LOCUS       NC_016109              21107 bp    DNA     linear   CON 11-DEC-2024
DEFINITION  Kitasatospora setae KM-6054, complete sequence.
ACCESSION   NC_016109
VERSION     NC_016109.1
KEYWORDS    RefSeq.
SOURCE      Kitasatospora setae KM-6054
  ORGANISM  Kitasatospora setae KM-6054
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Kitasatospora.
REFERENCE   1
  AUTHORS   Ichikawa,N., Oguchi,A., Ikeda,H., Ishikawa,J., Kitani,S.,
            Watanabe,Y., Nakamura,S., Katano,Y., Kishi,E., Sasagawa,M.,
            Ankai,A., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Nihira,T., Horinouchi,S., Ohnishi,Y., Hayakawa,M.,
            Kuzuyama,T., Arisawa,A., Nomoto,F., Miura,H., Takahashi,Y. and
            Fujita,N.
  TITLE     Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary
            snapshot of the family Streptomycetaceae
  JOURNAL   DNA Res 17 (6), 393-406 (2010)
   PUBMED   21059706
  REMARK    DOI:10.1093/dnares/dsq026
REFERENCE   2  (bases 1 to 8783278)
  AUTHORS   Ichikawa,N., Watanabe,Y., Nakamura,S., Katano,Y., Oguchi,A.,
            Ankai,A., Yashiro,I., Fukui,S., Hashimoto,Y., Kamata,S., Otoguro,M.,
            Tanikawa,S., Ikeda,H., Ishikawa,J., Horinouchi,S., Ohnishi,Y.,
            Hayakawa,M., Nihira,T., Kitani,S., Kuzuyama,T., Arisawa,A.,
            Nomoto,F., Miura,H., Takahashi,Y. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2009) Contact:Director-General Department of
            Biotechnology National Institute of Technology and Evaluation, NITE
            Genome Analysis Center (NGAC), Department of Biotechnology; 2-49-10
            Nishihara, Shibuya-ku, Tokyo 151-0066, Japan URL
            :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000269985.1-RS_2024_12_11
            Annotation Date                   :: 12/11/2024 11:32:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,713
            CDSs (total)                      :: 7,605
            Genes (coding)                    :: 7,487
            CDSs (with protein)               :: 7,487
            Genes (RNA)                       :: 108
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 78
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 25 of 118
            Pseudo Genes (incomplete)         :: 95 of 118
            Pseudo Genes (internal stop)      :: 9 of 118
            Pseudo Genes (multiple problems)  :: 11 of 118
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:33:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2376629
            Orig. end                         :: 2397736
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP010968.1.
            'Otoguro, M. is at NITE Biological Resource Center (NBRC). Ikeda,
            H., Miura, H. and Takahashi Y. are at Kitasato Institute for Life
            Science. Ishikawa, J. is at National Institute of Infectious
            Diseases. Horinouchi, S., Ohnishi, Y. and Kuzuyama, T. are at The
            University of Tokyo. Hayakawa, M. is at University of Yamanashi.
            Nihira, T. and Kitani, S. are at Osaka University. Arisawa A. is at
            Mercian Corp. Nomoto F. is at Nagase & Co. Ltd. The other authors
            are at NITE Genome Analysis Center (NGAC).
            Please visit our web site. URL:http://www.bio.nite.go.jp/
            DOGAN ; Database of Genomes Analyzed at NITE. The database contains
            genome sequence data, physical maps and the genomic and proteomic
            data of the microorganisms analyzed.
            URL:http://www.bio.nite.go.jp/dogan/Top
            The microbial strain and microbial genomic DNA clones used for the
            sequencing project are available through the NBRC.
            URL:http://www.nbrc.nite.go.jp/e/index.html.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="15"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            675..3131
                     /locus_tag="KSE_RS10505"
                     /old_locus_tag="KSE_21350"
     CDS             675..3131
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023418.5"
                     /locus_tag="KSE_RS10505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21350"
                     /product="DUF3488 and transglutaminase-like
                     domain-containing protein"
                     /protein_id="WP_014135276.1"
                     /transl_table=11
                     /translation="MTTRAKLTLCAALATALAALCLSPLFQDSFALAPHGLLMVAVAAG
                     AGAGLRALPLPRALVPPLQLLVVLYVLLLTTVRSAMAAGLLPGPGALDAVSTLLSQGGS
                     DVQEYAIPAPATDGLRLIVVGSVALIAVLVDALAVTYRRAAAAGLPLLALYSVAGGLVD
                     SPGGMWLWFLFGSAGYLALLYVEGQDRLTRWGRVFHGTGRSAVTLSNGGRRIGVIALAA
                     AVLLPVFVPAVGPGLFGGHGSGDGTGTGGGNGTMDQRSLNLVVALTANLRSNDDTQLLS
                     FSTDSPDPDQLYLRIAALSEFNGQEWLPGPQDPQPMPTTVPAPEGLSPNLPTSSVRTNI
                     TVADQLSTAWLPMPYPMSWVQLPSTSDWRFDPTGRTVSGVNGQKSKGLTYSVGSVAVGA
                     TAAQLRAAGPTPETVGKRYLGLPANLPAVVGETARTVTKGKTTPYDQAVALQQYFTGGG
                     FTYNTKIDARTGPDAIAKFLQDKEGFCVHFAATMAAMSRSLGIPARVAIGFTPGSGGGS
                     SRVVRSSNYHAWPELYFNGYGWMRFEPTPNRGSTPLYSVQQAAPSTAPSTAPSSAAPSE
                     QPSAQPSSSSSCPPQQHKLGDCADETALAERKTTTTAWWRSWTVLAGVLGGLLVAGLLA
                     FPMLWRTRLRRRRLGTGRHLPGAGAPPLTDEQVLAAWAELVDSAWDLGIPPDEARTPRH
                     AARRLAEDARLDADATAAAGRVALATERVMYARESQAPQQLGGDVRTTREALLVRATRR
                     RRLRALLLPASAVRLWWRAQDRAAARRERTAVRVAALRAAVTRPLRRKPERDERDRPGG
                     PDRRDG"
     gene            complement(3259..3636)
                     /locus_tag="KSE_RS10510"
                     /old_locus_tag="KSE_21360"
     CDS             complement(3259..3636)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135277.1"
                     /locus_tag="KSE_RS10510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21360"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_014135277.1"
                     /transl_table=11
                     /translation="MPLSEHEQRLLEQMERALYAEDPKFASALEGTGLHTYTRRRVYLA
                     VAGFVAGIALLMGGLVAQVIWVSVVGFLVMLGCAVLAVTAWRRGPAGHGPRQAAAPRRK
                     TGVVDRMEQRWQRRRDEQSGL"
     misc_feature    3740..3753
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     misc_feature    3747..3760
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.11"
                     /tool="antismash"
     gene            complement(3869..4621)
                     /locus_tag="KSE_RS10515"
                     /old_locus_tag="KSE_21370"
     CDS             complement(3869..4621)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327987.1"
                     /locus_tag="KSE_RS10515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21370"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_033258106.1"
                     /transl_table=11
                     /translation="MYPTRPRSALRTAVVWEVVRAALERRSAELGRPVLEVVDTGGGTG
                     NFAVPVARLGHRVTVVDPSPDALFALERRAAEAGVTELVRAVQGDAQTLPELVPAGSVD
                     AVLCHGVLEVVDDPAEALGNLVGTLGKGGLVSLLAANRNGAVLARAVAGQFTEARTALD
                     AADGRWGPGDPMPRRFTGEQLDALTADAGLKVTSVHGIRVFADLVPGVLVDTEPGALDA
                     LLKLELAAAEQPAFHAVATQLHLLAEAH"
     gene            complement(4773..5258)
                     /locus_tag="KSE_RS10520"
                     /old_locus_tag="KSE_21380"
     CDS             complement(4773..5258)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135279.1"
                     /locus_tag="KSE_RS10520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21380"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_014135279.1"
                     /transl_table=11
                     /translation="MTISRPEPVARPAVDQPTLPATRGADVHPVLRRGSAPPAALELLR
                     HAHRTLVYARGRQDPLERYATAHLAALRATAAVLAVRGRPVRGPRRRQAIRPAWELLPE
                     VAPELAEWAAYFAAGARRRAAAEAGITGAAGERDADDLIRNTALYLRIVERILALHP"
     misc_feature    complement(5405..5420)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            5742..6350
                     /locus_tag="KSE_RS10525"
                     /old_locus_tag="KSE_21390"
     CDS             5742..6350
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135280.1"
                     /locus_tag="KSE_RS10525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21390"
                     /product="DUF4126 domain-containing protein"
                     /protein_id="WP_014135280.1"
                     /transl_table=11
                     /translation="MGAVPLIFTSGWASGVNAYAVVLLLGLFGRFGGAETVPPVLGRTD
                     VLVAAGVLFLCEAVLDKIPYVDSAWDAVHTFVRPVAGATVGALLAAHDPGSLGEVAAGA
                     VGGTTALLSHGVKAGLRMAVNTSPEPASNILVSLAEDLSVAGLVTLALFHPWLAASAAA
                     VLLALGLLLAWFAVSRIRRFWLRRKERRARRRTGAAAPA"
     gene            6641..8029
                     /locus_tag="KSE_RS10530"
                     /old_locus_tag="KSE_21400"
     CDS             6641..8029
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141981.1"
                     /locus_tag="KSE_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21400"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_014135281.1"
                     /transl_table=11
                     /translation="MARIIVVGAGMGGLAAASRLGTLGHRVTVLEAAGTYGGQLGAYRR
                     EGFGFDTGPGLLALPAVYRDLALKTGREPLERLIGLRPVDPESRHLFPDGTELLLPNAS
                     RGGVGQALDAAFGAGAGARWGELLNRGRAVWEATRRPLLEEPRPAVDPADPYPVPPRRG
                     LSRLLPRGRHTLGDVARELGGGPGPAALLGEYALRYGLDPLGAPASATVLPYMEQSFGV
                     WYVDGGLRALADAVFARCGERGVEFRFDTPVRALERDGERVVGVRTDEGVLAADAVLSA
                     VPGLGAAEPAAPAPGRFTVLLALDGARPAGTAHRTVVHAADGAAEARAVFADGVLPDRP
                     TVQVLRPDDPSLVPGPDAEAAVLTVTVPARLALSAAEQDAYAGELLAHLAAAGLDLRPR
                     LRWRETRLTASVPPPSLAGGHLAQANRPGPEGLYLIGAHAHPGGGLARVGMSASITAGL
                     LGPA"
     gene            complement(8037..8753)
                     /locus_tag="KSE_RS38300"
                     /old_locus_tag="KSE_21410"
     CDS             complement(8037..8753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS38300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_21410"
                     /product="hypothetical protein"
                     /protein_id="WP_014135282.1"
                     /transl_table=11
                     /translation="MSVGYLLLYGALALVGLWLTAELLLQHRAALHWRALALAGFLGVV
                     AGMRMSSLPVIAAGAAGFGLGQLMVTGSVRRGRPVGWSLRRADGRLPGPLAKVPLLAAA
                     TGGAAAAAVEPEPVEPVGEVGPVEDESAPPFAEQPFAYEEFQQLDAGVYAEEQPAYQVP
                     QQPQYGYAQQDHGYQQQQQHYAQPQLQLIGYDQYGQPVYQDPYTQQQYQQPYVPQQQQP
                     QPQPQQDQNWYYQQQY"
     gene            complement(8915..9829)
                     /gene="metF"
                     /locus_tag="KSE_RS10540"
                     /old_locus_tag="KSE_21420"
     CDS             complement(8915..9829)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135283.1"
                     /locus_tag="KSE_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21420"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_014135283.1"
                     /transl_table=11
                     /translation="MALGIPSTRSDRAQTVRDLLAAGDRSFSFEFMPPRGEVGERKLWD
                     AIRRVESLEPNFVCMTYGAGGSSRGRTVDLVGRIATETTLTPVAHLTAVDHSTAELRNI
                     IGQYADQNVRNVLAVRGDPPGDPMGEWVRHPEGVTYAAELVELIKGIGDFCVGVAAFPQ
                     MHPRSVSWDEDIRHFVAKCRAGADYAITQMFFEVEDYLRLRDRVAAAGCETPIIPEIMP
                     VTNIRQLVRFPQLSGSDFPPEFRRRLEAAADDPAAVRAVGLEHATTMAERLLAEGAPGL
                     HFITLNHSTSTLEIYQNLGLHTR"
     misc_feature    9974..9988
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            10001..11107
                     /locus_tag="KSE_RS10545"
                     /old_locus_tag="KSE_21430"
     CDS             10001..11107
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135284.1"
                     /locus_tag="KSE_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21430"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_014135284.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-44, bitscore:
                     151.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSIRLPRNPVDAEDVRERVNRTLGEFMAERTALLSGISDQLGP
                     VSDALRDFLLDGGKRLRPAFCYWGWRAAGGGPDEPGIERAAAALELLQASALVHDDLMD
                     RSDTRRGLPAVHRRFENLHRAGGWRGDREQYGASAAVLLGDLLLIWCDELFQCSGLPTG
                     AVSSAKPVFDLMRTEVMLGQYLDVLEPVAGDSTDADALDRARTVLHYKSAKYTIERPLQ
                     VGALLAGAGPDLVDALGGFGLPLGEAFQLRDDLLGVFGDPAVTGKPAGDDLREGKRTLL
                     VAHAMRGLSPADAAHLDTRLGAPDLDAGQIAELRDLITLSGAPSTVEDRIEALLAEALA
                     ALAAAPVADGPTREVLRALADAATVRKY"
     gene            complement(11136..11795)
                     /locus_tag="KSE_RS10550"
                     /old_locus_tag="KSE_21440"
     CDS             complement(11136..11795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135285.1"
                     /locus_tag="KSE_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21440"
                     /product="VanZ family protein"
                     /protein_id="WP_033258108.1"
                     /transl_table=11
                     /translation="MDSLVPARRTRRFVLFVPVLLGAAVLAFVAQRPLGRRAGWDGWVG
                     TVNGVVFLAAVALPVAAAAVWWLARRRRVAGAGPGWARRSALADVGMVYGTLPWVWMIL
                     LPGVDPGGPRRRVNLVPLHDLAEVVAAGPPATAVAQIGGNLLVFAAFGFLAPLRFAALA
                     SGWRVLALGSAGSVLVETAQYVLRLDRVSSVDDVLLNAGGAALAALASRRWWRRTA"
     gene            complement(12065..12712)
                     /gene="thiE"
                     /locus_tag="KSE_RS10555"
                     /old_locus_tag="KSE_21450"
     CDS             complement(12065..12712)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135286.1"
                     /locus_tag="KSE_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21450"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_014135286.1"
                     /transl_table=11
                     /translation="MTAAPTARQRLADARLYLCTDARREQGDLPEFLDAVLGAGVDVVQ
                     LRDKGLEARQELEHLEVFADAARRHGKLLAVNDRADVAYGARPDVLHLGQDDLPVAVAR
                     RILGDDVLIGRSCHAESEVDTALTEPGVDYFCTGPVWPTPTKPGRPAPGLDLVRYAAAR
                     RPERPWFAIGGIDQDNLQQVLDAGATRIVVVRALTAAEDPAAAAAALAARLR"
     gene            complement(12709..13074)
                     /locus_tag="KSE_RS10560"
                     /old_locus_tag="KSE_21460"
     CDS             complement(12709..13074)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606129.1"
                     /locus_tag="KSE_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21460"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_014135287.1"
                     /transl_table=11
                     /translation="MSEIDPKIDALVPAWLYLPDISERWGVVITEVRDMVRNRSLLAVR
                     RGPNKSLQVPADFIEDDGPVKHLVSTLTVLRDSGFSDQEILEWMFTEDDSLPGSPIQAL
                     RENRGTEVKRRAQALAL"
     gene            complement(13092..14297)
                     /locus_tag="KSE_RS10565"
                     /old_locus_tag="KSE_21470"
     CDS             complement(13092..14297)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135288.1"
                     /locus_tag="KSE_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21470"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_014135288.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.5e-56, bitscore:
                     189.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAVAELSGTDRVVVVGAGMAGAQTALNLRQGGWHGPLALVGAEL
                     HLPYDRPPLSKDVLLGKADATAFEIDWHHLGVDLLTGRRATGLADGVLHTDRGELPYDA
                     LVIATGAEARTLPGLPGARTLRTVDDAHALRAALTPGRRIVLVGAGWIGAETATVAREL
                     GCHVTVVEAAAAPLAGALPAELGALMADWYAAAGVDLRCGTAVAGAADGGVLLTDGTHL
                     PADEVVVGIGGRPATDWLRGGPLALDPDGTVPVDDRLRTALPGVLAAGDCASYPSARAG
                     ARLAVQHWDHALHSGAAAAAALLGTLDGPYDPVPYFWSEQFGRMVQYAGRHAGADHLLW
                     RGSPSGPGWTVLWLRDGALTALLAVDRPRDLAQGRRLIERGTPVDPARAADPAVQLKAA
                     AR"
     regulatory      14389..14502
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(14458..14471)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            14470..15669
                     /gene="thiO"
                     /locus_tag="KSE_RS10570"
                     /old_locus_tag="KSE_21480"
     CDS             14470..15669
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015032971.1"
                     /locus_tag="KSE_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21480"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_148283084.1"
                     /sec_met_domain="DAO (E-value: 1.4e-64, bitscore: 217.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAKGASAAVAAFHAPGAGHAPDVLVVGGGIIGLGVAWRAAQRGL
                     AVAVADPDPGGGAARVAAGMLAPVTELQYGEEPLLRLGMASNERYAAFAAELTELTGLD
                     TGYRATGTLAVALDSDDREELRELHAFHGRLGLASTWLTGRECRRLEPMLAPGVRGGLH
                     VADDHQVDGRRLAAALVAACALAGVVFHRAEAVELLVEDGRAAGVRLSTGERVAAGRTV
                     LAAGSRSHLLPGLPDGVLPAVRPVKGQVLRLRMPTAHGPFLSRNVRAVVRGQHLYLVPR
                     ADGELVVGATTEELGHDTTVTAGGVYELLRDAHELVPGITELPLVETGAGLRPGSPDNA
                     PLLGPTALADLAAATGHYRNGVLLTPVTADLLADYLATGELPPLASDFTPDRFAPKVPA
                     "
     gene            15666..15875
                     /gene="thiS"
                     /locus_tag="KSE_RS10575"
                     /old_locus_tag="KSE_21490"
     CDS             15666..15875
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135290.1"
                     /locus_tag="KSE_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21490"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_014135290.1"
                     /transl_table=11
                     /translation="MNTIALTVNGEPRTLPAATTLDVVVAEVSAANTGVAAAVNEAVVP
                     RSSWPATALGEGDRVEILTAVQGG"
     gene            15879..16670
                     /locus_tag="KSE_RS10580"
                     /old_locus_tag="KSE_21500"
     CDS             15879..16670
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135291.1"
                     /locus_tag="KSE_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21500"
                     /product="thiazole synthase"
                     /protein_id="WP_014135291.1"
                     /transl_table=11
                     /translation="MADDELVIAGTSFGSRLIMGTGGAPSLEVLEQALRESGTELTTVA
                     MRRVNTATQGSVLEVLSRNGIRVLPNTAGCYTAGEAVLTARLAREALGTDWVKLEVIAD
                     ERTLLPDPIELLDAAETLVDDGFTVLPYTNDDPVLARKLEDVGCAAIMPLGSPIGSGLG
                     IRNPHNFQLIVEAANVPVVLDAGAGTASDVALAMELGCSAVMLASAVTRAQDPVLMAGA
                     MRRAVEAGRLAHRAGRIPRRYYAEASSPTAGLADTRERPAF"
     misc_feature    complement(16705..16719)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.61"
                     /tool="antismash"
     gene            16788..17102
                     /locus_tag="KSE_RS10585"
                     /old_locus_tag="KSE_21510"
     CDS             16788..17102
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KSE_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KSE_21510"
                     /product="hypothetical protein"
                     /protein_id="WP_014135292.1"
                     /transl_table=11
                     /translation="MTGADGHDGHGADGPGAGARRTNVPGAVLTCGPVVLFDGWLLTVG
                     VPLVAVPMFLVLLGALFGAATGRPNASASVRLYRAGVGALVTNLLLVLVLLFLLWRSEP
                     "
     gene            17185..18921
                     /gene="pknB"
                     /locus_tag="KSE_RS10590"
                     /old_locus_tag="KSE_21520"
     CDS             17185..18921
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF033483.0"
                     /locus_tag="KSE_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21520"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_051055172.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-49, bitscore:
                     167.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDDPLYGALLDGRYRVEQRIAVGGMSTVYRGTDTRLDRAVALK
                     VMHPALAADGEFTARFIREAKAVARLAHPNVVNVLDQGADPRGVFMAMEYVPGRTLRDL
                     LRDRGALSVRAALDVLEPVLAALGTAHRAGLVHRDVKPENVLITDTGLVKVADFGLVRV
                     LAGTDSAATSATGTGQLLGTVSYLAPEQIRQEDTDQRVDVYAAGILLYEMLTGTRPHTG
                     EHAAQVMYRHLHEDVPAPSRTAPAVGPELDAIVAAATARDPEARPWDAVELLAAVQRAR
                     RSLPPARLDAEPPASTRPTPVHNPGEATAVIETAHPMDRTSVLEVPPELLPPVRPAVND
                     DPPRGLPGRARRSGYGRRPLIWSAALVALLLVVGGITYALSSAVYATVPSVLGQSREQA
                     AATLDKQGLHGAFTEQYSESVQAGQVISTDPGVGAKVRKSDSVKVLLSRGPERLQVPDV
                     TGRPLADARKALGDARLTAGTSGEEFSDTVPKGSVISTAPAAGSSLAPNAPVALTVSKG
                     MHLVPDVGGLSKEDASAALTAAGFVPQVTGLLPLGKVTGQSPAAGTPARQGSTVTIAVS
                     LF"
     gene            complement(18947..19576)
                     /locus_tag="KSE_RS10595"
                     /old_locus_tag="KSE_21530"
     CDS             complement(18947..19576)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135294.1"
                     /locus_tag="KSE_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21530"
                     /product="sulfite oxidase-like oxidoreductase"
                     /protein_id="WP_014135294.1"
                     /transl_table=11
                     /translation="MGQQEPEQQPSTDPRLPPGQRPQRGWPVLHYGPVPRFKPQSWDFQ
                     VFGATADAEKASWDFAAFHALPKTTVRGDFHCVTKFSMLGNEWAGVAAATVLDLVPPDP
                     GVTHVMVWAEYGYSANLRLADFADPATVFATHHDGRPLTLEHGFPVRLVVPHLYAWKGP
                     KWVRAVEYMRADRRGFWEERGYHNLADPWREQRYSYQELPGDGPLR"
     misc_feature    complement(19793..19807)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 13.76"
                     /tool="antismash"
     gene            19876..20355
                     /gene="bfr"
                     /locus_tag="KSE_RS10600"
                     /old_locus_tag="KSE_21540"
     CDS             19876..20355
                     /EC_number="1.16.3.1"
                     /GO_function="GO:0004322 - ferroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /GO_process="GO:0006879 - intracellular iron ion
                     homeostasis [Evidence IEA]"
                     /GO_process="GO:0006880 - intracellular sequestering of
                     iron ion [Evidence IEA]"
                     /codon_start=1
                     /gene="bfr"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478270.1"
                     /locus_tag="KSE_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21540"
                     /product="bacterioferritin"
                     /protein_id="WP_014135295.1"
                     /transl_table=11
                     /translation="MQGDPEVIEFLNEQLTAELTAINQYFLHAKMQENFGWTKLAKYTR
                     HESFDEMKHAEVLTDRILFLDGLPNYQRLFHVRIGQTVKEMFEADRQVEVEAIDRLKRG
                     IVVMRAKNDITSANIFESILADEEHHIDYLDTQLELLDKLGEALYIAQLIEQPES"
     gene            complement(20386..20640)
                     /locus_tag="KSE_RS10605"
                     /old_locus_tag="KSE_21550"
     CDS             complement(20386..20640)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135296.1"
                     /locus_tag="KSE_RS10605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KSE_21550"
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="WP_014135296.1"
                     /sec_met_domain="Fer2_BFD (E-value: 4.4e-13, bitscore:
                     48.2, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVCMCHAVTEAQVKQKIDEGANTPRQIAQGCKAGTDCGSCVRRI
                     QALLGEHGARPCPTARLAERLGLADPAAATAAVTAPQAA"
     misc_feature    complement(20668..20686)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(20800..20814)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.35"
                     /tool="antismash"
     misc_feature    20911..20923
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
ORIGIN
        1 gacctgcgcc gggtgcactg gcggtccacc gcccggtacg gcgagctgat ggtccggcgc
       61 gaggagcagc cgctgcaggc ccgcgcgacc gtgctgctgg acacccggga gaccgcgcac
      121 cgcggctccg ggccggcctc ctcgttcgag tgggcggtgt cctgcgccgc ctcggtcgcg
      181 gtcgacctgg tgcagcgcgg ctaccgcacc cggctgctca ccgacaccgg cttcgcggtg
      241 cccgcgacgg gcgccggcgg tggcggcacc accgccgccg agtcggtcgg cctgctgctg
      301 gacgcgctgg ccgtggtcga gcactccgac ggcggcacgc tggcccgggc cgaggaggtg
      361 ctccggctcg gcggcgaggg cctgctggtc gcggtggtcg gcgagctgga cgaggagcag
      421 gccgagcggc tggcccggct gcgccgccgc accggcggcg ccgtcgtcct gctgctggac
      481 accggcacct gggccggcct gcggcacggg ctgccggacg gcgccggcga gcgggccgcg
      541 gcccgggtca cccggctgcg cgagtccggc tggaccgtgc tgccggtgcg ggccggcgac
      601 tcgctgcccg cgctgtggcg gaccgcggac cgcacccaga acaccaccgt tccctaccga
      661 gacgaggtcg gcgcgtgacc acccgggcca agttgacgct ctgcgcggcc ctggccaccg
      721 ccctggcggc gctgtgcctg tccccgctgt tccaggactc cttcgcgctg gccccgcacg
      781 gcctgctgat ggttgccgtc gcggccggcg ccggcgccgg cctgcgcgcg ctgccgctgc
      841 cgcgggccct ggtgccgccg ctgcagctcc tcgtggtgct gtacgtgctg ctgctgacca
      901 ccgtgcggtc cgcgatggcc gccggcctgc tgcccggccc gggcgcgctg gacgcggtct
      961 ccacgctgct ctcccagggc ggcagcgacg tccaggagta cgcgatcccg gccccggcca
     1021 ccgacggcct gcggctgatc gtggtcggct cggtcgccct gatcgccgtg ctggtcgacg
     1081 ccctggcggt cacctaccgc cgggccgccg ccgcgggcct gccgctgctg gccctgtact
     1141 cggtggccgg cggcctggtc gactcgccgg gcggcatgtg gctgtggttc ctgttcggct
     1201 cggccggcta cctggccctg ctgtacgtcg agggccagga ccggctgacc cgctggggcc
     1261 gggtcttcca cggcaccggc cgctccgccg tgacgctctc caacggcggc cgccggatcg
     1321 gcgtgatcgc gctggccgcc gccgtcctgc tgccggtgtt cgtgcccgcg gtcggccccg
     1381 gcctgttcgg cgggcacggc tcgggcgacg gcaccgggac gggcggcggg aacggcacca
     1441 tggaccagcg ctcgctcaac ctggtcgtcg cgctcaccgc caacctgcgc tccaacgacg
     1501 acacccagct gctgtccttc tccaccgact cccccgaccc cgaccagctc tacctgcgga
     1561 tcgccgcgct cagcgagttc aacggccagg agtggctgcc cggcccgcag gacccgcagc
     1621 cgatgcccac cacggtgccc gcgcccgagg gcctctcgcc gaacctgccg acctcctcgg
     1681 tccgcaccaa catcaccgtc gcggaccagc tcagcaccgc ctggctgccg atgccgtacc
     1741 cgatgtcctg ggtgcagctg ccgagcacct cggactggcg cttcgacccg accgggcgca
     1801 ccgtcagcgg cgtcaacggc cagaagagca agggcctgac gtactccgtc ggctcggtcg
     1861 cggtgggcgc caccgccgcc cagctgcgcg ccgccggccc gacccccgag accgtcggca
     1921 agcgctacct gggcctgccc gcgaacctgc cggccgtggt cggcgagacc gccaggaccg
     1981 tcaccaaggg caagaccacc ccgtacgacc aggccgtcgc cctgcagcag tacttcaccg
     2041 gcgggggctt cacctacaac accaagatcg acgcccgcac cgggccggac gccatcgcca
     2101 agttcctcca ggacaaggag ggcttctgcg tgcacttcgc cgccaccatg gcggcgatgt
     2161 cccgctcgct gggcatcccg gcccgggtcg cgatcggctt caccccgggc agcggcggcg
     2221 gcagcagccg ggtggtgcgc agctccaact accacgcctg gcccgagctg tacttcaacg
     2281 gctacggctg gatgcgcttc gaaccgaccc cgaaccgggg cagcaccccg ctgtactccg
     2341 tccagcaggc cgcgcccagc accgccccca gcaccgcgcc gagcagcgcc gcgccgagcg
     2401 agcagccctc ggcccagccg tcctcctcca gcagctgccc gccgcagcag cacaagctgg
     2461 gcgactgcgc cgacgagacc gcgctggccg agcggaagac gaccaccacc gcctggtggc
     2521 ggtcctggac ggtgctggcc ggcgtcctgg gcggactgct ggtggcgggc ctgctggcct
     2581 tcccgatgct gtggcgcacc aggctgcgcc gccgccgcct cggcaccggc cgccacctgc
     2641 ccggcgcggg cgccccgccg ctcaccgacg agcaggtgct ggccgcctgg gccgaactcg
     2701 tcgactccgc gtgggacctc ggcatcccgc ccgacgaggc ccgcaccccg cggcacgccg
     2761 cccgccggct cgccgaggac gcgcggctcg acgccgacgc gacggccgcc gccggccggg
     2821 tcgcgctcgc caccgagcgg gtgatgtacg cccgcgagtc gcaggcgccg cagcagctgg
     2881 gcggcgacgt ccgcaccacc cgcgaggcgc tgctggtccg ggccacccgc cggcgccggc
     2941 tgcgcgccct gctgctgccg gcctccgcgg tccggctgtg gtggcgcgcc caggaccggg
     3001 ccgcggcccg ccgggagcgc accgccgtac gggtggcggc gctccgcgcg gcggtcaccc
     3061 ggccgttgcg gcgcaagccc gagcgggacg agcgggaccg gccgggcgga ccggaccggc
     3121 gggacggcta gcggcagcgg cggcagccac gggcgcggcg gcggccgcga caaaagatcc
     3181 gcccggcgag ggtctccctc gccgggcgga tcgcgtctgg tgggccgctc gccccgcagg
     3241 gtgccgtccc ggtcggtgct acaggccgct ctgctcgtcg cggcggcgct gccagcgctg
     3301 ttccattcga tcgacgacac cggtcttccg gcgtggcgct gccgcctgcc gtgggccgtg
     3361 tccggccggg ccgcgacgcc acgcggtgac cgcgaggacg gcgcagccga gcatcaccag
     3421 gaacccgacc acgctgaccc agatgacctg ggcgaccagg ccccccatga gcagcgcgat
     3481 gcccgccacg aaacccgcca cggccaggta gacccgccga cgcgtgtagg tgtgcaggcc
     3541 ggttccctcg agcgctgacg cgaacttggg atcttcggcg tacagcgctc gctccatctg
     3601 ctcgagcagt cgctgctcgt gctccgagag cggcacggag tcctcctact cgtcggtcgc
     3661 ggggcgaccg gtccgccacc cctggctcgg gcctgtgtgg tccatatgcc ccaccggtct
     3721 ggccgtcatg cttaccggct ttacccagat catacggtcc acggccgcgg ttcggcgtgg
     3781 tcaatcaggc gtggctcggg ccgccgcgtc ggcggcccgc acccctgcaa cgagcggggg
     3841 gcccgcttgg tgcccccgcc gggaggattc agtgggcctc ggccagcagg tggagctggg
     3901 tggcgacggc gtggaaggcg ggctgctcgg cggcggcgag ctccagcttg agcagggcgt
     3961 cgagggcgcc cggctcggtg tcgaccagga cgccggggac gaggtcggcg aagacccgga
     4021 tgccgtgcac ggaggtgacc ttcagcccgg cgtcggcggt cagcgcgtcc agctgctcgc
     4081 cggtgaagcg gcggggcatc gggtcgccgg ggccccagcg gccgtcggcg gcgtccagcg
     4141 cggtgcgggc ctcggtgaac tggccggcca ccgcgcgggc cagcacggcg ccgttgcggt
     4201 tggcggcgag caggctgacc agcccgccct tgccgagggt gccgaccagg ttgccgagcg
     4261 cctcggccgg gtcgtcgacg acctccagga cgccgtggca gagcaccgcg tcgaccgatc
     4321 cggccgggac cagctcgggc agcgtctggg cgtcgccctg gacggcccgg accagctcgg
     4381 tgacaccggc ctcggcggcc cggcgctcca gcgcgaacag cgcgtccggg ctggggtcga
     4441 ccacggtgac ccggtggccc agccgggcca ccggcacggc gaagttgccg gtgccgccgc
     4501 cggtgtcgac gacctccagc accggccgtc cgagctcggc cgagcgccgc tccagcgccg
     4561 cccgcaccac ctcccacacc acggcggtac gcaacgcact gcggggacga gtcggataca
     4621 aggcggcacc cctcttggca ggtcttccac ggcgggacac ctccacctta tccgccgggg
     4681 cggggcggcc ggggtgcggc cgaggcgcgg ccgaggtgcg gctgaggtgc ggctgaggtg
     4741 cggcgcagca ccgggcggct cggcggcggg gctcaggggt gcagggccag gatccgctcc
     4801 acgatccgca ggtacagggc ggtgttgcgg atcaggtcgt ccgcgtcgcg ctcgccggcg
     4861 gcgccggtga tgccggcctc ggcggcggcc cggcggcgcg cgccggccgc gaagtaggcg
     4921 gcccactcgg cgagttcggg agcgacctcg ggcagcagct cccaggccgg gcggatcgcc
     4981 tggcggcggc gcgggccgcg caccgggcgg ccgcgaacgg ccagcacggc ggcggtggcg
     5041 cgcagcgcgg cgaggtgggc ggtggcgtac cgctccagcg ggtcctgtcg gccgcgggcg
     5101 tacaccaggg tgcggtgcgc gtggcggagc agttcgagcg ccgcgggcgg ggccgagccc
     5161 cggcgcagca ccgggtggac gtcggcgccg cgggtggccg gcagggtggg ttgatcgacg
     5221 gcagggcggg cgacaggctc aggacgactg atggtcatgg gtctcccccg ttcactccgg
     5281 accttgcccg gaccggtcgg tccgcgcatg catccatcgt gaacgggggg tctgacaact
     5341 cggggtcccc caccccgcgg ggccccccga ccccgttccg tcgtccccca cggccgtccc
     5401 gggttccccc ccagggggag ggggtcgggc tccgccgccc cgtgtcggcg gtgcccggcc
     5461 ccctcgctcc ggccgttggt tcgcgttccg gacgcggcat ggtccgccga atccccccgg
     5521 gttcgacgac cgccccggaa cgctccgggt ggctccgccc ggcggcggcc ttcccggtgc
     5581 gcactactct gcccgccggg cgggggcgcc gggtatccgc ccgggtactc aaccggtggt
     5641 ctgagtacgc gtactcaggc ccgccggagg tcggccgggc cgggtacggt ggccgcgtcc
     5701 cgtccgaggt ccgggctggg ggcgtacggg agggggccgc cgtgggggcc gttccactga
     5761 tcttcaccag cggctgggcg agcggcgtca acgcgtacgc cgtggtcctg ctgctgggcc
     5821 tgttcggccg cttcggcggg gcggagaccg tgccgccggt gctggggcgc acggacgtgc
     5881 tggtcgccgc cggggtgctg ttcctgtgcg aggcggtcct cgacaagatc ccgtacgtgg
     5941 acagcgcctg ggacgcggtg cacaccttcg tccgcccggt cgccggggcg accgtcggcg
     6001 ccctgctcgc cgcgcacgac cccggctcgc tcggcgaggt cgcggccggg gcggtcggcg
     6061 gcacgaccgc cctgctcagc cacggcgtca aggcgggcct gcggatggcg gtgaacacct
     6121 cgcccgaacc ggcctccaac atcctggtca gcctcgccga ggacctctcc gtcgcgggcc
     6181 tggtcaccct ggcgctcttc cacccctggc tggccgcctc cgccgccgcc gtcctgctgg
     6241 ccctcggcct gctgctcgcc tggttcgcgg tctcccggat ccgccgcttc tggctccgcc
     6301 gcaaggagcg ccgcgcccgg cgccgcacgg gggcggccgc cccggcctga gcacgccgcg
     6361 cggggacgcg gcgcagcggc cgggcccgga agtgccgacc gcgacggccc ggctccgccg
     6421 ggggcggcac cggaccggac ccggacgcca ggccgccacc gaccgcccga cgcggggcgc
     6481 cgcgccgcca ggcaggctca agcgcgcgcc cagcgcggca gaggcacgac ggcgcccgcc
     6541 gggggcgccg accgcgacgg cccggctccg ccgggggcgg ggcgggaggg gcggggcgcg
     6601 gcgtggggcc ggggtgcggg ggcgcatagg atcttctgcc atggctcgga tcatcgtcgt
     6661 cggcgcaggc atgggcggtc tggcggccgc ctcccggttg ggcacgctcg ggcaccgggt
     6721 gacggtgctg gaggcggccg gcacgtacgg ggggcagctg ggggcgtacc ggcgggaggg
     6781 gttcgggttc gacaccgggc cggggctgct ggcgctgccc gccgtgtacc gggacctggc
     6841 gctgaagacc gggcgggagc cgttggagcg gctgatcggg ctgcggccgg tcgatccgga
     6901 gagccggcac ctgttcccgg acgggacgga gctgctgctg ccgaacgcct cgcggggcgg
     6961 ggtcgggcag gcgctggacg ccgcgttcgg ggcgggcgcc ggcgcgcgct ggggcgagct
     7021 gctgaaccgg ggccgcgcgg tgtgggaggc gacccggcgg ccgctgctgg aggagccgcg
     7081 gccggccgtc gacccggccg acccgtaccc ggtgccgccg cgccgcggcc tgtcccggct
     7141 gctgccgcgc gggcggcaca ccctgggcga cgtggcccgc gagctgggcg gcgggcccgg
     7201 tccggcggcg ctgctgggcg agtacgcgct gcgctacggc ctggacccgc tgggcgcgcc
     7261 cgcctcggcg acggtgctgc cgtacatgga gcagtcgttc ggcgtctggt acgtggacgg
     7321 cggcctgcgg gcgctcgccg acgcggtgtt cgcgcgctgc ggcgagcgcg gcgtggagtt
     7381 ccgcttcgac accccggtgc gggccctgga gcgggacggc gagcgggtgg tgggcgtccg
     7441 caccgacgag ggcgtgctgg cggcggacgc ggtgctgtcc gccgtccccg ggctgggcgc
     7501 ggccgagccc gccgcgcccg cgccgggccg gttcaccgtg ctgctcgcgc tggacggcgc
     7561 ccgtccggcg ggcaccgcgc accgcaccgt cgtgcacgcg gcggacggcg cggccgaggc
     7621 ccgcgcggtc ttcgccgacg gcgtgctgcc ggaccgcccc accgtgcagg tgctgcgtcc
     7681 ggacgacccg tcgctcgtcc ccggaccgga cgcggaggcc gccgtgctga ccgtcaccgt
     7741 gcccgcccgg ctcgccctca gcgccgccga acaggacgcg tacgccgggg agttgctcgc
     7801 ccacctggcc gccgccggcc tcgacctgcg cccccggctg cgctggcggg agacccgact
     7861 gaccgcctcc gtcccgccgc cttcgctggc cggcggccac ctcgcccagg ccaaccggcc
     7921 cggccccgag ggcctctacc tgatcggcgc gcacgcccac ccgggcggcg ggctggcccg
     7981 ggtcgggatg tccgcctcga tcaccgccgg gctgctcggc ccggcctgac ggtgcgtcag
     8041 tactgctgct ggtagtacca gttctggtcc tgctggggct gcggctgggg ttgctgctgc
     8101 tgcgggacgt acggctgctg gtactgctgc tgggtgtacg ggtcctggta gaccggctgc
     8161 ccgtactggt cgtagccgat cagctgcaac tgcggctggg cgtagtgctg ttgctgctgc
     8221 tggtagccgt ggtcctgctg ggcgtagccg tactgcggct gctgcgggac ctggtaggcg
     8281 ggctgctcct cggcgtagac gcccgcgtcg agctgctgga actcctcgta ggcgaagggc
     8341 tgctccgcga acggcggcgc cgactcgtcc tcgaccggcc cgacctcgcc gaccggctcc
     8401 accggctccg gctccacggc ggcggcggcc gccccgccgg tggccgccgc cagcagcggg
     8461 accttcgcca gcgggccggg cagccggccg tccgcccggc gcagcgacca gcccaccggg
     8521 cggccgcgcc gcaccgagcc cgtcaccatc agctggccga gcccgaaccc ggcggcgccc
     8581 gccgctatca ccggcagcga ggacatccgc atcccggcca cgacgcccag gaaacccgcc
     8641 agcgcgagcg cccgccagtg cagcgcggcc cggtgctgga gcagcagttc ggcggtcagc
     8701 cagagcccga ccagggccag cgcgccatag aggagcaggt atccgacgct catccccgca
     8761 acctccagac gccaccatca ccgcgcggtt gcgggcgact gtacagcctc cgggcgaaca
     8821 ccaccgcatc ccggaccgga cctccccgag acccccgcac aagcctgccc ggacgggcag
     8881 ccgggggccg ggcgcgcggc tcggccggag cgggtcagcg ggtgtggagg cccaggttct
     8941 ggtagatctc cagcgtcgag gtcgagtggt tgagcgtgat gaagtgcagg ccgggggcgc
     9001 cctccgcgag gagccgctcg gccatcgtgg tggcgtgctc caggccgacc gcgcggaccg
     9061 cggccgggtc gtcggcggcg gcttcgaggc ggcggcggaa ctcgggcggg aagtcggagc
     9121 cggagagctg cgggaagcgc accagctggc ggatgttggt gaccggcatg atctccggga
     9181 tgatcggcgt ctcgcagccg gccgcggcga cccggtcgcg cagccggagg tagtcctcga
     9241 cctcgaagaa catctgggtg atcgcgtagt ccgcgccggc ccggcacttg gcgacgaagt
     9301 gccggatgtc ctcgtcccag ctgaccgagc gggggtgcat ctgcgggaac gcggcgacgc
     9361 cgacgcagaa gtcgccgatg cccttgatca gttcgaccag ctcggcggcg tacgtgacgc
     9421 cctcggggtg ccggacccac tcgcccatcg ggtcgccggg cgggtcgccg cgcacggcca
     9481 gcacgttgcg cacgttctgg tcggcgtact ggccgatgat gttgcgcagt tcggcggtcg
     9541 agtggtcgac cgcggtgagg tgggcgaccg gggtcagggt ggtctcggtg gcgatccggc
     9601 cgaccaggtc gacggtgcgg ccgcgcgagg agccgcccgc gccgtacgtc atgcagacga
     9661 agttcggctc cagcgactcg acccggcgga tcgcgtccca gagcttgcgc tcgccgactt
     9721 cgccgcgcgg cggcatgaac tcgaaggaga aggagcggtc gcctgccgcc agcaggtcgc
     9781 gcacggtctg cgcgcggtcg cttctggtgg agggaatgcc gagtgccatg caggcaggtt
     9841 agccgtcggc ggcgcgagcc ggacaaacct ggtccaacca ttgagacgcc gcttgagatt
     9901 ttcggccgtt cccgcccggg cggcccggcg ggcgggtgga acgggggacc cgaccgggcg
     9961 cgttaatctg actgtcagcc ccctcgatcc ggagtctcag gtgccctcct ccatccgcct
    10021 tccccgcaac cccgtcgacg cggaggacgt gcgcgagcgc gtgaaccgca cgctcggcga
    10081 gttcatggcc gagcggacgg ccctgctctc cgggatctcc gaccagctcg gaccggtctc
    10141 cgacgcgctg cgcgacttcc tgctggacgg cggcaagcgg ctgcgcccgg cgttctgcta
    10201 ctggggctgg cgggcggccg gcggcggccc ggacgagccc ggcatcgaac gggcggcggc
    10261 cgcgctggag ctgctgcagg ccagcgccct ggtgcacgac gacctgatgg accgcagcga
    10321 cacccgccgc ggcctgcccg ccgtccaccg ccgcttcgag aacctgcacc gggcgggcgg
    10381 ctggcgcggc gaccgcgagc agtacggggc gtccgccgcg gtactgctcg gcgacctgct
    10441 gctgatctgg tgcgacgagc tgttccagtg ctccgggctg ccgaccggcg cggtgtcctc
    10501 cgcgaagccg gtgttcgacc tgatgcgcac cgaggtgatg ctcggccagt acctggacgt
    10561 gctggagccc gtcgcgggcg actccaccga cgcggacgcg ctcgaccggg cccggacggt
    10621 gctgcactac aagtccgcga agtacaccat cgagcggccg ctgcaggtcg gcgcgctgct
    10681 cgcgggcgcc ggacccgacc tggtcgacgc cctcggcggc ttcggcctgc cgctcggcga
    10741 ggcgttccag ctccgcgacg acctgctcgg cgtcttcggc gacccggcgg tcaccggcaa
    10801 gccggccggc gacgacctcc gtgagggcaa gcgcaccctg ctcgtcgccc acgccatgcg
    10861 cggcctctcc cccgccgacg ccgcccacct cgacacccgg ctcggcgccc ccgacctgga
    10921 cgccgggcag atcgccgaac tccgcgacct gatcaccctc agcggcgccc cctccaccgt
    10981 cgaggaccgg atcgaggccc tgctcgccga ggccctcgcc gccctcgccg cggccccggt
    11041 cgccgacgga cccacccgcg aggtgctgcg ggcgctcgcg gacgccgcga cggtccgcaa
    11101 gtactgaccg gaagactgac cggaagaagg ccgcgtcagg ccgtccgccg ccaccagcgg
    11161 cgggaggcca gcgccgcgag ggcggcgccg ccggcgttca acaggacgtc gtcgaccgag
    11221 gagacccggt ccagccgcag cacgtactgg gcggtctcca ccagcaccga acccgccgag
    11281 cccagcgcca gcacccgcca ccccgaggcc agcgcggcga accgcagcgg ggcgaggaag
    11341 ccgaacgcgg cgaacaccag caggttgccg ccgatctgcg ccaccgcggt ggccggcggc
    11401 ccggccgcga ccacctcggc gaggtcgtgc agcggcacca ggttcacccg gcggcgcggg
    11461 ccgcccgggt cgacgcccgg cagcaggatc atccagaccc acggcagcgt cccgtacacc
    11521 atcccgacgt cggccagcgc cgaacgccgc gcccaccccg gccccgcacc ggccacccgg
    11581 cggcggcgcg ccagccacca caccgccgcg gccgccaccg gcagcgcgac ggcggccagg
    11641 aacacgacgc cgttgaccgt ccccacccag ccgtcccacc cggcgcgccg gcccagcggg
    11701 cgctgcgcga cgaaagcgag aacggccgcg ccgagcagca ccgggacgaa cagcacgaac
    11761 cgccgggtcc ggcgggcggg cacgagggaa tccatgcctg cacggagtac gcaccgcgcc
    11821 cccgcggttc ccggccgggg ggcggagccg ctcccgagcc gggcctgccc ggccgagggc
    11881 gcgaagcacg gaggccgacc gcgcgcaccg ccaggccccc ggccggggca ccgacctccc
    11941 cgcaccagga cccgcccgac tgcccttccg ccctcgcgcg cttccccgcg ccgcgcacgg
    12001 ggcgcggagc gcgggtgttc cggcgtgtcc tcgcgcgggc cggggcgccg cggggccgga
    12061 gggcctagcg gaggcgggcc gcgagggcgg cggccgcggc ggcggggtcc tcggcggcgg
    12121 tgagggcgcg gacgacgacg atgcgggtgg cgccggcgtc gaggacctgc tggaggttgt
    12181 cctggtcgat gccgccgatg gcgaaccagg ggcgttcggg ccgccgcgcc gcggcgtacc
    12241 ggaccaggtc gaggccgggg gcgggccggc cgggcttggt cggggtgggc cagaccgggc
    12301 cggtgcagaa gtagtcgacg ccgggttcgg tgagcgcggt gtcgacctcg ctctcggcgt
    12361 ggcaggagcg gccgatcagc acgtcgtcgc cgaggatgcg gcgggcgacg gcgaccggga
    12421 ggtcgtcctg gccgaggtgc agcacgtcgg ggcgggcccc gtacgcgacg tcggcgcggt
    12481 cgttgacggc gagcagcttg ccgtggcggc gggcggcgtc ggcgaagacc tccaggtgtt
    12541 ccagctcctg ccgggcttcc aggcccttgt cgcggagctg gacgacgtcg acgccggcgc
    12601 cgagcaccgc gtccaggaac tcgggcaggt cgccctgttc gcggcgggcg tcggtgcaga
    12661 ggtagagccg ggcgtcggcc aggcgctgcc gggcggtggg cgcggccgtc acagggccag
    12721 ggcctgggcg cggcgcttga cctcggtgcc gcggttctcg cgcagggcct ggatcgggct
    12781 gccgggcagc gagtcgtcct cggtgaacat ccactccagg atctcctggt cggagaagcc
    12841 ggagtcgcgc agcaccgtga gggtgctgac caggtgcttg accgggccgt cgtcctcgat
    12901 gaagtcggcg gggacctgga gggacttgtt gggtccccgg cggacggcca gcaggctgcg
    12961 gttgcgcacc atgtcgcgga cctcggtgat caccacgccc caccgctccg agatgtcggg
    13021 caggtacagc caggcgggga ccagggcgtc aatcttggga tcaatctcgc tcacggtccc
    13081 cagcctaggc gctaccgggc cgcggccttc aactggacgg ccgggtcggc ggcccgggcg
    13141 gggtcgaccg gggtgccgcg ttcgatcagc cggcggccct gggcgaggtc gcgcggccgg
    13201 tcgacggcga gcagcgcggt gagggcgccg tcgcgcagcc agagcaccgt ccagccgggt
    13261 ccggacgggg agccgcgcca cagcaggtgg tcggcgcccg cgtgccggcc ggcgtactgg
    13321 accatccggc cgaactgctc ggaccagaag tacgggacgg ggtcgtacgg gccgtcgagg
    13381 gtgccgagca gcgcggccgc ggcggcggcg ccggagtgca gggcgtggtc ccagtgctgg
    13441 acggcgagcc gggcgccggc ccgggcggac gggtaggagg cgcagtcgcc ggcggcgagg
    13501 acgccgggca gcgcggtgcg cagccggtcg tcgaccggga ccgtgccgtc ggggtcgagg
    13561 gcgagcgggc cgccgcgcag ccagtcggtg gcggggcggc cgccgatgcc gacgacgacc
    13621 tcgtcggcgg gcaggtgggt gccgtcggtg agcagcacgc cgccgtcggc ggcgcccgcg
    13681 acggcggtgc cgcagcgcag gtcgacgccg gcggcggcgt accagtcggc catcagggcg
    13741 ccgagttcgg cgggcagggc gccggccagc ggggcggcgg cggcttccac cacggtgacg
    13801 tggcagccga gttcgcgggc gacggtggcg gtctcggcgc cgatccagcc cgcgccgacc
    13861 agcacgatcc ggcggccggg ggtgagcgcg gcgcgcagcg cgtgggcgtc gtcgacggtg
    13921 cgcagggtgc gggcgccggg caggccgggg agggtgcggg cctcggcgcc ggtggcgatc
    13981 accagggcgt cgtacgggag ttcgccgcgg tcggtgtgca ggacgccgtc ggcgaggccg
    14041 gtggcgcggc ggccggtgag caggtcgacg ccgaggtggt gccagtcgat ctcgaaggcg
    14101 gtggcgtcgg ccttgccgag cagcacgtcc ttggagagcg ggggccggtc gtaggggagg
    14161 tggagttcgg cgccgaccag ggcgagcggg ccgtgccagc cgccctgccg caggttgagg
    14221 gcggtctggg cgcccgccat gcccgcgccg accacgacga cccggtccgt tccgctcagt
    14281 tcagccacgg cgtccaccct atcggggcgc ggtcggcgtc caccccgcgt acgcgccttc
    14341 tgggcggggt cggggcggcg ttatggtggg ggtggttcaa caacctacgt acgtcatcac
    14401 gggagcccgg cgcaccgggc tgagaggcgg gctgtggcgg cccgcgaccg tccgaacctg
    14461 atccgggtca tgccggcgaa gggagcatca gcggctgtgg cagctttcca cgcgcccggg
    14521 gcagggcacg cgcctgacgt gctggtggtc ggcgggggca tcatcgggct gggcgtcgcc
    14581 tggcgggcgg cgcagcgcgg cctggcggtc gcggtggccg acccggatcc gggcggcggc
    14641 gcggcccggg tcgcggcggg catgctcgcc ccggtcaccg aactgcagta cggcgaggag
    14701 ccgttgctgc ggctggggat ggcctcgaac gagcggtacg cggcgttcgc cgccgaactg
    14761 accgagctga ccggcctgga caccggctac cgggcgaccg gcacgctggc ggtcgcgctg
    14821 gactccgacg accgcgagga gctgcgcgag ctgcacgcct tccacggccg gctgggcctg
    14881 gcgtccacgt ggctgaccgg ccgggagtgc cgccggctgg agccgatgct ggcgccgggc
    14941 gtccggggcg gcctgcacgt cgccgacgac caccaggtgg acggccgccg gctggccgcc
    15001 gcgctggtcg cggcctgcgc gctggcgggc gtggtgttcc accgggcgga ggccgtcgag
    15061 ctgctggtcg aggacggccg ggcggcgggc gtccggctgt cgaccggcga gcgggtggcg
    15121 gcggggcgca cggtgctggc cgccggttcg cgcagccacc tgctgccggg cctgccggac
    15181 ggggtgctgc cggccgtccg cccggtgaag ggccaggtgc tgcggctgcg gatgccgacc
    15241 gcgcacgggc cgttcctgtc ccggaacgtg cgggcggtgg tgcgcgggca gcacctgtac
    15301 ctggtgccgc gggcggacgg cgagctggtg gtcggcgcga ccaccgagga gttggggcac
    15361 gacaccacgg tcaccgcggg cggcgtctac gagctgctcc gggacgcgca cgaactggtg
    15421 cccggcatca ccgagttgcc gctggtggag accggcgcgg ggctgcgccc cggctcgccc
    15481 gacaacgcgc cgctgctcgg cccgaccgcg ctggccgacc tggccgccgc gaccgggcac
    15541 taccgcaacg gcgtgctgct caccccggtc accgccgacc tgctcgccga ctacctggcc
    15601 accggcgaac tcccgccgct ggcaagcgac ttcacccctg accgcttcgc ccccaaggtc
    15661 cccgcatgaa caccatcgcc ctgaccgtca acggcgagcc gcgcaccctg cccgccgcca
    15721 ccacgctgga cgtggtggtc gccgaggtgt cggccgccaa caccggcgtc gcagccgccg
    15781 tcaacgaggc ggtggtgccg cgcagttcgt ggcccgccac cgcgctcggc gagggcgacc
    15841 gggtcgagat cctgaccgcc gtccaaggag gctgaaccat ggctgacgac gaactggtga
    15901 tcgccggcac gtccttcggc tcccggctga tcatgggcac cggcggcgcc cccagcctgg
    15961 aggtgctgga gcaggcgctg cgggagtccg gcaccgagct gaccacggtc gcgatgcgcc
    16021 gggtgaacac cgccacccag ggttcggtcc tggaggtgct gtcccgcaac ggcatccggg
    16081 tgctgccgaa cacggccggc tgctacacgg cgggcgaggc ggtgctgacc gcccggctgg
    16141 cccgcgaggc gctcggcacc gactgggtga agctggaggt gatcgccgac gagcggaccc
    16201 tgctgcccga cccgatcgaa ctgctggacg ccgccgagac gctggtcgac gacggcttca
    16261 ccgtgctgcc gtacaccaac gacgacccgg tgctggcccg caagctggag gacgtcggct
    16321 gcgcggcgat catgccgctg ggctcgccga tcggctccgg cctgggcatc cgcaacccgc
    16381 acaacttcca gctgatcgtg gaggccgcga acgtcccggt ggtgctggac gcgggcgcgg
    16441 gcaccgcgag cgacgtcgcg ctggcgatgg agctgggctg ctcggccgtc atgctggcgt
    16501 ccgccgtgac ccgcgcccag gacccggtgc tgatggccgg cgcgatgcgc cgggcggtcg
    16561 aggccggccg cctcgcccac cgggccggcc ggatcccccg ccgctactac gccgaggcgt
    16621 cctcccccac cgccggcctg gccgacaccc gcgaacgccc ggcgttctga cccgcccgcc
    16681 ccacccgccc ccgtgtcccg gttctggaac ggttcggccc gcgaccgcgc ccgggccggg
    16741 ggcggctgcc accatggcaa cgccgtacgg ggaaccaggg ggggctgatg acgggggcgg
    16801 acgggcacga cgggcacggg gcggacgggc ccggggcggg ggcgcgccgg acgaacgtgc
    16861 cgggcgcggt gctgacctgc gggccggtgg tgctgttcga cggctggctg ctgaccgtgg
    16921 gcgtgcccct cgtggcggtg ccgatgttcc tggtgctgct cggggcgctg ttcggcgcgg
    16981 ccaccgggcg cccgaacgcg tcggcctcgg tccggctgta ccgggcgggg gtgggcgccc
    17041 tggtcacgaa cctcctcctg gtgctcgtgc tgctgttcct gctctggcgc tccgagccgt
    17101 agcgcccccc tgccgaccga cctgtcgacc ggcccgccga cgggcccgct ccgacaccga
    17161 acccctagac tccctcgggt ggacatgacc ctcgacgatc ccctgtacgg cgcgctgctg
    17221 gacggccgct accgcgtcga gcagcggatc gcggtcggcg gcatgtcgac cgtctaccgg
    17281 ggcaccgaca cccggctgga ccgggccgtg gcgctgaagg tgatgcaccc ggcgctggcg
    17341 gcggacgggg agttcacggc gcgcttcatc cgggaggcga aggcggtggc ccggctcgcc
    17401 cacccgaacg tggtcaacgt gctggaccag ggcgccgatc cgcgcggcgt gttcatggcc
    17461 atggagtacg tgcccggccg caccctgcgc gacctgctgc gcgaccgcgg cgcgctctcg
    17521 gtgcgggccg cgctggacgt gctggagccg gtgctggcgg cgctcggcac cgcgcaccgg
    17581 gccgggctgg tgcaccggga cgtcaagccg gagaacgtgc tgatcaccga caccggcctg
    17641 gtgaaggtcg ccgacttcgg cctggtccgg gtgctggcgg gcaccgactc ggcggccacc
    17701 tcggccaccg ggaccggcca actgctgggc accgtctcgt acctggcccc ggagcagatc
    17761 cgccaggagg acaccgacca gcgggtcgac gtctacgcgg cgggcatcct gctgtacgag
    17821 atgctgaccg gcaccaggcc gcacaccggg gagcacgccg cccaggtgat gtaccggcac
    17881 ctgcacgagg acgtcccggc gccgtcccgg accgcgcccg cggtcggccc ggagctggac
    17941 gcgatagtcg cggcggcgac cgcccgcgac ccggaggccc ggccgtggga cgcggtggag
    18001 ctgctggccg ccgtgcagcg ggcccgccgc tcgctgcccc cggcccggct ggacgcggag
    18061 ccgcccgcct cgacccggcc caccccggtg cacaacccgg gcgaggccac cgccgtgatc
    18121 gagaccgcgc acccgatgga ccgcaccagc gtgctggagg tcccgccgga actgctgccg
    18181 ccggtgcgcc cggcggtgaa cgacgacccg ccgcgcggcc tgcccggccg ggcccgccgc
    18241 tcgggctacg gccgccgccc gctgatctgg tcggcggcgc tggtcgcgct gctgctggtg
    18301 gtcggcggca tcacgtacgc gctgtccagc gcggtgtacg cgacggtgcc gagcgtgctc
    18361 gggcagagcc gggagcaggc cgccgcgacg ctcgacaagc agggcctgca cggcgcgttc
    18421 accgagcagt acagcgagtc ggtgcaggcc gggcaggtca tctcgaccga cccgggggtc
    18481 ggcgcgaagg tccgcaagag cgactcggtg aaggtgctgc tctcgcgcgg cccggagcgg
    18541 ctccaggtgc cggacgtcac cggccgcccg ctggcggacg cccggaaggc gctcggcgac
    18601 gcccggctga ccgcgggcac cagcggcgag gagttcagcg acaccgtgcc gaagggctcg
    18661 gtgatctcca ccgccccggc ggcgggcagc agcctggccc cgaacgcgcc ggtggcgctg
    18721 accgtctcca aggggatgca cctcgtcccg gacgtcggcg gcctgagcaa ggaggacgcc
    18781 tcggccgccc tgaccgcggc cggcttcgtc ccgcaggtca ccggcctgct gccgctcggc
    18841 aaggtcaccg gccagtcccc cgcggccggc accccggccc ggcagggcag cacggtgacg
    18901 atcgcggtca gcctgttcta gccgctccgg tgccgcgccc gcgggttcag cgcagcggcc
    18961 cgtcgccggg cagctcctgg tacgagtagc gctgctcccg ccaggggtcg gcgaggttgt
    19021 ggtagccgcg ctcctcccag aagccgcgcc ggtcggcccg catgtactcg acggcgcgca
    19081 cccacttggg gcccttccag gcgtacaggt ggggcaccac cagccggacc gggaagccgt
    19141 gctccagggt gagcggccgg ccgtcgtggt gggtggcgaa gacggtggcc gggtcggcga
    19201 agtcggcgag ccgcaggttg gcgctgtagc cgtactcggc ccacaccatc acgtgggtga
    19261 cgcccgggtc gggcgggacg aggtcgagga cggtcgcggc ggcgacgccg gcccactcgt
    19321 tgccgagcat cgagaacttg gtgacgcagt ggaagtcgcc gcggacggtg gtcttgggca
    19381 gcgcgtggaa ggccgcgaag tcccaactgg ccttctccgc gtcggcggtg gccccgaaca
    19441 cctggaagtc ccagctctgc ggcttgaacc ggggcaccgg cccgtagtgc aggacgggcc
    19501 agccgcgctg cggccgctgt cccgggggga gcctcgggtc agtcgacggc tgctgttccg
    19561 gttcctgctg acccatgccc ccatggtgac agacggcgga cgccgaatcg cgcgcgcccc
    19621 cgccgcacgc ccccggggaa ataccggccg gcggaggggg gcaacacccg gcgaatacgc
    19681 gcgcgcgttc gatgcagata ccgccgaatg gcccaatcga tcggacatcg ccgcaggtca
    19741 gagcggtgcg aacggggcgt gaaaaccacc ggggggcgcg tctgtaagcg tgaacttact
    19801 ggaagtgcac ccgttcagct gccacgatgc ggggcatccg gagaccgacc ggaatgcgca
    19861 ccaggaaggc aggccatgca gggcgacccc gaggtcatcg agttcctcaa cgagcagctg
    19921 accgccgaac tcaccgccat caaccagtac ttcctgcacg cgaagatgca ggagaacttc
    19981 ggctggacca agctcgccaa gtacacccgg cacgagtcct tcgacgagat gaagcacgcc
    20041 gaggtgctga ccgaccggat cctcttcctg gacggcctgc cgaactacca gcggctgttc
    20101 cacgtccgga tcgggcagac ggtcaaggag atgttcgagg ccgaccggca ggtcgaggtc
    20161 gaggcgatcg accggctcaa gcgcggcatc gtggtgatgc gcgccaagaa cgacatcacc
    20221 tcggcgaaca tcttcgagtc gatcctggcg gacgaggagc accacatcga ctacctggac
    20281 acccagctgg agctgctgga caagctcggc gaggcgctct acatcgcgca gctgatcgag
    20341 cagccggaga gctgaggacg ccggaaggct caggacgccg ggggctcagg cggcctgcgg
    20401 ggcggtgacg gccgcggtgg cggcggccgg gtcggccagg ccgaggcgct cggccagccg
    20461 ggcggtgggg caggggcggg cgccgtgctc gccgagcagc gcctggatcc ggcgcacgca
    20521 ggagccgcag tcggtgccgg ccttgcagcc ctgggctatc tggcgggggg tgttggcccc
    20581 ctcgtcgatc ttctgcttga cctgggcctc ggtgaccgcg tggcacatgc acacgtacat
    20641 gtgctgcccc ttccacgatt gctgcggttt actgagcctt accttacctg gtgctccggg
    20701 cacgaagaag gcccctccgt ctcggaacgt ccgaaaccgg aggggccttc gtcacaccta
    20761 ccgcgcgggc ctcactggcc ccggtacatc tcggcgacca ggaacgccag gtccagcgac
    20821 tggctgcggt tgagccgcgg gtcgcaggcc gtctcgtagc gctggtgcag gtcgtcgacc
    20881 agcacctcgt cgccgccgcc gacgcactcg gtgacgtcgt caccggtcag ctcgacgtgg
    20941 atgccgcccg ggtgggtgcc gagcgcgcgg tgcacctcga agaagccccg gacctcgtcc
    21001 agcacgtcgt cgaacttgcg ggtcttgtgg ccgctggacg cctcgtaggt gttgccgtgc
    21061 atcgggtcgg tgatccacac gacctgggcg ccggaggcgg tgacctt
//
