LOCUS       NC_018681              25541 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2603888
            Orig. end                         :: 2629429
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25541
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="12"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25541
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25541
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15541](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15541)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            795..2024
                     /locus_tag="O3I_RS11680"
                     /old_locus_tag="O3I_011505"
     CDS             795..2024
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011208259.1"
                     /locus_tag="O3I_RS11680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011505"
                     /product="ubiquinol-cytochrome c reductase iron-sulfur
                     subunit"
                     /protein_id="WP_081593962.1"
                     /transl_table=11
                     /translation="MTEKEPNVGRPDEGHDGVEPSNEQVTGAGAHVAKTDGHALTEPTE
                     AELDAMSRDELVKLGTERDGVDVAYRRERFPVPGTRAEKRAERAVAFWFAVSGIAAAAL
                     VGVFLFWPWEFKANKEDGHAAYSLFTPLVGITFGVSVLVIGIAVVLIRKLFIPAELSIQ
                     DRHDGPSPEVERRTLVAELSDALETSTLARRKLITRTAGAGVGVLGIGALLVFVGGMVK
                     NPWAKGDKSPLWVSGWTPDYEGETIYIRRDTGRPEDIVLVRPEDLDAGAMETVFPWKEK
                     WRGDEHATLQSLRGIRNPVMLIRLRTEDAQKAIKRKGQESFNYGDYFAYSKICTHLGCP
                     TSLFEQQTNKILCPCHQSQFLATEWGKPVFGPAARALPQLPITVNSEGFLVANGDYIEP
                     LGPAFWERRS"
     gene            2021..3643
                     /locus_tag="O3I_RS11685"
                     /old_locus_tag="O3I_011510"
     CDS             2021..3643
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007531106.1"
                     /locus_tag="O3I_RS11685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011510"
                     /product="ubiquinol-cytochrome c reductase cytochrome b
                     subunit"
                     /protein_id="WP_014983118.1"
                     /transl_table=11
                     /translation="MSPSVAAQANEADERYRAAAFMKRSINKVFPTHWSFLLGEIALYS
                     FIILLLSGVYLTLFFDPSMTEVVYNGAYQPLRGVTMSRAYESSLNITFEVRGGLFVRQV
                     HHWAALLFAASIIIHLFRIFFTGAFRKPREANWVIGCLLLILAMFEGFFGYSLPDDLLS
                     GTGLRAAFGGITMSVPIAGTWLHWLIFGGDFPGDIIIPRLYIAHVLLFPGIILALIAAH
                     VALVWYQKHTQFPGPGRTENNVVGARIVPVFAADQGAFFAFTLGIVGIMGGVFQINPIW
                     NLGPYNPSQVSAGSQPDFYMMWTDGLARLMPPWELYLGRYTVPAVFWVALIMGLVFTVL
                     IAYPWIEKRLTGDVGSHHNLLQRPRDVPVRTAIGAMAIGFYVVLTLSCVNDILALKFDI
                     SLNATTWMGRIGLLVVPPVAYFVAYRFCIGLQRSDRAVLEHGIETGVIKRLPHGEYIEV
                     HQPLGPVDDHGHPLPLEYQGAPVPKKMNKLGSAGKPGTGSFLRADPWQESEQHFEIEHA
                     EEHRQLAVLQKRQELENGGKHSH"
     gene            complement(3700..4194)
                     /locus_tag="O3I_RS11690"
                     /old_locus_tag="O3I_011515"
     CDS             complement(3700..4194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350097.1"
                     /locus_tag="O3I_RS11690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011515"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_041563673.1"
                     /transl_table=11
                     /translation="MSLRYFYDCEFIEDGVVIDLVSIGVVCEDGREYYAVSTEFDPGRA
                     GPWVRRHVLPQLPSPSSPLYRSRTQIRDELYKFLVPRSSVVPELWAWVGAYDHVALCQL
                     WGSMVDLPSALPRYTNELRQHWDAHGRPELPPVPPDAHDALADARHNLAKFEAIEAARR
                     R"
     misc_feature    4154..4172
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.22"
                     /tool="antismash"
     gene            4352..5737
                     /locus_tag="O3I_RS11695"
                     /old_locus_tag="O3I_011520"
     CDS             4352..5737
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350098.1"
                     /locus_tag="O3I_RS11695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011520"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_014983120.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDRLPELPPLPTELRRRLDEALARPALQQPSWDPEQA
                     AVMRTVLESVPPICVPAEVEELREQLAEVARGEAFLMQGGDCAETFADNTEPHIRGNIR
                     TLLQMAVVLTYGASMPVVKVARIAGQYAKPRSSDTDSLGLKSYRGDMVNALVADAAMRE
                     HDPSRLVRAYANASAAMNLVRALTGAGMADLHKVHDWNRDFVAKSPAGARYEALAEEID
                     RGLAFMTACRVNDPSLKSARIYASHEALVLDYERAMLRLSENAAGEPVLYDLSAHFLWI
                     GERTRQLDGAHIALAELLANPIGLKIGPSTTPDQAVEYVERLDPNNEPGRLTIVSRMGN
                     SKVRDVLPPIIEKVQATGHQVIWQCDPMHGNTHEASTGFKTRHFDRIVDEVQGFFEVHH
                     ALGTHPGGLHIELTGEDVTECLGGAQDISDLDLSGRYETACDPRLNTQQSLELAFLVAE
                     MLR"
     gene            complement(5786..6253)
                     /locus_tag="O3I_RS11700"
                     /old_locus_tag="O3I_011525"
     CDS             complement(5786..6253)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS11700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_011525"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_014983121.1"
                     /transl_table=11
                     /translation="MTTQQISDAELAGQPAAYWTGLAYEALIAFTRIRLAELGMTQPQY
                     WILRNLSKADISPNGQGMTIPELRQAMSSYLRPEDDLDADSAVLLERGWLTRDEQQRWW
                     ITEAGDQARAAMGPGLPAIRAHIHRGIDDVDYVTTLKVLQQMIRNVGGTAQ"
     misc_feature    complement(6377..6392)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.8"
                     /tool="antismash"
     gene            6437..7369
                     /locus_tag="O3I_RS11705"
                     /old_locus_tag="O3I_011530"
     CDS             6437..7369
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016888478.1"
                     /locus_tag="O3I_RS11705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011530"
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="WP_014983122.1"
                     /transl_table=11
                     /translation="MLTYFEATVIGVVQGVTELFPISSLGHSVLLAAWLGGDWQRLVDQ
                     GETGTGTPYLAFVVALHVGTAVALLGYYWRDWRAIAVGFAGLLRTGRAETVAQRLALLI
                     VIATLPIAALGPFLQHPLHVLFAAPICAAIFLVLNGIVLIIGEGLRRRNEPTLAQYGRS
                     FALHGRAGVRTAEARKRRSDRRLAALEPEDALAIGFAQVGALLTGFSRAGLTMVGGLWR
                     GLQHEQAAKFAFLLATPAILGAGLMEIPELAGPDTAGIRGPVLVGAIVSGVSSWLAVRF
                     LERYFQTRTLLPFAVYCLIAGTVSIVRFL"
     gene            complement(7414..9354)
                     /gene="pknB"
                     /locus_tag="O3I_RS11710"
                     /old_locus_tag="O3I_011535"
     CDS             complement(7414..9354)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008715722.1"
                     /locus_tag="O3I_RS11710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011535"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_014983123.1"
                     /sec_met_domain="Pkinase (E-value: 2.6e-49, bitscore:
                     166.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEGRYRIDAPIARGGMSMVFRGVDTRLDRPVAIKVMDPKFAGDP
                     QFLTRFEFEARAVAKLKHPSLVAVYDQGVDGEYPFLIMELVEGGTLRELLRERGPMPPH
                     AVRAVAEPVLAAIGVAHSAGLVHRDVKPENVLISDAGEVKIADFGLVRAVAAANTTSAS
                     VILGTAAYLSPEQVTSGTADARSDVYSFGVLIFELLTGRVPFTGDTSISIAYQRIENDV
                     PSPSRFISGVPPEFDELVAKATAREPAHRFADANEMAAALRQIGAKLNLPPYRVPAPQE
                     SAEHLSASYKVATPAVQQPAATPAPPYTPPTVQHTRVVTAPRPRADYGPGDYDEQPVRQ
                     QHASTPYQSYAPDPNRSRRTAWIWIAVVAILTLVVGVGGWWLGFGRFSPVPAIAGLDTD
                     RAVATLRDAGFETELRQKASDTIPIGGVVGSDPSAGSRITKGSTVAVLVSSGKPKVPDL
                     NPGDDISKVNQLIRDAGLQPVDSGEEGNPAPKGTLARVEPGPGTVLPTGAQVKVYRSNG
                     AKPIKMPDVRGKTADEAVKLLTDAGIKVRDRQTKFDKSVEADKVIGTDPVAGTTVQSGS
                     GVTLFVSNALKMPNLIGSSVGNARSKLESLGLQVEVKQLTPTDGSVVIGQVPGISANVE
                     PGSTVQLTALP"
     misc_feature    9383..9398
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.82"
                     /tool="antismash"
     gene            9596..9964
                     /locus_tag="O3I_RS11715"
                     /old_locus_tag="O3I_011540"
     CDS             9596..9964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007297456.1"
                     /locus_tag="O3I_RS11715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011540"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_029893656.1"
                     /transl_table=11
                     /translation="MSAFPCSDDVLPESVALVPLPEVADRLGLVVTRVHQMLRDHQLLA
                     IRRDGVAGVPERFFDKEGAVVKPLPGLITVMKDAKYTDEEILQWIFTDDDSLPGKPIDA
                     LHGPLAREVVRRAAADPF"
     gene            complement(10001..11023)
                     /locus_tag="O3I_RS11720"
                     /old_locus_tag="O3I_011545"
     CDS             complement(10001..11023)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350102.1"
                     /locus_tag="O3I_RS11720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011545"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_014983125.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.3e-96, bitscore:
                     320.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.4e-56,
                     bitscore: 190.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGFAPPAVERARRGTAAELAVAYRACRQIAARYGRTYFLATRLL
                     SAERRPAIHALYAFARVVDDIVDHAETGAVQRFPDGTGGERSALAPAAQLDLIERRLRA
                     LLDGTVPAPDALSHKTFEAHRLALLALADTIERYDIAAAHFWTFLDAMRMDVPGTAQFR
                     DRYATMTELREYMRGSAAAIGLQVLPVLGTVVPRAEAEPAAAALGEAFQLTNFLRDVAE
                     DLDRGRMYLPADELAPFGVDHDLLTHCHRAGHTDARVRRGLAHLIAVNRDIYRHADAGI
                     DLLEPRVRPAIRTASLLYAGILDRIEDSGYAVFTQRAVVPRPRRLRVAATQFATALTGR
                     "
     gene            complement(11020..12603)
                     /locus_tag="O3I_RS11725"
                     /old_locus_tag="O3I_011550"
     CDS             complement(11020..12603)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046202.1"
                     /locus_tag="O3I_RS11725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011550"
                     /product="alpha-(1->6)-mannopyranosyltransferase A"
                     /protein_id="WP_237748365.1"
                     /transl_table=11
                     /translation="MRTSAVFLRTPEGHAALLGFYGAIMITLGGFGAGSTRKRDPLLEA
                     LHLSWLRYGHGYALCTIVIWIGVLLMITAWVRLGRATIGKGDRPDVPVTLNELRAIVGI
                     WITPLLFAVPMFSQDVYSYLAQGALLRDGFDPYVDGPVKNPGVLLDNVSPVWKNTTAPY
                     GPIFLLLGRGITSITGENVVAGTIAMRLVMLPGLALMMWAVPYLTKHLGGKPTVALWLA
                     VLNPLVLIHLFGGVHNEMLMVGLMCAAIALVLERHHVAGIVVLAIGVAIKATAGVALPF
                     LVWIWMLHERERRAAQRTRRAPDQLPESERPHDAAEPTEDMPHPALMFAKIAGLGLSVF
                     AAVFVAASAIAGVGIGWLTALSGSKKIINWLSLPTIMMHMVGWVTTLDGGKVLNVTRLL
                     CMLALVALLAWTWWRFRHSEREAVFGILIAFVAIVILSPAALPWYYSWPLALAAGFALS
                     TTTLMVLVGVCTWLMLVFQPDGSIGLYSFWHVAAATFAAVVAALSLRTVDPLRLRAATP
                     STEPATPART"
     misc_feature    complement(11686..11688)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12847..14379)
                     /gene="crtI"
                     /locus_tag="O3I_RS11730"
                     /old_locus_tag="O3I_011555"
     CDS             complement(12847..14379)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748886.1"
                     /locus_tag="O3I_RS11730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011555"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_014983127.1"
                     /sec_met_domain="DAO (E-value: 3.4e-14, bitscore: 52.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDVKTVAGPTDRVVVVGAGLSGLSAALYLTGAGRQVTLLERADH
                     PGGRVGRYQGADYEIDSGATILTLPELVADALAAVGRTPETCKPALRIHQLAPSYHARF
                     ADRTELRVFADADAMAAEVAAVCGPAEARRYRRLRDWLARIYAAEYAEFMDTNFDSPLD
                     LVRLPEKRRALATLVRLGGFGRLGPRVGRFLRDPRLARLFTFQALYAGLPPTAALSVYG
                     AIPHMDTSLGVYFPEGGMRAIASAMAEAFTAAGGTLELGTEVTGVDYTRRRATRVRTAD
                     GRGFDCDALVLTADLGAIDRFGVRRRRGLRAAPSAVVAHGTVPAALARTWPVQAHHIIE
                     FGQAWRQTFAEITGRRGRGRLMSDPSLLLTRPALTDPGLHITRADGAHEPLSVLAPCPN
                     LDSAALDWRRIGPAYLRELLGVLEARGYHGIAEHFTVDHLDTPRTWQEQGMLAGTPFSA
                     AHLFRQTGPFRPRNFPHASDNVVIAGCGTTPGVGVPTTLLSGKLAATRITGE"
     gene            complement(14453..15541)
                     /locus_tag="O3I_RS11735"
                     /old_locus_tag="O3I_011560"
     CDS             complement(14453..15541)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350105.1"
                     /locus_tag="O3I_RS11735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011560"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_237748366.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.5e-48, bitscore:
                     162.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAPIPGTPAFVAAVEGALTRFFADRRGTVEELGPVFVEAADALE
                     LFVLRGGKRTRPAFAWTGWLGAGGDAAGPDAAAVLTACAALELVQACALIHDDIIDSSR
                     TRRRFPTVHVDFETRHRDRGWAGDSAHFGASVAILVGDLALAWADDMVHASGLEPTAIA
                     RFAPVWAGMRTEVLGGQLLDINGEAGGDESVEAALRINRYKTAAYTVERPLHLGAAIAD
                     ADADLVAAYRTFGTDIGIAFQLRDDLLGVFGDPAITGKPSGDDLREGKHTVLLAEALRR
                     ADASDPAAAKLLRTSVGTDLDADEVAHLRTVLTDLGAADEVERRITELTDAGLAAIETS
                     TATPAAKQQLRAMALAATKRTA"
     misc_feature    15767..15782
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            15791..16711
                     /locus_tag="O3I_RS11740"
                     /old_locus_tag="O3I_011565"
     CDS             15791..16711
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0006555 - methionine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350106.1"
                     /locus_tag="O3I_RS11740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011565"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_051066572.1"
                     /transl_table=11
                     /translation="MVQSLRTHSGTSVPFSVEFNPPRDAPAEARLWRAVRQFERMHPAF
                     VSMTYGAGGSTRDRTVRVTGALAQETTLLPVAHLTAVEHSVAELRSLVGSYADSGIRNI
                     LVLRGDPPGDPLGAWQRHPEGVEYAEELVRIVRDLGDFHVGVASFPQGHHRSPDLDSDT
                     AFLTAKLRAGAEYSITQMFFDVEHYLRLRDRVLKFDPIEGAKPIIPELMPITSLRTVAR
                     AEELCGRTLPPAVLARLHHAAGDAPDGNPAAVREAGIEIATEMAQRLIDEGAPCLHFIT
                     LNFAKATTEVLTNLGYGVTAAPISA"
     gene            complement(16747..18774)
                     /locus_tag="O3I_RS11745"
                     /old_locus_tag="O3I_011570"
     CDS             complement(16747..18774)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014988582.1"
                     /locus_tag="O3I_RS11745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011570"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_041562567.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 8.2e-06, bitscore:
                     24.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIALGRRWARWFVGAVALLTVSQVVVAAPGAATPEGAAAWTALH
                     DGPQRFPSIHIDWDVPITMSDGTVLKANVYRPADAHGPIDTPFPTIVNMTPYTKLGSMV
                     LQTALSVPVLSDAVVGLLRDFELPGTPLEGLTDATRVAGGGFGRVFSVDPNLIRSGYTQ
                     IVVDVRGTGFSQGNWEPWGPKDQSDTPEVIAWAAAQPWSDGNIGMNGVSYSGINQVQAA
                     EKQPPALKAIVPVVPGNDLVRDMIAPGGAAIGILLPYLLVVNAAKLMPDLMSLLQGRFD
                     TQWLADRLADPLSFLDVGLQTLTADSFDTIPPQLSNVLDPDSPIRQAWLGHPERIQVPT
                     MVIGGWHDNFVNGEPRIYQDIPLPPGQKQLVMGNGYHVSTGFDMRGKPGEPPRIDVLQR
                     AWFDKWLKGIDNGIDQWGPVTMWQQGGGWTTAEQFPRPEAEHRRMYLSAAPSGTSALSA
                     HDGSLVTAATADNARLTVAPGLASLCSADGTQGTAGILVFTGCGKDARIQEVSGLTFTS
                     PPVTEPTTLSGPIAVHLNTVHDATDGYWTATLNDVAPDGRSVTLSTGQLMASMRAVDDG
                     RSRRSADGAYTDPFPVMSLAARQTVVPGQATQLDLGLAPTDAILQPGHRLRLDVFAGNY
                     PKGLPIRPMLDGTGLKPQHLQLDPAEPSYVNVPLSGTTGW"
     misc_feature    complement(18878..18894)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            complement(18964..20115)
                     /locus_tag="O3I_RS11750"
                     /old_locus_tag="O3I_011575"
     CDS             complement(18964..20115)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046208.1"
                     /locus_tag="O3I_RS11750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011575"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_014983131.1"
                     /transl_table=11
                     /translation="MTVPLSILDLAPISAGSTAQQALRNTVDLAQRAEQWGYHRYWLAE
                     HHFVSVASSASITLIGLVAAATSRIRVGSAAVQVGHHTSASIVEAFGTIDALYPGRLDL
                     GLGRSGHRRSQYGSEPAHPKGGHPRVDTATGRTEIRDGVVVPPPFDPGRITDRSKFLAS
                     ISALQQRGAQAPPFDEQVDEVRALLDGSFVSPEGVALHAVPGEGAQVQLWVFGSSAGES
                     AELAGRLGLPFAAAYHVAPGTALDAVAAYRDAFRPSAQLAEPYVVVSADVVVAADDATA
                     QQHAATYGHWVHSIRSGAGAADYLDPATTPPLTPEQHRLVDDRLATQFVGSPSTVTSRL
                     AALQQHTGADELLVTSVTHHHEDRLESHRLLADAWGLRTARAA"
     gene            complement(20112..20939)
                     /locus_tag="O3I_RS11755"
                     /old_locus_tag="O3I_011580"
     CDS             complement(20112..20939)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014350107.1"
                     /locus_tag="O3I_RS11755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011580"
                     /product="DUF1684 domain-containing protein"
                     /protein_id="WP_014983132.1"
                     /transl_table=11
                     /translation="MTTSISTVFETEWAQWQHAREDQLRDPLGFLSLTALHWLTDQPER
                     LPDVPGTWWVTDDKVFITAQPADRLDYDGERIAGVQIITPAEGAPGLTVRHEDRVLEVI
                     RRTGLYAVRVHDPAAPTLLSFTGIPSYAPDPRWVLSGKFTPLDEPQTVTTGAVVDGLEH
                     HHTASGTIEFTLGAVTERVLAFGDPTDLRLLFTDATSGVTTYPAARSLAVGAPEADGTV
                     RLDFNRAANLPCAFTDFATCPLAPEQNRLRVAIEAGEQHPGLPHGELSERRTA"
     gene            complement(20936..22306)
                     /locus_tag="O3I_RS11760"
                     /old_locus_tag="O3I_011585"
     CDS             complement(20936..22306)
                     /EC_number="1.14.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046210.1"
                     /locus_tag="O3I_RS11760"
                     /note="This protein belongs to a clade of FMN-dependent
                     monooxygenases, within a broader family of flavin-dependent
                     oxidoreductases, the luciferase-like monooxygenase (LMM)
                     family, some of whose members use coenzyme F420 rather than
                     FMN; Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="O3I_011585"
                     /product="NtaA/DmoA family FMN-dependent monooxygenase"
                     /protein_id="WP_014983133.1"
                     /transl_table=11
                     /translation="MTGKPRKPIHLAAHFPGVNNTTVWADPASKSQVDFASFVHLAQTA
                     ERGLFDFFFLAEGLRLREHLGRIHDLDVVGRPDTFTVLDALAGVTGKLGLAGTINSTYN
                     EPFELAKQFASLDHLSGGRAAWNVVTSSDAFTGENFRRGGYLEHSRRYQRAAEVVEVTR
                     KLWDSWAADTLVVDRAAGVFAREVPETRHRGSQFDIAGRFVLPPSPQGHPVLLQAGDSD
                     DGREFGAAAADAIFTVHGTLEAGQRFYTDVKNRLAKYGRTPDELKILPAATFVLGDSAQ
                     DAEERARHIRQQQVGPQTALAFLEQVWGRDLSGYDPDGPLPDVDPADNADITRGRVRHA
                     KDPRAVAEAWRARATAENLSIRELIIEVTARQQFVGTPAAVAEQIDTYVQADASDGFIL
                     VPHLTPGGLDEFVDKVVPELQERGSFRTEYTGTTLRDHLGLRHPHHRTTAHEGARAS"
     misc_feature    22278..22291
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     gene            complement(22401..23522)
                     /locus_tag="O3I_RS11765"
                     /old_locus_tag="O3I_011590"
     CDS             complement(22401..23522)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046211.1"
                     /locus_tag="O3I_RS11765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011590"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_014983134.1"
                     /transl_table=11
                     /translation="MTESDFFLAVELAGTGAHPASWRRPDSRAEELFTGGYWVDAVTAI
                     EKAGADAVFLPDSFGLQPGGPGVTRGRLDAVAIAARVAARTRRLGLLPQAPVTHTEPFH
                     LAKAIQSLDFATLGRAGWEVTVSEGEEQARAFGRKQAQDAASLWHEADEAIEVVTRLWD
                     SWEDDAEIRDVPTGRFIDRNKLHYIDFTGDHFAVKGPSITPRSPQGQSIVAVRAHDDPS
                     TGVAVRRADLIRITAAGLDAARSHRTALRTALRAAGRDPDAVRVLLDLDVHLAESADAA
                     SAEVAELDGWAAPPAETGVRHLGTAAALRDLLATVHRSAAADGVVLRPLAVPATLRHLP
                     ALGRTAVSSTTLRARLGLSRPVSRYTEKEGASA"
     misc_feature    complement(22467..22469)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(23522..23776)
                     /locus_tag="O3I_RS11770"
                     /old_locus_tag="O3I_011595"
     CDS             complement(23522..23776)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS11770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_011595"
                     /product="hypothetical protein"
                     /protein_id="WP_014983135.1"
                     /transl_table=11
                     /translation="MPDPTYRHSRVLVRTGHRPHCRSRPEPAQPPPGPVKRWWHTRLRP
                     PQRAAATALWQHAYFFAPDIGCAGTHPAARQCIDWKAPC"
     gene            complement(23776..25470)
                     /locus_tag="O3I_RS11775"
                     /old_locus_tag="O3I_011600"
     CDS             complement(23776..25470)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011595015.1"
                     /locus_tag="O3I_RS11775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_011600"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014983136.1"
                     /transl_table=11
                     /translation="MTTASSPRTATVEDRPGAVSCAEPAGREADPLLQVRNLRVRYRTD
                     TGPVTALAGVSLSVARGEVVALVGESGSGKSTLAQAVIGLLGSNAEISGGTVTFGGRLV
                     DLGSEQALRRLRGARIGFVPQDPGLSLNPVRRVGDQVAEALVVHRLADRRSARVRAVEL
                     LADAGLDRPELREVQYPHELSGGQRQRVLIASALACEPELVIADEPTSALDATVARRVL
                     DQLAAQISARGTAVLLITHDLAVAAERADRLVVLSGGEIVESGPTATVLAAPRHPYTKR
                     LLAAAPSLAPPRAYRPPKPREGAPLLALREVHKRFRAQAGGSVTAVAGVGFELGRGETL
                     ALVGESGSGKSTTARIALRLTDPDSGRVTFDGHELTRLRGTRLRTLRQRFQVVYQNPYA
                     SLDPRWRVGTIIEEPLRAYGVGDRAARQARVTELLGQVALPESFARRRPAELSGGQRQR
                     VAIARALALHPDLLVLDEPVSALDASVQAQILELLDRLQAELALSYLFISHDLAVVRRI
                     SDHVAVMRHGRIVESGPTAAIFDDPQHEYTRELLSAIPTPALAKGQA"
ORIGIN
        1 cgcggcggcc ctgacgccga acccgcagct cgcgaccgcg aacgacgaca agtccgcgct
       61 gatccgtgag ggcaaccagc tgtacgacac gtcctgcatc acctgccacg gtgcgaacct
      121 gcagggtgtc caggaccgcg gcccgagcct gatcggcgtc ggtgaagccg ccgtctactt
      181 ccaggtctcc tccggccgga tgccgatggc ccgcaacgag gcccaggcgc agcgcaagcc
      241 cgccaagttc gacgagcacc agaccgacgc gctgatggcg tacgtcgcgg ccaacggcgg
      301 cggccccagc gtggtccgtg acccgaacgg cgagatcgcc caggagtccc tgcgtggcga
      361 cgacatcgct cgcggctccg agctgttccg catgaactgc gcgtcctgcc acaacttcac
      421 cggccgcggc ggtgcgctgt cctccggtaa gttcgcgccg ccgctggagc ccgccagcga
      481 gcagcagatc tacgacgcga tgatctccgg cccgcagaac atgccgaagt tctccgatcg
      541 gcagctgacc ccggaagaga agcgcgacat catcgcctac gtgatgaacg cgaaggaaga
      601 gcgcgccccc ggcggctggg acctcggtgg gttcggtccc gcgaccgagg gtctggtcat
      661 ctgggtggtc ggcatcacgc tggtcgtggg tgccgcgatt tggatcgggt cccggtcatg
      721 agcacgtcag ccccggaggc ggtagctccg cgtgaccacg caggggccgg gcgcatgacc
      781 cgaaggatgc agtcatgact gagaaggagc ctaacgtggg tcggccggat gagggccacg
      841 acggcgtcga gccgtcgaac gagcaggtca caggggccgg cgcccatgtg gccaagactg
      901 acggccatgc gctgacggag ccgaccgagg ccgaactcga cgcgatgagc cgcgacgagc
      961 tggtcaagct cggcaccgag cgcgacggcg tcgatgtcgc ctaccggcgc gagcggttcc
     1021 cggtgccggg tacccgcgcc gagaagcggg ccgagcgcgc ggtcgcgttc tggtttgccg
     1081 tgtccggcat cgccgcggcc gccctggtcg gtgtgttcct gttctggccg tgggagttca
     1141 aggccaacaa ggaggacggc cacgccgcct actcgctgtt cacgccgctg gtcggtatca
     1201 ccttcggtgt ctcggtgctg gtcatcggca tcgcggtggt gttgatccgc aagctgttca
     1261 tcccggccga actgtccatc caggaccggc acgacggtcc gtcgcccgag gtcgagcgcc
     1321 gcacgctggt cgccgaactg agcgacgcgc tggagacctc cacgctcgcc cgccgcaagc
     1381 tgatcacccg caccgccggc gccggtgtcg gtgtgctcgg catcggcgcg ctgctggtgt
     1441 tcgtcggcgg catggtgaag aacccgtggg ccaagggcga caagtcgccg ctgtgggtgt
     1501 ccggctggac ccccgactac gagggcgaga ccatctacat ccggcgcgac accggtcgcc
     1561 cggaggacat cgtgctggtg cgtccggagg atctggacgc gggcgccatg gagacggtgt
     1621 tcccctggaa agagaagtgg cgcggcgacg agcacgccac cctgcagtcg ctgcgcggta
     1681 tccgcaaccc ggtcatgctg attcgcctgc gcaccgaaga cgcgcagaag gcgatcaagc
     1741 gcaagggtca ggagagcttc aactacggcg actacttcgc ctactcgaag atctgcaccc
     1801 acctcggttg cccgacatcg ctgttcgagc agcagaccaa caagatcctg tgcccctgcc
     1861 accagtcgca gttcctggcg accgagtggg gtaagccggt cttcggtccc gccgcccgcg
     1921 cgctgccgca gctgccgatc accgtcaact ccgagggctt cctggtcgcc aacggcgact
     1981 acatcgagcc gctcggaccg gccttctggg agcgtcgttc atgagccctt ccgttgcagc
     2041 tcaggcgaac gaggcggacg agcgctatcg cgccgccgcg ttcatgaagc ggtcgatcaa
     2101 caaggtcttc ccgacccact ggtcgttcct gctcggtgag atcgcgctgt acagcttcat
     2161 cattctgctg ctgtcgggcg tctacctgac cctgttcttc gatccgtcga tgaccgaggt
     2221 cgtctacaac ggcgcgtacc agccgctgcg tggtgtcacc atgtcgcggg cctacgagtc
     2281 gtcgctgaac atcaccttcg aggtgcgcgg cggtctgttc gtgcgccagg tgcatcactg
     2341 ggcggcgctg ctgttcgcgg cgtcgatcat catccacctg ttccgcatct tcttcaccgg
     2401 cgcgttccgc aagccgcgtg aggcgaactg ggtgatcggc tgcctgctgc tgatcctggc
     2461 gatgttcgag ggcttcttcg gttactcgct gcccgacgat ctgctgtccg gcaccggcct
     2521 gcgcgccgcg ttcggcggta tcacgatgag cgtgccgatc gcgggcacct ggttgcactg
     2581 gctgatcttc ggcggtgatt tccccggcga catcatcatc ccgcgcctct acatcgcgca
     2641 cgtgctgctg ttccccggca tcatcctggc cctgatcgcc gcgcacgtcg cgctggtctg
     2701 gtaccagaag cacacccagt tccccggccc gggccggacc gagaacaacg tggtcggcgc
     2761 gcgcatcgtg ccggtgttcg ccgcggacca gggcgcgttc ttcgcgttca ccctcggcat
     2821 cgtcggcatc atgggtggcg tcttccagat caacccgatc tggaacctgg gcccgtacaa
     2881 cccgtctcag gtgtcggcgg gttcgcagcc ggacttctac atgatgtgga ccgacggcct
     2941 ggcccggctc atgccgccgt gggagctgta cctgggtcgc tacaccgtgc ccgcggtgtt
     3001 ctgggtcgcg ttgatcatgg gcttggtgtt caccgtcctg atcgcctacc cgtggatcga
     3061 gaagcggctc accggcgatg tgggttcgca tcacaacctg ctgcagcgtc cgcgcgatgt
     3121 gccggtccgt accgcgatcg gcgccatggc gatcggtttc tacgtggtcc tgacgctgtc
     3181 ctgcgtcaac gacatcctgg cgctcaagtt cgacatctcg ttgaacgcga ccacctggat
     3241 gggccgcatc ggcctgctcg tggtgccgcc ggtggcgtac ttcgtcgcct accggttctg
     3301 catcggcctg cagcgcagcg accgggcggt gctcgagcac ggcatcgaga ccggtgtgat
     3361 caagcgcctg ccgcacggtg agtacatcga ggtgcaccag ccgctcggcc cggtcgacga
     3421 tcacggtcac ccgctgccgc tggagtacca gggcgccccg gtcccgaaga agatgaacaa
     3481 gctgggttcg gcgggtaagc cgggcaccgg tagcttcctg cgggccgacc cgtggcagga
     3541 gagcgagcag cacttcgaga tcgagcacgc cgaggagcac cgtcagctcg cggtgttgca
     3601 gaagcgccag gagctcgaaa acggtggcaa gcacagccac tgacagctga caacgaaggc
     3661 cccgagtcgg attcgactcg gggccttcgt cgttcgtggt cagcgccggc gggccgcttc
     3721 gatggcttcg aatttggcca ggttgtgccg ggcgtcggcc agggcgtcgt gcgcgtccgg
     3781 cgggaccggg ggcagttcgg ggcggccgtg cgcgtcccag tgctggcgta gttcgttggt
     3841 gtagcggggg agtgcgctgg gcaggtcgac catcgagccc cacagctggc agagcgccac
     3901 gtggtcgtag gcgccgaccc aggcccacag ttcgggcacc accgacgagc gcggcaccag
     3961 gaacttgtac agctcgtcgc ggatctgggt gcgactgcgg tacagcggcg aggacggcga
     4021 gggcagttgc ggcagcacat gcctgcgcac ccacggcccg gcccggcccg ggtcgaattc
     4081 ggtggatacc gcgtaatatt cgcggccgtc ctcgcagacc acaccgatgg agaccaggtc
     4141 gatgaccacc ccgtcctcga tgaattcgca gtcgtaaaaa tatcgaagcg agatcgctct
     4201 actcctccgc agttcggtgt tgcccccgga tatgtctcgg tcaatcaccc taagcggggt
     4261 gggggcgcga ttcgcatcgg ggcagggtgg tggttgtcac cacccctacg gtgggtacca
     4321 cggccgtccg aagggtccgt attctgaacg agtgaactgg accgtcgacg tacccatcga
     4381 tcgcctgccg gaactgccgc cgctgcccac ggagctgcgc aggcggttgg acgaagcgct
     4441 ggcccgccct gcgctacagc agccgtcgtg ggatccggaa caggcggcgg tgatgcgcac
     4501 cgtgctggag agcgtgccgc cgatctgtgt gcccgccgag gtggaggagc tgcgcgaaca
     4561 gctcgccgag gtggcccgcg gcgaggcgtt cctcatgcag ggcggtgact gcgcggagac
     4621 gttcgccgac aacaccgagc cgcatatccg cggcaacatc cgcaccctgc tgcagatggc
     4681 ggtcgtgctc acctacggcg cgagcatgcc ggtggtcaag gtggcccgga tcgcggggca
     4741 gtacgccaag ccgcgctcct ccgacaccga ttcgctcggc ctcaagtcct accgcggcga
     4801 tatggtcaac gcgctcgtcg ccgatgccgc gatgcgcgaa cacgatccgt cgcggctggt
     4861 gcgcgcgtac gccaacgcga gcgccgcgat gaacctggtg cgcgcgctga ccggcgcggg
     4921 catggccgac ctgcacaagg tgcacgactg gaaccgcgac ttcgtcgcga agtcgcccgc
     4981 cggtgcgcgc tacgaggcgc tggccgagga gatcgaccgc ggtctcgcgt tcatgaccgc
     5041 ctgccgggtg aacgatccga gcctgaagtc ggcgcgtatc tacgccagcc acgaggcgct
     5101 cgtcctcgac tacgagcggg cgatgttgcg gctgagcgag aacgcggcgg gcgagccggt
     5161 gctctacgac ctgtccgcgc acttcctctg gatcggcgag cggaccaggc agctcgacgg
     5221 cgcgcatatc gcgctcgccg aactgctcgc gaacccgatc ggcctgaaga tcggcccgtc
     5281 caccacgccc gatcaggccg tggagtacgt cgagcggctc gatccgaaca acgagcccgg
     5341 ccggctgacc atcgtgtccc ggatgggcaa cagcaaggtc cgcgacgtgc tgccgcccat
     5401 catcgagaag gtgcaggcca ccggtcacca ggtgatctgg cagtgcgacc cgatgcacgg
     5461 caacacgcat gaggcgtcca ccggtttcaa gacccggcat ttcgaccgca tcgtcgacga
     5521 ggtgcagggc ttcttcgagg tgcatcacgc gctcggcacc catccgggcg gcctgcacat
     5581 cgagctcacc ggcgaggacg tcaccgaatg cctcggcggc gcccaggaca tctccgatct
     5641 ggacctgtcc ggtcgctacg aaacggcctg cgacccgcgc ctgaacaccc agcagtcgct
     5701 ggagctggcg ttcctggtcg ccgaaatgct gcgctgagca aggctttccg gagggtgcgt
     5761 actcggccga gtatgcaccc tccggctatt gtgcggtgcc gccgacgttg cgaatcatct
     5821 gctgcagcac cttcagcgtc gtgacgtagt cgacgtcgtc gatgccccgg tggatatgcg
     5881 cgcggatcgc gggcaggccc ggccccatcg cggcgcgcgc ctggtcgccc gcctcggtga
     5941 tccaccagcg ctgctgctcg tcgcgggtga gccagccgcg ttcgagcagc accgccgagt
     6001 cggcgtcgag gtcgtcctcg gggcgcaggt acgagctcat cgcttggcgc agttcgggaa
     6061 tcgtcatgcc ctgtccgttg ggtgagatgt cggccttgga caggttccgc agaatccagt
     6121 actgcggctg cgtcatcccg agttcggcca gccggatgcg ggtgaacgcg atcagcgcct
     6181 cgtaggcgag tccggtccag taggcggcgg gctgtccggc cagctccgca tccgagatct
     6241 gctgtgtcgt catgattgtt cctctgttcg ttcgtcctgg ccaccataaa agctcaagtt
     6301 tggttgaggt caaatcggcg atcgcggcgc tgcggtcgat atccgaaagt cactggggga
     6361 taggtgattc gggcatatcg gtctagagct gtggtgggtg cgggtaggcc actgtggccg
     6421 tgcgaaactc ttcgcgatgc tcacttactt cgaagcgacg gtcatcggtg tggtgcaggg
     6481 cgtcaccgag ctgttcccga tctccagcct ggggcattcg gtgttgctcg cggcgtggct
     6541 cggcggggac tggcagcggc tggtcgatca gggtgagacc ggcacgggca caccgtattt
     6601 ggccttcgtg gtggccttgc acgtggggac cgcggtggcg ctgctcggct actactggcg
     6661 ggactggcgg gccatcgccg tcggattcgc gggcctgctg cgcaccggcc gggccgagac
     6721 ggtcgcccag cggttggcct tgttgatcgt gatcgccact ctcccgatcg cggccctggg
     6781 gccgtttctg caacatccgc tgcacgtgct gttcgcggcg ccgatctgtg ccgcgatctt
     6841 cttggtgctc aacggcatcg tgttgatcat cggcgagggc ctgcgccgcc gcaacgagcc
     6901 gacgctcgca cagtacgggc gaagtttcgc gctgcacggc cgggccggcg tgcgcaccgc
     6961 ggaagctcgt aagcgccgat cggatcgacg cctggccgcg ctcgagccgg aagacgccct
     7021 tgccatcgga ttcgctcagg tcggcgcctt gctgaccgga ttcagccgcg cgggactgac
     7081 catggtcggc ggactgtggc gtggcctgca gcacgagcag gcggcgaaat tcgcgttcct
     7141 gctggccact ccggcgatcc tgggtgcggg cctgatggag atcccggagc tggccgggcc
     7201 ggacaccgcc ggaatccgcg gaccggtgct ggtcggcgcg atcgtctccg gagtgtcgtc
     7261 gtggttggcg gtgcgcttcc tggagcgtta cttccagacg cgcaccctgc tcccgttcgc
     7321 ggtctactgc ttgatcgcgg gaacggtatc gatcgtccga ttcctctgat tccgtgtgtc
     7381 gttcgagcgc gacggccgaa acctgttgtc gcgctagggc agtgccgtca gctggacagt
     7441 ggatcccggc tcgacgttcg cgctgatccc cggcacctgg ccgatcacca ccgagccgtc
     7501 ggtgggcgtg agctgtttga cctcgacctg caggcccagg ctttccagct tggatctggc
     7561 gttgccgacg ctcgacccga tcagattggg catcttgagc gcgttggaga cgaaaagcgt
     7621 tacgccgcta ccggattgga cggtggtccc ggcgaccgga tcggtgccga tcaccttgtc
     7681 cgcctcgacg gacttgtcga atttggtctg ccggtcgcgc accttgatgc ccgcgtcggt
     7741 gagcagcttc actgcttcgt ctgccgtctt gccgcgcacg tcgggcatct tgatcggctt
     7801 cgcaccgttg ctccggtaca ccttcacctg cgcgccggtc ggcagcacgg tgccgggacc
     7861 gggctctacc cgcgcgaggg tgcccttcgg tgcgggattg ccttcttcgc cggagtccac
     7921 cggttgcagc cccgcgtcgc ggatcagctg attgaccttc gagatgtcgt caccgggatt
     7981 gaggtccggc accttcggtt tgccgctgga gaccagcacc gcgaccgtcg accccttggt
     8041 gatccgcgat ccggcggacg ggtcgctgcc gaccacgccg cctatcggga tggtgtcgga
     8101 ggccttctgc cgcaactcgg tctcgaatcc ggcgtcgcgc aaggtcgcga ccgctcggtc
     8161 ggtgtcgagg ccggcgatcg cgggcaccgg cgagaatcgc ccgaacccga gccaccagcc
     8221 gccgacgccg accaccagcg tgagaatcgc cacgacggcg atccagatcc acgccgtgcg
     8281 ccgcgaccgg ttcggatccg gtgcgtagga ctggtacggg gtcgacgcgt gttgctggcg
     8341 taccggctgc tcgtcgtagt cgccggggcc gtagtccgcg cgcgggcgcg gcgcggtgac
     8401 cactcgcgtg tgctgcaccg tcggcggcgt gtacggcggc gcgggggtcg ccgcgggctg
     8461 ctggacggcc ggggtggcca ctttgtaact ggcactcagg tgttcggccg actcctgcgg
     8521 cgcggggacc cggtagggcg gcaggttcag cttcgcgccg atctgccgca gcgccgccgc
     8581 catctcgttc gcgtcggcga accggtgcgc cggctcgcgc gcggtggcct tcgcgaccag
     8641 ctcgtcgaac tccggcggca caccggagat gaaccggctc gggctcggca cgtcgttctc
     8701 gatccgctga taggcgatcg agatcgaggt gtcgccggtg aacgggacgc gcccggtcag
     8761 cagctcgaag atcagcacgc cgaacgagta gacgtcgctg cgcgcgtcgg ccgtgccgct
     8821 ggtcacctgt tctggggaga ggtacgcggc cgtgccgaga atcacgctgg ccgaggtggt
     8881 gttggccgcc gccaccgcgc ggaccaggcc gaaatcggcg atcttgacct cgccggcgtc
     8941 ggagatcagc acgttctccg gtttcacgtc gcggtgcacc agccccgcgc tgtgcgccac
     9001 gccgatcgcc gcgagcaccg gctcggccac cgcgcgcacc gcgtgcggcg gcatcgggcc
     9061 gcgctcgcgc aacagctcgc gcagcgtgcc gccctccacc agctccatga tcaggaacgg
     9121 atactcgccg tccacgccct ggtcgtagac cgcgaccagg gaggggtgct tgagtttggc
     9181 gaccgcgcgg gcctcgaact cgaatcgggt gaggaactgc gggtcaccgg cgaacttcgg
     9241 gtccatcacc ttgatggcga cggggcgatc cagccgggta tcgacccccc ggaagaccat
     9301 cgacatgcca ccgcgggcga tcggcgcatc gatgcgatag cgcccttcca gcatttggcc
     9361 gatcaattga tgtcctccgg ctttcacaaa gttctcaccc ctcgcggttg cgcccacaag
     9421 cgatcgaccg ccccgtgcgg ccctcacgat ggtatcggcg aaacgcgccc gggtgtctca
     9481 cgacgtgcgg tgggggacgg tctaccgtta tcggcgtgag agagcgcagt gaacgaacca
     9541 acagcgcagc cgcagatgcg ctcatgacgg agccgagcgc cagcgaggcg cagtcatgag
     9601 cgcatttccc tgcagtgatg atgttcttcc ggagtccgtg gcgctggtgc cgctgcccga
     9661 ggtggccgac cggctcgggc tcgtggtgac ccgcgttcat cagatgctgc gcgaccacca
     9721 actgctcgcc atccgccgcg acggcgtggc aggtgttccc gagcggttct tcgacaagga
     9781 gggcgcggtg gtcaagcccc tgccgggcct gatcaccgtg atgaaggacg ccaaatacac
     9841 cgacgaggag atcctgcagt ggatcttcac cgacgacgac agtctgcccg gtaagccgat
     9901 cgacgctctg cacggcccgc tcgcccgcga ggtggtccgc agggcggcgg ccgatccgtt
     9961 ctgaccggcc gcacaggcgt gcgcacggcc cggccgggcg tcagcgtccg gtcagggcgg
    10021 tggcgaactg tgtcgcggcg acgcgcaggc ggcgcggccg tgggacgacc gcgcgctggg
    10081 tgaacacggc gtagcccgag tcctcgatgc ggtcgaggat gccggcgtac agcagcgagg
    10141 cggtgcggat cgcgggccgc acgcgcggtt ccagcaggtc gatgcccgcg tccgcgtgcc
    10201 ggtagatgtc ccggttgacc gcgatcagat gggcgagccc gcggcgcacc ctggcgtcgg
    10261 tgtgaccggc gcggtggcag tgcgtgagca gatcgtggtc cacgccgaag ggggcgagtt
    10321 cgtcggcggg cagatacatc cggccgcggt cgagatcctc ggcgacatcg cgcaggaagt
    10381 tggtgagctg gaacgcctcg ccgagggccg cggccgccgg ttcggcctcg gcgcgcggca
    10441 cgacggtgcc gagcaccggc agcacctgca gtccgatggc ggccgccgag ccgcgcatgt
    10501 attcgcggag ttcggtcatc gtggcgtagc ggtcgcggaa ctgcgcggtg ccgggcacgt
    10561 ccatccgcat ggcgtcgagg aacgtccaga agtgcgctgc cgcaatgtca tagcgctcga
    10621 tggtgtcggc cagcgcgagc agcgccaggc ggtgcgcttc gaacgtcttg tgcgacaggg
    10681 cgtccggtgc ggggacggtg ccgtccagca gcgcgcgcag ccgacgttcg atcaggtcga
    10741 gttgcgcggc cggtgcgagc gcgctccgct cacctccggt gccgtccgga aaccgctgca
    10801 ccgcaccggt ttccgcgtgg tcgacgatat cgtccaccac tctggcgaac gcgtagagcg
    10861 cgtggatcgc cggtcgccgt tcggccgaga gcagccgggt cgccaggaaa taggtgcgcc
    10921 cgtaccgcgc cgcgatctgc cgacaggcgc gatacgccac ggcgagttcg gcggccgtgc
    10981 cgcgccgggc gcgttcgacc gcgggcggcg cgaaaccggt catgtccggg cgggcgtggc
    11041 cggttcggtg ctcggcgtcg cggcccgcag ccgcagcgga tcgaccgtgc gcagcgacag
    11101 ggccgccacc accgcggcga acgtcgcggc cgcgacgtgc cagaaggagt agagcccgat
    11161 cgagccgtcg ggttggaaca ccagcatcag ccaggtgcac actccgacga gcaccatcaa
    11221 tgtcgtggtg gacagcgcga atccggcggc cagcgcgagc ggccacgagt agtaccaggg
    11281 cagcgcggcg ggggagagga tgacgatcgc gacgaaggcg atcaggatgc cgaacaccgc
    11341 ctcgcgctcg ctgtgccgga accgccacca ggtccaggcg agcagcgcga cgagcgcgag
    11401 catgcacagc agccgggtca cgttgagcac cttgccgccg tccagcgtcg tcacccagcc
    11461 gaccatgtgc atcatgatgg tcggcagcga gagccagttg atgatcttct tcgagccgga
    11521 cagtgcggtc agccagccga tgccgacgcc cgcgatggcg gaggccgcga cgaagaccgc
    11581 cgcgaacacg ctcaggccga gtccggcgat cttggcgaac atcagcgccg ggtgcggcat
    11641 gtcctcggtc ggttccgcgg catcgtgcgg gcgttcgctc tccggtaact ggtccggcgc
    11701 gcgacgcgtg cgctgggccg cgcgccgctc gcgctcgtgc agcatccaga tccacaccag
    11761 gaacggcagc gcgacaccgg cggtcgcctt gatcgccacg ccgatcgcca gcaccacgat
    11821 gcccgcgacg tggtggcgct ccagcaccag cgcgatggcc gcgcacatca ggccgaccat
    11881 cagcatctcg ttgtgcacgc cgccgaagag gtggatcagc accagcgggt tgagcaccgc
    11941 gagccacagc gcgaccgtcg gcttgccgcc gaggtgcttg gtcagatacg gcacggccca
    12001 catcatcagc gcgaggccgg gcagcatcac cagccgcatc gcgatggtgc ccgcgacgac
    12061 gttctcgccg gtgatgctgg tgataccgcg accgagcagc aggaatatcg gcccgtaggg
    12121 cgcggtggtg ttcttccaga cgggactcac gttgtcgagc agcacgccgg ggttcttcac
    12181 cgggccgtcg acatacgggt cgaaaccgtc acgcagcagt gcgccctgcg ccaggtagga
    12241 gtagacgtcc tggctgaaca tcggcaccgc gaaaagcagc ggggtgatcc agattccgac
    12301 gatggcccgc aattcgttca acgttacggg cacgtcgggt ctgtcgccct tgccgatcgt
    12361 ggcgcggccc agccggaccc acgcggtgat catcagcagc acgccgatcc agatcacgat
    12421 cgtgcagagc gcgtagccgt ggccgtaacg tagccaggac aggtgtagcg cctcgagcag
    12481 cgggtcgcgc ttgcgggtgc tgcccgcgcc gaacccgccg agggtgatca tgatcgcgcc
    12541 gtagaacccg agcagcgccg cgtgtccctc gggggtgcgc aggaagacgg cactggtacg
    12601 catccaggac cgcacactcg acgtgtcggt ggcggccgat tcgcgctgcg ctgtggtttt
    12661 cggtgcgtgg ccgtcgatat ctgtcactgt ggcctttgcg gcgcgcgttt cgggggatgc
    12721 catctggtgt cggtcccccc gaatggtcag cggtcgcaac cgcgagtgaa taggtcggcg
    12781 cctagtttac ggcgtcgcac cgaaccctat cccgctggtc ctcggggttt catctcgagc
    12841 tggggcttat tcaccggtta tccgggttgc cgccagtttt ccggacagca gagtcgtcgg
    12901 cacgccgacc cccggtgtgg tgccgcaacc tgcgataacc acattgtcgc tggcatgcgg
    12961 aaaattgcgc gggcgaaatg gtccggtctg ccggaacagg tgagctgcgg agaagggagt
    13021 tccggcgagc atcccttgtt cctgccaggt gcgcggggtg tccagatggt cgacggtgaa
    13081 gtgctcggcg atgccgtggt aaccgcgcgc ttccaatacc ccgagcaact cgcgcagata
    13141 cgcgggcccg atgcggcgcc aatccagtgc ggccgagtcc agattcgggc acggagcgag
    13201 cacggacagc ggttcgtgcg caccgtctgc gcgggtgatg tgcagcccgg ggtcggtgag
    13261 cgctggacgg gtcagcagca gcgacgggtc gctcatcagc cggccgcggc cgcgtcgtcc
    13321 ggtgatctcg gcgaaggtct gccgccacgc ctgcccgaac tcgatgatgt gatgggcctg
    13381 caccggccag gtccgcgcga gcgccgcggg caccgtcccg tgcgcgacca cggccgacgg
    13441 cgcggcgcgc aggccgcggc ggcggcgcac gccgaaccgg tcgatggcgc cgagatcggc
    13501 ggtgagcacg agggcgtcgc agtcgaagcc acggccgtcc gcggtgcgga cccgggtggc
    13561 gcgccgccgc gtgtagtcca cgccggtgac ctcggtgccg agttcgagcg tgccgcccgc
    13621 cgcggtgaac gcctcggcca tggccgaggc gatggcccgc atgccgcctt ccgggaagta
    13681 gacgcccagc gaggtgtcca tgtgcgggat cgcgccgtac accgagagcg ccgcggtggg
    13741 cggcaggccc gcgtacagcg cctggaaggt gaacagccgg gccagtcgcg ggtcgcgcag
    13801 gaagcgcccg acccgcggcc cgagcctgcc gaacccgccg agacgcacca aagtcgccag
    13861 ggcgcgccgc ttttcgggca gccgcaccag gtccagcggc gaatcgaaat tggtgtccat
    13921 gaattcggcg tactcggcgg cgtagatccg ggccagccag tcccgtagtc gccgatagcg
    13981 gcgggcctcg gcggggccgc agaccgccgc gacttccgcc gccatcgcgt cggcgtcggc
    14041 gaacacccgc agttcggtgc ggtcggcgaa gcgggcgtgg tagctcggcg cgagctgatg
    14101 gatgcgcagc gcgggcttgc aggtctcggg tgtgcggccg accgcggcga gcgcgtcggc
    14161 gaccagctcg ggcagcgtca aaatggtggc gccggagtcg atctcgtaat ccgccccctg
    14221 atagcgcccg acccggccgc ccgggtgatc ggctcgttcg agcagggtga cctggcgtcc
    14281 ggcgccggtc agatacagag ccgcggacaa gccggatagt cccgccccga cgacgaccac
    14341 gcgatccgtc ggtccggcaa cggttttcac gtcaggcatg cggttctcct cggtgccggg
    14401 cagcgatcgg tgccgctcag gtgtacccga tcggccggtg ccgcagctac tttcacgcgg
    14461 tgcgtttggt cgcggccaag gccatggcgc gcaattgctg cttcgcggcg ggtgtcgcgg
    14521 tgctcgtctc gatggcggcc aagcccgcgt cggtcagctc ggtgatccgg cgctccacct
    14581 cgtcggcggc gccgagatcg gtgagcaccg tgcgcaggtg ggccacctcg tccgcgtcga
    14641 gatcggtgcc gacgctggtg cgcagcagtt tcgcggccgc cgggtcggac gcgtcggcgc
    14701 ggcgcagggc ttcggccagc agcaccgtgt gtttgccttc gcgcagatcg tcgccggagg
    14761 gtttgccggt gatcgcgggg tcgccgaaga cgccgagcag gtcgtcgcgc agctggaacg
    14821 cgatgccgat atcggtgccg aaggtgcggt aggccgcgac cagatcggcg tcggcgtcgg
    14881 cgatggccgc gccgaggtgc agcgggcgct cgacggtgta ggcggcggtc ttgtaccggt
    14941 tgatgcgcag cgccgcctcg accgactcgt cgccgcccgc ctcgccgttg atgtcgagca
    15001 gctgaccgcc gagcacctcg gtgcgcatgc cggcccacac cggggcgaac cgggcgatgg
    15061 ccgtcggttc gagaccggag gcgtgcacca tgtcgtcggc ccaggccagg gccaggtcgc
    15121 cgaccaggat ggccacgctg gcgccgaagt gcgcggaatc acccgcccag ccgcggtcgc
    15181 ggtgccgggt ttcgaagtcg acgtgcaccg tcgggaagcg gcggcgggtg cgcgaggaat
    15241 cgatgatgtc gtcgtggatc agcgcgcacg cctggaccag ttccagggcc gcgcacgcgg
    15301 tcaaaacggc ggcggcgtcc gggcccgcgg cgtcgccgcc cgcgccgagc cagccggtcc
    15361 acgcgaacgc gggcctggtg cgtttgccgc cgcgcagcac gaacagttcc agcgcgtccg
    15421 cggcctcgac gaagaccggg ccgagctcct cgaccgtccc gcggcggtca gcgaagaacc
    15481 tggtcagcgc gccttccacg gccgcgacga aggcgggcgt ccccgggatc ggcgcgatca
    15541 gctcggccgc cgaggtgcgg tgcggcgtct gggtaccggt tccggcggac agcgtggcct
    15601 ccaaggtcgg gttgccgggc gctcgctcac accctcttcg cagcgagaat acgcggcggt
    15661 cggcggccga cccgtcgggg ctaccgcagg tcacctctac actggatcag tgactttcga
    15721 caatgcgcgg ggcagctcga cccctggcgg tccgccccgg acgcagccga acgtctctgc
    15781 gacaccctcg gtggtacaga gtttgcggac gcactccggt acttccgtgc cgttttccgt
    15841 cgagttcaat ccgccccggg acgcgcccgc cgaggcgcgg ctgtggcgcg cggtgcgcca
    15901 gttcgagcgg atgcatccgg cgttcgtctc gatgacctac ggcgcgggcg gctccacccg
    15961 cgaccgcacc gtgcgggtca ccggcgcgct ggcacaggag accaccctgc tgccggtggc
    16021 gcacctgacc gccgtggagc acagtgtggc tgagctgcgt tcactggtcg gttcctacgc
    16081 cgattccggg attcgcaaca tcctggtgct gcgcggcgat ccgccgggcg atccgctcgg
    16141 cgcctggcag cgtcatcccg aaggtgtcga gtacgccgag gaattggtgc gcatcgtgcg
    16201 cgatctcggt gacttccacg tcggcgtcgc ctcgttcccg cagggccatc accgctcgcc
    16261 cgacctcgac tccgacactg ccttcctgac cgcgaaactg cgtgcgggcg cggagtattc
    16321 gatcacgcag atgttcttcg acgtcgagca ctacctgcgg ttgcgcgatc gcgtgctgaa
    16381 gttcgacccg atcgagggcg ccaagccgat cattcccgag ctgatgccga tcacctcgct
    16441 gcgcacggtg gccagggccg aggaactctg cggccgcacg ctgccccccg cggtgctggc
    16501 gcgcttgcac cacgccgcgg gcgatgcccc cgacggcaac ccggccgcgg tccgcgaggc
    16561 aggcatcgag atcgccaccg agatggccca gcggctcatc gacgagggcg cgccctgcct
    16621 gcacttcatc accttgaatt tcgccaaggc gaccaccgag gtgctcacca acctcggcta
    16681 cggcgtcacc gccgcgccga tcagcgcctg acccgccgcg cccgcaggcg cgcggcgggc
    16741 gtccgctcac cagccggtgg tgccgctcag cgggacgttc acatagctcg gttccgccgg
    16801 atccagttgc aggtgttgcg gtttgaggcc ggtgccgtcg agcatcggcc ggatcggcag
    16861 ccccttcgga tagttgcccg cgaagacgtc gagccggagc cggtgtcccg gttggagtat
    16921 cgcgtcggtg ggcgcgaggc cgaggtcgag ttgcgtggcc tggccgggca cgacggtctg
    16981 ccgggcggcc agcgacatga ccgggaacgg atcggtgtag gccccgtcgg cggaccggcg
    17041 gctcctgccg tcgtcgacgg cgcgcatcga cgccatcagt tgtccggtgc tcaaggtgac
    17101 cgaacgtccg tccggcgcaa cgtcgttcag cgtcgcggtc cagtagccgt cggtggcgtc
    17161 gtgcacggtg ttcagatgta ccgcgatcgg tccggacagc gtcgtcggct cggtgaccgg
    17221 gggactggtg aaggtcaggc cggagacctc ctggatccgg gcgtccttgc cgcagccggt
    17281 gaagacgaga atgcctgcgg tgccctgggt tccgtcggcc gagcacaaac tcgccaggcc
    17341 gggcgcgacg gtcaggcggg cgttgtccgc ggtcgccgcg gtcacgagcg agccgtcgtg
    17401 cgcgctgagc gccgaggttc cgctcggcgc cgcggataga tacatccgcc ggtgctcggc
    17461 ctccgggcgc gggaactgct cggccgtggt ccagccaccg ccctgctgcc acatcgtcac
    17521 cgggccccac tgatcgatcc cgttgtcgat gcccttgagc cacttgtcga accaggcgcg
    17581 ctgcagcacg tcgatgcggg gcggctcgcc cggcttgccg cgcatgtcga agccggtgct
    17641 cacgtgatag ccgttgccca tcaccaactg tttctgcccg ggcggcaacg gaatgtcttg
    17701 gtagatgcgg ggttcgccgt tgacgaagtt gtcgtgccag ccgccgatca ccatcgtcgg
    17761 cacctggatc cgctcgggat ggccgagcca ggcctgccgg atcggactgt ccgggtcgag
    17821 cacgttgctc agttgcggcg gaatggtgtc gaaggaatcg gcggtcagcg tctgcagccc
    17881 gacgtcgagg aaggacaggg ggtcggcgag gcgatcggcc agccattgcg tgtcgaacct
    17941 gccctgtagc aacgacatca ggtccggcat gagtttggcc gcgttcacga ccagcaggta
    18001 gggcagcagg atgccgatgg ccgcgccacc cggcgcgatc atgtcgcgga ccagatcgtt
    18061 gcccggcacc accgggacga tggctttcag tgcgggcggc tgcttttcgg ccgcctgcac
    18121 ctggttgatg cccgagtagg acacgccgtt catcccgata ttgccgtccg accacggttg
    18181 ggccgcggcc caggcgatga cctccggggt gtccgactgg tctttcgggc cccagggttc
    18241 ccagttgcct tgcgagaagc cggtaccgcg cacgtccacc acgatctggg tgtagccgct
    18301 gcgaatcagg ttggggtcca ccgagaacac ccggccgaac ccgccgcccg cgacccgggt
    18361 cgcgtcggtc aggccctcca gcggcgtccc cggcaattcg aagtcgcgca gcaatccgac
    18421 caccgcgtcg gacaagaccg gcaccgacag cgcggtctgc aggaccatcg acccgagttt
    18481 cgtgtacggc gtcatgttca cgatggtcgg gaacggcgta tcgatcgggc cgtgcgcgtc
    18541 ggcgggccgg tacacgttcg ccttcaggac ggtcccgtcg ctcatcgtga tggggacgtc
    18601 ccagtcgata tggatggacg gaaaccgttg tggcccgtcg tgcagcgccg tccacgccgc
    18661 ggccccttcc ggcgtcgcgg caccgggcgc ggccacgacc acctgcgaaa ccgtaagcag
    18721 cgcaaccgct ccgacgaacc atcgggccca gcggcggcca agagcaatcc tcatcgatac
    18781 cctcctccat caaccggcag aaatatacat gcacgattgt atgtttcaag ggggtttccg
    18841 cttacgctcc catttaccgt cgggcgcacc gattcggtgc gcggttcttg tgcagcgcga
    18901 cggaactgcg ggcacggtgg cacctactcg gtagcgccgc cgcgcccgcg ctgcgcgtcg
    18961 gcttcaggcg gcgcgggcgg tgcgcaggcc ccaggcgtcg gcaaggaggc ggtgcgactc
    19021 cagcctgtcc tcgtggtgat gggtgacgct ggtgacgagc agttcgtcgg cgccggtgtg
    19081 ctgctgcagt gccgccaggc ggctcgtgac ggtgctcggc gagccgacga actgggtggc
    19141 gaggcgatcg tccaccagcc ggtgctgttc cggggtcagc ggcggcgtgg tggccgggtc
    19201 gagatagtcg gccgcgcccg cgccgctgcg gatgctgtgc acccagtgtc cataggtggc
    19261 ggcgtgctgc tgggcggttg cgtcgtccgc ggccaccacc acgtcggccg agaccaccac
    19321 atacggttcg gccagctgcg cggagggacg gaacgcgtcc cgataggctg cgaccgcgtc
    19381 cagcgcggtg cccggtgcga cgtgataggc cgccgcgaac ggcaacccga gccgcccggc
    19441 cagttcggcg ctctctccgg ccgaactgcc gaagacccac aactgtacct gtgcgccttc
    19501 gcccggaacg gcgtgcaggg caacgccttc ggggctgacg aagctgccgt ccagcagcgc
    19561 ccgcacctcg tcgacctgct cgtcgaacgg cggtgcctgc gcgccgcgct gttgcagcgc
    19621 actgatcgag gcgagaaatt tcgagcgatc ggtgatccgg ccggggtcga acgggggcgg
    19681 caccaccacg ccgtccctga tctcggtccg gccggtcgcg gtgtcgacgc gaggatgccc
    19741 acccttggga tgcgcgggct ccgaaccgta ttggctgcgg cggtggccgg agcggccgag
    19801 tccgagatcg agccggccag ggtagagcgc gtcgatcgtg ccgaacgcct ccacgatcga
    19861 ggccgaggtg tggtggccga cctgaaccgc cgccgagccc actcgaatac gcgaggtggc
    19921 cgccgcgacc aagccgatca gcgtgatcga ggcggaactg gccaccgaga cgaagtgatg
    19981 ctcggccagc caataccggt ggtagcccca ctgttccgcg cgctgcgcga gatcgacggt
    20041 gttgcgcagc gcctgctgcg cggtggaccc ggcgctgatc ggcgccaagt ccaggatgga
    20101 cagcgggacc gtcatgccgt cctccgctcc gatagctcgc cgtgcggcaa cccggggtgc
    20161 tgctcgcccg cttcgatggc cacccgcagc cggttctgct cgggcgccag cgggcaggtc
    20221 gcgaaatcgg tgaaggcgca gggcagattc gccgcccggt tgaagtcgag gcgcaccgtg
    20281 ccgtccgcct ccggcgcacc gactgccagc gagcgcgccg ccgggtaggt ggtgacgccg
    20341 ctggtggcat cggtgaacag cagtcgcaga tcggtcgggt caccgaacgc gagcacccgc
    20401 tcggtgaccg cgccgagcgt gaattcgatg gtgccggaag cagtgtggtg gtgttcgagt
    20461 ccgtcgacca ccgcgcccgt ggtcaccgtc tgcggctcgt cgagcggcgt gaacttaccg
    20521 ctcagcaccc agcgcgggtc cggcgcgtag ctcgggatgc cggtgaagct cagcagcgtg
    20581 ggcgcggccg ggtcgtgcac gcgcaccgcg tacagaccgg tgcggcggat cacctcgagt
    20641 acccgatcct cgtgccgcac agtgagtccc ggcgcgccct cggcgggcgt gatgatctgc
    20701 acgccggcga tccgctcgcc gtcgtagtcc agccggtcgg ccggttgcgc ggtgatgaac
    20761 accttgtcgt cggtcaccca ccaggtgccc ggcacgtccg gcagccgctc gggctgatcg
    20821 gtgagccagt gcagcgcggt caggctcagg aagccgagcg ggtcgcgcag ctggtcctcg
    20881 cgcgcgtgct gccactgtgc ccactcggtt tcgaaaacgg tgctgatgct ggtcgtcatg
    20941 acgctcgtgc tccttcgtgg gcggtggtgc ggtggtgggg atgacgcaga ccgaggtggt
    21001 cgcgcagggt ggtgccggtg tactcggtgc ggaaactgcc gcgctcctgc agttccggga
    21061 cgaccttgtc gacgaactcg tccagcccgc ccggggtgag atgcgggacg aggatgaaac
    21121 cgtcgctggc atcggcctgc acataggtgt cgatctgctc ggcgaccgcg gcgggcgtgc
    21181 cgacgaattg ctggcgcgcg gtcacctcga tgatcagctc acggatgctg aggttttcgg
    21241 ccgtcgcccg ggcccgccac gcctcggcga ccgcgcgcgg gtccttggcg tggcgcaccc
    21301 ggccgcgggt gatgtccgcg ttgtccgccg ggtcgacgtc gggcagtgga ccgtccgggt
    21361 cgtagccgga aaggtcacgg ccccagacct gttcgaggaa cgcgagcgcc gtctgtggcc
    21421 cgacctgctg ctgccggatg tggcgagcgc gctcctcggc gtcctgcgcg gagtcgccta
    21481 gcacgaacgt cgcggcgggc aggatcttca gttcgtccgg tgtccggccg tatttcgcga
    21541 gacggttctt gacgtcggtg tagaagcgct gcccggcctc cagcgtgccg tgcacggtga
    21601 agatcgcgtc cgcggccgcc gcgccgaact cgcggccgtc gtcggaatcg cccgcctgca
    21661 acagcaccgg gtgcccctgc gggctcggcg gcaggacgaa gcggcccgcg atatcgaatt
    21721 gcgaaccgcg atggcgggtt tcggggacct cccgggcgaa gacgccggcc gcccggtcga
    21781 cgacgagcgt gtccgcggcc cagctgtccc acagcttgcg ggtgacctcg acgacctcgg
    21841 ccgcgcgctg gtagcgcctg ctgtgctcca aatacccgcc gcgacggaag ttctcgccgg
    21901 tgaaggcgtc ggaggaggtg acgacgttcc aggcggcgcg tccgccggac agatgatcca
    21961 gggaggcgaa ttgcttggcc agctcgaagg gttcgttgta ggtgctgttg atcgtgcccg
    22021 cgagaccgag cttgccggtc accccggcca gcgcgtcgag caccgtgaag gtgtccggcc
    22081 tgcccaccac gtccaggtcg tggatgcgcc cgagatgttc gcgcaggcgc agtccttcgg
    22141 ccaggaagaa gaagtcgaac agcccgcgct cggcggtctg ggccaggtgc acgaacgagg
    22201 cgaaatcgac ctggctcttc gacgccgggt cggcccatac cgtggtgttg ttgacgccgg
    22261 ggaagtgcgc cgccaggtgg atgggcttgc gtggtttgcc ggtcacgacg ccaccccctc
    22321 gcgccctccg gtgacgtgca cagccgatcg ccgtacccgc gggcacgggt gcggcgatcg
    22381 gaccgcggat gcagcagagc tcatgcggaa gccccttcct tctcggtgta acggctgacg
    22441 ggacgggaca gtccgaggcg ggctcgtaat gtggtggagg acacagcggt acggcccagc
    22501 gcgggaaggt gccgcagggt cgcgggcact gccagcggac gcagcaccac cccgtcggcg
    22561 gctgccgagc ggtgcacggt ggcgagcaga tcgcgcagcg cggccgcggt gccgaggtgc
    22621 cggacaccgg tctcggcggg cggggcggcc cacccatcca gttcggccac ctccgcgctg
    22681 gccgcgtcgg ccgactcggc caggtgcacg tcgaggtcga gcagcacccg caccgcgtcg
    22741 gggtcgcgac cggccgctcg cagcgccgtg cgcagcgcgg tgcggtggct tcgcgccgcg
    22801 tccagaccgg ccgcggtgat gcggatcaga tcggcccttc gcacggcgac acctgtgctc
    22861 gggtcatcgt gcgcgcgcac cgcgacgatc gactgcccct gtggcgagcg cggcgtgatc
    22921 gagggcccct tcaccgcgaa gtggtcgccg gtgaagtcga tgtagtgcag cttgttccgg
    22981 tcgatgaagc ggccggtggg cacatcgcgg atctccgcgt cgtcctccca gctgtcccac
    23041 agccgggtga ccacctcgat cgcctcgtcc gcctcgtgcc acagcgatgc cgcgtcctgg
    23101 gcctgcttgc ggccgaaagc cctggcctgc tcctcgcctt cggagacggt gacctcccag
    23161 cccgcccggc cgagcgtggc gaaatccagg ctctggatgg ccttggccag atggaacggc
    23221 tcggtgtgcg tcacgggggc ctgcgggagc aggccgaggc gccgggtgcg cgcggcgacc
    23281 cgcgccgcga tcgccaccgc gtcgagcctg ccccgggtga caccggggcc gccgggctgc
    23341 aagccgaacg agtcgggcag gaaaaccgcg tcggcgccgg ccttttcgat cgcggtgacc
    23401 gcgtcgaccc agtacccgcc ggtgaacagc tcctcggccc gcgagtccgg ccgacgccag
    23461 gacgccgggt gcgctccggt gcccgcgagt tccaccgcga gaaagaagtc ggattcggtc
    23521 atcagcaggg tgccttccag tcgatgcact gccgcgccgc gggatgggtt ccggcgcagc
    23581 cgatgtcggg ggcgaagaag tacgcgtgct gccacagcgc ggtggcggcg gcgcgttgcg
    23641 ggggccgcaa ccgcgtgtgc caccagcgtt tcaccggtcc gggcggcggc tgggcgggct
    23701 ccggtcgact gcggcagtgg ggccggtgcc cggtgcggac gagtacccgg ctgtggcggt
    23761 aggtcggatc cggcatcagg cttgtccttt cgcgagcgcg ggagtgggga tggcggacaa
    23821 cagttcccgg gtgtattcgt gctgcgggtc gtcgaaaatc gccgcggtgg ggccggattc
    23881 gacgattcgc ccgtgtcgca tcaccgcgac gtggtcgctg atccggcgga ccaccgccag
    23941 atcgtgcgag atgaacaggt agctcagcgc cagttcggcc tgcagccggt ccagcagctc
    24001 caagatctgc gcctgcaccg aggcgtccag ggcggagacg ggttcgtcga gcaccagtag
    24061 atccggatgc agtgcgagcg cgcgggcgat cgcgacgcgc tggcgttggc cgccggacag
    24121 ttccgcgggc cggcgccggg cgaaactctc cggcagcgcc acctgcccga gcaactcggt
    24181 cacccgcgcc tgccgggccg cccggtcgcc gacgccgtag gcgcgcaacg gttcttcgat
    24241 gatcgtgccg acccgccacc ggggatccag tgacgcgtac gggttctggt acaccacctg
    24301 gaagcgctgg cggagggtgc gcagccgggt gccgcgcagc cgggtgagtt cgtggccgtc
    24361 gaaggtgacc cggccgctgt cgggatcggt gagccgcagc gcgattcgcg cggtggtcga
    24421 cttgcccgag ccggattcgc ccaccagcgc cagggtttcg ccgcggccga gctcgaaccc
    24481 caccccggcg accgcggtca ccgagccgcc ggcctgcgcg cgaaaacgct tgtgcacctc
    24541 gcgcaatgcg agcagcgggg cgccctcgcg cggcttgggc ggccggtacg cgcgcggcgg
    24601 ggccaggctc ggtgcggcgg cgagcagccg tttcgtgtac ggatgccggg gtgcggcgag
    24661 caccgtcgcg gtcggcccgc tctccacgat ctcgccgccg ctcagcacca cgagccgatc
    24721 cgcgcgttcc gcggcgacgg cgagatcgtg cgtgatcagc agcactgcgg tgccccgggc
    24781 gctgatctgc gcggccagct gatcgagcac ccggcgcgcc accgtggcgt ccagcgcact
    24841 ggtcggttcg tccgcgatca ccagttccgg ttcgcaagcc agcgcggacg cgatcagcac
    24901 ccgctgacgt tgcccgccgg acagttcgtg cggatactgc acctcgcgca gctccgggcg
    24961 gtccaacccg gcgtcggcca gcaattcgac cgcgcggacc cgggccgaac gccggtcggc
    25021 cagccgatgc accacgagcg cctcggccac ctgatcgccg acccggcgca ccgggttcag
    25081 cgacaaaccg ggatcctgtg gcacgaaacc gatccgggcg ccgcgcaggc ggcgtagcgc
    25141 ctgctccgat ccgagatcga cgagccggcc gccgaacgtc accgtgccgc cgctgatctc
    25201 ggcattgctc ccgagcagcc cgatcaccgc ctgcgcgagg gtggacttgc ccgaaccgga
    25261 ttcgccgacc agggcgacca cttcgccgcg cgccacgctc agcgagacac cggccagcgc
    25321 ggtcaccggg ccggtgtccg tccggtaccg gacccggaga ttgcgcacct gcaacagcgg
    25381 atctgcttcc cgccctgcgg gttcggcaca cgacacagcg cccggccggt cctcgacggt
    25441 tgccgtgcgg ggcgaagaag cggtggtcat gagttattcg ttccttcctg ccgcgcgccc
    25501 caggcgctgc gcagcgagca cgaccgcgac gatgaccagg c
//
