LOCUS       NC_018681              24144 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3554749
            Orig. end                         :: 3578893
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24144
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24144
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24144
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14144](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14144)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    119..135
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.15"
                     /tool="antismash"
     misc_feature    complement(348..362)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    complement(1079..1094)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
     misc_feature    complement(1247..1262)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            complement(1867..3660)
                     /locus_tag="O3I_RS16125"
                     /old_locus_tag="O3I_015930"
     CDS             complement(1867..3660)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019604.4"
                     /locus_tag="O3I_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015930"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_014984002.1"
                     /transl_table=11
                     /translation="MVGAGLAGTATAIRLLRFATEPVEIVLLERQKEHRHAGVAYHAAG
                     NPWNHIFNIQAGRMSAFREDVDDFLNWANGEADRSAWPPEWREVTFFESDPAPRRIYAD
                     YLGRRLAEAAAEAADGVVLREADGEMVELTPATDSISAVIENLSWSGGPGLESTTIDAD
                     HIILATGPELRHPRYAQAVLDHPSYIRLPYTGEAVERIRTLPPHAVVAIIGTLLSAYDF
                     AALLLRQGHAGAIYMISPSSSTPRTYPADHRHRVLAVPPPIIDVEQGRAALAGQLEAEW
                     IRACLFVAEQHPEVHPAVISERVAKAWEAYLPDIFQNISAEDLQFLLEKYGSRLATLRV
                     SAMSYTTAVVDAAHRASGQVQVVAGRVTDVRPLEQDRLLLTLSGDGPHRTLAADLVISN
                     FGREFDYAEVASRLWQCLLGRGLAVPHRKTRRGVEVDRFGALLMADGRRSEAISAVGAP
                     REGDEILRHGRLGAFSFNLATIKNHSVSVAADVLRKLESRYTSLPDSTTTPPLESAWAE
                     LVSLEVQRLAARRRRTRTEFQEQLDTKLREATGQSDISTWLAAINRAAVDCLTELSVTP
                     RELRAQLMLDLRSATSDRTLQ"
     misc_feature    complement(3049..3051)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            4208..5071
                     /locus_tag="O3I_RS16130"
                     /old_locus_tag="O3I_015935"
     CDS             4208..5071
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (43-174). E-value:
                     3.4e-09. Score: 28.6. Matches aSDomain:
                     nrpspksdomains_O3I_RS16130_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019045550.1"
                     /locus_tag="O3I_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015935"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_014984003.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-05, bitscore: 23.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.6e-07, bitscore:
                     30.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATYVLQTPGADITYDVFGPLPTTDRRPPLFLIAQPMDASGFRAL
                     REQFPERTVITYDPRGLGRSVRKDGRVEHEPDEQAGDVHAVIEVLGAGPVEMFASSGGG
                     VTALALVAAYPGDVTVLVVHEPPLLTLLPDAEAAARARQAMHDIYLAEGFGAGMAAFIT
                     MTSWEGEYTDDYFAQSPPDPAMFGIPAQDDGSRDDPLLSDRAWAVSDYRPDLAALTAAP
                     TRVVIAVGEESANTCTGRAAIATAEMLGQQATVFPSHHGGFMDGEFGYAGKPEAFAATL
                     REVLDN"
     aSDomain        4337..4729
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS16130_Abhydrolase_1.1"
                     /evalue="3.40E-09"
                     /label="O3I_RS16130_Abhydrolase_1.1"
                     /locus_tag="O3I_RS16130"
                     /protein_end="174"
                     /protein_start="43"
                     /score="28.6"
                     /tool="antismash"
                     /translation="ALREQFPERTVITYDPRGLGRSVRKDGRVEHEPDEQAGDVHAVIE
                     VLGAGPVEMFASSGGGVTALALVAAYPGDVTVLVVHEPPLLTLLPDAEAAARARQAMHD
                     IYLAEGFGAGMAAFITMTSWEGEYTDD"
     gene            5212..5586
                     /locus_tag="O3I_RS16135"
                     /old_locus_tag="O3I_015940"
     CDS             5212..5586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011206820.1"
                     /locus_tag="O3I_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015940"
                     /product="VOC family protein"
                     /protein_id="WP_014984004.1"
                     /transl_table=11
                     /translation="MADSSGMQVGMFSFDCRDAAALAEFWAAVLQRTVDPGATTEFATI
                     GFDGGGPTWMFHRPDGEPAAGPNRLMLDLGGEPDWAEQADRIEALGAERISDNDLDGVR
                     WVVFHDPEGNTFRIFAPRPV"
     gene            complement(5680..6894)
                     /locus_tag="O3I_RS16140"
                     /old_locus_tag="O3I_015945"
     CDS             complement(5680..6894)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011777957.1"
                     /locus_tag="O3I_RS16140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015945"
                     /product="cytochrome P450"
                     /protein_id="WP_014984005.1"
                     /sec_met_domain="p450 (E-value: 5.7e-29, bitscore: 100.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSKTPLHLVHAARERYSPGPALAERAHTDGLTRTDTPFGGPAWL
                     VTRHEDVRAVLGDAARFSSATADRRANPPAAQSDTDSAGKQFASAASFLVGQDPPEHTR
                     LRRLLTPEFTMRRMRELAPRVRAVVSEVLDAMQDAGSPVDLVERFALPVPSLVICELLG
                     VPYADREMFQHLTAVQLRVTAAQDERTDAFLALRSYMGDLVDRHRSAPGADLIGMLIRE
                     HDDDITHDELVGVALVLLIAGHETTANTLGAGTALLLEHPEQLAAVRDEPHQVDGAVEE
                     LLRFFTPVHTGLARTVTTDTVIGGQQMKTGDLVVVSLPMANRDPRLVTAPDDFDIARKP
                     APHVAFGHGIHHCVGAPLARMELRIALPALLQRFPGLRLDLDPADIQFRTMTAVHGVER
                     LPVAW"
     gene            7103..7726
                     /locus_tag="O3I_RS16145"
                     /old_locus_tag="O3I_015950"
     CDS             7103..7726
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019512815.1"
                     /locus_tag="O3I_RS16145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015950"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_014984006.1"
                     /transl_table=11
                     /translation="MPNKGDRGGSKTRARIAEVAQELFVGRGFDNVTIADVAAAAGVSK
                     VTVFAHFERKEDLLFDRLPDVVEIVRNAIRGRVDTIDAVEALRRAAVALGEERHVLSGL
                     AGDIEPMMRTVTASPALIARLRAFASEIETALTAELDQDPAFSGDSALAAALLVAAYRT
                     VAVDTVRRRLAGDDLAHLTATHRQRLNQAFDAVEHGISGGHPAI"
     gene            complement(7734..8036)
                     /locus_tag="O3I_RS16150"
                     /old_locus_tag="O3I_015955"
     CDS             complement(7734..8036)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS16150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_015955"
                     /product="hypothetical protein"
                     /protein_id="WP_141692326.1"
                     /transl_table=11
                     /translation="MSFNAPFVIVDRLGGPEPGDYYIQVHLDEDVDPADGHSYIIEFRD
                     GGPDAHFRATTSDDAPWDSVCSPAFDTVVKVVQDWAFQREGWRTALPWEQVRFDS"
     gene            8343..8747
                     /locus_tag="O3I_RS16155"
                     /old_locus_tag="O3I_015960"
     CDS             8343..8747
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025887.4"
                     /locus_tag="O3I_RS16155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015960"
                     /product="DUF4440 domain-containing protein"
                     /protein_id="WP_014984008.1"
                     /transl_table=11
                     /translation="MTVDVAGLVIKAEHDRIQCLLDVDRGAYDRLHAAEYRLCNPTGTV
                     WTKAAYLDLLTTGRVVYRELRLIGDMDAIVGTDVVVLRYQCVIELVVDGASIPRHEAWH
                     TDVYTNAGGPWRCVWSQATGIIRVQPVAPT"
     gene            complement(8744..9736)
                     /locus_tag="O3I_RS16160"
                     /old_locus_tag="O3I_015965"
     CDS             complement(8744..9736)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011206712.1"
                     /locus_tag="O3I_RS16160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015965"
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_051066631.1"
                     /transl_table=11
                     /translation="MRRVVFSVGRGKVPGWRRRAGVILAAAVLVSGIGATATAAPVHGP
                     VLRAPAGGYQELLVPSSMGPIKVQVQWASRGGSSALYFLDGLRAPADHSQWTSDTDALR
                     QFAGDNVTLVFPVGGHSSFYTDWYRPSSTNSQPTTYRWETFLTRELPDFLAGYGVSRTN
                     NAIVGASMGGNAALTLAGHHRDQFKFAGSFSGFVHPTFPMWNEAMRAAMLDEGRFNVDD
                     MWGPAGTPAWFRNDATVQAELLRGLPIYVSTGNGLPGPLDAPNAITDTINGVALEAMTV
                     AATRIFRDRLATLNIPARIDITDGTHTWPYWQNSLATARPAILDALNAH"
     misc_feature    9729..9745
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.35"
                     /tool="antismash"
     gene            complement(10001..10786)
                     /locus_tag="O3I_RS43820"
     CDS             complement(10001..10786)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TS_UbiA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013226.4"
                     /locus_tag="O3I_RS43820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_167829145.1"
                     /sec_met_domain="TS_UbiA (E-value: 9.9e-49, bitscore:
                     164.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ubiA (E-value: 9.7e-14, bitscore: 50.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVPALTIGVAASAKDGLSFRLAAIKLALVSIFALAYLLLHCLVS
                     QVDSLDEDRINKPWRPLPAGRISLKSAVKARNLAIISFPLIGYLLDVFVQALIWELTVI
                     LACYTHWTNNVFGKCSYSLIGALVLTGYWQIVAPMTVEVRDDFILMGIATFFSISVQDF
                     RDKTGDLIAGRRTLPILLGDGPSRLLGVTALASLPFVNYMITNPTMHNALSWAAFSLPT
                     ACAAVSALFLSVPRNKRTDHLAYRFLECWFALSFLGMAF"
     misc_feature    complement(10016..10018)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10091..10093)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10682..10684)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(10706..10708)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10967..10982
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.67"
                     /tool="antismash"
     gene            complement(11009..12130)
                     /locus_tag="O3I_RS16165"
                     /old_locus_tag="O3I_015970"
     CDS             complement(11009..12130)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983661.1"
                     /locus_tag="O3I_RS16165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015970"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_141692327.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.3e-46, bitscore:
                     157.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADPDAATAIDLARVRVMVDRTLDKFLTDKATIAERQHLPPEMI
                     GALHAFVGSGAKRLRPQLCVLGWLAAAGDPDLPLSVVRCAAAIELCHTAILIHDDIIDH
                     SDTRRGRPTVHRALEQRRPAHSNSAEFGVHAAILLGDLAMVWADELLHHAQLTGTQAET
                     VLPLFDSMRTSVNYGQYLDLLTTNCAEANLQRALEIIEHKTTSYTFEGPLRIGAALAGA
                     PPTVHAALVAYARPLGIAIQLQNDLLDTYGSQDQTIRPSLSDLREGKCTALLAIALTRA
                     TPDQRARLQQIVGKPTMDDTDATECKEILDQVSRNEVDEMVRTRWNQAKKALHYSPFPL
                     HVIQTLAHVAEIVALGTINNADTAVRYTTSPQA"
     gene            complement(12127..13044)
                     /locus_tag="O3I_RS16170"
                     /old_locus_tag="O3I_015975"
     CDS             complement(12127..13044)
                     /NRPS_PKS="Domain: oMT (95-256). E-value: 1.2e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_O3I_RS16170_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983542.1"
                     /locus_tag="O3I_RS16170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015975"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_014984011.1"
                     /transl_table=11
                     /translation="MTTDATFSTNIARTPYEKELRQHWDSKQHDDVNLLLGELDGLYHH
                     HFGYGDYDPAVLLGEGQQREQKMIAELHRLESDQVSLILDVLGDIGPEHCVMDAGSGRG
                     GTSFMIHDRYGCAIDGVNFSQYQIAFAEQLAEQRHCADRVRFHYQNMAATTFPDGHFHR
                     VISNETTMYGDLYEFFSEFSRVLTPGGRYVAVTWCRDDAVEFSSPDVEQIDQHYVCHVH
                     RRSTYFKALAAAGLAPIHVEDFTEQALPYWELREQSSLATGVEQPYLSAYRAGHMNYLL
                     IVADRVVPDQPSSRPLRNPKGNNE"
     aSDomain        complement(12277..12759)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS16170_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.20E-16"
                     /label="O3I_RS16170_oMT.1"
                     /locus_tag="O3I_RS16170"
                     /protein_end="256"
                     /protein_start="95"
                     /score="51.7"
                     /tool="antismash"
                     /translation="VMDAGSGRGGTSFMIHDRYGCAIDGVNFSQYQIAFAEQLAEQRHC
                     ADRVRFHYQNMAATTFPDGHFHRVISNETTMYGDLYEFFSEFSRVLTPGGRYVAVTWCR
                     DDAVEFSSPDVEQIDQHYVCHVHRRSTYFKALAAAGLAPIHVEDFTEQALPYWELRE"
     gene            complement(13107..14144)
                     /locus_tag="O3I_RS16175"
     CDS             complement(13107..14144)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014987551.1"
                     /locus_tag="O3I_RS16175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_041562649.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.6e-56, bitscore:
                     188.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLARDAERREGATILEDARRIIEPEYRAVVRHLPAEVSHIGGYH
                     IGWWDAAGRPTTSSGKAIRPALTLTSTAALADGTIERHKDRVVAAAVSVELIHDFTQLH
                     DDVMDGDRTRRHRMTAWAQFGVGPAILTGDMFLASALETLAQHDVAAVDILAQALRGLC
                     EGQSADLAFEQRNSVDLDECIRMSECKTATLISASCALGAWAAHADASRATCLAAFGLH
                     IGRAFQLVDDLLGVFGDPDSTGKPLYADLIRRKKSLPVVAALNSDTVAGRRLSQRYADT
                     EPFAGDELARLAQLIVDAGGKQWAEVAARRSRIEAEKSLLAADPETSAAADLLTLADLI
                     LSRDH"
     misc_feature    complement(14136..14138)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14756..14769
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.09"
                     /tool="antismash"
     misc_feature    15060..15073
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.16"
                     /tool="antismash"
     gene            15204..16415
                     /locus_tag="O3I_RS43825"
                     /old_locus_tag="O3I_015990"
     CDS             15204..16415
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="O3I_RS43825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015990"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_014984014.1"
                     /transl_table=11
                     /translation="MQSQRSDHPAGGLSIGSRIEFRRRQCGLSRRVVANLVGRSEEWLR
                     LVEIGRQSLDSVRLIVRLADVLRIENIGELIEWPTHHTLTRPDDGRKIVSSYAQALLSG
                     DPPPSSGDVSLNSLNADLSRCIEIWESSAKPYTLTVEILPSLIAGSNHLYWMTHDPSVG
                     QVSVRAHQLACMLLSRLGSFTIAVIAAERCVNVAKSVGEPILVATSSLHRASAMLALGH
                     SLQSIYLSHSANKPYTVDFREMAIEGSRLLVAATAAAGKNDVRAADECIDRAIGIANNL
                     RVESRVGEFNFGMTAIGLTRMKIALLRSEIAEIPRIAALMEIPESYPPACISEFHIILA
                     YAFCQKNEDVAAAYSLSRAADLCPEEIFLNPCAREVIEILIHRQNNLVRQDITRLLSRI
                     ALFD"
     misc_feature    16119..16121
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16218..16220
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16269..16271
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            complement(17210..17286)
                     /anticodon=(pos:complement(3571999..3572001),aa:Pro,
                     seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="O3I_RS16180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="O3I_0t42227"
                     /product="tRNA-Pro"
     gene            complement(17210..17286)
                     /locus_tag="O3I_RS16180"
                     /old_locus_tag="O3I_0t42227"
     gene            17491..18231
                     /locus_tag="O3I_RS16185"
                     /old_locus_tag="O3I_015995"
     CDS             17491..18231
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019932854.1"
                     /locus_tag="O3I_RS16185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_015995"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_014984015.1"
                     /transl_table=11
                     /translation="MRRERRLVEAFVQLADSLVEEYDPVDVVQGLLDRAVDLLEVDTAA
                     VLLARDDGELRVLASTSEAARWLELLQIQAQDGPCLQCYRTSERVIAEDLAAAQDRWPA
                     FAKQALVEGFRSVYALPMRLRADRVGALNLFSYGETRLSEDDLVVGQAMADIASIAILR
                     ARQLADHKTVNGQLQSALQTRIVIEQAKGILAAQGDLDPETAFHALRGYARHSRGRLPD
                     LARAVVERTIDARVILAHGNHRPG"
     misc_feature    complement(18309..18324)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.42"
                     /tool="antismash"
     gene            18410..19066
                     /locus_tag="O3I_RS16190"
                     /old_locus_tag="O3I_016000"
     CDS             18410..19066
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="O3I_RS16190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_016000"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_141692328.1"
                     /transl_table=11
                     /translation="MGEEVGGRVYRGRSADERASERRRRMLDAAVELFGGRGYPGTSIG
                     ELCTAARVSYRSFYEEFGALDQLLIAAVDEFDARAAERVVAALVETDEADFATRAAVTF
                     RAFLAATCPSRKAARMCFVEIVRVADTVEIWRRERRRRFARLFVSQAEIAAERGEIASR
                     PFAFAAIATMGAVIYAIQEWVNAEPVFAEFVGADTDELADQLARIYLDAVGPLLP"
     gene            complement(19068..20297)
                     /locus_tag="O3I_RS16195"
                     /old_locus_tag="O3I_016005"
     CDS             complement(19068..20297)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="O3I_RS16195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_016005"
                     /product="acyltransferase"
                     /protein_id="WP_014984017.1"
                     /transl_table=11
                     /translation="MTIEETRAPVGLAAQRPAQLPSLTGMRWWAASAVFALHAVVFLPA
                     YPFQHSETFRRIHAVLPMQLGAAGVTFFFVLSGFILCWNRRPGDSAKSFLRRRFLKIYP
                     THVLALVLLLVVAPVPLARTVVWLPNLLLIHTWVPGWTALGGLNVPSWSLVAEVLFYLS
                     FPVLAPYVDRLRDNQILPCLIAVFLVIVALHCAFYLFADGPKGVTNIFVPRLLPGEVTP
                     EHEIHSAPVWFAQDAIPVTPSYWLSYNFPPSRLLEFYIGALTAKLVMVGRFTATRYRHP
                     LLLLAAGYALTWVVPLNFKLSVPIILPAAYVIATACCRDTAGYRGLNASRPLVWLGDLS
                     FAFYLVQYPIMVTVTQTWMSGHRYDIRGWLAWSAVCLVLSITLAAAIFRYLDRPITQWA
                     RSIDRRQRAA"
     gene            complement(20294..21196)
                     /locus_tag="O3I_RS16200"
                     /old_locus_tag="O3I_016010"
     CDS             complement(20294..21196)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024863.4"
                     /locus_tag="O3I_RS16200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_016010"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_014984018.1"
                     /transl_table=11
                     /translation="MQPNSMIARLCIAATATLCAMAHAATASATPAPGGARIVVLGDSF
                     ASNSIGTDQHSNQCDRNPRSWPNQLAQTTGATMVDVSCAGAALDTGTGWNLAQQARKAA
                     DAAAFGTGTEAVLLQFGLNDIWGDNDVVALNVVLRCAINLLEGCEPDAAGQGRLPDLSR
                     ITPENYAARIARVIEYVRYYAPHARIALVGYPEFFEPTSTTACLGLFGLGTVTQPRAAG
                     LAAYLAALRAATAGAAAALGIEYFDTAAAYRGHGMCATEPWLNGIGDPRAELFGIPGHP
                     SRHGDAATAGGIRQMLGLA"
     misc_feature    complement(20375..20377)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21229..21561)
                     /locus_tag="O3I_RS16205"
     CDS             complement(21229..21561)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS16205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_041562651.1"
                     /transl_table=11
                     /translation="MNAPRIAAALTAGTLLASSWLLTACSSDTSAPTPAATTSRGAPTS
                     VPAPSTEVPHPPSTVPIPSPTTTFPVPSTVMPPMYRPPVSEAPRPPEPQAPPELPNPGF
                     APRPGY"
     misc_feature    complement(21655..21672)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.69"
                     /tool="antismash"
     misc_feature    complement(21698..21713)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            21937..23313
                     /locus_tag="O3I_RS16210"
                     /old_locus_tag="O3I_016020"
     CDS             21937..23313
                     /GO_function="GO:0004806 - triglyceride lipase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014988663.1"
                     /locus_tag="O3I_RS16210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_016020"
                     /product="lipase family protein"
                     /protein_id="WP_014984020.1"
                     /transl_table=11
                     /translation="MTLAALLCVAVLASAPALGHAAPAPRDVPIAPLPVLVLPPELDPF
                     YKAPANVIADTPPGGIIKARMITPALLSLVPFNIDAWQLLYRTNDSHGNPIATVTTVVK
                     PRGPAPAEGFKLLSYQVAEDSTAQYCAMSYVVQQGSIPVDYVNSAEVSLAIALGISQGW
                     VVSIPDYQGPGSAYGAAILGGQATLDGIRATQNFIPAQLTPDARVGVMGYSGGSIPTGW
                     VAENHGEYAPEINIVGVTMGGVAMADLRAVLRSNNFNLGAGLIGAALRGFATEYPEVQH
                     VLDTRYDWFGRFMTSIKGMLCHTQGSAFFPWWNYLGSYTGPGDVLDIPELSAAITAQEL
                     GKRDPDVPMYIYQAQNDEFIPSPGVDRLVDKYCRNPEVSLGYTREFFAEHVVGIPGWLP
                     KGYQFIIDRLNDVPVNPGCAIDSPFSTFTDGDFIALLAETWPAIAGLVTGLPVGAGTHP
                     "
ORIGIN
        1 ggtgatgcgg agttggacga gggggcggtg tgggaggccg tcgtcgatcc cggtaacgcc
       61 gatctcggtg agatcgtgtg gatcgtcgat ctgaaccgtc agtccctgga ccgggtggtg
      121 cccaatatcg ctgccggtcg gctggaggcg atgttcgccg ccgcgggctg gcaggtgctc
      181 acggtgaagt tcgggcgtct gctggaatcg ttgttcgctc ggccgggtgg cgccgcgctg
      241 cgcgcccgga tcctcgacat gcccaaccct gagtaccagc gtctgctgcg ctgcgacgcc
      301 gacgaactac ggcgcaggct gccgggcagc ggacctgacc atgcgcaatt gacggaattg
      361 attgcaggtc tggatgattc gacactcttg gcggcgatcc gcaatctagg tgggcacgat
      421 atgcaggcct tgatcgaggc ctacgcccag atcgacgaca cccgtccgac ggtgatcatc
      481 gcctacacca tcaaaggcta tgggctgccg acacaaggac atccgcagaa ccattcgtcg
      541 ctgctgtcgg tggccgagta cgaatcgctc gccgccgaac tcggccgcga tccacagcac
      601 ccgtgggcgc ggctcaacga cgacagcgcg gccggacgat tatgcgcgga gaccgcgctg
      661 cggttgcgtc gcgaaccggt gcattcggtc gaagtacccg aggtaccaaa ggatttcggc
      721 catacaccga aaagtatcgc gaccacgcag gcggcgctgg ggcggactct gctggacctg
      781 agccgggcgg cgccggagat ggcgcggcgg gtgatcaccg tgagtcccga cgtcagctcc
      841 accaccaatc tggcgggctg gatcaacaag gtcggtgtgt ggtcgagcgc cgaacggcac
      901 gactggttcg ccgacgacgc cgaaacgctc gtgcggtggc gtgagcaacc caccggtcgg
      961 cacatggaac tcggtatcgc cgaaacgaat ctggtcgggc tgatcggcga actcggcgcg
     1021 acctggagcc ggtggggcca acccctgttc ccgatcggtg tgctctacga cccgttcgtc
     1081 gaacgcgcgc tcgaaccctg gacctacggc atctacgccg gcgggcagtc gatcctgatc
     1141 gggacgccgt ccggtgtcac cctcgccgcc gaaggtggtg cccaccaatc gattacgacg
     1201 ccctcgatcg gtatcgagac gccgggcctg atctgttacg aacccgcgtt cgccatcgac
     1261 gtggaatgga cgctgctggc cagtatcgcc cggctcgggc gaccggacgg gacctcggcg
     1321 tatctgcggc tgtcgacccg gccggtcgaa cagcgcctcg ccgaggtgcc cgccgaccct
     1381 gccgcgcggg agcgtcgtcg caaacaggtg gtggcaggcg gatatccgct gcgccggcgc
     1441 gcggacgcgg tcgtcacgat cgtcgcgatg ggcgccgtgg tgaccgaggc ggtggccgcg
     1501 gccgaccggc tcgaatcggg cggggttgtc gccgacatcg tgtgcgtcac cagtcccggg
     1561 ctgctcttcg aggcatcgca ggccaggcaa ggccgcggcc acggggacag ctggatcctg
     1621 gatcagctgt tcccgcccag ccgggccacg ccgatggtga ccgtgctgga cggccacccg
     1681 cacaccatgt ctttcctgtc cgggatcaat cgggtgcatc acatcgatct cggcgtgacg
     1741 cgttacgggc aagtcggatc gctcgaggag gtgtaccgct accacgggtt ggacgccgac
     1801 agcattgtcg ccgccgccct cgacgtgctc ggcgcggccg gttgaggttc agggcaccac
     1861 acccgcctac tggagtgtcc ggtcagacgt tgccgatcgg aggtcgagca tgagctgggc
     1921 gcgcagttcc cgcggcgtca cggagagttc ggtcaagcag tcgacggcgg ctcgatttat
     1981 cgcggccagc caggtgctga tatcggattg tccggtggcc tcgcggagct tcgtatccaa
     2041 ctgttcctga aactcggtgc gagtccgccg ccggcgcgcc gccaagcgct ggacctccag
     2101 cgaaaccagt tcggcccatg cgctttccag cggtggagtc gtggtggagt cgggcaggct
     2161 cgtgtatctc gattcgagtt tgcgcagcac atccgcggcc accgaaacgg aatggttctt
     2221 gatggtggcc agattgaaac tgaaggcgcc gagccgtccg tgccgaagaa tttcgtcgcc
     2281 ttcccggggc gcgcccactg cggagatcgc ttcggaccta cggccatcag ccatgagcaa
     2341 ggcgccgaac ctgtctacct ccacgcctcg tcgagtcttc cggtgcggaa cggccagccc
     2401 gcgcccgagg aggcattgcc acagccgaga ggccacctcg gcatagtcga actcccggcc
     2461 gaaattggag atgaccaggt ctgccgccaa ggttcggtgc ggcccgtcgc cggagagcgt
     2521 cagcaacaat cggtcttgct cgagcggccg cacatcggtg acgcgaccgg cgaccacctg
     2581 gacctggccg ctcgcgcggt gcgcggcatc cacgacggcg gtggtgtacg acatcgcact
     2641 gacccgcagc gtggcgagac ggctgccgta cttttccaag aggaactgca agtcttcagc
     2701 ggagatgttc tggaatatgt cgggcagata cgcttcccag gctttcgcga ctcgctccga
     2761 aatcacggct gggtgcactt cgggatgctg ctcggcaacg aaaagacatg ccctgatcca
     2821 ctcggcttcg agttggccgg cgagagccgc acgtccctgc tcgacgtcga tgatgggtgg
     2881 cgggacggcc agtacgcgat gccggtggtc ggccgggtag gttctcggcg tcgagctcga
     2941 cggcgagatc atgtatatcg caccggcgtg cccttgtcgt agcagcagcg cagcgaaatc
     3001 gtaagcgctg agcagtgttc cgatgatcgc gacgacagca tgcggcggta atgtcctgat
     3061 tcgctccact gcctcgccgg tgtagggcag ccgaatgtag gacgggtgat cgagcacggc
     3121 ctgtgcgtag cgcgggtggc gcagttcggg ccccgtcgcg aggattatgt ggtctgcgtc
     3181 tatggtcgtc gattcgagac cggggcctcc cgaccaggac agattttcga tcacggcgga
     3241 aatgctgtcc gtagccggcg tcagctcgac catttcaccg tctgcctcgc gcaggacgac
     3301 gccgtcagcg gcttccgcgg cggcttcggc cagtcgtcga ccgaggtaat ccgcgtaaat
     3361 ccggcgcggt gccggatccg attcgaagaa ggtgacttcc cgccattccg gcggccacgc
     3421 cgatcgatcg gcttctccgt tggcccaatt caagaagtcg tcgacatcct cccggaaagc
     3481 agacatcctg cccgcttgga tgttgaagat gtggttccac ggatttcccg ccgcgtgata
     3541 cgcgactccc gcgtgtctgt gttccttctg gcgttccagc aggacaattt ccacaggctc
     3601 ggtggcgaag cgcagcagtc ggatggctgt tgcggtgccg gccagacctg caccgaccac
     3661 gacgatgcgc cgggaccttc gaggtgcccc cgcctgattg gctgctatcc gcacgatgac
     3721 ggcgagagct gacgtacggc gtcgagcagc accgagcgta gcctggccga gaaccttagt
     3781 gccgctgagg aagtcgtcgt acggggcggc acgacgtcag cgtgtgccgc gagaacccct
     3841 gccgggccgg gctcagaaac atccgcggct gtcgccagcg caaacatcat gcgcgaagta
     3901 ttcctcatcg tcgatgatct tgaccctgca atagcctcat tctgttcggc acgaacccgg
     3961 agcggtatcg gccgcaaggc cggaccaccg tttcgcgacg atctggtggc gcgggagttc
     4021 cgctccgcag caacgggtca cacggatcga gccggttcgc ggtgcacccg tagggcgggc
     4081 gaccggcatc gccggcatag cagtgttcgc tgagtactag ggcgggggcg agatgcaccg
     4141 ccggcaatcg ccggacgaac cagctcgccg ccgatgaatt ttccggacat gccccgtcgt
     4201 atcagatatg gctacatatg tcctgcagac ccccggtgcg gatatcacct acgacgtgtt
     4261 cggtccgctg cccaccacgg acaggcgacc accgctgttc ctgatcgcgc agccgatgga
     4321 cgccagcggc tttcgggcac tgcgggagca gttccccgaa cgcaccgtga tcacctacga
     4381 cccacgcggg ctcggccgca gcgtccgcaa ggacggcagg gtcgagcacg aaccggacga
     4441 acaggcaggc gacgtgcacg cggtgatcga agtgctgggc gcaggcccgg tcgagatgtt
     4501 cgccagcagt ggcggcgggg tcacggcgtt ggcgcttgtc gcggcctatc cgggcgacgt
     4561 gacggttttg gtggtgcacg agcccccgtt gctcaccctg ctgcccgatg ccgaagcggc
     4621 ggcacgcgcc aggcaagcca tgcacgacat ctatctggcc gaaggattcg gtgcgggcat
     4681 ggcggctttc atcacgatga cgtcgtggga aggtgagtac accgacgact acttcgccca
     4741 gtccccgccg gacccggcca tgttcgggat acccgcgcag gacgacggtt ctcgcgacga
     4801 cccgctgctg tcggaccggg cctgggcggt gagtgactac cgccccgacc tcgcggcgct
     4861 gaccgccgcc ccgacccgcg tcgtgatcgc cgtcggcgag gaatccgcga acacctgcac
     4921 cggccgcgcc gccatcgcca cagctgaaat gctcggccaa caggcgacag tattccccag
     4981 ccatcacggc ggcttcatgg acggtgaatt cggctacgcg ggcaaaccgg aggcgttcgc
     5041 ggcgaccctg cgcgaggtgc tcgacaactg atacgtacac gtggcttctt tgtgaaactg
     5101 cgatgctgac cgctggagtg ccggccgatg catccggatg gccggcatcg tctcaattgc
     5161 tatggtgcgc ggcacattcg ggtgccgtga tcttacggaa ggatgcgtga catggctgat
     5221 tcgagcggca tgcaggtcgg gatgttttcc ttcgactgcc gcgacgcggc ggcgcttgcc
     5281 gagttctggg cggcggtgct gcagcgcacc gtcgatcccg gtgcgacaac ggaattcgcg
     5341 accatcggat tcgacggcgg cggaccgacg tggatgttcc accgacccga cggcgagccg
     5401 gccgccggcc ccaaccggct tatgctggat ctcggcgggg aaccggactg ggccgaacag
     5461 gccgaccgca tcgaggctct cggcgccgaa aggatcagcg acaacgatct cgatggggtc
     5521 cgctgggtcg tcttccatga tccggagggc aacacgttcc gtatcttcgc ccctcgtccc
     5581 gtctgaggtg ctctcacagt cagctggtcg gattcagccc cgccgccgac tacatttcta
     5641 tccggccgag accggcgtcg aatggcccgc agtgcgtgat caccaagcga caggcaacct
     5701 ttcgacgccg tgcacggcgg tcatggtgcg gaactggatg tctgccggat cgagatcgag
     5761 ccggagtccg gggaagcgtt gcaacagggc cgggagtgcg atccgtagtt ccatcctggc
     5821 caggggagcg ccgacgcagt ggtggatgcc atggccgaat gcgacgtgcg gggccggctt
     5881 gcgggcgatg tcgaaatcgt ccggtgcggt gaccaggcgc gggtcacggt tggccatggg
     5941 gagcgaaaca accaccaggt caccggtttt catctgctgt ccaccgatga cggtgtccgt
     6001 cgtgacggtc cgggccaggc cggtgtggac cggggtgaaa aagcggagca gttcctcgac
     6061 cgcaccgtcg acctgatgtg gctcgtcgcg gaccgcagcg agttgttcgg ggtgttcgag
     6121 aagcagagcg gtgcccgcac cgagggtgtt ggcggtcgtc tcatgccccg cgatcagcag
     6181 gacgagggcg acgccgacca gttcgtcgtg ggtgatgtcg tcatcgtgtt cgcgaatgag
     6241 catcccgatc agatcagcac ccggagcact gcgatgccgg tcgacgagat cgcccatata
     6301 agaacgcagc gcgaggaagg cgtcggtccg ctcgtcttgc gcggccgtga cccgaagctg
     6361 caccgccgtc agatgttgga acatctcccg gtcggcatag gggacgccga ggagttcgca
     6421 gatgaccagg gaggggacgg gcagtgcgaa gcgctcgacg aggtcgaccg gcgagcccgc
     6481 gtcctgcatc gcgtcgagga cctcgctgac aacggcccgc acccgaggcg ccagctcacg
     6541 catacggcgc atcgtgaatt cgggggtgag cagtcggcgc aggcgggtgt gttcgggtgg
     6601 atcctggccg accagaaacg atgccgcact ggcgaactgc ttgcctgccg agtcggtatc
     6661 ggattgcgcg gcgggaggat tcgcgcgacg gtcggcagtc gcgctgctga accgggcggc
     6721 gtcaccgagt acggcgcgca cgtcctcgtg gcgggtgacc agccaagccg gtccaccgaa
     6781 gggcgtgtcc gttctggtga ggccgtctgt gtgcgctcgc tcggccagag cgggccccgg
     6841 gctgtaccgc tcccgagcgg cgtgaacgag gtgcagcggc gtcttcgacg tcatggcttc
     6901 tcccatcgaa ccgcggccgg tacgggcgcc cggacctccg cgctgaagta aggtttactc
     6961 gataagctta tcaagtaagc ttacttgggc aagatggcgg aacggcgagc atcccgcgtg
     7021 tgccgcgtcc ctcctcatgg ccgttcctta cctggtaaat ttactttgta aagcttcgct
     7081 agcaggaggg agttccacgc gcatgccgaa taagggggac cgcggcgggt cgaagacgcg
     7141 agcgcgcatc gccgaggtcg cgcaggaact gttcgtggga cgcggcttcg acaacgtcac
     7201 gatcgccgat gtcgccgcgg cggcgggcgt gtccaaggtg acggtgttcg cgcatttcga
     7261 acggaaggaa gatcttttgt tcgaccgtct cccggacgtt gtcgagatcg tccgcaacgc
     7321 gatccgcggg cgcgtcgaca ccatcgacgc ggtcgaggcg ctgcgccggg ccgccgtcgc
     7381 gctcggtgag gagcggcacg tgctctcggg gctggccggg gacatcgaac cgatgatgcg
     7441 gaccgtcacg gcctcgcccg ccctgatcgc gcggctgcgc gccttcgcgt ccgagatcga
     7501 gacagcgctg accgccgagc tcgaccaaga ccccgcgttc tccggggaca gcgcgctcgc
     7561 ggcagccctg ctcgtcgccg cgtaccggac agtcgccgtc gacacggtgc gccgccggct
     7621 cgccggagac gatctcgccc acctcaccgc aacgcaccgt cagcgcttga accaggcttt
     7681 cgacgcggtc gagcacggca tctcaggcgg tcatcccgcg atctgaaccc gggtcaagag
     7741 tcgaaccgca cctgttccca cggcagggct gtccgccacc cctcgcgttg aaatgcccag
     7801 tcctgcacta ctttcaccac ggtgtcgaag gctggcgagc agacactgtc ccacggtgcg
     7861 tcgtcgctgg tcgtggcacg gaaatgggcg tcgggtccgc cgtcgcggaa ttcgattatg
     7921 tagctgtgac cgtcggcggg atccacgtcc tcatcgaggt gaacctgaat gtagtagtcg
     7981 ccgggttcgg ggccgccgag ccgatcgacg atcacgaacg gcgcattgaa gctcatgtcc
     8041 gccaggatgt cgtgcagctg ggtccgagag gggttctcga cagtccggtc ggaatcggtg
     8101 gcgaccactc gtggcgatcc ggttcggtct tggggcaccc gagcacggta cgtgcaagtc
     8161 ggcgacagcg cgaccgcgtt cgacccgggg tgcacgctgc ttcccatcag tgaagaatgg
     8221 tcgcggtcac cgggtttcgg tacgcggcaa gctggttcgt gtgggggcgg acccgaaggg
     8281 aaggctgatg acgagcagct cagcggtgtt cgttccggcc gaacgagtga ataggggcgg
     8341 gtatgaccgt cgatgtggcc ggcctggtga tcaaggctga gcacgatcgg atccaatgtc
     8401 tcctcgacgt ggatcgcggc gcctacgacc gcttgcacgc cgcggagtat cggttgtgca
     8461 atccgaccgg caccgtgtgg acgaaggccg catacctcga tctcctcacc accggacggg
     8521 tcgtctatcg ggagctgagg ctgatcggcg acatggacgc catcgtcggc accgacgtcg
     8581 tcgtcctccg ctaccagtgc gttatcgaac tcgtcgtcga cggcgcgagc atcccgcggc
     8641 acgaggcctg gcacaccgac gtctacacca acgccggcgg cccgtggcgt tgtgtctggt
     8701 cgcaggccac cggcatcatt cgcgtgcagc cggtggcacc gacctagtgc gcgttcagcg
     8761 cgtcgaggat ggcgggacgg gcggtggcca gggagttctg ccagtagggc caggtgtggg
     8821 tgccgtcggt gatgtcgatg cgggcaggga tgttcagggt ggccaggcgg tctcggaaga
     8881 ttcgggtcgc ggcgacggtc atggcttcga gggccacgcc gttgatggtg tcggtgatgg
     8941 cgttgggggc gtcgagagga ccggggaggc cgttgccggt ggagacgtag atcgggaggc
     9001 cgcgcagtag ttcggcctgg acggtggcgt cgttgcgaaa ccaggcggga gtgcctgcgg
     9061 gaccccacat gtcgtccacg ttgaagcggc cctcgtcgag catggcggcg cgcatcgcct
     9121 cgttccacat cgggaaggtg ggatgcacga aaccggagaa agagccggcg aatttgaatt
     9181 ggtcgcggtg gtggccggcc agggtgaggg cggcgttgcc gcccatggag gcaccgacga
     9241 tcgcattgtt ggttcgcgaa acaccgtagc ccgcaaggaa atcgggcagt tccctggtga
     9301 ggaaggtctc ccagcggtag gtggtcggct ggctgttggt gctgctcggc cggtaccagt
     9361 cggtgtagaa gctcgaatgg ccgccgaccg ggaacaccaa cgtgacgttg tcgccggcga
     9421 attggcgcag ggcgtcggtg tccgaggtcc actggctgtg atctgccggt gcgcggaggc
     9481 cgtcgaggaa gtacagcgcg gagctgccgc cgcgcgacgc ccactgcacc tgcaccttga
     9541 tggggcccat gctggacggc acgagcagct cttgatagcc gcctgcgggt gcacggagca
     9601 ctggtccgtg caccggtgcg gctgtcgccg tcgcaccgat ccccgacacg agtacagccg
     9661 cggccaagat aacgccggcc cgtcggcgcc aacccggcac cttcccccga cccaccgaaa
     9721 acaccactct gcgcatacct ttcaaccttc ccgcccgcga cccgaccggc agggacccga
     9781 attggcctgt cgcccaggct aactgtgcac cttgccaagt cgccaattcc caggtggggg
     9841 aaggtcggat cgggaacgcg tactcgaaca cagtgggtgc gggtcgcagt cctgcggggc
     9901 cgccgcgcgg acggcgaagg tctgggtccg cgtgccacgc gcggcctgcc agtcaggggc
     9961 agtcggcgtg agattcgatg tcaaggcgag gtgtcgagtc ttagaaagcc atgcctaaga
    10021 agctcaaagc aaaccagcat tctagaaacc ggtatgcgag gtggtctgta cgcttgttgc
    10081 gtgggactga taaaaaaagc gcggagactg ccgcgcaggc tgtaggaaga gaaaatgctg
    10141 cccaggacag agcattgtgc atcgtggggt tcgttatcat atagttgacg aagggaagag
    10201 atgcgagtgc tgtcacgccc agtagcctgg atggtccgtc tcccaatagt attggcagcg
    10261 ttctcctgcc tgcgattagg tcccctgtct tgtctcggaa gtcttgaacg ctaatactga
    10321 agaatgtggc gattcccatg agaataaaat cgtcacgaac ctccactgtc atgggtgcaa
    10381 ctatctgcca atagcctgtg agtacgagtg cgcctataag gctatatgag catttaccga
    10441 agacgttgtt ggtccagtgg gtgtagcaag ctagtataac cgtcagttcc caaatcagag
    10501 cctggacgaa cacgtctaga agatatccaa taagtggaaa agaaattatg gcgagattgc
    10561 gcgcttttac tgcggatttc aggctgatcc gaccggctgg cagggggcgc cagggcttat
    10621 tgatgcgatc ttcatcaagg ctgtcgacct ggctgacgag gcagtgtagc agcagatatg
    10681 ctaaggcgaa tatgcttacg agggctaatt tgattgcggc tagcctgaat gaaagtccat
    10741 ctttagcaga tgcggctact cctatggtta gtgccggtac aaacacggcc caatagtcgg
    10801 atttgataaa gagccagacc agtcgtattt gattgataat tgcgcttcac cccgctattc
    10861 tctgtgaggt ctgtcggtcg atctgcgctg ttgagccgtc aaaattgacg agaccctgag
    10921 ggtctgggaa atctagcagc tgcgggccag gctagtgttg gatcgggtgt acagttgaaa
    10981 tctgagatcg tgctccacga tgtgcaattc atgcttgcgg agatgtagtg tatcggactg
    11041 ctgtgtctgc attattgatg gtgccgagcg ccacgatttc ggccacatgc gctagcgttt
    11101 gaattacgtg caggggaaac ggtgaatagt gtagtgcttt tttagcttga ttccagcgtg
    11161 tgcgtaccat ttcgtcgacc tcgttgcggg atacttggtc gagtatttcc ttacattcgg
    11221 tcgcgtcggt atcgtccatc gtcggcttgc cgactatttg ctggagacgt gcgcgttgat
    11281 cgggtgttgc gcgcgtcagt gcgatcgcca gcaatgccgt gcattttccc tcccgcaggt
    11341 cgctcaggct gggcctgatc gtttggtctt gacttccgta agtatcgagc aggtcgtttt
    11401 ggagttgtat cgcgatgccg agcgggcggg cgtacgcgac aagggcggcg tggactgtag
    11461 gcggcgctcc cgcgagggcg gcaccgatac gtagagggcc ctcgaacgtg tagctggtgg
    11521 ttttgtgttc gatgatctcg agagcacgtt gcaggttggc ttctgcgcaa ttcgtagtga
    11581 gcagatccag gtattgaccg taattgacgg aggtccgcat cgaatcgaac aagggcagta
    11641 cggtctccgc ctgagtcccg gttagctgag cgtggtgcag aagttcgtca gcccagacca
    11701 tcgcgagatc gccgaggagg atcgcggcgt gcaccccgaa ctcggccgag ttcgaatgtg
    11761 ccgggcgccg ctgttcgagc gcccgatgaa ctgtaggtct tccgcggcgg gtgtcgctgt
    11821 ggtcgatgat gtcgtcatgg atgaggattg cggtatggca cagttcgatc gcagctgcgc
    11881 agcggacgac gctcagcggt aggtcggggt cccccgccgc agcgagccac cccagtacgc
    11941 agagttgtgg gcgcaggcgt ttggcgccgg agccgacaaa cgcgtgcagc gcgccgatca
    12001 tttcgggtgg caggtgctgt cgctcggcga tagtcgcctt gtcggtcagg aatttatcga
    12061 gtgtgcggtc gaccatgacc cgtactcggg ccaggtcaat tgccgtagcc gcgtcaggat
    12121 ctgccgtcat tcgttgttgc ccttcgggtt tcggagcggc cgcgacgatg gctgatcagg
    12181 gacgacacga tccgcgacga tgaggaggta attcatgtga ccggcgcggt acgccgagag
    12241 gtagggctgc tcgacgccgg tggcgaggct ggactgctcc cgcaactccc agtagggaag
    12301 cgcctgctcg gtgaagtctt cgacatggat cggcgccagg ccggccgccg ccagggcctt
    12361 gaagtaggtg ctccgacgat ggacgtggca tacgtagtgc tggtcgatct gttccacgtc
    12421 tgggctggag aactcgactg cgtcgtcgcg acaccaggtg acggcgacgt accgcccgcc
    12481 gggtgtgagg actcgggaga attcgctgaa gaactcgtag aggtcgccgt acatcgtggt
    12541 ctcgttcgat atgacgcggt ggaagtgacc gtcgggaaac gtcgtggcag ccatgttctg
    12601 atagtggaat ctcactcgat ccgcgcaatg acgttgctcc gcaagttgtt cggcgaaggc
    12661 gatctggtat tgcgaaaagt tgacaccatc gatagcgcag ccgtaccggt catggatcat
    12721 gaagctggtg ccgccgcggc ccgatcccgc atccatcacg caatgttcgg ggccgatgtc
    12781 gccgagaacg tcgagaatca gtgatacctg atcggattcg aggcggtgca gctctgcaat
    12841 catcttctgc tcgcgttgct gcccctcacc gagcaggaca gccgggtcat agtcgccata
    12901 tccaaaatga tggtggtaca gtccatccaa ttcgcccagc agtaggttga catcgtcatg
    12961 ctgcttgcta tcccagtgct gccgcagctc cttttcgtat ggggtgcggg cgatgttggt
    13021 ggagaacgtc gcatcggtgg tcattgtcag cctccaatag tgttgatgtt caacggttct
    13081 ggcactggtg agtctgagct cgtgcatcag tggtctctgc tcagaatcag atcggcaagc
    13141 gtcaggagat ctgctgcggc gctggtttcg ggatcggcag cgagcaatga cttttcggct
    13201 tcgatgcgag atcggcgcgc ggcgacctcc gcccattgtt tgccgccggc atcgacgatc
    13261 aattgggcga gacgcgcgag ttcgtcgccg gcgaacggct cggtatcggc gtaccgctgt
    13321 gagaggcgtc gtccggctac cgtgtcggag ttcaacgcgg caactacagg tagcgacttc
    13381 tttcggcgaa tcagatctgc gtagagcggt ttgcctgtcg aatccgggtc gccgaacacc
    13441 cccagcaggt cgtcgaccag ttggaaggct cggccgatgt gcagcccgaa tgctgccagg
    13501 catgtggcgc ggctggcgtc cgcgtgcgct gcccatgcgc ccagagcgca ggatgcgctg
    13561 atgagtgtag cggtcttaca ctccgacatt cgtatgcatt cgtccaggtc gacggagttg
    13621 cgttgttcga aggcaagatc ggcggattgg ccctcacaca atccgcgaag cgcttgcgcg
    13681 agtatgtcta ctgcagcgac gtcgtgctgg gcgagcgttt cgagggcact ggcgaggaac
    13741 atgtcaccgg tgaggattgc ggggccgact ccgaactggg cccaggcggt catgcggtgg
    13801 cggcgggttc ggtcaccgtc catcacatcg tcgtgcagtt gggtgaaatc atgtatcagc
    13861 tcgactgaga ctgccgccgc gactactcga tctttgtgcc gttcgatggt gccgtccgcc
    13921 agcgccgcgg tcgacgtcag agtgagggct gggcgtatcg ctttgccgga gctggtcgtt
    13981 gggcggccgg cggcgtccca ccacccgatg tgatagccac ctatgtggct tacctccgcg
    14041 ggcaagtgtc ggacgacggc gcgatactcc ggttcgatga tcctgcgcgc gtcttccaat
    14101 atcgttgcgc cctcacgccg ttcggcatcg cgggctaaag tcatccttct caccttcttt
    14161 gatcgcgcgg tgtgacggag ccgctgaggc gaagcgagcg aagtcgcgga gtttgggcga
    14221 gctgatgtag tgattgttcc ccgccgcaaa agatcggtgc caagtttctg acggtgcttc
    14281 caattctgct tttggcaggc aagcttcggc agtttttgtg tgcgaggcgg agggcgttat
    14341 gggagatcgg ctgtctgcgt tgttcgtcct cgcatctcca agtctcgtgc tctccaaatc
    14401 tgtgcttctt ccggcatggt cttagttggg ttgagccgac gaagggtgtc ggctactgga
    14461 atgagaccga tgtgtttaag tcgaggggtt tactatttgc tcgatatgcc gaaagggcca
    14521 cgaggccgtc accggcagca ttgccgctcg gtagaccacg atatggtgaa atttggttcg
    14581 tgtagaaaaa gagattgccg tatccagcat gccggtcttc aaccgcggag ggttcgaccg
    14641 ggccaaccgt gctaccgggc acggtgaaat gccattcgat tagaagatcc gttgaactcg
    14701 acctccttgt gcatcaatcc tggttgtgta ctgtcaaccg accagttgct acttgactta
    14761 tcaagaaaat aaattgcggc gcctgccggg cgtttggtgg tacaatacag gctctttgct
    14821 tggggttgtg aggatgaccg ctgataaagt tccggcgtgt ttacttagag caaccgtcct
    14881 aatgatgatg catagctggg tctgcggcga gtttctcgga ttggtgcgcc ccgccggccc
    14941 gccatgctat tttcctgcaa catccaagtc gggtttggat gaccgatcac cgaaggatct
    15001 ggatcgatat tggtactctc attaggactt ccaggttgtt accgcgtctt gtgtttcgtt
    15061 atatttgttt gaagatcgca aatctcgcgt tttcataatg tatggggtgg ctgtctcgcc
    15121 ctgcatgggg tgaagccttg cccgatggag gggctgcgct accggcggga tcggcagtgt
    15181 aatcggaaac tggtggagga acaatgcagt cgcagcgatc ggatcatcca gccggcggtc
    15241 tttcaattgg ctctagaatc gagttcaggc ggcgccagtg cggtctgtcg agacgtgtgg
    15301 tggcaaatct cgtcggtcgt agcgaagaat ggcttcggct ggttgaaata ggtaggcaat
    15361 ccctggacag cgtgcgactc atagtccgcc tcgcggatgt tcttcggatc gagaatatcg
    15421 gcgagttgat cgagtggccg acgcatcata cgcttactcg cccggacgac gggcgtaaaa
    15481 tagtgtcttc ttacgcgcag gcactccttt ctggagatcc gcccccgtcg agtggtgatg
    15541 tatctctgaa ttccctgaat gcagatcttt cgaggtgtat tgaaatatgg gagtcgtctg
    15601 caaagcctta cactctgacg gttgagatac ttccgtcgtt gatcgctgga agtaatcatc
    15661 tctattggat gactcatgac ccttccgttg gtcaagtatc tgttcgtgca catcagctgg
    15721 cctgcatgct actaagtaga cttggcagct ttacgatagc cgtgattgcc gcagagcggt
    15781 gtgtgaatgt tgcgaagtcg gttggcgagc cgattcttgt cgctaccagc agcttgcatc
    15841 gcgcgagtgc gatgcttgca ctcggtcatt ctctgcaaag tatttatctt tcgcattcgg
    15901 ctaataagcc ttatacggta gatttcaggg agatggctat agagggttct cgtctacttg
    15961 tcgcagcgac agctgctgca ggtaaaaacg atgtccgtgc tgcggacgaa tgcattgatc
    16021 gggcaatagg tatcgcgaat aatttgagag tggagtctag ggtgggggag ttcaacttcg
    16081 gtatgacagc aattggattg actcggatga agattgcatt actacgttca gaaatcgccg
    16141 aaataccccg gatcgccgct ctcatggaaa tcccggagtc gtatcccccg gcctgtatat
    16201 ctgagtttca tattatttta gcctatgcgt tttgtcagaa gaatgaggat gttgctgccg
    16261 catattcatt atcgcgtgcc gccgaccttt gtccggaaga gatcttcctg aatccgtgtg
    16321 ccagggaagt gattgaaatc ctgattcata ggcagaataa tctggttcga caggatataa
    16381 ctcgactgct gtcacggatc gccctatttg attaggtata ttcggcaaat ccgatccacc
    16441 tctgacgagc tagcggggaa atcgctactc ggacaacagc ttctagatcc tctcggatgt
    16501 gagaatcagc ctgcgattcc tggttcgaag gggtggctcg tgactgctac cgcgcggatt
    16561 ggctggcagc ttccgtcttt ggtgttagcg gcgacacgca agatgagatg aggcgacacc
    16621 gcggtggcgg tcaaaccgac aatccgagtg gcgtcaatcc tgtcaggcag tcgatcatct
    16681 gctctagcac gggctgccac cggttcgttt cgcgtggaag tagaacgatc gtcgatgggt
    16741 ttggttacct gtttcggggt gaagaccagc gccaattgag aggcgctgat ctcatgccac
    16801 gaccgtctcc gctggagttc cgcctgagca ctgtcgcgct cgtgcgggtc gggagaccga
    16861 tcaccaccgc cgccaccgaa ttggcagtca gtgctgcgtc cttgcacaac tgggtgtgtc
    16921 aggaccaggt cgaccgcaat gaacgccgcg gcatgagaag gtgctctaga cgggtaggcc
    16981 gacggcaatg gccctcgcaa ccatccggta ttcgccgggc gatgcgatca ccccacgcgg
    17041 aaggaagctc acctcgagcg ggatcactgc ggggtccaac accgcgatcg cccggtaggc
    17101 ccggtaagta cgcctctacc tgctaggacc gctgcacccg ggccatccac cctggtccaa
    17161 gattggtcca agaaaccaac gaggtcagag gcggaaaccg cctctgacct ggtcgggctg
    17221 acaggatttg aacctgcgac cacctgaccc ccagtcaggt gcgctaccaa gctgcgccac
    17281 agcccgtttg cgctcattgc tgcgcgctcg aagagattac ctcaggggcg ggcggtggag
    17341 ctaatcggct ggtagacggc gtggcgtggg ggttggagtg tgatggggtc gtcggattcg
    17401 ggcgattgat gacgtgttgt cggggcattc gggactcggc acggtccgtg acaggcgcgg
    17461 ggtgccggaa gcgcgaagga ggcggcggtc atgcgtcggg aacggcggct ggttgaggcg
    17521 tttgtgcagc tggcggactc cctggtggag gagtacgacc cggtggacgt ggtgcagggt
    17581 ctgctggatc gggcggtgga cctgttggag gtcgataccg cggcggtcct gttggcgcgc
    17641 gacgacggcg agttgcgggt gctggcttcc acaagtgagg cggctcgatg gctggagctg
    17701 ctacagatcc aggcgcagga cgggccgtgc ctgcagtgct atcggaccag tgaacgggtg
    17761 atcgccgagg acttggcggc ggcccaggat cgttggcccg cgttcgcgaa acaggccctg
    17821 gtggaggggt ttcggtcggt gtacgcgttg ccgatgcggt tgcgcgcgga ccgggtgggg
    17881 gccctgaatc tgttcagtta cggggagacg cggctgtcgg aggacgatct ggtggtgggg
    17941 caggcgatgg ccgatatcgc gagcatcgcg atcctgcggg cgcgtcagct cgccgaccac
    18001 aagacggtga acgggcagct gcagtcggcg ctgcagacca ggatcgtgat cgagcaggcg
    18061 aagggaatac tggccgcgca aggcgatctg gatccggaga cggcattcca cgcgttgcgg
    18121 ggctacgcgc gtcactcccg cggtcgcctg ccggatctgg cgcgggcggt ggtggagcgg
    18181 accatcgatg cgcgcgtgat cctcgcgcac ggcaaccaca gaccgggatg acccgcctgg
    18241 ttgcggtgcc cagggggtga atttccgcgc ctgcgtgcag gatcgggcac cgcgttatcg
    18301 caccacggtg ttcgctgtcg gcggcgttgt ctgactcgta gcttgccgac cttcgagcgc
    18361 ggctacgctc aggcgttgac gattgccgaa tcggaggcga ggtggagtgg tgggcgagga
    18421 ggtcggcggg cgggtttatc gcgggcgcag cgctgacgag cgggcgtccg agcgtcggcg
    18481 gcggatgctg gacgcggcgg tggagctgtt cggcggacgc ggctatcccg gcacgtccat
    18541 cggcgaattg tgcacggcgg cacgggtttc gtatcgctcc ttctatgaag agttcggtgc
    18601 gctcgaccag ttgttgatcg cggcggtgga cgagttcgac gcgcgcgcgg cggaacgggt
    18661 ggtcgcggcc ctggtcgaaa ccgacgaggc cgatttcgcg acgcgcgccg cggtgacgtt
    18721 ccgggcgttc ttggcggcca cgtgcccgag ccggaaggcg gcgcggatgt gtttcgtcga
    18781 gatcgtgcga gtcgccgaca ccgtcgagat ctggcgtagg gagcggcgca ggcgattcgc
    18841 ccggttgttc gtctcgcagg ccgagatcgc ggccgagcgc ggcgagatcg cgtcacggcc
    18901 gttcgcgttc gcggcgatcg cgaccatggg tgcggtgatc tacgcgatcc aggagtgggt
    18961 gaacgccgag ccggtgttcg ccgaattcgt cggcgccgac accgacgaac tcgccgacca
    19021 gctcgcccgg atctacctcg acgcggtggg cccgctgctg ccctgactca ggcggcgcgc
    19081 tgccgtcgat cgatcgaccg tgcccactgg gtgatgggcc ggtcgaggta gcgaaagatg
    19141 gctgccgcga gcgtgatcga gagcacgaga cagaccgcgg accaggcgag ccaaccccgg
    19201 atgtcgtagc gatgaccgct catccaggtc tgggtgacgg tcaccatgat cggatactgc
    19261 accaggtaga aggcgaacga gagatcgccg agccagacca gtggacggct cgcgttgagg
    19321 ccgcggtatc cggccgtatc gcggcagcat gcggtggcga tgacgtacgc ggcgggcagg
    19381 atgatcggca ccgaaagctt gaagttcaac ggcaccaccc aggtgagcgc gtacccggcg
    19441 gccaacagca gcaaggggtg tcggtatcga gtcgcggtga agcggccgac catgacgagt
    19501 ttggccgtga gcgcaccgat gtagaactcg agcaggcggc tgggcgggaa gttgtagctc
    19561 agccagtacg acggtgtgac ggggatggca tcctgggcga accatactgg cgcggaatgt
    19621 atctcgtgct ccggtgtcac ctcgccgggc agcaggcggg gcacgaagat gttcgtcacg
    19681 cctttcggtc cgtccgcgaa aagatagaag gcgcagtgca acgcgacgat caccaggaag
    19741 accgcgatca ggcagggcag gatctggttg tcgcggagcc ggtcgacgta cggtgcgagg
    19801 accggaaagg aaaggtagaa caggacttcc gcgaccagcg accacgaggg cacattgagc
    19861 ccgcccagtg ccgtccagcc gggcacccag gtgtggatca gcaggaggtt cggcagccag
    19921 accaccgttc tggcgagtgg caccggtgcc acgacgagca agagcaccag cgcgaggaca
    19981 tgtgtcggat agatcttcag aaacctgcgg cgcagaaagg atttggcgct gtcgcccggt
    20041 cggcggttcc agcagaggat gaaccccgac agcacgaaga agaacgtcac gcccgccgcg
    20101 ccgagctgca tcggcagcac cgcatggatg cgccggaagg tctcgctgtg ctggaacgga
    20161 tacgcgggga ggaaaaccac ggcgtgcagc gcgaacaccg ccgacgccgc ccaccagcgc
    20221 atgccggtga gggaggggag ctgggcgggt cgttgcgcgg caaggcctac gggcgcgcgg
    20281 gtctcttcga tcgtcacgcc agcccgagca tctgccgtat ccccccggcg gtcgcggcgt
    20341 caccgtgccg ggagggatgc ccggggatgc cgaataactc ggcgcgggga tcgccgattc
    20401 cgttgagcca cggctctgtt gcgcacatcc cgtgaccgcg ataggccgcc gcggtatcga
    20461 agtactcgat gccgagcgcg gccgcagcac ccgcggtggc tgcgcgcaat gccgcgagat
    20521 aggccgcgag tcctgccgcc cgcggttgcg tcaccgtgcc gaggccgaac agcccgaggc
    20581 aggccgttgt gctggtgggc tcgaagaatt cggggtagcc gaccagggcg atacgcgcgt
    20641 gcggagcgta gtagcggacg tattcgatga cccgggcgat gcgggcggca tagttctccg
    20701 gagtgatccg gctcaggtcc ggtagccggc cctgtccggc ggcatcgggc tcgcatccct
    20761 ccagcaggtt gatcgcgcag cgcagcacca cgttcaacgc gacgacgtcg ttgtcgcccc
    20821 agatgtcgtt gagcccgaac tgaagcagga cggcctcggt cccggtgccg aaggccgcgg
    20881 catcggcggc ttttcgcgcc tgctgggcga gattccagcc ggtgccggta tcgagcgcgg
    20941 ccccggcgca ggacacgtcg accatggtcg cgccggtcgt ctgtgccagc tgattgggcc
    21001 aggaccgggg gttgcggtcg cactggttcg agtgctggtc cgtccctatc gaattcgagg
    21061 cgaacgaatc gccgagcacc acgatccgtg caccgccggg tgccggcgtg gcactggcgg
    21121 tggcggcgtg cgccattgcg cacagcgtcg cggtggcggc gatgcagagg cgggcaatca
    21181 tcgagttcgg ttgcactggt tcctctcctg ctcgtggcgg ggctggagtc agtacccggg
    21241 ccgcggggcg aaacccgggt tcggaagttc cggcggtgct tgcggttccg gcggtcgcgg
    21301 tgcctcgctg accggtggcc ggtacatcgg cggcatgacc gtgctcggaa ccgggaaggt
    21361 agtggtaggc gacggtatcg gcacggtgct gggcgggtgc ggcacctcgg ttgacggcgc
    21421 ggggaccgag gtcggcgcac cacggctggt ggtcgcggca ggggtgggtg cggacgtgtc
    21481 gctcgaacaa gccgtgagca gccagctgct cgcgagcagg gtgcccgccg tcagagcggc
    21541 ggcgatgcgg ggtgcgttca tcgagaggtc ctttccggca gcgcgcccat ccccgaatgg
    21601 gctttcgcga ttaccgagtg tggagatttg ccatttagca attgataggt gaaattacca
    21661 gatatgttac aacggtgcca gaaggtagct gaaacagagt gacttgcgtc acactcgatg
    21721 tagttactgc tcaaatatgc gccttgaact gcgaggattg tcgatcctca cggtcgtgag
    21781 cgatagttgc gaagagatca cgagaacgcc gtagatctga taatctgcct tatcatttca
    21841 ttctggtcgc cgacgatccg ccggtgaccg cgagaaaatg aggtacccat gtggcgcaac
    21901 gttgctaccc atgaaccccg ctccggccgt cgacgcatga ccctggccgc cctgctctgc
    21961 gtggccgtcc tggcgtcggc cccggccctc ggacacgccg cacccgcgcc gcgggacgtg
    22021 ccgatcgcgc cgttgccggt actggtcctg cccccggagt tggacccctt ctacaaggca
    22081 ccggcgaacg tcatcgccga taccccgccg ggcggcatca tcaaggccag gatgatcacg
    22141 cccgctctgc tgtcgcttgt tccgttcaac atcgacgcgt ggcaattgct gtatcgcacc
    22201 aacgacagtc acggaaatcc gatcgcgacg gtgaccaccg tcgtcaagcc gcgtggtccc
    22261 gcaccggcgg aaggcttcaa gctgctgtcc tatcaggtcg ccgaggactc cacggcgcag
    22321 tactgcgcga tgtcgtatgt ggtgcaacag ggttcgatac ccgtcgacta tgtgaactcg
    22381 gcggaggtgt cgctggcgat cgccctgggg atctcgcagg gatgggtggt gtcgatcccg
    22441 gactatcagg ggccggggtc cgcctacggc gcggcgattc tgggtggtca ggccaccctc
    22501 gacggcatca gggcgacgca gaacttcatc cccgcgcagc tgacgccgga cgcgcgggtg
    22561 ggggtgatgg gctactcggg tggttcgatc ccgacgggct gggtcgccga gaaccacggc
    22621 gaatacgccc cggagatcaa tatcgtcggc gtcaccatgg gcggcgtcgc gatggccgac
    22681 ctacgagcgg tgctgcgctc caacaacttc aacctaggtg cgggactgat cggggccgcg
    22741 ctgcggggtt tcgcgacgga atatccggag gtgcagcacg tgctcgacac caggtacgac
    22801 tggttcggcc gcttcatgac ctccatcaag ggaatgctct gtcacacaca gggttccgcg
    22861 ttcttcccgt ggtggaacta tctggggtcc tacaccggcc ccggtgacgt gctggacatc
    22921 ccggagctga gcgccgccat caccgcgcag gaactgggca aacgcgatcc ggatgtgccg
    22981 atgtacatct atcaagccca gaacgacgag ttcatcccga gcccgggcgt agatcggttg
    23041 gtggacaagt actgccgcaa tcccgaggtc tctctcggct acacccggga gttcttcgcc
    23101 gaacacgtcg tcggtatccc gggctggctg ccgaagggct accagttcat catcgaccgg
    23161 ttgaacgacg ttccggtgaa cccgggttgc gcgatcgaca gcccgttctc cacgttcacc
    23221 gacggtgatt tcatcgcgct gctcgccgag acgtggcccg ccatcgccgg tttggtcacg
    23281 ggcctgcccg tcggcgcggg cacccacccg taaggtactc agctgtgcag ggtttggctg
    23341 gggtgctgcc cgtagacgcg cttgtattcg atcgcgaatc ggcccgaatg ggtgaagccc
    23401 cactggtacg cgacggtggt caccgtgacc tgctcgccgg ggaccgcggc gcgcagttgc
    23461 tcgtgtgccg cggccaggcg tagccggcgc agcagcgcca gtggcgtggt gtcgaggtgc
    23521 ttgcggaagg ccaactgcag cgcgcgcacg gagacgaacg cggccatcgc gatatcggcg
    23581 acggcgatgt cctcggcgag gtgcgtctcg atgtaggcga cggcgcgtcg caccacgtcc
    23641 gggtgggcgt cgcgccggtc tgtcgcggtc ggatctgtga cgaccgtcgt gggcagcgtg
    23701 tccagcacgg tcgcggccag atagtcggtg agcgtggccg cgacgagctt gctcggggga
    23761 gcggcggagt ccgcggcgac ctcctgcaaa tgttcgatcg cgcgattcag ccgacgggcc
    23821 gccgccgcac tggtgggctt gtggccggtg aaccggacgg gcttgccgag tggaccgcac
    23881 acccgggaca gcagcgccgg gtcgaacatc gtgatgctgt agcgggcggt gcggatcgtc
    23941 ccgcggtacg gcaggtccgg cggggtcagc aggccgacgt cgcccgggcg gaacacatcc
    24001 gtgcccacgt cgcgataggt ttcctcgatc gcgccggtct gcaccgcgca caggcacacc
    24061 cgctccagcg gatcggcgtc gtagctcatg tcgaacccga gatccagctg atccaggctc
    24121 acggcgccga gcatgtcgcg ccgg
//
