LOCUS       NC_017030              10849 bp    DNA     circular CON 20-MAR-2024
DEFINITION  Corallococcus coralloides DSM 2259, complete sequence.
ACCESSION   NC_017030
VERSION     NC_017030.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus coralloides DSM 2259
  ORGANISM  Corallococcus coralloides DSM 2259
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Kneip,S., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Complete genome sequence of the fruiting myxobacterium Corallococcus
            coralloides DSM 2259
  JOURNAL   J Bacteriol 194 (11), 3012-3013 (2012)
   PUBMED   22582372
REFERENCE   2  (bases 1 to 10080619)
  AUTHORS   Huntley,S., Zhang,Y., Treuner-Lange,A., Sensen,C.W. and
            Sogaard-Andersen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-MAR-2012) Ecophysiology, Max Planck Institute for
            Terrestrial Microbiology, Karl-von-Frisch Strasse 10, Marburg, Hesse
            35043, Germany
COMMENT     ##Assembly-Data-START##
            Assembly Method :: Newbler v. 8/10/2010; Celera v. 8/10/2010
            Coverage                          :: 42-fold
            Sequencing Technology             :: Sanger dideoxy sequencing; 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000255295.1-RS_2024_03_20
            Annotation Date                   :: 03/20/2024 02:27:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,155
            CDSs (total)                      :: 8,082
            Genes (coding)                    :: 8,042
            CDSs (with protein)               :: 8,042
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 11 of 40
            Pseudo Genes (incomplete)         :: 26 of 40
            Pseudo Genes (internal stop)      :: 6 of 40
            Pseudo Genes (multiple problems)  :: 3 of 40
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:31:27
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3012801
            Orig. end                         :: 3023650
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003389.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="9"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10849
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5849](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            1075..1599
                     /locus_tag="COCOR_RS12445"
                     /old_locus_tag="COCOR_02497"
     CDS             1075..1599
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637552.1"
                     /locus_tag="COCOR_RS12445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02497"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_014395325.1"
                     /transl_table=11
                     /translation="MSEQAANPRTRTVTWRDPQEGASAAKKLSGLEYLRAIQRGELPAP
                     PIAELMGFAPVEVEEGRVVFAVKPGEHHYNPIGMVHGGLAATLMDSAMGCAIHTMLPVG
                     AGYTTLELHVNYVKGIAHDTGPLLCRGEVIHLGGRVATAQGRLVDEKGTLYAHGTTTCM
                     VFRPPGAGGKE"
     gene            1605..2306
                     /locus_tag="COCOR_RS12450"
                     /old_locus_tag="COCOR_02498"
     CDS             1605..2306
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637553.1"
                     /locus_tag="COCOR_RS12450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02498"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_014395326.1"
                     /transl_table=11
                     /translation="MRYTAEHKQATHARILAAAEMLFRAEGFSGASVERVMRAAGLTVG
                     GFYAHFTSKESLLAESLRAFMTARRTPWLAGLEGMRGPAFLDRFARRYLDQYNRDTGDT
                     TCMMPSLLSDLTRAAPEVQAAFAQGLEDLVGQAQTHLPAREGATPRQQMLATVTLCFGA
                     MTLARATASQPLAAEILDAARALLVAGAPVEGSARNDAPRAHAAPRRVPASRKKAPSRK
                     RQVGSARKKPL"
     gene            2422..3849
                     /locus_tag="COCOR_RS12455"
                     /old_locus_tag="COCOR_02499"
     CDS             2422..3849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002637554.1"
                     /locus_tag="COCOR_RS12455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02499"
                     /product="hypothetical protein"
                     /protein_id="WP_014395327.1"
                     /transl_table=11
                     /translation="MTTVARAWRVALALTLGACASVPLAPPWEDVPLRYDITYTHDPSP
                     RLKVEVTLPPSPPGVFPGSFLFRQPGRESSVIATFGNGSRAEIFPRDGVVRVPEGARSL
                     RYHYPLASSSRGGGRHLFGGMGEGDTWHVGGKAYLLTPSRVTPDLRVDLTVSGADALLP
                     WTPDDRGVYHLRGEDLIDAGFHSFGGRRCQVHVGASVLEVALLGHFTHLTDADICAWLE
                     QAGREVVTVRRAFPYPHVTVRVVPVPGDDTPGVFGMTLWSSPPSISILVGQDATAVSFA
                     KDWVAVHEMLHLTHPALVPRVAWLTEGLTTYYTELARARSGRQPAQQAWQELVNGFARG
                     HAASRSRPMKEVVAEERNFMGIYWTGALFALHLDVELRRVTNGRARLEDVLELLATRGP
                     TATLESFGDAVDTVAGQPLFDALLARHLSGPAFAALDPLLEDLGVRIDPGGVKLHAAPG
                     SGVREALDGERTPDDAG"
     gene            3943..4566
                     /locus_tag="COCOR_RS12460"
                     /old_locus_tag="COCOR_02500"
     CDS             3943..4566
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611302.1"
                     /locus_tag="COCOR_RS12460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02500"
                     /product="YceI family protein"
                     /protein_id="WP_014395328.1"
                     /transl_table=11
                     /translation="MFRSVLMLAATLSLSASAAEPAASDKHFVFHDPNSRDTVMFVLDA
                     PLEVINGLSNQVTGRVDVKGQKASGRFQVPVKSIKTGNETRDGHLQNDRWLDAAKHPDI
                     IFEFKDVALPAPLANAKPVVLKTKGTFTIHGVTREEPVEVTATYLQETAETKNRAAGEL
                     LRVRAKFQIPLEAYGIQRTEALVLKVGERAEVTVDAWGSTQFKP"
     gene            4625..4876
                     /locus_tag="COCOR_RS12465"
                     /old_locus_tag="COCOR_02501"
     CDS             4625..4876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013376936.1"
                     /locus_tag="COCOR_RS12465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02501"
                     /product="hypothetical protein"
                     /protein_id="WP_014395329.1"
                     /transl_table=11
                     /translation="MNVKALAAVVGTLSLGALATGCASNKAAEGSKVHAASPGAPEASE
                     SSAAPAAEGAAPAAAPEKGAEGSCGAGSCGAGSCSGKK"
     misc_feature    4931..4945
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            5001..5849
                     /locus_tag="COCOR_RS12470"
                     /old_locus_tag="COCOR_02502"
     CDS             5001..5849
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002614260.1"
                     /locus_tag="COCOR_RS12470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02502"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_014395330.1"
                     /sec_met_domain="DUF692 (E-value: 2.4e-96, bitscore: 320.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPRYADRHGLKPLGAGIGLRRDFYEALPRTPRALDWVEIIPEN
                     FLTLGGRSQRALDACRERWTLLPHGVGLNIGGPDALDDDYVTRLAALVKRLDAPFFSDH
                     LCYSRLGGVHLHDLLPLPFTEAAVEHVVPRVREVMARVERPFLLENPSYYAAMPGGTLR
                     EADFLRQVVEAADCGLLLDVNNVWVNARNHGYDPRAFVDALPLERVVQVHLAGHDVRET
                     VLIDTHGDRVCDDVWSLYRYTLERTGPVSTLIEWDQAIPSLDAVLDEADQARAVLAEGA
                     R"
     gene            5846..6583
                     /locus_tag="COCOR_RS12475"
                     /old_locus_tag="COCOR_02503"
     CDS             5846..6583
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015350978.1"
                     /locus_tag="COCOR_RS12475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02503"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_014395331.1"
                     /transl_table=11
                     /translation="MKSSLKHFFDSMDAYLAGPPGAEGLLKLSASHPGWDVDPERMALY
                     GQFVRGHVRSTLEKLFPLTRKAVTPETWDALVDGYTRTRPARHYELNRLGEGFAPFVSD
                     AAAAKGLPPFLPALARFEWTDFAVFASEEDIPDAVERLTPNPTLTVLENPYRLCAFVRA
                     RGAESVPAEGEELALLWRHPERLVTFFMAATPPALLVLKMAVEGLSEEAVVQATGMSAA
                     DLHAEVVRFAKDGLVLAPASRIH"
     gene            6717..7280
                     /locus_tag="COCOR_RS12480"
                     /old_locus_tag="COCOR_02504"
     CDS             6717..7280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013376934.1"
                     /locus_tag="COCOR_RS12480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02504"
                     /product="chalcone isomerase family protein"
                     /protein_id="WP_014395332.1"
                     /transl_table=11
                     /translation="MKKTLTAVLLSLTLAAPVMAKDIAGVKYPDTATVAGKELKLNGVG
                     LRKKAIFKVYTLGLYVENPTQDATALLNADEVKRVRMFMKRDLKKDQITEAIENGFKKS
                     AGANMPKLQARLDAFKAAIPAEVKEGQELNLTYVPGKGTTVQVTGGQSIDVEGKDFADA
                     LFSVWLGKDPVDGGLKDGILGKED"
     misc_feature    7411..7423
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 21.19"
                     /tool="antismash"
     gene            7512..9647
                     /locus_tag="COCOR_RS12485"
                     /old_locus_tag="COCOR_02505"
     CDS             7512..9647
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012632590.1"
                     /locus_tag="COCOR_RS12485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02505"
                     /product="M13 family metallopeptidase"
                     /protein_id="WP_043322955.1"
                     /transl_table=11
                     /translation="MKRLALFAASCVLGAACKTAEPTPEPPQATTPAPVAAAAPATPAP
                     EAPAVPMSERPMPPGLDAAVMDPSVNPCDDFYQYACGGWLQATEIPAERARWSRGFETV
                     AERNQTVLRDILTKAAEGQGEGTPEDKKLGDFYGSCMDEAKLEQSLPTLRTYLAKLNGL
                     KSQQAVASAVAWLHARDVNALFRVGSDQDQKDATQVIAIVDAGGLGLPDRDYYLKPDVK
                     MREARNAYQAHVQKVFELLGDAPFVASRKAIGILAIETRLANARLPKEERREPEKVYHR
                     LERQGLKKLAPAFQWDTYFAEVGLPAGEALNVTEPKFFSEVSALVRQQRPTDMGPYLSY
                     HLVKDVQTALPKALRDEFFRFESSVLTGAKADLARWKKCVDATDDALPHALAKPFIART
                     FGADGKATTLDMVQQIEQSFERNLDTLSWMDAETKAQALVKVKKITNKIGYPDQWRSYD
                     GLTVTRDSYLDNLLAADAFEQARQLRKVGQPVDRQEWFMSPPTVNAYYNAATNEIVFPA
                     GILQPPFFGRDASAAVNFGAMGMVVGHEITHGFDDEGRQFDADGNLRTWWTPASDKAFR
                     ERVSCVKNQYDQYTAVDDVKVNGKLTLGENVADLGGLKLAYAAMEAYLAKHPDQAAKAN
                     SYRFTPGQQFFLAHAQSWCSKIRNEAARQRALTDSHSPAFLRVKGPDVNLPQFQQAFSC
                     PAGSPMVAPAANRCEVW"
     gene            9674..9922
                     /locus_tag="COCOR_RS12490"
                     /old_locus_tag="COCOR_02506"
     CDS             9674..9922
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013941499.1"
                     /locus_tag="COCOR_RS12490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="COCOR_02506"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_014395334.1"
                     /transl_table=11
                     /translation="MSICSWLVLGGIAGWLASIIKGTNARMGMFANIFAGIVGSMLGGW
                     VFSFFGGRGVTGFNLYSLLVATVGAVILLSILQAIRK"
     misc_feature    10430..10446
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.64"
                     /tool="antismash"
ORIGIN
        1 ggcgagcgtc ttcgccgcgt cgccgaacac cttcgcgatg ccctccatct ccagcaggtc
       61 gccaatgtcc gtcgaggtgc cgtgggcgtt gaggtagccg atgtccgcgg ggttgaggcg
      121 cgcgttcttc agggaggcct tcatcgcgcg ctgggcgccc tcgtggccgg gggcgggcga
      181 ggtgacgtgg taggcgtcgg agctggcgcc atagcccgtg agctccgcga ggatgcgggc
      241 gccccgggcg cgggcgtgct cgtactcctc caggacgagg atggccgcgc cttccgcgag
      301 cacgaagccg tcgcggtcct tgtcgaacgg gcggctcgcc gcctggggcg cgtcgttgcg
      361 gttggacagg gccttcatcg cggcgaagcc gcccacgccc agcatggaga tgggggcctc
      421 cgcgccgccg gccagcgcca cgtcgaactc gccgcgctgg atgccgcgca gcgcctcacc
      481 gatggcgtgc gcgctggtgg agcaggcgga gttggtggac caggacgggc ccttgatgcc
      541 gtggcgcatg gagatgtagc cgggcgccat gttgatgatc atctggagga tgaagaagga
      601 gctgatgcgg tccggcccct tctccagcgc cttgcggtgg gtctcctcca ggctgctgag
      661 tcccccgatg ccggagccga tgacggccgc cacgcgctcc gcgttctcct cggtgatgac
      721 cagcccggag tcctcgaggg ccatgtccga cgcggccacc gcgaactgcg cgaagcggtc
      781 catgcggcgc acctcgcgcc gttcgatgta gtcctccgga ttgaagccct tcacctcacc
      841 ggcgaagcgg cagtccagcg cgctcgcgtc gaacagggtg atgggcccca cgccactctt
      901 gccgttcacc agcgcgtccc agctcttctc cacgccgatg ccacaagggc tgatgagccc
      961 cattcccgtc accacgacgc gccgctgttc catcgcgcac tccttgaccc tgttcgttga
     1021 accgggatgg tattatgacc atccttccat gagttcaagc ccaagggagc cccgatgagc
     1081 gagcaggcag cgaatccgcg cacgcggacg gtgacatgga gggacccgca agagggcgct
     1141 tccgcggcga agaagctgtc ggggctggag tacctgcgcg ccatccagcg cggggagttg
     1201 ccggcgccgc ccatcgcgga gctgatgggc ttcgcgccgg tggaggtgga ggagggccgg
     1261 gtggtgttcg cggtgaagcc gggcgagcac cactacaacc ccattggcat ggtgcacggc
     1321 ggactggccg cgacgctgat ggactccgcc atggggtgcg ccatccacac gatgctgccg
     1381 gtgggcgcgg gctacacgac gctggagctt cacgtgaact acgtgaaggg cattgcccat
     1441 gacacgggac cgctgttgtg caggggcgag gtcatccacc tgggcggccg cgtggcgacg
     1501 gcgcaggggc ggctggtgga tgagaagggc acgctctacg cgcacggcac cacgacgtgc
     1561 atggtgttcc ggccgccggg cgcgggcggc aaggagtagg ggcgatgcgc tacaccgctg
     1621 aacacaagca ggccacgcac gcgcgcatcc tcgcggcggc ggagatgctg ttccgcgcgg
     1681 agggcttcag cggtgcgagc gtggagcggg tgatgcgggc cgcgggcctg acggtgggcg
     1741 gcttctatgc ccacttcacc tccaaggagt cgctgctcgc ggagtcgctg cgcgccttca
     1801 tgacggcgcg caggacgccc tggctcgcgg ggctggaggg gatgcggggc ccggcgttcc
     1861 tggatcgctt cgcgcggcgc tacctggacc agtacaaccg ggacacgggc gacacgacct
     1921 gcatgatgcc gtcgctcctg tcggacctga cgcgcgcggc gccggaggtg caggccgcgt
     1981 tcgcccaggg gctggaggac ctggtcggcc aggcccagac gcacctgccc gcgcgcgagg
     2041 gcgccacgcc ccggcagcag atgctggcga cggtgacgct gtgcttcggc gcgatgacgc
     2101 tcgcgcgggc caccgcgtcc cagccgctgg cggcggagat actggacgcg gcgcgtgcgc
     2161 tgctcgtcgc gggggctccc gtggagggga gcgccaggaa tgacgcgcct cgcgcgcacg
     2221 cggcgccgcg cagggttccc gcctcgcgca agaaggcgcc ctcccggaag cgccaggtgg
     2281 gctccgcgcg caagaagccc ctctgagcgg acgtccatgg gcgcgtcctc gtgcgtcgac
     2341 attccgggct ggacggcatg ggggccgccg tggagtcctt ccgcgcggac cgcggaccgt
     2401 gggggcaggg tgcacgcaag gatgacgacg gtggcccgcg cgtggcgggt ggcgctcgct
     2461 ctcacgctgg gggcgtgcgc ctccgtgccg ctcgcgcctc cctgggagga cgtgcccctc
     2521 cgctacgaca tcacgtacac gcacgacccc tcgccgcgcc tgaaggtgga ggtcaccctg
     2581 cctccgtcgc ctcctggtgt cttccctggc tcgttcctct tccggcagcc ggggcgcgag
     2641 agctccgtca tcgcgacgtt cgggaacggg agcagggccg agatcttccc ccgggacggc
     2701 gtggtgcggg tgcccgaagg agcgcgaagc cttcgctacc actacccgct ggcctcctct
     2761 tcccgagggg gcggcaggca cctgttcggg ggcatggggg agggcgacac gtggcacgtg
     2821 ggcggcaagg cctacctgct gacgcccagc cgcgtgacgc ccgacctgcg cgtggacctc
     2881 accgtgtccg gcgcggacgc gctcctgcca tggactcctg atgaccgggg cgtctaccac
     2941 ctgcgcggcg aggacctcat cgacgcgggc ttccattcgt ttggcggcag gcggtgccag
     3001 gtgcacgtcg gcgcctccgt gttggaggtc gcgctcctgg gccacttcac gcacctgacg
     3061 gacgcggaca tctgcgcgtg gctggagcag gccgggcgtg aggtcgtcac cgtgcgcagg
     3121 gcgttcccgt atccgcacgt caccgtgcgc gtcgtgcccg tgcccggcga cgacacgccc
     3181 ggagtcttcg gcatgacgct atggagctcg ccgcccagca tctccatcct cgtggggcag
     3241 gacgccaccg ctgtgtcctt cgcgaaggac tgggtcgcgg tccacgagat gctgcacctg
     3301 acgcacccgg cgttggtgcc ccgggtggcc tggctcaccg aggggctgac cacctactac
     3361 acggagctcg cccgcgcgcg ctccggacgc cagccggccc agcaggcctg gcaggagctg
     3421 gtgaacggct tcgctcgcgg tcatgccgcc tcgcgctcac gccccatgaa ggaggtcgtc
     3481 gccgaggagc ggaacttcat gggcatctac tggaccggcg cgctcttcgc gctccacctg
     3541 gacgtggagc tgcgccgcgt gacgaacggc cgcgcacggc tggaggacgt gctggagctg
     3601 ctcgccacgc gcggccccac cgcgacgctc gaaagtttcg gtgacgccgt ggacacggtc
     3661 gcgggccagc cgctgttcga cgcgctgctt gcccgtcacc tttcagggcc tgccttcgct
     3721 gcattggacc cgttgctcga agacctgggc gtccgaattg acccaggcgg cgtcaagctc
     3781 catgctgcgc cgggcagtgg ggtgcgtgag gcactggacg gcgagcggac cccggacgac
     3841 gcggggtgaa cacctggaaa gagaaagggc cgtaacccat tcccggctgt cgcgtatcgc
     3901 atgcatccgc gaggttcgcg gcatccgtag atgaggtccg ccatgttccg cagcgtcctg
     3961 atgctcgccg ccaccctgtc gctgtccgcg tccgccgcgg agcccgcggc ttccgacaag
     4021 cacttcgtct tccatgatcc gaacagccgc gacacggtga tgttcgtgct ggacgcgccg
     4081 ctggaggtca tcaacggcct gtccaaccag gtgacgggcc gcgtggacgt gaaggggcag
     4141 aaggccagcg gccgcttcca ggtgccggtg aagtccatca agacgggcaa cgagacgcgc
     4201 gacggccacc tgcagaatga ccgctggctg gacgcggcga agcacccgga catcattttc
     4261 gagttcaagg acgtggccct gcccgcgccg ctcgccaacg cgaagccggt ggtgctgaag
     4321 acgaagggca ccttcaccat ccacggcgtc acgcgcgagg agcccgtgga ggtgacggcc
     4381 acgtacctcc aggagacggc cgagacgaag aaccgcgccg cgggcgagct cctgcgcgtg
     4441 cgcgcgaagt tccagattcc cctggaggcc tacggcatcc agcgcaccga agcgctggtg
     4501 ctgaaggtgg gcgagcgggc cgaggtcacg gtcgacgcct ggggctccac gcagttcaag
     4561 ccgtagcgat gtgtcgtcag ttcccccgta gtcacacccc acgcggtacg aaaggaagca
     4621 acacatgaac gtcaaggctc ttgcggcggt tgtcggcacc ctgtccctcg gcgcgctggc
     4681 caccggctgt gcgtccaaca aggcggcgga gggcagcaag gtgcacgccg cttccccggg
     4741 cgcccccgag gcctccgagt ccagcgcggc ccctgccgcc gagggtgctg ctcccgccgc
     4801 ggcccctgag aagggtgccg agggctcctg tggcgccggc tcctgcggcg ctggctcctg
     4861 cagcggcaag aagtagtcac tccccgggag ggcctgcgtg acaggtctcc tcccaggctc
     4921 gcgggcggcg ggaagagtcc ttcctgccgc ccgtgttgtt tccaccctgc aagctcccaa
     4981 gctccaagga gaagcgccgc atgccgtccc cccgctacgc agaccgccat ggattgaaac
     5041 cgctgggggc gggcatcggg ttgcgccgcg acttctacga agcgctgccg cgcacgccgc
     5101 gcgcgctgga ctgggtggag atcatcccgg agaacttcct cacgctgggc ggccgctccc
     5161 agcgcgccct ggacgcgtgc cgcgagcgct ggacgctgct gccgcacggc gtgggcctca
     5221 acatcggcgg gccggacgcg ctggatgacg actacgtcac ccgcctggcc gcgctggtga
     5281 agcggctgga cgcgccgttc ttctcggacc acctgtgcta ctcgcggctg ggtggcgtgc
     5341 acctgcatga cctgctgccg ctgcccttca cggaggccgc ggtggagcac gtggtgccgc
     5401 gcgtgcgcga ggtcatggcg cgcgtggagc gccccttcct gctggagaac cccagctact
     5461 acgcggccat gccgggaggc acgctgaggg aggcggactt cctgcgccag gtggtggagg
     5521 ccgcggactg cgggctgctg ctggacgtga acaacgtctg ggtcaacgcg aggaaccacg
     5581 gctacgaccc gcgcgccttc gtggacgcgc tgcccctgga gcgcgtggtg caggtgcacc
     5641 tggccggcca cgacgtgcgc gagacggtcc tcatcgacac gcacggcgac cgcgtctgcg
     5701 atgacgtgtg gtcgctgtac cgctacacgc tggagcgcac cggaccggtg tccacgttga
     5761 ttgagtggga ccaggccatc ccgtccctgg acgccgtgct ggatgaggcg gatcaggcgc
     5821 gcgccgtgct cgcggagggt gcgcgatgaa gtcgtcgctg aagcacttct tcgacagcat
     5881 ggatgcgtac ctcgccgggc cgcccggcgc ggaggggctg ttgaagctgt ccgcgtcgca
     5941 cccgggctgg gatgtggatc cggagcgcat ggcgctctac ggccagttcg tgcgcggcca
     6001 cgtgcgctcc acgctggaga agctcttccc gctgacgcgc aaggcggtga cgcccgaaac
     6061 gtgggacgcg ctggtggacg gctacacccg cacgcggccc gcgcggcact acgagctcaa
     6121 ccgcctgggc gagggcttcg cccccttcgt ctcggatgcc gccgccgcga agggactgcc
     6181 gccattcctg cccgcgctcg cgcgcttcga gtggacggac ttcgcggtgt tcgcctccga
     6241 ggaggacatc ccggacgccg tggagcggct gacgcccaac cccacgctca cggtgctgga
     6301 gaatccctac cggctctgcg cgttcgtgcg ggcccggggc gcggaaagcg tgccggcgga
     6361 aggcgaggag ctggcgctgc tctggcgcca cccggagcgc ctggtgacct tcttcatggc
     6421 ggccacgccg cccgcgctgc tggtgctgaa gatggccgtg gagggcctgt ccgaagaggc
     6481 cgtcgtccag gccaccggca tgtccgccgc ggacctccac gcggaggtcg tgcgcttcgc
     6541 gaaggacggc ctggtgctgg cgccggcatc ccgcattcac tgaagaacct gttgtcttcc
     6601 gagcggtttc gccgcagcac gtcaagacgc aagtgttctt catggatcct ttcgtgaaga
     6661 cgcatggcta ggtttgcgtc caacatcgcg cagaaaccga cccggaggtt ttcaccatga
     6721 agaagacgct gaccgccgtg ctgctgtcgc tgaccctcgc cgcgcccgtc atggccaagg
     6781 acatcgcggg tgtgaagtac ccggacaccg ccaccgtggc cggcaaggag ctgaagctca
     6841 acggcgtggg cctgcgcaag aaggccatct tcaaggtcta cacgctgggc ctctacgtgg
     6901 agaaccccac gcaggacgcc accgcgctgc tcaacgcgga cgaagtgaag cgcgtgcgca
     6961 tgttcatgaa gcgcgacctc aagaaggatc agatcaccga ggccatcgag aacggcttca
     7021 agaagagcgc gggcgcgaac atgcccaagc tccaggcgcg cctggacgcc ttcaaggccg
     7081 ccatccccgc ggaggtgaag gagggccagg agctcaacct cacctacgtg ccgggcaagg
     7141 gcaccaccgt gcaggtgacg ggcggccagt ccatcgacgt ggagggcaag gacttcgcgg
     7201 acgcgctctt ctccgtgtgg ctgggcaagg accccgtgga cggcggcctc aaggacggca
     7261 tcctcggcaa ggaggactga cgctccttca gtgcttcacc tggagtcctg cgcgcgcccc
     7321 cggagcgtcc cttcttcacg gaaggggcgt ttcgtggggc gccgtcgttt gcggaggcca
     7381 cgccattgct tcagtggtgg acagcggacg gtgcccctgt cacacgcgca ggagttgaag
     7441 ctggaatgcc cccgcgcatc aggggttgat gcgcgccgga ttctcacccc ttgtccgtgc
     7501 tggagaacgc tttgaagcga ctggccctct tcgccgcctc ctgtgtcctt ggcgccgcct
     7561 gcaagacggc ggagcccacc cccgagccgc cccaggccac caccccggcc cccgtggccg
     7621 ccgccgcgcc ggccacgccc gcgcccgagg cccccgccgt gcccatgtcc gagcgcccca
     7681 tgcccccggg cctggacgcc gcggtgatgg acccgtccgt gaacccctgt gacgacttct
     7741 accagtacgc gtgtggcggc tggctgcagg ccacggagat ccccgccgag cgcgcgcgct
     7801 ggagccgcgg cttcgaaacc gtcgccgagc gcaaccagac cgtgctgcgc gacatcctca
     7861 cgaaggccgc ggaagggcag ggcgagggca ccccggaaga caagaagctg ggggacttct
     7921 acggctcctg catggacgag gcgaagctgg agcagtcgct gcccacgctg cgcacgtacc
     7981 tggcgaagct caacgggctg aagagccagc aggcggtggc cagcgcggtg gcgtggctgc
     8041 acgcgcgcga cgtgaacgcg ctgttccgcg tggggtcgga tcaggaccag aaggacgcga
     8101 cgcaggtcat cgccatcgtg gacgccgggg gcctgggcct gccggaccgc gactactacc
     8161 tcaagcccga cgtgaagatg cgcgaggcgc gcaacgccta ccaggcgcac gtgcagaagg
     8221 tcttcgagtt gttgggtgac gcgcccttcg tggccagccg caaggccatc ggcatcctcg
     8281 ccatcgagac gcgcctggcc aacgcgcggc tgcccaagga ggagcggcgc gagccggaga
     8341 aggtctacca ccgcctggag cgccagggcc tgaagaagct ggcgcccgcc ttccagtggg
     8401 acacgtactt cgcggaggtg gggctgcccg cgggtgaagc gctcaacgtg acggagccga
     8461 agttcttctc ggaggtgtcc gcgctggtgc gtcagcagcg cccgacggac atggggccgt
     8521 acctctccta ccacctggtg aaggacgtgc agacggcgct gcccaaggcg ctgcgcgacg
     8581 agttcttccg cttcgagtcc tcggtgctca ccggcgccaa ggcggacctg gcgcgctgga
     8641 agaagtgcgt ggacgccacg gacgacgcgc tgccgcacgc gctggccaag cccttcatcg
     8701 cgcgcacctt cggcgcggat ggcaaggcca ccacgctgga catggtccag cagattgagc
     8761 agtccttcga gcgcaacctg gacacgctgt cctggatgga cgcggagacg aaggcgcagg
     8821 cgttggtgaa ggtgaagaag atcaccaaca agattggcta cccggaccag tggcgcagct
     8881 acgacgggct gacggtgacg cgcgactcgt acctggacaa cctgctggcg gcggacgcgt
     8941 tcgagcaggc gcgccagctg cgcaaggtgg gccagccggt ggaccgtcag gagtggttca
     9001 tgtctccgcc cacggtgaac gcctactaca acgcggccac caacgagatt gtgttcccgg
     9061 cgggcatcct ccagccgccg ttcttcgggc gggacgcgtc cgcggcggtg aacttcggcg
     9121 ccatgggcat ggtggtgggc cacgaaatca cccacggctt cgacgacgag ggccgccagt
     9181 tcgacgcgga cggcaacctg cgcacgtggt ggaccccggc gtcggacaag gccttccgcg
     9241 agcgcgtgtc gtgcgtgaag aaccagtatg accagtacac cgccgtggac gacgtgaagg
     9301 tgaacggcaa gctcaccctg ggcgagaacg tcgcggacct gggcggcctc aagctggcgt
     9361 acgcggccat ggaggcgtac ctggcgaagc acccggacca ggcggcgaag gcgaactcgt
     9421 accgcttcac cccggggcag cagttcttcc tcgcgcacgc gcaatcgtgg tgctcgaaga
     9481 ttcgtaacga ggctgcacgg cagcgggcgc tgacggattc gcactcgccg gcgttcctgc
     9541 gcgtgaaggg gccggacgtg aacctgccgc agttccagca ggccttctcc tgccccgcgg
     9601 gctcgccgat ggtggcgccc gctgcgaacc gctgtgaggt ctggtaaggc ttcggcccta
     9661 cctggaggac ggcatgtcta tctgctcgtg gctggtgttg ggcggtatcg cgggctggct
     9721 ggccagcatc atcaagggca ccaacgcccg gatggggatg ttcgccaaca tcttcgccgg
     9781 catcgtgggt tccatgctgg gcggctgggt gttcagcttc ttcggtggcc ggggcgtgac
     9841 gggcttcaac ctgtactcgc tgctggtggc cacggtgggc gccgtcatcc tgctgtccat
     9901 cctgcaagcc atccggaaat agcggtcccc tgaggtgggc cctggcggcg cggccgccgg
     9961 ggccttcagg gcgctggggg ctccttccgg ggcccgccgc ccgccgcctg ctggaactgc
    10021 atcacctggg caagcgcctt cgcgagccgt tccgaggcct gacccacctc cttcatgggg
    10081 ttgggcggca tccggcccgt gacgtccacc gggtgcagcg aggcgaggaa tgccgggagg
    10141 tcatcgcccg attccatccc gcttcgcagc tggaggatgt cgcccttggc gtcgtagaag
    10201 gccgccagcg agaggttgtc gcggtaggcc tgcagcagca cccgcaccag gaacagcacc
    10261 agcacggtga tggtgatgcg cagggagagc acgccaacgt ccaccatgta gctccggttc
    10321 acctggttca gccggtcgat ctccgccttc atcgcgagga ctgcttcctg ccgttgggtc
    10381 tcctggctgt tgacgttctg gagcgcctga tcgaccagga tgagcttgtt gatgatgaac
    10441 tggccatatt ccttcaggag gaccctgccc gccggttcga tttccctgcg ggccagcctg
    10501 agctgctcct gggcttccga cagctcgcga ttgagggtgg aggccgtcac ggcaggccgg
    10561 ggctggatga tgtcctgggc gagcacgaag atggccagcg cggcggagat ggacgcgatg
    10621 accagcgtca ggaagagcca cgcaagcctg cgcagattct ccgcgcgctg ccgcaggttg
    10681 cggatgacct gctggacgac cggatccttg ctgcgcgtga gcggctcggt gtccgggcgg
    10741 ggcagcagga agaacgtcat gatggcgagc gcgcccagca tggcgcccac ccacagcgag
    10801 agcccccggg catagcggag gtccagctcg ttcaagaggg agaaggcca
//
