LOCUS       NC_018681              21107 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6295773
            Orig. end                         :: 6316880
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="38"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11107
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    299..313
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(840..851)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            1374..1940
                     /locus_tag="O3I_RS27735"
                     /old_locus_tag="O3I_027585"
     CDS             1374..1940
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944970.1"
                     /locus_tag="O3I_RS27735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027585"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_014986321.1"
                     /transl_table=11
                     /translation="MPKVSEDHLAARRSQILDGARRCFAEYGYEGATVRRLEEEIGLSR
                     GAIFHHFRDKDALFLALAQEDAERMADVAANQGIVQVMRDMLTHPEQFNWLGTRLEIAR
                     RLRTDPEFRAGWTQRSAELTAATLARLERRKAAGALRDDVPTDVLLGYLDLVLDGLIAR
                     IASGHTNENLTAVLDLVEASVRRRD"
     gene            complement(1947..2741)
                     /locus_tag="O3I_RS27740"
                     /old_locus_tag="O3I_027590"
     CDS             complement(1947..2741)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350850.1"
                     /locus_tag="O3I_RS27740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027590"
                     /product="hypothetical protein"
                     /protein_id="WP_014986322.1"
                     /transl_table=11
                     /translation="MIDIITLRGTGEPRNPDGTPAGMLYAVTALLDTARFSAFEPDWPA
                     SVGPSPDLWGPSLDTSVRLGTAAGVKAIQDSPNVCGLLSYSLGGICASRILEGVRSGKY
                     KNTNGSPLEIAFAVNISNPLRKAGESVGNLCPANTFGLHGQRGLWPAGVAIREYANPGD
                     IITAAPADSPLRIIDVGISPFSFLEGARIGNFGPLIFAELLAWLMNDPVTNLNRYATAV
                     HGVIGYLTPWPEGQHVLYSSHEMPGTDVLWTTHAAEYLNDNF"
     gene            complement(2919..3740)
                     /locus_tag="O3I_RS27745"
                     /old_locus_tag="O3I_027595"
     CDS             complement(2919..3740)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.4"
                     /locus_tag="O3I_RS27745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027595"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_014986323.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.2e-05, bitscore:
                     21.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEFSSGDRTVLVTGVDERLGYATAKRLAADGAAVIVHAQDKELA
                     DDAVQRLVAAGADAGRLRAVHADFTELAEVDELGGTLAATVRRLDAVVNAAAVPGPQRR
                     GRTRAGHESTLQVNYLAPQRLTMALAAAVAAANGRIVNVSSRLHSAGNIDYSDLDRNRA
                     IYTPLAVYAQSKLALTMFTRSLAETGPAGLTAVGVSPADFEIDMPQLRSHASAPLDAAA
                     DLLATLSDPHTTVVNGGYYDGIDESKPAALVRNSRARARLAAWTAALGPAA"
     gene            complement(3886..4032)
                     /locus_tag="O3I_RS45680"
     CDS             complement(3886..4032)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS45680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_167829183.1"
                     /transl_table=11
                     /translation="MTATPGRAHALRALPLGVAWCADPVLPSALERVGFGSEDEPPSSV
                     AAV"
     gene            4307..4723
                     /locus_tag="O3I_RS27755"
                     /old_locus_tag="O3I_027600"
     CDS             4307..4723
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350849.1"
                     /locus_tag="O3I_RS27755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027600"
                     /product="thioesterase family protein"
                     /protein_id="WP_014986324.1"
                     /sec_met_domain="4HBT_2 (E-value: 8.2e-24, bitscore: 83.3,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFSIPIVVRGYELDTQGHLNQAVYLQYTEHARWEMLRAAGLPQD
                     KLIATGVGPVVLESTIKYLRELRGGDEVTVDTDIEYSGGKTFTFRHEIRKLDGTVAAEA
                     RVVGGLLDLRERKLVAGPAERFRDLAERPDLLGL"
     misc_feature    complement(4951..4963)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     gene            5031..5447
                     /locus_tag="O3I_RS27760"
                     /old_locus_tag="O3I_027605"
     CDS             5031..5447
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350848.1"
                     /locus_tag="O3I_RS27760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027605"
                     /product="hypothetical protein"
                     /protein_id="WP_237748142.1"
                     /transl_table=11
                     /translation="MPPLHGLLVAESERDISVRVAEGTWTFRRSDVLRVLDSAVPEGVR
                     AERGARPVLVDIRVGATADFTRRLRIDVVDRPMTMQQAPSAALGDEQLRELTESWADRL
                     NLVDLPGTNGATFTYCQTKSLATSDDGINCDSLD"
     gene            5492..6421
                     /locus_tag="O3I_RS27765"
                     /old_locus_tag="O3I_027610"
     CDS             5492..6421
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019047729.1"
                     /locus_tag="O3I_RS27765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027610"
                     /product="hypothetical protein"
                     /protein_id="WP_014986326.1"
                     /transl_table=11
                     /translation="MSESDDLHATAMAATLREFHGLSAIQLDLRDFPRESGSFRLDRYG
                     TARSVSHLIGLDDVRSVWWRRPHPTQPPAGVRVSDNDFRQAECDGFIQGLLWSIPAHWV
                     NDPGADRTAARKIVQLETALRAGFAVPETLITNDPDEARSFAESRPGPVVYKRTGTSRA
                     EFAETRIITEHDYDRLAGIRAAPTTFQDYVDAECDLRVVWVDGVEWTVRIDSQAGVGRV
                     DSRLDTSVDFVPEHLPASVSKSLATLMGALGLSFGVLDIRLGLDGEYYFLEVNPQGQFA
                     YLEIKTGLPIFRSLANLLVDGDGAVEGY"
     gene            complement(6415..6972)
                     /locus_tag="O3I_RS27770"
                     /old_locus_tag="O3I_027615"
     CDS             complement(6415..6972)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013989.4"
                     /locus_tag="O3I_RS27770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027615"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_041564459.1"
                     /transl_table=11
                     /translation="MLQTMVTLDGYAAGPDGALDWIEADDSALDDYLAGLLRGVAAQVY
                     GRASYELLAQYWPGAQQNPATPGDAMLAPLVNGLPKLVLSSDPQVALPWQPARRIGGNL
                     AGEIDELKSEDGRPIIVFAGVRTAQEFLRQDAVDELRLLVFPVLLGEGRRLFDGVPAQR
                     LHLVDAEPFPKSGVVLHTYRRQ"
     gene            complement(7103..7336)
                     /locus_tag="O3I_RS27775"
                     /old_locus_tag="O3I_027620"
     CDS             complement(7103..7336)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210020.1"
                     /locus_tag="O3I_RS27775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027620"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_014986328.1"
                     /transl_table=11
                     /translation="MSDRPAQVKATLGKGTRVTGKSRDRLQTQLKKQYEAGASIRSLAR
                     ATGRSYGFIHNVLVESHVQLRSRGGANRRKSQ"
     misc_feature    7407..7422
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            complement(7418..9049)
                     /locus_tag="O3I_RS27780"
                     /old_locus_tag="O3I_027625"
     CDS             complement(7418..9049)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011559842.1"
                     /locus_tag="O3I_RS27780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027625"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_014986329.1"
                     /transl_table=11
                     /translation="MITATDLEVRAGVRTLLSAPGPALRVQSGDRIGLVGRNGAGKTTT
                     LRILAGEGEPYAGKILRSSDIGYLPQDPREGNLDILARDRVLSARGLDTLIRDMEKQQA
                     LMAEVADENEREKAVRKYGRLEDRFSALGGYVAESDAARICHSLGLPDRVLGQALRTLS
                     GGQRRRIELARILFAASDGSGGRSDTILLLDEPTNHLDADSITWLRGFLQNHDGGLIVI
                     SHDVELLGDVVNKVWFLDAVRGEADVYNMGWQKYLDARATDEQRRRRERANAEKKASAL
                     RVQAAKLGAKATKATAAQNMAKRADRLMAELDDVRVADKVARIKFPEPAPCGKTPLMAE
                     NLTKMYGSLEIFAGVDLAIDRGSRVVVLGLNGAGKTTLLRLLAGVEQPTAGSLVPGHGM
                     KVGYFAQEHDTLDDNATVWENIRHAAPDAGEQDLRGLLGAFMFTGPQLDQPAGTLSGGE
                     KTRLALAGLVSSAANVLLLDEPTNNLDPVSREQVLDALRTYAGAVVLVTHDPGAAEALS
                     PERVILLPDGTEDHWSADYLELIQLA"
     gene            9211..9996
                     /locus_tag="O3I_RS27785"
                     /old_locus_tag="O3I_027630"
     CDS             9211..9996
                     /NRPS_PKS="Domain: PKS_KR (15-179). E-value: 3.9e-07.
                     Score: 22.1. Matches aSDomain:
                     nrpspksdomains_O3I_RS27785_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013806708.1"
                     /locus_tag="O3I_RS27785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027630"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_014986330.1"
                     /sec_met_domain="adh_short_C2 (E-value: 6.8e-32, bitscore:
                     110.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSERNNGTATDLVGKSALVTGASRGIGKAVAAELLSRGANVLISA
                     RKKDPLEEAAAELRALGHQGEVVALAGNSGHAEDRAASIDRMMAEFGSVDILINNTGIN
                     PVFGSLMEADLDAVRKIFDVNVVAALGFVQLAYKAWMGAHGGAVVNVASVAGLRSSGVI
                     AAYGASKAALIRLTDELAWQLGPKIRVNAVAPGVIKTKFADALYSADEERAASVYPLKR
                     LGTPEDVARLIGFLVSDEAAWITGETVRVDGGLLSTGGL"
     aSDomain        9256..9747
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS27785_PKS_KR.1"
                     /evalue="3.90E-07"
                     /label="O3I_RS27785_PKS_KR.1"
                     /locus_tag="O3I_RS27785"
                     /protein_end="179"
                     /protein_start="15"
                     /score="22.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="SALVTGASRGIGKAVAAELLSRGANVLISARKKDPLEEAAAELRA
                     LGHQGEVVALAGNSGHAEDRAASIDRMMAEFGSVDILINNTGINPVFGSLMEADLDAVR
                     KIFDVNVVAALGFVQLAYKAWMGAHGGAVVNVASVAGLRSSGVIAAYGASKAALIRLTD
                     E"
     CDS_motif       9262..9336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS27785_0001"
                     /evalue="6.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="O3I_RS27785"
                     /protein_end="42"
                     /protein_start="17"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LVTGASRGIGKAVAAELLSRGANVL"
     gene            10001..11107
                     /locus_tag="O3I_RS27790"
                     /old_locus_tag="O3I_027635"
     CDS             10001..11107
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210023.1"
                     /locus_tag="O3I_RS27790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027635"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_051066776.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 4.6e-44, bitscore:
                     150.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVVVCGLGPAGRALAHRCLVRGLTVTVVDPAPERGWHATYAAWA
                     DELPDWLAADAVAATVAQPKAWGTRGHRIDRPYTVLDTARLRDSLDVTGARIIADRAVE
                     CGPGAAVLASGTVLRGCRVIDARGIGRSPALAEQTAYGLMLDRDRCPDIEPMFMDWRPD
                     NGASADAPRSFLYAVPLGGDTMLLEETCLVGRPALDGRELRDRLLHRLRSRGIEVTGDE
                     RVERVRFPVEGGRPGRNTFGAAGGFAHPATGYSVAAALAAADTVALGAAAWPVSARAVY
                     RLRAAGLRALLHLPTTDLPVFFDAFFTLPPAAQRAYLSGRTDLNGTVRAMLGLFGTLPR
                     PVRRRVAAATLGTPIRSRIRIPSAIMEE"
     misc_feature    10880..10882
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11196..12125
                     /locus_tag="O3I_RS27795"
                     /old_locus_tag="O3I_027640"
     CDS             11196..12125
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020110104.1"
                     /locus_tag="O3I_RS27795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027640"
                     /product="Ku protein"
                     /protein_id="WP_014986332.1"
                     /transl_table=11
                     /translation="MRSIWKGSIAFGLVNVPVKVYTATEDHDIRFHQVHAKDGGRIKYD
                     RVCTVCGKSVQYADIDKAYESPDGDKVILTDEDFAKLPAAEKHEIPVLQFVPSEQIDPI
                     LYEKSYYLEPDSSTPKAYVLLATTLERIDRTALVHFTLRQKTRLAALRVHEGVLVLQTL
                     LWPDEVREVEFESLDGVAEPKPQEIKMAETLVETMSDDFDPDQFTDEYQIELKRLLDEA
                     IASGTGKVPEQPESAPAEMDAEVVDLVAALQRSLEASGRRSTAEDNGKDAPAKKTAKKA
                     AAKKTPAKKAAKKTADKPAKKTAARKGA"
     gene            12160..12717
                     /locus_tag="O3I_RS27800"
                     /old_locus_tag="O3I_027645"
     CDS             12160..12717
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350576.1"
                     /locus_tag="O3I_RS27800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027645"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_036561517.1"
                     /transl_table=11
                     /translation="MDSAVVIVPMGLGHLRQVLDLGHEVFDITTKPYTSWSLTSVAEHL
                     DSPDNACWVALDSDRVVGFVLGSMEFENRDDWAYLEWIAVAPDMQGHGIARRLVDVCSE
                     ALFARGARRIVTDVEDRNAASTALMTRSGFTPAATVTLFVRPNPDDPDPDSQLDAAAIA
                     PGTKRALIRRGRLAGDNHRAAR"
     gene            complement(12935..13552)
                     /locus_tag="O3I_RS27805"
                     /old_locus_tag="O3I_027650"
     CDS             complement(12935..13552)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019926923.1"
                     /locus_tag="O3I_RS27805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027650"
                     /product="hypothetical protein"
                     /protein_id="WP_141691757.1"
                     /transl_table=11
                     /translation="MDEQMYERSRRGLHAVAELLIAGPQYRQYETIRLRVVHQGFGGVR
                     WPVSVVGAELVWPEGRAALAGTYRELGKLANIEPGAPDGLYKDTTGVEPDSAMDIDPVA
                     AQQISDWFALGDKALRCLAPDSTPVLWPEHFDLSSAIGEVNYGVSPGDSAHPGPYAYVG
                     PWTPRTGVFWNAPFGALRPSTEFDSAASLLAFFEEGRAQAAG"
     misc_feature    complement(13196..13198)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13598..13963)
                     /locus_tag="O3I_RS27810"
                     /old_locus_tag="O3I_027655"
     CDS             complement(13598..13963)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS27810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_027655"
                     /product="hypothetical protein"
                     /protein_id="WP_141691756.1"
                     /transl_table=11
                     /translation="MEERVAVLEGKWHRTEGDGIAYQEAIIDTRDRVVRLEHSMSTLKV
                     MAGHTQIRLGAVEEDVAGLKQDVAFLKGDVSGLKQDVSGLKRDVSGLKQSMSGLTRSVD
                     AIVSHFGIALPAEEAQP"
     gene            14225..15262
                     /locus_tag="O3I_RS27815"
                     /old_locus_tag="O3I_027660"
     CDS             14225..15262
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007239025.1"
                     /locus_tag="O3I_RS27815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027660"
                     /product="2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein"
                     /protein_id="WP_014986336.1"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 1.9e-17, bitscore:
                     62.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFHVPIIDISPYVEGGDAAARAAVARQVDEAASTVGFMQIRGHG
                     IARPVLDEFAAALDDFFALAPATKESYRTAVEFNRGYSPPKSESLSLSLGVASATRMND
                     FFEAFNIGTTTADYPGLDLPAQAGYADNVWPAELPDFRPRVQRYYAEAARVAGTLTTVF
                     ADALDLPAGYFESFTDHSLNVLRMNNYALPPGSVDLDGDLKGMGEHTDYGIVTVLWADQ
                     VPGLQVLGADGRWHDVQPADEALLVNLGDVMARWTNERWLSTLHRVMPPIVDGTIERRR
                     SAAFFHDGNFDAVIETLPSCVGAGSKYPPITVSEHVQAKLAGSRALQPNTNAHREAARV
                     LSARD"
     misc_feature    14900..14902
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15269..16135)
                     /locus_tag="O3I_RS27820"
                     /old_locus_tag="O3I_027665"
     CDS             complement(15269..16135)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007620143.1"
                     /locus_tag="O3I_RS27820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027665"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_014986337.1"
                     /transl_table=11
                     /translation="MRLMHRLLVIPILSALAVTTMSCGAKHDDGVIRIGVNDLAEPHWD
                     VYKKKAADQGIRVEFINFTDYNQPNPALAQRRIDLNKFQHVRYLANYNARNNDTLVPVG
                     ATEIFPLTLYSRKHKSVAEIPQGGQITLSNNPANQVRPLLSLAAAGLVVLKGGASWDSK
                     LEDVDTAASKVKLTPIDPTLTAQSLSSVDAAFVDDTFARPAGLTKNDTIYTDDPERPEL
                     KQYINIFAARAADKDNPTLLKLAELYHDPEVEAAVRAETGYEGIFKTNTPADLQATATE
                     LEAKFRK"
     gene            16270..17145
                     /locus_tag="O3I_RS27825"
                     /old_locus_tag="O3I_027670"
     CDS             16270..17145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016882930.1"
                     /locus_tag="O3I_RS27825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027670"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_014986338.1"
                     /transl_table=11
                     /translation="MKFHRVLAIPVLVATAALTVTACGSDDKSASDTVVRIGTTDKDKA
                     WDVFEQRAKDKGITLKITNFSDYKQPNLALSQKQIDVNLFQHLQFLGAYNVANKDTLTP
                     IGSTYIVPLGLYSKKHKALAGLPQGAEIAIPNDPTNQARALFVLQAAGLLKLSGSSSAP
                     TAADVDKGASKVKVTTVDAAQTALSLASVDGAVINNTFLDRSGIDPDSALYKDDPKNPS
                     AEPYINALVTRAEDKNNPKLLQLVELWHDPEVQRAHAEVTKNTAVEVRRTGPELEQILQ
                     RVQQTIRDGK"
     gene            17142..18155
                     /locus_tag="O3I_RS27830"
                     /old_locus_tag="O3I_027675"
     CDS             17142..18155
                     /EC_number="7.4.2.11"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0048473 - D-methionine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210945.1"
                     /locus_tag="O3I_RS27830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027675"
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="WP_014986339.1"
                     /transl_table=11
                     /translation="MSDNPPAVEFRSVTKVFGKGADAHIALDDIDLRIEQGEIFGVIGY
                     SGAGKSTLVRLINALERPTSGTIEVAGNPITGVREAEVRRLRRDIGMVFQQFNLFRSRT
                     AAGNVEYPLKVAGWKRAARKARVAELLEFVGLSDKARSYPDQLSGGQKQRVGIARALAT
                     SPSLLLADESTSALDPETTAEVLRLLKKVNRELGVTIVVITHEMDVIRAVADRVAVLAE
                     GRIVELASTFEVFATPQAAPTQSFVATVLHNRPSEDEVRRLGELHGGRLVTVDVDDEHG
                     IGAALTVAAHADVRFEVVYGGVGTLQNKTFGSVTLALHGADDAVDKVIAELGPRTA"
     gene            18167..18829
                     /locus_tag="O3I_RS27835"
                     /old_locus_tag="O3I_027680"
     CDS             18167..18829
                     /EC_number="7.4.2.11"
                     /GO_function="GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0048473 - D-methionine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005057738.1"
                     /locus_tag="O3I_RS27835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027680"
                     /product="methionine ABC transporter permease"
                     /protein_id="WP_014986340.1"
                     /transl_table=11
                     /translation="MQADWDKLRPLLTEAIGTTIYLVLITFVIGGLIGLFLGTVLYTTR
                     KGGLLANAPINLLLNVIVNVVRPIPFIILLAALGPVTLEVVGTTIGRDAAAFVMIVAAS
                     FGIARIVEQNLVTVDPGVIEAARAVGAGPLRIIVTLLIPEALGPLILGYTFVVISIVDI
                     SAMAGTVGGGGLGDFALVHGYQQFNWQVTFVATLIIVAGVQGIQFFGNWLARKVLRR"
     gene            complement(18874..19320)
                     /locus_tag="O3I_RS27840"
                     /old_locus_tag="O3I_027685"
     CDS             complement(18874..19320)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025197.4"
                     /locus_tag="O3I_RS27840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027685"
                     /product="DUF4189 domain-containing protein"
                     /protein_id="WP_014986341.1"
                     /transl_table=11
                     /translation="MKYTAGKAVLGLFASTTVAFVAAGAGQAHAEPGPDGSYYGSRAIT
                     VDANGASVSTAWNYPNWAESDAAALDDCRAKGGRNCTIIVRFVDGCGAIAERDGRYVGG
                     TGPNRAEAERAALAAFGPPPVNFGSSAPSAARIVGTTLCTSNVE"
     misc_feature    complement(19434..19446)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.2"
                     /tool="antismash"
     gene            complement(19472..19897)
                     /locus_tag="O3I_RS27845"
                     /old_locus_tag="O3I_027690"
     CDS             complement(19472..19897)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210087.1"
                     /locus_tag="O3I_RS27845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027690"
                     /product="DUF4189 domain-containing protein"
                     /protein_id="WP_014986342.1"
                     /transl_table=11
                     /translation="MSNLGRAAFGAVLASTAALTIVGAGSAGAAPDYHGTLAFSPSTGK
                     VVGSVDQPSWVTADAVAIRDCGVYDCKILVRFSNGCAAAVRGADGAFAADWAATREEAE
                     RLAIAKLGETAPPFPDLGSAVPQPARVVLSSCTKNAS"
     gene            complement(20037..20816)
                     /locus_tag="O3I_RS27850"
                     /old_locus_tag="O3I_027695"
     CDS             complement(20037..20816)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350617.1"
                     /locus_tag="O3I_RS27850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_027695"
                     /product="ESX secretion-associated protein EspG"
                     /protein_id="WP_014986343.1"
                     /transl_table=11
                     /translation="MVELRFTGLEFQLLWHAYGRDRLPYPLQFRPQAVDFADLVAQREA
                     AAAALLDRHSIELERALQILLEPEVRIELKGFGAPELTRIFRFHGAVRDAAAATLVQLP
                     GVAADTGGAVTLRYGPAAQVAADAVGALPDTPPGTHPPLEARRAEITADRERPVREAYA
                     VGLAQRFDRLFKRERRALGEITVLPGPAVDARPTFGRGFWWMDYPDGRYYVQTGDPVVA
                     KPMDSAAMAAEIRRLTVLTQRYYREDREHDEYLRTRR"
ORIGIN
        1 cgggctcgca ggtcgtctcc gactactatg agaaggcggg cctgtggccc tacctggaga
       61 agctcggctt cttcgtgggc ggttacggct gcaccacctg catcggcaac accggcccgc
      121 tgccggacga gatctccaag gcgatcaacg acaacgacct ctcggtcacc gcggtgctct
      181 ccggcaaccg taacttcgag ggtcgcatct cccccgacgt gaagatgaac tacctggcct
      241 cgccgccgct ggtcatcgcc tacgcgctcg cgggaacgat ggacttcgac ttcgagtccg
      301 acccgctcgg ccaggacacc gacggcaacg acgtgttcct gaaggacatc tggccgtccc
      361 cgcaggagat cgacgacacc atcaagtcgg cgatcagccg ggacatgttc accaagtcct
      421 acgccaccgt cttcgagggc gacgagcgct ggaaggggct gagcaccccc gagggcgaca
      481 ccttcgcgtg ggacgagagc tcgacctacg tccgcaaggc gccgtacttc gacggcatgc
      541 agatggagcc gagcccggtc gaggacatca agggcgcccg cgtgctcgcg ctgctgggcg
      601 actcggtcac caccgaccac atctccccgg ccggcccgat caagccgggc accccggcgg
      661 cgcagtacct cgactcgcac ggcgtgcagc gcaaggacta caactcgctg ggctcgcggc
      721 gcggtaacca cgaggtgatg atccgcggca cgttcgccaa catccggctg cgcaaccaac
      781 tgctcgacga cgtctcgggt ggttacaccc gcgacttcac ccaggacggt ggcccgcagg
      841 cgttcatcta cgacgcctcg cagaactacc aggccgcggg catcccgctg gtcgtgctgg
      901 gcggcaagga gtacggctcg ggttcctcgc gcgactgggc cgccaagggc acctcgctgc
      961 tcggcgtgaa ggccgtgatc accgagtcct tcgagcgcat ccaccgctcc aacctgatcg
     1021 gcatgggcgt catcccgctg cagttcccgg ccggcgagtc cgccgcgtcg ctgaagctgg
     1081 acggcaccga gaccttcgac atcgagggca tcaccaagct gaacgagggt gcgactccga
     1141 agaccttgaa ggtgaccgcc accaaggaga acggcgagaa ggtgagcttc gacgcggtgg
     1201 tccggatcga cacccccggt gaggccgact actaccgcaa cggcggcatc ctgcagtacg
     1261 tgttgcgcaa catgattcgc ggctgatctc gcatctgccg tacgtcgagg atccgcgcac
     1321 cgcgttttcg cggtgcgcgg acttctcaca cctcctggag gagcacgccc gacatgccca
     1381 aagtcagtga agatcatctc gccgcccggc ggagccagat tctcgacggg gcgcggcgct
     1441 gctttgccga atacgggtac gagggcgcca cggtgcgccg cctcgaggaa gagatcgggc
     1501 tgtcccgggg tgccatcttc caccacttcc gggacaagga cgcgctgttc ctcgcgctcg
     1561 cgcaggagga tgccgaacgg atggccgacg tcgcggccaa ccagggcatc gtccaggtca
     1621 tgcgcgacat gctcacccac ccagagcaat tcaactggct cggcacccgg ctggagatcg
     1681 cccggcggct gcgcaccgac ccggagttcc gcgcgggctg gacccagcgc tcggccgaac
     1741 tcaccgccgc caccctggct cgcctggaac gccgcaaggc ggcgggcgcg ctgcgcgacg
     1801 acgtccccac cgacgtgctg ctcggctacc tcgacctggt gctcgacggc ctgatcgcgc
     1861 gcatcgcctc cggccacacc aacgaaaacc tcaccgccgt actggatctc gtcgaagcct
     1921 cggtgcgccg ccgggactga ggccgttcag aagttgtcgt tgaggtactc ggcggcgtgc
     1981 gtcgtccaca gcacatcggt gcccggcatc tcgtggctcg agtacagcac gtgctgcccc
     2041 tccggccacg gcgtcagata gccgatcacg ccgtgcacgg ccgtggcgta gcggttcagg
     2101 ttcgtcaccg gatcgttcat caaccaggcc agcagttccg cgaagatcag cggcccgaag
     2161 ttgccgatcc gcgcgccctc caggaacgag aacggcgaga tgccgacgtc gatgatgcgc
     2221 agcggcgaat ccgcgggcgc ggccgtgatg atgtcgccgg gattggcgta ctcccggatc
     2281 gccacgcccg ccggccagag gccacgctga ccgtgcaggc cgaaggtgtt cgccgggcac
     2341 aggttcccca ccgattcgcc cgccttgcgc agcgggttgg agatgttcac cgcgaacgcg
     2401 atctccagcg gcgagccgtt ggtgttcttg tacttacccg agcgcacccc ttccaggatg
     2461 cggctggcac agatcccgcc gagcgaataa ctgagcagcc cacacacatt cggcgaatcc
     2521 tggatcgcct tgacgcccgc cgcggtgccg agtcgcaccg aggtgtccag cgacgggccc
     2581 cacagatccg gcgacggacc gaccgaagcg ggccagtccg gttcgaaggc cgagaaccgt
     2641 gccgtgtcca gcagtgcggt gacggcgtac agcatgcccg cgggcgttcc gtccggattg
     2701 cgcggctcac cggtaccgcg cagggtgatg atgtcgatca tcagtgatct ccttgcacac
     2761 gcgccgcgtc atccggcgca taaccccacg gtatgcccgt tacggagccg aagggcgagt
     2821 accggactac ccgatttcac cgagcgaacc gggcgccccg tacgcggccg ccgccggccg
     2881 attcccggta tggcggctcg cgtacgaggc ggtacgcatc aggcggcggg gccgagcgcg
     2941 gcggtccacg ccgcaaggcg cgcacgggcg cgcgagttgc gcaccagcgc agcgggtttc
     3001 gattcatcga taccgtcgta gtagccgccg ttgacgaccg tggtgtgcgg atcgctcagg
     3061 gtggcgagca agtcggccgc ggcgtccagc ggcgcgctcg cgtggctccg caactgcggc
     3121 atatcgatct cgaaatcggc cgggctcaca ccgacagcgg tcagcccggc cggaccggtc
     3181 tcggcgagcg agcgggtgaa catcgtcagc gccagtttgg actgggcgta caccgccagc
     3241 ggcgtgtaaa tagcgcgatt gcgatcgagg tccgaatagt cgatattgcc cgccgagtgc
     3301 agccgcgacg acacgttcac gatccggccg ttcgccgccg cgaccgccgc ggccagcgcc
     3361 atggtgagcc gctgcggcgc gaggtagttg acctgcaagg tcgactcgtg tccggcgcgc
     3421 gtgcgtccgc gtcgttgcgg gccgggcacg gcggcggcat tgaccaccgc gtcgagcctg
     3481 cgcaccgtcg cggccagcgt cccgccgagt tcgtcgacct cggccagctc ggtgaaatcc
     3541 gcgtgcaccg cgcgcaggcg gccggcgtcc gcgccggcgg ccaccaaccg ctgcacggcg
     3601 tcgtcggcga gttctttgtc ctgcgcgtgc acaatcacgg cggcaccatc ggcggccagg
     3661 cgcttcgccg tcgcataacc gaggcgttca tcgacgccgg tcaccagcac ggtccggtcg
     3721 ccggacgaga attcgggcac agctctccca tcgggtggtc gcgcgcgtca cggtgcgacc
     3781 ggcgacgcac gcgggaacga ctccgcgatc cgcgatcacg gagagaaacg cacggccaac
     3841 cgtgcgcgga acgcgacgcg gccgaggacg gccggcgcgc ggaaatcaga ccgcggccac
     3901 cgaactcggc ggctcgtcct cactgccgaa cccgacccgt tccaaggcgg acgggagcac
     3961 cgggtcggca caccaggcaa ccccgagggg cagcgcgcgc agtgcgtgcg cacggccggg
     4021 agttgcggtc atcgctcgat ccaaccgacc cgcgccgttg ccgcacaagg catccggcgc
     4081 cgatttgacg attccctagc gatccgccgg gcagccgtgc gatccagccg agttcgaggt
     4141 ggatccgcgg ggcacgggtg ccacgcccgg cgttcggcgc acctgatcac ctttcgccga
     4201 ctccgcgcca tcgaccgcag agaccgaggt cagcagcggc gccggtgtga cgaaggcatc
     4261 ggcccggttc gggaacaaga ccaacaggta cggtgctggt ccagacatga ccttcagcat
     4321 cccgatcgtt gtgcgcggct acgagctcga tacgcaaggc cacctgaacc aggcggtcta
     4381 tctgcagtac accgagcacg cgcggtggga gatgctgcgg gccgcgggct tgccgcagga
     4441 caagctgatc gcgacggggg tgggtccggt cgtgctggag tccaccatca agtacctgcg
     4501 ggagctgcgc ggcggcgacg aagtcacggt cgataccgat atcgaatact ccggcggcaa
     4561 gaccttcacc ttccggcacg agatccgcaa actcgacggc accgtcgcgg ccgaggcgcg
     4621 ggtggtcggc ggcctgctcg atttgcgcga acgcaagctg gtggccggac ccgccgaacg
     4681 tttccgggac ctcgccgagc ggcccgacct gctcggtctg tgaaatcgca cgtgcgaatg
     4741 cacagccgcc aatccggggc tatgcgagag acacattgcc attcggaaat agctcgttga
     4801 ttgcgccgga actattggtg ccctgccgaa aaactttcgg cgctagtgca tccgggatcg
     4861 taatccggtt tgccaccggg ggttaaatct gccgatccgg accggtaccg gcccttcgca
     4921 cgttatgatc gggctcacgc tcgggggtcg tggcaaatcg cgagcagatc ggagaaatgg
     4981 ctatgaccga cgcactccgc ctccacggaa ccgcgccgaa gagtgatcgt gtgcctccgc
     5041 tgcacgggct gttggtagcg gagtcggaac gagatatcag cgtgcgcgtc gccgagggaa
     5101 cgtggacctt ccgtcggtcc gacgtgctgc gcgtgctcga ttcggcagtg cccgaggggg
     5161 tacgcgccga gcgcggcgcc cggccggtgc tggtcgacat ccgggtcggc gccaccgcgg
     5221 atttcacccg tcgcctgcgc atcgacgtgg tcgaccgccc gatgaccatg cagcaggccc
     5281 cgtccgcggc gctcggcgac gagcagctgc gcgagctcac cgaatcctgg gccgatcggc
     5341 tgaatctggt ggacctgccc ggcaccaacg gcgccacctt cacctactgc cagaccaagt
     5401 cgctcgccac cagtgacgac ggtatcaact gcgacagtct cgactgagcg gcgcattcat
     5461 ggcgggacgc cggacgggtt cagtcctcat cgtgtccgaa tccgacgatc tgcacgctac
     5521 cgccatggcg gcgacgctgc gagaattcca cgggctcagc gcgattcagc tcgacctgcg
     5581 cgactttccg cgtgagtcgg gcagtttccg gctggatcgc tacggtaccg cccgttcggt
     5641 ctcccacctg atcggcctgg acgacgtccg ctcggtctgg tggcgccggc cgcatccgac
     5701 tcagccgccc gccggagtcc gcgtctccga caacgacttc cggcaggccg aatgcgacgg
     5761 attcatccag ggtctgctct ggtccatacc ggcgcactgg gtcaacgacc cgggggcgga
     5821 ccgcaccgcc gcccgcaaga tcgtccaatt ggagacagcg ctgcgggccg gtttcgcggt
     5881 gccggagacg ctgatcacca acgacccgga cgaggcccgc agcttcgccg aatcccggcc
     5941 cggcccagtc gtttacaagc gcaccgggac cagccgcgcc gagttcgcgg aaaccaggat
     6001 catcaccgag cacgactacg acagactggc cggcatccgc gcggcgccga ccaccttcca
     6061 ggactacgtc gacgccgaat gcgatctgcg ggtggtctgg gtggacggcg tcgagtggac
     6121 ggtgcgcatc gactcccagg cgggcgtcgg ccgggtcgac tcccgcctgg acacctcggt
     6181 cgatttcgtg ccggagcatc tgcccgcctc ggtcagcaaa tcgctcgcca ccctgatggg
     6241 cgcgctggga ttgtcgttcg gcgtcttgga cattcggctc ggcctcgacg gcgagtacta
     6301 cttcctcgag gtcaacccgc agggacagtt cgcatacctg gagatcaaga ccggcctgcc
     6361 gatcttccgc agcctggcca atctgctcgt cgacggggac ggcgccgtcg agggctactg
     6421 acgccgatac gtgtgcagca ccacaccgga tttcgggaac ggttccgcgt cgaccaggtg
     6481 cagtcgctgt gcggggaccc cgtcgaacag ccgccgcccc tccccgagca acaccggaaa
     6541 caccagcagc cgaagctcat ccaccgcgtc ctggcgcagg aactcctgcg cggtgcgcac
     6601 gccggcgaac acgatgatcg gccgaccgtc ctcgctcttc agctcatcga tctccccggc
     6661 gagattcccg ccgatccggc gcgcgggctg ccagggcagt gcgacctgcg ggtccgacga
     6721 cagcacgagt ttcggcagac cgttcaccag cggagccagc atcgcgtcac ccggtgtcgc
     6781 cggattctgt tgcgcgcccg gccaatactg ggccagcagc tcgtaggacg cgcgcccgta
     6841 gacctgggcg gccaccccgc gcagcagtcc ggccagatag tcgtccagtg ccgaatcgtc
     6901 ggcctcgatc cagtcgagcg ccccgtccgg acccgccgcg tagccgtcca gcgtcaccat
     6961 tgtctgcagc atgatcgtcc gcactgtcga ggctcctggt cgtgagagtt gtgcttcgac
     7021 aatgcagacg gcgagccgcg cggaaactca ccggttcagg cgaaatccgt tccgccgaaa
     7081 ccggttcgag ccggctgcgg tgctactgac tcttgcggcg gttcgcgccg ccacggctgc
     7141 ggagttgcac gtgcgactcc accagtacgt tgtggatgaa gccgtaggag cgaccggttg
     7201 ctcgcgccag cgagcgaatg ctcgcacctg cctcgtactg cttcttcaac tgggtctgta
     7261 ggcggtcacg ggacttcccc gtgacgcggg ttcccttacc cagggtggct ttgacttgtg
     7321 cgggcctgtc gctcatggct tcctccgagt cgccgagcag cgtctttcca ggctaagcac
     7381 tcgaggggcc gtgatcaacg ggttcttgtg atgaaactca cgcgagctga atcaattcca
     7441 gataatccgc ggaccagtgg tcctccgtac cgtccggtag caagatcacc cgctccggcg
     7501 agagcgcctc agcggccccc ggatcgtgtg tgacgagcac gaccgcgccg gcgtaagtgc
     7561 gcagcgcatc cagcacttgt tcgcgcgaga ccgggtcgag gttgttggtc ggctcgtcca
     7621 gcagcaacac gttggcagcc gaggacacca gtccggcgag tgccaaccgc gtcttctcac
     7681 caccggacag ggtgcccgcg ggctggtcca actggggacc ggtgaacatg aacgcgccga
     7741 gcagaccgcg caggtcctgc tcccccgcgt ccggcgcggc atgccggatg ttctcccaga
     7801 ccgtcgcgtt gtcgtcgagg gtgtcgtgct cctgcgcgaa atacccgacc ttcatgccgt
     7861 ggcccggcac cagactgccc gcggtgggct gttccacccc ggcgagcagc cgcagcagcg
     7921 tggtcttgcc cgcgccgttg agcccgagca ccaccacccg gctgccgcga tcgatcgcga
     7981 gatccacccc cgcgaagatc tccagcgagc cgtacatctt ggtcaggttc tccgccatca
     8041 gcggcgtttt gccgcagggc gcgggctcgg ggaacttgat cctggccacc ttgtcggcga
     8101 cgcgcacgtc gtcgagttcg gccatcaacc ggtcggcccg cttggccatg ttctgtgccg
     8161 cagtggcttt cgtggccttg gcaccgagct tggcggcctg cacccgcagc gcgctcgcct
     8221 tcttctcggc attggcgcgt tcgcgccggc ggcgctgttc gtcggtggcg cgcgcgtcca
     8281 ggtacttctg ccagcccatg ttgtagacgt cggcctcgcc gcgcaccgcg tcgaggaacc
     8341 acaccttgtt caccacatcg ccgagcagtt ccacgtcgtg gctgatcacg atgaggccac
     8401 cgtcgtggtt ctgcaggaaa ccgcgcagcc aggtgatcga gtcggcgtcg agatggttgg
     8461 tcggctcgtc cagcagcagg atggtgtcgg agcggccgcc gctgccgtcg gacgcggcga
     8521 aaaggatgcg cgccaactcg attcggcgac gctgaccacc cgagagggtg cgcagggcct
     8581 ggccgagcac tcggtccggc aggccgaggc tgtggcagat gcgggccgcg tcgctctcgg
     8641 cgacgtagcc gcccagcgcc gagaagcgat cctcgagcct gccgtacttg cgcaccgcct
     8701 tctcgcgctc gttctcgtcg gccacctcgg ccatcagcgc ctgctgcttc tccatatcgc
     8761 ggatcagcgt gtccagtccg cgcgcggaca gcacgcgatc acgcgcgagg atgtccaggt
     8821 tgccttcccg cggatcctgc ggcagatagc cgatatcgct ggagcgcaag atctttccgg
     8881 catacggttc accctcgccg gccaggatcc gcagcgtggt ggtcttaccc gcaccgttgc
     8941 gcccgaccag tccgatccgg tcgccggact gcacccgcaa tgccggtcca ggggccgaca
     9001 gcagcgtgcg gactccggcc cggacctcca ggtcggtcgc ggtgatcaca ggtttctcct
     9061 ccggatcggt cagtgctggg cggttgctac tcgattgtgc gacgcgttac acacaagaac
     9121 caccgatttt acccgtgatc ggagcagccc ttcacaccac gcgatcggta tgtgacggcc
     9181 gtaactgaac ggcgagtaac ctgcggttgc atgagtgagc gaaacaacgg caccgcgacc
     9241 gatctagtgg gcaagagcgc tttggtcacc ggggccagcc ggggcatcgg caaggcggtg
     9301 gcggcggagc tgctcagccg gggcgcgaac gtgttgatca gcgcccgcaa aaaagatccg
     9361 ctggaagagg ccgccgcgga gctgcgcgcg ctcggccatc agggcgaggt cgtggcgctg
     9421 gccgggaact ccggtcacgc cgaggatcgt gccgcctcga tcgaccggat gatggccgag
     9481 ttcgggtcgg tggacatcct gatcaacaac accggcatca atcccgtgtt cggctcgctg
     9541 atggaggccg atctcgacgc ggtccgcaag atcttcgacg tgaacgtcgt cgccgcgctc
     9601 ggcttcgtgc agctggcata caaggcgtgg atgggcgcgc acggcggtgc ggtggtgaac
     9661 gtggccagcg tcgcgggcct gcgctcctcc ggggtgatcg ccgcgtacgg cgcgtccaag
     9721 gccgcgctca tccggctcac cgacgaactg gcctggcagc tcggcccgaa gatccgggtg
     9781 aacgccgtcg cgcccggcgt gatcaagacg aagttcgccg acgcgctgta ctccgccgac
     9841 gaagaacgcg cggcgagcgt ctatccgctg aaacgcctcg gcacccccga agacgtcgcc
     9901 cgcctgatcg gcttcctggt ctccgacgaa gccgcctgga tcaccggcga aaccgtccgc
     9961 gtagacggcg gcctactctc caccggcggc ctctgattcc gtggatgtcg tggtctgcgg
    10021 gctcgggccg gcaggacgtg cgttggcgca tcgatgtctg gtccgcggtt tgacggtgac
    10081 cgtggtggac cccgcgcccg aacggggctg gcacgccacc tatgcggcgt gggccgacga
    10141 actgccggac tggctcgcgg cggacgcggt ggccgcgaca gtcgcgcagc cgaaggcctg
    10201 gggtacccgc gggcaccgga tcgatcggcc ctacaccgtg ctcgacacgg cacggctacg
    10261 agattcgctg gacgtgacag gggcgcggat catcgccgat cgcgcggtcg aatgcgggcc
    10321 cggcgccgcg gtgctggcct ccggcaccgt gctgcgcggt tgccgggtca tcgatgcccg
    10381 cggtatcggc cgctcccccg ctctggccga gcagacggca tacgggctga tgctcgaccg
    10441 ggaccgctgc cccgacatcg agccgatgtt catggactgg cggccggaca acggcgcgtc
    10501 cgccgacgcg ccgcgctcgt ttctctatgc ggtcccgctc ggcggcgaca cgatgctgct
    10561 cgaggagacc tgcctggtcg gccggcccgc cctcgacggc cgcgagctgc gcgaccggct
    10621 gctgcaccga ttgcgttcgc gcggaatcga agtcaccggc gacgaacggg tcgagcgagt
    10681 ccgcttcccg gtcgaaggcg gcaggccggg gcgtaacacc ttcggcgcgg cgggcggttt
    10741 cgcgcatccg gcgaccggct acagcgtcgc cgccgcactc gccgccgccg acaccgtcgc
    10801 gctcggtgct gcggcatggc cggtttcggc gcgcgcggtg taccgcctgc gcgccgccgg
    10861 attgcgggca ctgctccact tacccacaac cgacctcccg gtttttttcg acgcgttttt
    10921 cacgctgccg ccggccgcgc agcgcgccta cctgtcgggc cgtaccgact tgaatggcac
    10981 cgtcagagcc atgctcggcc tgttcggcac cttgccgcgc ccggtccgtc ggcgcgtcgc
    11041 cgccgcgaca ctcgggacgc ccattcgctc gcgtattcga ataccgtccg ccatcatgga
    11101 ggaatgagtg ggtcttaccg tccagcactc atccgtcccg aaccggtgga gcaccgggtt
    11161 cgcggacgcg gtacccgcgt cgaggggatg cagcagtgag gtcgatctgg aaaggctcga
    11221 tcgcattcgg gctggtgaac gtcccggtca aggtgtacac cgccaccgag gaccacgata
    11281 tccgcttcca ccaggtgcac gccaaggacg gcggccggat caaatacgac cgggtctgca
    11341 ccgtctgcgg taaatccgtg cagtacgccg acatcgacaa ggcctacgaa tcccctgacg
    11401 gcgacaaggt catcctgacc gacgaggatt tcgccaaact gcccgccgcc gagaagcacg
    11461 agatcccggt gttgcagttc gtgccgtccg agcagatcga tccgatcctg tacgagaaga
    11521 gctactacct cgagcccgac tcgagcacgc ccaaggccta cgtgctgctg gccaccacgc
    11581 tggaacggat cgaccgcacg gcgctggtgc atttcacgct gcgccagaag accaggctcg
    11641 ccgcgctgcg cgtgcacgag ggcgtgctgg tgctgcagac cctgctgtgg cccgacgagg
    11701 tccgcgaggt cgaattcgaa tccctcgacg gcgtcgccga accgaagccg caagagatca
    11761 agatggccga gacgctggtc gagaccatgt ccgacgattt cgatccggac cagttcaccg
    11821 acgagtacca gatcgagctg aagcggctgc tggacgaggc gatcgccagc ggcaccggta
    11881 aggtgcccga gcagcccgag tccgcgcccg cggagatgga cgccgaggtg gtcgatctgg
    11941 tcgcggccct gcagcgcagc ctggaagcca gcgggcggcg cagcaccgcc gaggacaacg
    12001 gcaaggatgc gcccgcgaag aagaccgcca agaaagccgc cgcgaagaaa actccggcca
    12061 agaaagccgc gaagaagacc gcagacaagc ccgcgaagaa gaccgccgcc cgcaagggtg
    12121 cgtgagggcc gaggcgcgtc ctgctggcaa actgtcggca tggattctgc cgtagtgatc
    12181 gtcccgatgg gtctcggcca cctgcgccag gtcctcgatc tcggtcacga agtcttcgac
    12241 atcaccacca agccgtacac ctcgtggtcg ctcacctcgg tcgccgagca cctcgacagc
    12301 cccgacaacg cctgctgggt cgccctcgat tccgaccgtg tggtcggttt cgtgctcggg
    12361 tcgatggagt tcgagaaccg cgacgactgg gcctacctgg aatggatcgc cgtcgcaccg
    12421 gacatgcagg ggcacggcat cgcccggcgc ctggtcgacg tctgttccga ggcgttgttc
    12481 gcccgcggcg cgcggcgcat cgtcaccgac gtcgaagacc gcaacgcggc ctccaccgcc
    12541 ctgatgaccc gcagcggctt cacccccgcc gccacggtca ccctgttcgt ccgcccgaat
    12601 cccgatgacc ccgacccgga ttcgcaactc gacgcggccg ccatcgcccc cggcaccaag
    12661 cgcgcgctga tccgccgcgg ccgcctggcc ggcgacaacc accgcgccgc ccgctagcgc
    12721 tcggcctccg ttcggaaact gcccggcctc ccgcacgccg cgccccgccc gtcggcgctc
    12781 gacgatcacg tcggccttcg cgcaccggct gccccgcatg ccagtgcgcg gttcagaccg
    12841 tcgccgcacc ccttctgtct tcccgcaccc gctctgccag gccacagcgg gtgcgagaag
    12901 tcagaagggg tgcggcaggg cagaaagggg gcgactaacc ggccgcctgg gcgcgccctt
    12961 cctcgaagaa cgccaagagg cttgccgccg agtcgaattc ggtgctgggg cgcaacgcac
    13021 cgaagggggc gttccagaaa acacccgtgc gcggtgtcca cgggcctacg tacgcataag
    13081 gtccgggatg ggccgaatca cccggcgaaa caccgtaatt cacctcacct atcgcgctgg
    13141 aaaggtcgaa gtgctcgggc cagagcaccg gcgtgctgtc cggggccaaa catcgtaaag
    13201 ccttgtcccc cagggcgaac cagtcgctga tctgctgcgc ggcgaccgga tcgatgtcca
    13261 tcgcgctgtc cggctccacg ccggtggtgt ccttgtacaa cccgtccggc gcccccggtt
    13321 cgatattcgc gagcttcccg agttcgcgat acgtccccgc cagcgccgcg cgcccctccg
    13381 gccagaccag ttcggcgccg accaccgaca ccggccaccg caccccgccg aacccctgat
    13441 gcaccacccg cagccggatg gtctcgtact gccgatactg cggccccgcg atcaacaatt
    13501 ccgccaccgc atgcaacccg cgccgcgatc gctcgtacat ctgttcgtcc acaccggcat
    13561 cattgccggt gcggacccgg cccgcagcca tttcagctca cggctgagct tcctccgccg
    13621 gcagtgcgat cccgaagtgc gacacgatcg catcgacact gcgcgtcaac ccggacatgc
    13681 tctgcttcag ccccgacacg tcccgcttga gccccgacac atcctgtttg agccccgaca
    13741 cgtcgccctt gaggaaagcc acatcctgct tgagcccagc cacgtcctcc tcgaccgcac
    13801 ccaggcggat ctgcgtgtgc ccagccatga ccttcagggt gctcatactg tgctcgaggc
    13861 gcacgacgcg atcgcgcgta tcgatgatgg cctcctgata ggcgataccg tcgccctccg
    13921 tccgatgcca tttcccttcc agcaccgcca cccgctcttc caacgatgga actttgactg
    13981 acatgtagat ccccctgtcg cgtcgattgg agccctcagc ttaaggccgg acaccggcga
    14041 cgccaccctc ccgatctcgg tccattctgc accctgatcc gggtctattt cggaaccctc
    14101 gaacaggtct cggatggaac cgggagcgac ggatttaccc gaatgtgacc cgaacgtggg
    14161 cccggcgcat cgggtacgga ccatgctggg gagcggtgca tcggagacgg aaggacggcg
    14221 cgtcgtggag ttccacgttc ctatcatcga tatctcgccc tacgtcgagg gcggggacgc
    14281 cgcggcgcgg gccgcggtcg cccgccaggt ggacgaggcg gcgagcacgg tcgggttcat
    14341 gcagatccgc gggcacggga tcgcccggcc ggtgctcgac gagttcgcgg ccgcgctgga
    14401 cgacttcttc gcgctcgcgc ccgccaccaa ggagagctac cgaaccgcgg tcgaattcaa
    14461 tcggggctat tcgccgccca aaagcgagag tctgagtttg agcctcggag tggcgtcggc
    14521 gacccggatg aacgacttct tcgaggcgtt caatatcggc acgaccaccg ccgactatcc
    14581 gggactcgac ctgcctgcgc aggcgggcta cgccgacaat gtctggcccg cagaacttcc
    14641 cgacttccgg ccgcgggtgc agcggtacta cgccgaggcc gcgcgggtcg cgggcacgct
    14701 caccaccgtc ttcgccgacg cgctcgacct accggccggc tatttcgaaa gtttcaccga
    14761 ccactcgctg aatgtgttgc gcatgaacaa ctatgcgctg ccaccgggca gcgtggacct
    14821 cgacggcgac ctcaagggga tgggcgagca caccgattac ggcatcgtca ccgtcctgtg
    14881 ggccgaccag gtacccggct tacaggtgct gggcgcggac ggccgctggc acgacgtgca
    14941 acccgccgac gaggcgctgc tggtgaatct cggtgacgtg atggcccgct ggaccaacga
    15001 gcggtggctc tcgacgctgc accgggtgat gccgccgatc gtcgacggca ccatcgaacg
    15061 ccggcgcagc gccgcgttct tccacgacgg caatttcgac gcggtgatcg agacgctgcc
    15121 ctcctgcgtc ggcgcgggca gcaagtatcc gccgatcacc gtgtccgagc atgtgcaggc
    15181 gaagctggcc ggttctcgtg cgctgcaacc gaatacgaac gcgcaccggg aagcggccag
    15241 ggtgctctcg gcccgtgact gacccggact acttgcggaa cttcgcttcc agttcggtcg
    15301 ccgtggcttg caggtcggcc ggggtgttcg tcttgaagat gccctcgtaa ccggtctcgg
    15361 cccgcaccgc ggcctccacc tccggatcgt ggtacagctc agccagtttc agtagcgtcg
    15421 ggttgtcctt gtcggcggcc cgcgcggcga agatgttgat gtattgcttc agttccgggc
    15481 gctccgggtc gtcggtgtag atggtgtcgt tcttggtcag gcccgcggga cgcgcgaagg
    15541 tgtcgtcgac gaacgcggcg tcgacactgg acagtgactg cgcggtgagg gtcggatcga
    15601 tgggcgtcag cttcaccttg gaagccgcgg tgtccacatc ttcgagcttg gagtcccagc
    15661 tcgcaccgcc tttcagcacg accaggcccg ccgcggcgag gctgagcagc ggccttacct
    15721 ggttggcggg gttgttgctc aacgtgatct ggccgccctg cgggatctcg gcgacggact
    15781 tgtgcttgcg cgagtacagg gtcagcggga agatctcggt cgcgccgacc ggcaccaggg
    15841 tgtcgttgtt gcgggcgttg tagttggcca ggtatcgcac gtgctggaac ttgttgagat
    15901 cgatacgcct ttgcgccagt gcgggattgg gctgattgta atcggtgaag ttgatgaact
    15961 ccacccggat gccttggtcg gccgccttct tcttgtacac gtcccagtgc ggctctgcga
    16021 gatcgttcac accgatacgg atcacgccgt cgtcgtgctt cgcgccacac gacatcgtgg
    16081 tcacggccag ggcggaaagg atcggaatca ccagcagacg gtgcatcaag cgcattgcga
    16141 gcaaactaga cggtcgtcca agaattggga agggtttcgc tcaccacaat cccaaccgtt
    16201 gtcccgcccg cccgtggatc gcttggatta ccgggttcat attgcgacga gcttttcggg
    16261 agcaacgaag tgaaattcca tcgggtactg gcgatcccgg tcctggtagc aaccgcggcc
    16321 ctcaccgtca cggcgtgcgg ttccgacgac aagtccgcct ccgacacggt agtgcgaatc
    16381 ggcaccaccg acaaggacaa ggcctgggac gtcttcgaac agcgggccaa ggacaagggc
    16441 atcacgctga agatcaccaa cttctccgac tacaagcagc cgaatctcgc gttgtcgcaa
    16501 aagcagatcg atgtgaatct ctttcagcac ctgcagttcc tgggcgccta caacgtcgcc
    16561 aacaaggaca cgctgactcc gatcggctcc acctacatcg tgccgctcgg cctgtactcg
    16621 aagaagcaca aggcgctcgc gggcctgccc cagggcgcgg agatcgcgat cccgaacgac
    16681 ccgaccaacc aggcgcgggc gctgttcgtc ctgcaggcgg ccggcctgct gaaactgtcc
    16741 ggcagttcga gcgcgcccac cgccgccgat gtcgacaagg gcgcgtccaa ggtgaaggtg
    16801 accacggtcg acgccgccca gaccgcgctc tcgctcgcat ccgtggacgg cgcggtgatc
    16861 aacaacacct tcctcgaccg ctccggcatc gaccccgatt cggcgctgta caaggatgat
    16921 ccgaagaacc cgtcggccga gccgtacatc aacgcgctgg tgaccagggc cgaggacaag
    16981 aacaacccga agctgctgca gctggtcgaa ctctggcacg accccgaggt gcagcgtgca
    17041 cacgccgagg tcacgaagaa cacggccgtc gaggtgcgcc gcaccggccc cgaactggag
    17101 cagattctcc agcgggtgca gcagaccatc cgtgacggca agtgagcgat aacccgcccg
    17161 ccgtcgaatt ccgctcggtc accaaggttt tcggcaaggg cgcggatgcc catatcgcgc
    17221 tggacgatat cgatctgcgg atcgaacagg gcgagatctt cggcgtgatc gggtattccg
    17281 gcgcgggcaa gagcaccctg gtccgcctga tcaacgcctt ggagcggccg accagcggca
    17341 cgatcgaagt cgcgggcaac cccatcaccg gggtgcgtga ggccgaggtg cgtcgcctgc
    17401 gccgcgatat cgggatggtg ttccagcagt tcaacctgtt ccgatcccgt accgccgcag
    17461 gcaatgtcga atacccgctc aaggtggcgg gctggaagcg ggccgcgcgc aaggcgcggg
    17521 tcgcggagtt gctcgagttc gtcgggctct ccgacaaggc gcgcagctac cccgaccagc
    17581 tgtccggcgg tcagaagcag cgggtcggca tcgcccgcgc gctggcgacc tcaccgtcgc
    17641 tgctgctcgc ggacgaatcg acctcggcgc tggacccgga gaccaccgcg gaggtgctgc
    17701 gcctgctgaa gaaggtcaat cgggaactcg gcgtcaccat cgtggtgatc acccacgaga
    17761 tggatgtcat ccgtgccgtc gccgaccggg tcgccgtgct cgccgagggc cggatcgtcg
    17821 aactcgccag caccttcgag gttttcgcga caccgcaggc cgcgccgacg cagtcgttcg
    17881 tggcgacggt gctgcacaac cggccgtccg aggacgaagt acgcaggctc ggcgagctgc
    17941 acggcggccg gctcgtcacg gtggacgtcg acgacgaaca cggcatcggg gccgcgctga
    18001 ccgtcgcggc gcacgccgat gtccgcttcg aggtggtcta cggcggggtc ggcacgttgc
    18061 agaacaagac gttcggcagc gtcaccctgg cgttgcacgg agccgacgac gccgtcgaca
    18121 aggtgatcgc cgaactcggc ccgcgcacgg cctgaaagga gtaccgatgc aagcggattg
    18181 ggacaaactc cggccgttgc tgaccgaggc gatcggcacc accatctatc tggtgctgat
    18241 caccttcgtg atcggcggcc tgatcggact gttcctgggc accgtgctct acaccacccg
    18301 caagggcggg ctgctcgcga acgccccgat caacctgctg ctcaacgtga tcgtgaacgt
    18361 ggtgcgcccg atcccgttca tcatcctgct cgcggcgctg gggccggtga cgctggaggt
    18421 ggtcggcacc accatcggcc gcgacgccgc ggcgttcgtc atgatcgtgg cggcgtcgtt
    18481 cggcatcgcc cggatcgtgg agcagaatct ggtgacggtc gaccccggcg tgatcgaggc
    18541 ggcgcgcgcg gtcggcgcgg gaccgctgcg aatcatcgtg acgctgttga ttcccgaggc
    18601 gctcggcccg ctgatcctcg gctacacgtt cgtggtgatc tcgatcgtcg acatctccgc
    18661 gatggcgggc accgtcggcg gcggcggact gggcgatttc gcgctggtcc acggatatca
    18721 gcagttcaac tggcaggtca ccttcgtggc cacgctgatc atcgtggcgg gcgtgcaggg
    18781 catccagttc ttcggcaact ggctggcccg aaaagtattg cgccgctgag tcacctggtg
    18841 cccgggacaa ctcccgggca ccaggcgacg gcgtcattcc acgttgctgg tgcagagcgt
    18901 ggtgccgacg atgcgcgccg cgctcggcgc cgagctgccg aaattcaccg gcggcggccc
    18961 gaatgcggcg agcgccgcgc gctcggcttc ggcgcggttg ggaccggtgc caccgacgta
    19021 gcgaccgtcg cgctcggcga tggcgccgca accgtcgacg aagcggacga tgatagtgca
    19081 gttccgcccg cccttcgccc ggcagtcgtc gagcgccgcg gcgtcggatt ccgcccagtt
    19141 cgggtagttc caggccgtcg agacgctggc cccgttcgcg tcgaccgtga tcgcccgcga
    19201 cccgtaatag gagccgtccg gcccgggctc ggcatgggcc tgccccgcgc cggccgccac
    19261 gaaggcgacc gtcgtcgagg cgaacaggcc caggacagcc ttgcccgctg tgtatttcat
    19321 gattctcccc acgaaagaaa acaaacctcg gtcagatcat ccggcatccg aatcgatgag
    19381 tccaagcctt tgcggacggc tgttcacctc gaaataggct gtcatacagg gcctttcgaa
    19441 atgcaaggtt cgattccgcg gggcggaccg ttcagctcgc gttcttggtg cacgaggaca
    19501 gcactacgcg cgcgggttgc ggcacggcac tgccgagatc cgggaatggt ggcgcggtct
    19561 cgccgagctt ggcgatcgcc aatcgctccg cttcctcccg cgtcgccgcc caatcggccg
    19621 cgaacgcacc gtcggcgccg cgcacggccg ccgcacagcc gttggaaaag cgcacgagaa
    19681 tcttgcagtc gtacacgccg cagtcccgaa tcgccaccgc atccgcggtc acccaggacg
    19741 gttgatcgac cgagccgacc actttgccgg tgctgggcga aaaggccagc gtcccatgat
    19801 aatcaggcgc cgcgccggcg gagcccgcgc cgacgatggt caacgccgca gtggatgcca
    19861 ggaccgcacc gaacgcggcc ctccccagat tggacaacag aaactcccgt tcaaagaaga
    19921 tgaagcgagc tgatcatcac ccacaccacc taccctgtcc agcaccagga aatctgccgc
    19981 tgatactcgg ggctgccgcg caatccagcg gcacggcttg ggattcgggt caggccctag
    20041 cgacgcgtgc gcagatactc gtcgtgctcg cgatcctcgc ggtagtaccg ctgcgtgagc
    20101 acggtcagcc tgcggatctc ggcggccatc gcggccgagt ccatcggctt ggcgacgacg
    20161 ggatcaccgg tctgcacgta gtagcggcca tccggatagt ccatccacca gaagccgcgg
    20221 ccgaacgtgg ggcgcgcgtc gacggccggg ccgggcagca ccgtgatctc gccgagcgca
    20281 cggcgctccc gtttgaacag ccggtcgaac cgctgcgcga ggcctaccgc gtacgcttcg
    20341 cgcaccggac gctcccgatc ggcggtgatc tccgcgcgcc gcgcctccaa cggtggatgg
    20401 gtgcccggcg gcgtatccgg cagcgcgcca accgcatcgg cagccacctg ggcggcgggg
    20461 ccgtaccgca gggtcaccgc accgccggtg tccgcggcga cgcccggaag ctgcaccaat
    20521 gtcgcggccg ccgcgtcgcg cactgcaccg tggaaacgga agatccgggt cagctccggc
    20581 gcgccgaacc ccttgagttc gatccggacc tccggttcca gcaggatctg caacgcgcgt
    20641 tccaactcga tcgaatgccg atcgagcagt gcggcagccg ccgcttcccg ctgcgccacc
    20701 agatcggcga aatcgacggc ctgcggccgg aattgcagcg gatacggcag ccggtcccgg
    20761 ccgtaggcgt gccagagcag ctggaactcc agtccggtga aacgcagctc aaccatggtc
    20821 accgatcacc ggtggcaccg tcttcggcag cgcccccaaa ccggtgagtt cctcgccgtt
    20881 ctcctgcgtg atcaggtaat cctttgtacc ggtggtcttt tcgtcgtcgc cgccccggcc
    20941 ggccgcaccc ggcgccatgc cgggcatgcc actcatgccc gcccggccgg tggccgtgcc
    21001 cggcgcggtc cgcgcggcag cggccggaac aacgcccggc tgctgcggat ttccgggcac
    21061 gctgcggccg gggacgggct gcttgccggg ttcgcccgtg gtagtgc
//
