LOCUS       NC_018681              23474 bp    DNA     circular CON 21-MAR-2024
DEFINITION  Nocardia brasiliensis ATCC 700358, complete sequence.
ACCESSION   NC_018681
VERSION     NC_018681.1
KEYWORDS    RefSeq.
SOURCE      Nocardia brasiliensis ATCC 700358
  ORGANISM  Nocardia brasiliensis ATCC 700358
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Complete genome sequence of Nocardia brasiliensis HUJEG-1
  JOURNAL   J Bacteriol 194 (10), 2761-2762 (2012)
   PUBMED   22535940
REFERENCE   2  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-SEP-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
REFERENCE   3  (bases 1 to 9436348)
  AUTHORS   Vera-Cabrera,L., Ortiz-Lopez,R., Elizondo-Gonzalez,R.,
            Perez-Maya,A.A. and Ocampo-Candiani,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2012) Servicio de Dermatologia,Hospital
            Universitario 'Dr. Jose E. Gonzalez' and Centro de Investigacion y
            Desarrollo en Ciencias de la Salud, Universidad Autonoma de Nuevo
            Leon, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, Nuevo Leon
            64460, Mexico
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000250675.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 01:53:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,551
            CDSs (total)                      :: 8,489
            Genes (coding)                    :: 8,417
            CDSs (with protein)               :: 8,417
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 13 of 72
            Pseudo Genes (incomplete)         :: 63 of 72
            Pseudo Genes (internal stop)      :: 3 of 72
            Pseudo Genes (multiple problems)  :: 6 of 72
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:09:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1928294
            Orig. end                         :: 1951768
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP003876.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23474
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23474
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23474
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13474](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13474
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(497..508)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(765..1634)
                     /locus_tag="O3I_RS08585"
                     /old_locus_tag="O3I_008475"
     CDS             complement(765..1634)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (33-147). E-value:
                     1.2e-11. Score: 36.6. Matches aSDomain:
                     nrpspksdomains_O3I_RS08585_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019045550.1"
                     /locus_tag="O3I_RS08585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008475"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_014982513.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-08, bitscore: 33.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.9e-07, bitscore:
                     30.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHKLETSGATLTYDVHGPLPTADGRPPLLMIGLPMDASGFTAL
                     AAHFPDRTVVTYDPRGLGRSVRTDGEVDNLPAVHADDVHAVIEALDAGQVEVFASSGGA
                     IVALALVTAHPDDVTTLVAHEPPLLSVLPDAAAAERAADGYRAAYAEKGFGAGMATFIA
                     MTSWQGEYTDDYFAAPAADPATFGLPTEDDGARDHPLLSERSRPVVGYRPDIAALTAAP
                     TRIVLGYGDESIGTVTARTSLALADRLGHQPVLFPSHHGGFTGPESGYPGQPEAFAKVL
                     HEVLDPAN"
     aSDomain        complement(1194..1535)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_O3I_RS08585_Abhydrolase_1.1"
                     /evalue="1.20E-11"
                     /label="O3I_RS08585_Abhydrolase_1.1"
                     /locus_tag="O3I_RS08585"
                     /protein_end="147"
                     /protein_start="33"
                     /score="36.6"
                     /tool="antismash"
                     /translation="GLPMDASGFTALAAHFPDRTVVTYDPRGLGRSVRTDGEVDNLPAV
                     HADDVHAVIEALDAGQVEVFASSGGAIVALALVTAHPDDVTTLVAHEPPLLSVLPDAAA
                     AERAADGYRA"
     gene            complement(1705..3048)
                     /locus_tag="O3I_RS08590"
                     /old_locus_tag="O3I_008480"
     CDS             complement(1705..3048)
                     /GO_function="GO:0004806 - triglyceride lipase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016042 - lipid catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014988663.1"
                     /locus_tag="O3I_RS08590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008480"
                     /product="lipase family protein"
                     /protein_id="WP_237748270.1"
                     /transl_table=11
                     /translation="MLATALLYATHPGLAAPDPVIEAEPAVTLPPEFDEFYRPAADVVA
                     AAQPGQVLRARSITPAFLGFARLNIDAWQLLYRTTDSHGQAISTVTTVLVPRGPAPANG
                     RKLLSYQIAEDSAAQYCAPSYVLRSGAVPIEMVVAIESLIPIAAGIGQGWTVSLPDYEG
                     PNSAIGASRISAQATLDGIRATQSFHPAQLAGTATPTALWGYSGGTVPTSFAAEIAQDY
                     APELDIVGVAAGGIAAADFPAALRHNNNGAYTGLVGVAFAGLSNEYPEFRDVLRRELDP
                     LGQLFLGSKFIFCRAQGSALVPFYNFWGSYRGGDPLQNPVIQRVIADISLGQRTPDMPL
                     YIYHAQNDEILPNAGTDRLVDQYCRDGAPSVAYVRELLAEHISGTISHLPGAFYWLRDR
                     LDGVAAQPGCAITSPVTTVTDPLFTRAVVDLVPTALRALIGEAIGAGG"
     gene            complement(3230..4384)
                     /locus_tag="O3I_RS08595"
                     /old_locus_tag="O3I_008485"
     CDS             complement(3230..4384)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017984.4"
                     /locus_tag="O3I_RS08595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008485"
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="WP_014982515.1"
                     /transl_table=11
                     /translation="MNTIATTITAGQRRALLTHRQLRTAANAAETTAAVTASVLALHAT
                     DPATVYLSAAARLSAPQHETIEGQLYDRVNLLRMTAMRGTLFVVPRELAPVMLAALGRE
                     HAAGRMRALVRQLDSAGIAPDWVNGAMAELLAVLAEWGTATTAELTAAVDGLDRLFPTT
                     TRTRSSIGSWLLFVLAAQGRIVRADRVGGWTSIQHRWVLAPDLPDFPAAQARAELARHW
                     LTAFGPGTLADLQWWTGWKVTDTRVALADTGAVPVNLGDQPGFALPQHLSGLPEPEPVA
                     AVLPGLDPTPMGWRNRDFYLDPAHVPALFDGRGNIGPSLWWGGRIVGGWAQRRDGTLAW
                     QLLTDPGRAAQRAIAIEIDRLRDYLGDRRFTVAYRNPLERTLSG"
     misc_feature    complement(3533..3535)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4319..4321)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4431..4820)
                     /locus_tag="O3I_RS08600"
                     /old_locus_tag="O3I_008490"
     CDS             complement(4431..4820)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037170.4"
                     /locus_tag="O3I_RS08600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008490"
                     /product="VOC family protein"
                     /protein_id="WP_014982516.1"
                     /transl_table=11
                     /translation="MTAAISFTCVTVDAAHPPTLAAFYRDLLGWQIYHSDADYALVGDG
                     HTTLCFGAVERHTPARWPDDPEHPKRVHFDFSVEDVEQATARALDLGAILPEFQPGADP
                     EWAGHSPWTIVLDPEGTPICLNPRA"
     gene            complement(4830..5234)
                     /locus_tag="O3I_RS08605"
                     /old_locus_tag="O3I_008495"
     CDS             complement(4830..5234)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003944780.1"
                     /locus_tag="O3I_RS08605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008495"
                     /product="PPOX class F420-dependent oxidoreductase"
                     /protein_id="WP_014982517.1"
                     /transl_table=11
                     /translation="MSEQFLTLGDGKYVYLTHFRKDGTPVGLPIWVARDAERLVVWVEN
                     IDTWKVTRMRRNPQVTVASCDLRGHRRGPEVAARAEVLDVAGTDHVRKLIARKYGLPGR
                     AALWGNRLFRGKNTSVGIALYCAATPSNSE"
     misc_feature    complement(5224..5239)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.78"
                     /tool="antismash"
     gene            complement(5268..6179)
                     /locus_tag="O3I_RS08610"
                     /old_locus_tag="O3I_008500"
     CDS             complement(5268..6179)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="O3I_RS08610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008500"
                     /product="VOC family protein"
                     /protein_id="WP_081593928.1"
                     /transl_table=11
                     /translation="MNGRQRIAEDSARAGIAARIVVIALILIAGVAGCTSAPSGGPPPA
                     PSLAQVSLIDITSADIPRDRAFYERTFGWTLAADYPNYPILAAGKGPDIGLAMLGNPEA
                     GPLEPLYRIGQSLVFFGVSDIDAALQRAVALRGRVVQPATPISVGGSYAMFADPAGNVI
                     GLTQHATHPVTSSGAAGKPNPATLVAISTPDVAGTRSFYEQLFGLRLKERSPGYPILTS
                     GAGPDIGIARVDDPEAGPAVPLYQVGKPVVLLQTPDIDTSLKEVGQSGGTTFQSKVALP
                     SGGAYAFFTDPSGNTLGLLERP"
     gene            complement(6183..6566)
                     /locus_tag="O3I_RS42470"
                     /old_locus_tag="O3I_008505"
     CDS             complement(6183..6566)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="O3I_RS42470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="O3I_008505"
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="WP_014982519.1"
                     /transl_table=11
                     /translation="MQMRRVSPLMIVADTAATLAWYAERGFEVVRDLAPDDLHLLIKDG
                     EAFAQVMGAEVAHEFMPEKAGLPIGTMSGWIYLNLDDAAAFIASIEGRVEVVKDVDFDF
                     GRVFYFKDLNGYTVGVNQIQPLG"
     misc_feature    6627..6645
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.23"
                     /tool="antismash"
     gene            6662..7240
                     /locus_tag="O3I_RS08620"
                     /old_locus_tag="O3I_008510"
     CDS             6662..7240
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037009.4"
                     /locus_tag="O3I_RS08620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008510"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_014982520.1"
                     /transl_table=11
                     /translation="MNSQQPKRRRSASHRRDLLAAAGEQVIAERGVDGLTHRAVAEAAQ
                     VPLGSTTYYFADREDLLAAVLHRAVDGYTDYLDRWAAEHADDTLEQVVRYLIDIVLACV
                     TEQRGQSIVEFELCLAAARRPELQSAADRFNEAAVSALAPRFTDRITAVVASSTMSGYI
                     LHGLVRGTPPDRAEVTAVMYRVFGLPQPG"
     gene            7248..8450
                     /locus_tag="O3I_RS08625"
                     /old_locus_tag="O3I_008515"
     CDS             7248..8450
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024945.4"
                     /locus_tag="O3I_RS08625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008515"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_014982521.1"
                     /transl_table=11
                     /translation="MNARGTRQRLADRLRAELPEVARSMARAVLSTVPEYRKLPSDLLE
                     AELTHNAEAGLDLFLRAASELRAPNPAELAAALDNAIRRAAEGVPIEAVLIAQHRAIAS
                     GWDAVARLAIRPSERNQLLAAVPHLLATVAAIDVRIASRYLRERQKLRWEQQQRRRVLA
                     QAMLSGAPVGHLIERSGIELADQYRAVVFHVAEPTGPGRPRPESVLSHLRAEIEAVSRH
                     ALSRLERDGATTLFPAAVTETRLTGLVARLATVTGRRVVAGAAAHTELDGIAAAAETAT
                     ELARLAAVLHRPTGVYCIDDLALHYQLTRPGPARRWLAELLTPLATYPHLIEVLDACTT
                     YDFDRLAAAECLVVHRNTINYRLHRIAELTGYDPTDPDSAQLFAAAVLVRRLEALASRQ
                     V"
     gene            complement(8523..9734)
                     /locus_tag="O3I_RS08630"
                     /old_locus_tag="O3I_008520"
     CDS             complement(8523..9734)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016274.4"
                     /locus_tag="O3I_RS08630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008520"
                     /product="agmatine deiminase family protein"
                     /protein_id="WP_014982522.1"
                     /transl_table=11
                     /translation="MARLRFDYSANPWWKWRYTWWLAPELAAFYPAMTELRPPATAAAM
                     ARWLHRWRLLPPDVDVEAAAGEIARSAVPILDIPSAAPPSEHGAPLRLPAEWEPVERVL
                     VAWPYLFPGLWPFHRNLVRAIAATTPVTVIVPTPLFAAAVALQLPGQPVDYAVARLDDI
                     WIRDYGPLVGVDDAGRRVAVDTRYRPPPAIFTGYDDSFPGRWAGANKLGWRHLPLRLDG
                     GNLWSDGRGTILTTSLLFRRNRFRGRARVHELLSESFAVRNIIELPPLAGEFTGHVDLI
                     AKPADGETVLATEPGRGVNRARRQRIIEILRRAGYRVVELPYLPAYLNWQVPVWRSYTN
                     ALTSNGTVFLPLFDVAEADRAAVRAYQRAMPDHDIVGVPARVPAGSGGTIHCLTLQIPA
                     PSAR"
     misc_feature    complement(9456..9458)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9941..9959
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.83"
                     /tool="antismash"
     misc_feature    complement(9942..9960)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.71"
                     /tool="antismash"
     misc_feature    9950..9964
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.25"
                     /tool="antismash"
     gene            10001..11068
                     /locus_tag="O3I_RS08635"
                     /old_locus_tag="O3I_008525"
     CDS             10001..11068
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015354082.1"
                     /locus_tag="O3I_RS08635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008525"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_014982523.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.1e-57, bitscore:
                     192.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPSCVRFQVGGQPSRTDAPELDAGALLDAARQQVEPLLRAAV
                     DGLAAPLRRMAGYHFGWWDVEGRPTGSTQGKGLRAAVTFASARAWGADAAVAAPAAAAV
                     ELLHNFTLIHDDVMDGDQLRRGRATVWRVWGVGDAVLLGDALHALSTRVLIGSPDRVVV
                     RAVALLASTALDLCAGQHFDCACEHGGGVDVADYLLMASGKTGALLGAACALGGLYAGA
                     DDATVAALETYGRETGIAFQIIDDLLGIWGDAAITGKTPGNDLARRKRTLPIVAALESD
                     HPAAAELAGLYFDDRVLSKAELVRAAELVEQAGGMTAARQLAEQHRLAAMAALPSFMDL
                     SELSILGSTAVDRNR"
     gene            11091..12473
                     /locus_tag="O3I_RS08640"
                     /old_locus_tag="O3I_008530"
     CDS             11091..12473
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="O3I_RS08640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008530"
                     /product="cytochrome P450"
                     /protein_id="WP_014982524.1"
                     /sec_met_domain="p450 (E-value: 1.5e-76, bitscore: 256.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVFSRHRELPNGGLENQAIPTVPGALPMVGHSLALLRDPLAFI
                     SALPAYGDVTTVRIGSLPMVMVCDPLLTRQVLLEDSTYDKGGPVMDKAAEVIGDGLITC
                     PHSRHRRQRRLCQPAFRPDRLPEFGAVFASAAKEMASSWQDDQVVDVDRELMAMTAGTA
                     VLTMFAHTLPEPEQLIADLVTVVEGAFRRMITPRFLNHFALLGNRRFDQANKRLRSAVA
                     DAVGRRRADDADHSDLLAFLQEAVDSTEHPGSSDRLTDIELVDQITTFFGAGTETTAST
                     VAWALHLLARHPEIQDRLHQEIQDVLAGEPMTFERLTDMEMASHVINETLRLYPPAWLL
                     TRTVTKETLLGGFQLPAGTTLAYSPYVIHRRPDLYDDPDRFDPQRWRHTKPDRTAFIPF
                     AAGARKCIGDRVAVTQATMALITIVGQWRLTPLSDQALEPAVKATLTPRHLRLRVTARR
                     SL"
     misc_feature    11193..11195
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12509..13474
                     /locus_tag="O3I_RS08645"
                     /old_locus_tag="O3I_008535"
     CDS             12509..13474
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="O3I_RS08645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008535"
                     /product="terpene synthase"
                     /protein_id="WP_014982525.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-63, bitscore: 214.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDAGQAVEGLRIPFPSARNPRTELVRKPHRDWIDTMGIAPAAT
                     ADIGADLPLIIGRLYPHAGVDDLALVTDWNCWGFLYDDEFNGRLGTLPGAVAASVEGMI
                     EIICAPATFQEASEVPLTRALADMMRRFRGSASAIWFHRFSEHFAAGLTGFAHHAAARA
                     TGGSTSIEDYLAHRRLDIVSDPLLDFIELTDDCELSPVVHTSPEMLRLRRAALDIIIMI
                     NDVFSYEKELRCGDTENAVAVLERSTGLTHEDATARAIEIANQNILVLVEATETLPAAL
                     RKLDADLDQIDRALRFLTGIQTVVKATYDIHLESARYTAG"
     misc_feature    13492..13505
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.17"
                     /tool="antismash"
     gene            13530..14741
                     /locus_tag="O3I_RS08650"
                     /old_locus_tag="O3I_008540"
     CDS             13530..14741
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016882238.1"
                     /locus_tag="O3I_RS08650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008540"
                     /product="cytochrome P450"
                     /protein_id="WP_014982526.1"
                     /sec_met_domain="p450 (E-value: 1.9e-18, bitscore: 65.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVRSEARQYPMARGRCPFDPPPELGRRQREEPVSKVRIWDDGE
                     PWLFTRYADIRALLADPRVSADSARDGYPAQSPGIKAGPERAKLFITMDNPEHAAQRSL
                     LTADFTVRKIERLRPRIQQIVDDLIDDLLAGPKPADLVEAFALPVPSLVICELLGVPYA
                     DRAFFHRVSKVLTARYTPVAESLATMETLLDYLGGLVRDKLADPGDDLLSRLATEHISA
                     GAVTVAEAASMGLLLLVAGHETTANMIALGTAALLEHPDQLAAVRDGDDALVANAVEEL
                     LRYLTISHSGRRRVALEDMEVGGQRIRQGDGLITADSVANRDPARFPDPDRLDVTREAR
                     HHLAFGYGIHQCLGQALARVELQVAYRTLYRRIPTLRLAVALDEVEFKDDMVVYGVHEL
                     PVTW"
     tRNA            complement(15089..15165)
                     /anticodon=(pos:complement(1943423..1943425),aa:Arg,
                     seq:tct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="O3I_RS08655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="O3I_0t42211"
                     /product="tRNA-Arg"
     gene            complement(15089..15165)
                     /locus_tag="O3I_RS08655"
                     /old_locus_tag="O3I_0t42211"
     gene            complement(15235..15621)
                     /locus_tag="O3I_RS08660"
                     /old_locus_tag="O3I_008545"
     CDS             complement(15235..15621)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005264310.1"
                     /locus_tag="O3I_RS08660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008545"
                     /product="DUF4345 family protein"
                     /protein_id="WP_014982527.1"
                     /transl_table=11
                     /translation="MSVVSIVLIALVALFFAAMGVFGLLRPSQLVDPLGLLADRADARA
                     EVRAVYGGFGIAIAVILGLAAADVGDLRFGACVAVAAALGGMAFGRVWSSVVESPSAFY
                     PVWFYLVLEVILAAMLVLAVALDP"
     misc_feature    complement(15547..15549)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15596..15610
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     gene            15704..17761
                     /locus_tag="O3I_RS08665"
                     /old_locus_tag="O3I_008550"
     CDS             15704..17761
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011207832.1"
                     /locus_tag="O3I_RS08665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008550"
                     /product="cytochrome c oxidase assembly protein"
                     /protein_id="WP_014982528.1"
                     /transl_table=11
                     /translation="MSSALDPSASPDLESNRPAATYAVVIALSAAIAAMVAALVVGLSA
                     AQALSLLGIPDPGALTTYGLPAVRALADLSAALTVGSLLFAAFMVPPQASGLLDVGGYR
                     AMRRASNFALLWACCAALLIPLTVSDTTGQPVRDTLDPVGLWRAIDQIELAGAWRTTVL
                     FALIVAVGARLALRWGWTPVLFGAAIATMMPLALTGHSSSGGAHDVATNSLILHLVSAA
                     VWVGGLFALLAHARRGGAHTDLAARRFSLTATFAFVTIGVSGVINSWVRVPWDELFTST
                     YGRLVLAKAAALVLLGLFGYAQRRAALPALAADPKDRGALIRFAGVEVLVFAATMGLAV
                     GLGRTPPPPPTSIPTPAEVELGYNLAGPPTVARMLFDWRFDLIFGTLAIVLAIGYLLGV
                     RRLRARGDAWPIGRTIAWLSGCVVLLLATSSGVGRYAPAMFSVHMGAHMALSMLAPILF
                     ALGGVVTLALRALPPAGRGGAPGPREWILAAVHNPVSRFLTHPIVASVIFVGGFYALYL
                     GGIFDTFADSHGAHLLMNLHFLLSGYLFYWVVIGIDPKPRQVEPLTKLAMVFGSLPFHA
                     FFGIALMSMTTVLGGWFYRGLGLGWNGDLLGDQRTGGSLAWASGEVPLVVVMLALLIQW
                     SRSDKRLAQRTDRAADRDHDADLAAHNAMFAELAKRDRGTQKSAGDPAQP"
     gene            17928..18881
                     /locus_tag="O3I_RS08670"
                     /old_locus_tag="O3I_008555"
     CDS             17928..18881
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928851.1"
                     /locus_tag="O3I_RS08670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008555"
                     /product="serine/threonine dehydratase"
                     /protein_id="WP_041563547.1"
                     /sec_met_domain="PALP (E-value: 4.9e-56, bitscore: 189.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVFPEHDHIDRVHRSDVRAARKRLAGRTRKTPVFHTSVAGPDGPV
                     PVTMKLEYLQYGGTFKVRGSLNALLAAPDCAEQVVIASGGNAGIAAALAAAQLGKSCTV
                     VVPESAPHTKVAAMWSHGAEVLWHGTTYTEALDYATELAVERKALRLHAYDLAAVVAGA
                     GVVGLELEEQVRGRPPVLAAVGGGGLIAGIAAAIGRRQQIIGVEPEGIPTLHAALAANR
                     PVEIAVSSIVAESLGATRIGDIAMDVARRHEIRSLLVTDDAITTARDYLWREFRIVVEL
                     AGAVALAAVQSGVYVPAPGERPVIVLCGANTDLAAL"
     misc_feature    19168..19184
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            19283..19777
                     /locus_tag="O3I_RS08675"
                     /old_locus_tag="O3I_008560"
     CDS             19283..19777
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928850.1"
                     /locus_tag="O3I_RS08675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008560"
                     /product="single-stranded DNA-binding protein"
                     /protein_id="WP_014982530.1"
                     /transl_table=11
                     /translation="MYEANTTVIGTIVNNPVKRDLPNGEQMLTFRMASNSRRLDHATGE
                     WVDNGALFLTVSCWRRLVSGVDVSLHRGDPVLAHGQLRSREYRGRDGVERRDLEMRATA
                     VGPDLARCTAQVTRWSADRWTDDQPPQEFSVTESGVLSGALPPTQPPQLVTADEAVPTP
                     V"
     gene            19963..20658
                     /locus_tag="O3I_RS08680"
                     /old_locus_tag="O3I_008565"
     CDS             19963..20658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015626322.1"
                     /locus_tag="O3I_RS08680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008565"
                     /product="DUF4433 domain-containing protein"
                     /protein_id="WP_014982531.1"
                     /transl_table=11
                     /translation="MDLAYIPASGFMSCGGGAPLREHPRDWLAWHFTHAGNLGRIASEK
                     ALLPASAVTPKVNVANPGVKQRRAQIVVRPDSEYPACYVNEHVPFYIAAKSPMLYVVNR
                     GHADYSGGSDDLVLLGFVLGNLAVSGSLWCATDQNAATSTVGFSRKLDDLGHFVDFDLL
                     CQRDWYNTPDDQNRMSRRAAEVLVKDRFDLRLVQVVIAKKASALEVAKVAFQDVGGVRE
                     YHVVPEMFY"
     misc_feature    20329..20331
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20672..21742
                     /locus_tag="O3I_RS43640"
                     /old_locus_tag="O3I_008570"
     CDS             20672..21742
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019513426.1"
                     /locus_tag="O3I_RS43640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="O3I_008570"
                     /product="macro domain-containing protein"
                     /protein_id="WP_014982532.1"
                     /transl_table=11
                     /translation="MVVEQASGDLLAADAEALVNTVNCVGVMGKGIALQFKRRFPSVFK
                     EYEAACRRGDVQIGRMFVSPIEQLDGARWVINFPTKRHWRSPSKLEYIESGLDDLKRVL
                     IEYEINSVAIPPLGAGNGGLSWADVEPLIRRKLSGMEGIRVLLFSPSSVQRPVAAPEHI
                     NMTWGRALVVSLIGSYVAQRAIAEPWEDQHGASHLEIQKLMYFAELLEPRLKLDFSQGR
                     YGPYSERVRHLLQGMEGAYVTGLGDGACRVLDLSPIAPTERGYSEAKMFLANGDYDQVY
                     SVIDRVMSWIEGFEGPYGVELLASADWVARHHRASDATKAAEVVRKWTERKGRLFTDEH
                     VASALGHLKAVGALQG"
     misc_feature    21065..21067
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(22331..22342)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
ORIGIN
        1 tgcgcccggc gaagccgacg cgtaacccgc ccgcactcga cctcgaccag atcgtggtca
       61 ccgctgttgc gctgctcgat gcggagtcgg tgtccggtct gaccatgcgc aagctcgcgg
      121 cccggctcga cgccgcgccg atgacgctgt acggatatgt ggccaccaaa gaagatttgc
      181 tggaactcgc ggtcgacgcg gtgttcgcgg aggcgctcgc ggccgacccg gcggcagacg
      241 actggcgagc cgcgctaacc gcgatcggcc accacacctt ccaggcgttg gtgcgccatc
      301 cgtgggccgc agccctggtc ggtgccaacc cgccactggg cccggcggcc gtcgcgcaat
      361 tcggcacgat cctgcgggtg ctgaccgccg cgggtttcac cggtggccac ctggattcgg
      421 cgctgacggg tttctactac tacgtgctcg gcgccgcgct cgccgaatcc ccttgggccc
      481 gcgccggtcg agcggcgagt tcgtttaccg cggccgacat ttcgcggttg acctcagccg
      541 acgggcaaga tgtcacgccg gtcgccgcct acttcgaacg ttatccgaac accgatccgg
      601 tccaacgttt cggccacggc ctgcgcgccg tcctcaacgg tctcgatccc gcctgaagct
      661 ctgccgcagg agccgggtgc gccgatgcgg tacccggtcc gcgggtttct gctgagacca
      721 gtcctcgagt ggctcaacgg ttctcgacca tcgggaacgc tcgatcagtt ggccgggtcg
      781 aggacttcgt ggaggacctt ggcgaacgcc tcgggctgac ccgggtagcc ggactcggga
      841 ccggtgaatc cgccgtgatg gctcgggaac agcacaggct ggtggccgag ccggtcggcg
      901 agcgccaacg aggtgcgggc ggtgaccgtg ccgatcgact catcgccata gccgaggacg
      961 atccgcgtcg gcgccgcggt gagcgcggcg atgtcggggc ggtagccgac gaccggacgg
     1021 gaacgttccg acagcagcgg gtggtcgcgg gcgccgtcgt cctcggtcgg caggccgaac
     1081 gtcgcgggat cggcggcggg cgcggcgaaa tagtcgtcgg tgtattcgcc ctgccaggag
     1141 gtcatcgcga tgaaggtagc catgcccgcg ccgaaacctt tttccgcgta ggcggcgcgg
     1201 tacccgtccg ccgcgcgttc ggccgcggcg gcatcgggga gcaccgacag cagcggcggt
     1261 tcgtgcgcca ccaacgtggt cacgtcgtcg gggtgcgcgg tcacgagcgc cagtgcgacg
     1321 atggccccgc cactgctggc gaagacctcg acctggccgg cgtcgagcgc ctcgatgacg
     1381 gcgtgcacgt cgtcggcgtg gacagcgggg aggttgtcga cctcgccgtc ggtgcgcacg
     1441 ctgcgaccga gcccgcgcgg atcgtaggtg accaccgtac ggtccgggaa atgcgcggcg
     1501 agcgcggtga aaccgctggc gtccatcggg aggccgatca tcagcagcgg cggccgcccg
     1561 tccgcggtcg ggagcggtcc gtggacatcg taagtgagcg tcgcgccgga ggtttcgagc
     1621 ttgtgtgtcg tcatgccggt ttcgacggta ccggagccga gaactcatcg gtgggtgcta
     1681 gatctccgtg agcgggtctt gcggctaccc gccggcaccg atcgcttcgc cgatcagcgc
     1741 gcgcagcgcg gttggcacga gatcaactac ggctcgggtg aatagggggt cggtgacggt
     1801 ggtgacgggg ctggtgatgg cgcatccggg ttgcgcggct acgccgtcga gccggtcgcg
     1861 cagccaatag aaggccccgg gtagatggga gatggtgccg gagatgtgct cggccagcag
     1921 ttctcgcaca tacgcgacgc tgggcgcccc gtctcggcag tactggtcga cgagccggtc
     1981 ggtgcccgcg ttaggcagaa tctcgtcgtt ctgcgcgtga tagatgtaga gcggcatgtc
     2041 gggagtgcgc tgccccagcg agatatcggc gatgacacgc tggatcacgg ggttctgcaa
     2101 cggatctcca ccccggtatg agccccagaa gttgtagaac ggaaccagtg ctgaaccttg
     2161 agcgcggcag aagatgaact tcgagccgag gaacaactgc cccagcggat ccagctcccg
     2221 gcgcaacacg tcacggaact ccggatactc gttgctcagc ccggcgaagg ccacgccgac
     2281 gaggccggtg taggccccgt tgttgttgtg gcgcaatgcc gccggaaaat ccgccgcggc
     2341 gatgccgcct gcggccacgc cgacgatgtc gagttcgggc gcgtagtcct gggcgatctc
     2401 ggcagcgaac gaggtgggaa cggtgccccc ggaatagccc cacagtgcgg tcggcgtcgc
     2461 agtgcctgcc agctgagcgg ggtggaaaga ctgggtcgcg cggatgccgt ccagtgtggc
     2521 ctgcgcgctg atccgggagg ccccgatcgc tgaattgggt ccctcgtagt cgggcagcga
     2581 aaccgtccag ccctggccga tgcccgccgc gatcgggatc agcgattcga tcgcgacgac
     2641 catctcgatc ggcacggcac cgctgcgcag gacgtaggag ggtgcacagt attgggcggc
     2701 actgtcctcg gcgatctgat aggacaacag ttttcgtccg ttcgctggtg ccgggcctcg
     2761 cggaacgagc acggtggtca ccgtcgagat cgcctggccg tggctgtcgg tggtgcggta
     2821 gagcagttgc cacgcgtcga tgttcagccg tgcgaagccg agaaaagccg gtgtgatcga
     2881 tcgggctcgc agcacttggc ctggctgggc ggcggcgacc acatccgcag ccggacggta
     2941 gaattcgtcg aactccggcg gaagcgtcac ggcgggttcg gcctcgatta ccgggtccgg
     3001 tgcggcgagt cccgggtgcg tggcgtacag cagcgctgtc gccaacaaga ccactccgta
     3061 ccgaattctt ccacgctgcc gcatcgcgcc ctcatctcga ttccgccccg cgggccggtc
     3121 accggcggtg gcgtctgtgc agagcacgat cgcaaggagc tgtcgtggtc gtcactgggc
     3181 ggtggcgcag ggttggtgcg cgttgtttgt gcacccgaca gggccgcgcc tatccgctga
     3241 gcgtgcgttc gagcggattg cggtaggcga cggtgaaccg gcgatcgccc aaatagtctc
     3301 tgagccggtc gatttcgatc gcgatggcgc gctgtgctgc gcgacctggg tcggtcagga
     3361 gctgccaggc cagagtgccg tcgcgacgtt gtgcccaacc gccgacgatg cggccgcccc
     3421 accacagcga aggtccgatg ttgccccgtc catcgaagag cgcgggcaca tgcgcaggat
     3481 cgaggtagaa gtctcggttg cgccagccca tcggggtcgg atccagtccg ggtaacaccg
     3541 ccgccaccgg ctccggctcg ggtagccccg aaagatgctg ggggagggcg aaacccggtt
     3601 ggtcaccgag gtttaccggg acggccccgg tgtcggcgag ggcgacccgg gtgtcggtga
     3661 ccttccatcc ggtccaccac tgcagatcgg cgagggtgcc gggcccgaaa gcggtcagcc
     3721 agtgtcgcgc gagttcggcg cgtgcctgtg ccgccggaaa gtcgggcagg tcaggggcga
     3781 gcacccagcg gtgctggata ctcgtccaac cgccgacccg gtcggcgcgc acgatacgtc
     3841 cctgtgcggc aaggacgaac agcaaccagg atccgatgct gctgcgggtg cgcgtggtgg
     3901 tggggaagag ccgatccaac ccgtcgacgg ccgccgtgag ttccgcggtg gtggcagtgc
     3961 cccattcggc cagcacggcg agcagctcag ccattgctcc gttcacccag tcgggcgcga
     4021 tcccggcgga atccaactgc cgcaccaagg ctcgcatcct gcctgcggcg tgttcgcggc
     4081 cgagggcggc gagcatgacc ggcgccagct cgcgggggac gacgaacaga gtgccgcgca
     4141 tcgccgtcat tcgcagcagg ttcacgcggt catacagctg gccctcgatg gtctcgtgct
     4201 gcggagcaga cagacgcgcg gcggccgaca gataaaccgt ggcagggtcg gtggcatgca
     4261 gagcgagcac ggatgcggtt accgcggcgg tggtttcggc ggcattggct gccgtgcgta
     4321 actgccggtg cgtcagtaga gcgcggcgtt gtccggcggt gatggtcgtc gcaatggtgt
     4381 tcatggacag gatctttcat atcgttgtca gaagagaatg agcggtttgg tcaggctcgt
     4441 gggttgaggc agatcggcgt gccctcggga tcgagcacga tggtccaagg ggaatgcccg
     4501 gcccactccg gatccgcgcc gggctggaat tccggcagga tggcgccgag gtccagcgcg
     4561 cgagcggtcg cctgttcgac atcctcgacg ctgaaatcga agtggacgcg cttgggatgt
     4621 tcgggatcgt cgggccagcg cgcgggcgta tgccgctcta ccgcaccgaa acacagcgtc
     4681 gtgtgcccgt cgccgaccag cgcgtagtcg gcgtcgctgt gatagatctg ccatccgagc
     4741 aaatcacggt agaaggcggc caaggtgggt gggtgggcgg catcgacggt gacgcaggtg
     4801 aacgagatcg cggcagtcat gagggggtcc tattccgaat tcgagggggt ggcggcgcaa
     4861 tacagtgcga tgccgacgga ggtgttcttg ccgcggaaga gccggttccc ccagagcgcg
     4921 gctcgcccgg ggagaccgta cttgcgagcg atcagcttcc ggacgtggtc ggtgcccgcc
     4981 acatcgagca cctcggcccg cgcggcgact tccggcccgc gccggtgccc gcgcaggtcg
     5041 caggaggcga ccgtgacctg gggattgcgg cgcattcgtg tgaccttcca ggtatcgatg
     5101 ttctccaccc acaccacgag tcgctcggcg tcccgggcga cccagatcgg cagtccgacc
     5161 ggtgtgccgt ccttgcgaaa gtgggtgaga tatacgtact ttccgtcgcc gagcgtgaga
     5221 aattgttcgg acacagcgtt actcccgtcg atgccgatgg tgctgattca tggccgttcg
     5281 agcagtccga gggtgttgcc actgggatcg gtgaagaacg catacgcgcc accggagggc
     5341 agcgccacct tggactggaa tgttgttccg ccggactgcc cgacctcttt caggctggtg
     5401 tcgatatccg gggtttgcag caacaccacc ggtttcccga cctgatacag cggtacggcc
     5461 ggtcccgcct ccggatcgtc gacgcgggcg ataccgatat caggacctgc gccgctggtc
     5521 aggatcggat aaccgggcga gcgctccttc aggcgtagtc cgaacagctg ctcatagaac
     5581 gagcgggtac ccgcgacatc cggcgtcgaa atcgccacca gggtcgcagg attcggctta
     5641 cccgccgcgc cggaggaggt caccggatgg gtggcgtgct gagtcaggcc gatgacattg
     5701 ccggccggat cggcgaacat cgcgtaggaa ccaccgaccg agatcggcgt ggccggctgg
     5761 acgacgcgcc cgcgcagcgc gactgctcgc tggagggcgg cgtcgatatc ggagaccccg
     5821 aagaacacca ggctctggcc gatgcgatac agcggttcga gcggtccggc ctccgggttg
     5881 cccagcatcg cgaggccgat atccggcccc ttgcccgcgg ccaggatcgg atagttcgga
     5941 tagtccgccg ccagcgtcca gccgaaggtt cgctcataga acgcgcggtc gcgcgggata
     6001 tcggccgagg tgatatcgat caagctcacc tgtgccaggg acggtgccgg tggcggcccg
     6061 cccgagggcg cactcgtgca acctgccacc ccggcgatca agatcagcgc gatgaccacg
     6121 atccgggcag ctatgcccgc acgcgccgaa tcttcggcaa tcctttggcg accgttcatc
     6181 ggtcacccca gcggttggat ctggttgacg ccgacggtgt agccgttgag gtccttgaag
     6241 tagaacacgc gaccgaagtc gaaatcgacg tccttgacca cctctacccg gccctcgatg
     6301 gacgcgatga acgccgcggc gtcgtcgagg ttgagataga tccagcccga catcgtcccg
     6361 atcggtagcc ctgccttctc cggcatgaac tcatgcgcca cctccgctcc catcacctgg
     6421 gcgaatgcct cgccgtcctt gatcagcagg tggagatcat cgggtgccag atcgcgcacc
     6481 acctcgaagc cgcgctcggc gtaccacgcc agcgtggcag cggtgtccgc cacgatcatc
     6541 aatgggctca cgcgacgcat ctgcatagct gcttccttcc gtccgagtgt cggcgcgcag
     6601 gtgcgccgaa cgatagtgta caaacatatt gtacaaattt ataggtatca gatggagttc
     6661 agtgaatagt cagcaaccga agcggcgacg gtccgcgtcc catcgtcgtg acctgctcgc
     6721 cgcggccggg gaacaagtga tcgccgagcg cggagtggac ggattgaccc atcgcgcggt
     6781 cgcggaggcc gcgcaggtcc cactcggctc gaccacctac tacttcgccg accgggaaga
     6841 cctgctcgcg gcggtactgc accgggcggt cgacgggtac accgactacc tggaccggtg
     6901 ggctgccgag catgccgacg acacgctcga acaggtcgtg cgctacctga tcgacatcgt
     6961 gctggcctgc gtcaccgagc agcgggggca gagcatcgtc gaattcgaac tgtgcctggc
     7021 cgcggcacga cggccggaat tgcagtccgc ggccgatcgc ttcaacgagg cggcggtgag
     7081 cgcgctcgcc ccgcgtttca ccgaccggat caccgccgtc gtggccagca gcacgatgag
     7141 cggttacatc ctgcacggcc tggtccgcgg caccccgccc gatcgcgccg aggtcaccgc
     7201 ggtcatgtac cgcgtcttcg gtctaccgca gcccggctag gagaccgatg aacgcacgcg
     7261 gcacccgcca acgactcgcc gaccggttgc gcgcagagct gccggaggtc gcccggtcga
     7321 tggcgcgggc ggtgctcagc accgttccgg aataccggaa gctgccgagt gacctgctcg
     7381 aagcggagct gacccacaac gcggaggcgg gactcgacct attcctccgc gcggcaagtg
     7441 aattgcgcgc acccaaccca gcggaactgg ctgcggcact ggacaacgcg attcgccgtg
     7501 cggcggaggg tgtcccgatc gaagcggtgc tcatcgcaca gcatcgcgcg atcgcgagcg
     7561 gctgggacgc ggtggcgcgc ttggcgatac ggccgtccga gcgcaaccaa ctgctcgccg
     7621 ccgtaccgca tctgctggcc acggtcgcgg cgatcgatgt ccggattgcg agcaggtatc
     7681 tgcgcgaacg ccagaaactt cggtgggagc agcagcaacg ccggcgggtg ctcgcgcagg
     7741 ccatgctgtc cggcgcgccg gtgggccatc tgatcgaacg ctcggggatc gagctggccg
     7801 atcagtatcg ggcggtcgta ttccatgtgg ccgagccgac cggccccggg cggccacgac
     7861 ctgaatcggt gctgtcccac ctccgtgccg agatcgaggc ggtctcgcgc cacgcgttga
     7921 gcaggctcga acgcgacggt gctacaacgc ttttccccgc cgccgtgacc gaaacacggc
     7981 tcaccgggct cgtcgcgcga ctggcgaccg tgaccggtcg tcgcgtcgtg gcgggagccg
     8041 cggcccacac cgagctggac gggatagccg ccgcggccga gacggcaacc gagctcgcac
     8101 gcttggctgc cgtgctccac cggcctaccg gcgtctattg catcgatgac ctcgcgttgc
     8161 actaccaact gacccggccg ggccctgctc gccgctggct ggccgagttg ctcacgccgc
     8221 tcgccaccta cccgcacctc atcgaggttc tcgatgcctg cacgacctat gacttcgatc
     8281 ggctcgccgc cgctgaatgc cttgtggtgc accgcaatac gatcaactat cggcttcacc
     8341 gaattgccga actgaccggc tatgatccga ccgatcccga cagcgcccaa ctcttcgcgg
     8401 ccgccgtgct cgtccgccgg ctcgaggcat tggcatcacg ccaggtgtga atgttcgccg
     8461 gctgtcgaag ccgattgtga cggcgctgat caggaggctg caaggacgca ccacatcgtc
     8521 gctcagcgcg cgctcggtgc gggtatttgc agggtgaggc agtggatggt gccgccggag
     8581 ccggcgggga ctcgggcggg cacgccgacg atgtcgtgat cgggcatggc ccgctggtag
     8641 gcgcgtaccg cggctcgatc tgcctccgct acgtcgaaca agggcaggaa aaccgtaccg
     8701 ttgctggtga gagcgttggt gtaggaacgc cacaccggca cttgccagtt cagatacgcc
     8761 ggtagataag gcagttcgac gacgcggtaa ccggcgcgtc ggagtatctc gataattcgt
     8821 tggcggcgag cacgattgac gccgcggccg ggctcggtgg ccagcactgt ttcgccatcg
     8881 gcgggtttgg cgatcaggtc gacgtggccg gtgaattcgc cggccagggg cggcaattcg
     8941 atgatgttgc gcactgcgaa gctctcgctc agcaactcgt gtacccgggc acgaccgcgg
     9001 aagcggttgc ggcggaacag cagtgaagtg gtgagtattg tgcctcggcc gtcggaccag
     9061 agattgccgc cgtcgagccg cagtggcagg tgacgccagc ccagcttgtt cgcgcctgcc
     9121 cagcggcccg ggaagctgtc gtcgtatccg gtgaatatgg cgggcggggg ccgatagcgg
     9181 gtgtccaccg cgacccgtcg accggcgtcg tccaccccga cgagcgggcc gtagtcgcgg
     9241 atccagatat cgtcgagccg tgcgaccgcg tagtcgacag gttgcccggg cagctgcagc
     9301 gcgacggcag cggcgaacag cggggtaggc acgatcaccg tcacgggggt ggtcgccgcg
     9361 atcgcgcgga ccagatttcg atgaaacggc cacaaccccg gaaacaggta gggccacgcc
     9421 accagcaccc gctccaccgg ctcccactcg gcaggtaacc gcaacggcgc gccgtgctcc
     9481 gaaggcggtg cggcggaagg tatgtcgaga atcgggaccg cggaccgggc gatctcgccg
     9541 gccgcagcct cgacatcgac atccggcggt agcaaccgcc accgatgcag ccaccgagcc
     9601 atcgccgcgg ccgtcgccgg tggtcgcagt tcggtcatcg cgggatagaa cgcggcgagt
     9661 tccggggcca gccaccaggt gtagcgccac ttccaccatg gattggccga gtaatcgaaa
     9721 cgaagacgtg ccatcggcga tccccctgac tccccacccc gatcttacgt ggtagccacc
     9781 acttccacgt cgaagctgcc ggtcgacgtg gtcttcgggt agcagcgaca ccatgccgag
     9841 aggctccgga cgtcggttat gtccggagtg tctctatcgc gtccggggcc tcggttgcgt
     9901 ttgtctcatt caccttgaca actcctaccg tgagggcaac gattggattt atctccagtc
     9961 aattcatttg acctatgatg agtcacgata ggaaatcgat atgaccgcgg tgccgtcgtg
    10021 tgtgcgtttt caggtgggcg ggcagccttc tcggactgac gcaccggaat tggatgcggg
    10081 cgcgctcctc gacgccgcac gccaacaggt cgagccgctg ttgcgtgcgg cagtagacgg
    10141 gctagcggcc ccgctgcgac gaatggccgg atatcacttc gggtggtggg atgtcgaggg
    10201 ccgtcctacc ggctcgaccc aggggaaggg gttgcgtgcc gcggtgactt tcgcctcggc
    10261 gcgagcgtgg ggggccgatg ccgcggtggc ggcgccggct gcggcagcgg tggagctgct
    10321 gcacaatttc acgctgattc atgacgatgt gatggatggc gaccagctgc gtcgtggccg
    10381 ggcgacggtg tggcgcgtat ggggtgtcgg tgacgccgtg cttctgggtg atgcgttgca
    10441 tgccttgtcg actcgcgtcc tcatcggcag tccggaccgt gtggtggtcc gagcggttgc
    10501 gctgctggcc tcgacggccc tggacctgtg cgcgggtcaa catttcgact gcgcctgcga
    10561 gcacggcggt ggggtcgatg tcgccgacta cctgctgatg gcgtccggca agaccggcgc
    10621 gctgctcggg gccgcgtgtg cgctgggcgg gttgtacgcc ggggccgacg atgccaccgt
    10681 ggcggcgttg gaaacctatg gccgggagac aggcatcgca ttccaaatca tcgacgacct
    10741 gctgggcatc tggggcgatg cggcaattac cggaaaaaca cctggcaacg atctcgctcg
    10801 gcgaaaacga acccttccga ttgtcgcggc gctcgaatcg gaccatcccg cggcagccga
    10861 gctggcaggt ctgtatttcg atgaccgagt gctgagcaag gccgaattgg ttcgtgctgc
    10921 cgagttggtc gagcaagcgg gcggaatgac tgcggcacgg caactggccg agcagcatcg
    10981 actcgcggcc atggcggcac tgcccagttt tatggacctg tccgagctga gcattcttgg
    11041 ttcgacggct gtcgaccgca accgataatt caataggagt ccgagtcact atgcgagcag
    11101 tattcagccg gcaccgagaa ctgccgaacg gcggtttgga aaatcaggcg attccgactg
    11161 ttccgggagc gctgccgatg gtcgggcatt cgttagcgct gctgcgggac ccgttggcgt
    11221 tcatctcggc acttcccgca tacggcgatg tgacgacggt gcgaatcggg tcccttccga
    11281 tggtgatggt gtgcgatccg ctgctcaccc ggcaggttct gttggaggac agcacctacg
    11341 acaagggcgg accggtcatg gacaaagctg ccgaggtgat cggtgatggt ttgatcacct
    11401 gcccgcacag caggcatcga cggcagcgtc ggctgtgcca gccggcgttt cgtccggacc
    11461 ggctccccga attcggcgcg gtgttcgcgt ccgcggcgaa agaaatggcg agttcctggc
    11521 aggacgacca agtcgtcgat gtcgacagag aattgatggc aatgacagca ggcacggccg
    11581 tgctgacaat gttcgcccac accctgccgg agccggaaca gctcatcgcc gacttggtca
    11641 cggtggtgga gggagcgttc cggcgaatga tcacaccccg gttcctcaac cacttcgcgt
    11701 tgctgggaaa ccggcgcttc gaccaggcca acaagcggtt gcggagtgcg gtagccgacg
    11761 ccgtcggcag acgtcgtgcg gacgacgccg accacagcga tctactggct ttcctgcagg
    11821 aggccgtcga ctccacggaa cacccgggca gcagcgatcg gctgacggat atcgaattgg
    11881 tcgaccagat caccaccttc ttcggcgccg ggacggagac gaccgcgagc acagtggcct
    11941 gggctctgca cctgcttgcc cgccaccccg aaattcagga ccggcttcat caggaaatcc
    12001 aagacgtcct ggccggtgaa ccgatgactt tcgagcggct gaccgatatg gaaatggcaa
    12061 gtcatgtcat caacgaaact ctccggcttt atccaccggc ctggctgctc acccgcacgg
    12121 tcacgaagga gactttgctg ggcggcttcc agcttccggc cgggaccacg ctggcctaca
    12181 gtccctacgt cattcaccgt cgaccggatt tgtacgacga tcccgatcgt ttcgacccgc
    12241 agcgctggcg gcacaccaag cctgatcgaa cggccttcat tccattcgct gccggagccc
    12301 gcaaatgtat cggcgatcgc gttgccgtca cccaggcgac gatggcattg atcactattg
    12361 tcggccagtg gcgcctgacg ccgctttcgg atcaagctct cgagcctgct gtcaaggcga
    12421 ccttgacccc ccgccacctc cgcctccggg ttactgcgcg ccgatccctg taaccatccg
    12481 agccgcccga atagattgga gaaccacaat gtcggtggac gcaggacaag cagtcgaggg
    12541 tctgcgcatt cccttcccca gcgcccgcaa cccgcgaaca gagctggtcc gtaagccgca
    12601 tcgggattgg atcgacacca tggggatcgc ccctgcggcg accgcggaca tcggtgccga
    12661 cctgccgctc atcatcggcc gtctctatcc acacgccggt gtagacgatc tggccctggt
    12721 caccgactgg aattgctggg gctttctcta cgacgacgaa ttcaacggcc gtctgggcac
    12781 cttgcctggg gcggtggcag cctcagtcga aggcatgatc gagatcatct gcgcaccagc
    12841 tactttccaa gaagcttccg aggtgccgtt gactcgggcg ctcgccgaca tgatgcgccg
    12901 attccggggc agcgcgtcgg cgatctggtt ccatcgattc agcgaacact tcgctgcggg
    12961 ccttaccggt ttcgcccatc acgccgccgc tcgcgcgacg ggcggatcaa ccagtatcga
    13021 ggactacctc gcccatcgac gactcgatat agtgtccgac ccgctgctgg atttcatcga
    13081 actgaccgac gactgcgaac tatcgccggt agtgcacacc agcccggaga tgcttcgcct
    13141 gcgccgcgca gcattggaca tcatcatcat gatcaacgac gtcttctcct acgaaaagga
    13201 actccgctgc ggcgacacgg agaatgcggt agccgtcctg gaacgatcga ccgggctcac
    13261 ccacgaagac gcgacagccc gcgcgatcga gatcgcaaac caaaatatcc tcgtcctagt
    13321 cgaagccaca gagaccctgc cggccgcatt gcgcaaactc gacgccgacc tcgaccagat
    13381 cgaccgagcc ctgcggttcc tcaccggaat tcagaccgtg gtgaaggcga catacgacat
    13441 ccacctcgaa agcgcccgat acaccgccgg atagccccgc tctgtatgta ccgaacaatc
    13501 gttcggtgaa tttctgtagg aggactgcga tgtcggaagt tcggtccgaa gcacgccagt
    13561 acccgatggc ccgcgggcgc tgcccgttcg acccgccacc cgagctcggc cgcaggcagc
    13621 gggaggagcc ggtgtccaag gtgcggatct gggacgacgg cgagccgtgg ctgttcaccc
    13681 ggtacgcgga cattcgcgcg ctgctggccg atccgcgcgt cagcgccgat tcggcccggg
    13741 acgggtaccc ggcgcagtcg ccggggatca aggccggtcc cgagcgggcg aaattgttca
    13801 tcaccatgga caacccggaa catgccgcgc agcgcagcct gctcaccgcc gacttcaccg
    13861 tgcggaagat agaacggttg cggccgcgga tccagcagat cgtcgatgac ttgatcgacg
    13921 atctgctcgc tggcccgaaa ccggccgacc tggtggaggc gttcgcactt ccggtgccct
    13981 cgctggtgat ctgtgaactg ctcggcgtgc cgtatgccga ccgggccttc ttccaccggg
    14041 tgagcaaggt gctgaccgcg aggtatacgc ccgtggccga atcactcgcc acgatggaga
    14101 cactgctcga ctacctcggc ggactggtac gggacaagct cgccgacccc ggcgacgacc
    14161 tgctgagtcg gcttgcgaca gaacacatct ccgccggcgc ggtgacggtc gcggaggcgg
    14221 cgtcgatggg gctgctgctg ctggtagccg gacacgagac gacggccaac atgatcgccc
    14281 tcggcaccgc cgcgctgctg gagcatccgg atcagctcgc cgccgtccgc gacggtgacg
    14341 acgcgctggt ggcgaacgcg gtcgaggagc tgctgcgcta cctcaccatc tcgcacagcg
    14401 gacgacggcg cgtggcactg gaggatatgg aggtcggcgg gcagcggatc cgccagggcg
    14461 acgggctgat caccgcggac agcgtggcca accgcgatcc ggcgcggttc cccgaccccg
    14521 accggctcga cgtgacccgc gaggcgcgcc accacctcgc gttcggctac ggcatccacc
    14581 agtgcctcgg ccaggcgctc gcgcgggtcg aactgcaggt ggcctaccgc acgctctacc
    14641 ggcggatccc gacgctacgg ctcgcggtcg cgctggacga ggtcgagttc aaagacgaca
    14701 tggtcgtgta cggggtgcac gaactcccgg tgacgtggtg aacccggggc gtcgataccc
    14761 cgccgggtga gccgaccggc gatcgacctc cacagaaaga gcgcgagata gatcagcacc
    14821 gcgccgtact cgttgcgaac ctgggttgat gaatgctctg gcgattgggt gcttgcgcgg
    14881 ggaggagttg tcgcgcgcgc tggctcgggg actgttcgat gcctacggca gcagaacttc
    14941 gcggcgaatg acacccgacc ggctccgcat gggcatcgaa tcgctaccca tgcgggaagt
    15001 ctgctggaca gagttcctga gtgtttgagc gttgcgcaga gcgggtatcc ccgctctgac
    15061 ccggagtatt tccaggtcag agcgggtgtg gcgcccccgg caggaatcga acctgcgacc
    15121 tagggattag aaggcccttg ctctatccaa ctgagctacg gaggcagtgg gttccaccat
    15181 ggccgacatt ggtcgtgctg tccagcgcgc caattatagc gaccgaccag atggctaagg
    15241 gtccagcgcg acggcgagta cgagcatcgc ggccaagatc acctctagca ccaggtagaa
    15301 ccaaacgggg tagaaggcgg acgggctttc gacgacggac gaccacactc ggccgaacgc
    15361 catcccgccg agcgcggcgg ccaccgccac gcacgcaccg aatctgaggt caccgacatc
    15421 tgcggcggcc aacccgagga tcaccgcgat ggcgatgccg aagccgccgt agacggcccg
    15481 cacctcggcg cgggcgtccg cgcggtcggc gagcagcccg agcgggtcga ccagttggct
    15541 gggccgtaag agcccgaaaa cgcccatggc agcgaagaac aacgccacca aggcaatcaa
    15601 cacgatcgat acgaccgaca caacacctcc gtgatccgca gcccacaata tcggcccaaa
    15661 cccggcgcgg ccacgcgata acactggaac tacgctcagt cgtatgtcgt ctgcgctgga
    15721 cccgtccgct tcccccgatc tggaaagcaa ccggccggcg gcgacatacg cagtggtgat
    15781 cgcgctttcc gcggcgatcg ccgcgatggt cgcggcactc gtggtgggtc tgtccgcggc
    15841 gcaggcgctg agtttgctcg gcattccgga tcccggcgcg ttgaccacct acgggctgcc
    15901 cgcggtgcgc gcgctcgcgg atctgtccgc ggcgttgacc gtcggctcgc tgctgttcgc
    15961 cgccttcatg gtgccgccgc aggcgagcgg gttgctggac gtcggcggct atcgcgcgat
    16021 gcggcgcgcc tcgaacttcg cgctgctctg ggcttgctgt gcggcgctgc tgattccgct
    16081 gaccgtgtcc gacaccacag gacaaccggt gcgcgacacg ctggacccgg tgggtctgtg
    16141 gcgggcgatc gatcagatcg agctggcggg cgcgtggcgc acgacggtgc tgttcgcgtt
    16201 gatcgtcgcg gtcggtgcgc ggctcgcatt gcgctggggg tggacgccgg tgctgttcgg
    16261 cgcggcgatc gccacgatga tgccgctcgc gctgaccggt cattcgtcct cgggcggcgc
    16321 gcacgacgta gccaccaaca gcctgatcct gcatctggtt tcggccgcgg tgtgggtcgg
    16381 cggactgttc gcgctgctgg cgcatgcccg tcggggcggc gcgcacacgg atctggccgc
    16441 gcgccgcttt tcgctgaccg ccaccttcgc gttcgtcacg atcggggtga gcggggtgat
    16501 caactcgtgg gtccgggtgc cctgggacga gctgttcacc agtacttacg gcaggttggt
    16561 gctggcgaag gcggcggcgc tggtgctgct cggcctgttc ggttacgcgc aacgccgcgc
    16621 cgcgctgccc gcgctggccg cggacccgaa agaccgcggc gcactgatcc ggttcgccgg
    16681 agtcgaggtg ctggtgttcg ccgcgacgat gggtctcgcg gtgggcctcg gccggacgcc
    16741 gccgcccccg cccaccagca tccccacgcc tgcggaggtg gagctgggct acaacctggc
    16801 cgggccgccg acggtcgcgc gcatgctgtt cgactggcgc ttcgacctga tcttcggcac
    16861 gttggcgatc gtcctcgcga tcggatatct gctcggcgta cgcaggctgc gggcccgcgg
    16921 cgacgcctgg ccgatcgggc ggaccatcgc ctggctgtcc ggttgtgtgg tgttgctgct
    16981 ggccacctcg tccggggtgg gtcggtacgc gccggcgatg ttcagcgtgc acatgggcgc
    17041 gcatatggca ctgtctatgc tggcgccgat cctgttcgcg ctcggcggcg tggtgacact
    17101 ggcgttgcgc gccttgccgc ccgcggggcg cggtggggca ccgggaccgc gcgagtggat
    17161 cctggccgcg gtgcacaacc cggtgtcgcg gttcctgacc caccccatcg tggcttcggt
    17221 gatcttcgtc ggcgggttct atgcgctgta cctcggcggg atcttcgaca cctttgcgga
    17281 ttcccatggg gcgcatctgc tgatgaacct gcacttcctg ctcagcggct acctgttcta
    17341 ctgggtggtg atcggtatcg acccgaagcc tcggcaggtg gagccgctga ccaagctggc
    17401 catggtgttc ggctcgctgc cgttccacgc cttcttcggg atcgcgctga tgagcatgac
    17461 cacggtgctc ggcggctggt tctaccgcgg cctcggactc ggctggaacg gtgacctgct
    17521 cggcgatcaa cgcaccggcg gcagcctggc gtgggcgagt ggcgaggtgc cgctggtggt
    17581 ggtgatgctc gcgctgctca tccaatggtc gcgcagcgac aagcgattgg cgcaacgcac
    17641 cgatcgagcc gccgaccgcg accacgacgc ggacctcgcc gcgcacaacg cgatgttcgc
    17701 cgaactggcc aaacgtgatc ggggaacaca gaagtcggcg ggcgatccgg cacaaccgtg
    17761 atttgagtgg cacagtgtgt tccactgaca ctgtgtcctg cgaaggcaat cgtgcgaaat
    17821 ccgtcttgcg ggacggtgct ccacgatcgg acactgtgct tcggacatgg ttgggcagtc
    17881 gtggtcgagt cgaatgtggt caaggtgtgg ttgtgaacga gcgttccatg gtcttccccg
    17941 agcacgacca catcgaccgt gtgcaccgat ccgatgtgcg ggccgcgcgc aagcggctgg
    18001 ccggacgcac ccgtaagacc ccggtcttcc acacctccgt cgccgggccg gacggcccgg
    18061 tgccggtcac gatgaagctc gaatacctcc agtacggagg cactttcaag gttcgcggca
    18121 gcctcaacgc gttgctggcg gcaccggact gcgccgagca ggtggtgatc gcctcgggcg
    18181 ggaacgcggg catcgccgcc gccttggccg ccgcgcagct cggaaagtct tgcaccgtcg
    18241 tcgttcccga gtcggcgccg cacaccaagg tcgccgcgat gtggtcgcac ggcgccgaag
    18301 tgctctggca tggcacgact tacaccgagg cgctcgacta cgccaccgaa ctggcggtgg
    18361 aacgcaaggc attgcgtctg catgcttacg acctggccgc ggtcgtcgcc ggagccggcg
    18421 tggtcgggtt ggaactcgag gagcaggtgc gcggacggcc gccggtgctg gccgcggtcg
    18481 gcggcggcgg actgatcgcg ggcatcgcgg ccgcgatcgg ccggcgccag cagatcatcg
    18541 gcgtcgaacc ggaaggcatt cccaccttgc atgccgcgct ggcggcgaac cggccggtcg
    18601 agatagcggt gtccagtatc gtggcggaat cgttgggcgc caccaggatc ggcgatatcg
    18661 cgatggacgt ggcgcgccgg cacgagatcc gttcgctgct ggtcaccgac gacgcgatca
    18721 ccaccgcgcg ggactatctg tggcgtgagt tccggatcgt ggtcgaactg gctggcgcgg
    18781 ttgcgctggc ggccgtacag agcggggtgt acgttccggc tcctggggag cggcccgtta
    18841 tcgtgctgtg cggggcgaat acggatctcg cggcgctcta gggacgaacg cggggtcggg
    18901 cgcggacgcg ggacttgccg ccgctgcgga atcgggcgcg gctgcgggtc ggtcgcgagc
    18961 gtgagattgg gcgcggtcgc agggctgtgc gtgagcgggg gattgggcgc gaacgcggga
    19021 tcggcggtcg ctgcgggatt gggcgtggtc gcggggttgg gcgtgagcgc gggactgggc
    19081 gcgcgcggga tcggcggtcg ctgcgagatc ggccgcggag cgcgaaatcg cctgcgaagc
    19141 accggatatc cacatccggg aaagttgtgc acattctcgg ctcgcaccat ccgatcggca
    19201 tccggatcgg cgacgctggt ggcaccccat tcaaggggcg gaagttcccg ggcaagcggg
    19261 cggaatgcga aggggcgtca ccatgtacga ggcgaatacg accgtgatcg gcacgatcgt
    19321 gaacaatccg gtgaagcggg atctgccgaa cggcgagcag atgctgacct tccggatggc
    19381 gagcaattcg cgcagactcg accacgcgac aggggagtgg gtggacaacg gcgctttgtt
    19441 cctcaccgtc tcctgttggc gccgtttggt atcgggcgtc gacgtatcgc tgcaccgcgg
    19501 cgaccccgtc ctggcccacg gccaactgcg ctcgcgcgaa taccgcggca gagacggcgt
    19561 agagcgccgc gacctggaaa tgcgcgccac cgcagtaggc cccgacctcg cccgctgcac
    19621 cgcccaggta acccgctggt ccgcagaccg ctggaccgac gaccaacccc cacaagaatt
    19681 ctcggtcacc gaatccggcg tcctgtcggg cgcactcccg cccacccaac cgccacaact
    19741 cgtcaccgcc gacgaagctg tgcccacccc ggtctgaccg cccggcgatt ccgccccgct
    19801 ccggtggtgt gaagaccaag cccggagcgg ggctccaacc gtcctgcgac cggggcgcga
    19861 tgagtgccag tggggtggaa tcttggtgat caggtcgcca acctcgtcat ccgagtagat
    19921 acgcgacgac gttccgttag cgccgaagca taggatgcac tcgtggatct ggcctacatc
    19981 ccggcgtctg gcttcatgag ctgcggcggt ggcgcaccgc tgcgcgagca tcccagggat
    20041 tggctggctt ggcacttcac ccatgctggc aacttgggcc gaatcgcgtc tgagaaggct
    20101 cttctcccag cctcagccgt aacgccgaaa gttaacgtgg cgaaccctgg cgtcaagcag
    20161 cggcgtgccc agatagttgt gaggcccgac agtgagtacc ctgcatgcta tgtgaatgag
    20221 catgtcccgt tctatatcgc ggccaagtcc cccatgctct acgtagttaa ccgtgggcac
    20281 gcggactaca gcggtggcag tgacgatttg gtgttgctcg gtttcgtatt aggcaatctg
    20341 gcagtttcgg gaagtctctg gtgtgctacg gaccagaacg ctgcgacgtc gacagtaggc
    20401 ttcagtcgca agctggatga tctcggtcac tttgtagact tcgacctcct gtgccagaga
    20461 gactggtaca acacacccga cgatcaaaac cggatgagtc gtcgagctgc ggaggtgctg
    20521 gtgaaggacc gattcgacct gcgattggtc caggtggtga tagcgaagaa ggcttcggcc
    20581 ctggaagttg ccaaggtagc gttccaagat gtcggtggcg tacgcgagta tcacgtagta
    20641 ccggaaatgt tctactgaag gaggagtccg catggtcgtt gagcaggcga gcggcgatct
    20701 ccttgccgcc gacgccgaag cgctagtcaa tacggtcaac tgcgtgggcg tcatgggaaa
    20761 agggatcgct ctacagttta aaaggcggtt tccaagcgta ttcaaggagt acgaggctgc
    20821 gtgccgaaga ggcgacgtgc agattggaag aatgttcgtc agccctatcg aacaactcga
    20881 tggtgcgcga tgggtgatca acttcccgac aaaacgtcac tggcgttcgc cgtcgaagct
    20941 cgaatacatt gaatccggtc ttgatgatct aaagcgcgtg ctgatcgaat atgagataaa
    21001 ttccgtcgcc ataccaccgc ttggggctgg gaacggtgga ttgtcgtggg cggacgtcga
    21061 accattaatt cgacgtaagt tgagcggaat ggaaggtatc cgggttctcc tcttctcgcc
    21121 ctcctcggtt cagcgaccag ttgctgcgcc agagcatatt aatatgactt ggggtcgtgc
    21181 gctcgtggta tcgctgattg gatcctacgt cgctcaacgc gcgatagccg agccatggga
    21241 agatcagcat ggtgcctccc atcttgagat acagaaactt atgtatttcg ccgagttgct
    21301 tgagccgcgc ctgaaattgg acttcagtca aggccgctac gggccttata gtgagcgtgt
    21361 tcggcacctc ctgcagggaa tggagggtgc atacgtcacg ggcctcggcg acggtgcttg
    21421 cagggtgctt gatctaagtc cgatagctcc gactgaacga ggctattcgg aggccaagat
    21481 gttccttgcc aatggtgact atgatcaggt ctattctgta atcgaccgtg tgatgtcgtg
    21541 gattgaaggg ttcgaagggc cctacggtgt ggaattgctc gcgagtgcgg attgggtcgc
    21601 gcggcatcat cgcgcctcag atgcgactaa agctgctgaa gtggtcagga aatggaccga
    21661 gcgcaaaggg cgcctattca cggatgagca tgtcgcatca gcgttggggc atcttaaagc
    21721 tgtgggggca ctgcagggtt gacacttggt attgacgact tggtgacgcg aggaactggt
    21781 ggcactgacg gacgatgtgc aagagttgtg gtttgaatct cacgaggaca tcgagcgatc
    21841 aggcactgta ccgaagctgg taaggatgga tcagccgtac ttggaaatgg cactcggttt
    21901 ccgtgcgcga caggactgga aatcggtggt gtcacggggg tgtactcgac ttcgcgtgcc
    21961 gtctggcgct taggctgctg gctttcgcgc ggtggcggcg gacgtttgag cggtgttcat
    22021 taagcctgcg tctacgctct catgtaacga tcttgcgggc caggcacgac taggcgtcgg
    22081 ggtacctcga ctactcaccc ccgtgcccac cctcggtggg aacgcgcggc gactccgccc
    22141 ccgtccttgg catcacgacc gcagctggag cgggggtgaa ctggtcgacc gtgggggtgg
    22201 gcgggatccc ggtgggggtg ggaatcctgg tgatctggtg ctggttgaat gtacgggccc
    22261 gtgagctgcg agggtggggc agtggggcgt aatcgttgat ccccttaccg ataggcttcc
    22321 ctgtatggct gagttcattt acacgatgaa gaaggttcgc aaggcgcacg gcgacaaagt
    22381 cgtgctcgac gatgtcacct tgaacttcct tcccggcgcc aagatcggtg tcgtcggccc
    22441 gaacggtgct ggtaaatcca gtgtcctgaa gatcatggcc ggactggacc agccgaacaa
    22501 cggcgacgcg ttcctggcga ccgacgcgac cgtcggcatc ctgatgcagg agccggcgct
    22561 caacgaggag aagacggtcc gcggcaatgt cgaggagggc ctcggcgagg tcaaggtgaa
    22621 gctggatcgc ttcaacgaga tcgccgagct gatggcgacc gactactccg acgagctcat
    22681 ggacgagatg ggcaagctgc aggagtacct ggatcacgcc gacgcctggg acgtcgactc
    22741 ccagctggag caggccatgg acgcgctgcg ctgcccgccg ccggacgagc cggtcaccaa
    22801 cctctccggt ggtgagcgcc gccgcgtcgc gctgtgcaag ctgctgctga gcaagcccga
    22861 cctgctgctg ctcgacgagc cgaccaacca cctcgacgcg gagagcgtgc tctggctcga
    22921 acagcacctg gccgcgtacg cgggtgccgt cctcgccgtc acgcacgacc ggtacttcct
    22981 cgacaacgtg gcccagtgga ttctcgaact ggaccgcggc cgcgcctacc cgtacgaggg
    23041 caactactcc acctacctgg agaagaaggc ccagcgactc gaggtgcagg gcaagaagga
    23101 ccagaagctg cagaagcggc tcaaggacga actggcctgg gtgcgctcgg gcgccaaggc
    23161 gcggcaggcg aagaacaagg cgcgcctcgg ccgctacgag gagatggcgg cggaggccga
    23221 caagcacagg aagttggatt tcgaggagat ccagattccg gcgggcccgc gcttgggcaa
    23281 cgtggtggtc gaggtcgagc acctggacaa gggcttcggc gaccggcagc tgatcaagga
    23341 tctgtcgttc acgttgccgc gcaacggcat tgtcggcgtc atcggcccga acggtgtcgg
    23401 taagacgacg ctgttcaaga ccatcgtcgg cttggaggcg ccggacagtg gcacggtgaa
    23461 gatcggcgag acgg
//
