LOCUS       NC_017030              26718 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Corallococcus coralloides DSM 2259, complete sequence.
ACCESSION   NC_017030
VERSION     NC_017030.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus coralloides DSM 2259
  ORGANISM  Corallococcus coralloides DSM 2259
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Kneip,S., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Complete genome sequence of the fruiting myxobacterium Corallococcus
            coralloides DSM 2259
  JOURNAL   J Bacteriol 194 (11), 3012-3013 (2012)
   PUBMED   22582372
REFERENCE   2  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2012) Ecophysiology, Max Planck Institute for
            Terrestrial Microbiology, Karl-von-Frisch Strasse 10, Marburg, Hesse
            35043, Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method :: Newbler v. 8/10/2010; Celera v. 8/10/2010
            Coverage                          :: 42-fold
            Sequencing Technology             :: Sanger dideoxy sequencing; 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000255295.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:27:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,155
            CDSs (total)                      :: 8,082
            Genes (coding)                    :: 8,042
            CDSs (with protein)               :: 8,042
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 11 of 40
            Pseudo Genes (incomplete)         :: 26 of 40
            Pseudo Genes (internal stop)      :: 6 of 40
            Pseudo Genes (multiple problems)  :: 3 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5825524
            Orig. end                         :: 5852242
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003389.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26718
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="25"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..26718
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26718
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16718](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16718
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(1325..3739)
                     /locus_tag="COCOR_RS23040"
                     /old_locus_tag="COCOR_04614"
     CDS             complement(1325..3739)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF020037.4"
                     /locus_tag="COCOR_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04614"
                     /product="PAS domain-containing protein"
                     /protein_id="WP_014397418.1"
                     /transl_table=11
                     /translation="MTVQWKPATDAAARVFPDGGELGALCRAKDWSAHPLGPVDGWPQS
                     LKTAVSMVLGSQFPLIVLWGPQLYQFYNDGYRLLMGTKHPGGLGQGNKECWPEVWHINE
                     TIYPRIFNGETVTYEERMYPLAPHGYPEEYFLTLCYSPVRDETGAVGGVLVSIFDVTRE
                     VRARNERDRALAEARAERERLYEVFMQAPAVIAVLEGPEHCFTVSNPLYQQLTGNRDLI
                     GKPLREALPEIGDQGFLQLLDNVRSTGKPYIAHDALVRLDRKGTGAVEDVYVDFVYQPL
                     KDASGSVFGIMAHAVETTEQVLARRSIEALAAERVAMLGHIADAVITFDTAGRVSFINE
                     MARTLYPGLRVGEPFAAQGFRQERVDGTPLSADELPPARAGRGERVLNEVWNIHTSDGH
                     RQRVQGSAVPVYTDTRVHLGVVLTLRDITQQHRLEQQLELERNRLTQVFMQAPASIMVA
                     RGPQHVIQVVNPGYDQMTGNRPLVGKTIPDAFPDLAGQGLFELYDQVYATKQPFVGNEV
                     PVRVARFGRVDDAYFNFVYQPLIDEDGETFGVMTHAVEVTDMVRSRQQAEERTRELVRL
                     TQALEQSNRELDQFAYVASHDLKAPLRGIANLAEWLKEELGSNLTVEAREFITLLHGRV
                     HRMEALIDGILTYSRAGKLSDPAAVDTGALLKEVVELLAPPPEAEVKVQPGSPTVSAER
                     VKLQQVFLNLIGNALKFTRLHRPDPRIQVTWRDAGEQYEFTVADNGPGIAPEFHERIWG
                     IFQTLESRDKVEGTGIGLSVVRKIIETRGGRAWVDSVPGEGAAFRFTWPKT"
     gene            complement(3741..4172)
                     /locus_tag="COCOR_RS23045"
                     /old_locus_tag="COCOR_04615"
     CDS             complement(3741..4172)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002622169.1"
                     /locus_tag="COCOR_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04615"
                     /product="response regulator"
                     /protein_id="WP_014397419.1"
                     /transl_table=11
                     /translation="MTTATSGDRTLHILLIEDDEVDVMNVRRAFQKNHIANPLYVATNG
                     LEGLEMLRNGAVPEGRRLVLLDLNLPKMNGIEFLRVLRADPELRTVSVVVLTTSADERD
                     KIDAYNLNVAGYLLKPVTFINFVEVMATLNKYWTLVEMP"
     misc_feature    complement(4237..4248)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     misc_feature    4300..4315
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            4472..5173
                     /locus_tag="COCOR_RS23050"
                     /old_locus_tag="COCOR_04616"
     CDS             4472..5173
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="COCOR_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04616"
                     /product="ATP-binding protein"
                     /protein_id="WP_167594364.1"
                     /transl_table=11
                     /translation="MRKALRQNSADLEQFTYVASHDLRAPLRGISNLSQWLEEDLGPQL
                     SQGSRRQMELLRGRVQRMEGMLDGLLDYSRAGRVHHKPEPVPVDRLIHETLERLAPGPS
                     ARLEVGPGMPVLVTERPALQQVFQHLLSNALKHAGREDVRIRVEVEATPAFHHFSVADD
                     GQGISSRYHEKIWSPFQTLVSRDKVEGAGMGLCVIKKLVESRGGRTWVESAEGAGATFH
                     FTWPGSEERLT"
     gene            5170..7719
                     /locus_tag="COCOR_RS45390"
                     /old_locus_tag="COCOR_04617"
     CDS             5170..7719
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013736.4"
                     /locus_tag="COCOR_RS45390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04617"
                     /product="response regulator"
                     /protein_id="WP_014397421.1"
                     /transl_table=11
                     /translation="MSDTPASTSSVEVPPLTERLRLLLVDDDEVDRLLVQRLLGTTGLA
                     VDVVEATSGSEALEQLKARSFDVILLDFFLPGEDGFWVLRELGSRGSRSPIVVLTGQGS
                     EQTAVELMKAGASDYIAKSRLSAERLEQSLRQAMRLHLAEQRHRALAEALPQIVWTAGP
                     DGRPDYFNQRWYDYTGLPARPASEERGSAPPLLPRDVLHADDVVGCLDRWSESRQAGGP
                     FECEGRIRRRSDGAWRWHLIQALPLRNAHGRILQWLGTCTDIDDQKRAAETLSFLAEAS
                     TMLTASLEMSVTLERLSALILPRLGDWCAVYLQDDDGPVRQAMAAHVDASRVPLLREQH
                     RAFNPSATASHGVARVLRTGMPELVPELTEAVLHEALGPAGDDARIRPGSWIIVPLWAQ
                     RRVFGALMVCALPSGRRYGARDMELVQELARRAEIAIDNARLFEMAKAEHLGAEQANRA
                     KDEFLAAVSHELRTPLMAMVGWTRMLRSGQLGPDKAARALEAVERNTQVQTQLIEDLLD
                     VSRIITGKMRLEIRPVVPGMFIEAALDSVRHAAEAKGVTLCAELPPGSGSIHGDADRLQ
                     QVVWNLLSNAIKFTPRGGQVTVRLRWVEGHVVIEVQDTGQGIPRAYLGQIFERFWQVDG
                     SSTRKHGGLGLGLAIVRHLTELHGGTIEATSQGEGHGALFRLTLPLATAASSRGSAPLV
                     QVQARQEVPSLDSGVLKGLQVLVVDDEPDALELLAVVLESRGAQVFTASSARQALEKHQ
                     FHRPHVIISDIGMPGEDGYSFIRRLRALPLEQGSQTPAIALTAFARMEDRTRALLAGFQ
                     MHVPKPIEPAELIIVLASLTGRHPQVDSQFQAARQAP"
     gene            complement(7734..8204)
                     /locus_tag="COCOR_RS23060"
                     /old_locus_tag="COCOR_04618"
     CDS             complement(7734..8204)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023580.4"
                     /locus_tag="COCOR_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04618"
                     /product="DUF3592 domain-containing protein"
                     /protein_id="WP_167594366.1"
                     /transl_table=11
                     /translation="MRNLLMILTFGGLFFGVIFGIGAWMIHSSAQAFLARPTVQGRVLE
                     MAVEMGYSKSRYWRVKARYAYEVDGQSYVGETLSNETPRELLLWNPQPSPALTRYVERY
                     PVGSTVTVRYNPKEPRRSLLEVNPDAARGPALAAGIALLVAVLSLVGQRFVR"
     gene            complement(8232..9905)
                     /locus_tag="COCOR_RS23065"
                     /old_locus_tag="COCOR_04619"
     CDS             complement(8232..9905)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="COCOR_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04619"
                     /product="S53 family peptidase"
                     /protein_id="WP_014397423.1"
                     /transl_table=11
                     /translation="MARIPLTQSARVSPASLHPPLRSRSATGTVEVTLLLRHGAPLPTV
                     EELCANPPRRPLTHDEFEAKYGTNPKHLAAVRRFAKSHGLTVTTERRDRGYVVLQGSTA
                     AVRKAFEVDLRRYTHGKRSYLTHTKPVRLPRALEGVAEWVLGLDTRPLVTHNAAALPIP
                     KEMAKQAGLRTYTAPQVANLYRYPRNQGEGQCVGIIELAGGYKQSDLDAYLKSMGVERT
                     APVVNVGPNKAGALNTASNAEVTMDVELVASVCPAARVVVYNAGSKDYSLRDYHRVLAE
                     AISDRENRPSVLTTSWSFYEGSLIQQGEELAFERLFIEAALLGITVCAASGDLGSQVPV
                     NAHSPTGAITLAATSYPAASALVLGCGGTTLEAVGDVLHHERVWNRLGEAMSMGPSSTA
                     AGASSGGVSTMNALPLYQQGMGVPDLVMSSWKNGVFSVSRSTGRGVPDVAANADLHTGY
                     QIVFKGQQGVAAGTSAAAPMWAALIVRLNEALGERVGFLHPRLYALVTEGQPVVRRITH
                     GGNGAYFASDATLWNACTGLGTPDGEALLTGLRRLQRRKH"
     misc_feature    9976..9994
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.57"
                     /tool="antismash"
     aSDomain        10001..10294
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_COCOR_RS23070_Goadsporin_CD_RRE.1"
                     /evalue="5.40E-20"
                     /identifier="RREFam013.1"
                     /label="COCOR_RS23070"
                     /locus_tag="COCOR_RS23070"
                     /protein_end="98"
                     /protein_start="0"
                     /score="62.3"
                     /tool="antismash"
                     /translation="MDRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVENVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLG"
     gene            10001..12193
                     /locus_tag="COCOR_RS23070"
                     /old_locus_tag="COCOR_04620"
     CDS             10001..12193
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613718.1"
                     /locus_tag="COCOR_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04620"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_014397424.1"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 1.6e-17,
                     bitscore: 62.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.7e-23,
                     bitscore: 80.7, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 1.5e-20, bitscore:
                     71.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 1.6e-87, bitscore: 293.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVENVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLGVGAATA
                     AGRLLDVSVSVHAVDGEDGEGLAEALRDTGLDVCDAADRRVLLVDDYLSQEALALAEEA
                     RSAGAAFLPLKVSGTACHAGPVVGTGERACWTCLTARLLDNRPIEKYLARKGTPPRAIR
                     PPRTGLPTTAKAGLSFAATLAARWVVDGPGRPGQTRLWTLDFATWKLESHAVARRPQCP
                     DCGDPHWMEARAKKPLELASRSKRFTDDGGHRILTPEQTWERHRHLISPVTGVVSDLRA
                     VPGDAPLGHIQSAVFRVCPWTDAPASDDFHRVASGKGRTEAQARAGALCEALERYSAVF
                     QGDEPRVHATASQLGAQAVHPDALQHFSSAQFQSRPETASRDMRTAVPRPYADQPMDWS
                     PAYSLTHGVHKYVPTSFAYLFAPPPPSGDGPFCFFNSNGNAAGNCVEEAILQGFLELVE
                     RDAVALWWYNRLRRPRVDLRSFDEPWFASVSAHYQSLGLQLSVLDLTHDLGIPVFAALV
                     WSPERGRAWAGCGCHFDAKLAVQRALTEVAQCYDPKDVSPSPWDASAHGDVSWLFPNDL
                     VPARVRADFPHMGHNDLRDDVRECVTRAASVGLETLVVEQSRPDVGVSAVKVIVPGLRH
                     FWPRLGPGRLYDVPVRMGWLKAPKTEAQLNPVPFYF"
     aSDomain        10004..10237
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_COCOR_RS23070_Cyanobactin_D_RRE.1"
                     /evalue="9.50E-26"
                     /identifier="RREFam007.1"
                     /label="COCOR_RS23070"
                     /locus_tag="COCOR_RS23070"
                     /protein_end="79"
                     /protein_start="1"
                     /score="80.7"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVENVIAALAGRASAPEVLYALSLLEERGHV"
     aSDomain        10004..10285
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_COCOR_RS23070_NHLP_CD_RRE.1"
                     /evalue="5.10E-23"
                     /identifier="RREFam015.1"
                     /label="COCOR_RS23070"
                     /locus_tag="COCOR_RS23070"
                     /protein_end="95"
                     /protein_start="1"
                     /score="71.9"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVENVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWE"
     gene            12197..14149
                     /locus_tag="COCOR_RS23075"
                     /old_locus_tag="COCOR_04621"
     CDS             12197..14149
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="COCOR_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04621"
                     /product="radical SAM protein"
                     /protein_id="WP_014397425.1"
                     /sec_met_domain="PF04055 (E-value: 7.9e-11, bitscore: 41.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPPPAPKPRILLVQCGPDRRHVDRETEDFDPERGLVKRATMTPL
                     ACATLAALTPDAFTVDIWDEELHGQLRADTELPDYDIVGVSVMYSALTYQARFLGGHFR
                     DRGATVVAGGPAISAAPEDYRGFFDALFVNEAERTWPRFLADWLGGEYAPEYRQLEKPS
                     LSESPLPRWDAIAADLPRYAWGSVQTTRGCPFDCSFCDVIYLYGRKQRHKPVERVLDEV
                     RAHAALGAEGVFFADDEFIGDAAYAKEVLAGLVPLNRALPRPLRFFTQVTMNLSRDAAL
                     LEGMADANFYTVVLGIESFDTGALKEAQKHQNVRADLVGDLLRIQAHGIGPRGSFIVGF
                     DHDTPAVFDSLHANIQRTHLPWVVVAPLQAPRGTKLWTRLRAEGRLATPRRAHAKDRGA
                     IVLNVMPLGMTRPQLLEGFRDLVERLSTWDAACERIRGFIAGIQRPPQVEEPHWPEAVT
                     DRFLREATAAWALTPSERHALGDTLAQVRRTAPAMLPRAVFFLARNQNERRRHERLFTD
                     FDAVLAAERQGDLVPDTQPVYVPPGFATAMRDVFPDLFVRLSRDLPDRRDVPEASRDVL
                     VDFVARWGEGFQALQPQHHEFLRELCDREVAARGGHPGTLEVVEEQALRTQARRTGLLE
                     ALLKDVRDELASWGP"
     gene            14153..15310
                     /locus_tag="COCOR_RS23080"
                     /old_locus_tag="COCOR_04622"
     CDS             14153..15310
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613725.1"
                     /locus_tag="COCOR_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04622"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_014397426.1"
                     /transl_table=11
                     /translation="MRDGLHIFDADRHVLEPLSLWAEQLEPGLRRHAPRPGRLPDETLE
                     ERLERLGPQGLLPVLPLPEVDGKPLWNHMPEKAWLAFSERSYAQLGRNELLQRPDVYLA
                     QMDRDGVDMAALFPTYALLLEGFSPLEPHVATAFASVYNTWLHGFCAHQPERLRGVGLI
                     SRHQPEAMVAEVRRVAGFGWRAVMVRPNPIGGRLLSDAAYEPFWSECEKLSLAVVLHGS
                     GHVYVPSAGADRFDTRFANHVCAHPMELMMGLLALLQGGVLERHPALRIGAMEAGCGWL
                     PYWAWRLDEEYRAVGAEVSATIRQLPSAYLRQHCFVSVEPDEPYLPDVVRHLPEDRLVF
                     GSDFPHLDHGEDVLGAMLSLRDVMTESRLRKVLWENPTRFYGVEP"
     misc_feature    complement(14181..14195)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.98"
                     /tool="antismash"
     gene            15321..16718
                     /locus_tag="COCOR_RS23085"
                     /old_locus_tag="COCOR_04623"
     CDS             15321..16718
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03605.1"
                     /locus_tag="COCOR_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04623"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_014397427.1"
                     /sec_met_domain="PF00881 (E-value: 8.2e-06, bitscore: 24.9,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSLAEGVALRCPDAEDARVEGPGRSLRLGPLAPGVRAVFESLA
                     DGGIHETEVPAAAGSDTTLAWYWLDLAGDGGLLSWTVEERGNLLLTLTPASASFLRHRA
                     TFDASQPLQLSRFAHTRMAEGRAVLDCPTVHATAALHDRRVVSLLFDMARPTLLARLNQ
                     FNTGIESFTLRELVRLLAETGILVPNGLDVPASEETQTALKQWEPHDLLFHLRSRGWGH
                     QTRAGATYRFRGELPNPPALKPTVTEEVVELHRPDLEALRAGGDRSFTEVLEARRSLRG
                     RGASPLNVKQLGELLYRAARVRAVRTTQDGEITDRPYPGAGAVYALELYPMVGECQGLP
                     PGAYHYDPLGHRLEKLSGPTPEFHALLDEARAPAEPFERPEVLMVVAARVPRLAWKYET
                     LAYSLVLQDTGALVQTLYLVSTAMGLRPYALGRSDPDFFQRVAGVDGFGEASVGAFAVS
                     GGESPDR"
     gene            complement(16737..17150)
                     /locus_tag="COCOR_RS43805"
                     /old_locus_tag="COCOR_04624"
     CDS             complement(16737..17150)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03795"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03795.1"
                     /locus_tag="COCOR_RS43805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04624"
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_014397428.1"
                     /sec_met_domain="TIGR03795 (E-value: 9.1e-22, bitscore:
                     76.2, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKKPESKAAPARARPVARKPTRGPEAKASVNDWQAVWMRAVAL
                     AWKEPEFEAALQKDPRQALKKRFDFDLPASIQLKVVPSSVKDAAADGTWKVNSAEVELH
                     LPKKPADVADHAVALSSLTDTHGRSHCCGSPCC"
     gene            complement(17152..21243)
                     /locus_tag="COCOR_RS23095"
                     /old_locus_tag="COCOR_04625"
     CDS             complement(17152..21243)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR03903.1"
                     /locus_tag="COCOR_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04625"
                     /product="TOMM system kinase/cyclase fusion protein"
                     /protein_id="WP_043323562.1"
                     /sec_met_domain="Pkinase (E-value: 4.8e-50, bitscore:
                     169.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPQLLEAFQGRYELLSELGEGGFGRVYKARQVTTGQNVAVKLLR
                     LTDGATPESVERRSARFEREMKLCAQMHHPNIVRLIDSGRAQGGAVYSIFEFVPGKNLA
                     QVLAEEGVLDPVEARHLMLQLLDALACAHAQNVVHRDLKPANIMVVPTGARRNALVLDF
                     GIGSVTDELTRTEAQPRITSTNESLGTPSYAAPEQLRGQAPTPRSDLYAWGLVFLECLT
                     GRRVFEGATVAEVIFQQLSSEPVPIPSAIAAHPLGKLLQRVTAKDPSQRTVSAEVLLRQ
                     LEAVDVSNLPRRPAPVRIQPAAPNAETATVELSSRTPNAVSTRSRRWAEGERRQLTVVC
                     CTLSATQTAPGPVDIEELDHVLGAQQEVCIEIARRYNGHIASALGDIVLFYFGYPAARE
                     DDARRAAQAALDMVAEVKRRGRAIEAERGTRVEIRVGLHTGLVVSREQRDPTLSGLGFV
                     VGTTPKLAFRLSTSAPSGAILVTGDTQQLVRKHFPLEPTPASPNELLPPGLETFVLQGA
                     DATWSGTDEALSLVGRTRELDLVLSRWEQARSGQGQVVLISGEPGIGKSRLMRELGDRL
                     GAEPHTWLEARCTEDSSGQAYAPVVDLLTRMLDPNRDLPPEGRLTGLEALLSGYSFELP
                     ETLPLFASLLSLPLPPERWAPLDVSPLKHRELTRNALLAFLAAMAERQPVVLALEDLHW
                     ADPSTLELLKALVEEVSSSRLLAVFSARPELEPPWAASAVTQVQLGALARAEVERLATA
                     AAGGPLSPEALEEISTRTDGIPLFVEELVRTLRESGALVEREGRFALEASKAGPSVPGT
                     LRDLLVARLDRLGRAKETAQIASVLGRELTHELLRHVSPLTPEALEADLERLVGSGLLH
                     RKRRPKGPVYLFKHALVRDAAYDSMLKRYRQQMHAKTAEAMEAHFQEQVESRPDLLAHH
                     WAAANLKRKAILYAQKAAFAALVRSAYLEAILFARLGLSWLDAIDDPVERAQLELSLNG
                     VLAPALMSTQGWRSQDLRNVAERSLELLFTVGESPYAAPTLWVLSIFYHLGGDQRRVRG
                     LLDRLVALAQRSGDAGQEAVALTILSNIELLEGRLGEAKAKADRCLSLFDPVAHRMHRI
                     LYGQDTRVGGESVLCRGKWLLGFPDQAKAHGEAAVAWGRELNHGTSIGLSFIYLLLIAQ
                     EHGDRTEALQLISQHSELSHRYGLLEQAAYVGILRAWAVKDLEAMRRGIALREAFGTEM
                     DQPAYYAMLAELELELGHVEAALASVERGQQRAQALGEAYHESKMLHVKGRVLLQRDGN
                     TALSAETCFRQAAEVAHAQGARMRELQAVTALARVLQASGRQEEARQRLQTVYSTFSEG
                     WGTPPVSEARALLDALGGER"
     gene            complement(21252..23045)
                     /locus_tag="COCOR_RS23100"
                     /old_locus_tag="COCOR_04626"
     CDS             complement(21252..23045)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024583.4"
                     /locus_tag="COCOR_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04626"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_014397430.1"
                     /transl_table=11
                     /translation="MLVYNPGQPDELSYPLGDAPITIGRADDQGICIPHRSLSRQHARI
                     EPSDGRFFVTDLQSKNGTFVNGVQIRRKELRPGDTLTLGELVFLLTHEAPPAVPAGPPG
                     SGSASGASGEPRPQLTRALTRVPLKTLVQAVSGSEKSAEEAPGTATRARERMRILQEVA
                     KLLSVTDDLEALPGRVLDLAFQILHVERGAILLVDEGTGKLEPRVTKTAEGTAVRGPIY
                     SQNIVDFVLRRSVAALFSDAVNDPRLGAAESVIFSSIRASMCVPLKPRDEVLGVLYVDN
                     VSTPKSFSEDDLEFLVAFAGQAALALENARLYRRIEQETVQRMQLIMDAKLASLAALVG
                     GMAHELRNPLNFISNFAGLSVGLTEDLAGVLEPQRERLTADSVRDVDEALACLRTNVQK
                     INEHGRRADALIQNMLQHARRSPGPREAVELNALVAESVALGQGGMRGEPLTVRLEAEY
                     DPAVERLELSRADVGRVIINVVDNALYAMRQKRQAQGAAYVPVLKVRTLARPEQVEVRL
                     RDNGPGIPAESAGRIFDPFFTTKPPGQGTGLGLSLSHDIIVQGHQGTFRMETVPGEFTE
                     FVITLPRRGGRSSMERGSGTR"
     gene            complement(23120..23680)
                     /gene="cysC"
                     /locus_tag="COCOR_RS23105"
                     /old_locus_tag="COCOR_04627"
     CDS             complement(23120..23680)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553518.1"
                     /locus_tag="COCOR_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04627"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_014397431.1"
                     /transl_table=11
                     /translation="MQQRPGFILWFTGMSGAGKSTLSTAVARQLSPVQRVELLDGDEVR
                     TYLSRGLGFSRADREENVRRIGYVARVLAKHEVGVITAAISPYKSSRDEVRALATQAGI
                     PFLECYVQASLDALIARDVKGLYKKALAGEIPHFTGVSDPYEPPESPEITVRSDAETVE
                     AGVERILDTLRDRGLLAPAASAA"
     gene            complement(23691..24956)
                     /locus_tag="COCOR_RS23110"
                     /old_locus_tag="COCOR_04628"
     CDS             complement(23691..24956)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350034.1"
                     /locus_tag="COCOR_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04628"
                     /product="GTP-binding protein"
                     /protein_id="WP_014397432.1"
                     /transl_table=11
                     /translation="MELLRFATAGSVDDGKSTLIGRLLYDTKSILEDQLAAVERTSHAR
                     GDEYVNLALLLDGLKAEREQGITIDVAYRYFSTAKRKFIIADTPGHLQYTRNMVTGAST
                     ADLALILVDARKGVLEQTRRHAFIASLLRVPHLVLCVNKMDLVDYDQGVFDRIREEFRQ
                     FSMKLDVSDLSFIPISALGGDNVVTRSEKMAWYQGPTLLHHLENVHIASDRDLIHLRFP
                     VQGVIRPASAKKFHDYRAYSGQLLGGVMRPGDEVMVMPSGFTTRIKSLELAGKPLKEAF
                     PPMSVNVSLEEELDISRGDMLCRPGNPPTASQDIDAMVCWLSDSTQLNSGSRLAIKHTT
                     RMARAMVKNLHYRLDVNTLHRDEQSSGLKLNEVGRVTLRTTVPLFFDEYRRNRSTGSFI
                     LVDEGTNATVGAGMINGPAVDR"
     gene            complement(24956..25867)
                     /gene="cysD"
                     /locus_tag="COCOR_RS23115"
                     /old_locus_tag="COCOR_04629"
     CDS             complement(24956..25867)
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350035.1"
                     /locus_tag="COCOR_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04629"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_202801727.1"
                     /transl_table=11
                     /translation="MSVSYELSHLEALEAESIFIIREVAAELDRPVLLFSGGKDSAVML
                     HLAVKAFWPAPLPFPLMHVDTGHNFPEVIQYRDERVAELGARLIVASVQEAIDAGKVTE
                     EKGPRASRNRLQTQPLLEAIEKNGFNAVFGGARRDEEKARAKERVYSFRDEFGQWDPKN
                     QRPELWALYNGRHRRGEHLRVFPLSNWTELDIWQYIGRENVALPSIYYTHRREVFRRDG
                     MLMAWSPFMSMMPGETVTTETVRFRTVGDMTCTACVPSTASTVEQVIAEVTASRVTERG
                     ASRADDKFSETAMEDRKREGYF"
ORIGIN
        1 ctccaagggc gagtccctgg agccgctcta cgccaaggtg ccggacatgc tccgcggctt
       61 cgtggagctg cactacgacc tggcccaccg cgccaacgcc cgcatcatgg agccgctgct
      121 ctaccgcagc agcctctaca aggaatccgc gcagagcatc tcgctgatgc gcgtggccgg
      181 tgacgcgcgc aagtacgtct tcagcacccc gcgcctggag ggcgactccc ccctctggct
      241 ccaggtgccc taccggcacg agggcatcga cgccctcttc cgcatgcgcc acacgccggg
      301 cagccccggt caggtggcgg agatgctggg cgtgccgtcc tccgccgcgg aggccttcgc
      361 ggacctcttc acggagaccg ccccgcgcaa gcccgagccg tacacgggct ccggcgtgcg
      421 cgtgcgctac ttcggccacg cgtgcgtgct gatggagacg cgggaggtgt ccgtcctcac
      481 cgaccccgtc atcagctacg agttccccac ggaccagcgc cgcttcaccc acgcggacct
      541 gccggagaag atcgactacg tcctgatcac ccacggccac gcggaccacc tgatgatgga
      601 gacgctgctg caactgcgtc accgcatcgg gaccatcgtc gtgccccgct cgaacgcgta
      661 ctcgctggcg gacccctcgc tgcgcctggt gctggagaag acgggcttca agaacgtcat
      721 cgagatcgac gacctgcagg agattcaaat ccccggcggg tcgctgatgg gcatcccctt
      781 catcggcgag cacagcgacc tggcggtgca ggcgaagacg gcgcacctgg tgcggctggc
      841 cggccgctcg ctgctgatgg ccgcggactc caacgcgctg gagccgcgca tgtaccagca
      901 cctgtcggag ctggtgggcc cgctggacgc gctctacctg ggcatggagt gcgagggcgg
      961 cccgatgagc tggatgtacg gcccgctgct cagccagccc ctgccgcgca agatggacca
     1021 gtcgcggcgg ctcaacggct ccgacagcgc ccgcgccacg gagatcctca atcacctgaa
     1081 cccgaaagag gtcttcatct acgccatggg ccaggagccc tggctgcgcc acgtgatggt
     1141 gctccagtac gacgagaccg cgccccagat gatcgaatcc aacaagttca tcgaggtctg
     1201 caagggccgc agcatccccg ccgcgcggcc cttcctgagc atggagcgca tcctggagta
     1261 gccgcgcgcc cacgcccggt ggcgccccct cctcggatga ggcagggcgc cccgggggag
     1321 cgcgtcacgt cttgggccag gtgaagcgga acgccgctcc ctcgcccggc acggagtcca
     1381 cccaggcccg gccgccgcgg gtttcgatga tcttccgcac cacggacagc ccgatgccgg
     1441 tgccctcgac cttgtcgcgg ctctccagcg tctggaagat gccccagatg cgctcgtgga
     1501 actccggtgc gatgcccggg ccgttgtccg cgacggtgaa ctcgtactgc tcccccgcgt
     1561 cccgccacgt cacctggatg cgcggatccg gccggtgcag gcgggtgaac ttgagcgcgt
     1621 tcccgatgag gttcaggaac acctgctgca gcttcacgcg ctcggcgctc accgtgggcg
     1681 agcccggctg caccttcacc tccgcttcgg gcggcggggc cagcaactcc accacctcct
     1741 tgagcagggc gcctgtgtcc acggcggccg gatcactcag cttgcccgcg cgggaatagg
     1801 tgaggatgcc gtcgatgagc gcctccatgc ggtgcacgcg gccgtgcagg agcgtgatga
     1861 actcacgcgc ctcgacggtg aggttggagc ccagctcctc cttgagccac tccgccaggt
     1921 tggcgatgcc gcgcagcggc gccttgaggt cgtgcgaggc cacgtaggcg aactgatcca
     1981 gctcgcggtt ggactgctcc agcgcctggg tgagccgcac cagctcccgc gtccgctcct
     2041 ccgcctgctg gcgggagcgc accatgtcgg tgacctccac cgcatgggtc atgacgccga
     2101 aggtctcccc gtcctcgtcg atgagcggct ggtagacgaa gttgaagtac gcgtcgtcca
     2161 cccggccgaa gcgcgcgacc cgcacgggca cctcgttccc gacgaagggc tgcttcgtgg
     2221 cgtacacctg gtcgtagagc tcgaagaggc cctggcccgc caggtccggg aacgcgtccg
     2281 ggatggtctt ccccaccagg gggcggttgc ccgtcatctg atcgtagccc gggttgacca
     2341 cctggatgac gtgctggggc ccgcgggcca ccatgatgga ggcgggcgcc tgcatgaaga
     2401 cctgggtcag ccggttgcgc tccagctcca gctgctgctc caggcggtgc tgctgggtga
     2461 tgtcacgcag ggtgagcacc acgcccagat ggacgcgggt gtcggtgtac accgggacgg
     2521 cgctgccctg gacgcgctgc ctgtggccgt cggacgtgtg gatgttccac acctcgttga
     2581 ggacgcgctc cccccgcccc gcccgcgccg ggggcagctc gtcggcggag agcggcgtgc
     2641 cgtccacccg ctcctgtcgg aagccctggg cggcgaaggg ctcgcccacg cgcaggcccg
     2701 ggtagagcgt ccgggccatc tcgttgatga agctgacgcg gcccgcggtg tcgaaggtga
     2761 tcaccgcgtc ggcgatgtgg cccagcatcg cgacgcgctc ggccgccagc gcttcgatgc
     2821 tcctgcgcgc cagcacctgc tccgtggtct ccaccgcgtg cgccatgatg ccgaacacgc
     2881 ttccgctcgc gtccttgagc ggctggtaga cgaagtccac gtagacgtcc tccaccgccc
     2941 cggtgccctt gcggtccagg cggaccagtg cgtcgtgcgc gatgtagggc ttgccggtgg
     3001 acctcacgtt gtccagcagc tgcaggaagc cctgatcccc gatctcgggc agggcctcgc
     3061 gcaggggctt gccgatcagg tcccggttgc ctgtcagctg ctggtacagc gggttggaga
     3121 cggtgaagca gtgctcgggc ccctccagca cggcgatgac ggccggggcc tgcatgaaga
     3181 cctcgtacag gcgctcgcgc tccgcccgcg cctccgccag cgcgcggtcg cgctcgttgc
     3241 gcgcccggac ctcccgggtc acgtcgaaga tggagacgag gacgccgccc acggcgcccg
     3301 tctcgtcgcg gaccgggctg tagcagagcg tgaggaagta ctcctccggg tagccgtgcg
     3361 gcgcgagcgg gtacatccgc tcctcgtacg tgaccgtctc cccgttgaag atgcgcgggt
     3421 agatggtctc gttgatgtgc cacacctccg gccagcactc cttgttgccc tgccccaggc
     3481 ccccggggtg cttggtgccc atgagcaggc ggtagccgtc gttgtagaac tggtagagct
     3541 gtggccccca caggacgatg agcgggaact gcgagcccag caccatgctc accgcggtct
     3601 tgaggctctg gggccagccg tccacggggc ccagcggatg cgcgctccag tccttcgccc
     3661 ggcacagcgc gcccagctct ccgccatcgg ggaagacccg ggccgctgcg tcggttgctg
     3721 gcttccactg cacggtcatg tcagggcatc tccacgaggg tccagtactt gttgagcgtg
     3781 gccatgacct ccacgaagtt gatgaaggtg acgggcttga gcaggtagcc ggcgacgttc
     3841 aggttgtacg cgtcgatctt gtcccgctcg tccgcggacg tggtgagcac caccacggag
     3901 acggtccgca gctccggatc cgcgcgcagc acgcgcagga actcgatgcc gttcatcttc
     3961 gggaggttca agtccagcag caccagccgg cgcccctcgg gcaccgcgcc gttgcgcagc
     4021 atctccaggc cctccagccc attggtggcc acgtagaggg ggttggcgat gtggttcttc
     4081 tggaaggcgc ggcggacgtt catcacgtcc acttcgtcgt cttcaatcag caggatgtgc
     4141 agcgtcctgt caccggaggt agcggtggtc atgcctgagc ctttcgagcc tgcgcggcgt
     4201 ccagacccaa gaggagcccg agcacgctgg catctagcgt tcgcttccgt gcggatatca
     4261 ggcacgttcg ggcaactgtc tgcttcctga cgcgactctt cgcacgcctg ctcgggaagg
     4321 cgcctggaga gtgtcgacca tccttcactt cgcgcccatg ggttgagggc cctcgcgcgg
     4381 ggacggtatg gcgataggcc ctgtgcgccg tccccctccc atggatgact cccagaaaac
     4441 aaaggatgcg ctcctcgagg agctccagga cttgcgcaag gccttgcggc agaacagcgc
     4501 cgacctggag cagttcacct acgtggccag tcacgacctc cgggccccgc tgcggggcat
     4561 ctccaacctg tcgcagtggt tggaggagga cctggggccg cagctgtccc aggggtcacg
     4621 caggcagatg gagctcttgc gcgggcgcgt gcagcggatg gagggcatgc tggatggcct
     4681 gctggactac agccgggcgg gccgcgtcca ccacaagccc gagcccgtgc cggtggaccg
     4741 gctgatccac gaaacgctgg agcgactggc ccccggacct tccgcgcggc tggaagtggg
     4801 tcccgggatg ccggtgctcg tcacggagcg tcccgcgctc cagcaggtct tccagcacct
     4861 gctctccaac gccctgaagc acgcgggccg cgaggacgtg cggatccgcg tggaggtgga
     4921 ggccaccccc gccttccatc acttctccgt cgcggatgat ggccagggaa tctcctcccg
     4981 ctaccacgag aagatctgga gtccgttcca gacgctcgtg tcgcgcgaca aggtcgaggg
     5041 cgccggcatg ggcctgtgcg tcatcaagaa gctcgtggaa agtcgcggcg gccggacctg
     5101 ggtcgagtcg gccgaaggcg cgggcgccac cttccacttc acctggcccg ggtccgagga
     5161 acgcctcacg tgagtgacac ccctgcctcg acttcctccg tggaagtccc tcccctgacc
     5221 gagcgtctcc ggctgctgct cgtcgatgac gacgaggtcg accggctcct ggtccagcgg
     5281 ctcctcggca cgaccggact cgcggtggac gtggtggagg ccacgagcgg aagcgaggcc
     5341 ctggagcagc tgaaggcgcg gtccttcgac gtcatcctcc tggacttctt cctgccaggg
     5401 gaggacgggt tctgggtgct gcgcgagctg ggcagccggg gctcgcgctc tcccatcgtc
     5461 gtcctcacgg gccagggcag cgagcagacg gccgtcgagc tgatgaaggc gggcgcgtcc
     5521 gactacatcg ccaagagccg gctgtccgcg gagcggctgg agcagagcct gcgccaggcc
     5581 atgcggctgc acctggcgga gcagcggcac cgggcgctcg cggaggccct gccgcagatc
     5641 gtctggacgg cgggcccgga cggacgcccg gactacttca accagcgctg gtacgactac
     5701 accggcctgc cagccaggcc cgcgtcggag gagagaggga gcgcgccccc cctgctcccc
     5761 cgggatgtcc tccatgccga tgacgtggtg ggctgcctgg accggtggag tgagagtcgg
     5821 caggcggggg gacccttcga gtgcgagggc cgcatccgcc gccgctcgga cggcgcctgg
     5881 cgctggcacc tcatccaggc cctgccgctg cgcaacgcgc acggccgcat cctccagtgg
     5941 ctgggcacct gcaccgacat cgatgatcag aagcgcgcgg cggagacgct gagcttcctg
     6001 gcggaggcga gcaccatgct caccgcctcg ctggagatgt ccgtcacgct cgagcggctc
     6061 tccgcgctga tcctcccgcg gctgggagac tggtgcgcgg tctacctcca ggacgacgac
     6121 ggccccgtgc gccaggcgat ggccgcccac gtggatgctt cacgggtgcc gctgctgcgc
     6181 gagcagcacc gcgccttcaa tccgtccgcc accgccagcc acggcgtcgc gcgggtgctg
     6241 cgcacgggca tgccggagct ggtgcccgag ctcaccgagg ccgtccttca tgaggccctg
     6301 ggcccggcgg gtgacgacgc gcggatccgc ccggggtcgt ggatcatcgt ccccctgtgg
     6361 gcgcagcggc gcgtcttcgg ggcgctgatg gtgtgcgccc tcccgtccgg ccgccgctac
     6421 ggcgcgcggg acatggagct ggtgcaggag ctggcgcggc gggcggagat cgccatcgac
     6481 aacgcccggc tgttcgagat ggccaaggcc gagcacctgg gcgccgagca ggccaaccgc
     6541 gccaaggacg agttcctggc cgcggtctcc cacgagctgc gcaccccgct gatggcgatg
     6601 gtgggctgga cgcggatgct gcgctcgggg cagctggggc cggacaaggc cgcccgggcc
     6661 ctggaggcgg tggagcgcaa cacgcaggtg cagacgcagc tcatcgagga cctcctcgac
     6721 gtgtcgcgga tcatcaccgg caagatgcgg ctggagatcc gtccggtggt ccccggcatg
     6781 ttcatcgagg cggcgctgga ctcggtgcgg cacgccgccg aggcgaaggg cgtcacgctc
     6841 tgcgccgagc tgccgccggg ctccggctcc atccacggcg acgcggaccg gctgcagcag
     6901 gtggtctgga acctgctctc caacgccatc aagttcacgc cccggggcgg ccaggtcacc
     6961 gtgcgcctgc ggtgggtgga gggccacgtc gtcatcgagg tccaggacac cggccagggc
     7021 atcccccggg cctacctggg ccagatcttc gagcgcttct ggcaggtgga cggaagctcc
     7081 acccggaagc atggcggtct gggactgggg ctggccatcg tgcggcacct cacggagctg
     7141 cacgggggca ccatcgaggc gacgagccag ggcgagggac atggcgccct gttccggttg
     7201 acgctgccgc tggcgaccgc ggcctcgtcg cggggaagcg cgcccctcgt ccaggtccag
     7261 gcgcgccagg aagtaccctc gctcgattca ggcgtgctga agggcctgca ggtgctggtg
     7321 gtggacgacg agccagacgc gctcgagctg ctcgccgtgg tgctggagag ccgcggggcc
     7381 caggtcttca cggcctccag cgcccgccag gcgctggaga agcaccagtt ccaccgccct
     7441 cacgtcatca tctccgacat cggcatgccg ggagaggacg gctattcctt catccgcagg
     7501 ctgcgcgccc tgccactgga gcagggaagc cagacgccgg ccatcgcgct caccgccttc
     7561 gcgcggatgg aggaccgcac ccgggcgctg ctcgcgggct tccagatgca cgtgcccaag
     7621 cccatcgagc cggcggagct gatcatcgtc ctggcctcgc tcaccgggcg gcacccgcag
     7681 gtggactcac agttccaggc cgcccgccag gcgccgtgac cgcacggcgc gggctagcgc
     7741 acgaaccgct ggcccaccag gctcagcacc gcgaccagca acgcgatccc agcggccagc
     7801 gcggggccac gcgctgcgtc cggattcacc tccagcaggc tgcgccgggg ttccttcggg
     7861 ttgtagcgaa cggtcaccgt ggagcccacc ggatagcgct ccacataccg cgtcagcgcc
     7921 ggactgggct gggggttcca gagcaggagc tccctcgggg tctcattgga gagcgtctcc
     7981 ccgacgtacg actggccatc cacttcgtag gcgtaacgcg ccttcacgcg ccagtagcgg
     8041 cttttcgagt agcccatctc caccgccatc tcgagcacgc gcccctgcac cgtcggccgg
     8101 gccaggaagg cctgcgccga ggagtggatc atccaggcgc caatcccgaa gatcacgccg
     8161 aagaacaagc cgccgaacgt gaggatcatc aagaggttac gcatccacat gccccatgag
     8221 cgctcgactc ctcagtgctt gcggcgctgg agcctgcgca ggcccgtgag caatgcctcg
     8281 ccgtccggcg tgcccagacc cgtgcacgcg ttccacagcg tcgcgtcgct ggcgaagtac
     8341 gcgccgttgc cgccgtgggt gatgcgacgg acgacgggct gtccctcggt gacgagcgcg
     8401 tacagccggg gatggaggaa ccccacgcgc tcccccagcg cctcgttgag gcggacgatg
     8461 agcgcggccc acatgggcgc cgcggcgctc gtgcccgcgg ccacgccctg ctggcccttg
     8521 aagacgattt gatagccggt gtgcaggtcc gcgttcgcgg cgacgtccgg cacaccccgg
     8581 cccgtgctgc gggagacgga gaacacgccg ttcttccacg acgacatcac caggtccggc
     8641 acgcccatgc cctgctggta cagcggcagc gcgttcatgg tgctgacgcc gccgctgctc
     8701 gctcccgcgg ccgtggagct ggggcccatg gacatcgcct cgcccaggcg gttccacacg
     8761 cgctcgtggt ggaggacgtc ccccaccgcc tccagcgtgg tgccgccaca gcccagcacc
     8821 agcgcgctcg ccgcggggta gctcgtcgcg gccagggtga tggcgcccgt gggcgagtgg
     8881 gcattcaccg gcacctgcga gcccaggtct ccggacgcgg cgcacacggt gatgcccagg
     8941 agcgccgcct cgatgaagag ccgctcgaag gccagctcct cgccctgctg gatgagcgac
     9001 ccttcgtaga aggaccagct ggtggtcagc accgacgggc ggttctcccg gtcgctgatg
     9061 gcctccgcca ggacgcggtg gtagtcgcgc agcgagtagt ccttcgagcc cgcgttgtag
     9121 acgacgacgc gcgcggccgg acacaccgag gccaccagct ccacgtccat ggtgacctcc
     9181 gcgttggagg cggtgttgag cgcccccgcc ttgttcggcc ccacgttcac caccggcgcc
     9241 gtgcgctcca cccccatgga cttcaggtac gcatccaggt ccgactgctt gtagccgccc
     9301 gccagctcga tgatgcccac gcactggcct tccccctggt tgcgggggta gcggtagagg
     9361 ttcgcaacct ggggcgccgt gtacgtgcgc agcccggcct gcttcgccat ctctttgggg
     9421 atgggcaggg ccgccgcgtt gtgggtgacg agcggccgcg tgtccaggcc caggacccac
     9481 tccgccacgc cctccagcgc gcgcggcagg cgcaccggct tcgtgtgcgt caggtaggag
     9541 cgcttcccgt gggtgtagcg ccgcaggtcc acctcgaagg ccttgcgcac cgcggccgtg
     9601 gacccctgga gcacgacgta gccccggtcg cgccgctcgg tggtgacggt gaggccatgg
     9661 ctcttcgcga agcgccgcac ggcggccagg tgcttcgggt tcgtgccgta cttcgcctcg
     9721 aactcgtcgt gggtgagcgg gcggcgcggc gggttcgcgc acaattcctc caccgtgggc
     9781 agcggcgccc cgtgacgcag caacagggtg acctccaccg tgccggtggc ggagcggctc
     9841 cggagcgggg ggtggaggga cgccggggac acacgcgcgc tctgcgtcag ggggatgcgg
     9901 gccatgcgtg gcgttctacc acgcggggtc cgggctcccg gaagccgggg ccggatcgta
     9961 tccacgagcg cgggccccgg ttaggctcgc ccgcctgccc atggaccgag tcctccgcat
    10021 caagccccac ctgcgcgccg aggtgctcga cgcgcggcgc gtgttcctcg tcggagagcg
    10081 cgcccagttc ctgctggagg gggagctgca cgcgagcatc gtgcccctgc tggatggcga
    10141 gcgcaccgtg gagaacgtca tcgccgcgct ggcgggacgg gcctccgcgc cggaggtgct
    10201 ctacgcgctg tcgctcctgg aggagcgcgg gcacgtggag gaagcgcacg acgtcttcga
    10261 tgccagcgtc gccggcttct gggagtcatt gggcgtgggc gcggccaccg cggccgggcg
    10321 gctgttggac gtgtccgtct ccgtgcacgc ggtggacggc gaggacggcg aagggctggc
    10381 ggaggcgctg cgcgacaccg gcctggacgt gtgcgacgcc gccgaccgcc gcgtgctgct
    10441 ggtggacgac tacctgtcgc aggaagcact cgcgctcgcg gaagaggccc ggagcgcggg
    10501 cgccgcgttc ctcccgctga aggtgtccgg caccgcgtgt cacgcgggcc cggtggtggg
    10561 caccggcgag cgcgcctgct ggacgtgtct cacggcgcgg ctgttggaca accgccccat
    10621 cgagaagtac ctcgcgcgca agggcacccc gccgcgcgcc atccgcccgc cgcgcacggg
    10681 cctgcccacc accgcgaagg cagggctgtc cttcgcggcg acgctcgcgg cccgctgggt
    10741 ggtggatggg cccgggcgcc cgggccagac gcggctgtgg acgctggact tcgccacctg
    10801 gaagctggag tcgcacgcgg tggcgcggcg tccgcagtgc ccggattgcg gcgacccgca
    10861 ctggatggag gcccgcgcga agaagcccct ggagctggcc tcgcgctcca agcgcttcac
    10921 cgacgacggg ggccaccgca tcctcacgcc cgagcagacc tgggagcgcc accgccacct
    10981 catcagcccg gtgacaggcg tggtgagcga cctgcgcgcg gtgccgggcg acgcgccgct
    11041 gggccacatc cagtccgcgg tcttccgcgt gtgcccgtgg acggacgcgc cggcctccga
    11101 cgacttccac cgcgtggcca gcggcaaggg ccgcacggag gcccaggccc gagcgggcgc
    11161 gctgtgtgaa gccctggagc gctacagcgc ggtgttccag ggcgacgagc cccgcgtcca
    11221 cgccacggcg tcccagctgg gcgcgcaggc cgtgcacccg gacgcgctcc agcacttcag
    11281 ctccgcgcag ttccagtccc ggcccgaaac cgcgagccgc gacatgcgca ccgcggtgcc
    11341 ccgtccgtac gcggatcaac ccatggactg gagccccgcg tattcgctca cgcacggggt
    11401 ccacaagtac gtgcccacgt cgttcgcgta cctcttcgcg cccccgcccc catctggaga
    11461 cgggccgttc tgcttcttca actccaacgg gaacgcggcg ggcaactgcg tggaggaggc
    11521 catcctccag gggttcctgg agctggtgga gcgcgatgcg gtggcgctct ggtggtacaa
    11581 ccgcctgcgg cgcccgcgcg tggacctgcg ctccttcgac gagccttggt tcgcgtccgt
    11641 gagcgcgcac tatcaatcgc tcggcctcca gctgtccgtg ttggacctta cgcacgacct
    11701 gggcatcccg gtgttcgccg cgctcgtgtg gtcgccggag cgcggccggg cctgggccgg
    11761 gtgcggctgc cacttcgacg cgaagctcgc cgtgcagcgc gcgctcacgg aggtggccca
    11821 gtgctacgac ccgaaggacg tgtcgccgtc gccctgggac gccagcgcgc atggcgacgt
    11881 cagctggctc ttccccaatg acctggtccc cgctcgcgtc cgcgccgact tcccccacat
    11941 gggccacaac gacctgcggg acgacgtgcg cgagtgcgtg acgcgggccg cgagcgtggg
    12001 tctggagacg ctggtggtgg agcaatcacg gcccgacgtg ggcgtatccg cggtgaaggt
    12061 catcgtcccg gggctgcgcc acttctggcc gaggctgggc cctggacggc tgtatgacgt
    12121 ccccgtgcgg atggggtggc tgaaggcccc gaagaccgaa gcgcagctca accccgtgcc
    12181 cttctacttc tgagcgatgg cgccgcctcc tgcccccaag cctcgcatcc tcctggtcca
    12241 gtgcggcccc gaccggcgcc acgtggaccg ggagacggag gacttcgacc cggagcgcgg
    12301 cctggtgaag cgcgcgacga tgacgccgct ggcctgcgcg acgctcgcgg cgctgacgcc
    12361 ggacgccttc accgtggaca tctgggacga ggagctgcac ggccagctgc gcgcggacac
    12421 ggagctgccg gactacgaca tcgtcggcgt gtcggtgatg tactccgccc tcacctacca
    12481 ggcgcgcttc ctgggcgggc acttccgcga ccggggcgcc accgtggtcg cgggcggccc
    12541 cgccatctcc gccgcgccgg aggactaccg gggcttcttc gacgccctct tcgtcaacga
    12601 ggcggagcgc acctggccgc gcttcctcgc ggactggctc gggggcgagt acgcacccga
    12661 gtaccgccag ctcgaaaagc cctcgctgag cgagagcccc ctgccccgct gggacgccat
    12721 cgcggcggac ctcccgcgct acgcgtgggg ctccgtgcag accacgcgcg gctgtccgtt
    12781 cgactgctcc ttctgcgacg tcatctacct gtacggccgc aagcagcggc acaagccggt
    12841 ggagcgcgtg ctggacgagg tgcgggccca tgcggcactc ggagcggagg gcgtcttctt
    12901 cgcggacgac gagttcatcg gcgacgccgc gtacgcgaag gaggtgctcg cggggctggt
    12961 gcccctcaac cgcgccctgc cccgtccgct gcgcttcttc acgcaggtga cgatgaacct
    13021 gagccgcgac gccgcgctcc tggaaggcat ggcggacgcg aacttctaca ccgtcgtcct
    13081 gggcatcgag tccttcgaca cgggcgcgct caaggaagcg cagaagcacc agaacgtgcg
    13141 cgcggacctc gtgggtgacc tgctgcgcat ccaggcgcac ggcatcgggc cccggggcag
    13201 cttcatcgtc gggttcgatc acgacacgcc cgcggtcttc gactcgctgc acgcgaacat
    13261 ccagcgcacg cacctgccct gggtggtggt ggcgcccctc caggccccgc gcggcacgaa
    13321 gctgtggacg cggctgcgcg cggaaggccg gctcgccacg cctcgccggg cgcacgcgaa
    13381 ggaccggggc gccatcgtgc tcaacgtgat gcccctgggc atgacgcggc cccagctgct
    13441 cgaaggcttc cgcgacctgg tggagcggct gtccacctgg gacgccgcct gcgagcgcat
    13501 ccggggtttc atcgccggca tccagcgccc gccccaggta gaggagcccc actggccgga
    13561 ggccgtcacc gaccgcttcc tgcgcgaggc caccgccgcc tgggccctga cgccgtccga
    13621 gcgccacgcc ctgggggaca cgctcgccca ggtgcgccgc accgccccgg cgatgctgcc
    13681 gcgcgcggtg ttcttcctcg cgcgcaacca gaacgagcgc cgccgccatg agcgcctctt
    13741 cacggacttc gacgcggtgc tggccgccga gcgacagggg gacctcgtcc cggacaccca
    13801 gcccgtctac gtcccgccgg gcttcgccac cgcgatgcgc gacgtgttcc cggacctctt
    13861 cgtgcgcctg agccgcgacc tgccggaccg ccgcgacgtg ccggaggctt cacgcgacgt
    13921 gctggtggac ttcgtcgccc gctggggcga aggcttccag gcgctccagc cgcagcacca
    13981 cgaattcctg cgcgagttgt gcgaccgtga ggtggcggcg cgcggtggcc atccaggcac
    14041 gctggaggtc gtggaggagc aggccctgcg cacccaggcg cgccgcaccg gcctgctgga
    14101 agcactgctc aaggacgtgc gcgacgagct cgcgagctgg ggaccctgac gcatgcgcga
    14161 cggccttcac atcttcgacg cggaccggca cgtcctggag ccgctgagcc tgtgggcgga
    14221 gcagctggag cccggcctgc gccggcacgc gccccgcccg ggacgcctcc cggacgaaac
    14281 gctggaggag cgcctggagc ggctgggccc ccagggcctc ctgcccgtgc tgcccctgcc
    14341 ggaagtggac ggcaagccgc tgtggaacca catgccggag aaggcctggc tggcgttctc
    14401 cgagcgctcc tacgcgcagc tggggcgcaa tgagttgctg cagcggccag acgtgtacct
    14461 ggcccagatg gatcgcgacg gcgtggacat ggcggcgctc ttccccacct acgcgctgct
    14521 cctggagggc ttctcgcccc tcgaacccca cgtcgccact gcgttcgcgt ccgtctacaa
    14581 cacctggctg cacggcttct gcgcgcacca gccggagcgc ctgcgaggcg tggggctcat
    14641 cagccggcac cagccggagg ccatggtcgc cgaggtccgc cgcgtcgcgg gcttcggctg
    14701 gcgcgccgtc atggtgcgcc ccaaccccat cggcggccgc ctgctgtcgg acgccgccta
    14761 cgagcccttc tggtccgagt gcgagaagct ctcactcgcg gtcgttctcc acggcagcgg
    14821 ccacgtctac gtgccgtccg cgggcgcgga ccgcttcgac acccgcttcg ccaaccacgt
    14881 gtgcgcccac cccatggagc tgatgatggg gctgctcgcg ctcctccagg ggggcgtgct
    14941 ggagcggcac ccggccctgc gcattggcgc catggaggcc ggctgcgggt ggctcccgta
    15001 ctgggcgtgg cgtttggatg aggaatatcg cgctgtgggt gcagaggtct ccgccaccat
    15061 ccgacagctc ccttcagcgt acctgcgcca gcactgcttc gtttccgtgg aaccggacga
    15121 gccgtacctg cctgacgtgg tgcgccacct cccggaggac cgattggtat tcggaagcga
    15181 cttcccccat ctcgaccacg gcgaggatgt gctgggtgcg atgctgtcct tgcgtgacgt
    15241 gatgaccgaa agtcgtctac gaaaggttct ctgggaaaac ccgactcggt tctacggtgt
    15301 ggaaccgtga ggccgcacga atgagattgt cgctcgccga aggtgtggcg ctgcgttgcc
    15361 ccgacgcgga ggacgcgcgc gtggagggcc ctggccgctc actgcggttg ggcccgctgg
    15421 cccccggtgt gcgcgccgtc ttcgagtcgc tcgcggacgg aggcatccac gagacggagg
    15481 tgccggccgc cgcgggctcg gacacgacgc tcgcgtggta ctggctggac ctggcgggag
    15541 acggcggcct gctgtcgtgg acggtggagg agcgcggcaa cctgctcctg acgctcacgc
    15601 ccgcgtccgc gtccttcctg cgccaccgcg cgacattcga cgcgtcccaa ccgctgcagc
    15661 tgtcgcgctt cgcgcacacg cgcatggcgg agggccgcgc ggtgctggac tgccccacgg
    15721 tgcacgccac cgcggcgctg catgaccggc gcgtggtgtc gctgctcttc gacatggccc
    15781 gccccacgct gctggcgcgg ctcaaccagt tcaacaccgg catcgagtcc ttcacgctgc
    15841 gcgagctggt gcgcctgctg gcggagacgg gcatcctggt ccccaacggg ctggacgtgc
    15901 cggcgtcgga ggagacgcag acggcgctca agcagtggga gccgcacgac ctgctcttcc
    15961 acctgcgctc gcgaggctgg ggccaccaga cgcgcgcggg ggccacctac cgcttccggg
    16021 gcgagctgcc caacccgccc gccctcaagc ccaccgtgac cgaggaggtc gtggagctgc
    16081 accggccgga cctggaggcg ctgcgcgcgg gcggcgaccg ctccttcacg gaggtgctgg
    16141 aggcccgccg cagcctgcga ggccggggcg cctcaccgct caacgtgaag cagctgggcg
    16201 aactgctcta ccgcgccgcg cgcgtgcgcg ccgtgcgcac cacgcaggac ggcgaaatca
    16261 ccgaccggcc ctatcccggc gcgggcgcgg tgtacgcact ggagctctac cccatggtgg
    16321 gcgagtgcca gggcctgccc ccgggcgcct accactacga tccgctgggc caccggctgg
    16381 agaagctgag cggccccacc ccggagttcc acgcgctcct ggatgaagcc cgcgcaccgg
    16441 cggagccctt cgagcggccg gaggtgttga tggtggtggc cgcgcgcgtg ccccggctcg
    16501 cgtggaagta cgagacgctg gcgtactcac tggtgctgca ggacacggga gcgctggtcc
    16561 agacgctcta cctggtgtcc accgcgatgg ggctgcggcc ctacgcgctg ggccggagcg
    16621 atccggactt cttccagcgc gtggcgggcg tggacggctt cggcgaggcc agcgtgggcg
    16681 ccttcgcggt gtcgggaggc gagtctccgg accgctagag cgcccttcgc gacgctttag
    16741 cagcaggggc tgccgcagca atgcgagcgg ccgtgggtgt cggtgaggct ggagagcgcc
    16801 acggcgtggt ccgccacgtc ggcgggcttc ttcggcaggt gcagctccac ctccgcgctg
    16861 ttcaccttcc aggtcccgtc cgccgccgcg tccttcacgc tggaggggac gaccttcagc
    16921 tggatgctgg cgggcaggtc gaagtcgaag cgcttcttga gggcctggcg cgggtccttc
    16981 tggagggccg cctcgaactc gggctccttc cacgccagcg cgacggcgcg catccacacg
    17041 gcctgccagt cattcaccga ggccttggcc tccgggcctc gcgtgggctt gcgcgccacc
    17101 ggacgggccc gtgcgggcgc ggccttcgac tccggcttct tcttgctcat gtcagcgttc
    17161 tcctcccagc gcatccaaca acgcgcgggc ctccgagacg ggtggtgtcc cccatccttc
    17221 ggagaaggta ctgtagaccg tttgcagccg ttgccgggct tcttcctgtc gcccggatgc
    17281 ctggagcacc cgcgccaggg cggtgacggc ctgcagctcc cgcatccgcg cgccctgtgc
    17341 gtgtgccacc tccgccgcct gccggaagca ggtctccgcg gagagtgcag tgtttccatc
    17401 ccgctgcagc agcacccggc ccttgacgtg cagcatcttg gactcgtggt acgcctcgcc
    17461 cagggcctgc gcgcgctgct ggccgcgctc cacggaggcg agcgccgcct ccacgtggcc
    17521 cagctccagc tccagctccg cgagcatggc gtagtacgcc ggctggtcca tctccgtgcc
    17581 gaatgcctcg cgcagcgcga tgccgcgccg catcgcctcc aggtccttca cggcccaggc
    17641 gcgcaggatg cccacatagg cggcctgctc cagcaggccg tagcggtggg acagctccga
    17701 gtgctgggag atgagctgga gcgcctccgt ccggtcgccg tgctcctggg caatcagcag
    17761 caggtagatg aacgacaggc cgatgctggt gccgtggttc agctcgcggc cccacgccac
    17821 cgcggcctcg ccgtgcgcct tcgcctggtc cgggaagccc aagagccact tcccccggca
    17881 cagcacggac tcgccgccca cgcgcgtgtc ctgtccgtag aggatgcggt gcatccggtg
    17941 cgcgaccggg tcgaacaacg acaggcaccg gtccgccttc gccttcgcct cgcccaggcg
    18001 gccttccagc agctcgatgt tggagaggat ggtgagcgcc accgcctcct ggcccgcgtc
    18061 cccgcttcgc tgcgccagcg ccaccaggcg gtccagcaag ccgcgcacgc ggcgctggtc
    18121 acctcccagg tggtagaaga tggagaggac ccacagcgtc ggggccgcgt aggggctctc
    18181 ccccaccgtg aagagcagct ccagcgaacg ctcggccacg ttgcgcaggt cctgggagcg
    18241 ccagccctgc gtggacatca gcgccggcgc gagcacgccg ttgaggctca gctccagctg
    18301 cgcgcgctcc accgggtcgt cgatggcgtc cagccacgac aggcccagcc gggcgaagag
    18361 gatggcctcc aggtaggcgg agcgcaccag cgcggcgaac gcggccttct gcgcgtagag
    18421 gatggccttg cgcttcaggt tcgcggcggc ccagtggtgc gcgagcagat ccggccgcga
    18481 ctccacctgt tcctggaagt gcgcctccat cgcctccgcc gtcttcgcgt gcatctgctg
    18541 gcggtaccgc ttgagcatgg agtcgtaggc cgcgtcccgc accagcgcgt gcttgaagag
    18601 gtacacgggc cccttcggcc ggcgcttgcg gtgcaggagc cccgagccca ccagccgctc
    18661 caaatccgcc tccagcgcct cgggcgtcag cgggctcacg tggcgcagga gctcatgcgt
    18721 cagctcacgg cccagcacgg aggcgatctg cgcggtctcc ttggcgcggc ccagccggtc
    18781 cagacgggcg acgagcaaat cgcgcagcgt gcccggcacc gaggggcccg ccttgctggc
    18841 ctcgagcgcg aagcggccct cgcgctccac cagcgcaccg gactcgcgca gcgtgcgcac
    18901 cagctcctcc acgaacagcg ggatgccgtc cgtgcgcgtg gaaatctcct ccagcgcctc
    18961 cggcgagagc gggcctcccg cggcggcggt ggccaggcgc tccacctccg cgcgagccag
    19021 cgcgcccagt tgcacctgcg tcaccgccga cgcggcccag ggcggctcca gctccggccg
    19081 cgcgctgaac acggcgagca ggcgcgacga ggacacctcc tccaccagcg ccttgagcag
    19141 ctccagcgtg gaagggtccg cccagtgcag gtcctccagc gccagcacca cgggctgccg
    19201 ctccgccatc gcggcgagga acgcgagcag cgcgttgcgc gtgagctccc ggtgcttcaa
    19261 gggcgacacg tccagcggcg cccagcgctc cggcggcagc ggcagggaca agagcgacgc
    19321 gaacaggggc agcgtctccg gcagctcgaa gctgtagccg gacaagagcg cctccaggcc
    19381 cgtcagccgg ccctccggcg gcaggtcgcg gttcgggtcc agcatccgcg tgagcaggtc
    19441 caccacgggg gcatacgcct ggccggagct gtcctccgtg cagcgcgcct ccagccacgt
    19501 gtggggctcc gcgcccagcc ggtcccccag ctcgcgcatg aggcgcgact tgccaatgcc
    19561 cggctcgccc gaaatcagca ccacctgccc ctgccccgag cgcgcctgct cccagcgcga
    19621 cagcaccagg tccagctcgc gcgtgcggcc caccagcgac agcgcttcgt cggtgccgct
    19681 ccacgtcgcg tccgcgccct ggagcacgaa cgtctccagg cccgggggca acagctcgtt
    19741 cggcgacgcg ggcgtgggct ccaacgggaa gtgcttgcgc accagctgct gcgtgtcgcc
    19801 cgtgacgagg atggcgcccg agggcgcgga ggtggacagc cggaaggcaa gcttcggcgt
    19861 ggtgcccacc acgaagccca ggccggagag cgtggggtct cgctgctcgc gcgacaccac
    19921 caggcccgtg tgcaggccca cgcggatctc cacccgcgtg ccgcgctcgg cctcgatggc
    19981 acggccgcgc cgcttcacct ccgccaccat gtccagcgcc gcctgcgccg cgcgccgcgc
    20041 atcgtcttcc cgagccgccg gatagccgaa gtagaagagg acgatgtcgc ccagcgcgct
    20101 ggcgatgtgg ccgttgtagc gccgggcaat ctcgatgcag acctcctgct gggcacccag
    20161 cacgtgatcc agctcctcga tgtccaccgg ccccggcgcc gtctgcgtgg cggacagcgt
    20221 gcagcacacc accgtcagct ggcggcgctc gccctccgcc caccggcgcg agcgcgtgga
    20281 cacggcgttg ggcgtgcggc tggacagctc caccgtcgcc gtctccgcgt tgggagcggc
    20341 gggctggatg cgcacgggcg cgggccggcg cggcaggttg gacacgtcca ccgcctccag
    20401 ctggcgcagc agcacctccg cggacacggt gcgctgggac gggtccttcg cggtgacgcg
    20461 ctggagcagc ttgcccagcg ggtgcgcggc gatggccgac ggaatgggca ccggctccga
    20521 ggagagctgc tggaagatga cctccgcgac ggtggcaccc tcgaagacgc ggcggccggt
    20581 gaggcactcc aggaacacca gcccccacgc gtacaggtcc gagcgcggcg tgggcgcctg
    20641 cccgcgaagc tgctccggcg ccgcgtatga cggcgtgccc agcgactcat tggtggacgt
    20701 gatgcgcggc tgcgcttccg tgcgcgtcag ctcgtccgtc accgacccga tgccgaagtc
    20761 cagcaccagc gcgttgcgac gggcgccggt gggcacgacc atgatgttcg cgggcttcag
    20821 gtcgcggtgc accacgttct gcgcgtgcgc gcacgccagg gcgtccaaga gctggagcat
    20881 caggtggcgc gcctccaccg gatccagcac gccctcctcc gcgagcacct gcgccaggtt
    20941 cttccccggc acgaactcga agatggagta gacggcgccg ccctgcgcgc gacccgagtc
    21001 gatgagccgc acgatgttcg ggtggtgcat ctgcgcgcac agcttcatct cgcgctcgaa
    21061 gcgcgcgctg cggcgctcca cggactctgg agtcgcgccg tccgtcaggc gcaggagctt
    21121 caccgccacg ttctggccgg tggtcacctg gcgggccttg tagacgcggc cgaagccgcc
    21181 ctcgcccaat tccgacagga gctcgtaccg gccctggaag gcttccaaca gctggggatc
    21241 catggggttc ttcatcgcgt tcccgagcct cgctccattg atgaccgtcc cccccgcctg
    21301 ggcagggtga tgacgaactc cgtgaactca cctggcaccg tctccatgcg gaacgtgccc
    21361 tggtggccct gcacgatgat gtcatggctg agcgacagcc ccagccccgt cccctgcccc
    21421 ggcggcttcg tggtgaagaa ggggtcgaag attcttcccg cgctctccgc ggggatgccc
    21481 ggcccgttgt cgcgcagccg gacctccacc tgctctggac gcgcgagggt gcgaaccttg
    21541 agcaccggca cgtacgcggc gccctgcgcc tggcgcttct gacgcatggc gtagagcgcg
    21601 ttgtccacga cgttgatgat gacgcggccc acgtccgcgc ggctgagctc cagccgctcc
    21661 acggccgggt cgtactcggc ctccaggcgg acggtcaggg gctcgcctcg catgccaccc
    21721 tgccccagcg cgacgctctc cgcgaccagc gcgttcagct ccaccgcttc gcgcgggccg
    21781 ggcgagcggc gcgcgtgctg gagcatgttc tggatgagcg cgtccgcgcg gcggccgtgc
    21841 tcgttgatct tctgcacgtt ggtgcgcagg cacgcgagcg cctcatccac gtcgcgcacg
    21901 gagtccgccg tcagccgttc gcgctgcggc tccagcactc cggccaggtc ctccgtgagg
    21961 cccacggaga ggccggcgaa gttgctgatg aagttgagcg ggttgcgcag ctcgtgcgcc
    22021 atgccgccca ccagcgccgc gagcgaggcc agcttcgcgt ccatgatgag ctgcatgcgc
    22081 tgcaccgtct cctgctcgat gcggcggtag agcctcgcgt tctccagcgc gagcgccgcc
    22141 tgccccgcga acgcgacgag gaactccagg tcgtcctcgg agaagctctt gggcgtggag
    22201 acattgtcca cgtagagcac gcccagcacc tcgtcgcggg gcttgagcgg cacgcacatg
    22261 gaggcgcgga tggagctgaa gatgacggac tccgcggcgc ccaggcgcgg gtcattcacc
    22321 gcgtcggaga agagcgccgc cacgctccgg cgcagcacga agtccacgat gttctggctg
    22381 tagatgggtc cgcgcacggc cgtgccctcg gccgtcttcg tcacgcgcgg ctccagcttc
    22441 ccggtgccct cgtccaccag caggatggcg ccccgctcca cgtggaggat ttgaaacgcc
    22501 aggtccaaca ccctgccggg cagcgcctcc aggtcgtccg tgacggacaa cagcttcgcc
    22561 acctcctgga ggatgcgcat ccgctcgcgg gcgcgcgtgg cggtgccggg ggcctcctcc
    22621 gcggacttct ccgagccgga caccgcctgc accagcgtct tcagcggcac gcgggtgagc
    22681 gcgcgcgtga gctgggggcg gggttcgccg gaggcaccgg atgccgagcc ggagccgggc
    22741 gggcccgcgg gcacggccgg tggcgcttcg tgggtgagca ggaagacgag ctcgcccagg
    22801 gtcagcgtgt cgccggggcg cagctccttg cggcggatct gcacgccgtt gacgaaggtg
    22861 ccgttcttgc tctggaggtc ggtgacgaag aagcgcccgt cggagggctc gatgcgggcg
    22921 tgctggcgcg acaggctgcg gtggggaatg cagatgccct ggtcgtccgc gcggccaatg
    22981 gtgatgggcg cgtcccccag cgggtaggac agctcatccg gctgccctgg gttgtagacg
    23041 agcatcggca cggccttcgg accccctcca gggtcgcaag cctagccgaa aagcgacggc
    23101 cagaaccggc ccggccgtct caggcggcgc tcgcggccgg agccaggagc ccccggtccc
    23161 gcagcgtgtc gaggatgcgc tccacccccg cctccaccgt ctccgcgtcg gagcggacgg
    23221 tgatttcggg ggattcgggc ggctcgtacg ggtccgacac gccggtgaag tggggaatct
    23281 ccccggccag ggccttcttg tagagcccct tcacgtcccg ggcgatgagc gcgtccaggc
    23341 tggcctggac gtagcattcc aggaacggga tgccggcctg ggtggccagg gcgcgcacct
    23401 cgtcccggga gctcttgtac ggcgagatgg cggcggtgat gacgcccacc tcgtgcttgg
    23461 ccagcacgcg cgccacgtag ccgatgcgcc ggacgttctc ctcgcggtca gcgcggctga
    23521 agcccaggcc gcgggagagg tacgtgcgca cctcgtcccc gtccagcagc tccacgcgct
    23581 gcacgggcga cagctgccgc gccaccgcgg tggacagcgt gctcttgccc gcgccggaca
    23641 tgccggtgaa ccagaggatg aagcccggac gctgttgcat cgccattccc ttacctgtcc
    23701 acggcggggc cgttgatcat ccccgcgccc acggtggcgt tggtgccttc atccacgagg
    23761 atgaagctgc cggtgctgcg gttgcgccgg tactcgtcga agaagagcgg caccgtcgtg
    23821 cgcagcgtca cccggcccac ctcgttgagc ttcaagccgg agctctgctc gtcgcggtgc
    23881 agggtgttga cgtccagccg gtagtgaagg ttcttcacca tggcgcgcgc catgcgggtg
    23941 gtgtgcttga tggccagacg cgagccgctg ttgagctgcg tggagtccga cagccagcac
    24001 accatcgcgt cgatgtcctg gctcgcggtg ggcgggttgc ccgggcggca cagcatgtcg
    24061 ccgcggctga tgtccagctc ctcctccagc gacacgttca ccgacatggg cgggaacgct
    24121 tccttcagcg gcttgccggc cagctccagc gacttgatgc gcgtggtgaa gccggacggc
    24181 atcaccatca cctcgtcgcc cggacgcatc acgccgccca gcagctgccc ggagtacgcg
    24241 cggtagtcgt ggaacttctt cgcggacgcg ggccggatga cgccctgcac ggggaagcgc
    24301 aggtggatga ggtcccggtc agacgcgatg tgcacgttct ccaggtggtg caggagcgtg
    24361 gggccctggt accaggccat cttctccgag cgcgtcacca cgttgtcccc gcccagcgcg
    24421 gagatgggga tgaacgacag gtcggacacg tccagcttca tggagaactg gcggaactcc
    24481 tcccggatgc ggtcgaacac gccctggtcg tagtccacca ggtccatctt gttcacgcac
    24541 agcaccaggt gcggcacgcg caggagcgac gcgatgaacg cgtggcgccg cgtctgctcc
    24601 agcacgccct tgcgcgcgtc caccaggatg agcgccaggt ccgccgtgga cgcacccgtc
    24661 accatgttgc gcgtgtactg caggtgtccg ggcgtgtccg cgatgatgaa cttgcgcttc
    24721 gccgtggaga agtagcggta cgccacgtcg atggtgatgc cctgctcgcg ctcggccttc
    24781 aggccgtcca ggagcagcgc caggttgacg tactcgtcgc cccgggcgtg gctcgtgcgc
    24841 tccaccgcgg cgagctggtc ctcgaggatg gacttcgtgt cgtacaacag ccgcccgatg
    24901 agggtgctct tgccgtcatc cacggagccc gcggtcgcga atctcagcag ttccactaga
    24961 agtatccctc gcgcttgcgg tcttccatcg ccgtctcaga gaacttgtcg tccgcgcggc
    25021 tggcgccacg ctccgtcacg cgggaggccg tcacctccgc gatgacctgc tccaccgtgg
    25081 acgcggtgga cggcacgcac gcggtgcacg tcatgtcgcc cacggtgcgg aagcgcaccg
    25141 tctccgtcgt caccgtctcg ccgggcatca tggacatgaa gggcgaccag gccatcagca
    25201 tcccgtcccg gcggaacacc tcgcgccggt gcgtgtagta gatggacggc agcgccacgt
    25261 tctcccggcc gatgtactgc cagatgtcca gctcggtcca gttggacagg gggaacacgc
    25321 gcaggtgctc accgcggcgg tggcggccgt tgtacagcgc ccacaattcc ggccgctggt
    25381 tcttcggatc ccactggccg aactcgtcgc ggaaggaata cacgcgctcc ttcgcgcggg
    25441 ccttctcctc gtctcgccgg gccccgccga agacggcgtt gaagccgttc ttctcgatgg
    25501 cctccagcaa gggctgcgtc tgcaggcggt tgcgggacgc gcgaggaccc ttctcctccg
    25561 tgaccttgcc cgcgtcgatg gcctcctgca cggacgcgac gatgagccgc gcgcccagtt
    25621 ccgccacccg ttcatcgcga tactggatga cctccgggaa gttgtgcccc gtgtccacgt
    25681 gcatcagcgg aaacggcagc ggtgcgggcc agaaggcctt caccgccagg tgcaacatca
    25741 ccgcggagtc cttcccaccg gagaagagca gcaccggccg gtccagctcc gccgcgactt
    25801 cccggatgat gaagatggac tcggcttcca gcgcctcaag atgtgaaagc tcgtagctca
    25861 cggacaggca agctaccaca accggtccca cgcccaaccg tggccgtgaa ggtttccgct
    25921 tccgcgagtg tgagacacgg cggatgtgac atgccggagg gggcggtgaa acatcgccgg
    25981 aggacctgct gggagggatg tttcacggcc cactccgggt gcgtgcttcg ggcccccacc
    26041 cgccgtgcgg gaggcggttt ccgcgcgggg ggcgcgtggt atagacggcc gcgccatggc
    26101 aagcgcatcc cctcccgtcc tcgaccgttg gttcccgtcc cgcaagccgc tcccggagcc
    26161 gcgcctgcgc ctgttctgcc tgccgttcgc cggcgggagc gcggccatct accagccctg
    26221 gagcatggcg ctgcccacgg gcgtggagct gtgcgcggtg cagctgcccg ggcgcgagcg
    26281 gcgtctgatg gagcccgcga tgaagtccct gccggagctg ctggacgtgc tgatgccggc
    26341 gctgacgccg ctgatggacc ggcccttcgc gctgttcggc tacagcatgg gggcgcgcat
    26401 cggcctggag gtggcccgga cgctgaagcg ccagggcggc ccgaagccgc tgggcttcat
    26461 cgccgcggca gcgcccccgc cgtcgcacaa cgaccgggag cccatccaca cgctggatga
    26521 tccgggcttc atcgcgaagc tgcgcgagta cgacggcacg ccggaggagg tcctccagca
    26581 caaggagctg ctggagctca tcctccccac gctgcgcgcg gacttctcgc tggcctggtc
    26641 ggagaatggc aaggacacgg ccccgctgga catcccgctg tccgtgtacg cgggcaaggg
    26701 ggacaagcac gtggggtt
//
