LOCUS       NC_018681              49503 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4301853
            Orig. end                         :: 4351356
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..49503
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="24"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..49503
                     /SMILES="C(C)C(=O)C(C)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..49503
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:29503](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..29503)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    450..465
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: strong, score: 23.87"
                     /tool="antismash"
     misc_feature    complement(690..703)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.03"
                     /tool="antismash"
     gene            complement(764..1855)
                     /gene="pdhA"
                     /locus_tag="O3I_RS19365"
                     /old_locus_tag="O3I_019200"
     CDS             complement(764..1855)
                     /EC_number="1.2.4.1"
                     /GO_component="GO:0045250 - cytosolic pyruvate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /gene="pdhA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928610.1"
                     /locus_tag="O3I_RS19365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019200"
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="WP_014984654.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-08, bitscore:
                     33.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSAPRKTTRRTTKSAPVTAESAFATEDPAILRGLFRDMLFVR
                     RFEERTAQSYQQAKIGGYCHLNLGEEATVVGLGAAMRPTDYLFTNYREHGYALAKGIEP
                     GRVMAELYGRATGTSKGWGGSMHMYDTATRLLGGYAIVGGQVPLAIGAALAIDYRGGDD
                     VVVCQMGEGTTNIGAFHESLNIAALWRLPVVFLVINNQTGMGTTVEHSSAEPDLWKRAA
                     AYRMRGERVDGTDVLAVRDMASELIEAARREGKPALLEAVSYRLKGHSVVDPAKYRSTE
                     AVATAREHDPIALWQHRLLAADVLTDQSLAEIEREVTESVAAAVEFADASPHPDPSSLF
                     DYNYATPVPSDSRRLPADPLFTV"
     gene            complement(1865..3313)
                     /gene="lpdA"
                     /locus_tag="O3I_RS19370"
                     /old_locus_tag="O3I_019205"
     CDS             complement(1865..3313)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928609.1"
                     /locus_tag="O3I_RS19370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019205"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_014984655.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-67, bitscore:
                     226.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEFDLLVIGGGPGGYVAAIRGAQRGLRVGLVEKERPGGVCLNWG
                     CIPTKAMLRSAEVFHTLTAAAEFGVYADNVRFDFAAVRQRKDGVVKELTDGVAGLLKAN
                     GVTVIEGHARFVGPTTVEVHETGASPIFEGGPRYAAAPGAPVRQVSAQDVIVATGSVPA
                     LLPIPGADLPGVVTSDGAFGLTDVPRRLVVIGGSAVGAEWASLFATFGSQVTVVEMQDR
                     LVPLEDKEIGDALGRSFRKRGITVLTGATVTAIAQDDGLRVSVAGPKPQDIPADVVLVG
                     VGRRPNTADLGLDIAGIGTDARGFIEVDDQLRTGVEHVYAIGDVTGRALLAHVASHQGL
                     TAADVIAGHDAHIDYTVIPAATFTHPEIASVGLTEAAARAAGHEVITAKFPFAALGRAK
                     TFGDTEGIMKIVAGQQHREVLGVHIIGPSASDLITEGALAIALEATLDELADTIHAHPT
                     LGEIGMETALAGLGLPVHIAPRKR"
     misc_feature    3320..3340
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            complement(3470..4663)
                     /locus_tag="O3I_RS19375"
                     /old_locus_tag="O3I_019210"
     CDS             complement(3470..4663)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928594.1"
                     /locus_tag="O3I_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019210"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_014984656.1"
                     /transl_table=11
                     /translation="MAAPKHTGPTPGIRRLAAVCRTEVPVLTRRLMAAIFTDIPEWTDY
                     SPVSREDLRNGCRSYLTRVLDLLAGDVTVPDRDDVAAAIGRNRAAQGVPLEVMLRTFRL
                     GGQIVWEALLDHADDLAPGEFREIGAATWSVIDGMSSALVTSYRNTELEQVRRDERRRH
                     GLIEDLLAGRAHDATFAARAARELNLPTHGAYLMVAVRGRPAVQLGTETALAALGIRSV
                     WHDRVDATVGLVSLERHDSSTVLQQIRPRLRGGAAASPPVPGLAQIDTAHALAMLALET
                     LPTDAQGLVLLEERYPEAMLLRSPDLTELLVTRTLGPVLALPEREREILLETLAAWLAE
                     NCSAANAAPLLHCHRNTVINRLQRIATLLGRPLEGQRAYLELSLALAAVELGAAESD"
     gene            complement(4718..4840)
                     /locus_tag="O3I_RS46805"
     CDS             complement(4718..4840)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS46805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_272944300.1"
                     /transl_table=11
                     /translation="MLFALKPDLSTIATVFTGPVAAWLWAETALLHGVPHQSTW"
     gene            complement(4904..5332)
                     /locus_tag="O3I_RS19380"
                     /old_locus_tag="O3I_019215"
     CDS             complement(4904..5332)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (12-120). E-value:
                     3.8e-07. Score: 22.6. Matches aSDomain:
                     nrpspksdomains_O3I_RS19380_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003881530.1"
                     /locus_tag="O3I_RS19380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019215"
                     /product="hypothetical protein"
                     /protein_id="WP_014984657.1"
                     /transl_table=11
                     /translation="MAIVRFHLLSTLAPAQVRHVLTDFGPSRPQAWPSIDAEHFVVHER
                     GDSWAEVTEGTAAAWERARYEWDPAGDTVTVTTLDSKLFGPGGGWVFRLTPDEHGTRVD
                     VELTRTPHAFKAKVLAALLPLVGPASLRKSFARPLQAR"
     aSDomain        complement(4973..5296)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19380_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="3.80E-07"
                     /label="O3I_RS19380_Polyketide_cyc2.1"
                     /locus_tag="O3I_RS19380"
                     /protein_end="120"
                     /protein_start="12"
                     /score="22.6"
                     /tool="antismash"
                     /translation="APAQVRHVLTDFGPSRPQAWPSIDAEHFVVHERGDSWAEVTEGTA
                     AAWERARYEWDPAGDTVTVTTLDSKLFGPGGGWVFRLTPDEHGTRVDVELTRTPHAFKA
                     KVLA"
     gene            5465..8176
                     /locus_tag="O3I_RS19385"
                     /old_locus_tag="O3I_019220"
     CDS             5465..8176
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019049219.1"
                     /locus_tag="O3I_RS19385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019220"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_014984658.1"
                     /transl_table=11
                     /translation="MPMFGRDTELKALRALVDGPGEQSGILVEGEPGIGKSALIEETVA
                     AAAVAGLRVLRTAGAEAELNSAYAGLQRLLYPLRRGFGELPAPQSAALASALGMSDAPG
                     APNGYLVGLAALTLLADAAADRPLLIIAEDVHWLDPASAEVLAFLARRIEAEPLALVVT
                     SRAGGTPLADSGLTPMRLGGLADDDAAALLDSAAPDLAAPVRRRVLAAAQGNPLALSEL
                     ATATVDLTGPMPLTERLERAFSARSVELPPESRSALLVAALNESDSIAETLAAVSILAG
                     SPADPEILTPARTAGLVEMDSGTVTFRHPLQRSAVAAAASAQERRRAHLALADALDAAP
                     DRRIRHRAAGTLGPDEHLAVELEQAAEQARHRAGAVAALERAAALSDTPGGRADRLLRA
                     AEAAVDAGRRDSAERLVAAARALPLTPRHQATANWLLSGFDDGVRESPARVGELAALAS
                     TVAAAGYTDAALRILWGAAMRCFWVEPGPETRRALLAVADALPIPDEDPRMVAINAYVA
                     PFDRGARVIERLRGLAAHTGRDPEVDRFLGSAALQVGAFDLAARFAAAAAPGLRDAGQL
                     GLLPRALTVQSWSLARLGDLAAAAPVAAEAVDLARETGQPFMHGLAIAVQAEIAALRGD
                     HPQAAALVAEAERIGLAAGARPVLATVQLTRGLIALGTGRFDDACADLLRLHDPRDPAH
                     APFLRAYFLTELAEAAVRAGRVEAVHDLIRELAPIAAVTPSPALAIGMRYAQAVFATAA
                     VEERFAAALSADLTGWPGERGRVHLAFGEWLRRQRRIVESRTQLRTARDIFDALGFTAW
                     SERARVELRGAGESSPDRSPAARERLTPHELSIAQLAAQGLTNREIGQRLFLSHRTVST
                     HLHRIFPKLGISARGDLAALLPGLNDTTPDQT"
     misc_feature    6728..6730
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8305..9357
                     /locus_tag="O3I_RS19390"
                     /old_locus_tag="O3I_019225"
     CDS             8305..9357
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (80-209). E-value:
                     1.6e-22. Score: 72.2. Matches aSDomain:
                     nrpspksdomains_O3I_RS19390_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927153.1"
                     /locus_tag="O3I_RS19390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019225"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_014984659.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-17, bitscore: 62.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.7e-11, bitscore:
                     42.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISRRFFGGALAVGATSLAVATLSACATDPAASSATTPASPGAE
                     LRAGSGAHTTLGPIKQIEAGALNIGYAEFGPSTGRPVILLHGWPYDPYSFADVGPLLAA
                     AGYRVLVPFLRGYGPTTFRSPQAVRNGQQSAIARDIVDFMDALRIDQAVLGGFDWGART
                     VDIIAALWPQRCKAIVAVSGYLITQQAAQQQPLAPEAELGWWYQYYFATERGRVGYTRN
                     RHEFNKLIWRRASPQWNFDDATFDRSAAAFDNPDHAEIVIHNYRWRLSLASGEARYDEY
                     EQQLATGPVITVPAITIGSDFDGAAKDGKPYRDKYIGKHEHRVLDGIGHNVPQEAPQPF
                     AQAIIDADRL"
     aSDomain        8545..8931
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19390_Abhydrolase_1.1"
                     /evalue="1.60E-22"
                     /label="O3I_RS19390_Abhydrolase_1.1"
                     /locus_tag="O3I_RS19390"
                     /protein_end="209"
                     /protein_start="80"
                     /score="72.2"
                     /tool="antismash"
                     /translation="PVILLHGWPYDPYSFADVGPLLAAAGYRVLVPFLRGYGPTTFRSP
                     QAVRNGQQSAIARDIVDFMDALRIDQAVLGGFDWGARTVDIIAALWPQRCKAIVAVSGY
                     LITQQAAQQQPLAPEAELGWWYQYY"
     gene            complement(9406..10995)
                     /locus_tag="O3I_RS19395"
                     /old_locus_tag="O3I_019230"
     CDS             complement(9406..10995)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019049231.1"
                     /locus_tag="O3I_RS19395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019230"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_014984660.1"
                     /transl_table=11
                     /translation="MSITSAIALHQLTFEWPDGSVALAGVDGAFTTGRTGLVGRNGAGK
                     STLLRLIAGQLTPTSGRIETTGDVGYLPQTLTLGRDATIAQLLGIADELAALRAIEAGE
                     SDAAHFDTIGDDWDIEARADEALHEIGFGAADLDRTVGAISGGQAVLVAITGLRVQRKP
                     ITLLDEPTNNLDRETRAQLTAFVDAWPGTLVVVSHDLELLEHMDATAELHGATLDVFGG
                     PYSAWRDYVEQQQAAATQAARTAEQALKVEKRQRIEAETKLARRERTGRATQQHGGIPR
                     ILAGNRASKAQASAGAMRTTLDAKVRAAQEVLDAAAARVRSDEHIHLDLPDPDVPRSRR
                     IAELRDGDRGVTIQGPERVAVIGPNGAGKSTLIEDLVHGRRPERGVLLTDRVGYLPQRL
                     DGLDEQASAIENVHAVAVTTPPGTIRNQLARLLLRGAAAERPVSSLSGGERFRVSLARL
                     LLADPPVQLLILDEPTNNLDIASVDQLVEALADYRGALLVVSHDYPFLRRIGIDTVVAL
                     DADGRFQPHASL"
     gene            11246..12751
                     /locus_tag="O3I_RS19400"
                     /old_locus_tag="O3I_019235"
     CDS             11246..12751
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015563.4"
                     /locus_tag="O3I_RS19400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019235"
                     /product="YfcC family protein"
                     /protein_id="WP_014984661.1"
                     /transl_table=11
                     /translation="MDPAVRAGRAQKTWFFPSTYTILAGVALLVWLAAFVIPPGAYDTD
                     ARGRPIAGTYHRVIDAKGFGERLRELFLAPVNGLYGIQDDRSGQVGPDLTGHLYGAAAV
                     FLFVLAVGAFITVAFATGALDSGIGQLAHRLRDRSALLIVGVMLVFAIAGTVEGFAEET
                     LGCYALLVPLLLALGYDRMTAVGTIICGAGVGMLCSTVNPFATGTASSAAGVPLGEGIG
                     LRLAMLVVLTAVTVGYVLRYAERVKRDPAKSWSGWQPGDREGSADDHRPDPLTRRQQAV
                     LWLVAATFAFMIFAIIPWAEVIDGPGAERYRWQLGWYFPELTALFLLGAVVVGLVGGLG
                     ENRVSEAIGKGFGDFVGAGLVIVLARGVTVIMNNTEITSTALHSLEGLVTGTSSTVFAV
                     TVFLVNVPLGFLIPSSSGHATLVMPIMAPLADFANVPRSLVVTAWQSASGWANLVTPTT
                     AVVTGGLALAKVRYDRYVRFVAPLLGILGVLICGFLALGALLR"
     gene            complement(12667..13938)
                     /locus_tag="O3I_RS19405"
                     /old_locus_tag="O3I_019240"
     CDS             complement(12667..13938)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013417607.1"
                     /locus_tag="O3I_RS19405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019240"
                     /product="MFS transporter"
                     /protein_id="WP_014984662.1"
                     /transl_table=11
                     /translation="MHARLGRDFGWLWSAYAVSTYGTWLAFGAFPLLAVRVLDSTAFAV
                     ALLEASGLAVAAVVAFGLGPWVEHRNKQPVMIAMDLVRFGALASVPVAYVLGALTYGQL
                     LVVSVVSGTAGLAFAAASGAYLKHLVRSDELLVAGSRFEGTSWVATAVGPPLGGALIGV
                     FGPVVTITTDAVSFLLSACAVRRIRGGDIATPRAEPPRTGLLTGWRYIRRDRVLVRLFL
                     NSISVSGLIMAGVPLLSVLLLGEYHFPAWQYGLAFGIPALGGFVGARLSGHLARRYGEQ
                     RVMLVSGWLRSVFPLGLAFVQPGIPGLLTVIGVEALLIACMGVFNPLYATARLRRTPRD
                     HAARVLSTWNACAKLLQATLMMLWGVLATCTGPHTAITISGVLLLATPLLLPSAADYRS
                     KAPSARNPQISTPKMPSSGATNRT"
     gene            14059..14988
                     /locus_tag="O3I_RS19410"
                     /old_locus_tag="O3I_019245"
     CDS             14059..14988
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005516781.1"
                     /locus_tag="O3I_RS19410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019245"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_014984663.1"
                     /transl_table=11
                     /translation="MDTEAVRSFVRAAELGQLQQAADELGVTQQAVSKRIAALERALCV
                     RLFTRTARGVELTLDGQAFLPHARTIITSVDRAVAAIEPGSRALRIDVLGLRSAQAVVL
                     HDYWRAHPEIVLDVVTLKVDDPRVAVAAVRAGEIDATFRSVTDPATLPDDVRMIHAFDS
                     RLELLAGPRHPLAAARTLTPAQLRKHRIWVPGIAVRSEWADFYDQLATHFDLRIDAAGP
                     NFGNEVLLDILADSADVATLVGARDRYLWPAHYDLRRIPLANPALVYPLSLIVAAANPH
                     PGLRGVLDHVGSLPPVPADAWRPTWAVR"
     gene            15064..15561
                     /locus_tag="O3I_RS19415"
                     /old_locus_tag="O3I_019250"
     CDS             15064..15561
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019929968.1"
                     /locus_tag="O3I_RS19415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019250"
                     /product="hypothetical protein"
                     /protein_id="WP_014984664.1"
                     /transl_table=11
                     /translation="MTTTQDPQPSDIPDSRDTALYRLEPLVGRWQVEASFAPGFFGPGT
                     PAVKDRSGTTTFEWMKTKQFLVEHSVIDNPMAPDTIVIIGLDRDGLFVRHHYDSRGVSR
                     TYQMSLDGGVLHMWRMEPGFSQRYSGTFSADGNQISGAWEKSADGVEWEHDFDLTYFRI
                     DD"
     gene            15625..16215
                     /locus_tag="O3I_RS19420"
                     /old_locus_tag="O3I_019255"
     CDS             15625..16215
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="O3I_RS19420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019255"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_014984665.1"
                     /transl_table=11
                     /translation="MPDAAPPTITDLDALKVFTHPLRIALYRALNTAGSATASQLAEQV
                     DEAVSLVSYHLRKLAAHGFVVAAPELGTDGRERWWKPVSDKGWSFRSSDFLADPEGAMV
                     VGQVTRQLLADRSERYRAYLDQQSAWPKAWTDAAFSAEYTPRLTSAELAELEAEITAVV
                     RRWQDRGEAAVAAGEADGREHVAVQLYGFPSRP"
     misc_feature    15649..15663
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 20.1"
                     /tool="antismash"
     gene            16212..17450
                     /locus_tag="O3I_RS19425"
                     /old_locus_tag="O3I_019260"
     CDS             16212..17450
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="O3I_RS19425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019260"
                     /product="MFS transporter"
                     /protein_id="WP_014984666.1"
                     /transl_table=11
                     /translation="MSTGAVRAEAAPPAYRDANVLRWLGAFVCSLLGDSVYFLALSWAA
                     IQVGTPAQAGLVLAVAAVPRVLLMLGGGVIADRFGPRKVLIGSDLTRCLVILGAAGVLA
                     VTTPGVWLLALVAMVFGVIDALFLPAVGALPPRITKPDQLARVQGLRGLASRAALIGGS
                     PLGGLALAAGGPSLAFVTAALLFAVSLPLLIAVRIAPLPDDGVAEQHSTAWADLVEGVC
                     YIRRDPVLAPLVVVLAVGELGFTGPLNIGVTLLADERGWGATGLGWIIGGFGVGAAAAS
                     LLLAVGGRVPRAGLVQPVCLVLGAVAIGALAYAPALPAAAGLGIAIGLTAGLSGALCAA
                     LVQTTTVPAYLGRVTAAAGLVTLGLAPLIYPVVGAAIAAWGTRPVFVVSAAIVALGALL
                     GFRATSLRRAELP"
     gene            complement(17579..18358)
                     /locus_tag="O3I_RS42755"
                     /old_locus_tag="O3I_019265"
     CDS             complement(17579..18358)
                     /NRPS_PKS="Domain: Thioesterase (26-240). E-value: 3.7e-25.
                     Score: 81.6. Matches aSDomain:
                     nrpspksdomains_O3I_RS42755_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="O3I_RS42755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019265"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_081594038.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-07, bitscore:
                     31.6, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 1.5e-20, bitscore:
                     73.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 0.00012, bitscore: 20.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQRTVKQPSPWLQHVVSDAQPGTACLVCVPPAGGAAGAYWTWTQ
                     WLPPHIDLLLVQPPGREDRYAEPPEWTLEDVHEQFTHALAALPEVPYHVLGHSMGSLIG
                     THIATWLAPHREVRRLIVSSYRPDPSESRFSRVFPSGRIDQIDLAQLAALSGLDVADWH
                     ALPAEFREGLTRRWYADLALSAELPVPTEPVLDCPITAWLGDHDLMSAGALTAWSKLTT
                     RTCTVETWPGGHDYLFARPTPVRERLLELMETDAPPA"
     aSDomain        complement(17639..18280)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42755_Thioesterase.1"
                     /evalue="3.70E-25"
                     /label="O3I_RS42755_Thioesterase.1"
                     /locus_tag="O3I_RS42755"
                     /protein_end="240"
                     /protein_start="26"
                     /score="81.6"
                     /tool="antismash"
                     /translation="LVCVPPAGGAAGAYWTWTQWLPPHIDLLLVQPPGREDRYAEPPEW
                     TLEDVHEQFTHALAALPEVPYHVLGHSMGSLIGTHIATWLAPHREVRRLIVSSYRPDPS
                     ESRFSRVFPSGRIDQIDLAQLAALSGLDVADWHALPAEFREGLTRRWYADLALSAELPV
                     PTEPVLDCPITAWLGDHDLMSAGALTAWSKLTTRTCTVETWPGGHDYLFAR"
     CDS_motif       complement(18035..18097)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42755_0001"
                     /evalue="5.30E-06"
                     /label="NRPS-te1"
                     /locus_tag="O3I_RS42755"
                     /protein_end="108"
                     /protein_start="87"
                     /score="19.0"
                     /tool="antismash"
                     /translation="PEVPYHVLGHSMGSLIGTHIA"
     gene            complement(18370..19557)
                     /locus_tag="O3I_RS19435"
                     /old_locus_tag="O3I_019270"
     CDS             complement(18370..19557)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.4"
                     /locus_tag="O3I_RS19435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019270"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_014984668.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-15, bitscore:
                     56.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.6e-19, bitscore:
                     66.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.5e-23, bitscore:
                     81.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLYDRPPAPAEALQAVREFARTTLLGHDADFDSGAEPPLALYEP
                     LHKMGLLNWWLPTEYGGAGLGLADSIDLVSELAYADAGSAFTLLISILSSSMVSLYGSP
                     ELKERFLTAMTREGGYSAALGSEQAAGSELINLATTLTRRGDDVVLNGEKMFSTNSGFA
                     DYLVVFARSAGDKKGATYHAVLVPRDTPGVQVVKRWDMIGLRSAGTYQVSFTDCVVPSG
                     HVLNGPGLKIIEVGLNSSRILIGTIALGVARRIRDLCLDYAMTKRLGGRTLIENAVFAG
                     KLGQMEMQIDVMRNQCLAAATEYDAIMATADPAAEFLQRGALRSALTTKMFCGQTGWQV
                     ATVGSEMFGGLGYTTELPIAKYLRDTRAVTIVEAGDDVLRELVFRRFVLPANRRI"
     gene            complement(19561..20004)
                     /locus_tag="O3I_RS19440"
                     /old_locus_tag="O3I_019275"
     CDS             complement(19561..20004)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023123.4"
                     /locus_tag="O3I_RS19440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019275"
                     /product="DUF3291 domain-containing protein"
                     /protein_id="WP_014984669.1"
                     /transl_table=11
                     /translation="MSGEYHLAQANILYAVDSLKSETLADFHELALKIDAMARAAPGFV
                     FRLESLFDLPEDPYMLNISVWEDMATLREFTYRGEHAGSLRIRRKWFKPPRGAPSVLWW
                     LPVGSLPDVGESMARLDLLNAKGPTQEAFTFRRAFPPPVTGKD"
     gene            complement(20001..26420)
                     /locus_tag="O3I_RS42760"
                     /old_locus_tag="O3I_019280"
     CDS             complement(20001..26420)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (29-455). E-value:
                     5.2e-178. Score: 584.2. Matches aSDomain:
                     nrpspksdomains_O3I_RS42760_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (556-853). E-value: 1.3e-103.
                     Score: 338.4. Matches aSDomain:
                     nrpspksdomains_O3I_RS42760_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (922-1083). E-value: 1.2e-58.
                     Score: 190.1. Matches aSDomain:
                     nrpspksdomains_O3I_RS42760_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1392-1570). E-value: 5.1e-58.
                     Score: 188.0. Matches aSDomain:
                     nrpspksdomains_O3I_RS42760_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1682-1752). E-value: 3e-17. Score:
                     54.7. Matches aSDomain: nrpspksdomains_O3I_RS42760_ACP.1"
                     /NRPS_PKS="Domain: TD (1795-2014). E-value: 2.3e-55. Score:
                     179.4. Matches aSDomain: nrpspksdomains_O3I_RS42760_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="O3I_RS42760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019280"
                     /product="type I polyketide synthase"
                     /protein_id="WP_014984670.1"
                     /sec_met_domain="mod_KS (E-value: 3.4e-217, bitscore:
                     720.3, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.7e-87, bitscore:
                     292.1, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.8e-101, bitscore:
                     338.4, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.8e-59, bitscore:
                     198.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-07, bitscore:
                     30.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 8.4e-38, bitscore:
                     128.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTSVDELVEALRESLKENERLKARISEPIAIIGMACRFPGGVRS
                     PEELWELLAADGDAIAPFPTDRGWDTGTLYHPDPEHPGTTYVRAGGFLRDAALFDAGFF
                     GITPREAAAINPQQRLLLECAWESLEHAAIDPTALVGSRTGVFAGVIYQDYSLPLQAPP
                     HDAEGYLLTGELGSVASGRIAYTLGLQGPAVTIDTACSSSLVALHAAAASLRRGECSLA
                     LAGGATVMCHPRVITEMSRQGGLAPDGRSKPFSDNADGAGWGEGVGMLVLERLSDARAN
                     GHEILAVLRGSAINSDGASNGLTAPNGPSQQRVIRDALHACDLSPAEVDAVEAHGTGTA
                     LGDPIEAGALIAAYGAGRPAQRPLWVGSVKSNIGHPQAAAGVAGVIKMVLAMRHETLPA
                     LVHFTTPSRHVDWAEAGVRPLAEAVPWPRGERVRRCGVSSFGISGTNAHVILEEAPVAT
                     AATEPSGPPAEVTPWVVTARSAAALSAQAAALLTAAATERPEDLGFSLALNRSRFDHRA
                     VVVGADRDELLTGLTALSRDESAPQVVRGTAWPDPRPVFVFPGQGGQWPEMAAALVKSS
                     PVFAQSLAECGDALARYVPWSLHDVLDNVAGAPSLDRVDVVQPVLWAVMVALARVWQAY
                     GVEPAAVVGHSQGEIAAACVAGALSLDDGALIVTRRSRAVLPLSGTGAMLSLGLGAAAA
                     RERMARFGTRLSVAAANGPESTVVCGEPDAIAELQAECAAAGVHTRTINADYASHSSHV
                     DPLEPELLDALARVRPRTGSVPMISTVTGAPIEHTALDATYWWQNLRRPVEFETATRQL
                     LTAGHHVFIEISPHPVLAFGIEGTVEATRAEAAVVATLRRDDGGLDRMTTALAQAHAYG
                     VPVDWDAYFAPTRPRRIPLPTYAFQRQRYWLTDAPRTGPADLTAAGLERPAHPLIGAGV
                     QLADTEGHLFTASLSLERQPWLADHTVGGEVILPGTAMVELALRAGEQVGAEWVDELVL
                     EAPLVLPGDDTVQVQLTVGAVDDTGGRRVSLYSRRGGLGAWTRHAHGTVSPTWEPPADG
                     FAEWPPTGAAPMDVDAVYDRAAQAGMTYGPAFRGLNRLWRSGAEYYLESRLPDEIAMDA
                     GQYGLHPALTDAVLHGCLAALADRNALTHAAVLPFTWTGVGLYTLGAAAVRARITPLGD
                     TEFRVDLADDAGEAVGQIATLSFRPAGSLLQGATQALSTVRWTSLAAPADTGPGDELWV
                     LGDDLARQLADAGIEFGRCADATAVNSSGPVLLDVAPVATPAGVARAALDRVRQVLSDI
                     RAWLAATGDPAARLAVITHRAVAITPDEDVTDLASAAVWGLIRTAQAEYPGRFVLVDLD
                     DEPASARALPSALRTAEEQLAIRDGHLSTPRIGPLRTEATAPPLAEPDHTVLITGGTGG
                     LGGLLARHLATAHHVRHLLLVSRRGETSPGAAELVAELTALGAEVRVAACDIADYAATA
                     ELLRSLPADRPLGAVIHAAGVLDDGTVETLTDAQIERVMRAKVDGAVNLHLLTEGLELS
                     GFLTYSSVAGVLGTPGQANYAAGNAFLDALVQHRRAHGLPGISLAWGPWASDAGMTEGL
                     SEVDHARLGRWGLLPLDAADGCALFDAARAADRPLAIPCRIQLTRAGDAQLVPAMLRDM
                     VRAAPRPRQATSAPRADDTAREREQLRDHLIGLPAVQRREELVRMITRHAAEVANLASA
                     DEVAADLPLMALGFDSLASLELRNRLVHQLGLTGHLSANAVFQTPTPAGLAARIATILT
                     GDDESTAVEEPVPDQVGLPDDIVPAATSGPVALAAAAHLFVTGATGFVGSFLVRELLDR
                     TSSTVHCLVESPNAAQGLAQLRDTMRGYRLWDDAIADRLIVVPGRLTDPHFGLTEREFD
                     ALARTVDGVFHCAAVVDESESVDGMAAVLRLAARHRTVPVHHLSTFAVFGPPDTAGPAP
                     AEDAPTGPSAALTDEYAQAGWIAEEMAARARERGLPISIYRLPPTDLLWRVVQGCIQAG
                     VAPATELTGDIIPVGYAAKAIAALSCDGKAAGATFHLSSPEPVPFASIIATLAARGYPL
                     AELPAGLWADMIAGDPDNAAHPVLQAFSEIAFEQPDHGRSSFESTATRAALTSVGVSGP
                     PASAASLAATIDYFIETGHLPAAQEASTR"
     aSDomain        complement(20379..21035)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_TD.1"
                     /evalue="2.30E-55"
                     /label="O3I_RS42760_TD.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="2014"
                     /protein_start="1795"
                     /score="179.4"
                     /tool="antismash"
                     /translation="FVTGATGFVGSFLVRELLDRTSSTVHCLVESPNAAQGLAQLRDTM
                     RGYRLWDDAIADRLIVVPGRLTDPHFGLTEREFDALARTVDGVFHCAAVVDESESVDGM
                     AAVLRLAARHRTVPVHHLSTFAVFGPPDTAGPAPAEDAPTGPSAALTDEYAQAGWIAEE
                     MAARARERGLPISIYRLPPTDLLWRVVQGCIQAGVAPATELTGDIIPVGYAAKAIA"
     aSModule        complement(20379..26333)
                     /complete
                     /domains="nrpspksdomains_O3I_RS42760_PKS_KS.1"
                     /domains="nrpspksdomains_O3I_RS42760_PKS_AT.1"
                     /domains="nrpspksdomains_O3I_RS42760_PKS_DH.1"
                     /domains="nrpspksdomains_O3I_RS42760_PKS_KR.1"
                     /domains="nrpspksdomains_O3I_RS42760_ACP.1"
                     /domains="nrpspksdomains_O3I_RS42760_TD.1"
                     /final_module
                     /locus_tags="O3I_RS42760"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       complement(20976..21032)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0013"
                     /evalue="1.70E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1815"
                     /protein_start="1796"
                     /score="1.4"
                     /tool="antismash"
                     /translation="VTGATGFVGSFLVRELLDR"
     aSDomain        complement(21165..21374)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_ACP.1"
                     /evalue="3.00E-17"
                     /label="O3I_RS42760_ACP.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1752"
                     /protein_start="1682"
                     /score="54.7"
                     /tool="antismash"
                     /translation="MITRHAAEVANLASADEVAADLPLMALGFDSLASLELRNRLVHQL
                     GLTGHLSANAVFQTPTPAGLAARIA"
     aSDomain        complement(21711..22244)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_PKS_KR.1"
                     /evalue="5.10E-58"
                     /label="O3I_RS42760_PKS_KR.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1570"
                     /protein_start="1392"
                     /score="188.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="TVLITGGTGGLGGLLARHLATAHHVRHLLLVSRRGETSPGAAELV
                     AELTALGAEVRVAACDIADYAATAELLRSLPADRPLGAVIHAAGVLDDGTVETLTDAQI
                     ERVMRAKVDGAVNLHLLTEGLELSGFLTYSSVAGVLGTPGQANYAAGNAFLDALVQHRR
                     AHGLPGISLAWGPWA"
     CDS_motif       complement(21756..21857)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0012"
                     /evalue="9.70E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1555"
                     /protein_start="1521"
                     /score="63.2"
                     /tool="antismash"
                     /translation="FLTYSSVAGVLGTPGQANYAAGNAFLDALVQHRR"
     CDS_motif       complement(22143..22244)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0011"
                     /evalue="6.50E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1426"
                     /protein_start="1392"
                     /score="28.4"
                     /tool="antismash"
                     /translation="TVLITGGTGGLGGLLARHLATAHHVRHLLLVSRR"
     aSDomain        complement(23172..23654)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_PKS_DH.1"
                     /evalue="1.20E-58"
                     /label="O3I_RS42760_PKS_DH.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="1083"
                     /protein_start="922"
                     /score="190.1"
                     /tool="antismash"
                     /translation="HPLIGAGVQLADTEGHLFTASLSLERQPWLADHTVGGEVILPGTA
                     MVELALRAGEQVGAEWVDELVLEAPLVLPGDDTVQVQLTVGAVDDTGGRRVSLYSRRGG
                     LGAWTRHAHGTVSPTWEPPADGFAEWPPTGAAPMDVDAVYDRAAQAGMTYGPAFRGL"
     CDS_motif       complement(23496..23570)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0010"
                     /evalue="5.40E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="O3I_RS42760"
                     /protein_end="975"
                     /protein_start="950"
                     /score="34.9"
                     /tool="antismash"
                     /translation="WLADHTVGGEVILPGTAMVELALRA"
     aSDomain        complement(23862..24752)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_PKS_AT.1"
                     /evalue="1.30E-103"
                     /label="O3I_RS42760_PKS_AT.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="853"
                     /protein_start="556"
                     /score="338.4"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGGQWPEMAAALVKSSPVFAQSLAECGDALARYVPWSLHDV
                     LDNVAGAPSLDRVDVVQPVLWAVMVALARVWQAYGVEPAAVVGHSQGEIAAACVAGALS
                     LDDGALIVTRRSRAVLPLSGTGAMLSLGLGAAAARERMARFGTRLSVAAANGPESTVVC
                     GEPDAIAELQAECAAAGVHTRTINADYASHSSHVDPLEPELLDALARVRPRTGSVPMIS
                     TVTGAPIEHTALDATYWWQNLRRPVEFETATRQLLTAGHHVFIEISPHPVLAFGIEGTV
                     EATRAEAAVVATLRRD"
     CDS_motif       complement(23934..23963)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0009"
                     /evalue="7.60E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="O3I_RS42760"
                     /protein_end="829"
                     /protein_start="819"
                     /score="9.1"
                     /tool="antismash"
                     /translation="FIEISPHPVL"
     CDS_motif       complement(24006..24053)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0008"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="O3I_RS42760"
                     /protein_end="805"
                     /protein_start="789"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LDATYWWQNLRRPVEF"
     CDS_motif       complement(24159..24188)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0007"
                     /evalue="1.40E-02"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="O3I_RS42760"
                     /protein_end="754"
                     /protein_start="744"
                     /score="8.6"
                     /tool="antismash"
                     /translation="DYASHSSHVD"
     CDS_motif       complement(24405..24515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0006"
                     /evalue="1.90E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="O3I_RS42760"
                     /protein_end="672"
                     /protein_start="635"
                     /score="58.3"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAACVAGALSLDDGALIVTRRS"
     CDS_motif       complement(24519..24590)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0005"
                     /evalue="1.30E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="O3I_RS42760"
                     /protein_end="634"
                     /protein_start="610"
                     /score="30.2"
                     /tool="antismash"
                     /translation="LDRVDVVQPVLWAVMVALARVWQA"
     CDS_motif       complement(24705..24758)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0004"
                     /evalue="1.20E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="572"
                     /protein_start="554"
                     /score="23.7"
                     /tool="antismash"
                     /translation="VFVFPGQGGQWPEMAAAL"
     aSDomain        complement(25056..26333)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS42760_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.20E-178"
                     /label="O3I_RS42760_PKS_KS.1"
                     /locus_tag="O3I_RS42760"
                     /protein_end="455"
                     /protein_start="29"
                     /score="584.2"
                     /tool="antismash"
                     /translation="IAIIGMACRFPGGVRSPEELWELLAADGDAIAPFPTDRGWDTGTL
                     YHPDPEHPGTTYVRAGGFLRDAALFDAGFFGITPREAAAINPQQRLLLECAWESLEHAA
                     IDPTALVGSRTGVFAGVIYQDYSLPLQAPPHDAEGYLLTGELGSVASGRIAYTLGLQGP
                     AVTIDTACSSSLVALHAAAASLRRGECSLALAGGATVMCHPRVITEMSRQGGLAPDGRS
                     KPFSDNADGAGWGEGVGMLVLERLSDARANGHEILAVLRGSAINSDGASNGLTAPNGPS
                     QQRVIRDALHACDLSPAEVDAVEAHGTGTALGDPIEAGALIAAYGAGRPAQRPLWVGSV
                     KSNIGHPQAAAGVAGVIKMVLAMRHETLPALVHFTTPSRHVDWAEAGVRPLAEAVPWPR
                     GERVRRCGVSSFGISGTNAHVILEEAP"
     CDS_motif       complement(25278..25322)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0003"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="O3I_RS42760"
                     /protein_end="381"
                     /protein_start="366"
                     /score="10.1"
                     /tool="antismash"
                     /translation="GSVKSNIGHPQAAAG"
     CDS_motif       complement(25383..25427)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0002"
                     /evalue="6.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="O3I_RS42760"
                     /protein_end="346"
                     /protein_start="331"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     CDS_motif       complement(25803..25850)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS42760_0001"
                     /evalue="1.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="O3I_RS42760"
                     /protein_end="206"
                     /protein_start="190"
                     /score="20.4"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLVA"
     gene            complement(26417..29503)
                     /locus_tag="O3I_RS19450"
                     /old_locus_tag="O3I_019285"
     CDS             complement(26417..29503)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (13-437). E-value:
                     6.2e-163. Score: 534.6. Matches aSDomain:
                     nrpspksdomains_O3I_RS19450_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (538-835). E-value: 4.2e-105.
                     Score: 343.3. Matches aSDomain:
                     nrpspksdomains_O3I_RS19450_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (915-984). E-value: 1.1e-27. Score:
                     88.2. Matches aSDomain: nrpspksdomains_O3I_RS19450_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="O3I_RS19450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019285"
                     /product="type I polyketide synthase"
                     /protein_id="WP_014984671.1"
                     /sec_met_domain="mod_KS (E-value: 2.1e-188, bitscore:
                     625.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.1e-78, bitscore:
                     260.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6e-103, bitscore: 343.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-11, bitscore:
                     42.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFTTHKRAAEPIAIIGMACRYPGNSVSPQAFWDLLSAGATAVT
                     DFPADRGWDLDRLRADPARAGASAVHRGGFLDAAAFDAAFFGISPREAAAMHPEQRLLL
                     EVAWEACEHAMVDPHSLRATNTGVYAAQLSTAYGPPLHLAPDGAAGLMLTGNIAAAISG
                     RIAYTLGVTGPAITIDTASSGSLVAIHLAVQALRAGECDRALAGGVSVMPTPGFFTEFT
                     RQQGLAPDGRAKPFAADADGTVWSEGAGMIMLARLSDAQATGHRVLAVIRGSAVNSDGA
                     SAGLTAPSATAQQQLITRTLADAGLSAADVDAVEAHGSGTRAGDRAEATALVATYGVDR
                     ARDRPLRVGSVKSNIGHAQAAAGVAGLIKSVLALQHEKLPGLVHFGTPSPEVDWAAAAV
                     LPLTETEPWPRGERPRRCGVSSFGVAGTNAHVIVEEAPEFETADPAAPAPADVLPWVIS
                     ARSETGLRAQAARLRTAADTERPADIGYSLAVTRSRFDHRAVIVGTDRAELMSGLEAVS
                     RGVPAAQVVRGTAWPDPRPVFVFPGQGGQWPGMATALAKSSPEFAGHLADCAAALRPYL
                     PWSLPDVLDGVAGAPSLERVDVVQPVLWAVMVALARVWQGYGVEPAAVVGHSQGEIAAA
                     CVAGALSLDDGARVVARRSQVVLPLSGTGAMLSLGLGADAARKRMARYGTRLDIAAING
                     PGSVAVCGEPAAIAQLQAECEADDIRARPINADYASHSSHVDPVERELREALASVRPRT
                     GAAPMYSTVTGAPIRHETLDAEYWWRNLRRPVQFEAATRSLLAAGHHVFIEISPHPVLA
                     FGLEGTIEATGADAAVLATLRRDDGGLDRMTMSLAQADAHGVAVDWHTYFAPARPRRIP
                     LPTYAFQRRRYWLDAPGAPATAAVPVAVTGPEPAAPSATPRDIRDLVVREIAAVLGLGT
                     AAEVSVDQSFKALGFESMTSVELRNRLSVALGRRLPTTLIYDYPSPRALADHLAGLGDD
                     PSDNPDRDDAQAPTARGPRGFDDMDGAELVRLALGKEAR"
     aSDomain        complement(26552..26758)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19450_ACP.1"
                     /evalue="1.10E-27"
                     /label="O3I_RS19450_ACP.1"
                     /locus_tag="O3I_RS19450"
                     /protein_end="984"
                     /protein_start="915"
                     /score="88.2"
                     /tool="antismash"
                     /translation="DLVVREIAAVLGLGTAAEVSVDQSFKALGFESMTSVELRNRLSVA
                     LGRRLPTTLIYDYPSPRALADHLA"
     aSModule        complement(26552..29464)
                     /complete
                     /domains="nrpspksdomains_O3I_RS19450_PKS_KS.1"
                     /domains="nrpspksdomains_O3I_RS19450_PKS_AT.1"
                     /domains="nrpspksdomains_O3I_RS19450_ACP.1"
                     /locus_tags="O3I_RS19450"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(26999..27889)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19450_PKS_AT.1"
                     /evalue="4.20E-105"
                     /label="O3I_RS19450_PKS_AT.1"
                     /locus_tag="O3I_RS19450"
                     /protein_end="835"
                     /protein_start="538"
                     /score="343.3"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGGQWPGMATALAKSSPEFAGHLADCAAALRPYLPWSLPDV
                     LDGVAGAPSLERVDVVQPVLWAVMVALARVWQGYGVEPAAVVGHSQGEIAAACVAGALS
                     LDDGARVVARRSQVVLPLSGTGAMLSLGLGADAARKRMARYGTRLDIAAINGPGSVAVC
                     GEPAAIAQLQAECEADDIRARPINADYASHSSHVDPVERELREALASVRPRTGAAPMYS
                     TVTGAPIRHETLDAEYWWRNLRRPVQFEAATRSLLAAGHHVFIEISPHPVLAFGLEGTI
                     EATGADAAVLATLRRD"
     CDS_motif       complement(27071..27100)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0009"
                     /evalue="3.10E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="O3I_RS19450"
                     /protein_end="811"
                     /protein_start="801"
                     /score="10.2"
                     /tool="antismash"
                     /translation="FIEISPHPVL"
     CDS_motif       complement(27143..27190)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0008"
                     /evalue="2.80E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="O3I_RS19450"
                     /protein_end="787"
                     /protein_start="771"
                     /score="16.2"
                     /tool="antismash"
                     /translation="LDAEYWWRNLRRPVQF"
     CDS_motif       complement(27296..27325)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0007"
                     /evalue="6.10E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="O3I_RS19450"
                     /protein_end="736"
                     /protein_start="726"
                     /score="9.6"
                     /tool="antismash"
                     /translation="DYASHSSHVD"
     misc_feature    complement(27374..27376)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(27542..27652)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0006"
                     /evalue="5.70E-20"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="O3I_RS19450"
                     /protein_end="654"
                     /protein_start="617"
                     /score="63.0"
                     /tool="antismash"
                     /translation="GVEPAAVVGHSQGEIAAACVAGALSLDDGARVVARRS"
     CDS_motif       complement(27659..27727)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0005"
                     /evalue="5.00E-10"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="O3I_RS19450"
                     /protein_end="615"
                     /protein_start="592"
                     /score="31.5"
                     /tool="antismash"
                     /translation="LERVDVVQPVLWAVMVALARVWQ"
     CDS_motif       complement(27842..27895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0004"
                     /evalue="1.80E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="O3I_RS19450"
                     /protein_end="554"
                     /protein_start="536"
                     /score="26.2"
                     /tool="antismash"
                     /translation="VFVFPGQGGQWPGMATAL"
     aSDomain        complement(28193..29464)
                     /ASF="found active site cysteine: False, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19450_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="6.20E-163"
                     /label="O3I_RS19450_PKS_KS.1"
                     /locus_tag="O3I_RS19450"
                     /protein_end="437"
                     /protein_start="13"
                     /score="534.6"
                     /tool="antismash"
                     /translation="IAIIGMACRYPGNSVSPQAFWDLLSAGATAVTDFPADRGWDLDRL
                     RADPARAGASAVHRGGFLDAAAFDAAFFGISPREAAAMHPEQRLLLEVAWEACEHAMVD
                     PHSLRATNTGVYAAQLSTAYGPPLHLAPDGAAGLMLTGNIAAAISGRIAYTLGVTGPAI
                     TIDTASSGSLVAIHLAVQALRAGECDRALAGGVSVMPTPGFFTEFTRQQGLAPDGRAKP
                     FAADADGTVWSEGAGMIMLARLSDAQATGHRVLAVIRGSAVNSDGASAGLTAPSATAQQ
                     QLITRTLADAGLSAADVDAVEAHGSGTRAGDRAEATALVATYGVDRARDRPLRVGSVKS
                     NIGHAQAAAGVAGLIKSVLALQHEKLPGLVHFGTPSPEVDWAAAAVLPLTETEPWPRGE
                     RPRRCGVSSFGVAGTNAHVIVEEAP"
     CDS_motif       complement(28415..28459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0003"
                     /evalue="6.00E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="O3I_RS19450"
                     /protein_end="363"
                     /protein_start="348"
                     /score="12.2"
                     /tool="antismash"
                     /translation="GSVKSNIGHAQAAAG"
     CDS_motif       complement(28520..28564)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0002"
                     /evalue="9.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="O3I_RS19450"
                     /protein_end="328"
                     /protein_start="313"
                     /score="8.9"
                     /tool="antismash"
                     /translation="VEAHGSGTRAGDRAE"
     CDS_motif       complement(28940..28987)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19450_0001"
                     /evalue="3.60E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="O3I_RS19450"
                     /protein_end="188"
                     /protein_start="172"
                     /score="13.1"
                     /tool="antismash"
                     /translation="GPAITIDTASSGSLVA"
     gene            complement(29577..30533)
                     /locus_tag="O3I_RS19455"
                     /old_locus_tag="O3I_019290"
     CDS             complement(29577..30533)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003886408.1"
                     /locus_tag="O3I_RS19455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019290"
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_014984672.1"
                     /sec_met_domain="ADH_N (E-value: 1.3e-23, bitscore: 81.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.1e-19, bitscore:
                     68.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNEPPPAAAAGETLVRVTAVGICGSDLHWYEDGAIGDAKLGEPL
                     IPGHEGAGEIVTGPRRGERVAIDPAIPCEACRACRDGYRNLCYHVRFAGHGVTDGMLRE
                     ILPWPTHRLHPLPDNVSDAAGALLEPLAVALWALDLGPVPFGGTAAVVGCGPVGLLLIQ
                     VLRAAGVSRVLAVEPLAHRRDAAAKWGADEILDPYPAADPPDFAAHGVDVAFEMAGNDD
                     AVHIAMAATRPGGRVVLGGIPGSDTTTFRASLARGKELTIAMVRRSNETHPRAIDLAAR
                     GVVELDPLVSSRVPLTEAPAAFADAQRRTGLKVIITP"
     misc_feature    complement(30195..30197)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    30571..30585
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.63"
                     /tool="antismash"
     gene            30886..32016
                     /locus_tag="O3I_RS19460"
                     /old_locus_tag="O3I_019295"
     CDS             30886..32016
                     /NRPS_PKS="Domain: Abhydrolase_1 (91-200). E-value:
                     1.4e-18. Score: 59.3. Matches aSDomain:
                     nrpspksdomains_O3I_RS19460_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015356215.1"
                     /locus_tag="O3I_RS19460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019295"
                     /product="epoxide hydrolase family protein"
                     /protein_id="WP_202804986.1"
                     /sec_met_domain="PF00561 (E-value: 1e-14, bitscore: 53.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPFEVEIPESVVTDARERLRRTRWPEPETVGDWSQGTPAAYLRG
                     LCRYWLEDYDWRAAQRRLNRFPQFRTEIDGLPVHFVHARSPHPGAIALLITHGWPGSVT
                     EFQKVVAPLTDPVSFGGNASDAFHVVCPSLPGFGFSGKPERTGWGAERIADAWDQLMRR
                     LGYARYAAQGGDWGARITMALARRHPQQVIGIHLNMVPFRAPVGAEDLTEADRRAVAAL
                     AGHRAQGSAYAAIQATRPQSIGYGLTDSPAALAGWIIDKFEAWSDCGGDPGTVFTEDEL
                     LDNLLMYWLPATGASAARLYWESFATATGDDSRITVPTGCSVFPADIYRPTRRLAEPQF
                     ADLRHWNELDRGGHFAALEQPAVFVDEVRATFRGLR"
     aSDomain        31159..31485
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19460_Abhydrolase_1.1"
                     /evalue="1.40E-18"
                     /label="O3I_RS19460_Abhydrolase_1.1"
                     /locus_tag="O3I_RS19460"
                     /protein_end="200"
                     /protein_start="91"
                     /score="59.3"
                     /tool="antismash"
                     /translation="ALLITHGWPGSVTEFQKVVAPLTDPVSFGGNASDAFHVVCPSLPG
                     FGFSGKPERTGWGAERIADAWDQLMRRLGYARYAAQGGDWGARITMALARRHPQQVIGI
                     HLNMV"
     gene            complement(32027..33424)
                     /locus_tag="O3I_RS19465"
                     /old_locus_tag="O3I_019300"
     CDS             complement(32027..33424)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="O3I_RS19465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019300"
                     /product="MFS transporter"
                     /protein_id="WP_014984674.1"
                     /transl_table=11
                     /translation="MTAHIPDNPAVLPVDSRRWRILAVASAAQFLAILDLFAVNVAFPA
                     LEQTFHGSTLAQVSWVLNAYTIVLAAMLVPAGRMADDIGRKAAFLVGMTLFGVASLGCA
                     LAPTLGVLVAARVVQAVAGAILIPTSLGLALPAFPPREHAKVMGIWTAVAAAGAGSGPV
                     AGGLLLAAGWRWIFLINIPVVVVAVLAGRRVLPAAARGTRKRLDLLGATLVLCTAAGLT
                     TVFVQAPEWGYGSKAILGCALATVLLAALTVRHLRRAPDPVVSFELFRHRLFTVAVGGL
                     FLYYLAFAAMILAATLFLTGRWHYSVVTAALSIAPMPLSTMTTALLYGRIVARVGARIA
                     TMLGGLALAAGCGWWALTATDRPQYLVVFLPGAVLAGISTALLQPALFGSAATLPSEQT
                     SLASAVLMMSRQLSSALGVAILTVLLGHQALRDFRIAWLAMAAAALAAAIAGLRFRDNS
                     AGREPVR"
     misc_feature    complement(32135..32137)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            33497..34495
                     /locus_tag="O3I_RS19470"
                     /old_locus_tag="O3I_019305"
     CDS             33497..34495
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009073834.1"
                     /locus_tag="O3I_RS19470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019305"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_014984675.1"
                     /transl_table=11
                     /translation="MPSVPGTLAVLLLSQQAAIEVALACQAFGTPPHDHVGDWYDLRLC
                     GVDGAGAHVGLRAWFGHAGPAGSFGMCATHGLDDLATADTVLVPGTGDVRTDPPAAALA
                     AIRAARARGARMVSLCSGAFVLAAAGVLDGRTATSHWEHAALLASRFPAVRVDPNILYT
                     DEPDVLTSAGLMAGIDLCLHVIRADLGSRAANAVARRMIVPPHRAGGQAQYLESPVPAP
                     RGGSGLGEVLEWAMARLDQPTGVGDLAAEAGVSVRTLIRRFHAELGTTPSRWLLVQRLA
                     RARELLEHTGLPVDLVAAHSGLGTAPNLRAHFARELGLSPTKYRRDYHPGQ"
     gene            complement(34521..35861)
                     /locus_tag="O3I_RS19475"
                     /old_locus_tag="O3I_019310"
     CDS             complement(34521..35861)
                     /EC_number="5.4.3.8"
                     /NRPS_PKS="Domain: Aminotran_3 (38-374). E-value: 1.1e-63.
                     Score: 207.3. Matches aSDomain:
                     nrpspksdomains_O3I_RS19475_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011211694.1"
                     /locus_tag="O3I_RS19475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019310"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_041562716.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.5e-70, bitscore:
                     236.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASTSNEIQFDRARQVIPGGVNSPVRAFRSVGGAPRFIVSAAGP
                     YVTDVTGREYVDLVASWGPAILGHAHPEVVAAVQDAAARGLSFGASTPAETELAELVVA
                     RLGGPRAGGGLIDELRLVSTGTEATMTAIRLARGFTGKPLVVKFAGHYHGHSDGLLAAA
                     GSGVATFGLPASAGVPEPIAAQTIVLPYNDIAAVHAAFAAHPGQIAAVIVEAAAANMGV
                     VAPGDGFNAALAAVVHEHDALLILDEVLTGFRVAPDGYWGLERSRSTAPYDADLVAFGK
                     VIGGGMPLAAVGGRHDVMACLAPDGPVYQAGTLSGNPLAVAAGLATLRLADQKTYDLLD
                     ETSSTIQTATTAALTEAGVAHTIQSAGNLFSVLFSPTPARDYAAVQAQDTFRFPPFFHT
                     MLEHGVALPPSVYEAWFVTAAHDDRALTTILDALPHAARAAAAARPE"
     aSDomain        complement(34740..35747)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19475_Aminotran_3.1"
                     /evalue="1.10E-63"
                     /label="O3I_RS19475_Aminotran_3.1"
                     /locus_tag="O3I_RS19475"
                     /protein_end="374"
                     /protein_start="38"
                     /score="207.3"
                     /tool="antismash"
                     /translation="IVSAAGPYVTDVTGREYVDLVASWGPAILGHAHPEVVAAVQDAAA
                     RGLSFGASTPAETELAELVVARLGGPRAGGGLIDELRLVSTGTEATMTAIRLARGFTGK
                     PLVVKFAGHYHGHSDGLLAAAGSGVATFGLPASAGVPEPIAAQTIVLPYNDIAAVHAAF
                     AAHPGQIAAVIVEAAAANMGVVAPGDGFNAALAAVVHEHDALLILDEVLTGFRVAPDGY
                     WGLERSRSTAPYDADLVAFGKVIGGGMPLAAVGGRHDVMACLAPDGPVYQAGTLSGNPL
                     AVAAGLATLRLADQKTYDLLDETSSTIQTATTAALTEAGVAHTIQSAGNLFSVLF"
     misc_feature    complement(35827..35842)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.81"
                     /tool="antismash"
     gene            complement(35867..37354)
                     /locus_tag="O3I_RS19480"
                     /old_locus_tag="O3I_019315"
     CDS             complement(35867..37354)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="O3I_RS19480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019315"
                     /product="cytochrome P450"
                     /protein_id="WP_014984677.1"
                     /sec_met_domain="p450 (E-value: 7.9e-88, bitscore: 294.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEAPPLIDTAAEPARAPGPTGLDAFRVMTRIRRDPCSAFQELVE
                     RYGNIVRIDASGQQFFLVNDPDLVEAVFVARQSNYGKTLNAKVAAMALGNGLLTNEGES
                     WTRQRRIMQPLFARRQLDRFAESMIDAAERALARWATRPDGDRLDVSVAMNALTLDVTG
                     PALFGGDLSDDAARVHEALVEILRCVGKAMTSLLTWLPLRIPGITPDSALRLQAPRWRK
                     LDAAVGVLDDVVARLIRERQDDRRDERHDLLGLLLDARDEAGAAAMSPRQVRDELKTFL
                     LVGHDTTAYSLAWTLLLLSNHPEARERLIAEVDTVLGGRRPTPADLDQLPWTSAVIEEA
                     MRLYPPSWLIERQAIADDVLGGYHVPAGATVYVAPYLLHHDPRSWPNPEGFDPRRFLPE
                     HRQFVFPAADATANPLVRPRFSYLPFGAGHRQCIGLGFARIQAKLILAMLTQRYTFDLA
                     AGARVLPEHTLTLRPRDGLPMVLRRRAAAADSAAPLG"
     gene            37587..38897
                     /locus_tag="O3I_RS19485"
                     /old_locus_tag="O3I_019320"
     CDS             37587..38897
                     /EC_number="6.3.1.-"
                     /GO_function="GO:0004356 - glutamine synthetase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012348.4"
                     /locus_tag="O3I_RS19485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019320"
                     /product="glutamine synthetase family protein"
                     /protein_id="WP_014984678.1"
                     /transl_table=11
                     /translation="MEAVEQFLKENSITMVELATPDMTGALRGKRIPVESFLANGMSDG
                     VGLSSAVLAWDYRMEVIETADYSWSNGYPDIFLRPDVATLRLVPWKPKTALVFCDVVDA
                     AGELAAIAPREVLRCVVADVENAGLAPYIAMETEFYALDGESLRARGDRNPVYSLHDNH
                     YLEPFLDEICAMLLSADVEVEACGAEYAPGQVEINLTPSDPVTAADSLLFFRYAVKQLA
                     PRHGYRATFMAKPFGDLSGSGLHIHQSMWGQDKSNAFWDARTGGLSAVGGNYVAGLLKY
                     AAELQLVAVPTPNGYKRVTDHSFAPTNLSWGLDNRCAAVRVLIRDAKGTRVETRIAAAD
                     ANPYLLAAAQLAAGSAGVTEGLTPAEPAANSYVSEEYSPLPTNIWAAATLFGESEFARR
                     ALGTGTVQNLYQVARSEAAAGQREVTEWERARYLDSV"
     misc_feature    38939..38955
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            38945..40942
                     /gene="asnB"
                     /locus_tag="O3I_RS19490"
                     /old_locus_tag="O3I_019325"
     CDS             38945..40942
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /locus_tag="O3I_RS19490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019325"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_167829156.1"
                     /sec_met_domain="GATase_7 (E-value: 1.1e-39, bitscore:
                     134.0, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 9e-67, bitscore:
                     225.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGVVGFIDSGLRKDQRLDLVRRGIRAIAHRGPDEVGLYDSADFT
                     LGTVRLSVIDPRLGQQPMVTPDQRYIAGFNGEVFNYLELRSELEGYGVRFRTNSDTEVL
                     LHSFAYWGLDALSRLNGQYGFVFYDKWERTLILGRDRFGERPMFYTEQDGTLYFASEIK
                     GLFAFPRVPRELAADKVRRAMRYWSPVPGETCFTGIDAIPPGHILTVRDGQAELSKYYH
                     GIARQDAVAPPKSFEEAKSGLREVIRDSVRLRLRGDYPLGTYISGGIDSAVISSVMSEL
                     IGEPLTTFSIDAADSPVDESPYQQAMVDRLGSRHTRIPVSRAQVRERFPHVVRQCEQPL
                     HFTAPVAYGVMAEHVGLAGVRIILGGEGADELFAGYDVAKEATILERCLRGGSFAGAAE
                     ELELALNDMRYSDATNAAAILRFYADRADRDFTLGAHLRRFETEPVDQLIAATGDVYDD
                     HAVLLRRLRTEFPDFDRRPAIDRSMLVDMHTFLIGYGMTCLGDRAGTGYGVEGRYPFMD
                     SHVVQYAAALPVDWKLNGARAKHILREAYSDRLPHGIVNRPKFGMRLPGAEALLPDGDD
                     WVAAVLSPSTIKRVGFLVPEAVDRLVDRVTGSRSPRVPYPFGDAYVHLLSVLLMEEFLI
                     HDFQVPEVDIDRIMMRDIDGDHDPVGTAAR"
     misc_feature    38978..38980
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            40966..42363
                     /locus_tag="O3I_RS19495"
                     /old_locus_tag="O3I_019330"
     CDS             40966..42363
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012503.4"
                     /locus_tag="O3I_RS19495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019330"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_014984680.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 0.00025, bitscore:
                     19.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHVDLVDDVREVGTAVLEALVAHVESVRAGSGEVVSAADIDTVS
                     KRLELRRWVEEGGMTLPELLSFVTTYSDISASHHHPGYMGHQIAPSDTPGVVADLLQAV
                     TNNIPLVYELAPAAAAVDRAVCRWMLDHVGWGETGLGAITNGGTLGNLTALLAARSHAD
                     TTAWQRGTPGDLVILAPATSHYSVRKAAAVMGLGVNGVYPLRTDALGRIDPAGLAPALA
                     DVRAQGLRPVAVVANGCATGTGLYDPIAEVAQFCDANGLWLHMDGAHGAAALLSPRLRG
                     LLAGLERADSTVWDGHKMLRTSALCTGVLFREKRYLDTMFKQDASYLYRPEAEDVDPGQ
                     YTFETSKAPLGLKVLLTLAYRGEASLRSYVERQYGLATELWELIQERPDFTAPYQPQSN
                     ILCFRYEPCGDRQLELRARLIQDGRFYLSSFRLGGRPYLRASLMSPTTDRETLHQLLEV
                     ITKVAAV"
     misc_feature    41551..41553
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(42375..42385)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(42435..42453)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.38"
                     /tool="antismash"
     gene            42480..43856
                     /locus_tag="O3I_RS19500"
                     /old_locus_tag="O3I_019335"
     CDS             42480..43856
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983986.1"
                     /locus_tag="O3I_RS19500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019335"
                     /product="cytochrome P450"
                     /protein_id="WP_014984681.1"
                     /sec_met_domain="p450 (E-value: 7.1e-77, bitscore: 258.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEQGAAVVATAPHRLPVLGHLLSLLRDPLGFMASLPAHGDLVRI
                     GLGPVTAVVVCDPDLTQQMLRQDRIFDKGGPQFDRGRELVGHGLATCPYAMHRRQRRLL
                     QPAFHADRITGYAPMMTYQITEMVDSWRDGEVIDVKAQLHTLAAKVTAATLFGQAMPES
                     DQQRLLRDVEVVFAGVIRQAMMPEWVRRWPVLGNRACLRAAEEARAILGELVAARRAEG
                     VDHGDLCSALVMARDNDGGQLSDGEIVDQVLTFFFAGTDTTATALAWALIQLDRHPEVA
                     ARLHAEVDAVLAGAAARHGDLPRLPFTGQVIAETLRLRPPAWLSTRTVTEDTELGGHPL
                     PAGSTVIFSSYLIQHRPDLYPDPERFDPDRFDPARPEPPRDAQLAFAAGARKCIGDRYA
                     LTEATLALATIATRWRLRSLRGTDIRPTLAVVPEPRRLRMRATARTPRSARAEEPGQLV
                     "
     gene            complement(43905..44510)
                     /locus_tag="O3I_RS19505"
                     /old_locus_tag="O3I_019340"
     CDS             complement(43905..44510)
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019050559.1"
                     /locus_tag="O3I_RS19505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019340"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_014984682.1"
                     /sec_met_domain="Abi (E-value: 8.3e-09, bitscore: 34.7,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAGLLARRRRVAVVALAGTGLLGASFAAEPDSARFYRLTLATA
                     ATWTLGGRTPPDGERPAPVLAPIALGAATFAVFYGCGLIARRIPFLRKAITGVLRYAER
                     GPTPRVLLITLANGAAEEIFFRGAVYAVAGRHPVLASTGVYACTTAATRNPALVLASVL
                     MGTLFGLQRRATGGVQAPMLTHLTWSTLMVQYLPRLFR"
     gene            complement(44507..45403)
                     /locus_tag="O3I_RS19510"
                     /old_locus_tag="O3I_019345"
     CDS             complement(44507..45403)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018160075.1"
                     /locus_tag="O3I_RS19510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019345"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_014984683.1"
                     /transl_table=11
                     /translation="MTVLVAGSTGFVGQRLCPELAATGRPVRAMTRHPESYRGSGTPIG
                     ADVGDPDSLRAALRDCDAAYYLVHSLAEADFRRRDAAAARNFGRAAADAGVRRIIYLGG
                     LGDDTDDLSAHLRSRREVEGLLGAAGVPVTTLRAGIIVGHGGISWEITRQLVEHLPAMV
                     TPRWVRTRTQPIAVDDVVRYLVGVLDNPETTGRTFEIGGPDVLEYLDMLRRVAEIEGRP
                     LLVLPVPLLSPRMSSLWLSLVTDVDTTTGRALVDSMTNEVVVRDNSIRELVPFDPLDYD
                     AAVLRALGERAKAARAA"
     gene            complement(45635..46237)
                     /locus_tag="O3I_RS19515"
                     /old_locus_tag="O3I_019350"
     CDS             complement(45635..46237)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019045535.1"
                     /locus_tag="O3I_RS19515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019350"
                     /product="hypothetical protein"
                     /protein_id="WP_014984684.1"
                     /transl_table=11
                     /translation="MTTAQLAAPLAPAPVRSRSGDVDNRSTYVSFGLAYILGHGAAALS
                     RGADPLLALPAWLPLALLGMGFAVGTVSATRAALRAQRGAAEPDVRTGQLLGLSWAVGF
                     GALFVAITGLTATAGLPELQSVLWPAGSGLVVGLLYLGEGAARRNVLHYGLGAWLALVS
                     TAALFVGMPGFFAILAIAGGGGYAVATALEYRRLALH"
     gene            complement(46301..47347)
                     /locus_tag="O3I_RS19520"
                     /old_locus_tag="O3I_019355"
     CDS             complement(46301..47347)
                     /NRPS_PKS="Domain: PKS_ER (20-342). E-value: 1.3e-38.
                     Score: 124.8. Matches aSDomain:
                     nrpspksdomains_O3I_RS19520_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019045536.1"
                     /locus_tag="O3I_RS19520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019355"
                     /product="medium chain dehydrogenase/reductase family
                     protein"
                     /protein_id="WP_014984685.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.3e-18, bitscore:
                     64.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNSTATITAIVLPDRVEPDGLQVTTRDLPTPAAGQVVLGMEATG
                     VSFAEQQMRRGKYFDQPSFPFVPGYDVVGTVTATGPGVDTGLIGCRFAAVTKVGAWSSA
                     LVLDAADLVPVPDGVTPAAAETVVVNGLTAWQLLHRTARVRTGATIVVLGANGGVGSTL
                     VQLARQAGITVIGTAAPRHHAALREQGVTPVDYRDPDMYARIREVAPDGVDAVFDHVGG
                     ATVVDSWRLLRRGGTLVSYGTAATKNADGNPKLPVLKLFPRLLLWNLLPNGKSARFYNL
                     WAGQRRLDIFRRQLREDLTQVFRLLAEGALTPQIAAEFPLSEAAAALTLAESHTVAGKV
                     VIVPDAHR"
     aSDomain        complement(46322..47287)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS19520_PKS_ER.1"
                     /evalue="1.30E-38"
                     /label="O3I_RS19520_PKS_ER.1"
                     /locus_tag="O3I_RS19520"
                     /protein_end="342"
                     /protein_start="20"
                     /score="124.8"
                     /tool="antismash"
                     /translation="GLQVTTRDLPTPAAGQVVLGMEATGVSFAEQQMRRGKYFDQPSFP
                     FVPGYDVVGTVTATGPGVDTGLIGCRFAAVTKVGAWSSALVLDAADLVPVPDGVTPAAA
                     ETVVVNGLTAWQLLHRTARVRTGATIVVLGANGGVGSTLVQLARQAGITVIGTAAPRHH
                     AALREQGVTPVDYRDPDMYARIREVAPDGVDAVFDHVGGATVVDSWRLLRRGGTLVSYG
                     TAATKNADGNPKLPVLKLFPRLLLWNLLPNGKSARFYNLWAGQRRLDIFRRQLREDLTQ
                     VFRLLAEGALTPQIAAEFPLSEAAAALTLAESHTVAGKVVI"
     CDS_motif       complement(47108..47143)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19520_0002"
                     /evalue="5.40E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="O3I_RS19520"
                     /protein_end="80"
                     /protein_start="68"
                     /score="6.8"
                     /tool="antismash"
                     /translation="GYDVVGTVTATG"
     CDS_motif       complement(47210..47233)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_O3I_RS19520_0001"
                     /evalue="6.70E+00"
                     /label="PKSI-ER_m2"
                     /locus_tag="O3I_RS19520"
                     /protein_end="46"
                     /protein_start="38"
                     /score="0.5"
                     /tool="antismash"
                     /translation="LGMEATGV"
     misc_feature    complement(47352..47366)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     misc_feature    complement(47418..47433)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.38"
                     /tool="antismash"
     misc_feature    47426..47442
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.06"
                     /tool="antismash"
     gene            47456..48097
                     /locus_tag="O3I_RS19525"
                     /old_locus_tag="O3I_019360"
     CDS             47456..48097
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014984695.1"
                     /locus_tag="O3I_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_019360"
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_014984686.1"
                     /transl_table=11
                     /translation="MNEANRATHIRVRNPRGEGARLRDEIVAAAVALLDETGDGSALTL
                     RSVARRAGIAAPSIYRHFPHQSAIMPAVVRDAFAQLDAQLRAAVRAAGDSPRDRLAAVC
                     FGYLEFARARPGRYRIMFGGGWVPDRDDGAVSEGEMAVLGQSSLRLLAAALTDCVAAGQ
                     ARSADPAVDAVALWLGLHGLAHQRAVAPSFPWPAGIVERLVSTLAHLTAP"
     misc_feature    complement(48222..48235)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.41"
                     /tool="antismash"
ORIGIN
        1 gcgtctcgcg gtccagcggg cgcaggctgc gcagatcgat cacttcggcg gaaacaccct
       61 cggcggcaag gcgttcggcg acctgggtgg cgacggtggc catccgggag tagccgatga
      121 gcgtgatgtc ggtgccggcc cgggtgaccg cggccttgcc gatctgcgcg gccggaaggt
      181 ccaccggcac ttcgcccttg gtgttgtaga gcgacaggtt ctccaggaac aggaccggat
      241 cgtcgtcctc gatcgcggcc ttgagcagtg cgcgggcatc ggcgggcgtg ctcggcgcca
      301 ccaccttcaa gccgggcacg aaggcgtagt acagctcgat gttctgcgaa tgcgtcgcgc
      361 cgagctgctg gccgccgccg cccggcgtgc ggatgaccat gggcacgctg gtctgcccgc
      421 cgaacatgcc gtagatcttg gcggcgtggt tgacgatctg gtccagcgcg agcagtgaga
      481 agttgatcgt catgatctcc accacggggc gcaggcccag catggcggcg ccgatcgcgg
      541 cgccgacgaa accttcttcg gcgatcggag tgtcgcgtac tcgcttctcg ccgaattcgg
      601 cgagcagtcc ggcggtgatc ttgtaggagc cttcgaagac gccgatctct tccccgatca
      661 ggaagacgtc gtcgtcgcgg cgcatctcct cacgcagggt ttcgcgcagc gcttcgcgat
      721 aggtcatgac aggcgctggg ggatgggtag gcacagttgg tcctcagacg gtgaagagcg
      781 ggtcggcggg cagacggcgg gagtcgctcg ggaccggcgt ggcgtagttg tagtcgaaca
      841 ggctcgacgg gtccgggtgc gggctcgcat cggcgaattc caccgcggcg gctacgcttt
      901 cggtcacctc ccgttcgatc tcggccagcg actgatcggt gagcacgtcg gcggcgagca
      961 atcggtgctg ccacagcgcg atcggatcgt gttcgcgcgc cgtggccacc gcttcggtgc
     1021 tgcggtattt ggccgggtcg accaccgagt ggcccttgag ccggtagctg accgcctcca
     1081 gtagcgccgg tttcccttcg cggcgtgcgg cttcgatgag ctcgctcgcc atatcgcgca
     1141 cggcgagcac gtcggtgccg tccacccgtt cgccgcgcat gcggtaggcg gcggcccgct
     1201 tccacagatc cggctcggcc gaggagtgct cgaccgtggt gcccatgccg gtctggttgt
     1261 tgatcaccag gaagaccacc gggagccgcc acagcgcggc gatgttgagc gattcgtgga
     1321 acgcgccgat attggtggtg ccctcgccca tctggcacac caccacgtcg tccccgccgc
     1381 ggtagtcgat ggccagggcc gcgccgatgg cgagcggaac ctggccgccc acaatggcgt
     1441 agccgcccag caggcgggtc gcggtgtcgt acatgtgcat cgagccgccc cagcccttgg
     1501 aagtgccggt ggcgcggccg tacagctcgg ccatcacccg gcccggctcg atgcctttgg
     1561 ccagcgcgta accgtgctcg cggtagttgg tgaacaggta gtcggtgggc cgcatcgcgg
     1621 cgccgaggcc gaccacggtg gcttcctcgc cgaggttcag gtggcagtag ccgccgatct
     1681 tggcctgctg gtagctctgc gcggtgcgct cttcgaaacg ccgcacgaac agcatgtcgc
     1741 ggaacaggcc gcgcaggatc gcgggatctt cggtggcgaa ggcggattcg gcggtgacgg
     1801 gcgcggactt ggtggttcgc cgcgtggttt tgcgcggagc gctcgtggtg gtcatctgcg
     1861 gctcctaacg cttacgcggc gcgatgtgca ccggcagtcc gagcccggcc agcgccgtct
     1921 ccatgccgat ctcgccgagg gtggggtggg cgtgaatggt gtcggccagc tcgtcgagcg
     1981 tcgcctccag ggcgatggcc agcgcgccct cggtgatcag gtcgctggcc gacggaccga
     2041 tgatgtgcac gccgagcact tcccgatgct gttgcccggc aacgatcttc atgatgccct
     2101 cggtgtcgcc gaaggttttc gcccggccca gcgccgcgaa cgggaacttg gcggtgatca
     2161 cctcgtggcc ggccgcccgc gcggccgcct cggtcaaccc gacgctcgcg atctccggat
     2221 gggtgaaggt ggccgccggg atcaccgtgt agtcgatgtg cgcgtcgtgc ccggcgatca
     2281 cgtcggctgc ggtgaggccc tggtgcgagg cgacatgggc gagcagtgcc cggccggtga
     2341 cgtcgccgat ggcgtagacg tgctcgaccc cggtccggag ctggtcgtcg acctcgatga
     2401 aaccccgtgc gtccgtgccg attccggcga tgtccagacc caggtccgcg gtgttgggcc
     2461 ggcggccgac cccgaccagt acgacgtcgg cggggatgtc ctgcggcttc ggtccggcga
     2521 ccgagacccg caatccgtcg tcctgcgcga tcgcggtgac agtggctccg gtgagcacgg
     2581 tgataccgcg tttgcggaag gaacggccga gcgcgtcgcc gatctccttg tcctccagcg
     2641 gaacgaggcg atcctgcatc tccaccacgg tgacctggct gccgaacgtg gcgaacaggc
     2701 tggcccattc cgcgccgacc gcactgccgc cgatgaccac caggcgtcgc ggcacgtcgg
     2761 tgagcccgaa cgcgccgtcg gaggtgacga caccgggcag gtcggctccg ggaatcggca
     2821 gcagcgcggg caccgagccg gtggcgacga tcacgtcctg cgcgctgacc tggcgcaccg
     2881 gcgcgcccgg cgcggcggcg tagcggggac cgccctcgaa gatgggggac gcgccggtct
     2941 cgtgcacctc gaccgtggtc ggcccgacga accgggcatg gccctcgatg accgtcacgc
     3001 cgttggcctt cagcaggccg gcgacgccgt cggtgagttc cttgacgact ccgtccttac
     3061 gctgccgcac ggccgcgaag tcgaagcgca cattgtcggc gtagacgccg aattccgctg
     3121 cggcggtgag ggtgtggaag acctcggcgg aacgcagcat cgccttggtc gggatgcagc
     3181 cccagttcag gcagacgccg cccgggcgct ccttctccac caagccgacc cggagtccgc
     3241 gctgcgcgcc ccggatcgcg gccacgtagc cgcccggtcc gccgccgatc accagtagat
     3301 cgaattccgg cactcgtggt gctcctcatc tcgacgatta gcgacccggc cgggttgtgg
     3361 cgcgggtcgt tctctcgagt cttgtgggcc gcgattgccc aagcaatttg ccggaagccc
     3421 agaaatcggg gcgcgaaaat gggcgcagcg cacaatcgct gcgggccgct cagtccgatt
     3481 cggccgcacc cagctcgact gccgccagcg cgagcgacag ctcgagatag gcgcgttggc
     3541 cctcgagcgg acggcccagc agcgtggcga tgcgctgcag ccggttgatg acggtgttgc
     3601 ggtggcagtg cagcagcggc gcggcattgg cggccgaaca gttctcggcc agccaggcgg
     3661 ccagcgtctc cagcaggatc tcgcgttccc gctcgggaag ggcgagcacc ggtccgagcg
     3721 tgcgcgtcac cagcagttcg gtgagatcgg gggagcgcaa cagcatcgcc tcggggtagc
     3781 gctcctcgag tagaaccaaa ccctgtgcgt ccgtgggcaa tgtctccaag gcgagcatcg
     3841 ccagcgcgtg cgcggtatcg atctgggcca gccccggcac cgggggcgag gccgcggccc
     3901 cgccgcggag ccgcggccgg atctgttgca gcacagtgga actgtcgtgc cgctcgagtg
     3961 aaaccaggcc gaccgtggcg tccacccgat cgtgccacac cgagcgaata cccaacgccg
     4021 ccaacgcggt ctcggtaccg agctgcacgg ccggccggcc gcgcaccgcg accatgaggt
     4081 aggcgccgtg ggtgggcagg ttcagttcgc gggcggcgcg cgcggcgaag gtcgcgtcgt
     4141 gtgcgcggcc ggccagcaga tcttcgatca acccgtgcct gcggcgctcg tcccggcgga
     4201 cctgctcgag ttcggtattg cggtaggagg tgaccagcgc cgaggacatg ccgtcgatga
     4261 ccgaccaggt cgccgcgccg atctcgcgga actcacccgg tgccaggtcg tcggcgtggt
     4321 cgagcagtgc ctcccagacg atctggccgc ctagccggaa cgtccgcagc atcacctcca
     4381 gcggcacgcc ttgcgccgcg cggttgcggc cgatggcggc ggcgacatcg tcacggtccg
     4441 gcacggtgac atcgccggcg agcaggtcca gcacccgggt cagatagctg cggcagccgt
     4501 tgcgcagatc ctcgcggctg acgggtgagt aatccgtcca ctcggggata tcggtgaaga
     4561 tcgccgccat cagccgccgc gtcagcaccg gaacctcggt ccggcacacc gcggccagtc
     4621 gccggatgcc cggcgtcggg ccggtgtgct tgggtgctgc cataggcatc aacctacgcc
     4681 gcccggtatg caccctttcc ggctgcacgg aagcgagtca ccaggtgctt tggtgcggca
     4741 cgccgtggag gagggcggtc tcggcccaga gccacgcggc gaccggaccc gtgaaaacgg
     4801 tcgcgatggt ggacaggtcg ggcttcagtg cgaaaagcat gtcgatcaac tccgttgtct
     4861 tacagcgaac tttcggaccg ggcgggtgca gtgcgcgcgg tcgtcacctg gcctgcaaag
     4921 ggcgggcgaa cgacttgcgc agcgaggccg ggcccaccag cgggagcagt gcggcgagga
     4981 ccttggcttt gaacgcgtgc ggcgtgcggg tcagctcgac gtcgacgcgc gtgccgtgct
     5041 cgtcgggggt gagccggaag acccagccgc cgccgggacc gaagagcttc gagtcgagcg
     5101 tcgtgacggt gacggtgtcg cccgccggat cccactcgta gcgggcgcgt tcccaggccg
     5161 cggcggtgcc ctcggtcacc tcggcccagc tgtcgccgcg ctcgtggacg acgaaatgct
     5221 cggcgtcgat gctcggccac gcctgtgggc gggacggccc gaaatcggtg agcacatgcc
     5281 ggacctgtgc cggtgccagg gtggacagga ggtggaaacg aacgatagcc atgcttcgac
     5341 gatggctgtc gcggcggcgt cgccgaatcg gtcagatgac gctgccggtg acgtaatcgc
     5401 ggttcggtag ggtcgcgggc gggcctgcgg atcgacgcgg acctggcgaa aggggtaccg
     5461 cggcatgccg atgttcggcc gagacaccga gctgaaggcg ctgcgcgcac tcgtggacgg
     5521 gcccggtgag cagtccggca tcctggtcga gggggagccc ggtatcggga agtcggccct
     5581 gatcgaggag acggtcgccg ccgcggccgt ggcggggctg cgggtattgc gcaccgctgg
     5641 ggccgaggcc gagctgaact cggcgtacgc ggggctgcaa cgcctgctgt accccctgcg
     5701 ccggggtttc ggcgaactcc cggcgccgca gtccgcggcg ctggcgagcg cgctcggaat
     5761 gtcggatgcc ccgggtgcgc cgaacggcta tctggtcggg ctggccgcgc tgacgctgtt
     5821 ggcggacgcg gccgccgatc gtccactgtt gatcatcgcc gaagacgtgc actggctcga
     5881 tccggccagc gccgaggtgc tcgcgttcct cgcgcgccgg atcgaggccg agccgctcgc
     5941 gctggtcgtg acgtcgcgcg cgggcggcac cccgctcgcc gactcggggc tgaccccgat
     6001 gcggctcggc gggttggccg acgacgacgc cgcggcactg ttggacagtg ccgcaccgga
     6061 tctggccgcg ccggtccgcc gccgagtact ggcagcggca caggggaatc cactcgcact
     6121 gagcgaactg gcaacggcga cagtggatct gaccgggccg atgcccttga cggaacgcct
     6181 cgagcgggcc ttttccgcgc ggagtgtgga gctgccgccc gagagcaggt ccgcgttgct
     6241 cgtcgcggcg ctcaacgaga gcgactcgat cgccgaaaca ttggccgccg taagcattct
     6301 ggcgggatcc ccggccgacc ccgaaatcct cacacccgcg cggacggccg gactcgtcga
     6361 aatggattcc ggcacggtga cattccggca tccgctgcaa cggtcggcgg tcgccgccgc
     6421 ggcctcggcg caggaacgcc gccgtgccca cctcgccctg gccgatgcgc tcgatgccgc
     6481 gccggaccgg cggattcggc accgagcggc gggcacgctc ggccccgacg agcacctcgc
     6541 ggtcgagctg gagcaggctg ccgagcaggc ccggcaccgc gccggcgcgg tcgccgcgct
     6601 ggaacgtgcc gcggcactga gcgatacccc cggcgggcgg gcggaccggc tgttgcgggc
     6661 cgccgaagcg gcggtcgatg ccggtcgccg cgatagcgcc gaacggctgg tcgcggccgc
     6721 tcgcgcgtta ccgctgacgc cgcgccacca ggccaccgcc aactggctgc tcagcggttt
     6781 cgacgacggg gtacgcgaaa gccccgcgcg ggtcggcgaa ttggctgcgc tcgcatccac
     6841 tgtcgcggct gcggggtaca ccgacgccgc cctgcggatt ctgtggggcg cggccatgcg
     6901 gtgcttctgg gtcgagcccg gccccgagac ccgccgggcc ctgctcgcgg tcgccgatgc
     6961 gctgccgatt ccggacgagg atccgcgcat ggtcgcgatc aacgcgtatg tggcgccgtt
     7021 cgatcgcggc gcacgcgtga tcgagcggct gcgcgggttg gcggcgcaca cgggccggga
     7081 tccggaggtg gatcggtttc tcggtagtgc cgcgctgcag gtgggcgcgt tcgacctggc
     7141 cgcccggttc gccgcggccg ccgcacccgg actgcgggac gcggggcagt tgggtctgct
     7201 cccgcgcgcg ctgaccgtgc agtcctggag cctggcccgg ctgggtgatc tcgcggcagc
     7261 cgccccggtc gccgcggagg ccgtggatct ggcgcgcgaa accggccagc cgttcatgca
     7321 cggcctggcc atcgcggtgc aggccgagat cgccgccctg cgtggggatc atccgcaagc
     7381 ggcggcactg gtggcggaag cggagcggat cgggctcgcc gcgggcgcgc gtcccgtgct
     7441 ggccaccgtg cagctcaccc gcgggctcat cgccctcggc acgggccgat tcgacgacgc
     7501 gtgcgccgac ctgctccggc tgcacgaccc gcgcgacccg gcgcacgcgc cgttcttgcg
     7561 cgcgtacttc ctgaccgagc tggccgaggc ggccgtgcgg gcggggcggg tcgaggcggt
     7621 gcacgacctg atacgcgagt tggcaccgat tgcggcggtg acgccgtcgc ctgcgctggc
     7681 gatcggaatg cgttacgcgc aagcggtatt cgcgaccgca gcggtcgagg agcggttcgc
     7741 ggcagcgctg tccgcggatc tcaccggctg gccgggtgag cggggccggg tgcacctggc
     7801 gttcggtgaa tggttgcggc ggcagcgccg gatcgtcgag tcacgcaccc agttgcgtac
     7861 ggcccgtgac attttcgacg cactgggctt caccgcgtgg agcgaacggg cccgggtgga
     7921 actgcgcggc gccggggaat cgagtccgga tcgcagcccg gcggcccggg aacggcttac
     7981 gccgcacgag ctgagcatcg cccaattggc ggcgcagggt ctgaccaatc gggagatcgg
     8041 gcagcggctg ttcctctcgc atcgaacggt cagcacgcat ctgcatcgca tcttcccgaa
     8101 gctcggcatc agcgcacgag gcgacctcgc cgcactgctc ccgggcctga acgacaccac
     8161 gcccgatcag acgtgaccga caccgattac gtcatctgac gctcgccgcc gcaccggcgc
     8221 actgcctaac gtcggcgatg cggacggtgc cgaggtgcag gccctggtcc cgaccgcgta
     8281 tcggaccagg gacgaggagc tcagatggat atcagcagac gattcttcgg tggggcgctg
     8341 gccgtgggcg cgacgagcct ggccgtggcc acgctgagcg cctgcgccac cgatccggcc
     8401 gcgagctcgg ccaccacgcc ggcgtcgccc ggcgcggagc tgcgggcggg ctcgggtgcc
     8461 cacaccacgc tcggcccgat caaacaaatc gaagcaggcg ccctgaacat cggctatgcc
     8521 gaattcgggc cgagtaccgg ccgacccgtc atcctgctgc acgggtggcc ctacgacccc
     8581 tacagcttcg ccgatgtcgg accgctgctg gccgcggccg gatatcgggt gctggtcccg
     8641 ttcctgcgcg gctacggccc gacgaccttc cggtcaccgc aggcggtgcg caacgggcag
     8701 cagtcggcga tcgcccgcga catcgtcgac ttcatggacg cattgcggat cgatcaggcg
     8761 gtactgggcg gattcgactg gggcgcaaga acggtcgaca tcatcgccgc gctgtggccg
     8821 cagcggtgca aggcgatcgt cgcggtgagc ggctacctca tcacccagca ggcggcacag
     8881 cagcagccgc tcgcgccgga agccgaactg ggctggtggt atcagtacta cttcgcgacc
     8941 gagcgtggtc gcgtcggata cacccgcaat cgccacgagt tcaacaagct gatctggcgg
     9001 cgggcctccc cgcagtggaa cttcgacgac gccaccttcg accgcagcgc ggccgcgttc
     9061 gacaatcccg accacgccga gatcgtgatc cacaactacc gctggcggtt gagcctggct
     9121 tccggcgagg cccgatacga cgagtacgaa cagcaactcg ccaccggccc ggtgatcacg
     9181 gtcccggcga tcaccatcgg cagcgacttc gacggtgccg ccaaggacgg aaaaccgtac
     9241 cgcgacaagt acatcggcaa gcacgaacac cgggtgctgg acggcatcgg gcacaacgtc
     9301 ccgcaggagg cgccacagcc cttcgcgcag gcgatcatcg acgccgaccg actgtgacac
     9361 ggtagaaccg gcggcctcgg tcgcgagacc gccggtcacc gcgcgctaca gcgaggcgtg
     9421 cggctggaaa cggccgtcgg cgtcgagtgc gacgacggtg tcgatgccga tccgccgcag
     9481 gaacggatag tcgtggctga ccaccaagag cgcgccgcga tagtcggcca gggcctcgac
     9541 gagctggtcg acagaggcga tgtcgaggtt gttggtcggc tcgtcgagga tcagcaactg
     9601 gaccggcggg tcggcgagca gcaagcgcgc cagcgagact cggaaacgct caccgccgga
     9661 caggctcgac accgggcgtt cggccgcggc gccgcgcagc agcagccggg ccagctgatt
     9721 gcgaatggtg ccgggcgggg tggtgacggc caccgcgtgc acgttctcga tcgcgctggc
     9781 ttgctcgtcc aagccgtcca ggcgttgcgg gaggtatccg acgcgatcgg tcaacaggac
     9841 gccgcgctcc ggtcgccggc cgtgcacgag atcctcgatg agcgtggact tgcccgcgcc
     9901 gttgggcccg atcacggcga cccgctccgg cccctggatc gtgacgccgc gatcgccgtc
     9961 gcgcagttcc gcgatgcgcc tgctgcgggg cacgtcggga tcgggcaggt ccaggtggat
    10021 gtgctcgtcg gagcggaccc gcgccgcggc ggcgtccagc acctcttggg ccgcacgaac
    10081 tttggcgtcc agtgtggtgc gcatggcgcc ggccgaggcc tgtgccttgc tggcacggtt
    10141 gcccgccagg atgcgcggta tacccccgtg ctgctgtgtc gcgcggcccg tgcgttcgcg
    10201 ccgggccagc ttggtctcgg cctcgatgcg ttggcgtttc tcgactttca gcgcctgctc
    10261 ggcggtccgg gccgcctggg tcgcggccgc ctgctgttgc tcgacgtagt cgcgccaagc
    10321 gctgtagggg ccgccgaaca cgtccagggt cgcgccgtgc aattcggcgg tggcgtccat
    10381 gtgctcgagc agttcgagat cgtgactcac caccacgagg gtgcccggcc acgcgtcgac
    10441 gaacgcggtg agctgggcgc gagtttcgcg atcgagattg ttggtcggct cgtcgagcag
    10501 cgtgatcggc ttgcgctgga cgcgcaggcc ggtgatcgcg acgaggaccg cctggccgcc
    10561 ggagatcgca ccgacggtgc gatcgagatc ggctgcgccg aaacctattt cgtgtagcgc
    10621 ctcgtcggcc cgggcctcga tgtcccagtc gtcgccgatc gtgtcgaaat gcgcggcgtc
    10681 gctctcgccc gcctcgatgg cgcgcagcgc ggcgagttcg tccgcgatgc cgagcagttg
    10741 ggcgatggtg gcgtcgcgtc cgagggtgag ggtctgcggt aggtatccga catcgccggt
    10801 ggtttcgatg cgcccggacg tcggggtgag ttgtccggcg atcaggcgca gcagggtcga
    10861 cttgcccgcg ccgttgcggc cgaccaaacc ggtgcgaccg gtggtgaagg cgccgtcgac
    10921 gccggcgagg gcgacggagc cgtccggcca ttcgaacgtc agttggtgca gagcgattgc
    10981 cgaggtgatg gacatgcgtc agtggctctt cctgctcgcg agcgagcggc agcgaggtga
    11041 gaacagattc ctgtggctgc cggcgaaggg cgcggccgta ctcgaacgag cacgtgtatg
    11101 aggagcgccg ccttcgaccg ggcggctagc gtctgtcgac ctcgatgagc acgtgctcag
    11161 cctatcagtc gcgggccggc cgcccgagcg acgcttccgg cgcggctgcc ggggtggggc
    11221 cgtggcggat ggttccatgt cggccatgga cccagcggtg cgtgccggcc gggcacagaa
    11281 gacctggttc tttccctcga cctacacgat cctcgccggt gtcgccttgc tggtgtggct
    11341 cgcggcgttc gtgattccgc cgggggccta cgacaccgat gcgcgcggcc gtccgatcgc
    11401 ggggacctat caccgcgtca tcgatgccaa ggggttcggc gagcggttgc gggagctgtt
    11461 cctcgcaccg gtcaacggtc tctacggcat tcaggacgac aggtcgggtc aggtcggtcc
    11521 ggacctgacc ggtcacctct acggcgcggc cgcggtcttc ctgttcgtgc tggcggtcgg
    11581 cgcgttcatc accgtcgcct tcgcgaccgg cgccctcgac agcgggatcg ggcaactggc
    11641 ccatcggcta cgtgaccggt ccgcgctgct gatcgtcggc gtcatgctgg tgttcgcgat
    11701 cgcgggcacg gtcgagggct tcgcggagga aacgctcggc tgctacgcac tgctggtgcc
    11761 gttgctgctg gcgctcggct acgaccggat gacggcggtg ggcacgatca tctgcggcgc
    11821 cggcgtcggc atgctgtgct cgacggtgaa tccgttcgcc accggcacgg cgtcctcggc
    11881 ggccggcgtg cccctcggcg aggggatcgg gctccggctc gcgatgctgg tggtgctcac
    11941 cgccgtcacc gtcggctatg tgctccggta cgcggagcgg gtcaaacgcg atccggcgaa
    12001 gtcctggtcc ggttggcaac ccggcgaccg cgaaggatcg gccgacgacc atcgccctga
    12061 cccgctgacc cggcgtcagc aagcggtgct ctggttggtg gcagcgactt tcgcgttcat
    12121 gatcttcgcg atcatcccgt gggcggaggt gatcgacgga cccggcgccg agcgctaccg
    12181 ctggcaattg ggttggtatt tccccgaact caccgcgctg ttcctgttgg gcgcggtggt
    12241 ggtgggactg gtcggcgggc tgggggagaa cagggtgtcc gaggccatcg gcaagggttt
    12301 cggtgacttc gtcggcgcgg gtctggtgat cgtgctggca cggggcgtga ccgtcatcat
    12361 gaacaacacc gaaatcacca gcaccgcact gcattccctg gaaggcctgg tgaccggtac
    12421 ctcgtcgacg gtgttcgcgg tcacggtgtt tctggtgaac gtgccgctgg gtttcctgat
    12481 tccctccagc tccggccatg ccacgctggt catgccgatc atggcgccac tcgccgattt
    12541 cgcgaatgtg ccacgctccc ttgtggtcac cgcgtggcag tcggcgtcgg gctgggccaa
    12601 tctggtcacc ccgaccacgg cggtggtgac cggcggtctc gccctggcga aggtgcgcta
    12661 cgaccgctac gtgcggttcg tggccccgct gctcggcatc ttgggcgtgc tgatctgtgg
    12721 gttcctcgcg ctcggcgcct tgctccggta gtcggcggcc gagggcagca gcagcggggt
    12781 ggcgagcagc agcacgccgg agatcgtgat cgcggtgtgc gggccggtgc aggtggcgag
    12841 cacgccccag agcatcatca gggttgcctg caacaatttc gcgcaggcat tccaggtgct
    12901 cagcacgcgg gcggcgtggt cccggggtgt gcgccgcagc cgggcggtcg cgtagagcgg
    12961 attgaagaca cccatgcacg cgatcaagag cgcctcgacg ccgatcacgg tgagcagtcc
    13021 gggaattccc ggctggacga aggccaggcc gagcgggaag accgaccgca accagccgga
    13081 gacgagcatg acccgctgct cgccgtagcg gcgggccagg tggcctgaca ggcgcgcgcc
    13141 gacgaaaccg ccgagtgccg gaatcccgaa agcaagaccg tattgccatg cggggaagtg
    13201 atattcgccg agcaacagga ccgacagcag cgggacgcct gccatgatca agccgctgac
    13261 cgagatcgag ttgaggaaca agcgcaccag gacccggtcc cgtcggatgt aacgccagcc
    13321 ggtgagcagg ccggttcgcg gtggctcggc gcgcggcgtg gcgatatcgc cgccacggat
    13381 ccggcgcacg gcgcacgcgg acagcagaaa gctgaccgcg tcggtggtga tcgtgacgac
    13441 cgggccgaac accccgatca gcgcaccccc cagcggcggc ccgaccgcgg tcgccaccca
    13501 gctcgtccct tcgaatctgc tgccggcaac gagcaattca tcgctgcgca ccagatgttt
    13561 cagataggcc ccggaggcgg cggcgaaagc gaggcccgcg gtgccggaga ccaccgatac
    13621 gaccagcagt tgtccgtagg tcagcgcgcc gaggacatac gcgaccggca cgctggccag
    13681 cgcgccgaac cggaccaggt ccatcgctat catcaccggc tgcttgttcc gatgctcgac
    13741 ccagggcccg agcccgaacg cgacgaccgc cgcgacggcg agcccggacg cctccagcag
    13801 cgcgacggcg aaggccgtgg agtccagtac ccgcaccgcg agcagtggaa aggcaccgaa
    13861 cgccagccag gtgccgtagg tgctgaccgc gtaggccgac cacagccaac cgaaatcgcg
    13921 tcccaaccgt gcgtgcatct cactccctcg acaaccggcc ctcgggtctg ggatcacagc
    13981 agccggggcc gcggcagatc aaacaaccgg tgcttcggcg agccacaacc agcagttgtg
    14041 tgcacctagg gtgggttcat ggataccgag gcggtccgat cgttcgtccg cgcggccgag
    14101 ctcggccaac tgcagcaggc ggccgacgaa ctcggcgtga cacagcaggc cgtgtccaag
    14161 cgcatcgccg cgctggagcg cgccctctgc gtccggttgt tcacccggac cgcacgcggc
    14221 gtcgagctga ccctcgacgg tcaggccttc ctcccgcacg cgcgcacgat catcacgagc
    14281 gtcgaccggg cggtggccgc gatcgaaccg ggatcgcgcg cactgcggat cgacgtgctc
    14341 ggcctgcgct cggcgcaagc cgttgtcctg cacgactatt ggcgcgcaca ccccgaaatc
    14401 gtcttggacg tcgtgaccct caaggtcgac gacccgcgcg tcgcggtggc cgccgtgcgg
    14461 gcgggtgaga tcgatgccac gttccgttcg gtcaccgatc ccgcgaccct gccggacgac
    14521 gtgcggatga tccacgcctt cgactcgcgg ctggaactgc ttgccggacc gcggcatccg
    14581 ctcgccgccg cacgtacgct gaccccggct cagttgcgca agcaccggat ctgggtgccg
    14641 ggcatcgcgg tgcgcagcga atgggcggac ttctacgatc agctcgccac gcacttcgat
    14701 ttgcgcatcg acgccgccgg gccgaatttc ggcaacgagg tactgctcga cattctggcg
    14761 gattcggcgg acgtggcgac cctcgtcggc gcgcgggacc ggtacctctg gcccgcgcac
    14821 tacgacctgc gccgcatccc gctcgcgaat ccggccctcg tctacccgct gtcgctcatc
    14881 gtggccgcgg cgaatccgca tccgggactg cgcggcgtcc tcgaccacgt cggcagtctg
    14941 cccccggtcc ccgcggatgc ctggcgcccg acctgggcag tgcggtgaca cgcggaaccg
    15001 caccgatgat ttccggtgcg cggcggcgtc tactcgaggg aacaccgacg agcaggaggc
    15061 gcaatgacca ctacccagga tccgcaacca tcggacatcc cggacagcag ggataccgcg
    15121 ctctaccggc tggaaccgtt ggtcggccgg tggcaggtgg aggcgtcgtt cgcgccgggc
    15181 ttcttcggcc cgggcacccc ggccgtcaag gaccgcagcg gcacgacgac gttcgaatgg
    15241 atgaagacca agcagttcct ggtcgagcac tcggtcatcg acaatccgat ggcgccggac
    15301 acgatcgtga tcatcggcct cgaccgggat ggcttgttcg tccggcatca ctacgattcg
    15361 cgtggtgtca gccgcaccta tcagatgagc ctggatggcg gtgtcctgca catgtggcgg
    15421 atggaacccg gcttctccca acgttattcg ggcacgttca gcgccgatgg gaaccagata
    15481 tccggtgcct gggagaagtc ggccgacggc gtcgagtggg agcacgactt cgatctgacg
    15541 tacttccgga tcgacgactg aagtgccgcg cgagatgcga aagaataatt gcgcaaattt
    15601 cctttcgtat ctagcctggg tggcatgccc gacgccgcgc cgccgaccat caccgatctc
    15661 gatgcgctga aggtcttcac gcatccgttg cggatagcgc tgtatcgcgc gctgaacacc
    15721 gccggttccg cgaccgcgtc gcagctggcc gaacaggtgg acgaggcggt ctcgctcgtg
    15781 agctaccacc tgcggaagct ggcggcgcac ggattcgtcg tggccgcacc ggaattgggg
    15841 accgacggcc gcgagcgctg gtggaaaccg gtgtcggaca agggctggag ctttcgcagc
    15901 tcggactttc tcgccgatcc cgagggcgcg atggtcgtcg gacaggtcac ccggcagctg
    15961 ctggccgacc gcagcgaacg gtaccgcgcc tacctcgacc agcagtcggc ctggccgaag
    16021 gcctggaccg acgcggcctt cagcgccgag tacacgccac ggctgacctc ggccgagctg
    16081 gccgagctgg aggctgagat caccgccgtg gtccgtcgct ggcaggaccg cggcgaggcg
    16141 gcggtcgcgg cgggcgaggc cgacggccgc gagcacgtcg cggtgcagct ctacggattt
    16201 ccgtcccggc cgtgagtacc ggagccgttc gggcggaagc ggcgccgccg gcgtatcggg
    16261 atgcgaacgt gctgcgctgg ctcggcgcgt tcgtctgctc gctgctgggg gacagcgtgt
    16321 attttctcgc gctgtcctgg gcggcgattc aagtcggcac gccggcgcag gccgggctgg
    16381 tactggcggt ggcggcggtg cccagggtgc tgctcatgct cggcggggga gtcatcgccg
    16441 accggttcgg gccgcgcaag gtgctgatcg gcagcgatct gacgcgctgc ctggtaatcc
    16501 tgggcgcggc gggtgtgctg gcggtgacga cacccggcgt ctggctgctc gccttggtcg
    16561 cgatggtgtt cggcgtgatc gatgcgctgt tcctgcccgc ggtcggcgcg ctgccgccgc
    16621 gcatcacgaa gccggaccag ttggcccggg tgcagggctt gcgcgggctg gcttcccgcg
    16681 ccgcgctcat cggcggctct ccgctcggcg gactggcact ggcggccggc gggccgtcgc
    16741 tcgcattcgt caccgccgca ctgttgttcg cggtgtcgct gccgctgctg atcgccgtcc
    16801 ggatcgcgcc gctgccggat gacggtgtgg ccgaacagca cagcaccgcg tgggcggatc
    16861 tggtcgaagg cgtgtgctac atccgccgcg accccgtgct ggcaccgctg gtcgtcgtcc
    16921 tcgccgtagg cgagctgggt ttcaccggtc cgctgaatat cggcgtcacc ctgctcgccg
    16981 atgaacgggg ctggggtgca acgggactcg gttggatcat cggcggattc ggcgtgggcg
    17041 cggccgccgc ttcactgttg ctcgcggtcg gcggccgggt accccgggcc ggactggtac
    17101 agccggtgtg cctggtgctc ggcgcggtcg cgatcggcgc gctggcctac gccccggcgc
    17161 tgccggcggc ggcgggtctc ggcatcgcca tcggactcac cgcgggactc agcggcgccc
    17221 tgtgtgcggc gctcgtccaa accaccaccg tcccagccta tctcggccgg gtgaccgcag
    17281 cggcgggcct ggtcaccctc ggcctcgcac ctctcatcta tccggtagtc ggcgcggcta
    17341 tcgcggcctg gggcacccgc cccgtcttcg tcgtcagcgc cgccatagtc gccctcggcg
    17401 cactcctagg cttccgtgcc acgtccctcc gccgcgccga actaccctga cccgcaacgc
    17461 gttctgcgta cacccgccgt tcgaccggtg acgcatacgc tccactgtcg cggaccgacc
    17521 ccgcactgtc gcgcattcgg ccggtgtggg cgctcgtgtc ccccctgcgc gggcatgatc
    17581 aggccggcgg tgcgtcggtt tccatgagtt cgagcaggcg ctcccgcacc ggggtgggcc
    17641 gggcgaagag gtaatcgtgg ccgccgggcc aggtttcgac cgtgcaggtg cgggtggtga
    17701 gtttcgacca ggccgtgagc gcgcccgcgg acatgaggtc gtggtcgccc agccacgcgg
    17761 tgatggggca gtccagcacc ggttcggtgg ggacgggtag ctccgcggac aacgccagat
    17821 ccgcatacca gcgccgggtc aggccctccc ggaactctgc gggcagcgcg tgccagtcgg
    17881 ccacgtccag gccgctgagc gcggccagct gggcgaggtc gatctggtcg atgcggccgc
    17941 tcgggaacac tcgggagaag cggctctcgc tggggtccgg ccggtaggag ctgacgatca
    18001 gccgtcgcac ctcgcggtgc ggggccagcc aggtcgcgat atgcgtgccg atcaggctgc
    18061 ccatgctgtg gccgagcacg tggtacggca cctccggcag cgcggccagc gcgtgcgtga
    18121 actgctcgtg aacgtcttcg agcgtccact cgggcggctc cgcgtagcgg tcctcccgcc
    18181 ccggcggctg caccagcagc aggtcgatat gcggtggcag ccattgtgtc caagtccaat
    18241 acgcaccggc ggcacccccg gccggcggta cgcagaccag gcaggcggtg cccggctggg
    18301 catcggacac cacatgctgc agccagggtg acggctgctt cactgttcgc tgacccattc
    18361 ccggttacct cagatcctgc gattggccgg cagcacgaac cgccggaaga cgagttcacg
    18421 aagcacgtcg tcgcctgctt cgacgatggt cacggcccgg gtatcgcgca ggtacttggc
    18481 gatgggcagc tcggtggtat agccgaggcc gccgaacatc tccgagccga ccgtggccac
    18541 ctgccagccg gtctgtccgc agaacatctt ggtggtcaag gccgatcgca gcgcgccgcg
    18601 ctggaggaat tccgcggccg ggtcggcggt cgccatgatg gcgtcgtatt cggttgccgc
    18661 ggccaggcat tggttgcgca tgacgtcgat ctgcatttcc atctgcccga gtttgcctgc
    18721 gaacacggcg ttctcgatga gggtgcgacc gcccagtcgt ttggtcatcg cgtaatccag
    18781 gcagagatcg cggatccgcc tggccacgcc gagcgcgatg gtcccgatca ggatccggct
    18841 cgagttcaag ccgacctcga tgatcttgag ccccggcccg ttcagcacat ggccgctcgg
    18901 cactacgcag tcggtgaacg acacctggta ggtgcccgcc gaccggagac cgatcatgtc
    18961 ccagcgtttg accacctgca cacccggtgt atcccgcggc acgagcaccg cgtggtaggt
    19021 ggcgcccttc ttgtccccgg cggacctggc gaacacgacg aggtagtcgg cgaagccgga
    19081 gttggtggag aacatcttct cgccgttgag caccacgtcg tcaccgcgcc tggtgagcgt
    19141 ggtggcgaga ttgatcagct cgctgccggc cgcctgctcg ctgcccagcg cggccgagta
    19201 gccgccctcg cgggtcatcg ccgtgaggaa tcgctctttg agctcgggtg acccgtacag
    19261 cgaaaccatc gagctgctga ggatggagat cagcagggtg aaggccgaac ccgcgtcggc
    19321 gtaggcgagt tcggagacga ggtcgatgct gtcggcgaga ccgagtccgg cgccgccgta
    19381 ttcggtgggc agccaccagt tcagcagtcc cattttgtgc aggggctcgt acagcgccag
    19441 aggcggttcc gcgcccgaat cgaagtcggc gtcgtggccg agcaacgtgg tccgcgcgaa
    19501 ctcgcggacg gcttgcaacg cttccgccgg tgccggcggc cggtcgtaga gaggcactga
    19561 tcagtccttt ccggtgacgg gcggcgggaa tgcgcgacgg aacgtaaagg cctcctgcgt
    19621 ggggcctttc gcgttcagca ggtccagcct ggccatgctt tcgccgacgt cgggcaggct
    19681 gccgacgggc agccaccaca gcaccgacgg agcaccgcgc ggcggcttga accatttccg
    19741 gcggatgcgc agggaaccgg cgtgttcgcc ccgataggtg aactcccgca gcgtcgccat
    19801 gtcctcccac accgaaatgt tcagcatgta ggggtcttcg gggagatcga acagcgactc
    19861 gagccggaag acgaaacccg gtgcggcgcg ggccatcgcg tcgatcttca aggcgagctc
    19921 gtggaaatcg gcgagcgtct cggacttcag cgagtcgacg gcgtagagga tgttcgcctg
    19981 cgcgagatgg tattcgccgc tcatcgtgtc gaagcctcct gtgcggcggg caggtggccc
    20041 gtctcgatga aatagtcgat ggtcgcggcc agtgacgcgg cactcgcggg tggaccggat
    20101 acgccgaccg acgtgagcgc cgcccgggtc gcggtggact cgaacgatga gcggccgtgg
    20161 tcgggttgct cgaaggcgat ctccgagaag gcttgcagca ccggatgagc ggcgttgtct
    20221 ggatcgccgg cgatcatgtc cgcccacagt cccgcgggga gttcggccag cgggtatccg
    20281 cgggcggcga gcgtggcgat gatcgatgcg aacggcaccg gttccgggct ggacaggtgg
    20341 aaggtcgcgc cggccgcctt gccgtcgcag gacagggcgg caatggcttt cgccgcgtag
    20401 ccgacgggga tgatgtcgcc ggtcagctcg gtcgcgggcg ctacgcccgc ctggatgcac
    20461 ccttggacga cgcgccagag cagatcggtc ggcggcaacc ggtagatcga gatgggtagc
    20521 ccgcgttcgc gggcgcgggc ggccatttcc tccgcgatcc acccggcctg cgcgtactcg
    20581 tccgtcagcg cggccgacgg gccggtcggc gcgtcctcgg ccggtgcggg cccggcggtg
    20641 tccggcggcc cgaagacggc gaacgtggac aggtgatgca ccgggaccgt ccggtggcgg
    20701 gcggccaggc gtaggacggc cgccatcccg tccaccgact cggattcgtc cacgactgcg
    20761 gcgcaatgga atacgccgtc cacggtgcgg gccagcgcat cgaactccct ctccgtcagg
    20821 ccgaaatggg gatcggtgag cctgccgggc accacgatca gtcggtcggc tatcgcgtcg
    20881 tcccacagcc ggtagccgcg catcgtgtcc cgcagctgag ccaggccctg cgccgcgttc
    20941 ggcgactcga cgaggcagtg cacggtcgac gacgtccggt ccagcagttc acggaccagg
    21001 aagctgccga cgaatccggt tgcgcccgtg acgaagagat gtgcggcggc ggccagggcg
    21061 accgggccgg aggttgcggc gggcacgata tcgtcgggca accccacctg gtccggcacc
    21121 ggttcttcga ccgcggtgga ttcgtcgtca ccggtcagga tcgtggcgat ccgcgcggcg
    21181 aggccggccg gcgtcggcgt ctggaagacg gcgttcgcgg acaggtgccc ggtcaatccg
    21241 agctgatgca ccaggcgatt tcgcagttcg agcgaggcga gcgaatcgaa accgagcgcc
    21301 atcagcggca gatcggcggc gacctcgtcg gccgaggcca gattggcgac ctcggcggcg
    21361 tgccgggtga tcatccggac cagttcttct cttcgctgga ccgcgggcaa accgatcagg
    21421 tggtcccgca gctgctcgcg ttcgcgtgcg gtgtcgtccg ccctgggtgc gctcgtggcc
    21481 tggcggggcc gaggcgcggc ccggaccatg tcgcgcagca ttgccggaac aagctgtgcg
    21541 tcaccagctc tggtcaactg gatgcggcag ggaatggcga gcggccggtc cgcggcgcgg
    21601 gccgcgtcga agagcgcgca gccgtccgcg gcgtcgagcg gaagcagtcc ccaccggccc
    21661 aggcgggcgt ggtccacctc ggacagaccc tcggtcatgc ccgcgtcgct cgcccacggc
    21721 ccccacgcca gcgagatgcc cggcaggccg tgcgcgcggc ggtgctgcac gagcgcgtcc
    21781 aggaaggcgt tgcctgccgc gtaattggcc tgccccggcg tgccgagcac acccgccacc
    21841 gaggagtagg tcaggaagcc ggacaactcg aggccctcgg tgagcagatg caaattcacc
    21901 gcgccgtcca ccttggcgcg catgacgcgc tcgatctggg cgtcggtgag cgtctcgacg
    21961 gtgccgtcgt cgagcacccc ggccgcgtgg atcaccgcgc cgagcggccg atcggcgggc
    22021 agcgagcgca gcagctcggc ggtggccgcg tagtcggcga tatcgcacgc cgccacccgg
    22081 acctcggcgc cgagtgcggt cagttcggcg acgagttcgg ctgcgccggg cgatgtttcg
    22141 ccgcgccggc tgaccaggag caggtgccgg acgtggtgcg cggtcgcgag gtggcgcgcg
    22201 aggagtccgc cgagtccgcc ggtgccgccg gtgatcagca ccgtgtggtc gggttccgcc
    22261 agcggtggcg cggtggcttc ggtgcgcagc gggccgatcc gcggggtact cagatgaccg
    22321 tcgcgaatcg cgagctgctc ctcggcggtg cgcagcgccg acggcaacgc ccgcgcggag
    22381 gcaggttcgt catcgagatc caccaggacg aatcggccgg ggtattcggc ctgtgcggtg
    22441 cggatcagtc cccagaccgc ggcgctcgcc agatcggtga cgtcctcgtc gggtgtgatg
    22501 gcgaccgcac gatgggtgat caccgcgagc cgtgccgccg ggtcgccggt ggccgcgagc
    22561 cacgcccgga tatcggacag cacctgccgc acgcggtcga gcgcggcacg ggccactccg
    22621 gcgggggtgg cgaccggggc gacgtcgagc aacaccggac ccgagctgtt cacggcggtg
    22681 gcatcggcgc agcgaccgaa ttcgattccg gcgtcggcga gttggcgggc gaggtcgtcg
    22741 ccgagcaccc acagctcgtc gccgggtccg gtatcggcgg gtgcggccag cgaggtccag
    22801 cggaccgtgg acagtgcctg ggtcgcgccc tgtagcagag acccggcggg ccggaagctc
    22861 agcgtcgcga tctggccgac ggcctcgccc gcgtcgtcgg cgagatcgac gcggaactcg
    22921 gtgtcgccca aaggcgtgat gcgggcccgg accgctgccg caccgagcgt atacaggccg
    22981 acccccgtcc aggtgaacgg caggaccgcc gcgtgcgtga gcgcgttccg gtcggccagg
    23041 gcggcgaggc agccgtgcag cacggcgtcg gtcaaggcag ggtgcagacc gtactgcccg
    23101 gcgtccatgg ctatttcgtc cggtagtcgc gattcgaggt agtactcggc accgctgcgc
    23161 cacaaccggt tcaggccgcg gaaggcgggc ccgtacgtca tacccgcctg tgccgcgcgg
    23221 tcgtagacgg cgtccacgtc catcggtgcg gcgccggtgg gtggccactc ggcgaatccg
    23281 tcggccggcg gctcccaggt gggggacacc gtgccgtgcg cgtgccgggt ccacgcgccg
    23341 aggcccccgc gccgggagta caggctgacc cgtcgtccgc ccgtgtcgtc caccgcaccg
    23401 acggtgagct ggacctggac cgtgtcgtcg ccgggcagca ccagcggagc ctcgagcacc
    23461 agctcgtcca cccattcggc gcccacctgt tcgcctgccc gcaaagcgag ttcgaccatc
    23521 gcggtgcccg gcaggatcac ctcgccgccg accgtgtggt ccgccagcca gggctggcgc
    23581 tccagcgaca ggctcgcggt gaacaggtgc ccctcggtgt cggcgagttg cacgcccgcg
    23641 ccgatcagcg ggtgggccgg ccgttcgagc cccgccgcgg tgaggtcggc cggtccggtg
    23701 cgcggcgcgt cggtgagcca gtagcgctgg cgctggaagg cataggtggg cagggggatt
    23761 cggcgcggtc gagtcggtgc gaaataggcg tcccagtcga cgggaacgcc gtacgcgtgc
    23821 gcctgggcga gggcggtggt catgcgatcg agaccgccgt cgtcgcggcg cagggtggcg
    23881 accacggccg cctccgcccg ggtcgcctcg acggtgcctt cgatgccgaa ggcgagcacc
    23941 ggatgcgggc tgatctcgat gaagacgtga tgtcctgcgg tcagcagctg acgggtggcg
    24001 gtctcgaatt cgaccggcct gcgcagattc tgccaccagt aggtcgcgtc gagcgcggtg
    24061 tgctcgatcg gcgcgccggt gaccgtggaa atcatcggca ccgatccggt gcgcggccgc
    24121 acccgggcga gcgcgtcgag cagctcgggt tcgagcgggt ccacgtgact gctgtgcgag
    24181 gcgtagtccg cgttgatggt ccgggtgtgc acgccggcgg ccgcgcattc ggcctgtagc
    24241 tccgcgatcg cgtccggttc gccgcagacc accgtcgact cgggcccgtt cgccgcggcg
    24301 accgacagcc gagtgccgaa ccgtgccata cgttcccgtg ccgcggccgc gcccaggccg
    24361 agcgagagca tcgcgccggt gcccgacagc ggcaggaccg ctcggctgcg tcgcgtcacg
    24421 atgagcgcgc cgtcgtccag ggacagcgcg cccgccacgc aggcggcggc gatctcgccc
    24481 tgggaatgtc ccaccaccgc agcgggttcg acgccatagg cctgccacac ccgtgccaat
    24541 gcgaccatca cggcccagag cactggctgc acgacatcga cccgatcgag actcggtgcg
    24601 cccgcgacat tgtcgaggac atcgtgcaac gaccacggga cgtatcgggc cagcgcgtca
    24661 ccgcattcgg ccaagctctg tgcgaacacc ggcgacgact tcaccagcgc cgctgccatt
    24721 tccggccact gaccgccctg cccggggaat acgaacaccg gacgcgggtc cggccaggcg
    24781 gtcccgcgca ccacttgcgg cgcggactcg tcgcgcgaga gcgccgtgag tccggtgagc
    24841 agttcgtctc ggtcggcgcc gaccaccacg gcccgatggt cgaaccgaga gcggttgagc
    24901 gccaaggaga atccgaggtc ctcgggacgt tcggtcgccg ctgcggtcag cagggccgcg
    24961 gcctgcgcgg acagggccgc ggcactgcgc gcggtgacca cccacggcgt cacctcggcc
    25021 ggtgggccac tcggctcggt ggcggccgtc gccaccggag cttcctcgag gatcacgtgt
    25081 gcgttcgtgc cgctgatacc gaacgaggac accccgcacc gccgtacccg ttcgccgcgt
    25141 ggccacggca ccgcttcggc gagtggccgg acacccgcct cagcccagtc cacatgccgg
    25201 gacggcgtcg tgaaatgcac cagcgcgggc aaggtttcgt ggcgcatcgc cagcaccatc
    25261 ttgatcaccc cggccacgcc ggcggccgcc tgcggatgac cgatgttcga cttcacgctg
    25321 ccgacccaca gcggccgctg cgccgggcgg ccggcaccgt aggcggcgat gagagcgccg
    25381 gcctcgatcg ggtcaccgag tgcggtgccc gtcccgtgcg cctccaccgc gtccacctcg
    25441 gcaggggaga ggtcgcaggc gtgcagtgcg tcgcggatga cccgttgctg ggagggcccg
    25501 ttgggcgcgg tcaggccgtt gctcgcgccg tcggagttga tcgccgagcc gcgcagcacc
    25561 gcgagtatct cgtgcccgtt cgcgcgggcg tcggacagtc gctccaggac gagcatgccg
    25621 acgccctcgc cccacccggc cccgtcggcg ttgtcggaga acggcttcga gcggccgtcc
    25681 ggcgccagcc cgccctgccg ggacatctcg gtgatcaccc gcgggtgaca catcaccgtc
    25741 gcgccgcccg ccagcgcgag cgagcattcg ccacgacgta gcgaagcggc ggccgcgtgc
    25801 agcgcgacca gcgacgacga gcacgccgtg tcgatggtga ccgcggggcc ctgcaaaccc
    25861 agcgtgtagg cgatccggcc ggacgcgacg ctgccgagtt cgccggtgag cagatatcct
    25921 tcggcgtcgt gcggcggtgc ctgcagcggc aggctgtagt cctggtagat cacgccggcg
    25981 aagacgccgg tgcgactgcc gaccagggcg gtcggatcga tggcggcgtg ttcgagggat
    26041 tcccaagcgc attcgagcag caggcgctgc tgcggattga tcgcggcggc ctcgcgcggt
    26101 gtgatcccga agaacccggc gtcgaaaagc gccgcgtccc gcaggaatcc gcctgcgcgc
    26161 acgtaggtcg tgccggggtg ctccggatcg gggtggtaga gggtgccggt gtcccagccg
    26221 cggtcggtgg ggaagggcgc gatcgcgtca ccgtcggcgg ccagcagctc ccagagttcc
    26281 tcgggcgagc gcacgccgcc gggaaagcgg cacgccatgc cgatgatcgc gatcggttcg
    26341 ctgatccgcg ctttcagccg ctcgttctcc ttcagcgact cgcgcagcgc ctcgaccagt
    26401 tcgtcgacgg atgtgttcac cgtgcctcct taccgagcgc gagccgcacc agctcggcgc
    26461 cgtccatgtc gtcgaatccg cgcggaccgc gggcggtggg cgcctgggcg tcgtcgcggt
    26521 ccgggttgtc gctcgggtcg tcgccgagtc cggcgaggtg gtcggcgagc gcccgcgggg
    26581 agggatagtc gtagatgagg gtggtcggca gccgtcgccc cagcgcgacg ctcagccggt
    26641 tgcgcaactc cacgctggtc atggactcga agccgagcgc tttgaacgac tggtcaacgc
    26701 tgacctcggc ggcggtgccc aggccgagca ccgcggcgat ctcgcgcacc accagatccc
    26761 ggatatcgcg tggggtggcg gacggcgcgg cgggctccgg accggtgacc gctaccggaa
    26821 cagcggcggt ggccggggct ccgggagcgt cgagccaata gcgccggcgc tggaacgcat
    26881 aggtgggcaa ggggattcgg cgcggccggg ccggcgcgaa atacgtgtgc cagtcgacgg
    26941 cgacgccgtg ggcgtcggct tgggccaggg acatggtcat gcggtcgaga ccgccgtcgt
    27001 cgcggcgcag cgtggcgagg accgcggcgt cggctccggt ggcctcgatc gtgccctcga
    27061 ggccgaaggc gaggaccggg tgggggctga tctcgatgaa gacgtggtgg cctgccgcga
    27121 gcagactacg ggtggcggcc tcgaactgga ccggtctgcg caggttgcgc caccagtatt
    27181 cggcgtcgag cgtttcgtgc cggatcggcg caccggtgac cgtcgaatac atcggcgccg
    27241 cccccgtgcg cggccgtacg gacgcgagcg cctcacggag ttcgcgctcg acggggtcga
    27301 cgtgactgct gtgcgaggcg tagtcggcat tgatcggcct ggcgcggatg tcatcggctt
    27361 cgcattcggc ttgtaactgc gcgatcgccg cgggctcccc gcacaccgcc accgatcccg
    27421 ggccgttgat cgcggcgatg tcgagccgag ttccgtaccg tgccatccgt tttcgggccg
    27481 cgtcggcccc gagcccgagc gagagcatcg cgccggtccc ggacagcggc agcaccacct
    27541 gactgcggcg cgcgaccacc cgggccccgt cgtcgaggga aagcgcaccc gcgacgcagg
    27601 cggcggcgat ctcgccctgc gaatgtccca ccaccgcagc gggttcgaca ccgtagccct
    27661 gccacacccg ggccagggcg accatcaccg cccatagcac gggttggacg acgtcgacgc
    27721 gctccaggct cggcgcgccc gcgacgccgt cgaggacatc cggcagcgac cagggcaggt
    27781 agggtcgcag cgccgccgcg cagtcggcca ggtgcccggc gaactccggc gacgatttcg
    27841 ccagtgcggt cgccattccc ggccactgcc cgccctgccc cggaaagacg aagaccggtc
    27901 gcgggtcggg ccaggccgtg ccccgcacca cctgcgccgc cggtacgccg cggcttaccg
    27961 cttcgaggcc cgacatcagc tccgcccggt cggtaccgac gatcactgcc cgatggtcga
    28021 agcgggaccg cgtgacggcc agcgagtacc cgatgtccgc gggccgctcg gtgtccgcgg
    28081 ctgtccgcaa tcgcgccgct tgcgcccgca ggcctgtctc gctgcgggcc gagatcaccc
    28141 acggcagcac gtccgccggg gcgggcgcgg cggggtcggc cgtctcgaat tccggtgcct
    28201 cctcgacgat cacgtgcgcg ttggtgccgg ccacgccgaa ggaggacacc ccgcaacgtc
    28261 gcgggcgttc accgcgtggc catggctcgg tctcggtgag tggcaggacc gcggccgccg
    28321 cccagtccac ctccggcgac ggcgtgccga aatgcaccag gccggggagc ttttcgtgct
    28381 gcaacgccag gaccgacttg atcagcccgg ccacacccgc ggcggcttgg gcatggccga
    28441 tattcgattt cacgctcccg acccgcaacg gccggtcccg tgcccgatcg acaccgtagg
    28501 tcgcgaccag ggccgttgct tcggctcggt cgccggctct ggtaccggag ccgtgggcct
    28561 cgacggcatc cacgtcggcg gccgatagtc cggcgtcggc cagcgtgcgc gtgatcaact
    28621 gttgctgtgc cgtggcgctc ggcgcggtga gaccggcgct cgcgccgtcg gaattgaccg
    28681 cggagccgcg gatcaccgcc agcacccggt gtccggtcgc ctgcgcgtcc gacagccgcg
    28741 ccagcatgat catgcccgcc ccttcggacc agaccgtgcc gtcggcgtcg gcggcgaacg
    28801 gcttggccct gccgtccggc gcgagcccct gctgcctggt gaattcggtg aagaatcccg
    28861 gcgtcggcat cacggagacg ccgccggcca gtgcgcggtc gcactcaccg gcgcgaagtg
    28921 cctgtaccgc aaggtgaatg gcgaccagtg aacccgaaga ggcggtatcg atcgtgatcg
    28981 cgggaccggt gaccccgagc gtgtaggcga tccggccgct gatcgcggcg gctatgttcc
    29041 cggtcagcat cagcccggcg gcgccatccg gtgccagatg cagcggcggg ccgtacgcgg
    29101 tggacagctg cgccgcgtac acgccggtat tcgtcgcgcg cagcgagtgc gggtcgacca
    29161 tggcgtgttc gcaagcctcc caagcgactt cgagcaggag tcgctgctcg ggatgcatcg
    29221 cggccgcctc gcggggggag atgccgaaga acgccgcgtc gaatgcggcg gcgtcgagga
    29281 agccgccgcg atgtaccgca ctggccccgg cgcgtgcggg atcggcgcgg agccggtcga
    29341 ggtcccagcc gcggtcggcc ggaaaatcgg tgacggccgt cgcaccggcg gacaagagat
    29401 cccagaatgc ttgcggcgaa acagaattgc cgggataccg gcaggccata ccgatgatgg
    29461 cgatcggttc cgctgccctt ttgtgtgtcg tgaacgcgga catgatcccc ctcgccgaag
    29521 acggccgcaa cggcggccga gtagatcgca gtgtcgaatt cgtcttgtcg gtgccgttac
    29581 ggcgtgatga tgactttcag ccccgtgcgg cgctgcgcgt cggcgaacgc ggcgggggcc
    29641 tcggtgagcg gaacccgcga cgatacgagc gggtcgagtt cgacgacgcc gcgcgccgcc
    29701 agatcgatcg cgcgcgggtg ggtctcgttg ctgcgccgca ccattgcgat ggtcagctct
    29761 ttaccgcggg cgagtgaggc ccggaacgtc gtggtgtccg agccggggat accgccgagc
    29821 accacccgcc cgcccggtcg cgtggccgcc atggcgatgt gcaccgcgtc gtcgtttccg
    29881 gccatttcga aggcgacatc gacgccgtgc gcggcgaagt cgggcgggtc cgcggcgggg
    29941 tagggatcga gaatctcgtc ggcgccccat ttcgcggcgg cgtctcgccg gtgtgccagc
    30001 ggctcgaccg cgagcacgcg ggataccccg gcggcgcgca gcacctggat cagcagcagt
    30061 ccgaccggcc cgcagcccac gaccgccgcg gtaccgccga acggtaccgg gccgagatcc
    30121 agcgcccaca gggcgaccgc cagcggctcg agcagggctc ctgcagcatc ggatacgttg
    30181 tccggcaacg gatgtaagcg atgcgtcggc cacggcagga tctcgcggag catcccgtcg
    30241 gtcacgccgt ggccggcgaa tcgcacgtga tagcaaagat ttcgataacc gtcgcggcag
    30301 gcgcggcagg cctcgcaagg gatcgccgga tcgatcgcga cccgttcgcc gcgccgcggt
    30361 ccggtgacga tctcacccgc gccctcgtgg ccgggtatca atggctcccc gagtttcgcg
    30421 tcgccgatcg cgccgtcttc gtaccagtgc agatccgatc cgcatatgcc gaccgcggtg
    30481 acccgtacca gggtctcgcc cgcagccgcc gccggcggtg gttcgttccc cacccgcagg
    30541 tccgcgattc catgaagtct cgctgtccgc attttcccga ctataggggg acattccgta
    30601 cggtgtccac gctccgagtg aaatgaagga agggtgaagg gtggatgaaa acagcaggta
    30661 ggcaacgtaa ttcgaggcac taccggtttg ccggaagtcg gatttgtcac ttctgttcgg
    30721 aaagaatgtg tcacctctga ttgggcctca ggacaattcg gacattcctg acctgggtcg
    30781 ctagatttcc gctcgcaaag ggtaagtgca tcaagtattt tgagcctcgg acaatgcgag
    30841 ccataagcgg aaggcagtgt gcccatgccc ggacagtccg cggccatcgt gccgttcgaa
    30901 gtcgagatcc cggaatccgt ggtgacggat gcgcgggagc gcctgcgccg caccagatgg
    30961 cccgagcccg agacggtcgg cgattggtcc cagggcacac ccgcggccta tctgcgcggg
    31021 ctgtgccggt actggctgga ggattacgac tggcgcgccg cccagcggcg gctgaatcgg
    31081 ttcccgcagt tccgcaccga gatcgacgga ctgccagtcc atttcgtgca cgcccggtcg
    31141 ccgcaccccg gcgcgatcgc gctactgatc acgcacggct ggcccggctc ggtcaccgaa
    31201 ttccagaagg tcgtcgcacc cctcaccgat ccggtctcgt tcggcggcaa cgcctccgac
    31261 gcgttccatg tcgtgtgccc gtcgctgccg gggttcggct tcagcggtaa gccggagcgg
    31321 accgggtggg gcgcggaacg gatcgccgac gcctgggacc agcttatgcg ccggctcggt
    31381 tacgcccgct acgccgccca gggcggcgac tggggtgcgc ggatcaccat ggcgctggcc
    31441 agacggcatc cgcagcaggt catcggcatc cacctgaaca tggtgccgtt ccgtgcgccg
    31501 gtgggtgccg aggacctcac cgaggcggac cgtcgcgccg tggccgcgct cgccggacat
    31561 cgcgcccagg gctcggcgta tgcagccatc caggcgactc gaccgcagag catcggctat
    31621 ggcctgacgg attcgcctgc ggcgctggcc ggttggatca tcgacaagtt cgaagcctgg
    31681 agcgattgcg gcggcgatcc cggcaccgtc ttcaccgaag acgagctgct cgacaacctc
    31741 ttgatgtatt ggctgcccgc caccggcgcc tcggccgcac ggctctactg ggaaagtttc
    31801 gccaccgcga ccggcgacga cagccgcatt acggtgccca ccgggtgttc ggtcttcccc
    31861 gccgacatct accggccgac gcgccgactg gccgagccgc agttcgccga tctgcggcac
    31921 tggaacgaac tcgaccgggg cgggcatttc gccgccctcg agcagcccgc cgtgttcgtc
    31981 gacgaggtca gggccacgtt ccgcgggctg cgctgagccg cgacggtcac cgaaccggtt
    32041 cgcgcccagc ggaattgtcg cgaaagcgca agccggcgat ggcggcggcc agtgcggcgg
    32101 cggccatcgc cagccaggcg atgcggaagt cgcgtaacgc ttggtggccg aggagcacgg
    32161 tgaggatcgc gacgccgagc gcggaggaga gctgccgcga catcatgagc accgcgctgg
    32221 ccagcgaggt ctgttccgac ggcagggtgg ccgccgaccc gaacagcgca ggctgcaaca
    32281 gcgcggtgct gatgccggcg agcacggcgc cgggcaggaa cacgacgaga tactgcggcc
    32341 ggtccgtcgc ggtgagcgcc caccagccgc agccggccgc gagcgccagg ccaccgagca
    32401 tggtcgcgat ccgcgcgccg acccgagcca cgatccggcc gtacagcagt gccgtcgtca
    32461 tggtgctcag cggcatgggc gctatgctga gcgccgcggt cacgacggaa tagtgccagc
    32521 gaccggtgag gaacagcgtg gccgccagga tcatcgcggc gaaggccagg tagtacagga
    32581 acaatccgcc gaccgcgacc gtgaacagcc ggtgccggaa gagttcgaag ctgaccaccg
    32641 ggtcgggcgc tcggcgcaga tgacgcacgg tcagcgccgc gagtagcacg gtcgccagcg
    32701 cgcagccgag gatcgccttg gagccgtagc cccactcggg ggcctgcacg aagacggtcg
    32761 tcagcccggc cgcggtacag agcaccaacg tggcgccgag cagatccagg cgtttgcggg
    32821 tgccgcgcgc cgcggcgggc agcacccggc gcccggccag caccgcgacc acgacgaccg
    32881 gaatgttgat caggaagatc caccgccagc cggcggccag cagcagaccc cctgccaccg
    32941 ggccgctgcc ggcgccggcc gcggcgacgg cggtccagat gcccatcacc ttggcgtgtt
    33001 cgcgcggcgg gaaggcaggc agggcgaggc cgagcgaggt cgggatcagg atcgcgcccg
    33061 cgacggcctg caccacccgc gcggcgacca gcacgccgag cgtcggggcg agggcacaac
    33121 ccagcgacgc caccccgaac aacgtcatac ccacgaggaa cgcggccttg cggccgatgt
    33181 cgtctgccat ccgccccgcg ggcaccagca tggccgcgag cacgatggtg tacgcgttga
    33241 gcacccacga cacctgagcc agcgtgctgc cgtggaacgt ttgctccagt gcggggaagg
    33301 cgacattgac cgcgaacagg tcgaggatgg cgaggaattg ggcggccgag gcgaccgcca
    33361 gaatccgcca ccgccggctg tcgaccggca ggacggcagg gttgtccggg atgtgggctg
    33421 tcacgtcacg tcaccgtaca gagccgtcgc ggcggccacg agtgccgtgc ttgccatcat
    33481 tcgatagctt tgtgacatgc ccagtgtccc aggcactctc gcggtgctgc tgctgtcgca
    33541 gcaggccgcc atcgaggtcg cgctcgcgtg tcaggccttc ggtacgcccc cacacgacca
    33601 cgtgggcgac tggtacgacc tgcggttgtg cggcgtcgac ggtgcgggtg cgcacgtcgg
    33661 cctgcgggcc tggttcggtc acgctgggcc cgccggttcg ttcggcatgt gcgccaccca
    33721 cggcctcgac gacctggcga ccgcggatac ggtgctcgtc cccggaaccg gtgacgtgcg
    33781 tacggatccg cctgcggcgg cgctggccgc gatccgcgcc gcgcgggcgc gcggcgccag
    33841 gatggtctcg ctgtgctccg gcgcgttcgt gctggccgcg gccggggtgc tcgacggcag
    33901 aaccgccacc agtcactggg aacacgccgc cctgctggcg agccgtttcc cggccgtgcg
    33961 ggtggacccg aacattctct acaccgacga acccgacgtg ctcaccagtg ccggactcat
    34021 ggccgggatc gacctgtgcc tgcacgtcat tcgcgcggac ctgggctccc gcgccgccaa
    34081 cgcggtagcg cgccggatga tcgtcccgcc gcatcgtgcg ggcggtcagg cgcagtacct
    34141 ggaatcacct gtgcccgccc cgcgcggtgg ctccggcctc ggcgaggtgc tggagtgggc
    34201 gatggcacga ctcgatcagc cgaccggtgt gggcgacctc gcggccgagg caggcgtgtc
    34261 cgtgcggacg ctgatccgcc ggtttcatgc cgaactcggc accacgccga gccgctggct
    34321 gctggtgcag cgcctcgccc gcgcgcgcga actgctcgaa cacaccggcc tgccggtcga
    34381 tctcgtcgcc gcgcacagcg gcctgggcac cgcgcccaac ctgcgcgccc acttcgcccg
    34441 cgaactcggt ctgtcgccga cgaagtatcg acgcgactac caccccggcc agtagtgcgc
    34501 tgttctattg tgctggagca ttattcgggg cgcgccgccg cggccgccct ggcggcgtgc
    34561 gggagcgcgt cgaggatcgt ggtgagcgcg cgatcgtcgt gcgcggccgt gacgaaccag
    34621 gcctcgtaga cactcggcgg tagcgccaca ccgtgttcca gcatggtgtg gaagaacggc
    34681 gggaaccgga aggtgtcctg cgcctgcaca gccgcgtagt cgcgggccgg ggtgggggag
    34741 aacagcaccg agaacaggtt gcccgcggac tgaatggtat gtgcgacacc ggcttcggtg
    34801 agggcagcgg tggtggcggt ctgaatcgtg ctgctggttt cgtccagcag gtcgtaggtc
    34861 ttctggtccg cgagccgcag cgtggccagg cccgcggcga cggcgagcgg gttcccggac
    34921 agcgtgcccg cctgatacac gggcccgtcc ggcgcgagac acgccatcac gtcgtggcgg
    34981 ccaccgaccg ccgccagcgg catgccgccc ccgatcacct tgccgaacgc gaccaggtcg
    35041 gcgtcgtaag gtgcggtcga acgcgacctt tcgaggcccc agtagccgtc cggcgcgacc
    35101 cggaacccgg tgagcacctc gtccaggatc agcagcgcgt cgtgttcgtg cacgacggcg
    35161 gccagcgcgg cgttgaatcc gtcgccgggc gcgacgacac ccatgttcgc ggcggcggct
    35221 tcgacgatga cggccgcgat ctgtcccggg tgcgccgcga aagcggcgtg caccgcggcg
    35281 atgtcgttgt acggcagcac gatcgtctgc gcggcgatcg gctcgggcac cccggccgac
    35341 gcgggcaggc cgaaggtggc cacgccggag cccgccgcgg cgagcaggcc gtccgaatga
    35401 ccgtgatagt ggccggcgaa cttgaccacc aacggctttc cggtgaaccc gcgggccagc
    35461 cgaatcgcgg tcatcgtcgc ctcggtgccg gtggacacga gccgcagctc gtcgatcagc
    35521 ccgcccccgg cgcgggggcc gccgagccgg gcgacgacga gttcggccag ctcggtctcg
    35581 gccggcgtgc tggcgccgaa cgacaacccg cgcgccgccg cgtcctgcac ggccgcaacg
    35641 acttccggat gcgcatggcc gagaatggcg ggcccccaag acgctacgag atcgacgtac
    35701 tcgcgtcccg tcacgtcggt gacatacggc cccgccgcac tcactatgaa ccggggcgcg
    35761 cccccgaccg accgaaaagc gcgcaccggc gagttcaccc cgcccggaat aacctgccgc
    35821 gcacgatcga actgaatttc gttgctcgta gaagcagcca tacccctcag cctaggggag
    35881 ccgccgagtc ggcggccgcg gcgcggcggc gcaggaccat ggggaggccg tcgcgagggc
    35941 gcagcgtcag ggtgtgttcg gggaggaccc gggcgcccgc ggcgaggtcg aaggtgtagc
    36001 gctgggtgag catggcgagg atgagtttgg cctggatgcg ggcgaaaccc aggccgatgc
    36061 actggcggtg acccgcgccg aagggaagat aggaaaagcg tgggcggaca agaggattcg
    36121 cggtggcgtc ggccgcgggg aagacgaact gccggtgctc gggcaggaat cggcgcggat
    36181 cgaaaccttc gggattgggc caggatcgcg gatcgtggtg caggagatac ggtgccacgt
    36241 acacggtcgc gcccgccggc acgtggtagc cgccgagcac gtcgtcggcg atggcttgcc
    36301 gttcgatcag ccaggaaggc ggatacagcc gcatcgcctc ctcgatgacg gccgaggtcc
    36361 acggcagctg gtcgaggtcg gcgggcgtag gacggcggcc gccgagcacg gtgtcgacct
    36421 cggcgatcag gcgctcgcgc gcctcgggat gattcgacag cagcagcagg gtccaggcca
    36481 gcgaataggc cgtggtgtcg tgcccgacca gcagaaaggt cttcagttcg tcgcggacct
    36541 gccgcgggct catcgccgcc gcccccgcct cgtcccgcgc gtcgagcagc agaccgagca
    36601 gatcgtgccg ctcgtcgcga cggtcgtcct gtcgttcccg gatcagccgg gcgaccacgt
    36661 cgtccagcac cccgaccgcc gcgtccagct tgcgccagcg cggtgcctgc aaccgcaacg
    36721 ccgaatcggg ggtgatgccc gggatacgca gcggcagcca ggtcagcagc gaggtcatcg
    36781 ccttgccgac gcagcgcagg atctcgacga gcgcctcgtg cacccgggcc gcgtcatcgg
    36841 acaggtcgcc accgaacagc gcggggccgg tgacgtcgag cgtcaacgcg ttcatcgcga
    36901 cggagacatc gagccggtcg ccgtcgggac gggtcgccca gcgggccagg gcacgttccg
    36961 cggcgtcgat catggactcg gcgaaccggt ccagctgcct gcgggcgaac agcggctgca
    37021 tgatccggcg ctgcctggtc caggactcgc cctcgttggt cagcagtccg ttgcccaggg
    37081 ccatcgccgc gaccttggca ttgagggtct tgccgtagtt gctctgccgc gcgacgaaga
    37141 cggcttcgac gagatcgggg tcgttcacga ggaagaactg ctgccccgag gcgtctattc
    37201 ggacgatgtt gccgtaacgc tcgacgagtt cctggaatgc ggagcatgga tctcggcgga
    37261 ttctggtcat tacccggaat gcgtccaggc ccgtcggtcc gggcgctcgg gccggctcgg
    37321 ccgcggtatc gatgagcggt ggggcttcgg tcacggtcgt cgcttcccgt aatgcttttg
    37381 gggagatttg aatcggtgtt gttcgtccaa gatcaggggt gttcgcccga atttcaaccc
    37441 cccatccggg gcatcccgga ccacgagttc ctctgccaga ctggcctgat gggcgacaac
    37501 gactgtcgaa gcctgccttt cggaacaggt cgcgcacccg catgggctgc gcagtgagac
    37561 ggtccgtggg gagtgagagg atccagatgg aagcggtaga gcaattcctg aaagagaatt
    37621 cgatcacgat ggtcgaactc gccacccccg atatgaccgg cgcccttcgc ggaaagagaa
    37681 tcccggtcga atcctttctg gccaacggaa tgtcggacgg ggtcggtctt tcctcggcgg
    37741 ttttggcctg ggattaccgg atggaggtca tcgagaccgc cgactacagc tggtcgaacg
    37801 gatatcccga tatcttcctg cggcccgacg tggcgacctt gcggctggtg ccgtggaagc
    37861 cgaagacggc gctggtcttc tgtgacgtgg tggacgcagc aggcgaactg gccgcgatcg
    37921 cgccgcgcga ggtcctgcgc tgcgtggtcg ccgatgtcga aaacgccggg ctcgcaccgt
    37981 atatcgcgat ggagaccgag ttctacgcgc tcgacggcga gtcgctgcgc gcgcggggag
    38041 atcgcaaccc ggtctacagc ctgcacgaca accattacct ggagccgttt ctcgacgaga
    38101 tctgcgccat gctgctgagc gccgacgtcg aggtcgaggc gtgcggcgcc gagtacgcgc
    38161 ccggtcaggt cgagatcaac ctgaccccct ccgatcccgt caccgcggcc gacagcctgc
    38221 tgttcttccg ttatgcggtc aagcagctcg caccgcggca cgggtatcgc gccacgttca
    38281 tggcgaagcc gttcggcgat ctgtccggca gcgggttgca catccatcag agcatgtggg
    38341 ggcaagacaa gagcaacgcg ttctgggatg cgcggaccgg cggattgagt gcggtcggcg
    38401 gcaattatgt tgcgggactg ctgaagtacg cggcggagct gcaactcgtc gcggtgccga
    38461 cgcccaacgg ctacaagcgg gtgacggacc attcgttcgc gccgacgaac ctgtcctggg
    38521 gtttggacaa tcggtgcgcc gccgtgcggg tgctgatccg ggatgccaag ggcacccggg
    38581 tggaaacgcg gatcgccgcc gccgacgcca atccctatct actcgccgca gcccagctcg
    38641 cggcgggctc ggccggcgtc accgaagggc tgacgccggc cgagcccgcc gcgaactcct
    38701 atgtgtcgga agaatattcg ccgctgccga caaacatttg ggcggcggca acgcttttcg
    38761 gcgagagcga attcgcccgg cgggccctcg gcacggggac cgtgcagaac ctgtaccagg
    38821 tggcgcgcag cgaggccgcg gcgggccagc gagaagtgac cgaatgggag cgcgcgcggt
    38881 atctggattc ggtgtaggcg aggtcgctcc gaccttttcg atcgtcagga agtaggagat
    38941 acccgtgtgt ggtgtggtcg gattcatcga cagcggatta cggaaagacc agcggctgga
    39001 cctggtgcgt cgcgggatcc gggcgatcgc gcatcgcggt ccggacgaag taggcctcta
    39061 cgacagcgcc gatttcaccc tcggcaccgt ccggctctcg gtcatcgacc cgaggctcgg
    39121 ccagcaaccc atggtcacgc cggatcagcg gtacatcgcc ggattcaacg gcgaggtgtt
    39181 caactatctc gaactgcgca gcgaactgga gggctacggc gttcgtttcc ggacgaactc
    39241 cgataccgag gtgctgctgc attccttcgc ctactggggc ctcgacgcgc tgtcccgatt
    39301 gaacggccaa tacggtttcg tgttctacga caagtgggaa cggaccctga tcctgggccg
    39361 ggaccgcttc ggtgagcggc cgatgttcta caccgagcaa gacggcacgc tctatttcgc
    39421 gtccgagatc aagggactgt tcgcgtttcc gcgggtgccg cgcgagctgg ccgcggacaa
    39481 ggtgcggcgc gcgatgcggt attggagccc ggtcccgggg gagacctgct tcaccggcat
    39541 cgacgcgatc ccgccgggac acatcctcac cgtccgggac gggcaggcgg agctgtcgaa
    39601 gtattaccac ggcatcgcgc gccaggatgc cgtcgcgccg ccgaagtcct tcgaggaggc
    39661 caagagcggg ctgcgggagg tgatccggga ctcggtgcgg ctgcggctgc gcggcgacta
    39721 tccgctgggc acctacatca gcggcggcat cgactcggcc gtcatctcct cggtgatgag
    39781 cgagctgatc ggggagccgc tcaccacgtt ctccatcgac gcagcggaca gtccggtgga
    39841 cgagtcgccg taccagcagg ccatggtgga ccggctgggc agcaggcaca cccggatacc
    39901 ggtatcgcgt gcgcaggtcc gggaacggtt cccgcatgtc gtgcggcagt gcgagcaacc
    39961 gttgcatttc accgcgccgg tggcctacgg cgtgatggcc gagcacgtgg ggctggccgg
    40021 ggtgcgcatc atcctcggcg gcgagggcgc cgacgaactg ttcgccggct acgacgtggc
    40081 caaagaggcg acgatcctcg aacggtgttt gcgcggtggg tctttcgcgg gcgcggcgga
    40141 ggaactggag ctggcgctga acgatatgcg ctacagcgat gccaccaatg ccgccgcgat
    40201 cctgcgcttc tacgccgacc gcgcggaccg tgacttcacc ctcggcgccc acctgcggcg
    40261 cttcgaaacc gagccggtcg accagctcat cgccgcgacc ggcgacgtct acgacgacca
    40321 cgcggtgctg ctgcgccggt tgcggaccga gttccccgat ttcgaccggc ggcccgcgat
    40381 cgaccgatcg atgctcgtcg acatgcacac gttcctgatc ggctacggga tgacgtgcct
    40441 gggtgaccga gccggcacgg gttacggcgt cgaaggccgc tacccgttca tggactcgca
    40501 cgtagtgcag tacgcggcag cgttgccggt cgactggaag ctgaacggcg cgcgggcgaa
    40561 acatattctg cgcgaggcct attccgatcg gctgccgcac ggcatcgtca accggccgaa
    40621 gttcgggatg cgactgcccg gcgccgaggc gctgctgccc gacggcgacg actgggtcgc
    40681 cgcggtgctg agcccgtcca cgatcaagcg ggtcgggttc ctggtgcccg aggcggtgga
    40741 ccggctcgtc gaccgggtga ccggatcgcg gtcgccccgg gtgccgtatc cgttcggcga
    40801 cgcctatgtg cacctgctca gcgtgctgct gatggaggag ttcctgatcc acgacttcca
    40861 ggtgcccgag gtcgacatcg accgcatcat gatgcgcgac atcgacgggg accacgaccc
    40921 ggtgggcacg gccgcgcgct gacgccagcc aagagaggat ccatcatgtc ccacgtcgac
    40981 ctggtcgacg atgtgcgaga ggtcgggacg gcggtcctgg aagcccttgt cgcgcatgtc
    41041 gaatccgtcc gggccggttc gggtgaggtc gtctcggcgg ccgatatcga tacggtgtcc
    41101 aagcggctgg agctgcgccg gtgggtggag gaagggggca tgaccctgcc cgaactgctc
    41161 tccttcgtca ccacctacag cgatatctcg gccagccatc accatccggg atacatgggc
    41221 catcagatcg cgccctcgga tacccccggt gtggtcgccg acctgctgca agcggtgacc
    41281 aacaacattc ccctggtcta cgagctggca ccggccgccg cggcggtgga ccgggcggtg
    41341 tgccgctgga tgctcgacca cgtcggctgg ggcgagaccg gcctcggcgc catcaccaac
    41401 ggcggcacgc tgggcaatct gaccgcgctg ctcgcggcgc gctcgcacgc cgatacgacc
    41461 gcgtggcagc ggggaacgcc gggcgatctg gtcatcctgg cgcccgccac gagtcactac
    41521 tcggtgcgaa aagcggctgc cgtcatgggg ttaggggtga acggcgtcta cccgctgcgc
    41581 accgacgcgc tcggccgcat cgatccggcg gggctggccc ctgcgctggc cgacgtgcgg
    41641 gcccagggcc tgcggccggt cgccgtggtg gccaacggct gtgccaccgg gacgggcctg
    41701 tacgacccga tcgccgaggt ggcacagttc tgcgacgcca acggactgtg gctgcacatg
    41761 gacggcgcgc acggtgcggc cgcgctgctc tcgccgcggc tgcgcggtct gctcgccggc
    41821 ctcgaacgcg cggactccac ggtatgggac gggcacaaga tgctgcgcac ctcggctctc
    41881 tgcacgggtg tgctgttccg cgaaaagcgt tatctcgaca cgatgttcaa gcaggatgcg
    41941 agctacctgt accggcccga agccgaagac gtcgatcccg gccagtacac cttcgagaca
    42001 tccaaggcac cgctcggtct gaaggtcttg ctgaccctcg cctatcgcgg cgaagcatcg
    42061 ttgcgctcct atgtcgagcg gcagtacggt ctggccaccg agctgtggga gctcatccag
    42121 gaacgtcccg atttcaccgc gccgtatcag ccgcagagca acatcctctg cttccgctac
    42181 gaaccgtgcg gcgaccggca gctcgaactg cgggcgcggc tgatccagga cggccggttc
    42241 tacctgtcgt ccttccggct gggcggtcgc ccgtacctgc gggcgtcgct catgtcgccg
    42301 accaccgacc gagagacgct gcaccagctc ctggaggtga tcacgaaggt cgccgccgtg
    42361 tgatgttccg ctgtgggaca tggcatctcg tgctcccggt ctggccgaag tggctgtgcc
    42421 cgccgccggg ttggcggaca ctgtagacag gtcgttctcg tacgggaggg agacacgtca
    42481 tgggtgagca gggcgcggcc gtggtcgcga cggcgccgca tcggttgccg gtgctggggc
    42541 acctgctgtc gctgctgcgg gatccgctgg gcttcatggc gtcgctgccc gcgcacggtg
    42601 acctggtccg gatcggtctc gggccggtca ccgccgtggt ggtctgcgac cccgacctga
    42661 cccagcagat gctgcggcag gaccgcatct tcgacaaggg cggcccgcag ttcgaccgcg
    42721 gccgggaact ggtcggccac ggcctggcca cctgtccgta cgcgatgcac cggcggcaac
    42781 ggcggctgtt gcagcccgcc ttccacgccg atcggatcac cgggtacgcg ccgatgatga
    42841 cctaccagat caccgagatg gtcgattcct ggcgcgacgg cgaggtgatc gacgtcaaag
    42901 cgcaactgca caccctcgcg gccaaggtga ccgcggcgac gctgttcggg caggcgatgc
    42961 cggaatccga ccagcagcgg ctgttgcgcg atgtggaggt ggtcttcgcc ggcgtgatcc
    43021 ggcaggcgat gatgccggaa tgggtgcgcc gctggccggt cctgggcaac cgcgcctgcc
    43081 tgcgggctgc cgaggaggcg cgcgccatcc tcggtgagct ggtcgccgcc cggcgcgccg
    43141 agggcgtcga ccacggcgat ctctgctcgg ccctggtcat ggcccgcgac aacgacggcg
    43201 ggcagttgag cgacggcgag atcgtcgatc aggtgctcac cttcttcttc gcgggcaccg
    43261 acaccaccgc gacggcgctg gcgtgggcgt tgatccagct cgaccggcat ccggaggtcg
    43321 ccgcccggct gcacgccgag gtcgatgccg tcctggcggg ggccgccgcg cggcacgggg
    43381 atctgccgcg cctgccgttc accggtcagg tcatcgccga aaccctgcgc ttgcgtccgc
    43441 cggcctggtt gtcgacccgc acggtgaccg aggacaccga gctcggcggt cacccgctgc
    43501 ccgcgggcag cacggtgatc ttcagttcgt acctgatcca gcaccgcccc gacctctatc
    43561 ccgacccgga acgtttcgat cccgaccgtt tcgacccggc tcggcccgag ccgccgcgcg
    43621 acgcgcagct ggccttcgcg gcgggcgcgc gcaaatgcat cggggaccgg tacgcgctga
    43681 ccgaggccac cctggcactg gccaccatcg ccacccgctg gcggttgcgc agcctgcgcg
    43741 gtaccgatat ccggccgacg ctcgccgtgg tgcccgaacc gcggcgactg cggatgcggg
    43801 ccaccgcccg cacgccgcgc agcgcgcggg ccgaggaacc ggggcaactg gtctgagggt
    43861 ttgagaacca ctgtgtcagt ggctgattcg cagaatacga ggcgtcagcg gaacaggcgc
    43921 ggtagatact ggaccatgag ggtggaccac gtgaggtggg tgagcatcgg tgcctggacg
    43981 ccgccggtgg cgcggcgttg cagaccgaac agcgtgccca tgaggaccga ggccagcacc
    44041 agggccggat tgcgggtggc ggcggtggtg caggcgtaga cgccggtgga ggcgaggacc
    44101 ggatgtcgtc ccgccacggc gtagacggca ccgcggaaga agatctcctc ggcggcgccg
    44161 ttggccagtg tgatcagcag cacccgcggg gtgggtcccc gttcggcgta gcgcagcacg
    44221 ccggtgatcg ccttgcgcag gaaggggatt cgccgggcga tcaatccgca gccgtagaag
    44281 acggcgaacg tggccgcacc gagcgcgatg ggggcgagca cgggcgcggg ccgctcgccg
    44341 tcgggtgggg tgcgaccgcc cagcgtccag gtcgccgcgg tggcgagggt gagccggtag
    44401 aaccgcgcgg aatcgggctc ggcggcgaac gaggcgccga gcaggccggt gcccgcgagg
    44461 gcgacgaccg ccacccggcg gcggcgtgcg agcagaccgg cggaactcat gcggcgcgtg
    44521 ccgctttcgc gcgttccccg agcgcacgca ggacggcggc gtcgtagtcg agtgggtcga
    44581 acggcaccag ttcgcgaatg ctgttgtccc gcaccaccac ctcgttggtc atcgagtcga
    44641 ccagggcgcg accggtggtg gtgtcgacat cggtcaccag tgacagccac agcgaggaca
    44701 tccgcggcga gagcagcggc accggcagca cgagcagcgg gcggccttcg atctcggcga
    44761 cccggcggag catgtcgaga tattcgagga cgtcggggcc gccgatctcg aaggtgcgtc
    44821 cggtggtttc ggggttgtcc aacaccccga ccaggtagcg caccacgtcg tcgacggcga
    44881 tcggctgcgt tcgggtgcgt acccagcgcg gcgtgaccat cgcgggcagg tgttcgacca
    44941 gctgccgggt gatctcccag gagatgccgc cgtgtccgac aatgattccc gcgcgcagcg
    45001 tggtcaccgg cacgcccgcg gcgccgagca gtccctcgac ctcccggcgg ctgcgcaggt
    45061 gcgcggacag gtcgtcggta tcgtcgccga ggccgccgag atagatgatc cggcgcaccc
    45121 cggcgtcggc cgcggcacgg ccgaagttgc gtgcggccgc ggcatcgcgg cgtcggaagt
    45181 ccgcttcggc cagcgagtgg accaggtagt acgcggcgtc gcagtcgcgc agcgccgcgc
    45241 gcagcgaatc ggggtcgccg acatcggcgc cgatcggtgt gccgctgccg cgataggact
    45301 ccgggtgccg ggtcatggcg cggaccggcc gtccggtcgc cgccagttcc gggcacagtc
    45361 gctgcccgac gaagccggtc gatccggcga cgagcacggt catgggcgca tcctctccgt
    45421 cgcggtgggt ggtgccgggg tggtgagcct ttctccgcca ggctactcga gcccgcgacg
    45481 cccgctggtc gacccgcagc cgaccggggc gcgcccctgc cgaggtgccg gacccgccgg
    45541 cggtggccat gtcgaggacc ttcgtcgccg gacgaccagc acgacaacgc ccgccaccga
    45601 tcgtattcgg tagcgggcga gcgggtttcg ttgttcagtg cagggcgagg cggcggtact
    45661 cgagtgcggt ggccaccgcg taaccgccgc cgccggcgat cgcgaggatg gcgaagaagc
    45721 cgggcatgcc gacgaagagc gcggcggtcg agaccagggc gagccaggca ccgaggccgt
    45781 agtgcaggac gttgcggcgt gcggcgccct caccgaggta cagcaggccg acgacgagtc
    45841 cggaaccggc cggccacagg accgactgca gctcgggcag gcccgcggtg gcggtgagtc
    45901 cggtgatggc cacgaacagg gccccgaagc ccaccgccca ggacagtccg aggagttgtc
    45961 cggtccgcac gtcgggttcg gcggcgccac gctgagcgcg cagcgcggca cgggtggcgc
    46021 tgaccgtgcc gaccgcgaaa cccatgccca acagtgcgag cggcagccat gcgggcagtg
    46081 ccagcagcgg atcggcgccc cgggacagcg cggcggcacc gtgtcccagg atgtaggcga
    46141 gtccgaaact gacgtaggtg gaacgattgt cgacgtcgcc gctgcgggag cgcacgggcg
    46201 cgggggcgag cggggcggcg agttgtgcgg tggtcatgac aggagcctcc gagataacgg
    46261 tgtgggtggg ggtacgagag cggtgcgatg gtctgcggcg tcagcggtgc gcgtccggca
    46321 cgatgacgac tttgcctgcg acggtgtgtg attcggcgag ggtcagggcc gcggccgcct
    46381 cggaaagcgg gaactccgcg gcgatctgcg gggtcagcgc gccctcggcc agcaggcgga
    46441 acacctgggt gaggtcctcg cgcagttgcc tgcggaagat gtcgaggcgg cgctgacccg
    46501 cccagaggtt gtagaagcgc gcgctcttgc cgttgggcaa caggttccac agcagcagtc
    46561 gcggaaacag tttcagcacg ggcagtttcg ggttgccgtc cgcgttcttc gtcgccgcgg
    46621 tgccgtagga gacgagcgtg ccgccgcggc gcagcagccg ccacgaatcg accacggtgg
    46681 ccccgccgac gtgatcgaac accgcgtcga cgccgtccgg cgcgacctcc cggatccggg
    46741 cgtacatgtc cgggtcgcgg tagtcgaccg gagtcacgcc ttgctcgcgc agcgcggcgt
    46801 ggtggcgcgg ggcggcggtg ccgatcacgg tgatcccggc ctgccgggcc agctgcacga
    46861 gcgtggagcc gacaccgccg ttcgcgccga gcacgacaat cgttgcgccg gtgcggaccc
    46921 gggccgtccg gtgcaacagt tgccaggccg tcagtccgtt gacgaccacc gtctcggcgg
    46981 cggccggggt caccccgtcc ggcacgggga ccagatccgc ggcgtccagc acgagggcgc
    47041 tggaccaggc gccgaccttg gtgacggcgg cgaagcggca gccgatcaat ccggtgtcga
    47101 cgcccggtcc ggtcgcggtg accgtgccga ccacgtcgta gcccggcacg aaggggaacg
    47161 acggttggtc gaagtacttg ccgcggcgca tctgctgttc ggcgaacgag acgccggtcg
    47221 cctccatgcc caggacgacc tgaccggcgg cgggtgtcgg caggtcgcgg gtggtgacct
    47281 gcaggccgtc gggctcgacc ctgtccggca ggacgatcgc cgtgatggtg gcggtgctgt
    47341 tgttcatggt gtgtccgatc cgatccggtt gagctaacgg atgtaaggct acggctgtta
    47401 ggtgaggttg cgcaagggtt aacagctgta agtttttgtc tgtaaggttt tggtcatgaa
    47461 cgaggccaac agggcgacgc acatccgcgt gcgcaacccg cgcggcgagg gcgcgcggct
    47521 gcgggacgag atcgtcgcgg cggccgtcgc gctgctcgac gaaacgggcg acggcagtgc
    47581 gctgaccctg cggtcggtgg cgcggcgggc cgggatcgcg gcgccctcga tctatcggca
    47641 tttcccgcac caatcggcga tcatgcccgc ggtcgtgcgc gacgccttcg cgcagttgga
    47701 cgcccagttg cgggcggcag tgcgggccgc gggggactcg ccccgggatc gtttggccgc
    47761 agtgtgtttc ggctatctgg agttcgcccg tgctcgtccg gggcgctacc gcatcatgtt
    47821 cggcggtggc tgggtgcccg accgcgacga cggcgccgtc tccgagggtg aaatggcagt
    47881 cctggggcag tcgagcctgc gattgctggc ggcggccctc accgattgtg ttgccgcggg
    47941 ccaggctcgg agcgcggacc cggcggtgga cgcggtggcg ctgtggctcg ggctgcacgg
    48001 cctcgcacat cagcgtgcgg tcgcgccgtc tttcccctgg cccgccggga tcgtcgaacg
    48061 tctcgtcagc acgctcgcgc atctgaccgc tccgtgagtg tgcctcggtc gaggtgaaac
    48121 gcattgcgat gtaacgggtt cggggagcgg cagggccgct accggcccct cgggtggccg
    48181 gtgtggacgc tgggggatat gctctgcgag atgactactc attctgtcga aagattgggg
    48241 gttccattcg tgcacggtga gcgctgatgc ccaccgacac tgcgaatggg gacctttccc
    48301 gcctctcctt ctggtcgcgc gtacgtgaat tcgccgtgcc gccaggaatg atcgagactg
    48361 ccaccgcccg tcgcctgcgg ggtgattggg ccggcgcatg cgctgcggca ggcttcgata
    48421 tcgatctcga cctgcgctcg acagcgcgga cccgcgggcg cgaactcgcc gcgcggatcc
    48481 ggtccgacct gcgatatctg gcgccggacc tgctgcgctg gcacctaccg cggatcgcgc
    48541 cggatgggct gctgcgaccc gggttgacca gcaccctcgc gcgctacccg cacgcagggc
    48601 acgaacgcgg cagcccgccg ggcctcgaac tcgtggtgcg caccgcgccc gcctgggcgg
    48661 acgcgggcca gcggatcagc ctggcgctat ccgacggttc tgcgaaaacg gcggcggcac
    48721 aaccgcatcc gcatcctcgg ccggaccgcc ggtatcgcct ggatctgcac cgccacctct
    48781 gggacgcgcg gcgcaccgac gagttgcggg cacggtgcgg ggccggggaa ccacctgccg
    48841 gtcccgatcc cgaactcctc gtgctcttgc ccccgtccgg cgggtgtgcg gccgagacct
    48901 gggcggtcga agcgcggctg ctactggacg ccgagaagtg ttgcggcagt gcgttcgtcg
    48961 tacggctcgg gggtcggcga cgactggtgc tgcgggtcga cggcggggga ccgcccaccg
    49021 tgcggctcgc gccgggctat ccggcgggcg gcgtcaccgc gttaccggtg ctgccagacg
    49081 ccgcgacctg gacgctgccc gacctgaccc tgctaagtgc cggtgcgatc acgtccgatc
    49141 ggctgcaccc gctggtcgcg gcggcactgg cacccggtgg ctccgctgtg gtgcagcaga
    49201 cctacgcggt ggccggaccg cgcctggtga cctgccgcgg cgaacagcac cgcatcggtt
    49261 tcgtcgacgg tgtcctgtcc gcgctcgacc acgacccgat ggaactccgg cgggaggaac
    49321 tgctggccgc gctgtcgggg acgccgttgc cgtgcttgca ggccatcgat gtggcacacc
    49381 gtgcaccgga ctgcctggcg ggcatccggg aacgattgca ccacggcgat atcgcgggcg
    49441 cgctggcctt ggtcgaggga ctgctcggtc ccggtgcgct gctgcgcgac ggcgcactgc
    49501 ggg
//
