LOCUS       NC_017030              10873 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Corallococcus coralloides DSM 2259, complete sequence.
ACCESSION   NC_017030
VERSION     NC_017030.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus coralloides DSM 2259
  ORGANISM  Corallococcus coralloides DSM 2259
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Kneip,S., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Complete genome sequence of the fruiting myxobacterium Corallococcus
            coralloides DSM 2259
  JOURNAL   J Bacteriol 194 (11), 3012-3013 (2012)
   PUBMED   22582372
REFERENCE   2  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2012) Ecophysiology, Max Planck Institute for
            Terrestrial Microbiology, Karl-von-Frisch Strasse 10, Marburg, Hesse
            35043, Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method :: Newbler v. 8/10/2010; Celera v. 8/10/2010
            Coverage                          :: 42-fold
            Sequencing Technology             :: Sanger dideoxy sequencing; 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000255295.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:27:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,155
            CDSs (total)                      :: 8,082
            Genes (coding)                    :: 8,042
            CDSs (with protein)               :: 8,042
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 11 of 40
            Pseudo Genes (incomplete)         :: 26 of 40
            Pseudo Genes (internal stop)      :: 6 of 40
            Pseudo Genes (multiple problems)  :: 3 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5680011
            Orig. end                         :: 5690884
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003389.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="24"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10873
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5873](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     tRNA            complement(34..107)
                     /anticodon=(pos:complement(5680082..5680084),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="COCOR_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="COCOR_04478"
                     /product="tRNA-Met"
     gene            complement(34..107)
                     /locus_tag="COCOR_RS22370"
                     /old_locus_tag="COCOR_04478"
     misc_feature    130..144
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.96"
                     /tool="antismash"
     tRNA            complement(186..259)
                     /anticodon=(pos:complement(5680234..5680236),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="COCOR_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="COCOR_04479"
                     /product="tRNA-Met"
     gene            complement(186..259)
                     /locus_tag="COCOR_RS22375"
                     /old_locus_tag="COCOR_04479"
     gene            complement(363..2381)
                     /locus_tag="COCOR_RS22380"
                     /old_locus_tag="COCOR_04480"
     CDS             complement(363..2381)
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020480719.1"
                     /locus_tag="COCOR_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04480"
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="WP_014397285.1"
                     /transl_table=11
                     /translation="MSDEKSGGNSGGPGGFGPKKPKATFGDVMLGIPSGGQGNERGGGR
                     GGRDEKSGPGRGDRGPRDAQSQPRPQGDAPRGGGERGGGRGGERRGGSGGGGGGERRPS
                     GPMVVVKRASGSIETRALEGEKPAEATATAEQTGADAQASAASTPAPAPRPVTPAPAPS
                     SPLYDEVPETESFADMFEAQVKDGGAPGRRGVRIGEKVAGTIFQLGADTAFVSLDGSAK
                     SEAMIELRELKDDEGILRFGVGDRLEAHVVEMGARGIQLSRALAKGNASFAMLAEARAS
                     GMPVEGLVLSVNKGGVEVAIGETRAFCPISQLDIRFVEKPDQFIGEKLQFRVTEVRDRN
                     VVLSRRSLLEDEQRRLATETRKNLAVGKTVKGKVSGVRDFGVFVDLGGVEGMVPVSELS
                     YTRVAHPSDVVKQGDEVEVEILRMEEGQPNSPDKSKQKERITLSLRSRQEDPFKKALEE
                     IKEGDRMQGKVVRLQPFGAFVELRPGVDGLVHISALSDRRIAHPRDAVKEGEVIWVSVE
                     KIDPNDKRIGLRRISEEEAQRPPEERPAKEAQAPSAPKEPAAPRPKVGAVVVGKVDRLE
                     PYGVFLAFPGGKGLIPASETGTDRGTDMRKHFSIGQELKVAIIDIDASGKIRLSIPAAI
                     RAEERAEVEAWQKTQQPVGGGKKGFGTFADLLSKLGK"
     gene            complement(2610..4343)
                     /gene="murJ"
                     /locus_tag="COCOR_RS22385"
                     /old_locus_tag="COCOR_04481"
     CDS             complement(2610..4343)
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940155.1"
                     /locus_tag="COCOR_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04481"
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_083892158.1"
                     /transl_table=11
                     /translation="MTAPAPASPPSAGSPAAPLPSSPERSAGGRGAMLVGIGILASRLM
                     GLVRERVFAHYLGNAEAAAVFKAALRIPNFLQNLFGEGVLSGSFIPVYAQLLGKKDADE
                     ADRVAGAVFGLLAMATAVMVALGMLATPLFVDLIAPGFEGGERDLAVRLVRILFPGTGF
                     LVLSAWCLGILNSHRRFLLSYLAPVVWNVVIIATLLVVGSLHGTAGGRAAEEAVTEWLA
                     YGVVLGSFLQFAVQVPTVMRLLGHFRPVVSLASASVRQVLKNFGPVVLGRGVVQFSAWV
                     DTAFASLISNRALSSLLYAQTIYLIPVSLFGMAVSAAELPEMARATAEGEAQAHTKLRS
                     RIDAGSRRIAFWVVPSAVALFFLGDLVSGALLQTGRFGASDSRYLWYLLMGAAVGLVAS
                     TVGRLYASAFYALKDPKTPLRYAIVRVSLGSVKAWFLALWLPERLGLPRELGAAFLTLS
                     SGIVAWVETTLLRRKLRSIVGPVGPPSGLLPRLYVAAVVGGLVALTVKQGLTGLLGPMP
                     GVGAEWGGTLLVPPRLHPVLGLLATAVPFGLVYFAVSAALGVPEAGAVFRKVGRKLRLV
                     R"
     gene            4449..4937
                     /locus_tag="COCOR_RS22390"
                     /old_locus_tag="COCOR_04482"
     CDS             4449..4937
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940154.1"
                     /locus_tag="COCOR_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04482"
                     /product="ferritin family protein"
                     /protein_id="WP_014397287.1"
                     /transl_table=11
                     /translation="MAGKSDTERSDVARIRAVLARELETINEYEAFAEDSSNPEVKAFF
                     LHLAAEEKEHVSEATHMLRMLDKGQDAHFAKPFVPGHFQAAVGSVPSEPALPAAEPVHA
                     APPAPPAVGRLANEPLTSLPPQRLIYGVPAPPPSANGHPLTIGSLRRGGGSGGSGGGR"
     gene            5001..5873
                     /gene="encA"
                     /locus_tag="COCOR_RS22395"
                     /old_locus_tag="COCOR_04483"
     CDS             5001..5873
                     /codon_start=1
                     /gene="encA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002640634.1"
                     /locus_tag="COCOR_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04483"
                     /product="encapsulin nanocompartment shell protein EncA"
                     /protein_id="WP_014397288.1"
                     /sec_met_domain="Linocin_M18 (E-value: 5.7e-83, bitscore:
                     276.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDFLGHAENPLREEEWARLNETVIQVARRSLVGRRILDIYGPLG
                     AGVQTVAYDEFQGVSPGAVDIVGEQETAMVFTDVRKFKTIPIIYKDFLLHWRDIEAART
                     HNMPLDVSAAAGAAALCAQQEDELIFYGDQRLGYEGLMTANGRLTATLGDWTAPGGGFQ
                     TIVEATRKLNEAGHFGPYAVVLSPRLYSQLHRIYEKTGVLEIQTISQLAADGVYQSNRL
                     RGESGVVVSTGRENMDLAVAMDMVAAYLGASKMNHPFRVLESLLLRIKHPDAICTLEGA
                     VPAAPPARR"
     gene            5899..7323
                     /locus_tag="COCOR_RS22400"
                     /old_locus_tag="COCOR_04484"
     CDS             5899..7323
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013940152.1"
                     /locus_tag="COCOR_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04484"
                     /product="sigma-54 dependent transcriptional regulator"
                     /protein_id="WP_014397289.1"
                     /transl_table=11
                     /translation="MAKVLVIDDETNLRKVLAALLRRDGFDVTVAENGEQGLAEFHKNG
                     ADIVVTDLVMPKLGGMEVLAAVRAANPDVPVIIITAHGTVDSAVEAIKAGAFDYITKPF
                     DQAELSSVVAKAAKTNESAKRSVRADHKARSAIIGESPQIQDVYKIIDKVADTPSTVLI
                     TGESGTGKELIATALHGASSRRDKPFIKINCAAIPATLLESELFGYEKGAFTGAVTSKP
                     GRFELADEGTLFLDEIGEIPVEMQVKLLRALQEGEFERVGGIKTTRVNVRLVAATNRDL
                     QAEIEAGRFRKDLYYRLAVVPIVLPALRERRGDIPMLAAHFVDKYNRRLHKKIEGIADD
                     ALALLQAYAWPGNIRELENLIERVLLFADGPLITAKDLPEPVRGGAGVQAGAQVAASLG
                     TLDVPVGEVGLKDIVRMKAAELERDLIVKKLEETGGNVTRAARLLQISRKSLQTKMKEF
                     GLRDTTPDGQEDGPDE"
     gene            7400..8431
                     /locus_tag="COCOR_RS22405"
                     /old_locus_tag="COCOR_04485"
     CDS             7400..8431
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015349973.1"
                     /locus_tag="COCOR_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04485"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_014397290.1"
                     /transl_table=11
                     /translation="MRPNLPTLGGPPKRNPFGPVVAVSVILGAAAGGVWWWKQRMADVP
                     MDVASQTASALDAGTVAQAPVAPPAPTDPVKAAGLERVSIRIEGPLETALVQASDATVG
                     PALAQVVTRTLVWWVRVPGEILRGDTLDVLFQRRPNEEPLVYAVRFVSGKTGQTHRAYR
                     FTPAGEANARYYLPGGDELELRMEKSPIDSYEQITSLLRDGRGHKGVDFRAPVGTTVRA
                     PFAGVIKRKNWNFGSNGNCIELVETGGKGRRALFLHLAELPKNIQAGMRVNAGQVLAQS
                     GNTGHSFAPHLHYQLMLGENRVLDPFDQHKTFRASLAAAHKGAFDTEVQRLDGLLGTSV
                     AGK"
     gene            8510..9796
                     /locus_tag="COCOR_RS22410"
                     /old_locus_tag="COCOR_04486"
     CDS             8510..9796
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011553582.1"
                     /locus_tag="COCOR_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04486"
                     /product="hypothetical protein"
                     /protein_id="WP_014397291.1"
                     /transl_table=11
                     /translation="MHRFRAVIAALTLGVPFAASAAEITRIASSFEDDDPFDLFLDVGF
                     ERTQTRAKIVREQLRGGDATDVSEVNELWYKGTDARLNLAVAFGLWKDLEFSFKLPIVF
                     QQNETWNFVSGTNQGNSTITNSCYNADGSPYSAEGCVGRLFQVPQESYRGGLGNVHFGL
                     AYAFFNQEKDDTKPTWIVGIDYEAPTAKQRDPSLNNTDPDGDRGNVGDRVHKYQLYTTF
                     SRKMGVAEPYFKASHTIPVRGPGAYSNCDQSSLPYPGNLGAPYNCYKEPWTRHETGIKA
                     PSQTALTFGMELVPFENAARSQKFALDVRLLGNYVGRGRYYNELTSALRKLLTSDDYFQ
                     VGGQVGVTARAAQAFTIRASGNFLYNTDHLLTSEAIGQDLNGDGQVDTAVGSPELNPTF
                     DWRYDLVSRRFRAIQSTTFRFDLGATFSF"
     gene            complement(9827..10660)
                     /gene="rsmI"
                     /locus_tag="COCOR_RS22415"
                     /old_locus_tag="COCOR_04487"
     CDS             complement(9827..10660)
                     /EC_number="2.1.1.198"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002625294.1"
                     /locus_tag="COCOR_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_04487"
                     /product="16S rRNA (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="WP_014397292.1"
                     /sec_met_domain="TP_methylase (E-value: 3.5e-29, bitscore:
                     101.2, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGTLYLVATPIGNLGDVTARALETLRTVGFLACEDTRHSRILLD
                     HFGITGKDLVSLPAFAEGQRAGRILDRIEAGEACALITDAGSPGISDPGEKLVAEALER
                     GLKVEPVPGPTALVAALSASGLPTGRFHFLGFLPRKGPERRAMLDEVAPLSATCVLYES
                     PRRLAETLVDLQEAWGDRRACVARELTKLHEEFVRGPLSALVARYAGEETRGEVVVLVE
                     GRTGEQRWSEDEVRRALESGLARGEKLKPLSTELARRAGWPGQEVYRLGLGLKQR"
ORIGIN
        1 ggccccggcg tttccaccgg ggccctctca gagttgcggg ggcaggattt gaacctgcga
       61 ccttcgggtt atgagcccga cgagctacca ggctgctcca ccccgcgtca ccgtgacgcg
      121 gtactgcgat tctcgctttg aacacccggg gtcgaaactt tcatttcgac cccgggcttt
      181 tcaagttgcg ggggcaggat ttgaacctgc gaccttcggg ttatgagccc gacgagctac
      241 caggctgctc caccccgcgg cgagaacgag agggtaagta ccgaagcccc tcgctaccgt
      301 caacacctat ctcggcgccc gctcgcattg tctcgcgcga gcaccgagat ggcgtgacgc
      361 cactacttgc ccagcttgct gagcagatcc gcgaaggtgc cgaagccctt cttgccgccg
      421 cccaccggct gctgcgtctt ctgccacgcc tccacctcgg cgcgctcctc cgcgcggatg
      481 gccgcgggga tggacaggcg gatcttcccg gaggcgtcga tgtcgatgat cgccaccttc
      541 agctcctggc cgatggagaa gtgcttgcgc atgtccgtgc cgcgatccgt gcccgtctcg
      601 ctggcaggga tgagcccctt gccgcccggg aacgcgagga acacgccgta gggctccagc
      661 cggtccacct tgccgacgac gaccgcgccc accttgggac ggggcgccgc gggctccttg
      721 ggagccgacg gggcctgggc ctccttcgcg ggacgctcct cgggaggacg ctgggcctcc
      781 tcctcggaga tgcggcgcag gccgatgcgc ttgtcattgg ggtcgatctt ctcgacggag
      841 acccagatga cctcgccttc cttcaccgcg tcgcgcgggt gcgcgatgcg ccggtcgctc
      901 agcgcggaga tgtgcaccag gccgtccacg cccgggcgca gctccacgaa cgcgccgaag
      961 ggctggagcc ggacgacctt gccctgcatg cggtcgccct ccttgatctc ctccagcgcc
     1021 ttcttgaacg gatcctcctg acgcgaacgc agcgacaggg tgatgcgctc cttctgcttg
     1081 gacttgtccg gggagttggg ctggccctcc tccatgcgga ggatctccac ctccacctcg
     1141 tcgccctgct tcaccacgtc gctggggtga gcgacgcgcg tgtaggagag ctcggagacg
     1201 gggaccatgc cctccacgcc gcccaggtcc acgaacacgc cgaagtcgcg cacgccggag
     1261 accttgccct tgaccgtctt gcccacggcc aagttcttgc gcgtctccgt ggccagccgg
     1321 cgctgctcgt cctccagcag cgagcggcgc gacagcacca cgttgcggtc ccgcacttcc
     1381 gtcacgcgga actggagctt ctcgccgatg aactgatccg gcttctccac gaagcggatg
     1441 tccagctggc tgatggggca gaaggcgcgc gtctcaccga tggcgacttc cacgccaccc
     1501 ttgttcacgc tgaggaccag gccctccacc ggcatgccgg aggcgcgggc ctccgcgagc
     1561 atcgcgaagg acgcgttgcc cttggccagc gcgcggctga gctggatgcc ccgggcaccc
     1621 atctccacga cgtgcgcctc caggcggtca cccacgccga agcgcaggat gccctcgtcg
     1681 tccttgagct cgcggagctc gatcatcgcc tccgacttcg cggagccgtc cagcgacacg
     1741 aacgcggtgt ccgcgcccag ctggaagatg gtgccggcga ccttctcgcc aatgcgcacg
     1801 ccgcggcggc cgggagcgcc accgtccttg acctgcgcct cgaacatgtc cgcgaaggac
     1861 tcggtctccg ggacctcgtc gtacagcggg ctggacggcg cgggggccgg cgtcaccgga
     1921 cgcggggccg gagccggcgt cgaggccgcg gaggcctgcg cgtcggcgcc cgtctgctcc
     1981 gcggtcgcgg tcgcctcggc gggcttctca ccctccaggg cgcgcgtctc gatggagccc
     2041 gaggcccgct tcacgaccac catggggccg gacggacggc gctcgccgcc gcctcctcct
     2101 ccgctgccac cccggcgctc gccgccacgg ccaccgccgc gctcaccgcc accgcggggc
     2161 gcgtcgccct ggggacgggg ctgcgactgg gcgtcgcgag gaccgcgatc accgcggccc
     2221 ggcccgctct tctcatcgcg gccgccacgg ccaccgccgc gctcgttgcc ctggcccccc
     2281 gaagggatgc ccagcatcac gtcgccaaac gtggccttcg gcttcttggg accgaaaccg
     2341 ccaggaccgc ccgaatttcc gccgctcttc tcgtcgctca ctgccgagac cttccgttga
     2401 cgatttccga cccgggactt ccttgaagtc agggcctctt gaaaaaggcg gcggacttta
     2461 cacgcgcgcc atgcccggag gaagccgcat gcggccatcc ccttcacaat cggcctccta
     2521 tcccaacgaa aaggggcctg tcctgcattc cgtttgagcc cccagacacc gcctggaggg
     2581 cagccgtccc gccgggcgcc gcgccgcgtc taccggacga gcctcagctt ccggcccacc
     2641 ttgcggaaga cggcgcccgc ctccgggacc cccagcgcgg cggacaccgc gaagtagacc
     2701 aggccgaagg gcaccgccgt cgccagcagg cccagcaccg ggtgcagccg gggcggcacc
     2761 agcagggtcc cgccccactc cgcccccacc ccgggcatgg ggcccaggag gccggtgagc
     2821 ccctgtttga cggtcaacgc cacgagcccg cccaccaccg ccgcgacata aagccggggc
     2881 agcaggcccg aaggcgggcc cacgggcccg acgatggagc gcagcttgcg gcgcaggagc
     2941 gtggtctcca cccaggcgac gatgccgctg gacagggtga ggaacgccgc gcccagctcc
     3001 cggggcaggc ccagccgctc cggcagccac agcgccagga accaggcctt caccgacccc
     3061 agggacacac gcacgatggc gtagcgcagg ggcgtcttcg gatccttcag cgcgtagaag
     3121 gcggaggcgt agagccggcc cacggtggac gccaccaggc ccaccgccgc gcccatcagc
     3181 aggtaccaga gatagcgcga gtccgaggcg ccgaagcggc ccgtctgcaa gagcgcgccg
     3241 ctcaccaggt cccccaggaa gaagagcgcc acggcggagg gcaccaccca gaaggcgatg
     3301 cggcgcgagc ccgcgtcgat gcggctacgc agcttcgtat gcgcctgggc ctccccttcc
     3361 gccgtggcgc gcgccatctc cggcagctcc gcggcggaca ccgccatgcc gaagaggctc
     3421 accgggatga ggtagatggt ctgcgcgtag agcagcgacg acagcgcgcg gttggagatg
     3481 agcgacgcga aggcggtgtc cacccacgcg ctgaactgca ccacgccgcg ccccagcacc
     3541 accgggccaa agttcttcag cacctggcgc acggaggcgc tcgccagcga caccaccggg
     3601 cggaagtggc ccaacaggcg catcaccgtg ggcacctgca cggcgaactg gaggaagctg
     3661 cccagcacca cgccgtaggc cagccactcc gtcacggctt cttccgcggc gcgtcccccg
     3721 gccgtgccat gcaggctgcc caccaccagc agcgtggcga tgatgacgac gttccacacc
     3781 acgggcgcca ggtaggacag caggaagcgc cggtggctgt tgaggatgcc caggcaccac
     3841 gcgctcagca ccaggaagcc cgtgcccggg aagaggatgc gcaccagccg cacggccagg
     3901 tcgcgctcgc cgccctcgaa gcccggcgcg atgaggtcca cgaacagcgg cgtggccagc
     3961 atgcccagcg ccaccatcac ggcggtggcc atggccagga gaccgaacac cgcgcccgcg
     4021 acccggtccg cctcgtccgc gtccttcttg cccagcagct gggcgtagac ggggatgaag
     4081 gagcccgaca gcacgccttc accaaagagg ttctggagga agttggggat gcgcagcgcg
     4141 gccttgaaga cggcggcggc ctccgcgttg cccaggtagt gcgcgaagac ccgctcgcgc
     4201 accagcccca tcaggcgcga tgccaggatg ccaatgccca ccagcatcgc gccccggcct
     4261 cccgcgctgc gttcagggct ggacggaaga ggggcggccg gagagccggc ggaagggggc
     4321 gaggcgggtg cgggggcggt cacgaagggg cggactctac gtccggcgtt cttcggcatg
     4381 cagcaggaaa cccttcgacc gctgtttcac ttgacggtca ccccacgggt tgcgagggtc
     4441 cgcccccaat ggccggaaag tccgacaccg agcggtccga cgtcgcgcgc atccgcgccg
     4501 tcctggcgcg cgaactcgag accatcaacg agtacgaggc gttcgccgag gactcctcga
     4561 atccggaagt gaaggccttc ttcctccacc tggcggcgga ggagaaggag cacgtgtccg
     4621 aggcgaccca catgctccgc atgctcgaca agggtcagga cgcgcacttc gccaagccct
     4681 tcgtccccgg ccacttccag gcagccgtgg ggagtgtccc ctcggagccc gccctgcccg
     4741 ccgccgaacc cgtgcacgcg gcgccacccg ccccgcccgc ggtgggccgc ctggcgaacg
     4801 agcccctgac gtccctgccg ccccagcgcc tcatctatgg cgtccccgcg ccgccgcctt
     4861 cggccaacgg ccatccgctc accatcggca gcctgcgccg cggcggtgga agcggcggct
     4921 ccggtggcgg tcgttagaac cctttcgttt cctgacttcg cttctcccct cctctgccgc
     4981 cgctcgtgac ggagacaccg atgcctgact tccttggaca tgccgagaac ccgctgcgcg
     5041 aagaggagtg ggcgcgcctc aacgagacgg tgatccaggt ggctcgccgt tcgctggtgg
     5101 gccgccgcat cctggacatc tacggtccgc tgggcgcggg cgtgcagacg gtggcctacg
     5161 acgagttcca gggcgtgtcc ccgggcgcgg tggacatcgt cggcgagcag gagaccgcga
     5221 tggtcttcac cgacgtccgc aagttcaaga ccatccccat catctacaag gacttcctgc
     5281 tgcactggcg ggacatcgag gcggcgcgca cgcacaacat gccgctggac gtgtccgccg
     5341 ccgccggtgc cgccgcgctg tgcgcgcagc aggaggacga gctcatcttc tacggcgacc
     5401 agcgcctggg ctacgagggc ctgatgacgg ccaacggccg cctcaccgcg acgctggggg
     5461 attggacggc gccgggcggc ggcttccaga ccatcgtgga ggccacgcgc aagctcaacg
     5521 aggccggcca cttcggcccc tacgccgtgg tgctgtcgcc gcgcctgtac tcgcagctgc
     5581 accgcatcta cgagaagacg ggcgtgctgg agatccagac catcagccag ctcgcggccg
     5641 acggcgtcta ccagtccaac cgcctgcgcg gtgagtccgg cgtggtggtg tccacgggcc
     5701 gggagaacat ggacctggcg gtggccatgg acatggtcgc ggcctacctg ggcgccagca
     5761 agatgaacca cccgttccgc gtgctggagt cgctgctcct gcgcatcaag cacccggacg
     5821 ccatctgcac gctggaaggc gccgtccccg ccgctccccc ggcgcgccgc tagtcctctt
     5881 cctttcgcgc ggaggcttat ggccaaggtc ctggtcatcg acgacgagac gaacctgcgc
     5941 aaggtgctgg ccgccctgct gcgccgcgac gggttcgacg tcaccgtggc ggagaacggc
     6001 gagcagggcc tggccgagtt ccacaagaac ggcgcggaca tcgtcgtcac cgacctggtg
     6061 atgcccaagc tgggcggcat ggaagtgctc gccgccgtgc gcgccgccaa cccggacgtg
     6121 ccggtgatca tcatcaccgc gcacggcacc gtggactccg cggtggaggc catcaaggcg
     6181 ggcgcgttcg actacatcac caagcccttt gatcaggcgg agctgtcctc cgtcgtggcc
     6241 aaggccgcca agacgaacga gagcgccaag cgctccgtgc gcgcggacca caaggcccgg
     6301 tccgccatca tcggcgagtc gccgcagatc caagacgtct acaagatcat cgacaaggtc
     6361 gcggacacgc cctccacggt gctgatcacc ggcgagagcg gcacgggcaa ggagctcatc
     6421 gccaccgcgc tgcacggcgc gtccagccgc cgcgacaagc cgttcatcaa gatcaactgc
     6481 gccgccattc ccgccacgct gttggagagc gagctgttcg gctacgagaa gggcgccttc
     6541 accggcgccg tcacgtccaa gcccggccgc ttcgagctgg ccgacgaggg caccctcttc
     6601 ctggacgaga ttggtgaaat ccccgtcgag atgcaggtga agctcctgcg cgcgctccag
     6661 gagggcgagt tcgagcgcgt gggcggcatc aagacgacgc gcgtgaacgt gcgcctggtg
     6721 gccgccacca accgcgatct ccaggcggag atcgaagcgg gccgcttccg caaggacctg
     6781 tactaccggc tggccgtggt gcccatcgtg ctgcccgcgc tgcgcgagcg ccggggcgac
     6841 atcccgatgc tcgccgcgca cttcgtggac aagtacaacc ggcggctcca caagaagatc
     6901 gaaggcatcg ccgatgacgc gctcgcgctg ctccaggcgt atgcgtggcc gggcaacatc
     6961 cgcgagctgg agaacctcat cgagcgcgtg ctgctcttcg ccgatggccc cctcatcacc
     7021 gcgaaggacc tgccggagcc ggtgcgcggg ggagcgggcg tgcaggcagg ggcacaggtc
     7081 gccgcctcgc tgggcacgct ggacgtccct gtgggcgaag tgggcctcaa ggacatcgtg
     7141 cgcatgaagg ccgcggagct ggagcgggac ctcatcgtca agaagctcga ggagacgggc
     7201 ggcaacgtca cgcgcgccgc gcgcctcctg cagatcagcc gcaagtcgct ccagacgaag
     7261 atgaaggagt tcggcctgcg cgacaccacc ccggacggtc aggaagacgg cccggacgag
     7321 tagcctgggg gcgccgaaat atcgcctttt cgtcggcggt ttcggccccc gcgtaccttc
     7381 ttaccctcag ggagcctgaa tgcggccgaa tcttcccacc ctcggtggac caccgaagcg
     7441 caatcccttc ggaccggtgg ttgccgtctc cgtcatcctc ggcgcggccg cgggtggcgt
     7501 gtggtggtgg aaacagcgca tggcggatgt ccccatggac gtcgcctcgc agaccgcgtc
     7561 cgcgctggac gccggcaccg tggcccaggc ccccgtggcc ccgcccgcgc ccaccgaccc
     7621 cgtgaaggcc gcgggcctgg agcgcgtgtc catccgcatc gagggcccgc tggagacggc
     7681 gctcgtccag gcctccgacg ccaccgtggg ccccgccctg gcgcaggtgg tgacgcgcac
     7741 actggtgtgg tgggtgcgcg tacccggcga aatcctacgg ggtgacaccc tggacgtgct
     7801 cttccagcgc cgccccaacg aggagccgct ggtgtacgcg gtgcgcttcg tgagcggcaa
     7861 gacgggccag acgcaccgcg cctaccgctt cacgcccgcg ggtgaggcga acgcccgcta
     7921 ctacctgccc ggcggcgacg agctggagct gcggatggag aagtccccca tcgacagcta
     7981 cgagcagatc acctcgctgt tgcgcgacgg ccgcggccac aagggcgtgg acttccgcgc
     8041 gccggtgggc acgacggtcc gggcgccctt cgcgggcgtc atcaagcgca agaactggaa
     8101 ttttggcagc aacggcaact gcatcgagct ggtggaaacc gggggcaagg gccgccgcgc
     8161 cctcttcctg cacctggcgg agctgcccaa gaacatccag gccgggatgc gcgtgaacgc
     8221 gggccaggtg ctggcccaga gcggcaacac gggccactcc ttcgcccccc acctgcacta
     8281 ccagctcatg ctgggcgaaa accgggtcct ggaccccttc gaccagcaca agaccttccg
     8341 cgcgtccctg gcggccgccc acaagggcgc cttcgacacc gaggtccagc ggctggatgg
     8401 attgctggga acctccgtcg cggggaagta aagccccacc catttcttga cactcctccg
     8461 acggcacggc tagctggcag ccctgggccg tggtcgtcgg aggtagtgga tgcacaggtt
     8521 tcgcgccgtc atcgccgcgc tgacgctggg cgtgcctttc gccgccagcg cggcggagat
     8581 cacccggatt gcttcctcgt tcgaggatga tgatccgttc gacctcttcc tcgacgtggg
     8641 cttcgagcgc acgcagacgc gcgcgaagat cgtccgcgag cagcttcgcg gcggtgacgc
     8701 caccgacgtc tcggaggtca acgagctctg gtacaagggc acggacgcgc ggctgaatct
     8761 ggccgtggcc ttcggcctgt ggaaggacct ggagttcagc ttcaagctgc ccatcgtctt
     8821 ccagcagaac gagacctgga acttcgtgtc cggcacgaac cagggcaact ccaccatcac
     8881 caacagctgc tacaacgcgg acggctcgcc ctactccgcc gagggctgcg tgggccggct
     8941 gttccaggtg ccacaggaga gctaccgcgg cggcctgggc aacgtgcact tcggcctggc
     9001 gtacgccttc ttcaaccagg agaaggacga caccaagccc acgtggatcg tcggcatcga
     9061 ctacgaggcg cccaccgcca agcagcgcga cccgagcctg aacaacaccg acccggacgg
     9121 cgatcgcggc aacgtgggcg accgcgtcca caagtaccag ctctacacca ccttctcgcg
     9181 gaagatgggc gtggcggagc cgtacttcaa ggcgtcccac accatcccgg tgcgcggccc
     9241 cggcgcctac tccaactgcg atcagtccag cctcccctac ccggggaacc tgggcgcgcc
     9301 gtacaactgc tacaaggagc cgtggacccg ccacgagacg ggcatcaagg ccccctcgca
     9361 gacggcgctc accttcggca tggagctggt gcccttcgag aacgcggcca ggtcccagaa
     9421 gttcgccctg gacgtgcggc tcctgggcaa ctacgtgggc cgcggccggt actacaacga
     9481 gctgacctcc gcgctgcgca agctgctcac ctccgacgac tacttccagg tgggtggcca
     9541 ggtgggcgtc accgcccgcg ccgcccaggc cttcaccatc cgcgcctccg gcaacttcct
     9601 ctacaacacg gaccacctgc tcacgtccga ggccattggc caggacctga acggcgacgg
     9661 ccaggtggac acggcggtgg gctcgccgga gctgaacccc acgttcgact ggcgctacga
     9721 cctggtatcc cgccgcttcc gggccatcca gagcaccacg ttccgcttcg acctgggcgc
     9781 gaccttcagc ttctgaagtc ccgcctgaag cagcggcggg ccttccctac cgctgcttca
     9841 gccccaggcc cagccggtac acctcctggc cgggccaccc cgcgcggcgg gccagctccg
     9901 tgctcagcgg cttgagcttc tcgccgcgag ccaggcccga ctccagcgcc cggcgcacct
     9961 cgtcctcgct ccagcgctgc tcgccggtgc ggccctccac cagcaccacc acctcgcccc
    10021 gggtctcctc gcccgcgtag cgcgccacga gcgcggacag cggcccccgg acgaactcct
    10081 cgtgcagctt ggtcagctcg cgcgccacgc acgcgcggcg gtcgccccag gcctcctgga
    10141 ggtccaccag cgtctccgcc aggcggcgcg gggactcgta gaggacgcag gtggcggaca
    10201 ggggcgccac ctcgtccagc atggcccggc gctccggtcc tttccgaggc aggaagccca
    10261 ggaagtggaa gcgcccggtg ggcaggccgg acgcgctcag ggcggccacc agcgccgtgg
    10321 ggccgggcac cggctccacc ttcaggccgc gctccagcgc ctccgccacc agcttctctc
    10381 ccgggtcgct gatgccgggg ctgcccgcgt cggtgatgag cgcgcaggcc tcccctgcct
    10441 cgatgcggtc caggatgcgc ccggcgcgct gcccttccgc gaaggcgggc aggctcacca
    10501 ggtccttccc ggtgatgccg aagtggtcca acaggatgcg cgagtgccgg gtgtcctcgc
    10561 acgcgaggaa gcccacggtg cgcagcgtct ccagggcccg ggcggtgaca tcccccaggt
    10621 tcccgatggg cgtggccacg aggtagagcg ttccagccaa gggacggatt cctttacatg
    10681 ccagcgtcga aggcggcggg caggtgctcc acccgggcgt gctcgccctg gcccacgacg
    10741 gagatgacgt cgaagcgcac catgcgcccg tcgatgccat tctgaaagag atagtgcagc
    10801 gcggccttca ccacccggcg ctgcttggcg aaggacacgg tgtgcgacgg gtctccccac
    10861 gccgccgtgg agc
//
