LOCUS       NC_018681              13439 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2891466
            Orig. end                         :: 2904905
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13439
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="13"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..13439
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13439
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8439](+)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8439
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     misc_feature    complement(9..23)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    13..28
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.74"
                     /tool="antismash"
     misc_feature    complement(15..29)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(16..31)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.01"
                     /tool="antismash"
     misc_feature    19..34
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.13"
                     /tool="antismash"
     misc_feature    complement(21..34)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.12"
                     /tool="antismash"
     misc_feature    21..35
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    22..35
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.41"
                     /tool="antismash"
     misc_feature    complement(22..37)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.17"
                     /tool="antismash"
     gene            54..1661
                     /locus_tag="O3I_RS13055"
                     /old_locus_tag="O3I_012885"
     CDS             54..1661
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007320019.1"
                     /locus_tag="O3I_RS13055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012885"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_041562590.1"
                     /transl_table=11
                     /translation="MALFRIGMCAAATAFVVGLTACSAPGEKSSDPDQFVVIDTEELGD
                     FSPLLGAGKNGESKIFESLYRIEEGVTDRIPAAVPVLAVGAPEPVGGDLSRWRVHTRTG
                     VRFSDGTTFGPEDVVATYNSLIDPAFAAPIAADYDFLKRAVQTGPDTVEFELSGAYADF
                     DHRLFLAIAPSEAFATPGPADRAELNRHPIGTGPYVLTESRPDQIILTARDDYWGERAQ
                     VRKFVVRRSDDDNARASQLRDGADGTVLPPELAPAAAKDGYRVVSAVADDWRAITLPTG
                     NPVAGDPAVRKALNFAVDRKAMVEHILGGHGAPMSTLMGPVYGENYDPAQDFGFDRGEA
                     ARLLDAAGWRLGADGIRERDGRRASFEIAYYPTEVLRRDLTMAVVSDAKKVGIEITPVA
                     VDKKKMTPEYLAQTPFMLGGGGQPYTVDSQLYTKLHSRYAAPGVGSKWDNASDYVNPKI
                     DQLLDAARGETNGQRRAELYRQLQAEYHSDPAMLALVSTNHVYVLRDNGWRVTPTALEP
                     HSHGVAWGPWYGLARWTR"
     gene            1661..2635
                     /locus_tag="O3I_RS13060"
                     /old_locus_tag="O3I_012890"
     CDS             1661..2635
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005516889.1"
                     /locus_tag="O3I_RS13060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012890"
                     /product="ABC transporter permease"
                     /protein_id="WP_141692347.1"
                     /transl_table=11
                     /translation="MGGRAGRLIVRRLIVAVPLAGAVSLAVFALAAASPFDPLDAYLGA
                     HGDGFDEAQRAALRERLGLDRSWFDAWWSWLGDLMRGELGTSRSYRQPVAEVLAERLPW
                     SVLLGVLGGAVALVLAAALGAWAGLRRDGFADRIISASAVVLQSVPPFVLTLGAVLVFA
                     TTLRWFPASGLTDPGGGVGVGSTARHLVLPAVLLGVTQLPWLVLGLRETVANSLDSDAV
                     TGARARGLPWRVIAFRHVLPVSVAPFFALCGARLPELVVGATVIETVFSWPGVGAATVT
                     AARALDFPLLAALTLLVTAVVLLGNLAADAIGVAIDPRIDADG"
     gene            2628..3485
                     /locus_tag="O3I_RS13065"
                     /old_locus_tag="O3I_012895"
     CDS             2628..3485
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005243360.1"
                     /locus_tag="O3I_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012895"
                     /product="ABC transporter permease"
                     /protein_id="WP_014983395.1"
                     /transl_table=11
                     /translation="MDELLTARRSSRKQWRATVLVLAVGVLVLAVLYAGLVPLLRPVDN
                     ALVDFSISRRPPGLDFPFGTDSAGRDVFVRVAEGMRVSLLIATAAALGSALLGLLVGVS
                     AGAFGGWWDRIAMRAVDTMNSLPSLLLTLLVVAMYRGSVLAIVVALVLTHWTSVARVVR
                     GEVLALRHAEFVQAARLRGLPGWRIVRRHFIPPALGQALVGVVLLIPHAIWHESTLSFL
                     GVGLPPHRASLGTLLSDAQASILLGDWWLLVFPAGVLVLVALAVSVVGRHWQRSGQLRH
                     EVSA"
     misc_feature    3378..3380
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3482..4318
                     /locus_tag="O3I_RS13070"
                     /old_locus_tag="O3I_012900"
     CDS             3482..4318
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="O3I_RS13070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012900"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_014983396.1"
                     /transl_table=11
                     /translation="MTGATLTLQRVSVRIPLGPGRIVHAVTEADLVVARGTVHGLIGES
                     GSGKSMLSATVTGLLPKRARMTGTVALEADGRTYSAADIRQARGRTVAWVPQSAMTYFT
                     PVRRLGPQLAETIRYLGTAHEPGDLLHRVGLTADVLRRYPHELSGGMAQRAALAFALAG
                     DPALIIADEPTSALDAARAAAILGLLGEFAAAGGSVLLVTHDLTALRTAKICTDISVMY
                     ASRIVETGSAERILTAPAHPYPKDLLAALPENGLHPLPHRTPELVNLPADFRYGAT"
     gene            4315..5004
                     /locus_tag="O3I_RS13075"
                     /old_locus_tag="O3I_012905"
     CDS             4315..5004
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014319433.1"
                     /locus_tag="O3I_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012905"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_051066590.1"
                     /transl_table=11
                     /translation="MTRRFLAAEAVSVRLGGRPVLDRISLELARGEVVGLTGPSGSGKT
                     TLAQVLSGLRKPSGGRVVCDGSPLPRRHTGRIAMLFQSPRRSCDPRLTLRQSIAELARG
                     PVAWESVLESVGMTPDLLDRYPAQVSDGQLQRAAVARVLASEPDYLLCDEMTSMLDPAT
                     TASVARTVTALAATGVGVLFISHDIPLLSVCADRLVRLGDNLSPVSGAATSSPGPTVDS
                     TDDIGVL"
     gene            5001..5975
                     /locus_tag="O3I_RS13080"
                     /old_locus_tag="O3I_012910"
     CDS             5001..5975
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274262.1"
                     /locus_tag="O3I_RS13080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012910"
                     /product="ornithine cyclodeaminase"
                     /protein_id="WP_014983398.1"
                     /sec_met_domain="AesA (E-value: 9.9e-134, bitscore: 444.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNALHILTRTDLADIDLTPAEVIDLVEEGYLAYARGESRCPVKL
                     MMPIPKVERDAVSYSMLGYDSSLEQIGFKTSYRQGSESADKYYTTISLYDDTTGLPFAF
                     MDCQRVGAARTPATTAITAKHCAREGATKALMIGTGVQGRNTLPYLLTALPDLQELRLF
                     GTHPDGIAETLATMRRWYPDRKIELVGDVPTAVADSDIVVVASGRAAHPKVRTEWLPPG
                     GLLISVASKGVESGALRAADYAIATSAGQLGVTGTRLAGPDGPVIDAELPDIVAGRARG
                     RIGADDRVFAFASGMIITDIPVAHALATRAVAAGRGQRVELWS"
     gene            5972..7315
                     /locus_tag="O3I_RS13085"
                     /old_locus_tag="O3I_012915"
     CDS             5972..7315
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014942260.1"
                     /locus_tag="O3I_RS13085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012915"
                     /product="alanine racemase"
                     /protein_id="WP_041563737.1"
                     /sec_met_domain="AesB (E-value: 7.9e-182, bitscore: 603.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 6.3e-21, bitscore:
                     73.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTAPVELPGLPALEQKWQQRVRADRHLLFDIRHALGGPFHVVYP
                     EQFADNLRSFQRIFTARGVRGQVYYGKKANKAGCWLSEIADLGGAVDVASEPELVHALA
                     HGVRGRDIGVTGAAKTDALLRLAARHDCVIAIDALDELDRIAEIARQAGPVRILLRRLP
                     PNAPHSRFGLSATDLDRAIELCVRLRPRVELIGFSFHLDGYAVAPRAELADELIQLCVR
                     TRARGVPVDTISIGGGFACRYVRDDDWRTFVEQRRDDWFHAGRQFDKFYPYAQDPTGAA
                     MLDAVLATRFGARSLAENLRDNDIQLFIEPGRALLIDAGFTVFPVLGYKQNADYGITTV
                     HGLSMSVSEQWKGSEFLPDPILVPRKQIAAAVPVATCVGGASCMEYDVLTWRKVRVAQR
                     PEPGDLLLYPNTAGYQMDKNESEFHQLPLPPKVVVTEQEDRWLWRLDK"
     gene            7291..8439
                     /locus_tag="O3I_RS13090"
                     /old_locus_tag="O3I_012920"
     CDS             7291..8439
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007320012.1"
                     /locus_tag="O3I_RS13090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012920"
                     /product="cysteine synthase family protein"
                     /protein_id="WP_337587882.1"
                     /sec_met_domain="AesC (E-value: 4.1e-153, bitscore: 508.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 3.1e-57, bitscore: 193.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVAFGQVEADATTVRPVGRATVHPAGVRPMPRLRENVVRSASEL
                     IGATPLLELVRTGTGTRILLKLEQFNPTGSAKVRMAREMVLQAERSGELRPGGHIVEPT
                     SGNTGTGLALIALERGYTFTAVVDDHAAKDKLRAMKAMGAQLVSVDSGDSGGPSTVERR
                     RIADEIAARTGAYRPDQHNNPHNNAGYRDLAGELLTDLNTDVDYLVGAVGTGGSLCGTV
                     EELRRLGSRVHAIGVEPVGSIIFGGAGGSYWQTGAGSPAGFPVGGNVKYDAIDEDCRVN
                     DVDAFATARVVARRTGILVGGTGGAAIHIALRRLVHVPAASTVVVLVCDAGEKYLDTVY
                     DEDWLHARGLYDRAAQQRITRLLTAYDESVRLAADDLERARA"
     gene            8444..9847
                     /locus_tag="O3I_RS13095"
                     /old_locus_tag="O3I_012925"
     CDS             8444..9847
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013139338.1"
                     /locus_tag="O3I_RS13095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012925"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_014983401.1"
                     /transl_table=11
                     /translation="MAIREYRAIVALAAPIAGIQLAQVALTTVDLAMMGLLGIAAVAAG
                     GLALLLYNQLRTMCVGMVTGVGNMIAAAAGRGEKRTGSGRLDEQARAEIRGYVRAAAAV
                     ATVVSIVGALILVALGYALRWFGQDPAVLALARPIIWALAPGLIPMLWLNVLRQFAVGL
                     RRAGSLLRVTLLSIGVNALLNALFIFGWFGSPQLGLAGIGLSTTLVQAWTFGTYLRTVR
                     RDPVLGELLSLRVWIADRATVLRIVRMGTPISLTYGAEAAITSIATVLMGGFGPVALAA
                     SNIVNQLAYIVYQVNIGLSQGSSILVSRTVGQGDQHAVAGIARRTFALGFGFMTVVGLV
                     YVVVPGAVLAPFLGADRDDTAVVAAASTLLWFAIVQQYCKGSQNLCIGLLRGIGNTKAG
                     MQSTLIGYFVLGVPAMALFAFTLDLRGPGIWLGLCVGFGTTAILVWRRFLRGVAELTAA
                     AREPVPVTG"
     gene            10108..11652
                     /locus_tag="O3I_RS13100"
                     /old_locus_tag="O3I_012930"
     CDS             10108..11652
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018177551.1"
                     /locus_tag="O3I_RS13100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012930"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_014983402.1"
                     /transl_table=11
                     /translation="MCAAGPFSGLNRRQFLAKAAAAGAVGALASWADPIIQRAYAADPA
                     GTGGLGDIEHFVLLMQENRSFDHYFGTLSGVRGFDDPSQSWRQYGWTPGIGPTPDGFVH
                     PFRLDTTRGATLDGECINDPDHSWGGMHRAWNGGRNDGWMPMSVDSVGPANAPAAMGYY
                     LPEDIPIHTALADAFTLCDNYHCSVLGPTDPNRLYWISATIDPDGYAGGPLVRTPTLIP
                     QHVYSWRTYPENLTEAGVSWKIYNNRDVGPLSSVLLDGMLGCFTQSADPASDLARRGMA
                     PVYPNDFQADVANDTLPAVSWVIPSLLNCEHPALPAAFGAFGIVQLLDILTANPKVWEK
                     TALIISYDENGGFFDHVTPPTAPPGTPGEFLTVPLDRVEAADGTAGPIGLGYRVPALVI
                     SPYTRGGLVASETFDHTSQLRLLEARFGVDVPNLTAWRRGVTGDMTSTFDFGSAPNSAK
                     PVLPDPKPKMDAAIAQCGPNVALGTATAGVPYPVPPNAMPTQQPGTRRRPSGLIRA"
     misc_feature    11638..11640
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11701..11913)
                     /locus_tag="O3I_RS44805"
                     /old_locus_tag="O3I_012935"
     CDS             complement(11701..11913)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS44805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_012935"
                     /product="hypothetical protein"
                     /protein_id="WP_141692293.1"
                     /transl_table=11
                     /translation="MGTRNNQTGRHRLGMAGGVHCTQIPAVAEALAEHRRTWFTALISP
                     ARHSFAAMRKRSTVPSVRWVPATAS"
     misc_feature    complement(11959..11977)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.53"
                     /tool="antismash"
     misc_feature    12060..12078
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.91"
                     /tool="antismash"
     gene            12220..13419
                     /gene="coaE"
                     /locus_tag="O3I_RS13105"
                     /old_locus_tag="O3I_012940"
     CDS             12220..13419
                     /EC_number="2.7.1.24"
                     /GO_function="GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="coaE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009977350.1"
                     /locus_tag="O3I_RS13105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_012940"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_014983404.1"
                     /transl_table=11
                     /translation="MLRIGLTGGMGAGKSTVARILADRGAVIVDSDLIAREVVAPGTEG
                     LAALVDAFGSGILSADGSLDRPALAAKAFADDASRARLNSITHPLVGKRTAELIAAAAP
                     DAIVVQDIPLLVENGLAPLMNLVLVVDVPAETRLRRLVEFRGVAEADARARIAAQATDE
                     QRRAVADVLLDNSGAPADIEETVRALWDERLVPFEHNLRTGTSARRKELRLVPANPEWA
                     AQAQRLIARLWVACGQAASRIDHIGSTSVPELPAKDVIDLQITVADLAAADGLRDALGA
                     AGFPVRPEVVQDSPKPTPADPDGTDLTLWTKRYHQSADPGRLANVHVRVDGSPGQRFAL
                     AFRDWLRADAAARAEYLEVKRTGEAKAAGLDGAAAMTAYLDVKEPWFDSAYHRLAERNA
                     "
ORIGIN
        1 ggtttcactg aaaatgctaa tgaaaatcat taccagtagt ctacgatgct gacatggctt
       61 tgtttcggat cgggatgtgt gctgccgcaa cggcattcgt agtagggctg accgcatgct
      121 cggcgccggg ggaaaaatca agcgatccgg atcaattcgt ggtgatcgac accgaggaac
      181 tcggcgactt cagcccgctg ctcggcgcgg ggaagaacgg cgagtcgaag atcttcgaaa
      241 gcctgtaccg gatcgaggag ggcgtgacgg atcggatccc ggcggccgtg ccggtgctgg
      301 ccgtgggcgc gccggagccg gtcggcggcg acctgtcccg ctggcgggtg cacaccagaa
      361 ccggggtgcg tttctcggac ggcaccacgt tcgggcccga agacgttgtc gcgacctaca
      421 actcgttgat cgacccggcg ttcgccgcac cgatcgccgc ggactacgac ttcctgaaac
      481 gggcagtgca gacggggccg gataccgtcg agttcgaatt gtccggcgcc tacgccgatt
      541 tcgaccatcg actgttcctg gcgatcgcgc cgtccgaagc tttcgccacc ccgggacccg
      601 cggatcgggc cgagctgaac cggcatccga tcgggaccgg accgtacgtc ctcaccgaat
      661 cccgccctga tcaaatcatt ctcaccgccc gtgacgatta ctggggcgag cgcgcccagg
      721 tgcgaaagtt cgtggtgcgc cgcagtgacg acgacaacgc cagagcgagt caactgcgtg
      781 acggggccga cggcacggtg ctgccgccgg agctggcccc cgcggcggcc aaggacggct
      841 atcgggtcgt ttcggcggtg gccgacgatt ggcgcgccat caccctgccg accggcaatc
      901 cggtcgcggg tgaccccgcg gtccgcaagg ccttgaactt cgccgtggac cgtaaggcca
      961 tggtggagca catcctcggc gggcacggtg cgccgatgtc caccctgatg ggcccggtat
     1021 acggcgagaa ctacgacccc gcacaggatt tcggcttcga ccggggcgag gcggcgcggt
     1081 tgctggacgc agcgggttgg cggctcggtg cggacggcat ccgggaacgg gacgggcggc
     1141 gcgcaagttt cgagatcgcc tactatccga cggaagtgct gcgccgcgat ctgacgatgg
     1201 ccgtggtctc ggacgcgaag aaggtcggca tcgagatcac cccggtcgcg gtcgacaaga
     1261 agaagatgac gccggagtac ctggcgcaga cccccttcat gctcggtggc ggcggccagc
     1321 cctacacggt ggacagtcag ctctacacca aactgcattc ccgctacgcc gcaccgggtg
     1381 tcggctccaa gtgggacaac gcctcggact acgtgaaccc gaagatcgat caactgctcg
     1441 atgctgcccg cggcgagacg aacgggcagc ggcgggccga gctgtaccgg cagctccagg
     1501 ccgaatacca cagcgatccc gcgatgctcg cgctggtcag tacgaaccac gtctacgtgc
     1561 tgcgcgacaa tggctggcgg gtcacaccga ctgcgctgga accgcattcg cacggcgtcg
     1621 cgtggggtcc gtggtacggg ctcgcgcgct ggacccggtg atgggtggta gagcgggcag
     1681 gttgatcgtg cgccggctca tcgtcgcggt accgctggcc ggagcggtct cgctcgccgt
     1741 gttcgcgctc gcggcggcca gtccgttcga cccgctggac gcctacctcg gcgcgcacgg
     1801 ggacggcttc gacgaggcgc agcgcgcggc gctgcgcgag cgactcgggt tggaccgcag
     1861 ctggttcgac gcgtggtggt cctggctcgg tgacctgatg aggggcgagc tgggcacctc
     1921 ccggtcctac cggcagcccg tcgccgaggt gctcgccgag cggctgccct ggagtgtgct
     1981 gctcggcgtg ctcggcggcg cggtggcgct ggtgctcgcc gccgcactcg gcgcgtgggc
     2041 cgggctgcgc cgcgacggct ttgccgatcg gatcatcagc gcgagtgccg ttgtgttgca
     2101 gtccgttccg ccgttcgtgc tgacgctcgg cgcggtgctg gtcttcgcga ccaccctgcg
     2161 ctggtttccg gcctcgggtc tgaccgaccc cggtggcggc gtcggtgtcg gatcgacggc
     2221 ccggcatctc gtgctgcccg cagtgctgct cggggtgacg caactgccct ggctggtgct
     2281 cggcctgcgg gagaccgtgg cgaacagcct cgacagcgac gccgtcaccg gggctagagc
     2341 acggggattg ccgtggcggg tcatcgcttt ccggcatgtg ctcccggtgt cggtcgcgcc
     2401 gttcttcgcg ctgtgcggcg ccaggctgcc ggagctggtg gtcggcgcca cggtgatcga
     2461 gacggtgttc agctggccgg gtgtgggcgc ggcgaccgtg accgccgccc gcgcactgga
     2521 tttcccgttg ctcgccgcgc tgacgctgct cgtcacggcg gtggtgctgc tcggcaatct
     2581 ggccgccgat gcgatcggcg tggccatcga tccgcggatc gacgccgatg gatgagctgc
     2641 tgaccgcccg gcggtcgtcc cggaaacagt ggcgtgcaac ggttctcgtg ctcgcggtgg
     2701 gcgtgctggt gctcgcggtg ctgtacgccg ggctggtgcc gctgctgcgg ccggtcgaca
     2761 acgcgctggt cgatttctcg atcagcaggc ggccgcccgg tctggacttc ccgttcggca
     2821 ccgacagcgc cgggcgtgac gtgttcgtcc gcgtcgccga gggcatgcgc gtctcgctgc
     2881 tgatcgcgac ggccgccgcg ctcggatcgg cgctcctcgg cctgctggtc ggggtgagcg
     2941 cgggggcgtt cggcggctgg tgggatcgga tcgcgatgcg cgcggtggac acgatgaact
     3001 cgctgccgag cctgctgctc actctgctgg tcgtggccat gtatcgcggc tcggtgctcg
     3061 ccatcgtcgt cgcgctcgtg ctcacccatt ggacctcggt ggccagggtg gtgcggggtg
     3121 aggtgctggc gctgcggcac gccgaattcg tgcaggcggc ccgattgcgc ggcctgcccg
     3181 gatggcgcat cgtccggcgg cacttcatcc cgcccgccct cggtcaggcg ctggtcggcg
     3241 tcgtgctgct gatcccacac gcgatctggc acgagtcgac gctgtcgttc ctgggcgtcg
     3301 gcctgccgcc gcaccgggcc tcgctcggca cgctgctctc ggacgcgcag gcgtcgattc
     3361 tgctggggga ctggtggtta ctggtctttc cggccggggt gctggtgctc gtcgcgctgg
     3421 cggtatcggt ggtcggcagg cattggcagc gcagcggtca actgcgccac gaggtgtcgg
     3481 catgacgggg gcgacgttga cgttgcagcg tgtgtctgtg cgaatcccgc tgggtcccgg
     3541 ccgcatcgtg cacgcggtca ccgaggcgga cctggtcgtc gcgcgcggca cggtacacgg
     3601 attgatcggc gaatcgggct ccgggaaatc catgctgtcc gcgaccgtca ccggattgct
     3661 gccgaaacga gcccgcatga ccggcaccgt cgcgctcgag gccgacggca ggacctactc
     3721 cgcagcggat atccggcagg cacggggacg caccgtggcg tgggtcccgc agtcggcgat
     3781 gacgtacttc acgccggtcc ggcggctggg accgcaactg gccgaaacga tccggtacct
     3841 gggcaccgcg cacgagccgg gcgacctgct gcaccgggtc ggtttgaccg cggacgtgct
     3901 gcgccggtac ccgcacgagc tctcgggcgg tatggcgcag cgggcggcgc tggcgttcgc
     3961 actggccggt gatcccgcgc tcatcatcgc cgacgaaccg acctcggcgc tcgatgccgc
     4021 gcgggcggcc gcgatcctgg gcctgctcgg cgaattcgcc gcggcgggcg gcagcgtact
     4081 gctcgtcacg cacgacctga cggccctgcg caccgcgaag atctgcacgg acatttcggt
     4141 gatgtacgcg tcccggatcg tcgaaaccgg cagtgccgag cggatcctca ccgcgcctgc
     4201 gcacccgtac ccgaaggatc tgctggccgc gctgcccgag aacggtttgc acccactgcc
     4261 gcatcgcaca ccggaactgg tgaacctgcc cgcggacttc cgctatggag cgacatgacc
     4321 agaagatttc ttgcggcaga agctgtttcg gtgcgactgg gcggtcgccc ggtgctcgac
     4381 cggatctcgc tcgagctggc tcgtggtgag gtcgtggggt tgaccgggcc ctccgggagc
     4441 ggcaaaacga cactcgcgca ggtactgtcg ggcctccgca aacccagcgg cggccgggtc
     4501 gtctgtgacg ggagtccgtt gccccggcgg cacaccggac gcatcgcgat gctgttccag
     4561 tcgccgcggc ggtcctgcga tccgcgcctg accttgcgcc aatccatcgc cgaactcgcg
     4621 cgcgggccgg tggcctggga gagcgtgctc gaatccgtcg gcatgacacc ggatctgctc
     4681 gaccggtatc cggcgcaggt ttccgacggt cagttgcaac gggccgccgt cgcgcgggtg
     4741 ctcgcgtccg agcccgacta cctgctgtgc gacgagatga cctcgatgct cgacccggct
     4801 accaccgcct cggtcgcccg caccgtgacc gccttggcgg ccacgggtgt cggcgtgctc
     4861 ttcatcagtc acgacatccc cctgttgagc gtgtgcgcgg atcggctggt gcgcttgggg
     4921 gacaaccttt ctcccgtgtc cggggcggca acgtcgtcgc ccggaccgac cgttgattcg
     4981 accgacgaca tcggagttct atgagcaacg cactgcatat cctcacccgc accgatctgg
     5041 ccgatatcga tctgacgccc gccgaggtca tcgatctggt cgaggagggt tatctggcgt
     5101 acgcgcgcgg cgaatcccgg tgcccggtca agctgatgat gccgattcct aaggtggagc
     5161 gggacgcggt gtcgtattcg atgctgggct acgacagttc gctggaacag atcggtttca
     5221 agacgtccta ccgacagggc agtgaaagcg cggacaagta ctacaccacg atcagcctgt
     5281 acgacgacac cacagggctg ccgttcgcct tcatggactg ccagcgggtc ggtgccgccc
     5341 ggaccccggc gacgacggcc atcaccgcga aacactgtgc ccgcgagggc gcgacgaagg
     5401 ccctgatgat cggcaccggg gtacaggggc gcaacacctt gccgtacctg ctcaccgcgc
     5461 taccggacct tcaggagttg cgcctgttcg gtacccatcc ggacggtatc gcggaaaccc
     5521 ttgccaccat gcggcgttgg tatccggacc ggaagatcga gctggtcggc gacgtaccca
     5581 ccgcggtcgc cgattcggat atcgtcgtcg tcgcctccgg gcgggcagcg catccgaagg
     5641 tacgcaccga gtggttgccg ccgggcggtt tgctgatctc ggtggccagc aaaggcgtcg
     5701 agagcggcgc gctgcgcgcg gcggactacg cgatcgcgac cagtgcgggg cagctgggcg
     5761 tcaccggcac ccggctggcc gggcccgacg gaccggtgat cgacgccgaa cttccggaca
     5821 tcgtggccgg acgggcacgc gggcggatcg gcgcggacga tcgggtgttc gccttcgcca
     5881 gcggcatgat catcaccgat atcccggtcg cgcacgcgct ggcgacccgg gcggtggcgg
     5941 cgggacgcgg acagcgggtg gaactgtggt cgtgaacacc gcaccggtcg aactccccgg
     6001 tctgcctgcg ctggaacaga agtggcagca gcgggtgcgc gcggaccggc acctgctctt
     6061 cgatatccgg cacgcgctgg gtggcccgtt ccacgtcgtc tacccggagc agttcgccga
     6121 caacctcagg tcgttccagc ggatcttcac cgcacgcggt gtgcgcggcc aggtctatta
     6181 cggcaagaag gccaacaagg ccggctgctg gctgtccgag atcgccgatc tgggcggggc
     6241 ggtcgacgtg gcgagcgaac cggaactggt gcacgcgctg gcgcacggtg tccgcgggcg
     6301 cgacatcggg gtgacgggtg ccgcgaaaac cgatgcgctg ctgcgcctgg ccgcccgcca
     6361 cgactgcgtg atcgccatcg acgcgctcga cgaactggat cggatcgccg agatcgcccg
     6421 gcaggccggg ccggtacgga tcttgttgcg gcggctgccg cccaacgccc cgcacagccg
     6481 gttcggtttg tccgcaaccg atctcgatcg cgcgatcgag ttgtgcgtgc ggctgcggcc
     6541 gcgggtggaa ctgatcgggt tctcgttcca tttggacggc tacgcggtcg cgccacgcgc
     6601 cgagctcgcc gacgagctga tccagctgtg cgtgcggacg cgggcgcggg gagtgcccgt
     6661 cgacacgatc tcgatcgggg gcggattcgc ctgccggtat gtgcgcgacg acgattggcg
     6721 taccttcgtc gaacagcgcc gcgacgactg gttccacgcc ggaagacaat tcgacaagtt
     6781 ctatccctac gcccaggacc cgaccggcgc cgccatgctc gacgccgtgc tggccacccg
     6841 gttcggtgcc cgatccctgg cggagaactt gcgggacaac gatattcagc tcttcatcga
     6901 gccgggccgc gccttgctga tcgatgcggg attcacggtg ttcccggtgc tcggttacaa
     6961 acagaacgcc gattacggca tcacgaccgt gcatgggctc agcatgagcg tctccgagca
     7021 gtggaagggc agcgagttcc tgcccgaccc gatcctggtg ccgcgcaagc agatcgccgc
     7081 cgccgtaccg gtcgccacct gtgtcggcgg cgccagctgc atggagtacg acgtgctcac
     7141 ctggcgcaag gtccgtgtgg cgcagcgacc cgaacccggt gacctgctgt tgtatccgaa
     7201 cacggcgggc tatcagatgg acaagaacga gagcgagttc catcagctcc cgttgccgcc
     7261 caaggttgtc gtcaccgaac aggaggaccg gtggttgtgg cgtttggaca agtagaagcg
     7321 gacgcgacga cggtgcgtcc ggtcggccgc gccaccgtgc atccggccgg cgtgcggccg
     7381 atgccccggc tccgggagaa cgtcgtccgc agcgcgtccg agctcatcgg cgcgaccccg
     7441 ctgctcgaac tggtgcgcac cggcaccggc acccggatcc tgttgaagct ggagcagttc
     7501 aacccgaccg gctcggcgaa ggtgcgcatg gcgcgcgaaa tggtgttgca ggccgaacgc
     7561 agtggcgaac tgcggccggg cgggcacatc gtcgaaccca cgtccggcaa caccggtacc
     7621 gggctcgccc tgatcgcgct ggaacgcggc tacacgttca ccgcggtggt cgacgaccac
     7681 gccgcgaagg acaagctgcg tgcgatgaaa gcgatgggcg cgcagctggt ctcggtggac
     7741 agcggtgaca gcggtggccc gagcacggtc gagcgcaggc ggatcgccga cgagatcgcc
     7801 gcgcgcaccg gtgcgtatcg ccccgatcag cacaacaatc cgcataacaa cgcgggttat
     7861 cgggacctgg ccggcgaact gctcaccgat ctcaacaccg atgtcgacta tctcgtcggt
     7921 gcggtcggca ccggcggatc actctgcggc acagtcgaag agctgcgcag gctcggctcc
     7981 cgggtgcacg cgatcggggt cgagcccgtc ggttcgatca tcttcggtgg cgcgggcggc
     8041 agctattggc agaccggcgc gggcagcccc gccgggttcc cggtcggcgg caacgtgaaa
     8101 tacgacgcga tcgacgagga ctgccgggtg aacgatgtcg atgcgttcgc caccgcgcgc
     8161 gtggtggcgc ggcgtaccgg catcctggtg ggcggcaccg gtggcgcggc gatccacatc
     8221 gcactgcgcc gcctggtgca cgtccccgcg gcgagcaccg tggtggtgct ggtgtgcgac
     8281 gcgggcgaga agtacctcga caccgtctac gacgaggact ggctgcacgc gcgcgggctg
     8341 tacgaccgcg cggcgcaaca gcggatcacg cgtctgctca cggcctatga cgaatcggta
     8401 cggttggcgg ccgacgacct ggaacgggcg agggcgtaaa gctatggcaa ttcgggagta
     8461 tcgcgccatc gtcgcgctgg ctgcgccgat cgcgggcatc cagctcgccc aggtggcact
     8521 gaccacggtc gatctggcga tgatgggact gctcggcatc gcggccgtcg cggcgggcgg
     8581 gctcgcgctg ctgctgtaca accagctgcg cacgatgtgc gtcggcatgg tcaccggtgt
     8641 cgggaacatg atcgccgcgg ccgccgggcg gggcgaaaag cgcaccggca gtggccgact
     8701 cgatgaacag gcacgcgccg agatccgcgg gtacgtgcgc gccgccgccg cggtggccac
     8761 cgtggtgtcg atcgtgggcg cgctgatcct cgtcgcgctc ggctacgcgc tgcgctggtt
     8821 cgggcaggac ccggcggtgc tcgcgctggc gcggccgatc atctgggcgc tcgcgccggg
     8881 actgattccg atgctgtggc tgaatgtgct gcggcagttc gccgtcgggc tgcgccgcgc
     8941 gggctcgctg ctgcgggtga cgctgctgtc gatcggcgtg aacgcgctgt tgaacgcgct
     9001 gttcatcttc ggctggttcg gtagtccgca gctgggcctg gccggtatcg gtctgtccac
     9061 gacgctggtg caggcctgga ccttcggcac ctacctgcgc accgtccggc gcgatcccgt
     9121 actaggcgaa ctgctttcgc tgcgcgtgtg gatcgccgac cgcgccacgg tgctgcggat
     9181 cgtccggatg ggcacgccca tctcgctcac ctacggcgcg gaagcggcga tcacgtccat
     9241 cgcgacggtg ctgatgggtg gtttcgggcc ggtggcgctg gccgcgagca atatcgtcaa
     9301 ccagctggct tacatcgttt accaggtgaa catcggcctc tcgcagggct cctcgatcct
     9361 ggtgagtcgc accgtcgggc aaggggatca gcacgcggtc gccggcatcg cccggcgcac
     9421 tttcgcgctc ggcttcggct tcatgacggt ggtgggactg gtgtacgtgg tggtcccggg
     9481 tgcggtgctc gcgccgttcc tcggcgcgga ccgcgacgac accgcggtgg tcgcagcggc
     9541 gtcgacgctg ctgtggttcg cgatcgtcca gcagtactgc aagggttcgc agaatctgtg
     9601 catcggcctg ctgcgcggca tcggaaacac caaggcgggc atgcagagca cattgatcgg
     9661 ctacttcgtg ctcggtgtgc ccgcgatggc gctgttcgcg ttcacgctcg atttgcgcgg
     9721 gccagggatc tggctgggct tgtgcgtggg cttcggtacc accgcgatcc tggtgtggcg
     9781 caggtttctg cgcggggtcg ccgagttgac cgcggccgca cgggaacccg tgcccgtcac
     9841 cggatgaacg ggaggaatac ggcaaagcgt atgaaaccgg ctgtaccgct gggattctcg
     9901 ggtacgttgc gttgagttca tcgacagtcc ggcaattcgg gcaatcgacg gcaattgttc
     9961 agcatcgatc ggtggtgaac gtggtccaga tcaccggatc ggcagcacct gttgatcttt
    10021 ctctgcggcg tcaccgcacc tcgggtaggg tcggcgcgga tcgcgaaatt ctgctcgaca
    10081 gccctggcgg aaaggtcggc cgacacgatg tgcgcagcgg ggccgttcag cggactcaac
    10141 cgcagacaat tcctagcgaa ggcggccgcg gccggtgcgg tgggcgcgtt ggcctcctgg
    10201 gccgacccga tcatccagcg ggcctacgcc gccgacccgg cgggcacggg cgggctcggc
    10261 gatatcgagc atttcgtgct gctgatgcag gagaaccgtt ccttcgacca ctatttcggc
    10321 acattgtcgg gcgtccgcgg cttcgacgac ccgtcgcaat cctggcggca gtacgggtgg
    10381 acgcccggaa tcggccccac gcccgacggt ttcgtgcatc cgttccggct cgacaccacc
    10441 cgcggcgcca cgctggacgg cgaatgcatc aacgatccgg atcattcctg gggcggcatg
    10501 catcgcgcct ggaacggcgg ccgcaacgac gggtggatgc cgatgtcggt ggacagcgtc
    10561 ggcccggcga acgcacccgc cgcgatgggt tactacctgc cggaagacat tccgatccat
    10621 accgcgctcg ccgacgcctt cacgctgtgt gacaactacc actgctcggt gctcggaccc
    10681 accgatccga atcggctgta ctggatcagc gcgactatcg atccggacgg ctacgcgggc
    10741 ggtccgctgg tacggacgcc gacgctcatc ccgcagcacg tgtacagctg gcgcacctac
    10801 ccggagaacc tcaccgaggc cggggtgagc tggaagatct acaacaaccg cgatgtcggc
    10861 ccgctgtcct cggtgctcct ggacggcatg ctcggctgct ttacccaatc tgccgaccct
    10921 gcttcggatt tggcgcgccg cgggatggcg ccggtgtacc ccaacgattt tcaggccgac
    10981 gtcgccaacg acacgctgcc cgcggtgtcc tgggtgatcc cctcgctgct caactgtgaa
    11041 catccggcgc tgcctgcggc tttcggcgcc ttcggcattg tgcagctgct cgacatcctc
    11101 accgccaacc cgaaggtgtg ggagaagacc gcgctgatca tcagctacga cgagaacggc
    11161 ggcttcttcg atcacgtcac cccgccgacc gcgccgccgg gcactccggg cgagttcctc
    11221 acggtgccgc tcgaccgcgt cgaggcggcg gacggcacgg ccggcccgat aggtctcggc
    11281 tatcgtgttc cggcactggt gatctcgcct tacacgcgtg gcggactcgt cgcgtccgag
    11341 accttcgatc acacctcgca attgcgcctg ctggaagcca gattcggcgt cgacgtgccc
    11401 aacctgacag cgtggcggcg cggcgtgacc ggcgatatga cctccacgtt cgatttcggc
    11461 tccgcgccga attcggcgaa acccgtactg cccgatccga aaccgaaaat ggatgccgcg
    11521 atcgcccaat gcggcccgaa tgtcgccctg ggaacggcga ccgccggagt tccttatccg
    11581 gtgccgccga atgccatgcc gacgcaacaa cccggtaccc ggcgcaggcc gagcgggtta
    11641 attcgggcat gagagtggcc cagccctggc gggggctggg ccactgctcg aagtgtgagg
    11701 tcagctcgcg gtcgcgggca cccaccggac cgaggggacg gtggagcgtt tgcgcatggc
    11761 cgcgaaactg tgccgggccg ggctgatcaa cgcggtgaac caagtgcggc ggtgctcggc
    11821 cagcgcctcc gcgacggcgg gaatctgggt gcagtgcacg ccgcccgcca tacccaggcg
    11881 gtggcgaccc gtctggttgt ttctggtgcc caatggtgtt cctttgcttg ctggtgctgg
    11941 cgcctggatc gccacggcga agattagccg aacgaaagtg ccgcgcagag tattttgcgc
    12001 aagtaattgg ctcggcgtgt cggaaagttg tcgccgcgtg acccggttcg accggaattg
    12061 ttgcgaatcg gtctcggcct cgtcacggat cgaacaaatg cggcgagggc aggtggaaag
    12121 tcagccccca gtgggtaatc gggctgattg tgtcccgtcg gcggccgcgg gcacgggtgg
    12181 ggcgcggcgc gtgtgaacgc cggatgtaag actggtcgaa tgttgcggat cggcctcacc
    12241 ggaggcatgg gagcgggcaa gtcgacggtg gcgcggattc ttgccgaccg tggggcggtg
    12301 atcgtcgatt ccgatctgat cgccagggag gtcgtcgcgc ctggcaccga aggcctcgcg
    12361 gcccttgtgg acgcgttcgg ctccggcatc ctctcggccg acggcagcct ggaccgcccc
    12421 gccctcgccg ccaaggcttt cgccgacgac gcgtcccggg cgcggctgaa ttccattacg
    12481 catccgctgg tgggtaaacg cactgcggaa ttgattgccg ccgcggcgcc ggacgccatt
    12541 gtggtgcagg atattccgct gctggttgaa aacggtctcg ccccgttgat gaatctcgtg
    12601 ctggtcgtcg acgtgcccgc ggaaactcgg ctgcgccgat tggtagaatt ccgcggtgtc
    12661 gccgaagcag acgcgcgggc tcgaattgcg gcacaggcca ccgacgagca gcggcgtgcg
    12721 gtagccgatg tgctgctgga caacagtggc gcgccggcgg atatcgagga gacggtccgc
    12781 gcgctgtggg acgagcggct ggtgccgttc gaacacaacc tgcgtaccgg gacctccgcc
    12841 cggcgcaagg agttgcggct cgtaccggcg aacccggagt gggcggcgca ggcgcagcgc
    12901 ctgatcgcgc ggctgtgggt ggcctgcggc caggccgcct cgcggatcga tcacatcggc
    12961 tcgacctcgg tgccggagct gcccgcgaag gacgtgatcg atctccagat caccgtcgcc
    13021 gacctggcgg cggcggatgg gctgcgagat gcgttggggg cggcgggctt tccggtgcgg
    13081 ccggaggtcg tccaggacag tccgaaaccg acgcccgcgg atccggacgg caccgatctc
    13141 accttgtgga ccaagcgata ccaccagagc gccgaccccg gccgcctcgc caacgtgcat
    13201 gtgcgcgtgg acggttcgcc ggggcagcgg ttcgcactcg ccttccgcga ctggttgcgc
    13261 gccgatgccg cagcgcgcgc cgaatacctc gaggtcaagc gcaccggcga ggcgaaggcg
    13321 gccgggctcg acggcgcggc ggcgatgact gcttatctgg acgtcaagga accctggttc
    13381 gactccgcat accaccggct cgcggaacga aacgcttagg ggcctgggcc gcaaccgat
//
