus_tag="KSE_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22770"
                     /product="thiamine pyrophosphate-dependent enzyme"
                     /protein_id="WP_014135413.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-18, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLTLSEIALELLRRHPDAVIVSTCGFTSRELFNAADRPENFYL
                     VGSMGMAAPIALGIALARPGRTVIALDGDGSLLMNLNVLPLLAAAGADLLHVVADNGMH
                     ESTGGQRTVQQADFTALARAAGYPHTVLVTDADELRAARLGPGLTLLHVLTGPRTAGAG
                     RRVTHTPQELVSRVRTALAAPAPTTPTTPAAPARGTVLAGAAA"
     gene            18526..19566
                     /gene="sbnB"
                     /locus_tag="KSE_RS11190"
                     /old_locus_tag="KSE_22780"
     CDS             18526..19566
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135414.1"
                     /locus_tag="KSE_RS11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22780"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_014135414.1"
                     /transl_table=11
                     /translation="MNAAPAFSVIPGRQVHQVLAGRESEVVDVVERAYRLHGDGRTVNP
                     DSYFLRFPDRPSSRIIALPASVGGEVDVHGIKWIAGFPENVADGLPRASAVLILNDTRT
                     GYPFACLESSIISAARTAGSAALAADRLSRARGVRPARIGFVGTGLIARYLFDHLAAIG
                     FDTTRVGVHDSVPAHAEGFRDYLAAAGATAELHSTTESLVRSSDLLVIATVAPAPHLTD
                     PAWFDHHPLVLNISLRDLGPDVILGAYNVLDDVDHCLKAGTSPHLAEQRAGHRDFVDGT
                     LYDHLAGDRAVPADRTVVFSPFGLGVLDLALAKHVHDRLAATGQLEDVPGFFHDLQRHE
                     APPTAG"
     gene            19563..20432
                     /locus_tag="KSE_RS11195"
                     /old_locus_tag="KSE_22790"
     CDS             19563..20432
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013088.5"
                     /locus_tag="KSE_RS11195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22790"
                     /product="EamA family transporter"
                     /protein_id="WP_014135415.1"
                     /transl_table=11
                     /translation="MTPPQAALPGLPVAVVLAAGLLHAAWNTLAKAARDRDAGLTLISV
                     TKTALCLPLLLLLTPPAAASWPYLAASAAVHAAYMAQLSRAYRLGDFGQVYPVARGVAP
                     VGVAAVAVLLLGEHFGPWRLGGLLAVCGGLAALSLNGVPGGRAIGGPAVRAALATGGWI
                     AAYTLIDAVGVRRSGDAFGYTAWMAALEGVLVALLMPRLRRRPLADLLRPERLRSTAGG
                     LVATLSYGAVLWAQTRAPAAEVAALRETGIIWAALIGAALFGEPLGRRRLCAGAVVVAG
                     VVLLGATH"
     misc_feature    20616..20630
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.04"
                     /tool="antismash"
     misc_feature    20622..20638
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.9"
                     /tool="antismash"
     misc_feature    20624..20637
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.92"
                     /tool="antismash"
     misc_feature    20625..20638
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.06"
                     /tool="antismash"
     misc_feature    complement(20627..20640)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.01"
                     /tool="antismash"
     gene            20679..20918
                     /locus_tag="KSE_RS11200"
                     /old_locus_tag="KSE_22800"
     CDS             20679..20918
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135416.1"
                     /locus_tag="KSE_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22800"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_014135416.1"
                     /transl_table=11
                     /translation="MEIFNGMAADGIEAAAPWQKAQLSVGTGSCVEFRALDDGETVAVR
                     NSRFPGGPALLFTRSEVEAMLDGARNGEFDHLAR"
     misc_feature    complement(20977..20989)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            21030..22001
                     /locus_tag="KSE_RS11205"
                     /old_locus_tag="KSE_22810"
     CDS             21030..22001
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="KSE_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22810"
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /protein_id="WP_014135417.1"
                     /transl_table=11
                     /translation="MAVDTFHSDRGGGAARPWAEAALLLGAHLEVSRGNRTQSEVVAAT
                     GKLVSPSYYSRIERGDIRIDKPHLIPLILDAQGIGPGEHRDRLVELAFAASQEGWAARF
                     RSGNRMAVPETMLRLTSLEESATELFVVDRNAIPGQLQTEAYSRLITRYTLPASLQDAG
                     LQEVVVGLRAERRHRFAERLATDRPKARFFIEQSVLHADFGRPEILIDQLQALLDLVED
                     RSLPVGIRVMTVRIPLAIPINTLTRLGFRRSVADSVPDVIYNELGRQAAFHRGSLPGAN
                     EVADPGYVDLNDLIDNVLLRAPGFQESRRLIQNALLEAQLRL"
     gene            complement(22040..22870)
                     /locus_tag="KSE_RS11210"
                     /old_locus_tag="KSE_22820"
     CDS             complement(22040..22870)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF016550.5"
                     /locus_tag="KSE_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_22820"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_014135418.1"
                     /transl_table=11
                     /translation="MNRNGTGWQEPIDRGRPSVARIKDCLLGGNRNYPADQRAVAELLE
                     TAPNARELARAGHDFLIRTARHLAEKHDIRQYLDHGSGLPLPALNLHEVVGAVHRDARV
                     VYTDTDPMVLAYGRAVLDESPNAVILDADLTDTARITAGLDGRIDLRRPVGVLLASAFH
                     RIPGRDGDDPKAAVGELIGLLAPGSFVALCQLVSDDDDARAALTGLMRRQTGEEWGRAR
                     TEADVRSYFDLDRLALEGPGLGDVTAWHPDAPPRGSESRPAATWTAFGGLARVV"
     gene            complement(23078..23506)
                     /locus_tag="KSE_RS11215"
                     /old_locus_tag="KSE_22830"
     CDS             complement(23078..23506)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_22830"
                     /product="hypothetical protein"
                     /protein_id="WP_014135419.1"
                     /transl_table=11
                     /translation="MSIPPVGYAAFVELHLCHYEMYALARLGDARLAGRVVELVLRRTE
                     ADWAWVLRDDPAAATWRTLREAVTLARKDAPASPSDGLHRSMPERPADAALLHEHLGLA
                     PADAAALMGLEEPAVRAHLKAAHRWRADRGPAGPAGAA"
ORIGIN
        1 ctggcgacac cgggctggaa cgcggcggtc gcggtgccgc tgagcgcggc caggcccatc
       61 agcagccaca gcggggggtg gccgacggcg aacgaggcgg cggcgcagcc ctggaccagc
      121 agccggagcg cgtcggcgcc gatcatcatc cggcgggggg tgaagcggtc ggcgagcacg
      181 ccgccgaaga gcacgaacac cgccagcggg agcatctggg aggcgaggac gtagccgact
      241 ccggaggcgc cgtagccgag cgagaccacg ccgtacatca gggcgaccgg cagcatcgcg
      301 tcgccgagca gcgagacgag ccgggcggtg aagtagtagc ggaagtcccg ggtccacagc
      361 gggacggcgg ggcggccggc cggctcgtcg gcggtcgcgg gggtgggggt gggggtggcc
      421 atgggcgggt ccgttcggtc ggtgccgggg aagggcgggg aggaaggagt ggtcaggggg
      481 tggggaccag tccgaggcgg accgcctcga cgccggcctg gaagcgggtg cgggcgtcga
      541 gggtggtgag cagttcggag acgtgccggc ggcaggtgcg cagcgagatg gcgagcttgc
      601 gggcgatcgc gtcgtcggag tggccggccg acagcagttc gaggatggcc gtgcggaggt
      661 cgcccgcgtc gagccggggc gccgcctcgt cggcgcgtcg gatgaacgcc gccgcggtgt
      721 cccacatccg gtcgtgcagg gtcccgagga aggaggcgat ccgggggtcg gtgaccacgg
      781 tggcgcaccc cgggtcgtcg ggttcggcga acagcacggc gagttcgcgg tcgaagagca
      841 ggaggcggag cgggacgtcg gcggtggtgc ggatctcggc gccggcctgg tgcaggccgt
      901 gcagcccgga ccgggccgcc gggctggacc gggcggcgtg ctgggtgagc acccggagct
      961 ccacgtcggg ggcgaggccg gagagcacgg cgtcctcggt gtccgcgagc aggtcgccgg
     1021 agtcggcggg cgccgagtcc gccgggcgca gcacgaggag ttcgccgcgg caggcgtgcg
     1081 cggcctcgcg cagccgctgg acgagcgagc cccggtcgtc gacccggaag ctggacccgg
     1141 tcggcgtgtg cccgttcagg aagtcggcgt aggtgccgac gtagccgcgg atccggtcgc
     1201 cgacgaccgc catccgctgc tggcgctcct gcacctcctg ctgccacggt tcgatcaggt
     1261 ccgcggcggc ggactgcggc gacaccggca ccaggacgcc gtgcgggccg accgcgcgca
     1321 gcagccggag ctccagcagc acggcgatcg ccgcctcggc ctccgccgcc gacaggtcga
     1381 gcgcccggca gacggcgtgc gcgtcgctgc cctcgtgcac caggcagtgc aggtagaccg
     1441 cgcgtgacag gtcgtcgggc tcttccggtt gcggtctcgt cctgggtgct gagtccatcg
     1501 aggatccccc ttatccggtg actgtccact tctgtccctg cacttccttg ccacacgggc
     1561 ggcgttgtga cgagggaacc gcccgctcaa gaatgggtgc agagccaatc ggagggtagc
     1621 gagcggcgga tagcccgaca aggcttgtcc gctggtgtgt caagttcgcg atcccttgtc
     1681 cgagcgcgct cgcaaggtgt cctccgtgcc ggaagaaggt gctcgggtga gtgcatttcc
     1741 cttgaccgct gagcagcgca gcatgctgtt tctcgacggg gtcttcgggc ccggcatatt
     1801 ccacaatgtc agctttgggg cagccgtccc cgcgggcacc tccgaggagg ccgtccgcac
     1861 cgcgatcgcc gccctgacca gcaggcatga tgggctgctc agccgctcgg tcggctcctc
     1921 gccgttcctc caggcggtct cccgggagac ggtcgagccg gtttcgcgag ggctctccgg
     1981 gaattccctg gaggcggagt tcgaccgcct ccgcagcgat cttcacaata tccccctggc
     2041 gccttcgagg gcgcgtttcg acatcatcaa aaacgatgcc ggagaccctc tccaggtact
     2101 cgggacggtc gatcacctgg tggccgacgg gtattccgga gggctgctcg gaaacgacct
     2161 ttcggcgctt ctcgcgggcc gtccgacgga atccaccggg agctttccgg aaatcgccct
     2221 ggcccgcgcg gtcggcgacc gggaggccgc ggcggaaatc gcccactggc gccgggcggc
     2281 ggccgggacg cggccgctcg cgggaatcgt ccggcgggcc gggccgcgcg ccgcgtgggt
     2341 gcgcgcccag gtggaccgcg aggtgccggg cggggaggcc caccggcggc tgcgcgagct
     2401 ggtgcaggcg tgccgggcca cccccttcgc ggtgctggcc gcggtcaccg cggtcgcggt
     2461 ctggcggcgc tccggccgtt cggccttcct gctgcacacg ccggtctcca cccggcggga
     2521 cgcggtggag cgggccacgg ccggcaactt cgtgatggac cgtccgatcc cgtgccggat
     2581 cgaccccggg gagccgctgt ccgcgctggt cggacgggtg caggccgccg tgtggcgggc
     2641 ggccaggtac gcccggctga gcgtgccgga actgctgtgc gcggtgcccg agtacggggc
     2701 ggccctgctg gaggacggcg ccgactacct gcagctgcac gtggacgtgc agagcgccga
     2761 cgccaccggc gtgctgagca gtcccggggg gtcgaccggg gtgcgcaccc tgggtccgtt
     2821 cgcgccggcc cacgacctca cggtgacgac gctgcggttc cggttcagcg agtcccgact
     2881 gttcacccgg gtgttctccg ggggttcacc ggacggtatc cgcgacgccg aagaactgtg
     2941 cgccgacgca ttggcggtct tcgacgcgat tgcgcaaccc ggcgacaccg caagggaact
     3001 ggcggaccga ctggatcggg ccgaggttcc gaatcccgtg tgaattgtct agaccataga
     3061 ggagattccg ccatggacac cgctaccgcc gacgagttca cccgtttcct ccgcccgtac
     3121 tgccgcgaac tgccgcccga ccgcgcgctg accgacgaca ccctgctggt cgaggtcggc
     3181 atcgactccc tgctcgtggt ggaactggtc accgcgatcg aggaccacta cgggatcgag
     3241 ttcccggagg aactgctcgc ccccgacacc ttcaccaccc ccggcaccct gcggctcgcc
     3301 ctggagccgc tgctgtgacc acccccgagc tcctgctgcg cggccccgac cgggcgctgc
     3361 gccgcccgcg gccgctggac ctgcgggcca ccgtggccgg ccgggtccac cggcaggccg
     3421 cccgcacccc cggccgcacc gccgtgtggg accgcggcac cgccgtcgac tacgccgggc
     3481 tggacgccgc ggtgcggcgc cacaccgcgg cgctgcgcgc ggcgggctgc gcctcgggcg
     3541 aggccgtcct ggtccagggg ccgcgctcgg ccaccgcgat cgccgtcctg ctggcgatgg
     3601 agagcctcgg ctgcgtgcac gtcccgctcg accccggctg gccggccgag cggatcgccg
     3661 aggtggcccg gcactgcggc gccacccggc tggtccggca cggcggcccc gccgggccgg
     3721 cgccccgggg gctgcgcctc gtcgccctgg cggaggagcc cggcacggag ggcgtcgagg
     3781 gtgcggacgg cgcggacgag gcggccgggc tgccggcgcc gcgcgagcgg gcctccgccg
     3841 ccgaaccccg gtacgcgctc tacaccgccg agttcgccgg tggcgccgag ggcgcggtga
     3901 cggcccacgc cggcatggtg aaccacctct gggcgaagat cgacgacctc ggtctgacct
     3961 cagcggaccg ggtcgcctac agcgcgccgc aggtgttcga caccgccgtg tggcagatgc
     4021 tcgccccgct gctggtcggg ggcgcggtcg cggtggtcgc cgaggccgac acggccttcc
     4081 cccgccggct ggccggcgcc ctggaccgca cgggtgccac cgtggtggag ctggtgccca
     4141 cggccatcgg ctggctgctc gaccgcgccg gcaaggccgc cggcgcaccg ccgcccggca
     4201 gcgggctgcg gctgctggtg gcgaccggcg gggagctcgg cccggagctg gccgcgcgga
     4261 tcggcgccgt cctgcccggt gtcgccacgg tgttcgccaa cgggccggtc gagtgctcgg
     4321 acgacgtgct gcaccaccgg gtgcggcccg ccgacctggc gggggcccgg atcccccggg
     4381 ggcgcccgat ccccaacgcg gtgctctccg ccgtgctgcc ggcgccggac ggcgcctggc
     4441 gccacgccga acccggcgag atcggcgaac tcctggtcca gggcgccccg gtgggcctcg
     4501 gccacctcgc cgacggcgtc ctgcgcaccg gcgcctacct gcgcgacacc accccggacg
     4561 ccgggccgac cgggctggcc ttccgtaccg gcgacctggt gtccttccac gccggcgagg
     4621 tccgctacca cggccgcgcc gaccgccaac tcgccctccc cggcgggcgg ttggccctgg
     4681 aggacgtcga gcgcgaactc cagcgccacc ccggcgtccg gcgctgcgcg gtgctcgccg
     4741 ccgagcacga cggcgccccc gcgctcgcgg tgttctacac cgccgccgac cccggcgacc
     4801 cgcccgggga gcggaccgcc gtgcccgggc acccggagct gcggctgagc tggaccctgc
     4861 tgcccgtcct gccgctgacc cgcaagggcg aggtcgacca ccgggcgctg cgctgagccc
     4921 cggctcagcc cgccggtccg accccttccg tccgtccgtt ccttcccttc cacgccccca
     4981 ccacccacag gagatccgtc gtgttgcgtg tcaaccacca gtccttccgc accgttctcg
     5041 ccgagtcgga cgtcgtccgc gtcgccgggg cgcaccacgc gctcagcggc tacctggccc
     5101 aggaggcggg cttccaggcc gtctggtcgt ccagcttcga ggtgtcggcc tcccgctgcc
     5161 tgcccgacgc cagcatcctg agcatgaccg agtacctgga ggcggcggcc aacatccaga
     5221 aggcgctgag catcccggtg gtcgccgact gcgacaccgg ctacggcgac aacctcaacg
     5281 tggcgcacat ggtccacgag ttcgagggcg ccgggatcac cgcggtctgc atcgaggaca
     5341 agctgttccc gaagatgaac agcttcgtcg gcagcggcca ggccctgctg gacaccgccg
     5401 gcttcgccgc caagatccgc accgccaaga acgcccagca cagctccgac ttcttcgtca
     5461 tcgcccgcac cgaggcgctg atcagcggcc tcgacgtcac ccaggcgctg gagcgctgcc
     5521 gcgcctacgc cgactccggc gcggacgccg tgctggtgca ctccaagcag cgcaccaagg
     5581 accaggtgat ggccttcctg gacggctggg acggccgcgt cccggtggtc atcgtgccca
     5641 ccacctaccc cgactggcac atcgacgagg tgcgggcggc cggggtctcc gtggtgatct
     5701 acgccaacca gggcctgcgc gccagcgtct cctcgctgcg cgacgcctac ggcgcgatcg
     5761 tccgggacgg cgacaccacc ggcatcgagg agtccatcgc ctcggtcggc gacctgttcg
     5821 agctccagcg gctcgccgag tggcagaagc tcggtgcctg agccccgccg gccggtcgga
     5881 ccgcctccga ggaaaggcag ttgacgtgcc agtcgtcacc ggtgcccacg aactactcga
     5941 caccgaggtc ttcgtggacc tcgccccgca gctcggcgtc aacctccacc tgaagtgcga
     6001 ggggctcaac ttcgccggct cggtcaagat cagggccgcg gcgtggatgg tcgcggaggc
     6061 cgagcgggcc ggccggatcg gcccggacac caccctggtg gagtcctcct ccggcaacct
     6121 cggcgtcgcc atggcggtgg tcgcggccgc ccgcaacctc cgcttccact gcgtcaccga
     6181 caccaagtgc aacccgtcca cgatccggct gatgcgcgcg ctcggcgcgg tcgtcgacgt
     6241 ggtcgaccgg cccgccgcgg acggcggcgg gctgctggcg gcccggaagg cccgggtgcg
     6301 ggcgctgtgc gcccgggacg gcggctacct gtggctcaac cagtacgaga acgaggcgag
     6361 ttggctcgcc cactaccacc acaccggccc ggcgctggcc aaggagttca gctcgctcga
     6421 cgtgctgttc gtcggggtcg gcaccggtgg gacgctcacc ggctgcgccc gctacttccg
     6481 cgaccaccac cccggtgtgc gggtggtcgc ggtggacgcc gagggctccg tcaacttcgg
     6541 cggccggccc ggcccccggt acatcccggg gctcggcgcc gccgagccga tgccgctggt
     6601 cgacggcgcg ccggtcgacc gggtgctgtg ggtgccggag gccgacaccg tccggatgtg
     6661 ccggcggctc gccgcccgcg gcctgctgct cggcggctcc tcgggcaccg tggtcagcgc
     6721 cgccgccgcc tggctggagg ccgaggaccc ggaccgcgcc ctcaccgccg tggccatcgc
     6781 cccggacctc ggcgagcgct acctcgacac cgtctacgac gacgactggg tcacccggca
     6841 cttcggcgcg gccgccgccg caccgcacac cagggagctg ctcgtatgac cgcgccccgc
     6901 accaccacca cgaccaccac gacgaccacc accaccgcgg agccggccgc gctgccgatg
     6961 cgcccggaag ccgccgcggc ggccgcggcc ctggccctgc gccggccccg cccggtcagg
     7021 ctcgaccggc cggtccacgc gtacgtgctg gacaccgcgc gccgcgaccc cgggcgcacc
     7081 gccgtgaccg acgccggccg gtccgtcgac taccgcacgc tggcccgccg ggccgccgcg
     7141 ctcgccgacc ggctcgaccg ggacggcctg cggcgcggcg gggtgctcgc cgccgccggg
     7201 ccgcgcagcg ccgacaccgt gacggtgttc ctcgccgccg aacggctcgg cgcggtctac
     7261 ctgccggtcg acccggcctg gccggccgcc cgcaccgccg acgtgctgcg ccgctccggc
     7321 gcggccctgc tgctcgacta cacgggggcg ccggacggtc cggccgcgac ggccgccgcc
     7381 ggggcgggcg tcccggtgac cgggctgcgg gacaccgaca ccgaggccga cccggcaccg
     7441 ccggacgacc cgggcgcgcc cgccgacccc gcgtacctga tcttcacctc cgggaccacc
     7501 ggcgtgccca agggcgcggt ggtggaacgg cgcggcctgc tcaaccacct ccgggccaag
     7561 ctcgacgacc tggcgctcac cgccgaggac acgctggcct tcaccgcccc gctggtcttc
     7621 gacatctcgg tctggcagat gctcgcgccg ctgctggccg gcggcaccgt cgcggtcgtc
     7681 cgggacgccg aactcgccca cccgcgacgg ctggccgccg ccctgggacg caccggcgcg
     7741 acggtcgccg agctggtgcc caccatggcc ggctggctgg ccgacgaggc gagccggccg
     7801 ggcggcaccc ggcccgcgct gcggacgctg atctccaccg gcgaggagct gcgccccgaa
     7861 gcggcccggc ggatcgccgc cgccttcccc ggcaccgcgc tgctgaacgc ctacggcccc
     7921 accgagtgct cggacgacgt gacgcaccac cgggtcaccg ccgccgacct ggggctgccc
     7981 cggctgccgg tcgggcggcc gatcgccaac gccgtgctgc acgtcctggt cgccgacccg
     8041 gacggccgct ggcggcccgc cgcaccgggc gaggccggcg acctgttcgt cggcggcctg
     8101 ccggtcggcc gcggctacgt caacgacccg gcggccaccg cgcgggcgtt cttcgccgac
     8161 ccgatcgacc cggactcccc caccggccgg ctctaccgga ccggcgacct ggcccggatc
     8221 gaggacggcg tcgtccacta cctcggccgc gacgaccggc aggtcaaggt cgccggggtg
     8281 cggatggaac tcgacgaggt cgaactcgcc ctggcccggc accccgcgct cgcccagtgc
     8341 gcggtcaccg ccgccggcga cgacctcgcc gcccactacg tgccccggag cccggtcacc
     8401 cccgccgagc tgcgcgcctt cctgcgggag ctgctgcccg ccgggcaggt gccgcgcagc
     8461 tggcaccgac acgaacggct cccgctcacc gccaacggaa agaccgacca ccgcctcctc
     8521 gccgaggccg accgccgaga gggccaccga tgaccaccag cgccgacgcc cgcccccgga
     8581 ccgaccggct gccgccgcac gcccggctcc tgctcaccat ggcccggctc cacctggacc
     8641 cggaccggct cgacctggtc cgcgccctcg ccgaccggcc cgacctcgac tggggcgcgt
     8701 tcaccgacgc cgccgcccgg cacaagctgc tgccgctggt cggccggcac gtgcaccgcc
     8761 accgcctcga ccgcaagggc cccggcacct tcccgtaccc gtgggtgttc accggcgcgt
     8821 acctggccaa ccgggagcgc aaccacgcgc tggccgacga gttcgggctg atcttccggg
     8881 agctcggggc cgccgggatc aggtacgccg tccgcaaggg cttcccgctc gccgagggcg
     8941 agtacggcga tccggcgctg cgccggatga ccgacctcga cctgctgatc gaccgcgccg
     9001 acgccgcccg ggcccgggag gtgctggaac gcctcggcta cctccagggc aacctcgccg
     9061 ccgacggcga acgggtggag ccgttcagcc gggacaccca gctgttctgg cggctgaacc
     9121 tcagccagca gctgccgttc cgcaagagcg gccaccgggc ggcggtgccc gagttcgacg
     9181 tcgacctgac gcacgacatc ttccagaaga agtcgggccg caccgcgccc gccgccgagc
     9241 tgctcgaccg ggccgtgccg cgcaccgtgt gcggcgtcga cgcctgggtg cagggcccgg
     9301 aggaccggct gctcgacctc tgctcgcacc tccacaagga ggccaccagc ctgttcttca
     9361 tcggcgagaa catcgacctg cagctcgcca agttcctcga cgtcgccctc gtcgtggccg
     9421 gcctcgacga ggacgggtgg ggggccttcc tggcccgggt cgaggagtac gacgccgccg
     9481 cgatcgtcta ctacgcgctg cactacgtcg accagctgta cccggaggcc gtccccgccg
     9541 ccgtgctgga ccggctgcgc ccggccgacc tcggctacct cgacgagttc ggcgacctgg
     9601 acggccggcg cgcccgctgg tcgatggagt tcctgccccg gctgttccac tccggccggc
     9661 gcgaggaggg cagcgcctcc gccgtcccgc tgaccaccgg ggccggcgcg tgagcgcccc
     9721 ggcggcgccc ggccgcgtcc ccgagctgct ggtgctgaag gtcggcggca gcctgttctc
     9781 cgacaagcgc ggcggtggcg gcaccgaccc gcgggccgtc gccgactacg cccgccaggt
     9841 gcgcgacctg gcggccgccc ggccgggccg ggtggtgctg gtcaccggcg ggggcgccgc
     9901 ctgccacgag gtcggccgga ccgtcgaccc ggcccgcgac ccctggtccg ccctcgccct
     9961 caccgcgccc gcgttcgcgg tccgctggga gtggacctcc cagctgcgcc ggctgggcgt
    10021 ccgcgccgtg ccgctccagc tcaccggcct gtacggggag caccccgacg gcaccgagga
    10081 gacccacccg gccgccgtcc ggcggctgct cgccgagcac gccctgccgg tgctctccag
    10141 cgactgcgcg ctcaccgccg acggcaccct gcggatcgtc agcagtgacg aggccccggc
    10201 cctgctgctc ggcgaggacc cgtacgccgt ccggatcgtc gcgctgaccg acgtccccgg
    10261 cgtcctcacc ggacccgacg acaccagccc ggtgctgcgc cggctggacg ccgccgaccc
    10321 ggccgccgcc gaccacctgc tgtggcccac cggctcctgg gacgccaccg gcgcgatgcg
    10381 cggcaagatc gacgcgctgg ccgcgcacgc ccgccgcggc gcccagtgcg tgatcacccg
    10441 gggcgggcgc accggggacc tcggccacct cttcgacccg ctggaggact ggccggaaca
    10501 cctgccgtac accgagatcg ccaccgaccg gatcgtcccc gcccgcaccg tgctgctcaa
    10561 ccccgggccg gtgaacgtcc acccccgggt gcgcgccgcg atcggctcgc ccgacgagtg
    10621 ccaccgcgaa ccggaggccg ccgcgctgct cacggcggtc gcccggaaga ccaccgaggt
    10681 ggccggcggc ggcgccgaca cccacgccac cgtgctgctc accggctccg gcaccgccgc
    10741 gctggaggcc gcgatcagct ccgccgtgcc cccggacggc cggctcctgg tcctcgacaa
    10801 cggccactac ggcgagcggc tgcacgccat cgccgcgacc caccggatcc cggccgtgcg
    10861 gctggagttc ggctgggcga gcccggtcga cctcgccgcg gtcgaccgcg cgctcgccgc
    10921 cgacccgggc atcacgcacg tcgccgtggt ccaccacgag accagcaccg ggatgctcaa
    10981 cccggtggcc gagatcggcc ggatcaccgc cgaacacggc cgcagcctgg tggtcgacgc
    11041 gatcagcagc ctcggcgcgg aggccctcga cgtggtcgcc gaccggatcg actggtgcgt
    11101 gggcaccgcc aacaagtgcc tggagggact gcccgggatc agtttcgtca ccgccccccg
    11161 cgcccggttc gaggaactcg ccggacggcc cgcccgcacc ttctacctcg acctgcacgc
    11221 caactaccgg gcccaggtcg gctccgccag cccgcagttc accccggccg tgcaggtgct
    11281 gcgcgccctc gacgcggcgc tcgacctcac cctggccgaa ggcgtcgccg cccgctccgc
    11341 ccgctacgcg gcccgcgccg cggccgtccg ggccggcctc gccgagcgcg gcgtccgcct
    11401 gctgctgccg cccgagcagt gcgccacctc gctcaccaac gccttcctcg acgacggcct
    11461 cggctaccag caactgcacg acggcctcaa ggagcgcggc tacgtcgtct acgccaccca
    11521 gagcgccgcc gccggagtgt tccggatcgc caacatgggc cagctcaccg accgcgacgt
    11581 ccagggcctg ctcagcgcgt tcgacgaggt ccgcaaggag cacgccgacg cggccgcccc
    11641 ccaccagccc ccgcaccccc tcccccggaa ggagacccgg tgacaccgcc cagccccacc
    11701 cagcccagcc ccgcccagtc cggcgcggag cagtccggcc ccacccgcct cgccgtggtc
    11761 ggcggcggac cgacctgcac ctacgtgctg gaacgcctcg ccgcgctgac ccgccggccg
    11821 gacgccggca ccgagctgga gatcgtcgtc tacgaccggt ccggcgagtt cggctccggc
    11881 aaggtgcaca gcccccggca gagccgcacc agctacctca accggatcgt cggccaggtc
    11941 gccttcggcg ccgacgagag cgtggtcgac gccggcccgc tgctgcccgc cgccgaccgc
    12001 ccgaccctgc tcgaatggtg ccgcgaccgg ttcgccgcga ccggtgacgc ggcctacgac
    12061 ctggtcgccg aggactggcc caagcgctac ctgcacggcg aggccctgca ggaccgcttc
    12121 cgccgctacg tcgacctgct gcgcgccacc ccgggcgtca ccgtcgacct gcggcaggcc
    12181 gaggtcgtcg acctggcgga ggacggcgac cggctggcgc tgctcaccgc ggacggcgcc
    12241 gacccgtacc gggccgacct ggtcctgatg ctgaccggcc actcgtccaa cgacccggcg
    12301 ctggaggccc gcaccgccgg ctgggcggcg ttcgccgccg agcacggcag caccctgatc
    12361 gcctccgcgt acccgctgga gcactcgctg gaggtccccg gcaccgggcc cgggaacacc
    12421 gtggcctgcc tgggcatggg cctgaccggc atcgacgtga tcctctacct caccgagggc
    12481 cgcggcggca ccttcgagcc cggcgaggac ggccggctgg tgtaccggcg cagcggccgc
    12541 gaaccggact cggtggtcgc cttcagccgc aacggcctgt tcaccttcgc ccggccgttc
    12601 aaccagaagg agcgcgacat cgcggcgctg gagtaccgcg gcgcgttcct caccgtcccc
    12661 gccgtcggcg aactgcgccg cacggtcggc cggccggccc tgctcggcgg ccgggagcag
    12721 cgccaactcg acttcgagcg gcacctgttc ccgctgatcg tgctggagat ggcgctgatc
    12781 cagtacggca cgctgtacgg cccggagttc cgggcggcgg ccgtggaggc ggcccggccc
    12841 ggctacgaca agttcctcgc ggacgccgac gccttccccg accaccgggc cgccgcggcc
    12901 gcgctgaccg ccccgctgga cgaactggcc gccgccaccg ccgccgcggt cgaccgggtg
    12961 ctggacggcg ccgacccgct cgacggcggc cgccccgccc cggcgggcct ggaactcgcc
    13021 ccgctggtgc ggagcttcct gaccgtggtg cacggggccg agaccgccga ccggctgctc
    13081 gaacgggccg gcgacccgac cgcgttcgcc gccgcggtgg ccgccgcggt ctccccgtac
    13141 cggcacgccg cccgggccgc cgggcacgcc ttctcctggg agcggaccat cgacccggtg
    13201 ccgcgcggca gttaccgcac cgcggccggg taccgggagg cgctgctcga cttcctcgac
    13261 cgggacatcc gctgggccgc ccagggcaac ctggacaacc cggcgaaggc cgccgccgac
    13321 gcggcctggc gcgacctgcg cggcgtggtg atcgaggcgg tcgacttcgg cgggctgcgg
    13381 gccgggtccc accgcacctt cctggaggtc tacaccggcc accacaaccg gctctgccag
    13441 ggcgcctcgc gggaggcgat ggagaaggtg cgggcgctga tcgaggccgg cctggtcgac
    13501 gtctcgctcg gcccggacac cgaggtctcc tgcgacgccg ccaccggcag gttccggatc
    13561 ggcggggcgg tcaccggcgc gcaccggctc gccgacaccc tggtcgacgc ccgggtgcac
    13621 ggcttcgacg ccgcccgcga cgtgcggccg atctacccca acctgctgcg ccgcggcctg
    13681 gtccggaagt gggccaaccc gggcctggac gagccggact tcgtgccggg cggcctcgac
    13741 ctcaccccgg agttccaccc gtaccgggcc gacggccggg tggagcggcg gatcaccgtc
    13801 ctcggcccgc cgagcgaggg ggtgatgtac caccagatcg gtgcgctgcg cccccacaag
    13861 gaccaccatg tcctacggga catcctgtcc tggaccaacg ccttcctgcc ccgcccggcc
    13921 gagccgggcg accgccccga aaggaccgac gcatgaacga cctcgacccc gcggtgcagt
    13981 tcgccgacat ctccgacgcc caccgcgccc tgctcgcgga gaagttgacg gagagccagg
    14041 ccagggcggc gatcgagctg cccggctgga cccgggccca cgtgctgatc cacctggccg
    14101 acctgtcgca ggcgttcgcc cggcaggccc ggtacgccgc caagggcgag ctgatcgagg
    14161 tgtacgacgg cggccggccg acccgggacc gccggatcga ggagctgcac ggccgcccgg
    14221 ccgagtggct gaacgagcgg ctggccgagg ggctggcggc gctggaggag tcctgggcgg
    14281 cgctgtccga ggacgactgg cagcgtccct gcgcctaccg cgactcgccg ctgtgggcga
    14341 cccggctggc ctggtggcgg gagagcgccc tgcacctggt cgacctggac gtcggccgcc
    14401 ggagcgagca gtggagcgcc gaactgtccg gccacgtcgt ggagttcctc cagtcgcggc
    14461 tgcccgcggg cacccggctg gaggccgtcg acaccggccg gacctggggc gagggacgga
    14521 cggtgcgcgg cagtctgcgg gcgctggcgg cctggatctc cggccggccc gcggccgagc
    14581 ggccggcggc cgtcgacggc ggtccgctgc ccgagctgac ggcgtggccg tgagccgccc
    14641 gacccccctc gacctctccg cgctcccggt ccgctccacc cggaccgcgg acctgggcct
    14701 gctgaccctc caggtcacca gcaacctcga acacttcgac gggcacgcct acttcgcccg
    14761 cgacgccgcc gagggcaccc gccccgacta ccgggtggac tgcctcgacc tcgaccggga
    14821 cgccttcgac ccggccgagg tggcggccct cgcggacgac tcgctgcggg cccgccggtt
    14881 ccgcggcggg tactacctca gccacatcca cggcgagccc gcctacctgc gcaccgacgg
    14941 cagccgggcg tacgtcttcg gccggcggct ggagcggacg gtgtggccgt acttcgtgaa
    15001 gcgggtcctg accgacttcg cggcggaccg cggctacctg cacctgaagg ccgccgggtt
    15061 cgcgctgggc gggggccggg cgaccctgct ggtcgggccg aacggcggcg gcaagaccgt
    15121 cttcctctcc caggcgtgcc tggccggggc gcgcttcctc accaacaccc acgtgctggt
    15181 gcgggagggc gtcgcccacg gggtgccgac ctcggtgcgg atccgccggg acgaccggtt
    15241 cgggccgctg atcgaccggc acggcctgac cccgcacctg gagagcggcg actacctcgc
    15301 cccggccgaa ctggtcttcg gcggccgccc ggtggaccgg gcggtggtgc gcaacgtggt
    15361 cgtcgtcgac tacaacccgc gcggccgggt gggcgtcgag gagatcgacc cggccaccgc
    15421 cgagaccttc ctctcccagt acgcgcacgc cgtcaccacc tacgggctga aggacgacgt
    15481 gctggcccac cagggccgcg acgtggcggc gttcagccgg gtgctggggc ggatgaaccg
    15541 ccagctggcc ggcctggtgt gcagcgcgcg ctgcttccgc gtcaacgccg acctgcgcga
    15601 cccggccgtc cgggacgcgg tgctggagcg cctggccggc tgacccgccc cgcccccgct
    15661 cccccgcgct cccctgcacg gcccctccct ccttcccgac ccttcccgac ccttcccgac
    15721 cattcaccgg aaagtgatgg acatgtccat ggcaatagcg tccccggacg cccgcacgct
    15781 cgccgtcccc gccgaggcga tccacacctt cggccccgag gcccagcgcg agatcgccgc
    15841 ccgcgtcgcc gaactgaccg ccgccacggc cggccgccgg atcgacgacc tcaccgacgc
    15901 ggaggtcggc ctcgaccgga tgccccggtt ccgcgccgag atcgaggcca cccgcgagat
    15961 catcgacacc cgggtccact tcatcgtcta cgaccgggtc gagggcgtgg acagcctccg
    16021 cggccaggcc ctctacgcct ggctgctggg cagcgcgctc ggccgcccga tggtgcagaa
    16081 ccaccagggc tggcggttca tcgaggtcta cgaccggggc aaccagggga ccgtcgagca
    16141 gggcgcccgg taccaccaga ccaagcaggg cgcgcacatg cacaacgacg ccgtcaacga
    16201 ccccgagccg atcgactacc tgctgctctc ctgcggccag agcgcctacc tgggcggcga
    16261 gtccatcctg gtggacgccc gctcggtgca cgagacgctc aaggcgtacc cggaggtcct
    16321 ggacgtcctg accggggact tctggttcga gaagcgcggc atgaccaccg ccgaggacgg
    16381 cttcttccgc tccccggtga tcagctacag ccccgggggc gaggccctgg tccgctactt
    16441 ccgcacctac atggagggcg cccacgagaa gctcggcgtc cccatggacg accgccagcg
    16501 ggccgccctc gacttcttcg acgcggtgct cgaccagtcc ggcgtgcagt accggatccg
    16561 gctggagcgc ggccagaccc tggtctccgc cgacgaccgc ttcctgcact ccaggaccgc
    16621 cttcgtcgac cggtacgagc cgcgcgagat cgacctcgac accgaccggc ccgaccgggt
    16681 caaccggtac atgttccgga tgtggtcccg gaagtgacct ccggaccgta ccgggagatc
    16741 gccaccgagg acgagctgcg cgagctgatc gccccgccca acccggtggt ccaccgcaag
    16801 agcgccgacc gcttcggccc gctggaacgc gcctggatcg cccggtcccc gttctgcgtg
    16861 ctggccacct ccggggccga cggcgactgc gacgtctccc cgcgcggcga cccgcccggc
    16921 ttcgcgcacg tcctcggcga ccggctgctc gccctcccgg accggcccgg caaccggcgc
    16981 gccgacagct ggcgcaacct gctcggcaac ccgcgggtcg cgctgctgtt cgtcgtcccc
    17041 ggccgcggcg acaccctgcg ggtcaacggc cgcggccgcc tggtcaccga cgcccccttc
    17101 ctcgccgacc tcgcccaccg cggccacgtc ccgaccctgg ccctgctggt cgaacccgag
    17161 gaggtctact tccactgcgc caagtccttc ctgcgcgccc ggctctggga acccgacagc
    17221 tgggacccgg acgccgtccc ctcccgggcc cggatcgccg gcgccaccga gtggaccgac
    17281 acccccctcg ccgaactcga agaacgctac ggcccgggct acgcccggca gctctacggc
    17341 accccgtccc cgaccgaccc gtccccctga aggaaggacc cacgatgtcc ggcaccgccc
    17401 tcgacacccg cgccgcccgc gccctgctga ccggcctggt cgaccacggt ttcaccctcg
    17461 ccaccggcgt cccctgcagc ctgctcgccg gcgccttcac cctgctcgaa gacaccggct
    17521 ccgacccgga cctggccggc ctgcgctacg tccccgcccc gcgcgaggac agcgccatcg
    17581 gcatcgcctc cggggccgcg gtggccggcg agcgcgccgt ggtgctgatg cagaactccg
    17641 gcctcggcta ctccctcaac gtgctgacct cgttcaacct gatctacgac gtccccgtgc
    17701 tcctggtggt cagctggcgc ggacacgacg gcaacgacgc cgtcgagcac gacgtgatcg
    17761 gcgccgaact gctcaacctg ctcgacctgt tcgcactccc gcacaccgtc ctcgaccacg
    17821 ccgacgtggc cggctcggtg accgcggtcc tcgcccagat ggaacagcac ggccgctgct
    17881 ccgtcctcgt cgtccgggaa ggcatctgat gtcccagctc acgctctccg agatcgccct
    17941 cgaactgctc cgccggcacc ccgacgcggt gatcgtctcc acctgcggct tcaccagccg
    18001 cgaactcttc aacgccgccg accggccgga gaacttctac ctggtcggct cgatgggcat
    18061 ggccgcgccg atcgcgctcg gcatcgccct cgcccggccc ggccgcaccg tcatcgcgct
    18121 cgacggcgac ggctcgctgc tgatgaacct caacgtgctc ccgctgctcg ccgccgccgg
    18181 cgccgacctg ctgcacgtgg tcgccgacaa cgggatgcac gagagcaccg gcggccagcg
    18241 caccgtccag caggccgact tcaccgcgct ggcccgggcc gccgggtacc cccacaccgt
    18301 cctggtcacc gacgccgacg aactgcgcgc cgcccggctc ggccccggac tcaccctgct
    18361 gcacgtcctg accggcccgc gcaccgccgg cgccggccgc cgggtcaccc acaccccgca
    18421 ggaactggtc agccgggtcc gcaccgccct cgccgcgccc gcccccacca cgcccaccac
    18481 tcccgccgcg cccgcccgcg gcaccgtcct cgccggagcc gccgcgtgaa cgccgccccc
    18541 gccttctcgg tcatccccgg ccgccaggtc caccaggtgc tggccggacg ggagtcggag
    18601 gtcgtcgacg tcgtcgagcg cgcctaccgc ctgcacggcg acggacgcac cgtcaacccc
    18661 gactcctact tcctgcgctt ccccgaccgg ccgtcctccc ggatcatcgc gctgcccgcc
    18721 tcggtcggcg gcgaggtcga cgtgcacggc atcaagtgga tcgccggctt cccggagaac
    18781 gtcgccgacg gactgccccg cgcctccgcg gtgctcatcc tcaacgacac caggaccggc
    18841 taccccttcg cctgcctgga gagctccatc atcagcgcgg cccgcaccgc cggctccgcc
    18901 gcgctggccg ccgaccggct cagccgcgcc cgcggcgtac ggccggcccg gatcggcttc
    18961 gtcggcaccg gcctgatcgc ccgctacctc ttcgaccacc tcgccgccat cggcttcgac
    19021 accacccggg tcggcgtcca cgacagcgtc cccgcccacg ccgagggctt ccgcgactac
    19081 ctcgccgcgg ccggcgccac cgccgaactg cactccacca ccgagtccct ggtccgctcc
    19141 agcgacctgc tggtgatcgc cacggtggcc cccgccccgc acctcaccga ccccgcctgg
    19201 ttcgaccacc acccgctggt gctcaacatc tcgctgcgcg acctcgggcc cgacgtcatc
    19261 ctcggcgcct acaacgtgct cgacgacgtc gaccactgcc tcaaggccgg cacctccccg
    19321 cacctcgccg aacagcgggc cgggcaccgc gacttcgtcg acggcacgct ctacgaccac
    19381 ctcgccgggg accgcgccgt ccccgcggac cggaccgtgg tcttctcccc gttcggcctc
    19441 ggcgtgctcg acctcgcgct ggccaagcac gtccacgacc gactcgccgc caccggacaa
    19501 ctggaggacg tccccgggtt cttccacgac ctgcagcggc acgaggcccc gccgaccgcc
    19561 ggatgacgcc cccgcaggcc gccctcccgg gcctcccggt cgccgtggtc ctcgccgccg
    19621 ggctgctgca cgccgcctgg aacaccctgg ccaaggccgc ccgcgaccgg gacgccgggc
    19681 tcaccctgat cagcgtcacc aagaccgcgc tctgcctgcc gctgctgctc ctgctcaccc
    19741 cgcccgccgc ggcgagctgg ccctacctgg ccgcctccgc ggcggtgcac gccgcctaca
    19801 tggcccaact ctcccgcgcc taccggctcg gcgacttcgg ccaggtctac ccggtcgccc
    19861 gcggcgtcgc cccggtcggc gtcgcggcgg tcgccgtcct gctcctcggc gagcacttcg
    19921 gcccctggcg gctgggcgga ctgctcgccg tctgcggcgg actcgccgcc ctctccctga
    19981 acggcgtccc gggcgggcgc gcgatcggcg gcccggccgt ccgggccgcc ctcgccaccg
    20041 gcgggtggat cgccgcctac accctgatcg acgccgtcgg ggtccggcgc tccggcgacg
    20101 ccttcggcta caccgcctgg atggccgccc tggagggcgt cctggtcgcc ctgctgatgc
    20161 cccggctgcg ccgccgcccg ctggccgacc tgctgcggcc cgaacgcctg cgctccaccg
    20221 ccggcggcct ggtcgccacc ctctcctacg gcgccgtcct ctgggcccag acccgcgccc
    20281 ccgccgccga ggtcgccgcc ctccgcgaga ccggcatcat ctgggccgcc ctgatcggcg
    20341 ccgcgctctt cggcgaaccc ctcggccgcc gccggctctg cgccggagcc gtcgtcgtgg
    20401 ccggcgtcgt cctgctcggc gccacccact gaccggccgc cgaccggacg cccgcaccgc
    20461 tcggaccgca ttgcggtcgg atcatatggc gttcataggt gtgccgggtt cggcggaatt
    20521 cacccgaccg tgtaatggcc cgtgaccctg gcaacggtga atgatgcgta ccgctcagct
    20581 gcggaatccc gcacgggatt ccgcagaccc cgatcggggc ctcattttca tatgacaaat
    20641 gaggtctggg tgccattcga tcatggagga ggactcgcat ggagatcttc aacggcatgg
    20701 cggcggacgg catcgaggcg gcggcgccgt ggcagaaggc ccagctcagc gtgggtaccg
    20761 ggtcctgcgt ggagttccgg gcgctggacg acggggagac ggtggcggtg cgcaacagcc
    20821 gctttcccgg cgggccggcg ctgctgttca cccgctccga agtcgaggcg atgctggacg
    20881 gcgcgcgcaa tggtgagttc gaccacctgg cgcgctgata ccaaccagtg ccgatttacc
    20941 gtacggatgg attgatgtga cgcccgggcc caccttgtgc aaaactcatc cgactggagt
    21001 agaggttggg ataaagcact ggggggccga tggccgtcga cacgttccac tccgaccgcg
    21061 ggggcggcgc ggctcggccg tgggccgagg ccgcgctgct cctgggcgcc cacctggagg
    21121 tctcccgggg gaaccgcacg cagagcgagg tggtggccgc gaccgggaaa ctggtcagcc
    21181 cctcgtacta cagccggatc gagcgcgggg acatcaggat cgacaagccg cacctgatcc
    21241 cgctcatcct ggacgcccag ggcatcgggc cgggggaaca ccgggaccgg ctggtggagt
    21301 tggcgttcgc cgcgtcgcag gagggctggg ccgccaggtt ccgcagcggg aaccggatgg
    21361 cggtgcccga gacgatgctc cggctgacct cgctggagga gtcggcgacc gagctgttcg
    21421 tggtggaccg caacgcgatc cccggccagc tgcagaccga ggcgtactcc cggctgatca
    21481 cccgctacac cctgcccgcc agcctccagg acgccgggct gcaggaggtg gtggtcggcc
    21541 tccgggccga acggcgccac cggttcgcgg agcggctggc caccgaccgg ccgaaggccc
    21601 ggttcttcat cgagcagtcc gtgctgcacg ccgacttcgg ccgccccgag atcctgatcg
    21661 accaactcca ggcgctgctc gacctggtgg aggaccggag cctgccggtc ggcatccggg
    21721 tgatgaccgt ccggatcccg ctggccatcc cgatcaacac cctgacccgg ctggggttcc
    21781 gccggtcggt ggccgactcg gtgcccgacg tcatctacaa cgagctgggg cggcaggcgg
    21841 ccttccaccg aggctcgctg ccgggggcca acgaggtggc cgacccgggc tacgtcgacc
    21901 tcaacgacct gatcgacaac gtgctgctgc gggcgcccgg cttccaggag agccgccggc
    21961 tgatccagaa cgcgctgctg gaggcccaac tacgcctgta gcggcgggga tcctcccggc
    22021 ggttcgggcc ggggagggtt cagacgaccc tggcgaggcc gccgaaggcg gtccaggtcg
    22081 cggccgggcg cgactccgag ccccggggcg gggcgtcggg gtgccaggcg gtgacgtcgc
    22141 cgaggccggg gccctccagg gccagccggt cgaggtcgaa gtagctccgg acgtcggcct
    22201 cggtgcgcgc gcggccccac tcctcgccgg tctgccgccg catcaggccg gtcagcgcgg
    22261 cgcgggcgtc gtcgtcgtcg ctgaccagtt ggcagagggc gacgaagctg cccggggcga
    22321 gcagtccgat cagctccccg acggcggcct tcgggtcgtc gccgtcccgg ccggggatgc
    22381 ggtggaacgc ggaggcgagc agcacgccga ccggccgccg gaggtcgatc cggccgtcga
    22441 ggccggcggt gatccgggcg gtgtcggtga ggtcggcgtc gaggatgacc gcgttggggc
    22501 tctcgtccag cacggcccgg ccgtaggcga ggaccatcgg gtcggtgtcg gtgtagacca
    22561 cccgggcgtc gcggtggacg gccccgacca cctcgtgcag gttgagggcg ggcagcggca
    22621 ggccggagcc gtggtcgagg tactgcctga tgtcgtgctt ctcggcgagg tggcgtgccg
    22681 tccggatcag gaagtcgtgg ccggcccggg ccagctcccg ggcgttgggg gcggtttcca
    22741 gcagctccgc gaccgcccgt tggtccgccg ggtagttgcg gttccctccg agcaggcagt
    22801 cctttatccg cgcgacgctt ggtctgcccc tgtcaatggg ctcttgccag ccggttccgt
    22861 tccggttcac ccgctacccc cagcatgatc cgaactttcg tgccagcgag caattatggc
    22921 gctccgtcac cgcgcaccgg gccggaaaag gccgaaactc acacccctgg gtgacagtgg
    22981 cgaaggcatg gcgaaagacc tggcgaaccg gggtacacct ggtcggttca ccaggcccgc
    23041 accaccgccc gccggcggac cggacggcga cgccgggtca ggcggccccg gccgggccgg
    23101 cggggccgcg gtcggcccgc cagcggtggg cggccttcag gtgggcgcgg acggcgggct
    23161 cctccagccc catcagcgcg gcggcgtcgg ccggggccag gccgaggtgc tcgtgcagga
    23221 gcgcggcgtc ggccggccgt tcgggcatgc tgcggtgcag gccgtccgac ggggaggccg
    23281 gcgcgtcctt ccgggccagc gtgacggcct cgcgcagggt ccgccaggtg gccgccgcgg
    23341 ggtcgtcgcg cagcacccag gcccagtcgg cctcggtccg gcgcagcacg agttcgacca
    23401 cccgcccggc gaggcgggcg tcgccgaggc gggccagcgc gtacatctcg tagtggcaga
    23461 ggtggagttc gacgaaagcg gcgtagccga cagggggtat ggacaccggg gctccgttcg
    23521 acgtcgacg
//
