LOCUS       NC_017542              23231 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Paenibacillus polymyxa M1, complete sequence.
ACCESSION   NC_017542
VERSION     NC_017542.1
KEYWORDS    RefSeq; complete genome; complete replicon.
SOURCE      Paenibacillus polymyxa M1
  ORGANISM  Paenibacillus polymyxa M1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Niu,B., Rueckert,C., Blom,J., Wang,Q. and Borriss,R.
  TITLE     The genome of the plant growth-promoting rhizobacterium
            Paenibacillus polymyxa M-1 contains nine sites dedicated to
            nonribosomal synthesis of lipopeptides and polyketides
  JOURNAL   J Bacteriol 193 (20), 5862-5863 (2011)
   PUBMED   21952539
REFERENCE   2  (bases 1 to 5864546)
  AUTHORS   Blom,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2011) Cebitec, Bielefeld University,
            Universitaetsstr. 25, D-33615, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 01:49:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,687
            CDSs (total)                      :: 5,531
            Genes (coding)                    :: 5,427
            CDSs (with protein)               :: 5,427
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 45 of 104
            Pseudo Genes (incomplete)         :: 71 of 104
            Pseudo Genes (internal stop)      :: 16 of 104
            Pseudo Genes (multiple problems)  :: 23 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:14:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4907272
            Orig. end                         :: 4930503
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE577054.1.
            Accession number for plasmid pPPM1a in this genome project:
            HE577055.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23231
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="17"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23231
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23231
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13231](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13231
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(95..111)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    975..986
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 20.11"
                     /tool="antismash"
     gene            complement(1044..2171)
                     /locus_tag="PPM_RS22245"
                     /old_locus_tag="PPM_4263"
     CDS             complement(1044..2171)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344663.1"
                     /locus_tag="PPM_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4263"
                     /product="transglutaminase domain-containing protein"
                     /protein_id="WP_013373078.1"
                     /transl_table=11
                     /translation="MNRKIGVRLVKCLVAGAALAVLLPQAVEWGNNVYAASVKPTPSVS
                     SQQLQNKLLQAMATRSETLTFTYQGRVNGLKQQLQTAIQQAMESDPYVNYTIKSYAFSY
                     TGTTTSAQVTIRLSYRETKEQTAYVDSTVQAVLGDIITKGMTDHEKVKAIHDWIVVRLK
                     YDEAQQKYTAYDGLKTGSTVCQGYSLLAYKMLERAGITNRIVEGRAGGQLHAWNLVLLD
                     GRWYHMDTTWDDPTPDRANEVSTSYYLLTDSEMRRDHSWVKQYPQANTSYRETLSALIA
                     AGGAKAAVYQKLYNNLEYPLQDGKGLVKSSADIKEQVRKMITKGETSITFGYQGTERSL
                     KEDLQSLYQLGLKSISYQITDLGSTGNLRVTLKWT"
     misc_feature    2410..2425
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.16"
                     /tool="antismash"
     misc_feature    complement(2413..2428)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 26.82"
                     /tool="antismash"
     gene            2452..2697
                     /locus_tag="PPM_RS28825"
     CDS             2452..2697
                     /GO_function="GO:0046914 - transition metal ion binding
                     [Evidence IEA]"
                     /GO_process="GO:0006811 - monoatomic ion transport
                     [Evidence IEA]"
                     /GO_process="GO:0055072 - obsolete iron ion homeostasis
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015956.4"
                     /locus_tag="PPM_RS28825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FeoA family protein"
                     /protein_id="WP_080567882.1"
                     /transl_table=11
                     /translation="MAECISLLRTPLGQTVRLQSLAPLHPSLRRRLTDMGINEGSIIRL
                     KKISLLGGPIVIECNGQLVGLRQNQVKQLEVVPTWT"
     gene            2688..4697
                     /gene="feoB"
                     /locus_tag="PPM_RS22250"
                     /old_locus_tag="PPM_4264"
     CDS             2688..4697
                     /GO_function="GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="feoB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311964.1"
                     /locus_tag="PPM_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4264"
                     /product="ferrous iron transport protein B"
                     /protein_id="WP_013373080.1"
                     /transl_table=11
                     /translation="MDMIALFGNPNTGKTSLFNKLTRTYAEVGNWSGVTVEKKTGILRD
                     KSAVLVDLPGAYSLLPLSLDEGVATRYLLEEPPAALINIVDASQLQRNLYLTVQLLEYG
                     RPLVLGLNMTDVADATGLRVNKELLADQLNVPIIPMVARTGSGSKQMLASLREVRHTSN
                     AFQLDYGPAVEAAIADICSLLPHTSVPQLRWAALQCLENNPVVMEWMTNETLREQVTAR
                     IQRCEEELLREGYASTPAQHIRFVRTAWIAELCTKAVDTSKLRPHSLTDKLDALLTHRY
                     LGIPIFLLLMYATFKFTFDWAGTILSDMLDEFFSGTLSSWITELLVQLNASAFTQSLVV
                     DGIVAGVGGVLVFLPQIAILFLIISVIEDSGYMARVTILMDRLMQAVGLNGKSFIPFII
                     GFGCNVPAIMAARTIEQPRERLITTLLVPFMSCSARLPVYALFAGVFFPSHAASIIMLM
                     YVLGIIVSLILAKIFSKVSILSGEPSLFIVELPPYRVPQALTLFRSTWEKVKGFVRKAG
                     TIILAGSVGIWLLSNFGPQGFGVEMDDSLLATVGGWFAPLLAPLGFGTWQAGASLLTGF
                     MAKEVVVSTMNIIYHVPDMQGLELQVRQAFTPLASFSFMVFILLYVPCLATVAVIRKET
                     LSWRWTAFSVIYPLTVAYIIAVLIYQCGRLLGWG"
     gene            4734..4916
                     /locus_tag="PPM_RS22255"
     CDS             4734..4916
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425972.1"
                     /locus_tag="PPM_RS22255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_013373081.1"
                     /transl_table=11
                     /translation="MVNIIILLVILGYSAWVLVRFLRKSRQGACAGCSSSKSCPGCAVS
                     SVNEDTRKTTAAHKG"
     CDS_motif       4734..4820
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVNIIILLVILGYSAWVLVRFLRKSRQGA"
                     /locus_tag="PPM_RS22255_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4821..4916
                     /prepeptide="core"
                     /locus_tag="PPM_RS22255_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="2881.2"
                     /monoisotopic_mass="2879.3"
                     /core_sequence="CAGCSSSKSCPGCAVSSVNEDTRKTTAAHKG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVNIIILLVILGYSAWVLVRFLRKSRQGA"
                     /leader_location="[4733:4820](+)"
                     /alternative_weights="2899.2"
                     /alternative_weights="2917.2"
                     /alternative_weights="2935.2"
                     /alternative_weights="2953.3"
                     /alternative_weights="2971.3"
     gene            complement(5058..5774)
                     /locus_tag="PPM_RS22260"
                     /old_locus_tag="PPM_4265"
     CDS             complement(5058..5774)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373082.1"
                     /locus_tag="PPM_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4265"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013373082.1"
                     /transl_table=11
                     /translation="MTQEHKSSFLQLDQVSFSYGSREIIHGLNWDVPDHQITVLLGPNG
                     AGKSTLLSLIAGLHQVQKGTIRFNQTIIDFENQNYKSMVGYLQEFPFYYPALSVSEMMR
                     LIGGLRQVPKDQLEMRIAKWLDRFKLEDYQNIKMEELSQGTKKRVALASMLLHEPRILI
                     LDEPTNGLDPDQVMIVRSILREYLTEGRVILLSTHIIGLAEKLADQVAILRNGRITYSG
                     RSTIDLERLYIAHQHD"
     gene            complement(5788..7041)
                     /locus_tag="PPM_RS22265"
                     /old_locus_tag="PPM_4266"
     CDS             complement(5788..7041)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="PPM_RS22265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PPM_4266"
                     /product="hypothetical protein"
                     /protein_id="WP_013373083.1"
                     /transl_table=11
                     /translation="MTSIKLCEILYLKQLRKLTKMEAALFIFLLILIPNGLANATLRLN
                     SLGIKAMMWAIIYGIIGFLIQFGISISISKVEEVRFLWSIGKGNWFLTQYTIVKKIPFL
                     ILLLWIVVGQILWDVHHNYIFSMVSGLILGVLLAEIFWYITLFRKFSGYAISFFFLSLV
                     VVYFILPMSLSVRILTWILLCISMGYITLYFAQRSWSVFLQYHGSKKVLGRRGWLSQCP
                     LLKKELLFIIRPVNLFSFFILALGIEVLNSYIIRESPFILSISSAILSWFAVDIWAVKS
                     LVIEEKGLLIYKATLFAWKKMLRTKWLILCVLNIGIIFMHQWFWGIYLQISPVILSIQT
                     IWSIFLSTTLISLGMPLGYKFLSIDYLGNYRIKFLGSWVIAMSMLLLLYLHQFHKVLFV
                     AISVMIYTRFILFYKKVS"
     gene            complement(7058..9220)
                     /locus_tag="PPM_RS22270"
                     /old_locus_tag="PPM_4267"
     CDS             complement(7058..9220)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="PPM_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4267"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_321167108.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.5e-37, bitscore:
                     124.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLNFNKKVPFIEQMEHSECGLASLAMILGFYGHNISLTELRNQV
                     GAVRAGISMQQLQEIGSTYHLKSRGYRATASQLNELIAPLILLWDNQHFVVLEKIKKKK
                     VIILDPAFGRLILPLKEFTEKYSGFALSLIPLKDFRSKRKRPKWMFYIKLAFKSRKLLI
                     SVFLVSILLQGLGVLIPKITQFSVDNLLESKNNSFLVPLGWAIFTIFLFSQLFQFLRGY
                     MIAKLQSQMDTSMMTQFIAKLFKLPFEFFENRKGGELVFRANSNVTIRRVLSNRVITIF
                     IDGLLLITYAALMINLLWQIGLLVTIIGFLLLLITVLSSFTTHRLSRKETSSQAEMHGF
                     LSEHIHGITDIKVLGFESRVFKKWEELFKKQLTNTEKRVIWNASLDSMTVSIQFIFPLL
                     ILWIGFHYVLEGWITFGGLLGLQTLSTAFMVPLVSLGSTLSELVTVGTYIQRIQDVIEN
                     VEEPSGNHKPNHTFKGYIKFKDVSFNYHRFGKYVLKNINLEIFPGEKVAIVGASGSGKS
                     TLAKLILGLYKASIGEVSVDNIPLDQWHLREFRQKIGVILQETKLFNVSILDNIAMDNG
                     DCTIDMVVRAAKQADIHRFIMSLPLGYQTVVSENGLNFSGGQRQRILLARAFLAEPQIL
                     LLDEATSSLDSVSEQLITDFLQERHCTQIIIAHRLSTVQRADRIIVLDQGEIIEQGNHQ
                     ELIGLKGKYFDLYNLKKTDFQVEPVL"
     gene            complement(9204..9446)
                     /locus_tag="PPM_RS22275"
                     /old_locus_tag="PPM_4268"
     CDS             complement(9204..9446)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373085.1"
                     /locus_tag="PPM_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4268"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_013373085.1"
                     /transl_table=11
                     /translation="MRENHNLSPKEQKVAICIAQGYKDSEISQNLSISMRRTAEIVASI
                     KEKWNIKTRVEIGIFAYHYGLVFLTEGIEVHSSEF"
     misc_feature    complement(9612..9627)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.44"
                     /tool="antismash"
     gene            9672..9893
                     /locus_tag="PPM_RS22280"
                     /old_locus_tag="PPM_4269"
     CDS             9672..9893
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373086.1"
                     /locus_tag="PPM_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4269"
                     /product="mersacidin family lantibiotic"
                     /protein_id="WP_013373086.1"
                     /transl_table=11
                     /translation="MTKEEMIQAWKNPKLRVAGEGIEHPAGDALVELSADELSRVHGGL
                     GVQPDSTPTITVTVIGVTVLVCFPGHAG"
     CDS_motif       9672..9803
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MTKEEMIQAWKNPKLRVAGEGIEHPAGDALVELSADELSRVHGG"
                     /locus_tag="PPM_RS22280_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9804..9893
                     /prepeptide="core"
                     /locus_tag="PPM_RS22280_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="1.90"
                     /molecular_weight="2771.2"
                     /monoisotopic_mass="2769.5"
                     /core_sequence="LGVQPDSTPTITVTVIGVTVLVCFPGHAG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTKEEMIQAWKNPKLRVAGEGIEHPAGDALVELSADELSRV
                     HGG"
                     /leader_location="[9671:9803](+)"
                     /alternative_weights="2789.2"
                     /alternative_weights="2807.2"
                     /alternative_weights="2825.3"
                     /alternative_weights="2843.3"
                     /alternative_weights="2861.3"
     gene            10001..13231
                     /locus_tag="PPM_RS22285"
                     /old_locus_tag="PPM_4270"
     CDS             10001..13231
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373087.1"
                     /locus_tag="PPM_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4270"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_013373087.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-94, bitscore: 316.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.1e-61, bitscore:
                     205.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQIMRALFLQERKNLFDQAFQDFNYKNWKQDKEKTTELIDEWF
                     KFALISTESKKEARFKALSMNEEIFGALIQSTENLKWDENYLTVIKEYQADWFQVLEEA
                     LKMNENQPVLQNESRTMDILVRPFIIWSRNQLKQHLCNIDNTQDFILHESTINSVLHTL
                     SFQLTQIAGRSFVLELNIAKALGELEGLTPEERFISFIEKKFVGHKQLVSFFSEYAVIA
                     RTLAERTMLFVNVTKETLDRYLLNRSMIIDTFSLHSSELIRIDAGFGDSHQQGRTVMRL
                     YLANGQSFMYKPKPLDISLHFQELIQWFNDKGFSPFLQRNSVIALDGYGYEKFIEAKPC
                     KTEEEIQCFYTRLGALLAIIYVLDGTDFHFENLIAFGEHPMLIDLETLFHNQVYHNVPD
                     SADIEAQFKICNSPLGTSLLPILFHQDDKGFGLELSGVNGERQMTPYPVLSLVDVNTDN
                     MRYIRKSQSTSTGNNRPSLEGEFKNAGDYTAEIVNGFQSLCSMLLQYKMDLLVPTSPLF
                     SFNNTPVRIVLRSTQFYTNFLLESRHPDYGRDALNQENLLDRIWFSWLDDRIISSELQD
                     LRAGDIPYFIGTPNSLDLWDSYGRCIKDVFTRTSMSIVEDRLRSLSTDSISLYSDWISS
                     SIAGSSLGKHVHKVHAPSQNEKVMTSDYSPKPLHSENFLETAKILGDELIEKSVFSQSK
                     RYVTWIGMNLNYRGQLYLSALSPGLYDGTAGIALFLAYLGKISKEEKYTNIALAALETT
                     LSKIPVHLKFPSAFYGQASLLYTLSHFESLLGFNDAWSKRKLDIISNLEDSIDEDTFFD
                     LLGGSAGVIHVLLNEYSLTKSVKTLEVATQYGEHLLKHGEKNNEMISWTSSVSPTPYVG
                     FGHGSTGIASALFRLAAVTKNNCYYATAEKAFAHLTESYSPNYFNWIDQDIKENHDLAN
                     WCHGASGIGIGLTLCMPYLNSSLIPDIVQNIEIAVNTTLKYGFNKSHCICHGSLGNIEL
                     LILAGQALNRPEWVAEAKKQGNIALSYFFEHSKFKTGLPTALDSQGLWLGLSGIGYQFM
                     RLHSLTSLPSILSLQEPLYKESSCTKRP"
     gene            complement(13304..14827)
                     /gene="xylB"
                     /locus_tag="PPM_RS22290"
                     /old_locus_tag="PPM_4271"
     CDS             complement(13304..14827)
                     /EC_number="2.7.1.17"
                     /GO_function="GO:0004856 - xylulokinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311965.1"
                     /locus_tag="PPM_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4271"
                     /product="xylulokinase"
                     /protein_id="WP_013373088.1"
                     /transl_table=11
                     /translation="MQEKLKQELERYVIGVDLGTSAVKTVLVNRKGQVAYETSQSYPLH
                     QPKAGYSEQQPEDWVRGTLASLKELVEKAGISGTDAVDGISFSGQMHGLVLTDKEGQVL
                     RPAILWNDTRTTAQCRRIEEQLGPALLSIARNRALEGFTLPKLLWVQEHEPDVLARAAH
                     FMLPKDYVRYCLTGGLAMEYSDAAGTLLLDIANKQWSEEIAAAFDLPLSLFPPLVESFD
                     QTGTLLPEIAEQSGLSSETKVYAGGADNACGAIGAGILSEGRTLCSIGTSGVVLSYEER
                     KDIDVQGRAHFFNHGEQDAYYIMGVTLAAGYSLTWFKDTFAPEHSFDALLEDVNSIEPG
                     SRGLLFTPYIVGERTPHPDAAIRGSFIGMDAGHKLPHFTRAVLEGITFSLKESIDILRG
                     TGKTVNEVISIGGGARNETWLQMQADIFNADIVKLESEQGPALGAAMLAAYGSGWFESL
                     QACAEAFLREAARYTPNPERVAQYEGLYELYREVYLHTRELSEQLAVYR"
     gene            complement(14884..16200)
                     /gene="xylA"
                     /locus_tag="PPM_RS22295"
                     /old_locus_tag="PPM_4272"
     CDS             complement(14884..16200)
                     /EC_number="5.3.1.5"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0009045 - xylose isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432158.1"
                     /locus_tag="PPM_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4272"
                     /product="xylose isomerase"
                     /protein_id="WP_013373089.1"
                     /transl_table=11
                     /translation="MAYFEQVSKINFEGKQSDNPFAFKFYNPQEIVAGKTMEEHLRFSM
                     AYWHTLVAGGSDPFGVETAERPWSKFTGLDLAKARVEAAFELLDKLNLPYFAFHDVDIA
                     PEGASLKEFYSNLDTIVDLIEEHMKATGKKLLWNTANMFSHPRYLHGAATTCNADVYAH
                     AAAQIKKGLEVGKRLGADNYVFWGGREGYETLLNTDLKLEQDNLGRMFHMAVDYAREIG
                     FDAQFLIEPKPKEPTKHQYDFDAATTIAFLQKYDLDQHFKLNLEANHATLAGHTFDHEV
                     RVARVNGMLGSLDANQGDLLLGWDTDEFPVDLYDATLTMYEVLQNEGLGRGGINFDAKV
                     RRASFEPEDLFLAHIAGMDTYAKGLKVAAKLIEDRVFEDFIEKRYSSFKEGIGADIVSG
                     KATLASLAEYALANEAPRKNVSGRQEYLKATLNQYILAD"
     misc_feature    complement(16220..16231)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.09"
                     /tool="antismash"
     gene            16335..17507
                     /locus_tag="PPM_RS22300"
                     /old_locus_tag="PPM_4273"
     CDS             16335..17507
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425974.1"
                     /locus_tag="PPM_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4273"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_013373090.1"
                     /transl_table=11
                     /translation="MNVTGDQALVKKLNKSIVLERIRLHAPLSRAQLSSQTGLNKATVS
                     NLVAELITDGLVYETGLGESSGGRKPLMLLFNSRAGFVLGIEVSVQYIKGALTDLAGTI
                     ETELTLSLTQHDPDFVIEQIRKLVQKLMQVTPPSPHGIVGIGLGVPGMVDETGNVLFAP
                     NLGWEEVPLRQQLETELGLPIVVDNEANVGAQGELYYGMDADHRQLVRDLVYISAGSGI
                     GAGIIIDGKPYQGAWGYAGESGHMSIDWNGRLCSCGSRGCWELYASEKAYVASTLKLPA
                     HNTAGLLPFAQQGDVSTLSVLGEIGRYLGVGITNIVNSLNPGMLIIGGPLAEARPWLEQ
                     SMREVIDERALPYHRRQLQIRFSTLGSRSTMLGAAYAATAPFLGRVRVSL"
     gene            complement(17592..17822)
                     /locus_tag="PPM_RS22305"
                     /old_locus_tag="PPM_4274"
     CDS             complement(17592..17822)
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344656.1"
                     /locus_tag="PPM_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4274"
                     /product="glutaredoxin family protein"
                     /protein_id="WP_013373091.1"
                     /transl_table=11
                     /translation="MEKAIVYTSTNCPHCRQVKSYLAEKGVEYEERNIETNEAFAQEVW
                     DMGIRAVPLTLIGEERISGMNKTKFEKVLNA"
     gene            complement(17881..18822)
                     /gene="trxB"
                     /locus_tag="PPM_RS22310"
                     /old_locus_tag="PPM_4275"
     CDS             complement(17881..18822)
                     /EC_number="1.8.1.9"
                     /GO_function="GO:0004791 - thioredoxin-disulfide reductase
                     (NADP) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820315.1"
                     /locus_tag="PPM_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4275"
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="WP_013373092.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.7e-50, bitscore:
                     168.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKSIIIGTGPAGLTAAIYLARANMNPLVIEGPQPGGQLTTTTEV
                     ENFPGFPEGIMGPDLMDNMRKQAERFGAEFRTGWVNKVDTTARPFTLDVEGLGELVTDT
                     LIISTGATAKYLGIPGEQDNIGRGVSTCATCDGFFFRGKEIVVIGGGDSALEEANFLTR
                     FASKVTLVHRREELRASKIMQDRARANSKIEWALNRTPVEVVADENGVTGLKVLNNATG
                     KEEIITVSGVFVAIGHHPNTGFLEGQITTDANGYIVVNPGTSETNVPGVFACGDVQDTR
                     YRQAITAAGSGCMAAMDSEKYIESLEHSALAL"
     gene            19104..19835
                     /locus_tag="PPM_RS22315"
                     /old_locus_tag="PPM_4276"
     CDS             19104..19835
                     /GO_function="GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013311970.1"
                     /locus_tag="PPM_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4276"
                     /product="ZIP family metal transporter"
                     /protein_id="WP_013373094.1"
                     /transl_table=11
                     /translation="MNDVFVGSLISALSTGLGAVPILFMRNITHRLRDVLLAYAAGIMT
                     SASVYNLIPEAIQHSNWFVLTAGILLGCLVLLVMEMYIPHADLEDPDSKTFQLESKSFL
                     IIAAITLHNLPEGLSVGVSYASETQNLGNLIAFSIGLQNAPEGFIVALFLVNQNIGRFK
                     ALGIATLTGAVEIITSLIGFYLSSWVNGLVPYGLAFAAGAMMFIVYKELIPESHGDGNQ
                     RIATFSFILGLITMIGLTEWL"
     gene            complement(19918..20379)
                     /locus_tag="PPM_RS22320"
                     /old_locus_tag="PPM_4277"
     CDS             complement(19918..20379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820316.1"
                     /locus_tag="PPM_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4277"
                     /product="hypothetical protein"
                     /protein_id="WP_013373095.1"
                     /transl_table=11
                     /translation="MTIAFIAVAVVALIFLLVFNTKMTRKSSAKNRPSQEESRQRSKRP
                     YPVQVEPKAHELTEHNGEMPPKDSEVEEHRAKEHQKLPDIQTDMKVEKDRKNIEGAYGD
                     QDYRAALRGFAGKDGEKDGGSPRSNGKKGTSKSKDEQYREALRSMNQKK"
     gene            complement(20390..20944)
                     /locus_tag="PPM_RS22325"
                     /old_locus_tag="PPM_4278"
     CDS             complement(20390..20944)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688620.1"
                     /locus_tag="PPM_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4278"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_013373096.1"
                     /transl_table=11
                     /translation="MTTRIMIVYDSENGHTERLARSIAEGARLNHTEVALKHVNEADVN
                     ELVSADAIIWGCPGHFGTISSGLKSWIDKLGYLWAQGKLVDKIGAVFCTTATVHGGLES
                     TLLNLITPMLHQGMIIVGLPASITENALYGSYYGVGVTCPVETDPDGPPNLPTGDDLAL
                     GRSLGKRVAEMAGRYRSAERE"
     gene            21079..21714
                     /locus_tag="PPM_RS22330"
                     /old_locus_tag="PPM_4279"
     CDS             21079..21714
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1029: RND family
                     efflux transporter MFP subunit"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820318.1"
                     /locus_tag="PPM_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_4279"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_013373097.1"
                     /transl_table=11
                     /translation="MNSRAILVNLLVIIIILAGGGAAAYYYNQSANYIKTDNAQVSGQA
                     VTVASPSGGKLTGWNAEVGKTYTAGSSLGSVEGGGSRISVTIPTDGTIVQQTAVNNSVV
                     GAGTPLAKAFDLNNLWITANIDETAVQDLQVGQTVDVYIDAYPDTSLTGKLEKIGLATA
                     STFSLLPTSNTTANYTKVTQVVPVNISIQGYKGLGIIPGMSATIRVHK"
     misc_feature    22702..22717
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
ORIGIN
        1 gcagtctgcg ctgcaaatgc ttgacacagg caaggactat gatgccacca ccaatcgcac
       61 ctgcaaaata cgccgcatta atgtatcccc accatgcctc gctcttgtgc aagacctgct
      121 gagcgaaggc aagcgtgaac gcgcctaccc aaactgatcc ccccagcagg tcaatcatat
      181 ccataaaaat aagagccttc agtctgtgac tggctccgat gagactccag ccttcacgca
      241 gtatttcttt tttacgttta ggaggcaccg ctgtgctctc tgattccgga ccatacagct
      301 tatcttccaa ctgcgctgga ggcaagtcat gttgcccttg tcccggctcg gttacaacct
      361 cagaagccaa gacatcccca ttttgtaccc ttgttccagg ctgaagcaaa taatgagctt
      421 tgccctctag gggatctcga atcaagctgg tgaagatcag cgctatcaaa tacagaccgc
      481 cagccaccag caatgttttc tccgagccca gcatagctac gagcacacca ctaagccccc
      541 accctgctaa ttgcaccgtc tgatcactga ccgataccag actgtttgcc cgcatgagtc
      601 cttccccaga agcaaggcgg ggaatcagtg cattgcgcgc aggggtggtc cagccgtcca
      661 gaaaggacat ggcagtcacc agcgcaaaca caattaccca cataggctct gtgcccgctg
      721 accacaagtg gcccagcaga atggcgaagt aagccagttg tccaaactgg gaaacgaata
      781 aaataaaagg aagctggaat cgggccaaaa tgagcggtgc taaaaagccg ctgatcatct
      841 gcgcccccat ccgcagcaac ggaacgagca ccgaagagaa gatcgagtct gtttcatgaa
      901 agaccaaaga cacaagtgcc ataatgtaaa gaatgtcggc cgcattggac atcgtctgcg
      961 tgccaagcaa ataggtaaag gaacgcttgt gcatataaat tagaatactc ctttgataat
     1021 gtggcttttt tacagccgaa taattaagtc catttcaggg ttaccctaag attgccggta
     1081 cttccgagat ccgtaatctg ataggaaatg gattttaagc cgagttggta caaggactgt
     1141 aaatcctcct taagacttcg ttccgtacct tgatagccaa aagtaattga cgtttctccc
     1201 ttagttatca tcttccgaac ctgttccttg atgtcagctg atgatttaac cagtcccttg
     1261 ccgtcttgca atggatattc caggttattg tacagttttt gatacacggc agcctttgct
     1321 cctccggcag ctatcaatgc cgataaggtt tcgcggtacg atgtgttcgc ctgaggatat
     1381 tgtttaaccc acgaatgatc ccgccgcatt tctgaatccg tcagcagata atatgaagtg
     1441 cttacctcgt tcgcgcgatc gggggtcggg tcatcccatg tcgtatccat gtgataccat
     1501 cggccatcta ataaaacaag attccatgca tgcaactgcc ctcctgctct accttccaca
     1561 atccgatttg taatccctgc tcgttcgagc attttataag ccaacagcga ataaccctga
     1621 cagaccgtgc ttcccgtttt cagaccatca taggctgtgt acttttgctg tgcttcatca
     1681 tacttcaggc gaacgacgat ccaatcatgg atggccttca ccttttcatg atccgtcatt
     1741 cccttcgtaa tgatatcccc cagcacagct tgcactgtgc tatccacata tgccgtctgt
     1801 tccttcgttt cccggtagct taaacgaatc gtaacctggg cggaggtggt tgtgcctgta
     1861 tagctgaatg cgtagctttt gatcgtataa ttcacatacg gatcgctctc catcgcctgt
     1921 tggatggctg tctgtaactg ctgcttgaga ccgttcactc gcccttgata tgtaaaggtc
     1981 agcgtttcac tccgcgtagc cattgcctgt aaaagcttgt tttgaagctg ctgcgatgat
     2041 acggagggag tcggcttgac cgacgccgca tacacattgt tgccccactc tacagcctgc
     2101 ggcagcaaca cagccagcgc tgcacctgca accagacatt ttacaagcct aaccccgatt
     2161 tttctgttca tacagagcgt tcctgccctt cttagcatag ttgtaaacag ctctatctta
     2221 ccataaaaac agttgcccca aacgctctag ttttgtcggt tgcaggcggg tatgagtgca
     2281 tttaaaggca ggttgcgaca ccttactctg ttatataaca gagagggcta tacataaaca
     2341 tgtcgttcgc agagaaattt atcacagcaa tctagtactc ctcatgatat ggtactggca
     2401 tcggaagtaa atgatattga ttctcattct agatcagaaa ggctgagcac catggcagaa
     2461 tgtatctcac tccttcgtac accattaggt cagactgtgc gtttgcaatc tcttgcccct
     2521 cttcacccct cattgcgccg ccgtttaaca gacatgggca tcaacgaagg ctccattata
     2581 cgcttaaaaa agatcagttt attgggcggc ccaatcgtca ttgaatgcaa cggccagtta
     2641 gtcggcctcc gccaaaatca agtgaagcaa ctggaggtcg ttccgacatg gacatgatcg
     2701 ctcttttcgg taatcccaat acaggaaaaa cctcattatt caacaagttg actcgtacgt
     2761 atgcagaagt aggaaactgg tctggcgtca ctgtggaaaa gaaaacagga atcctgcgtg
     2821 acaagtctgc cgtattggtg gatttgccgg gtgcctactc tttactccct ctgtcgctgg
     2881 atgaaggcgt cgcaacccgt tatttgctgg aagaaccgcc tgcggcgcta attaacatcg
     2941 tggatgcttc ccagcttcag cgcaatctat atctgaccgt acaattattg gaatacggcc
     3001 gtccacttgt actcggctta aacatgaccg atgtagccga tgccaccggt cttcgggtaa
     3061 acaaggaact gttggctgat caattgaacg ttcccattat tccgatggtg gcacgtacag
     3121 gtagtggaag taagcaaatg cttgcttccc ttcgagaggt cagacataca tccaatgctt
     3181 ttcaactgga ttacggtcct gctgtcgaag ctgctattgc ggatatttgc agcttgctgc
     3241 cgcatacatc tgtgcctcag ctccgctggg ctgcactgca atgtctggaa aacaatccgg
     3301 tcgtcatgga atggatgacg aatgagacac tgcgtgaaca agtaactgca cgcatccagc
     3361 gctgcgagga agagcttctc agggaagggt atgccagcac ccctgctcaa catattcgtt
     3421 ttgtaagaac agcatggatt gctgagctgt gcaccaaggc agttgacaca tccaaactca
     3481 gaccgcacag cctgactgat aaactggatg cactgctaac tcatcggtac ttggggattc
     3541 cgatcttttt actgttaatg tacgctacct ttaagtttac cttcgattgg gcgggtacca
     3601 ttctttcaga tatgctggat gaattttttt cagggacact cagcagttgg attactgaat
     3661 tacttgttca attgaacgcg tccgctttta cgcaaagtct agttgtagac ggtatcgtgg
     3721 ctggggtcgg gggtgtgctt gtttttctac ctcaaattgc tattttattt ctgattatct
     3781 cggtgatcga agactctggg tatatggcac gggtcacgat actcatggat cgcttgatgc
     3841 aagccgtggg cttgaacgga aaaagcttca ttcccttcat catcggattc ggctgtaatg
     3901 tgccagctat tatggcagca cgcaccattg aacaaccaag agaacgcctc attacaacgt
     3961 tgctggtacc ctttatgtca tgctcggctc gcttgccagt ctatgcgttg tttgcaggtg
     4021 tatttttccc gtcgcatgcg gcgagcatta tcatgctgat gtatgtgtta gggatcatcg
     4081 tatcgcttat acttgccaaa attttttcca aagtatctat tttatcaggc gagccttccc
     4141 tctttatcgt ggaacttcct ccctatcggg tgccgcaggc tcttacttta tttcgcagca
     4201 catgggagaa ggtcaaaggc ttcgtccgta aagccggaac gattattctt gcaggctctg
     4261 taggcatctg gctcttgtcc aatttcggtc cgcagggctt cggcgtagaa atggatgaca
     4321 gcctgcttgc cactgttgga ggatggtttg cacctctatt ggcccctctt ggttttggca
     4381 cttggcaagc aggtgcttcc ctgctcacag gctttatggc caaggaagtt gtcgtatcaa
     4441 cgatgaatat tatttaccac gttcctgata tgcagggact ggaactacaa gtcagacagg
     4501 catttacacc gcttgcctct tttagcttta tggtattcat tctgttgtac gtgccgtgtc
     4561 tggctacggt agcggttatt cgcaaggaga cactctcctg gcgctggacc gcattttctg
     4621 tgatctatcc tttgaccgtg gcatatatca tcgccgtctt gatctatcag tgtggcagat
     4681 tattaggttg gggttaagtc agaccctaga gtatataaaa ggaagtggat tccatggtca
     4741 atatcattat tttattggtg atcctcggtt acagtgcgtg ggtgttggta agatttttgc
     4801 gaaaaagccg ccaaggcgcc tgtgctggct gttcatcgag caagtcatgc ccaggctgtg
     4861 ccgtgagctc ggtgaatgag gataccagaa aaacaacggc agctcacaaa ggttaaccat
     4921 agtcatctca caatggacgg atagcaagaa aaaacttggc gactgctctc taaatacatt
     4981 acagggagca ctgttagcca agttttttca ttgttactct attccttgaa aacattttaa
     5041 tcaggggtac taataagcta gtcatgttga tgtgctatat ataggcgttc aaggtcaatt
     5101 gtagatcttc ctgaatatgt tatccgaccg tttcgaagaa tggcaacctg gtctgctaat
     5161 ttctcagcta atcctataat atgagtagat aacaatataa ctctgccttc tgttagatac
     5221 tcccgtagta tacttctaac aatcatcact tgatcaggat ctaatccgtt agtcggttca
     5281 tctaatataa gaattctagg ttcatgtaag agcattgaag ctaatgcaac tctcttttta
     5341 gttccttgtg ataactcttc catttttata ttttgataat cttctaattt gaatctgtcc
     5401 agccatttag cgatgcgcat ttcgagttgg tccttcggta cctgtcgtaa ccccccaata
     5461 agtcgcatca tttctgatac agaaagtgca ggataataaa aagggaattc ttgtagatat
     5521 cctaccattg atttatagtt ttgattttca aaatcaatta tggtttgatt gaagcgaatt
     5581 gtaccttttt gtacctgatg gagaccagca attaaactta ataaagttga tttacccgct
     5641 ccattaggac ctagcaacac agtaatttgg tggtctggga catcccaatt taatccatgt
     5701 ataatttctc tggagccgta actgaaagaa acttgatcca gttgtaaaaa tgatgattta
     5761 tgttcttggg tcatcgttga ctcactccta agataccttt ttataaaaaa gtataaatct
     5821 tgtatagatc ataactgata tagctacaaa taatacttta tgaaattgat gaagatacaa
     5881 tagtaatagc atgctcattg ctatgaccca gctcccaaga aacttgatac ggtaatttcc
     5941 taaatagtct atggataaaa atttgtaacc caaaggcatg cccaaactaa ttaaagtagt
     6001 tgagaggaat atactccata tagtttggat tgataaaatc actggactaa tctgtaaata
     6061 aatcccccaa aaccactgat gcataaaaat aattcctatg tttaaaacac ataaaattaa
     6121 ccatttagtg cgcagcatct tcttccaggc aaataacgtt gctttatata ttagtagtcc
     6181 tttttcctct ataacaagac tcttgacagc ccagatatca acagcaaacc atgataatat
     6241 cgcgctactg attgaaagaa taaacgggct ttctctaata atataagagt ttaaaacttc
     6301 aattcccaaa gctaaaataa aaaaagaaaa caggttaact ggcctaataa taaataacaa
     6361 ttcctttttt aggagtggac attgagatag ccatccacgt cgtcccaaaa ctttttttga
     6421 accatgatac tgtaaaaaaa cagaccaaga gcgttgtgca aaatagagag ttatatatcc
     6481 catgcttata cataacaaaa tccaagtcaa aatacgtact gacagagaca ttggcaatat
     6541 gaaatagact acaaccagtg atagaaagaa aaagcttatt gcatagccag agaactttct
     6601 aaataacgtt atataccaaa atatctctgc taaaagcaca cctaagatca atcctgaaac
     6661 catactaaaa atgtaattat gatgaacatc ccataagatc tggccaacta cgatccataa
     6721 aagtaatatt agaaaaggaa ttttctttac aatagtatat tgggttaaaa accaatttcc
     6781 ctttcctata gaccacaaaa aacgtacttc ctccacttta gaaatcgata tacttatacc
     6841 aaattgaatc aaaaaaccaa tgattccata tatgatagcc cacatcattg ctttaatacc
     6901 caagctgttt aaccttaagg tagcattagc taatccattg ggaattaaaa ttaataaaaa
     6961 aatgaataaa gcagcctcca ttttagttag ctttctgagt tgctttagat acaatatttc
     7021 acataacttt atacttgtca tttttctcgt ctccaagtca caaaactggc tcaacctgaa
     7081 aatcagtttt cttcaaatta tacaaatcaa aatatttacc ttttaaaccg atcaattcct
     7141 gatgatttcc ttgttctatt atttcccctt gatcaagcac aattattcta tcagctcgtt
     7201 ggactgtact aagacgatga gcaataatga tctgtgtaca atgtctttct tgtaagaaat
     7261 ctgttatcaa ttgctctgaa acactatcaa gcgaacttgt tgcctcatct aaaaggagaa
     7321 tttgaggttc tgccaaaaaa gcacgcgcca ataaaatacg ttgccgttgt ccccctgaaa
     7381 agtttaatcc gttctcggaa acaacagttt gatagcctaa agggagactc ataataaaac
     7441 ggtgaatatc ggcttgcttt gctgcccgaa ctaccatatc tatggtacaa tctccattgt
     7501 ccatggcgat gttatccaat atagaaacat tgaataattt tgtctcttgt agaataacac
     7561 ctattttttg acgaaactct ctcaaatgcc attgatccag cgggatatta tcgacgctga
     7621 cttctcctat tgaggcctta taaagtccta gtattaactt cgccaaagta cttttacctg
     7681 agcctgatgc acccacaatt gcaacctttt cacctgggaa tatttcaaga ttaatatttt
     7741 ttaaaacata ttttccaaat cgatgataat taaaggaaac atctttaaac ttaatatatc
     7801 ctttaaaagt atggttcggt ttatggttac ctgaaggctc ctctacattt tcaataacat
     7861 cttgaattcg ttgaatatat gtgcccacag tgacaagttc actaagagtc gatcctaagg
     7921 aaacaagcgg taccataaaa gcagttgaca atgtttgtaa gcccaggagt cccccgaaag
     7981 ttatccatcc ctcaagcaca taatggaatc caatccatag aattagtagg ggaaaaataa
     8041 actggatgct aactgtcatg gaatcaagtg atgcattcca aatgacacgt ttttccgtat
     8101 tagttagttg ttttttaaaa agctcctccc acttcttaaa tactctactc tcaaacccta
     8161 aaacttttat gtctgtaatt ccatgtatat gttctgataa aaaaccatgc atctcagcct
     8221 ggctcgaagt ctcctttcga gataaacggt gagtagtaaa agaacttaaa acggtaataa
     8281 gtaacaatag aaaacctata attgtaacta ataatccaat ttgccatagt agattaatca
     8341 ttaaagctgc ataagttata agtaaaagcc cgtcaataaa aatagttata actcgattag
     8401 ataataccct tctaattgtt acattagagt tagctctaaa taccaattct cctccttttc
     8461 gattttcaaa gaactcaaaa ggaagtttga aaagcttagc gataaattgt gtcatcatag
     8521 aagtatccat ttgggattgt aacttggcaa tcatgtaacc ccttaaaaat tggaataact
     8581 gtgaaaatag aaatattgta aaaatagccc accccaatgg gaccagaaaa gaattatttt
     8641 tggattctag taagttgtca acagagaatt gggtgatctt aggtattaaa acacctaatc
     8701 cttgaagaag tattgagacc aaaaatacag aaataagaag tttcctactc ttaaaggcta
     8761 atttgatata gaacatccat tttggccttt ttcttttact ccgaaaatcc tttaacggga
     8821 ttaaagaaag tgcaaaaccc gaatacttct ctgtgaattc tttgagagga agaatgagtc
     8881 ttccaaaagc cggatcaagg attattacct ttttcttttt tattttctca agaaccacaa
     8941 aatgctggtt atcccataac aaaatcagag gagcgattag ctcatttaat tgagatgcag
     9001 ttgcccgata tcctcgtgat tttaaatgat atgtacttcc tatttcttga agttgttgca
     9061 tagatatacc tgcgcgtact gcaccaacct gatttcttaa ctctgttaaa gaaatattat
     9121 gtccataaaa acccaaaatc atagccaagc tggctaatcc acattcacta tgttccatct
     9181 gttcaataaa aggtactttc ttattaaaat tcagaggaat gcacctctat accttctgtc
     9241 aaaaaaacta agccgtaatg ataagcgaat ataccaatct caactcttgt ttttatattc
     9301 catttctctt taattgaagc cacaatttcg gcagtacgtc tcatactgat agataaattc
     9361 tgggagattt cgctgtcttt gtatccttga gctatacaaa ttgcaacttt ttgttctttt
     9421 ggagataaat tatgattttc tctcaatttt cactccccct atgtttttta tgaatatttt
     9481 ttcataatta aggaagaaat tcaatacata ttcaatgaat atatttgtaa aattaaaaat
     9541 aaaatcgttt tttttgaatt tttataggtt tttgcattaa aatgcacttt tatgaagtgc
     9601 aaatttttag ggaatatgat tatcattagg tttgtcttat atcactacat tcccgagagg
     9661 agtaaagaat aatgacaaaa gaagaaatga tccaagcatg gaaaaatcca aagcttcgtg
     9721 tagctggaga agggattgag catcctgcag gcgacgcttt ggtcgagttg agcgctgacg
     9781 agctttctcg tgtacatggc ggtttaggag tgcaaccaga ttctactcca actattactg
     9841 ttactgttat tggtgtcaca gtactagttt gttttccagg gcatgccgga taaaataagt
     9901 gaatgccact caggtatacg ccttaattgg cgtatacctg agttatttta tttcctaaaa
     9961 ttgagttttt taacttcata taaacgagga cggggtattt atgaaagagc agatcatgcg
    10021 tgctctcttt ttacaagaac gtaagaacct ttttgatcaa gcctttcaag attttaatta
    10081 taaaaattgg aaacaagata aagagaagac gacagaactg attgacgaat ggtttaaatt
    10141 tgctcttatt agtacagaat ccaaaaagga agctcgattt aaagctttaa gtatgaatga
    10201 agaaatattt ggagccttga ttcaatctac ggaaaatctt aaatgggatg agaactattt
    10261 aacggttatt aaagagtatc aagcagattg gtttcaagtt ttggaagagg ctctaaaaat
    10321 gaatgaaaat caaccagttt tgcaaaatga gtctcgaaca atggatattc ttgttcgtcc
    10381 atttattatt tggtccagaa atcaattaaa acagcactta tgcaatatag ataatactca
    10441 ggattttatt ctacatgaga gtacgataaa ttcggtcttg catacattat cttttcaatt
    10501 gacccaaatc gctggtcgat catttgtctt agaactaaat atagctaaag ctttgggaga
    10561 attagaaggg ctaactccgg aggaacgatt tatctctttc attgagaaaa aatttgtagg
    10621 acataaacaa cttgtatcat ttttttctga gtatgcagtt attgcccgga ctttagctga
    10681 aagaactatg ctttttgtaa atgtaacaaa agagacgtta gaccgttatc tcctaaacag
    10741 atctatgatt atcgatacat tttctttaca ttcatcagaa cttatacgta tcgatgctgg
    10801 gttcggtgat tctcatcagc aaggtcgcac agtaatgcgg ttatatcttg caaacgggca
    10861 atcgtttatg tataagccaa agccattaga tatctccctc cattttcaag aattaattca
    10921 atggtttaat gataaagggt tttctccttt tctccaaaga aattctgtta tcgcattaga
    10981 cggttatggt tatgaaaaat ttatcgaagc aaaaccttgc aaaactgaag aagaaattca
    11041 atgtttttat acacgtttag gagcgctttt agccattata tatgtactgg atgggaccga
    11101 ttttcatttt gaaaatttaa ttgctttcgg ggagcatcca atgctgattg atttggaaac
    11161 cctctttcac aaccaggtat atcataatgt ccccgattcc gcagatatag aagctcagtt
    11221 taaaatctgt aattctccat taggcacttc actcctccct atcttgtttc atcaagatga
    11281 taaaggattt ggacttgaat tgagtggtgt aaatggggaa cggcaaatga caccctaccc
    11341 agtgttgagt ttagtagatg taaatactga taatatgaga tacattagaa agtctcagtc
    11401 cacttcaact ggtaacaatc gcccttcatt ggaaggagaa tttaaaaatg caggtgacta
    11461 cactgctgaa attgtaaatg gtttccaatc attatgttcc atgcttcttc aatacaaaat
    11521 ggatttacta gtcccaacaa gtcctctctt tagttttaat aatacgccag ttcgtatcgt
    11581 attgcgatca acacaatttt atacaaattt ccttctcgaa tctcgacatc ctgattatgg
    11641 tcgcgatgct ctaaatcaag agaatctact tgatcggatt tggttttctt ggctggatga
    11701 tcggattatt tcttcagaac tgcaagattt acgagcagga gatattccat atttcattgg
    11761 tactcctaat tcacttgacc tttgggatag ttatggcaga tgtataaaag atgtgtttac
    11821 ccgaacaagc atgtcaatag tagaagatag attgagatcc ttaagtactg acagtatttc
    11881 tttatacagc gattggatct cttcttccat agcaggctca tcattaggaa aacatgtaca
    11941 taaagtacat gctccctctc aaaatgaaaa agtaatgaca agcgactaca gtccaaaacc
    12001 attacactct gaaaactttc ttgagacagc aaaaatcctt ggcgatgagt taattgaaaa
    12061 atcagtgttt agccaaagca aaaggtatgt aacttggatt ggaatgaatc taaattatcg
    12121 cggacaactt tatttgtctg ccttaagccc tggattatat gatggtacgg caggcattgc
    12181 attatttcta gcatatctcg gaaaaatctc aaaagaggag aagtacacca acatagctct
    12241 agctgcactt gaaacaacgc taagtaaaat acctgtacac ctaaaattcc catcagcctt
    12301 ttatggccaa gcttctctct tatatactct ctctcatttt gagagtttat taggttttaa
    12361 cgatgcttgg agcaagcgga aattggacat tataagtaat ttggaagata gcatagacga
    12421 ggatactttc ttcgatctct taggaggttc ggctggagtt attcacgttc ttttaaatga
    12481 atatagtctt acaaaatcgg ttaagactct agaggtagca actcaatatg gagagcactt
    12541 gttaaaacat ggagaaaaaa ataatgagat gatttcatgg acatctagtg tatctccaac
    12601 cccctacgta ggctttggcc acggtagtac tggtattgct tcagctttgt ttcgtcttgc
    12661 agcagttact aaaaataatt gctactatgc tactgccgag aaagcatttg ctcacttaac
    12721 agaatcctat tctccaaact attttaactg gattgatcaa gatattaagg agaatcatga
    12781 tctggctaat tggtgtcatg gggctagtgg aattggcata ggattaacct tatgtatgcc
    12841 ttatttaaat tcaagtttaa tacctgatat cgtccaaaat atcgaaatag cagttaatac
    12901 aactttaaaa tacggattta ataaaagtca ctgcatttgt catggaagtc tcggaaatat
    12961 tgagttatta attttagctg gacaagctct taaccgtcca gagtgggttg cggaggcaaa
    13021 gaaacaaggc aacattgcat taagttattt tttcgagcat agtaaattta agactggcct
    13081 gcccactgcg ttagattccc aggggttgtg gctaggtttg tctggaatag gttatcaatt
    13141 catgcgtctc cactcgttaa cttccttacc aagtatcctc tcactacagg agccacttta
    13201 taaggagtcc tcttgcacta aacgtcctta aaattcaaaa gccataataa aggtgtcctc
    13261 atcaggcaac ccttattatg gcttttatta acgtaaagtc tattcagcga tagaccgcca
    13321 attgctcact tagctcccgt gtgtgtagat aaacttcacg gtatagctcg tataagcctt
    13381 catactgtgc cacacgttcc ggatttggcg tatatcttgc tgcttcacgc agaaaagctt
    13441 cagcgcacgc ctgcagcgat tcaaaccacc cgctaccata tgcagccagc atagccgctc
    13501 ccaaggcagg accctgctca ctttccagct tgacgatatc cgcgttaaaa atatcggcct
    13561 gcatttgcag ccatgtctca ttacgcgcac cgccgccgat ggaaatcact tcattcaccg
    13621 ttttgcccgt gcctctgaga atatcaatgg attccttgag cgaaaacgta attccctcca
    13681 gcactgctcg tgtaaaatgc ggaagcttat gccctgcatc catcccgata aagctgcctc
    13741 gaatagctgc atccggatga ggggtacgtt cgcccacgat ataaggcgtg aacaacagcc
    13801 ctcggctgcc cggctcgatc gagtttacat cctccaacag cgcatcaaaa gaatgttccg
    13861 gcgcaaaggt atccttaaac caggtcaagc tatatccggc cgcgagtgta acccccataa
    13921 tataataagc atcctgctca ccatgattaa aaaaatgtgc ccgtccctga acgtcgatat
    13981 ccttgcgttc ctcataggaa agcacaactc ctgaggtgcc gatactgcac aaggtgcggc
    14041 cttcgctcaa aatgccggca ccaatcgcgc cacatgcgtt gtctgctcca cctgcataga
    14101 ccttggtttc agacgaaagc ccactctgct ccgcaatctc cggcaataga gtacccgtct
    14161 ggtcaaagga ttccaccagc ggcgggaaca gcgacaacgg cagatcaaac gcagctgcga
    14221 tctcttcgct ccactgcttg ttcgcgatgt ctagcagcag cgtgcctgcc gcatccgaat
    14281 actccatcgc caaccctcct gtgagacagt agcgcacata atctttaggc agcataaaat
    14341 gggccgcacg agccagcacg tctggctcat gctcctgcac ccacagcagc ttgggtagcg
    14401 tgaagccttc cagcgcgcgg ttgcgcgcga tacttagcag cgctggcccg agctgttctt
    14461 caatacggcg gcattgtgcc gttgtgcgcg tgtcattcca tagaatagct ggacgaagca
    14521 cttggccttc cttgtcagtc agcacaagcc cgtgcatctg ccccgaaaag ctgatgccgt
    14581 ccacagcatc tgttccggag attccggcct tctctacaag ctctttcaac gatgctaacg
    14641 tcccacgcac ccagtcttca ggctgctgtt cgctataccc tgctttcggc tgatgaagag
    14701 gatatgactg agaggtttca taagccacct gccccttacg gttgaccagc accgttttga
    14761 ccgcactagt acccaaatcc acgccgatga catagcgctc cagctcctgt tttagcttct
    14821 cctgcattgg agttcctcct tccctgtgat cgtacgaccc ttattcatat ataaattccg
    14881 gcattaatca gccaaaatgt attgattcaa tgttgctttc agatattcct gacgaccgga
    14941 cacgtttttg cgtggtgctt cgttcgccag agcatattca gccagggaag caagcgttgc
    15001 ttttccggat acaatgtctg ctccaatgcc ttctttaaag ctgctgtacc gcttctcaat
    15061 aaagtcctca aacacacgat cctcgatcag tttggcggct accttcaacc ctttcgcata
    15121 cgtatccata cctgcgatgt gcgcgaggaa caaatcttct ggttcaaacg atgctctgcg
    15181 caccttggca tcaaagttga taccgccacg gcctaatcct tcattttgca gtacttcata
    15241 catggttagt gtggcatcat acagatcaac cgggaattcg tccgtatccc agcccagcag
    15301 caaatcacct tggttggcat ccagggaacc caacatgccg ttaacccgtg ctacacgtac
    15361 ttcatgatca aaagtatgac ccgccaaagt ggcatggtta gcttccagat taagcttgaa
    15421 atgctgatcc agatcatatt tttgcaggaa ggcaatcgtc gtcgccgcat caaaatcata
    15481 ctgatgcttg gttggctcct tcggttttgg ctcaatcagg aattgagcgt caaagccgat
    15541 ttcacgcgcg tagtccacgg ccatatggaa catccgtccc agattgtcct gttccaactt
    15601 caaatctgta ttcagcagtg tttcatagcc ttcacggcct ccccagaata cgtagttatc
    15661 tgcgcccaga cgtttgccta cttccagtcc ttttttaatt tgggcagctg cgtgtgcgta
    15721 tacatctgca ttgcaagtcg tcgcagctcc atgcaaataa cgtggatggc taaacatgtt
    15781 cgccgtgttc cacagcagct ttttccccgt agccttcatg tgctcctcaa tcagatccac
    15841 gatggtatcc agattgctgt aaaattcctt cagtgacgcg ccttcaggag caatatccac
    15901 atcgtggaag gcgaaataag gtaaattcag tttatccagc agctcaaagg cagcttccac
    15961 acgtgccttc gccaaatcaa gtccggtaaa cttggaccat gggcgttccg cagtctctac
    16021 tccaaaagga tcagagccgc ctgcaaccag tgtatgccaa taggccatac taaaacgcaa
    16081 atgctcctcc atcgtttttc ccgctactat ttcctgagga ttataaaatt tgaacgcaaa
    16141 aggattatcg gattgcttgc cctcaaagtt aattttggat acttgttcga aataagccat
    16201 tataagttcc tcctttgtag taaacgttta caaaaacgat tctagcacag ccaagaaact
    16261 ttgtctattg cttaaactaa gtttattttt atgatataat aacgggaatt acatcaacag
    16321 gaagggaaat aaccatgaat gttactggcg atcaggcgct tgtcaaaaag ctgaataaat
    16381 ccattgtatt ggagcgcatc cgccttcatg cccctctatc ccgggcacag ttatccagtc
    16441 aaaccggatt aaacaaggcc accgtgtcca acctggttgc agagcttatc accgatggat
    16501 tggtgtatga gacaggatta ggagaatcca gcggtgggcg caaaccttta atgctgctgt
    16561 tcaacagccg tgcaggcttt gtacttggta tcgaggttag tgtacagtac atcaagggcg
    16621 ctctgaccga tctggcaggt accattgaaa cagagcttac cctttctcta acccagcatg
    16681 atcctgactt tgtcatcgaa caaatccgta agctcgttca gaagctcatg caggtcaccc
    16741 ctccctcccc tcacggtatt gtcggcattg ggttgggggt accagggatg gtggatgaaa
    16801 ccggaaatgt tttattcgca cccaatctgg gctgggaaga ggttccgctg cggcagcagc
    16861 tggagacaga gctgggtctt cccatagtgg tggataatga ggccaacgtc ggtgcacaag
    16921 gcgaattgta ctatggtatg gacgccgatc atcggcaact ggtgcgggat ctggtctaca
    16981 tcagtgcagg ctccgggatc ggggccggaa ttatcattga tggcaagccg tatcaagggg
    17041 cttggggata cgcgggcgag agcggacata tgtccattga ctggaatggg cgcctctgct
    17101 cctgcggcag ccgaggctgc tgggagctgt atgcttcgga gaaggcgtat gtagcatcca
    17161 cattgaagct gcccgcacat aatacagcgg gattattacc gtttgcccag caaggtgatg
    17221 tgagtacatt aagcgtcctt ggtgaaatcg ggcgatattt gggtgtgggt attaccaaca
    17281 ttgtgaacag cctcaaccct ggcatgctta tcattggcgg cccactcgcg gaagccagac
    17341 cttggttgga gcaaagtatg cgtgaagtga ttgacgaacg tgccctgccc tatcaccgcc
    17401 ggcaactaca gattcgtttc tccacgcttg gcagccgttc gacgatgcta ggtgccgcct
    17461 atgcggcaac agctcctttt ctcgggcgtg tacgtgtatc tttataaaaa aaagcgtaca
    17521 ggaacactca ggttcctgta cgcttttttg cttaggattt tgcaaaatcc gttgtctgct
    17581 ataaggttgg attaagcgtt caacactttt tcaaacttgg ttttgttcat accggaaata
    17641 cgttcttctc cgatcaaagt caatggaaca gcgcgaatgc ccatatccca aacctcttgc
    17701 gcaaaagctt cattggtttc aatgttgcgt tcttcgtatt cgacaccttt ttcagccagg
    17761 tagcttttta cttgacggca atgcggacag tttgtagatg tgtaaactat tgctttttcc
    17821 atgaatatca cctcatcatt tattttgtta cattatattt attcatactt ccaaatatca
    17881 ttacagggca agtgcgctgt gctccagact ttcgatgtat ttctcgctgt ccatagcagc
    17941 catacaacca ctacctgctg cggtaatcgc ttgtctgtag cgtgtatcct gtacgtcgcc
    18001 acaagcgaat acgccaggca cgtttgtttc ggaggtaccc ggattgacga cgatataacc
    18061 gttcgcatcc gttgtaattt gtccttcgag gaagcctgta ttcggatgat gaccaattgc
    18121 cacgaatacg ccgctcactg taatgatttc ctctttacct gttgcgttgt ttagcacttt
    18181 caagccagtt actccgtttt cgtctgcaac tacttcgaca ggagtacgat tgagcgccca
    18241 ttcaattttg ctgttcgcac gagcacgatc ctgcataatt ttagaagctc tcaattcttc
    18301 acgacgatgt accaacgtta ctttggaagc aaagcgagtc aggaaattag cttcttccag
    18361 tgcagagtcc ccaccgccga taacaacgat ttctttgccg cggaagaaga acccgtcaca
    18421 ggtagcgcaa gtgctcacgc cgcgtccgat attatcttgt tcaccgggta tccccaggta
    18481 tttggcagtc gcccctgtgg aaataatcag cgtatcggta accagttcac ccaaaccttc
    18541 tacatccagt gtaaatggac gagcagttgt gtctaccttg ttcacccagc ctgtgcggaa
    18601 ttcagcgcca aaacgctccg cttgcttacg catattatcc atcaaatcag gtcccatgat
    18661 tccttcagga aagcctggaa aattctcaac ttctgtagtc gtggttaatt gtccacctgg
    18721 ctgtggtccc tcgattacca gcgggttcat attagcacgt gccaggtaaa tagcggcggt
    18781 caaaccggca ggaccggtac ctataataat ggacttgtac atatcttggt tcctcctaaa
    18841 atatcataag tattatatag cgagttttcg gtaccgggcg ctgggctgct gcatatactc
    18901 taaaagtagt gccagcagaa gctcatccca aaaagtggac acccggatgt tgtaaaaacg
    18961 aatcacttgt tttctagctt cttatgactt agactgattc taaatcctaa tttcattatg
    19021 cggaaagagc tgtaaacagt caaatgaagt tttcatgaag cgaagtttaa agataaatga
    19081 ggtatggagg gattatcccg attatgaatg acgttttcgt aggtagctta atttctgccc
    19141 tgtccaccgg actcggcgcc gtacctatat tgtttatgcg taatatcacg catcggcttc
    19201 gcgatgttct gctggcttat gccgcaggaa ttatgacctc tgcatccgtg tataacctta
    19261 ttccagaagc gatccagcat tccaattggt tcgtgctgac tgcgggaatt ttgcttggtt
    19321 gcctcgtatt actggtgatg gaaatgtata tcccccatgc cgatttggag gacccggatt
    19381 ccaaaacttt tcaattggag tccaaatctt ttctcattat tgcagctatt acgttgcaca
    19441 acttgccgga agggctctct gttggggtca gctacgcgag tgagactcag aatctaggca
    19501 atctcattgc cttctctatc ggtctgcaaa atgcccctga aggctttatt gtagcgttat
    19561 tccttgtgaa tcaaaacatc ggtcgtttca aggcattggg cattgctacc ctaacggggg
    19621 ctgtggaaat catcaccagt ctgatcggct tttatttaag cagctgggtg aacggactgg
    19681 tgccgtatgg ccttgctttt gccgccgggg ctatgatgtt tattgtctat aaggaactga
    19741 ttcccgaaag tcacggggac ggtaaccagc ggatcgccac attctctttt attcttggct
    19801 tgattacgat gatcgggcta accgaatggc tatagccgcg cagcacaaaa aggctgcttt
    19861 tctgtctgta attcagacag aaaagcagcc tttttgccat gttcaaatga tgggacctca
    19921 ttttttttgg ttcatggaac gcagtgcttc acggtactgt tcgtccttac ttttggaagt
    19981 ccctttcttc ccattggatc ttggggaacc tccatccttt tctccgtcct ttccagcaaa
    20041 accacgcaaa gctgcacgat aatcctgatc cccgtaagca ccttctatgt tcttgcgatc
    20101 tttttccacc ttcatatccg tttggatatc aggcaacttc tgatgctcct tggcacgatg
    20161 ttcttcaact tcggaatcct taggcggcat ctctccgtta tgttccgtta attcatgcgc
    20221 cttgggttcc acttgcacag gataaggacg tttacttctt tgccgggatt cctcttggct
    20281 ggggcgattc ttggccgagg acttgcgcgt catctttgtg ttaaatacca gcaaaaagat
    20341 caaggcaacc acagctactg cgataaaagc aatggtcatc ggcggcctcc tattctcttt
    20401 cagcgctacg gtaccgtccc gccatctcag caaccctttt gcccaaagag cgacctaacg
    20461 caagatcatc gcccgttgga aggttgggcg gtccatcggg gtctgtctcc accggacatg
    20521 ttacccctac accgtaatag gagccgtaga gcgcattttc cgtgatgcta gcgggcaggc
    20581 ctacaataat catgccttga tgaagcatag gagtaatcaa attcaaaagc gttgattcca
    20641 atccaccatg aacggtagca gttgtgcaaa atactgcacc gattttgtcc accagcttgc
    20701 cctgcgccca caaatatccg agcttgtcaa tccagctctt cagaccgctg ctgatggtac
    20761 caaaatgacc cgggcacccc catatgatcg catccgcgct tactagctca ttcacatcgg
    20821 cctcattcac atgctttagc gccacttctg tgtgattcag gcgtgctcct tctgcgattg
    20881 agcgagcgag acgttcggta tgtccatttt cactgtcata tacaatcatg attctggtcg
    20941 tcattatgcg catcatcctt tatcagcaag atcatccttt tgcatacgct cttaaccttt
    21001 cctagaatcc atctgaatat tatgaatcgt ttgacgcata ctttgaacat ccaaaaacac
    21061 taaggaggca tgcacaatat gaattcgcgc gccatattag ttaatctgct cgtaatcatc
    21121 attattctcg caggaggtgg agccgccgcc tattactaca atcaatccgc caactacata
    21181 aaaaccgaca atgcacaagt aagcggacaa gcagttactg ttgcctctcc aagcggagga
    21241 aagctcacgg gctggaacgc tgaagttggt aaaacgtaca ccgccggcag ctcgcttggt
    21301 agtgtagagg gaggcggaag ccggatcagc gttacgatcc cgactgacgg taccatcgta
    21361 cagcaaactg cagtcaacaa ctcagttgtc ggggcgggca cacctttagc gaaagcattt
    21421 gatctgaaca atctttggat tactgccaat atagacgaaa cggctgtgca ggatctccaa
    21481 gtaggccaga ccgtagatgt gtatattgat gcttacccag atacatccct gaccggtaaa
    21541 ctcgaaaaga tcggtctggc aaccgcatcc accttttcac tgctgcccac ctccaatacc
    21601 actgccaact ataccaaggt gacgcaggtc gtgcctgtca acatttccat tcaaggttac
    21661 aagggcctag ggattatccc gggaatgagt gcaacgatca gagttcacaa gtaggaggct
    21721 gtcatggatc aaaaaatgtc cgtcggacgc attctgtccg tgctactgct aggcgccttc
    21781 atttcgattt tgaatcaaac gctgcttaac gtggctattc cacacttgat gaatgacttc
    21841 aatgtatctg ccacaaccgt tcaatggtta tccaccggat atatgctgac aaacggaatt
    21901 ttgattccta tcactgcttt tctgattgag tcattcggaa cacgtgcact gttcatctcc
    21961 gcgatggggt tatttactgc cgggtctgtc gtctgtgctg ccagtaccgg ctttgcgcct
    22021 atgctggttg gacgcgtgat ccaggccagc ggagcaggca tcatcatgcc tgtggtcatg
    22081 aacgtgttcc tgactgtgtt tcctccagaa aaacggggcg ctgccatggg tactatggga
    22141 atcgccatga tgtttgcccc ggcgattgga ccgactttat ccggctatat tgtggagcat
    22201 tacagctggc ggctgctatt tttactcgtt attccgctgg cggtcattga tattctgttt
    22261 gccatacgct ggctcaaaaa tgtatccaag ctaacgaaac cgaactttga cctgttggga
    22321 accatcttct ccacccttgg gtttggcttc ctgttgtatg gctttagttc ggctggagac
    22381 aaaggctgga gtagcaatac ggtaatcctt acactcgctg ccggggttgt gtttattgta
    22441 ttgtttatcg tgcgcgagct aaatatgata cagccgatgc tggagttccg tgtgtttaaa
    22501 tataatattt ttactgtatc aaccttagtt ggggctaccg tcaacatgac gatgttcggc
    22561 gggatgctac tgctgccaat ctatttacaa aatatacgcg gctttacacc gctgcaatcc
    22621 ggtctgctgc tgttgccggg tgcactgctg atgggtgtga tgtcaccgat atcaggggca
    22681 gtatttgacc gtataggcgc aaggccgttg gcgatcattg gactgatcat tacagcagtc
    22741 acaacctggg aattcagtct gctgaccgat gccaccacct acggacatat tatgatcatc
    22801 tatacgattc gcagcttcgg aatgtcattg ctgatgatgt ccgtccagac cgaagggcta
    22861 aaccagctac ctgcccatct cggcagccat ggtactgcca tgtccaatac agtacggcaa
    22921 atcgctggat ctatcggtac cgcttggctt attacggtaa tgagtagccg gactacagtt
    22981 catatggcag attatgcgaa tgtcgctacc acagcgaatg cttctgtaac ggaaggcgta
    23041 tcgcaactgg gacaaaccct tgcacaatcg gcgggtattt ctgcggaaag cggctctgca
    23101 ctcgcgctac aacaggtata ccgaagcgct gttacagaat cgacgatcca tggcattaat
    23161 gatgccttca tcattgcaac cgggattgcg ctggcgggat tattgttttc cctgttcttg
    23221 cggcgatcta c
//
