LOCUS       NC_017542              24064 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Paenibacillus polymyxa M1, complete sequence.
ACCESSION   NC_017542
VERSION     NC_017542.1
KEYWORDS    RefSeq; complete genome; complete replicon.
SOURCE      Paenibacillus polymyxa M1
  ORGANISM  Paenibacillus polymyxa M1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Niu,B., Rueckert,C., Blom,J., Wang,Q. and Borriss,R.
  TITLE     The genome of the plant growth-promoting rhizobacterium
            Paenibacillus polymyxa M-1 contains nine sites dedicated to
            nonribosomal synthesis of lipopeptides and polyketides
  JOURNAL   J Bacteriol 193 (20), 5862-5863 (2011)
   PUBMED   21952539
REFERENCE   2  (bases 1 to 5864546)
  AUTHORS   Blom,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2011) Cebitec, Bielefeld University,
            Universitaetsstr. 25, D-33615, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 01:49:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,687
            CDSs (total)                      :: 5,531
            Genes (coding)                    :: 5,427
            CDSs (with protein)               :: 5,427
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 45 of 104
            Pseudo Genes (incomplete)         :: 71 of 104
            Pseudo Genes (internal stop)      :: 16 of 104
            Pseudo Genes (multiple problems)  :: 23 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:14:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1376078
            Orig. end                         :: 1400142
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE577054.1.
            Accession number for plasmid pPPM1a in this genome project:
            HE577055.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24064
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="5"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24064
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24064
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14064](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14064
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    27..45
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.79"
                     /tool="antismash"
     misc_feature    complement(52..65)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            286..1206
                     /locus_tag="PPM_RS05945"
                     /old_locus_tag="PPM_1125"
     CDS             286..1206
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="PPM_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1125"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013369845.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDNLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERIDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTEGEVQTAEIAFEVNDAEQAYTLAGAGRVEGNQLLLHLEREQIAEMNSLLAANGVK
                     VYAISPVARTLEDQFLEVTGGGSIG"
     gene            1199..1981
                     /locus_tag="PPM_RS05950"
                     /old_locus_tag="PPM_1126"
     CDS             1199..1981
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="PPM_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1126"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_013369846.1"
                     /transl_table=11
                     /translation="MADFFKLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIVLVLMVTLSSWLMLSKDAPAGSVPLFSDPVSYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNSIGLFSTDRFEWTQYVLFTHMDLKKYLDM
                     PPGTVTSDLTFSLTVLAAYYVVFIAIAWVVFVKRDVST"
     misc_feature    2114..2130
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2200..3285
                     /locus_tag="PPM_RS05955"
                     /old_locus_tag="PPM_1127"
     CDS             2200..3285
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="PPM_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1127"
                     /product="AI-2E family transporter"
                     /protein_id="WP_013369847.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTSGIVMLLLIIYLGTKVSFIFSPLVSLVSLLIVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFLFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGLMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIVAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYHLFLERRVEDIME"
     gene            complement(3325..3786)
                     /locus_tag="PPM_RS05960"
                     /old_locus_tag="PPM_1128"
     CDS             complement(3325..3786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="PPM_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1128"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_013369848.1"
                     /transl_table=11
                     /translation="MFKESKKKLSTPATDTLLANGTSFEGTIEAEANIRIDGHFQGDIY
                     STRTVVIGESAVVRSDIIARDVILAGKVFGSITAEGRLTITPTGELYGNTATPTLVISE
                     GGILNGTSQMNQTMEAESPAAIEKSYDENQSSFSQDNEDSQASLQPEAG"
     gene            complement(3832..4863)
                     /locus_tag="PPM_RS05965"
                     /old_locus_tag="PPM_1129"
     CDS             complement(3832..4863)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /function="membrane proteins related to
                     metalloendopeptidases"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="PPM_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1129"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_014599540.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSAAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATSIRERL
                     QRVTELEQQMQQFIRKHGNSSSASSNKSTITPLSWDTSGHTGGELIAVHENTALLARQV
                     MDDFQEIEALLDTVERTVPRSIQQANAVQQNLERQQAAQLLQTRRLALAEQGRPSIWPV
                     GSRRMTSSFGYRSDPFTGRSAFHSGVDIAGQSGDPVYAAGAGTVLEAASSGARGNCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4986..6416
                     /gene="cls"
                     /locus_tag="PPM_RS05970"
                     /old_locus_tag="PPM_1130"
     CDS             4986..6416
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="PPM_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1130"
                     /product="cardiolipin synthase"
                     /protein_id="WP_013369851.1"
                     /transl_table=11
                     /translation="MLWLLLVLIIFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKVVRKAGSQLFREFRERLWAQTKVIENVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFEAMLTAMEQAQHHIHVEFYIFRADEIGKKFQEVMIR
                     KAREGVKVRFIVDGVGSYNLPYSFIRTCNEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGTIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDGVYFLQNVFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQELCFGALTVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGIDVKIIIPYQSDSKLVHLASLSYVQDLLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVLFATSALKRLSADFVEDISNSSKIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     misc_feature    5006..5019
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.61"
                     /tool="antismash"
     gene            6611..7555
                     /locus_tag="PPM_RS05975"
                     /old_locus_tag="PPM_1131"
     CDS             6611..7555
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="PPM_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1131"
                     /product="YitT family protein"
                     /protein_id="WP_013369852.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKVKRLLQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISDKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFIAIGNIHDVKGGRFKKKGIH"
     gene            complement(7624..8526)
                     /gene="ligD"
                     /locus_tag="PPM_RS05980"
                     /old_locus_tag="PPM_1132"
     CDS             complement(7624..8526)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="PPM_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1132"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_013369853.1"
                     /transl_table=11
                     /translation="MGRAVKGTITIEGHEIAITNPDKPLWPEAGVTKALYLRKLAVLAP
                     FLLKYCHQRLLTVIRWPHGIHGDFFYQKNAPHPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHLAGSQLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRPGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQIGDLIDKV
                     PPQPVEDLLKHMRSKTHPT"
     misc_feature    complement(8675..8688)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     misc_feature    complement(8675..8691)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.89"
                     /tool="antismash"
     gene            8733..10004
                     /locus_tag="PPM_RS05985"
                     /old_locus_tag="PPM_1133"
     CDS             8733..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /function="fOG: TPR repeat"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369854.1"
                     /locus_tag="PPM_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1133"
                     /product="sulfotransferase"
                     /protein_id="WP_014599541.1"
                     /transl_table=11
                     /translation="MCLIEKQGGKLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLL
                     SLYDLPQSHARPYGGTGILRQFFKGMVPPQVLEQASRSYALEIYNGLLEGTTADMLIDK
                     SPRYYTVLEFLDRLFPAARRVWLIRNPLAIVASFKKVNQLRGGHFHLLKELGSPHFNMK
                     MTDITVGLFRYAHYFATPHPLAYPLMYEQLVANPRMEIEKLCHFLGIHYESGMERYGNF
                     ANTPQSSLFYSMGAGDPFVMEHEQAHQNSVHSWQHLLSTLEIELYCRSIGARLFRQLGY
                     GEALEQAEQMTGVRFEDDPDVELLSRRTHQFLQQSGFEWKAAYRMLEEHDADNRVFMTN
                     ATRHAAPHNLARMDISQVVSDRRIQSLENRLAHSFEERNRLIEQLQSYQRPSQGIGSRL
                     FARKLGRWASVVLSSIGKEKGGRT"
     gene            10001..11926
                     /locus_tag="PPM_RS05990"
                     /old_locus_tag="PPM_1134"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="PPM_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1134"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_013369855.1"
                     /sec_met_domain="GATase_7 (E-value: 1.3e-19, bitscore:
                     68.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1e-25, bitscore:
                     89.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYRFGHESVYAEEGERMMQTLQKYPADRVCTWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLAVEQGRRQGITDSELI
                     LLAYDKWGVDAASFLIGDFAFVIWDATKHRLYGARDMTGNRTLYTYQYDGGFAFSTVVA
                     PLWVLSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKQLLR
                     KYACLDEVEPLRFKTGGEYIEAFREVFSQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PALHLQHKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPAMDYYA
                     RQFRRLHWLQSLQGVWRYSKLTGNRMSHLLPVMLKKATSLEARTWLRRGNRSPIPSLIH
                     PEFAKRMNVEDIPVLSGTGWRKNADQTRKEKFSNLAIANKNGVMATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRKAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQVMCHDLRAAEYLNMDYIKTAMANYRHPRPEQASDPNIRLFMHSLIVYR
                     FLCGLN"
     gene            11979..12107
                     /locus_tag="PPM_RS29155"
     CDS             11979..12107
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="PPM_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_013369856.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLYNPS"
     gene            12245..13288
                     /locus_tag="PPM_RS05995"
                     /old_locus_tag="PPM_1135"
     CDS             12245..13288
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369857.1"
                     /locus_tag="PPM_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1135"
                     /product="HPr kinase"
                     /protein_id="WP_013369857.1"
                     /transl_table=11
                     /translation="MHDRSTHIRRVKYTAFGLRIASELTLPELIPAKQGVGEDVVIRQA
                     DLSAWRDQLEQTNFVMQGERFMFLIPGTAIYAIRGGQEIEVSMLPGADPDTVRLFVLGT
                     CMGVLLLQKRILPIHGSAVAIGGRAYAFVGESGTGKSTLAAAFRQAGYQMISDDVIAIN
                     ITASAAIVYPAYPQQKLGLESLLQLEALRENRHVRQRKHVLSLTDDNPVRAQYRDLRRI
                     AGEFNKYAVPTVDEFYNDPLPLGGVFELVSDSPNRELMREGEPVAVTEQPLNKLECLHT
                     LLQHTYRRVIIPRMGLGEWYFDTAARMARKVEGWRLLRDSSFFTASEVVQRVLELIHKE
                     EKSYGSH"
     gene            13275..13577
                     /locus_tag="PPM_RS06000"
                     /old_locus_tag="PPM_1136"
     CDS             13275..13577
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369858.1"
                     /locus_tag="PPM_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1136"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_013369858.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.4e-25,
                     bitscore: 85.3, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2e-16, bitscore: 58.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATNPAKDHYRVTYGEEVYVSDMDGEKVMMSIHTGKYYNLGFTG
                     GRIWELAESSPSLGDIVTVLMNEYEVDEEQCRQQVHTFVAELEREGLLRLLRELD"
     aSDomain        13320..13556
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_PPM_RS06000_Stand_Alone_Lasso_RRE.1"
                     /evalue="3.50E-27"
                     /identifier="RREFam002.1"
                     /label="PPM_RS06000"
                     /locus_tag="PPM_RS06000"
                     /protein_end="94"
                     /protein_start="15"
                     /score="85.3"
                     /tool="antismash"
                     /translation="GEEVYVSDMDGEKVMMSIHTGKYYNLGFTGGRIWELAESSPSLGD
                     IVTVLMNEYEVDEEQCRQQVHTFVAELEREGLLR"
     gene            13579..14064
                     /locus_tag="PPM_RS06005"
                     /old_locus_tag="PPM_1137"
     CDS             13579..14064
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="PPM_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1137"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_013369859.1"
                     /sec_met_domain="PF13471 (E-value: 6.6e-24, bitscore: 82.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLPPEVRRLFPEAWLELGCARFRQRRSFGDYSGAWGKC
                     MEETPWQCEIGQEKSIRHISQAVDLASRYTPWRSSCLVQAAAAMTLLVRRKLDCTLYLG
                     TAKNAAGQLAAHAWVRSGPIYVTGEREMGAFTVVGIFGRRAGTATNTKTADKGSSLF"
     gene            14109..15635
                     /locus_tag="PPM_RS06010"
                     /old_locus_tag="PPM_1138"
     CDS             14109..15635
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="PPM_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1138"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_013369860.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.6e-85, bitscore:
                     284.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKSILELANWNEDQEFTLLLSLLRKDVNLWQDTTTAFQLQEMD
                     WSRLLRLIEHHRVVPTVYLQLKTLNHPFIPAELLRNLQAQYQRNTLRMLQLQAEAERLT
                     RLLTAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMEEAGYASKS
                     GEVRVLGSWKWKDHHASFLHLQKRVEIELHWRLHPDGGREPSFDELWDCRQMGKAAGVR
                     ASQMAPATSADNRNVMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVRAVN
                     WGALLPLMRRYGGLPAGGQAWALAAALLGTPIPEPMRPISATRQAHRLALSALAFMQAS
                     VPAPYPVANRAGTGRLVRSELLPSVALTESMNTAPLSGGISASGAAGEAVLYAVKDAAD
                     IPKDASSILSDPVNTVNTAVSSLSKPVGATTVAPSPAIAGATTTAFTPQPVSRAYLLSL
                     KEPRHRLWYLISRLFPSTRDSVVFPLPRQLHFLYIPLRPFLWLKRRFTKH"
     gene            15656..17515
                     /locus_tag="PPM_RS06015"
                     /old_locus_tag="PPM_1139"
     CDS             15656..17515
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="PPM_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1139"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013369861.1"
                     /transl_table=11
                     /translation="MTHLRIYMTKLYAVNGGALILNIGCMIIVSLLEGVGIYMLIPMLA
                     AIGVFGGHSEMPFLSDGFDYFLPYIPKSWLLPGMLMLFVVLLTGQAWLQRYQSILSSRI
                     QQRFMRCLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLVLFVVFRRSIRNAKQLGDRTTELSQAYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRIAAAVFVVSVLFVS
                     LQWLHVTPERLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQRECEAFSDPS
                     LIGLTSSKALVPFDSSVYHLPSISARQPLSLGNGIECSHLDYCYEGAAEPALRHINLFI
                     PARGMTAIVGKSGAGKSTLVDVLMGFLRPTEGQIKIDGHVLDDELLPLWRQSFGYVSQD
                     PFLFHATVRENLKLADKDASEQQLWEALHFAAADNFVSRLPEGLDTVIGDRGIRLSGGE
                     RQRLVLARAILHHPPVLILDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRH
                     ADQIVVMDQGEVIQQGNYRQLEEEERGAFSQLLSYQSSISAAP"
     gene            complement(17535..18449)
                     /locus_tag="PPM_RS06020"
                     /old_locus_tag="PPM_1140"
     CDS             complement(17535..18449)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="PPM_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1140"
                     /product="Ku protein"
                     /protein_id="WP_013369862.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVKPVVTDPGPAAKKRPTRKPAAVTAQQA
                     VAGDALSPTPVKKRRSTTKRKET"
     gene            18659..18898
                     /locus_tag="PPM_RS06025"
                     /old_locus_tag="PPM_1141"
     CDS             18659..18898
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="PPM_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1141"
                     /product="hypothetical protein"
                     /protein_id="WP_013369863.1"
                     /transl_table=11
                     /translation="MPRKPYPQQISHRVGQSHIAFRGPAGGEQDALPPEFALSHGTPPP
                     FPVAVAHVDMEAVVSTSPSHSFPSLDVERIIDED"
     misc_feature    18915..18928
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            18950..19129
                     /locus_tag="PPM_RS06030"
                     /old_locus_tag="PPM_1142"
     CDS             18950..19129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="PPM_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1142"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_013369864.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSETIAVQLDGKPIWIEHVDEANGMATVQIGSRP
                     GDTQTVRVDRLEEQ"
     gene            complement(19262..19918)
                     /locus_tag="PPM_RS06035"
                     /old_locus_tag="PPM_1143"
     CDS             complement(19262..19918)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="PPM_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1143"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_013369865.1"
                     /transl_table=11
                     /translation="MNNRELIIRRIAQEFKDGEVVNLGIGLPTMAVDYIPENVNIMLQA
                     ENGIVGVGPKAAPGKERLDCIDSGGNYVTTVKGACFIDSALSFSIIRGGHVDVTVLGAL
                     EVDEKGNLANWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKGVIDVIPGKGLMLKEIAPGLSVEDVQMATEAELMVSPHLKTIAV"
     gene            complement(19911..20579)
                     /locus_tag="PPM_RS06040"
                     /old_locus_tag="PPM_1144"
     CDS             complement(19911..20579)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426488.1"
                     /locus_tag="PPM_RS06040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1144"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_013369866.1"
                     /transl_table=11
                     /translation="MNKKVNSAEEAIKKIKDGDTVMVGGFMQGGIPEELVRALVDSNSA
                     DNLTIISNDTGTPELSIYRLVKSGRVKRIFASYIGSNPETGRLLMTKEADVQLFPQGTL
                     AEKIRAGGAGLGGILTPVGVGTIVEEGKKKIKIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNLVMATAAEYVVAQTDEYVKAGEIDPNHINVPGIFVDAIVKVGGDNE
                     "
     gene            complement(20617..21357)
                     /locus_tag="PPM_RS06045"
                     /old_locus_tag="PPM_1145"
     CDS             complement(20617..21357)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="PPM_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1145"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_013369867.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTFQGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLVVEDTETLTGTLHYNNVLVAMGTTPFKYNVLDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLENITVKGAWSGPARLSLIPHVNAPVADLPVKT
                     YVGGKHFIADLTLPYGRVLYDYLQ"
     gene            complement(21411..22595)
                     /locus_tag="PPM_RS06050"
                     /old_locus_tag="PPM_1146"
     CDS             complement(21411..22595)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="PPM_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1146"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_013369868.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4e-05, bitscore:
                     21.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVAIVSPLRTAVGSFNKTLAPLSAPELGATVMTACLQQSKLEP
                     SLIDQIFMGNVLQAGNGQNPARQAALKAGIPIDVPESTINTVCGSGLHAVALAYDSILA
                     EQGNIVLAGGMESMSNAPYLLKNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VAEKYGISRLEQDSFAYESQIKAFEAKNNKFFEEQIVPVMIKNKKETTYFTEDEHIRGN
                     TTKEKLSNLKPAFKEDGTVTAGNASGINDGAAAMLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISSLLKKQGMSIDDIDLFEINEAFAAQALAVQKELGVSPEKVNVN
                     GGAIAIGHPVGASGARVLVTLVHEMVRRSSRYGVVSLCIGTGMGIAMLVENALI"
     misc_feature    complement(22587..22600)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.1"
                     /tool="antismash"
     misc_feature    22906..22920
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 23.95"
                     /tool="antismash"
     gene            complement(23252..23782)
                     /locus_tag="PPM_RS06055"
                     /old_locus_tag="PPM_1147"
     CDS             complement(23252..23782)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429259.1"
                     /locus_tag="PPM_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1147"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_013369869.1"
                     /transl_table=11
                     /translation="MGQTVLLLIDVQQAMFMYDEKLYREQEVVAHLQQLLTEARTIGTP
                     VIFVQHTDEADEDFRENSVGWAIADVVRPLPHERIVRKSSWDSFYQTELRDVLQELGAE
                     QLIIAGMQTEFCLDTTCRSAYSLGYQNNVLVSDAHSTFDSKVLSGEQIVAHHNAVLGNR
                     FARLLTTADVHFS"
     misc_feature    complement(23805..23822)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.23"
                     /tool="antismash"
ORIGIN
        1 ttcgtaccga tccgaatggg gaagatttag ggaaggttta ccgtattacg gtcactcagc
       61 attacaagac ccgattcggt aattttgata tcgtacagcc ttgttatgtg acgcaggaag
      121 atgaggagtg gagggtgctt tggatataca aggaaaagga acagacgtga tatggtgttc
      181 ccaaaggtgt ttctgaaagg ataaatatgg tacaatactt ccaaaaccgg aaatgtacag
      241 taaaatggat gacagcttca ctccggatgg aaggagtttc atagcatgca gcaagcgaca
      301 gggcaggttc ccgtcatacg tatggagggt gtgagtaaaa tcatttcctc aaaagcgatc
      361 gtggacaatc tgacactgga ggttccggcc ggacaggtat ttggttttct cggacccaac
      421 ggtgcgggaa aaacgaccac cattcgtatg atggttggcc tgatttcgat cagcaagggt
      481 gatattcata tttgcggaga cagcatcaat accgattttg aaaaggctgt ttcccatgtc
      541 ggtgcgattg ttgagaaccc ggagatgtac aagtttttga caggctatca aaatttgcag
      601 cattttgcgc gcatgtctcc aggggtgacc caagagcgta tagatgaagc gattcgtctg
      661 gtgggactcg gaaaccgaat tcacgataaa gtcaaaacct actcgctcgg gatgcgacag
      721 cgactcggag tagctcaggc gattttgcat cgtccgaagc tgctcgtgct ggatgagccg
      781 accaatggct tggacccgca gggtattcgt gaactgcggg attatttgcg tcaattaacc
      841 cgtacggaag gaattacggt gtttgtatcg agtcatttgt tatccgaaat ggagctgatg
      901 tgcgaccgcg tggctattat tcagagcgga cggttggtcg atattaagca gttgaagaat
      961 acagagggag aagtgcagac ggcggaaatt gcttttgaag tcaatgatgc cgagcaagct
     1021 tatacgcttg ctggagcagg gcgcgtcgaa ggcaatcaac tactgcttca cctggagcgg
     1081 gaacagattg cagagatgaa cagtctgctg gctgcaaatg gagtcaaggt gtacgccatt
     1141 agcccggttg cccgtacgtt ggaagatcaa tttttggaag tgacgggagg cgggtccatt
     1201 ggctgatttc ttcaagctgg tacataatga aaatctcaaa atctacttgc gtgtgcgcac
     1261 atggatcatg ctggggctgc tggcagtcat caccgctgtg attccgatgc tgatttctct
     1321 ggtttccgat caggtcagtg tgtgggatgg catcgcattg acaacgttat ttacattttt
     1381 cctcaatacg acgtttacgg tcattgtagc tgctgattcg gtggctggtg aatttacatg
     1441 gggaacgatt aagctactgc tcattcgtcc ttggactcgc agcaaaattc tgttgtccaa
     1501 gtatatatcg gtgattttgt tcagcttgct cggaacgatc gttttggttt tgatggttac
     1561 gctgtcctcc tggctgatgt tatcgaagga tgcaccagcg ggctctgttc cgctgttcag
     1621 tgatccggta tcttacgtaa cgctgaactt tttgtatagc tatatcgccc tattcgtgac
     1681 catggctttt gcatttatgt tatctgcggt gtttcgttcg agcgccttgg cgattggttt
     1741 gtctttgttt atgatgttca ccaaaacagt gtataactcg attggtttgt tcagcacaga
     1801 tcgttttgaa tggacccaat acgtactctt tacgcatatg gatctgaaaa aatatctaga
     1861 tatgccgccg ggtacagtaa cttccgatct aaccttttcg ctcaccgtgc tggctgctta
     1921 ttatgtggtt tttatcgcaa ttgcctgggt ggttttcgta aaacgcgatg tttcaaccta
     1981 aacacgtatc tcttagaatg tgtgatttaa tcatacgagg attttggcaa aatgctaaga
     2041 tcacaaaaag gaagtccaat gcctagccat ttggacttcc ttttttgcta catattctgt
     2101 aagtgtgggt atattgtaat ctattttcag caagaatcaa tcaatagggt cggtttgcgt
     2161 ttaaagaagt agagagaaac agaacagggg gcgcatgata tgctgcaaaa taatcgtttt
     2221 tttcgtctga cttcaggaat cgtcatgcta ttgctcatca tttacttggg caccaaagta
     2281 agctttatat tcagtcctct cgtatccttg gtcagcctgc tgatagtacc gctgatgcta
     2341 tcttttttcc tctattattt attgagaccg atcgtagatg tcatggaacg aagaaaaatc
     2401 aaacgatcga tttccatatt actgatttat ttggtcattg gcgtgttact gttcctcttc
     2461 tcatggggag tatggcctac gctccgtgat caggtgacca atttatttga gaatgcgccg
     2521 aagctcatta aaagtctggt tgatcaatta agccaatggc ggcataatca atccttgaga
     2581 caagtgctgc ctccgggtga agacccgctg tcacaactgt cagatacgtt aaacgaagct
     2641 ttttcaacgc tgtcagatta ttcggtaaag ctggtatcgt tcgtatccta cttttttatc
     2701 gtattggcta cctttcccat attgctctac tacatgctga aggaaggaag caagtttggt
     2761 cctaaaatgc tcaacttctt tcctaaaaaa tatcataagg acgcgctgga agtgatggag
     2821 gatattgata gtgcactcag cagctttatc gtcagtcgag tgctgatcaa tgtcgcgttg
     2881 ggcttgatga tgttccttgg atttttgatt attggtttgc cttatgcttt gctacttgcc
     2941 gttatttcga ttttccttaa ttttattccc tatgtggggg cagtagctgc ttctatacct
     3001 gtggttatca ttggatttct cgaatcgcct tccatggcgc tctggtcgct ggtggtggtg
     3061 atcgttgcac agcaaattca ggataattgg ctgtcaccga ttgtctttgg caagcaactg
     3121 gacattcatc cgttgactgt cgtcatttta ttgctagttg gtggcgatct acttgggatc
     3181 ttgggtatca ttttggttat tccattgtat atgtgtggca aaatcgtcat acgcaaggta
     3241 taccatttat ttttggaacg cagagtggag gatattatgg agtaaatgaa ggctttgcta
     3301 gaaatataag gagtgtaagc cgccctatcc cgcttcgggt tgtagggagg cttggctgtc
     3361 ctcattgtct tggctgaaac tggattgatt ttcatcatat gatttctcta tagcagctgg
     3421 cgactctgcc tccatagttt ggttcatttg actcgtgccg ttcagtatgc cgccttcaga
     3481 aatgaccaat gtaggggtcg ccgtatttcc atatagttcg cctgtcggtg taatggtcag
     3541 ccgtccttcc gcggtgatgc tgccgaatac cttgccggca agaatgacgt cccgtgcaat
     3601 gatgtccgaa cgtacaactg ctgattctcc aatgacgaca gtacgagtgc tgtagatatc
     3661 gccctgaaaa tgaccgtcaa tgcgaatgtt ggcctctgcc tcaatcgtac cttcaaagct
     3721 agtgccgtta gcgagcagtg tatccgtcgc cggggtggag agcttttttt tggattcctt
     3781 gaacatgaac gttttcctcc aatcctttat ggtaagtatt ttgcaaaatc cttattgtac
     3841 atacagcaat ggatcgacag gttggttatg cttgacgatc tgaaaatgaa gatgaggtcc
     3901 cgtgcttctc cctgtacttc ccagcaggcc aatggtctgt cctttgtgaa cacggtcccc
     3961 gggagctacc tgcatcccgc ttaggtgcat ataccagctt tggagtccgt caggatgctg
     4021 aatgatgatg caattgccac gggctccgct ggaagcggcc tccagcacag tgcctgcccc
     4081 tgccgcatag acaggatcac cggattgacc ggcaatgtcc acgccggagt gaaaagcgga
     4141 tctacctgta aatgggtcgc tgcggtagcc gaagctggag gtcatgcgcc gcgaaccaac
     4201 aggccaaatg gagggcctcc cttgttcagc aagtgccagt ctgcgggtct ggagcagctg
     4261 tgcggcttgt tggcgctcca ggttctgctg gacggcgttt gcctgttgaa tagagcgcgg
     4321 aaccgtacgc tccacagtgt ctagcagagc ttcgatttcc tgaaaatcat ccatgacctg
     4381 gcgggctaga agagctgtat tttcatgcac tgcgatcaat tcacccccgg tatggccgga
     4441 agtatcccag gagagcggag ttatggttga tttattgctg cttgcgctgg aggaatttcc
     4501 gtgtttacga atgaattgct gcatttgttg ttccagctct gttacacgct ggagacgttc
     4561 gcgaatactg gtggcttgat tcgtcagctc catgacttcc tgccgcagtc gcccaatggc
     4621 tgcgtctttg tctgctactg tgacctccat ctgcaaactc tggacagcaa gattggtttc
     4681 catttgggaa ataatatggg aagaacggat ttgcagcccg atcacgagcg tagagattga
     4741 tgcgatcaca agggtcggga cgagaatgac agcggctgcg gagcattgta gctgcttggg
     4801 cggttgctgt gcatcccgaa tgacaagcag ggtcatccgg cgatttaggc ttcctttttt
     4861 cataatcgct cctttccgga catcgctcct atagtgcttg gttactatct attcagctta
     4921 agaggcaaac atgtcaaaaa aattggagct ttgtataaaa cgtagatata taaggaggct
     4981 tagatatgct gtggttgctg ttggttttaa ttatttttat ttttcagacc gggacgattc
     5041 tgctctttga atttcgcaag ccgtccaaag cggtagcctg gctctttatt ttgttttgct
     5101 tcccgcttat tggttttgtg gtgtactatt ttgttgcaca ggattaccag aagcgcaaag
     5161 tggttcgtaa agcaggatcg cagctatttc gtgaattccg tgaacgtctg tgggcgcaaa
     5221 ccaaggtgat tgaaaatgta gagcaaatgc acaatcccca ttttaagcat caggagcgtc
     5281 tgtttaatca gttaattcgt atgtcggaaa acccgttgac aggctgcaac cgtacacgtg
     5341 tgctgacgaa cggggaagaa acctttgagg ctatgctgac agcgatggaa caggcacaac
     5401 atcatatcca tgtggagttt tacatatttc gggcagacga aatcggaaaa aaatttcagg
     5461 aggtcatgat ccgtaaggca cgcgagggag ttaaggtacg attcattgtg gacggcgtag
     5521 ggagctacaa tttaccctat tcatttattc gtacctgtaa tgaggctggg gtcgaatttc
     5581 attattttct accgccgttt ttcgccacgc tagaccgccg gattaactat cgtaatcacc
     5641 ggaaaatcgt agtggtggac ggcacgatcg gatttgtggg gggaatcaat gtaggcgacg
     5701 attatctcgg aaagtacccc aaagtggggt tttggaggga tacgcatttg cagattgaag
     5761 gagatggcgt ctattttctg caaaatgtgt ttcttagcga ttggaagctg gcttcgggag
     5821 agaggctgat ggacgtgaat ttatttcctc cacatacctg cacaggggat gaggaagtac
     5881 agattttgag cagtggtccc gatcaggtat gggacacgat tcaggaattg tgctttggag
     5941 cgctcacggt tgccaaaaag cggatttgga taacgacgcc gtattttatt cccgatccgg
     6001 ggatttatga ggcgctgaag ctggcggccg tcagtggcat agatgtgaaa attattattc
     6061 cctaccaatc agattcaaaa ctggttcacc tggcgtcact gtcctatgta caagatttgc
     6121 ttgaggcggg agtggagttc taccaatatc gaaaaggatt tatccacgcc aaagtggtaa
     6181 ttgtggacga tttgctcggc tcggttggga ccgctaatat ggacatgcga agctttttct
     6241 ataattttga gttgaccgct gtactttttg cgacttcggc gttaaaacgg ctttcggcag
     6301 attttgtaga ggacatttcc aactcttcaa aaatagattt gaacgtgttc cgcagacgtc
     6361 ctcgatctca aaaaatagct gaaattctaa ctcgcatgct ctctcccctc ctttagaggc
     6421 ggttttcgcc gtttttatca atataatccc gctttattgt gatttatgtg ctctttgcta
     6481 acttttttgc gcaaaatcac agttttatga tatactaatc atataactaa gcgccgtaaa
     6541 ggagagggga ctgcggagag cagccccttt ttcggtctaa tataccatac tgtaacgggg
     6601 ggatttatat atgagtgtag tgagcaagga agtccaaaat ctgtctgaga tcacagatgt
     6661 aaccggagag ttgaccaaga tcagcaaaat tccagctaat ccaaagaaca aagtaaaacg
     6721 cttattacag cgtgcagcca tgatcgtggt tggtgcagcg ctgatggcag tgggattgga
     6781 aatattcctg gttcctaatg gcgttattga cggaggcgtt acaggtatct ccattatggc
     6841 ctccaagatt actggttatc cgctcggtat tttcctgacc ctgttgaacc ttccattttt
     6901 acttatcggt tacaaacaaa tcggtaaaac cttcgcttta tccacattat tcggcatcgt
     6961 cgttatgtcc atcggaactg cgttacttca caatgtaagt gcattgactc ctggggaacc
     7021 gctgcttggc gctatctttg ggggtgtcat tctcggcgtt ggggtaggtc ttgtgattcg
     7081 gtccggcggc tcgctggatg ggacagagat cgtagctatt ctcgtcagtg aaaaaactcc
     7141 tttttcggtc ggtgagatcg tactgtttgt taatattttc attctgggaa gtgcgggttt
     7201 tgtgttcggt tggccgaatg ccctgtattc catgattgct tattatattg ctatgaaaat
     7261 gattgatatt acgattgagg gtctggatca gtccaaatcg gtctggatta ttagtgataa
     7321 ataccgtgat atcggagatg ccctgacgga ccgtcttgga cggggtgtaa cttatctgga
     7381 aggtgaaggc ggctttacag gcgagagcaa gaaagtgatt ttcgtcgtca ttacccgact
     7441 ggaggaagcg aagctcaaga gcatcgttga ggattgggac ccgcacgcct tcattgcgat
     7501 tggtaatatt cacgatgtga agggcggacg ttttaagaaa aaaggaatac actagcgcaa
     7561 ggggacaatt tctcagccta tggctgcggg gttcgtcccc ttttttgtgc ttcaaagcat
     7621 ggattaggtt gggtgtgttt tggaacgcat atgcttgagg aggtcctcta caggctgggg
     7681 aggaaccttg tcgatcaagt cgcctatctg gtttaaccgt tcttcaatat tcagcaaatg
     7741 gtaatccagt ggtgacacat cctgccgtac ctcttcccag gttagtggag tggagaccgt
     7801 agcgccggga cgtgcccgtg gagtataagg agcggctaag gtttttccct gataatgctg
     7861 caaataatca aaataaatgg ctgttccgcg atccttcttt aatcgttcca gtgtgaatag
     7921 atgcgggtgc ttttccgtta caaattgtcc aaccaacagt ccgatgctgc gaagctcgtc
     7981 aaaggttatg cctggacgga tcgggacgat aatttgtaca cccgtggccc cggaggtttt
     8041 ggggacagag tccaacccaa gcgaagctaa tacttcgcct acaatggagg cagcctccat
     8101 aatgcgtggc tcgacctctc tggatggatc aagatcaatc atccattcac agggcagttg
     8161 gcttcctgct aggtgcagag agggatgaaa ttccaacgca gcttgattac cgagccagag
     8221 tagttggggc agctttccaa gcacgatata ctcaatgcca tcatgcagag cggtttcaat
     8281 gtagtctggc cgaggatgtg gggcattttt ctgataaaaa aagtccccat gaatcccatg
     8341 tggccaacgg atgacagtca gtagacgctg atggcaatat ttgagcagga agggggccaa
     8401 taccgcaagc ttgcgaagat atagcgcctt agttacacct gcttcgggcc acagcggttt
     8461 atccgggttt gtgatcgcaa tttcgtgacc ttcaatcgta atcgtacctt taacagctcg
     8521 tcccatagtg ctatgctcct ttggctaaca tgcagcaaga tcattattta cagacagctg
     8581 gctgcacttc taaatctaca taaggtttaa catgaacgtg cagcacagaa tttatccatt
     8641 aaaaggattg acaagataca ctatgtatca taaattataa taaaaatacg atgtgtatct
     8701 attaaaacgt cttgagcaga ggtagaggag gaatgtgctt gattgaaaag caaggcggaa
     8761 agctagtatt tttgttgagt gtccctcgaa gtggaagctc gctgctaacc gccattttgc
     8821 aaaaccattc ccgtctgttt gccacgcagg aaatgtggtt tctgctcagt ttatatgatc
     8881 ttcctcagtc acatgcccgg ccatatggag gaacaggaat actccggcaa ttttttaaag
     8941 gcatggtccc tccacaggta ttggagcagg cctctcgttc gtatgcactt gaaatatata
     9001 atggcctgct tgaagggacg accgctgata tgcttatcga caaatcaccg cgttactata
     9061 cagtgcttga atttttagac cgtttgttcc cggctgcccg ccgagtatgg cttatccgca
     9121 atcctttagc catcgtcgcc tcgtttaaaa aggttaatca gctccggggc ggacactttc
     9181 acctgctgaa ggaactgggg agtccgcatt ttaatatgaa aatgacagat attacggttg
     9241 gtttgttccg ttacgctcat tattttgcca cacctcatcc acttgcatac ccgctgatgt
     9301 atgaacagct cgtagccaat ccaaggatgg agatcgagaa gctgtgtcat tttctgggga
     9361 tccattatga gtcgggaatg gaaaggtacg ggaactttgc gaatacgcct caatctagtc
     9421 ttttttatag catgggagcg ggtgatccgt ttgtcatgga gcatgaacag gcgcatcaga
     9481 attcggtaca tagctggcaa catctgttga gtacattgga aattgaactg tattgcagaa
     9541 gtattggagc tcgcttgttt aggcagcttg gttacgggga ggcgctggaa caggctgagc
     9601 agatgactgg agtccgtttt gaagatgatc cggatgtaga gctgttgagt cgacgtacac
     9661 accaattcct ccaacaaagt ggctttgaat ggaaggcagc ttatcggatg ctggaagaac
     9721 atgatgcaga taacagagta ttcatgacaa atgcaacccg tcatgcagca cctcacaacc
     9781 tggcaaggat ggatatatca caggtcgtga gtgatagacg aattcaatcg ctggaaaaca
     9841 gactggcaca tagctttgaa gagcggaacc ggcttatcga gcagctccaa agctatcagc
     9901 gccctagcca aggtatcgga tcccgcctat ttgcccgtaa gctcgggcgc tgggcgtctg
     9961 tagtgttatc aagtatcgga aaagaaaaag gggggagaac gtgagtgcaa ttgccggaat
    10021 ctatagattt gggcatgagt ctgtatatgc tgaagaaggc gagagaatga tgcaaactct
    10081 gcaaaaatat cccgctgacc gcgtgtgcac ttggtgtgaa ggttccattt ttttgggatg
    10141 tcatgcccag catgtgaccc ccgaatctgt ccatgagcgt cttcccttct atgatgagct
    10201 gagagatttg gccattacgg ccgatgcgat cattgacaat cgttctgagc tgtttgaacg
    10261 gctagcagtt gagcaggggc ggcgacaagg tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggtgtag atgcagcaag ctttctgata ggtgattttg cctttgtcat
    10381 ttgggatgct acgaaacatc ggttatatgg tgctagagat atgacaggca atcgtacgct
    10441 gtacacctac caatatgacg gaggatttgc gtttagcacg gtagtcgctc cgctatgggt
    10501 tctgtcctct ctgcgaaaag aactgcatga accatggctg gccgaattct tatcgatccg
    10561 tgcaatgcag gaatccgtcg atatcggaac gaccgcctac aagcatatca atcagttgcc
    10621 tcctgcacat tggttcacca tggaagaggg aaagcaattg ctccgtaaat atgcatgtct
    10681 ggatgaggta gagccgctgc ggttcaaaac agggggcgaa tacatagaag ctttccgcga
    10741 ggtgttctca caggcggtaa ctgcccgatt acggacgcat cgcgccgtag gggctgccct
    10801 gagtggggga ttggattctg gagcggttgc cagctttgcc gcaccagcgc tgcacttaca
    10861 acacaagccg ctacatgcct acagctatgt acctgttcaa gattttacag attggacacc
    10921 gcctacatta ctggcgaacg aacgcagcta tatacagtcc acagctcgct atgtgggcaa
    10981 cattcatgaa aattatatgg attttgaggg gaaaagtccg ttttctgaaa ttgatatttg
    11041 gctggagctg atggaggctc cctacaaata ttttgagaac tccttttgga tcagaggttt
    11101 ttatgagaaa gcacaggaac ataatgtcgg tgttctgttg actggggcac gtggtaattt
    11161 taccgtatcg tggggacctg caatggatta ttacgcccgt cagtttcgtc gtttacattg
    11221 gctgcaatcc ttgcaggggg tgtggcgata cagcaagctt acgggcaatc gtatgtctca
    11281 tctactacct gtgatgttga aaaaagccac ttcacttgaa gctcgtacat ggttgcgacg
    11341 cggcaatcga agtccgattc cttcactgat tcacccggag tttgccaaac ggatgaatgt
    11401 agaagatatt cctgtattga gtggaacagg ttggaggaaa aatgccgatc agacaagaaa
    11461 agagaagttt tcgaatttgg cgattgccaa caaaaatggt gttatggcga ccaaactttc
    11521 acttcgttat ggcctgtggg aacgtgatcc gaccggggac agccgtgtaa ttcgcttttg
    11581 cttatcggtg ccttttgaac aatatgtaca aaacggtcgg gacagggccc tcattcgtaa
    11641 agctatgcgt gatcatctcc ctgatgatgt tcggttgaac cagcgggtac gcggcgtaca
    11701 gcctgctgat tggctacatc gtatgctccc ttgctgggac acgtttatgg gagaactgca
    11761 agtgatgtgt catgatttgc gagctgccga atatctcaat atggactaca ttaagacggc
    11821 tatggcgaac taccgacatc cccgtccgga gcaggcctct gatccgaata tacgactgtt
    11881 catgcacagc ttgatcgtgt accgttttct ctgtggattg aactgattct tttttatctg
    11941 gtcagacggg tgccattcgt gggaggggag gtgatgagat gagtaaaaaa gaatggcagg
    12001 aacctacgat tgaggtactg gatattaacc agactatggc gggtaaaggc tggaagcaga
    12061 ttgactgggt gtcagaccac gatgccgatt tgtataatcc tagctaatcg atcattatac
    12121 atgggccgat gctggactga gagccgaata gctttatgat cacgagccgt ctttatttct
    12181 ttgggggtag gttggaccca aagaaataaa gacgggattt taagaacagg ggagtggttc
    12241 tagcgtgcat gacaggagta cccatatccg tcgggtgaaa tacacagcct ttggactcag
    12301 gattgccagt gagctgacct taccagagtt aatcccggca aagcagggag tgggagagga
    12361 tgtggtcatt cgacaggctg atttgtcagc atggagggac caactggagc agaccaattt
    12421 tgtaatgcag ggtgaacgct ttatgttcct aataccgggc acggccattt atgccatcag
    12481 gggaggccag gaaatcgagg taagtatgtt acctggggct gatcctgaca ccgtgcggct
    12541 gtttgtactg ggcacatgca tgggtgttct actgttgcaa aaacggattt tgcctattca
    12601 cggaagtgcg gttgccatcg gaggtcgggc ctacgcattt gtaggtgaat ccggcacggg
    12661 aaaatcgacg ctggctgctg cctttagaca ggctggctat cagatgatca gtgatgacgt
    12721 gattgctata aatattacag cttccgcagc catcgtatat ccggcatatc cgcagcagaa
    12781 gctggggctg gaaagcttgc ttcaactgga ggcattacgg gagaacaggc atgtacgaca
    12841 aagaaagcac gttctttccc taactgacga caatcctgta agggcacaat accgagattt
    12901 gcgtaggatc gcaggtgagt tcaataaata tgccgtgcct actgtggacg aattttataa
    12961 cgatccgctt cccctgggcg gcgtattcga gcttgtgagc gattctccca accgtgagtt
    13021 gatgcgggaa ggggagccag tggccgttac ggaacagccc ttgaacaaac tggagtgctt
    13081 gcatacttta ctacagcata catatcgtag ggtgatcatt ccgcgaatgg gtttgggtga
    13141 atggtatttt gatacagcgg cccggatggc tcggaaagtg gaaggctggc gactgctgag
    13201 ggatagctcc ttttttacgg cgtccgaggt tgtacaacgg gtacttgaac tcattcataa
    13261 ggaggaaaag agttatggca gccactaatc cagctaagga tcattatcgc gtcacgtatg
    13321 gtgaagaggt ctatgtaagt gatatggacg gagaaaaagt gatgatgagt attcatactg
    13381 gaaagtatta taatttgggc ttcaccggag gacggatctg ggaactggca gaatccagtc
    13441 cttcacttgg agatattgta actgtcctga tgaatgaata tgaagtggac gaggaacagt
    13501 gcagacagca ggtacatacc tttgtagctg aattggagcg ggaaggattg ctgagactcc
    13561 tgcgggagtt ggactaacat gcggatacaa cggcttcttc tcttgcctcc agaggtcagg
    13621 agattgttcc cggaagcctg gctggagctg ggatgcgcga gatttcgcca gcgtcgttct
    13681 tttggagatt actcgggggc ttggggaaaa tgcatggaag aaactccctg gcagtgtgag
    13741 atcgggcagg agaagtctat ccgtcacatt tcacaagctg tggatttggc cagccgttat
    13801 actccttggc gcagtagctg tcttgtacaa gccgctgccg ctatgacgtt gctggtacgc
    13861 agaaaactgg actgcacact gtatctgggc acagccaaaa atgctgcggg acaactggcc
    13921 gcacatgcat gggtacgcag tgggccgatc tatgttacgg gagaacggga gatgggggcg
    13981 tttaccgtag tgggaatatt cgggagacgt gctgggacag ctacaaatac gaagacagcg
    14041 gataaaggca gttctttgtt ttagtgtgag aaaaaaagag tgttcaaaga atcgaaggag
    14101 aagaatccat gactaccaag tctattttgg aacttgcgaa ttggaatgag gatcaagaat
    14161 tcacgttatt actctctcta cttcgtaaag acgtcaatct atggcaggat acgacgactg
    14221 ctttccagct gcaggagatg gattggtccc gcttgctgcg tctgatagaa caccatcgtg
    14281 tggtacctac agtgtatctc cagctgaaaa cgttgaatca cccgttcatc cccgcagaat
    14341 tgctgcgaaa ccttcaggca caatatcaac gaaacacgct acgcatgctc cagcttcaag
    14401 cagaagccga gcgtctgacc aggctgctca cagctcatgg aatccgtgtg ctgatgctga
    14461 agggtcctgc tctggcgcag caattatacg gggatgtttc cctgcgtacc tctaaagaca
    14521 ttgatttact tattgccccg gatgacatgg atgaagcgga gcattggatg gaggaagccg
    14581 gatatgcgtc caaaagcgga gaagtacgcg tccttggtag ctggaagtgg aaggatcatc
    14641 atgcctcctt cctacatctg caaaagaggg tagaaatcga gttgcactgg cggcttcatc
    14701 cggatggagg gcgggagccc tcctttgacg agctttggga ctgtcggcaa atggggaagg
    14761 ccgcaggagt tcgagccagt cagatggcac cggcgacttc tgccgacaac aggaatgtga
    14821 tgacatcctg tatgtatacg cttggcagcg agcatcaatt tctatacttg agcgcacacg
    14881 gagcgcgtca cggctggttc aggctgcgct ggttagtaga catcgacagg cttgcggtac
    14941 gcgctgtcaa ttggggggcg ctactgccgc taatgcgccg ttacgggggc ctgcctgcgg
    15001 gcgggcaggc ttgggcgctg gccgctgcgc tgttgggtac gccgatcccg gagccgatgc
    15061 gtccgatatc ggctacccgg caggcgcaca ggcttgcgct gagcgcgctg gcctttatgc
    15121 aggccagcgt ccccgcgccg tacccggttg ccaatcgggc gggtacaggc agactcgttc
    15181 ggtcagagct gttgcccagc gtagctttga ccgagtcgat gaataccgcc cctttgagtg
    15241 gcggtatttc agccagtgga gccgcaggcg aagctgttct gtacgccgtc aaggatgctg
    15301 ctgacatacc gaaagatgcc agcagtatcc ttagtgaccc ggtgaataca gtgaacactg
    15361 ctgtaagcag cctttccaag cctgtaggtg ctactacagt cgcccccagt ccagccattg
    15421 ctggagctac aacaacagcg tttacccctc agccggttag tcgcgcttac ttgctttcct
    15481 taaaggagcc aaggcacaga ctatggtatc tcatcagccg tttgtttcct tctacgaggg
    15541 attcagtcgt ttttccactg cctcgccagc tgcatttttt gtatattcct ttacgtccat
    15601 ttctttggct gaagcggcga tttacaaagc actgacccga taaggagtgt acattatgac
    15661 tcacctgcga atatatatga ccaagctgta tgctgtgaac ggcggggcgt taattcttaa
    15721 tattggatgt atgatcatcg tcagcttact ggaaggtgtc ggcatttata tgcttattcc
    15781 tatgctggcg gccatcggtg tatttggtgg tcattcagaa atgccatttc tgtcggatgg
    15841 atttgattat tttttgccgt acattcctaa aagctggctg ttgccgggga tgttaatgct
    15901 tttcgtagtg ctgcttacag ggcaggcttg gcttcagcgt taccagtcca ttctcagctc
    15961 gcggattcag cagcgtttta tgcgttgcct tcgcatagac gtatacactt cctttatgaa
    16021 ggcgcagtgg gctttttatt tgcgtcagcg taaatctgat tttagccatg tgatgacgac
    16081 cgagctggcg cgtgtcagtc agggaacgaa tttgctcctc caactgacca cagccgtcat
    16141 gtttacgcta atccagattg cgctggcttt ttggttgtcc ccttctttaa ccgggctggt
    16201 gtttttgagt ggactggtgt tgtttgtcgt gttccgtcgc tccatccgaa atgccaaaca
    16261 attaggtgat cgtaccactg aactgtcaca ggcttatttt gccggaatta cggatcatat
    16321 gaacgggatg aaagatatta aaagcaatct gctggaagcg gcgaatatcc attggtttcg
    16381 atctctgaca cagcgtatgg aggataatac gactcagttt gttcgacaaa atgcgaccac
    16441 gcagtttttt catcgcatag cggcagctgt ttttgtcgtt agtgtcctat ttgtgtcgct
    16501 ccagtggctg catgttacac ctgaaagatt gattgtgctc atccttatat tttcccgctt
    16561 atggccaagg tttgccctta ttcaagcgag cctggaatac atcatgtcta tgatctctgc
    16621 ttttgagagt gtaaccaaag tgcaacgaga atgcgaggct ttctcagacc cctcgttgat
    16681 cgggcttaca tcttctaagg ctcttgtccc attcgattca tcggtatatc atctaccatc
    16741 tatatctgca cggcaacccc tatcccttgg taatggaata gaatgcagcc atttggatta
    16801 ttgttacgag ggtgcggcag aacctgcact acgtcatatt aatttgttca tacccgcccg
    16861 gggaatgacc gccattgtag gcaaatcagg agcaggcaaa agcaccttgg ttgatgtcct
    16921 gatgggtttt ttacgcccaa ctgagggaca gattaaaatc gatggtcatg tgctggatga
    16981 cgaattgctg ccgctgtggc ggcagtcgtt tggttacgtg tcacaggacc catttctgtt
    17041 ccatgcgacc gtccgcgaaa atttgaagct ggctgataag gatgccagtg aacagcagct
    17101 atgggaggcg ctacattttg cagccgcaga caactttgta tccagactgc ctgaagggct
    17161 ggacacggtc attggtgatc gcgggatccg tctgtccggg ggagagcgtc aacggctggt
    17221 attagcgcgg gccattttgc atcatcctcc tgtacttatt ttggatgaag cgacaagtgc
    17281 gctggatggt gagcatgagg ctgcaattca ggcagcattg gaacggatga aaggtcaaat
    17341 gacgttgatc gtgatcgctc accgtctgtc aacgatcaga catgcggatc aaattgttgt
    17401 aatggatcaa ggtgaggtca tacagcaggg gaactaccgc caattggaag aagaggagcg
    17461 gggggcgttt agtcagctac tatcgtatca aagcagtatc agcgccgccc cttaatcaga
    17521 cttttctgta aagctcaagt ttctttacgt ttggtggtgc ttcttctctt tttgactgga
    17581 gtcggagaga gggcgtcgcc tgccacagcc tgctgtgctg tcacggctgc tggtttacgc
    17641 gtaggacgtt ttttcgcagc aggaccagga tcggtaacga caggcttcac tgcctcaata
    17701 ctggcttgaa gggcagccat taagtcaacc acattggtct gaggctgtgt tggggcaatt
    17761 cgcacctctt caccagccac tttatgctgg ataagatcca gcagacgttc gcgatactga
    17821 tccgtatact ttgctgcatc aaaaggggta gatagctgct caatcagcat ttttgccatg
    17881 gtcagctctt tctctttaac ctcctcctgt ccaggtaagt tgggaacttg agcaatggga
    17941 cggatttcgt ccggataaaa catggtctcc accgccaagc attcatccag cacgcgaatg
    18001 gctgccagac tactttttga gcggatggag atttgggcaa tcccgatttt cccggtatct
    18061 ttcattgcat tcatgagtag cttatacgca ttcgagccag cctgatccgg ggacaaataa
    18121 tacgtttttt gaaagtagat cggatcaatt tcctgtaaat ccacaaagtc caaaattacg
    18181 atatttttat cggcttgtcc gctaacttgc tccagttctt ccttgtcgaa catgacaaat
    18241 tttccttttt catattcgta cccttttcca atttcctccc attcaacctc cttatcacaa
    18301 acagggcact tccgtacata gcttagtgga ctcccacact ccttgtgaat ataacgcatg
    18361 gaaatgtcct tgtcctcagt tgctgagaac attttaactg gcacatgaac cagcccgaag
    18421 ctgatcgcgc ctttccagac cgtatgcata ccgccagtcc tccttttttt aatccgcata
    18481 tttcatattt cgattccggg cacccgggct gtgagcattt catttttcac ttagtatgct
    18541 tcgtacaaaa gattgtatga gatgcaaatg aaggctcgaa ttgctttcac ttgcgcatgg
    18601 tttcggtttt tttggtgaat gttaagccat atccgattca aaaggaggta tacaactgat
    18661 gcctagaaaa ccctatcctc agcagatcag tcatcgtgtg gggcaaagtc acattgcctt
    18721 tcgagggcct gctggaggcg aacaggatgc attgccgccc gagtttgctc tttcacatgg
    18781 aacgccgccg ccttttcccg tagctgttgc tcatgtggat atggaggctg tagtttcaac
    18841 atcgccttct catagctttc cttcattgga tgtggaacgg attatagacg aagactaggt
    18901 gacctatatt ttgaattttg cacaaaaaaa agagtaggag gagaacagca tgaacgtgga
    18961 acgagcaaaa gccatttatg attcatccga aacgattgcc gtccaattgg atggcaaacc
    19021 gatttggatt gagcatgtag atgaagcgaa tggtatggca acggtacaga tcggcagcag
    19081 accgggtgat acacaaaccg ttcgtgtaga tcgattggaa gaacaataga agagaggctc
    19141 caacctaaaa aggctcgcaa ttgctcaatg agcaattagc gaaccttatt ttatataatg
    19201 aatgcgattg tgaagacaag ttaaacgcca gacaagttaa tttgaaggtg gaactgattt
    19261 tttacactgc aatggtcttt aaatgtggag aaaccatcaa ctcagcctct gtcgccattt
    19321 gaacatcttc caccgacaaa cctggagcaa tttccttgag catcagccct ttacccggta
    19381 taacatcaat gacacctttt tcggttacaa tggtctttac cacatttaca gcggttaggg
    19441 gcagcttgca ttgtttcagt attttcggcg ccccattttt gttcacatgc tccatggcta
    19501 caatcactct cttggctcca accaccaaat ccatggcccc acccatgcct ggcacctttt
    19561 tcccggggat catccagttt gcaaggttgc ctttttcatc gacctccagg gcacccaaaa
    19621 cggtgacgtc cacatgccct ccacgtatga tggaaaatga aagcgcactg tcaataaagc
    19681 aggctccttt cacggttgta acgtagtttc cgcctgaatc gatacaatcg agtctttctt
    19741 ttcccggagc tgctttgggg ccaacgccga cgattccgtt ctccgcctgc agcataatat
    19801 taacgttttc ggggatgtag tccaccgcca ttgtaggcaa tccaatacca agattaacca
    19861 cttcaccatc tttgaattct tgggctattc ttctaataat caattctcta ttattcatta
    19921 tctccaccca cctttacaat cgcgtcgaca aatattccgg gaacgttgat atgattgggg
    19981 tcgatttccc ccgctttcac gtattcgtct gtctgagcaa ctacatactc ggctgcggta
    20041 gccatcacca aattgaagtt gcgtgaagag ccgttgatga caaggttccc tgcttcatca
    20101 gctttatggg ctctgataag cgccacatcg gctttgagcg gtagttcgag cagatattct
    20161 ctttcgtcaa ttttgatttt cttttttcct tcctctacaa tggtgcctac acctacgggg
    20221 gttaaaatac cacccaaacc agctccgcct gcgcgtattt tttcagcgag cgtcccttgc
    20281 gggaagagtt gaacatccgc ttctttcgtc atcaggagtc ttcccgtttc cggattggag
    20341 ccgatatagg atgcaaaaat ccgcttgact ctgccacttt tcacaagtct ataaatagat
    20401 aattccggtg tgcctgtgtc attggaaatg atcgtaagat tatcagcgga atttgagtcg
    20461 acaagcgcac gcaccagctc ctccggaatg cctccttgca taaaaccccc aaccatcacc
    20521 gtgtctccgt ctttaatttt cttaattgct tcttcagcgg agtttacttt tttattcatg
    20581 gttccgtctc cttatctatt tttaggaaag caaactttat tggagataat cgtataggac
    20641 tcttccatat ggaagcgtta aatcggcaat aaaatgtttt ccgccaacat aagttttaac
    20701 cggcaaatct gccacaggag cattgacatg ggggatcaag cttaatctag caggccctga
    20761 ccaggctcct tttacagtaa tattttcaag attatatgcc actagctgag caattttagg
    20821 agtgccgtcc acatcaggaa ttaattttaa attaacttgc gtttttgcga tggctttagc
    20881 cgtttccttt tcatcaagca cgttatattt gaaaggggtg gttcccatag ctaccaggac
    20941 gttattgtaa tgcaatgtac ccgtcagcgt ctctgtatcc tcaacgacca ggcgaggctt
    21001 cgcccatttt ttcggaaatc cccagatttc acgtcccccc agaatagcag gtgcattatc
    21061 caaatacatt tgggcaacaa aattacacgg ttctccctga aaagtacacg gaatgacaat
    21121 accgctttcc tcatagcttc ccaaaccgga tgaatcgggc attttgatcc attcatagga
    21181 gaccgtatta cttccatctg gctgaagtgg ttccgggacc gcctgtctta tcgcagcggg
    21241 atcggattca taggtaataa tgaagaattc ccggttgatg aagcggcatg gcgggcgtcc
    21301 ataactgccg ctggccgcag gcatggattg aagtgaaagt acatcttttt gattcatagc
    21361 gatctccctt cctttttaag aggtatttca acaatcattg aaaacgaact ttaaatgagt
    21421 gcattttcaa ccagcattgc tattcccatt cccgttccga tgcataacga gactacgccg
    21481 taacgtgaag atctgcgcac catttcatga actaacgtaa ccaataccct agcaccgctt
    21541 gcaccaacag gatgaccgat tgcgatcgcg ccgccattga cattgacctt ttccggactg
    21601 actcccagct ctttttgcac cgctagtgct tgtgcagcga acgcttcatt aatttcaaag
    21661 agatcaatgt catcaatcga cattccctgt ttcttcagca gtgacgaaat ggcttttacc
    21721 ggtcccattc ccatatatgc agggtcaaca ccaacaagcg aataaccctt gatatatgcc
    21781 aacggcttta acgcatgttc cttacattta tcttccgaca cgactaacat agctgccgca
    21841 ccatcattga ttcccgaagc atttccggca gtaaccgttc cgtcctcttt aaacgcaggc
    21901 ttcaagtttg aaagtttttc tttcgtcgta tttcctctta tgtgttcgtc ttctgtgaaa
    21961 taagtagttt cttttttgtt tttgatcatg accggaacaa tttgctcttc aaaaaacttg
    22021 ttgttttttg cttcgaaagc ctttatctgg ctttcatagg cgaatgaatc ttgctccagt
    22081 cttgagattc catatttttc ggcaacattt tcggcagtaa ttcccatatg gtaatggttg
    22141 attgggcatg ttaggccgtc agccaccagg gagtctacca attcaccgtt gccaagctta
    22201 tagccgtttc ttgcattttt tagcagataa ggggcgttcg acatgctctc catgcctcca
    22261 gccaagacga tgtttccttg ctccgccaat attgaatcgt aagctaacgc gacggcatga
    22321 agtcctgaac cgcaaaccgt gtttatcgtt gattcgggta catcaatggg gatacccgct
    22381 tttagtgccg cctgtctggc aggattttga ccattgcccg cttgaagaac atttcccata
    22441 aaaatttgat caatcaaaga aggctccaat ttactttgct gcaggcatgc tgtcatcacg
    22501 gttgctccca attcaggagc gcttagaggc gcaagggttt tgttaaaaga accgaccgct
    22561 gttctcaacg ggcttactat agctactttt ttcataaaaa ctcacattcc tttcgctgtg
    22621 ttcgagacac aatacatcca tgactgcact tcaattcata ctttccggtc ctaacctacg
    22681 aaacgtagaa actgcaagat acatttacat gcgggcatat catggtgcct aagacagtga
    22741 gtgtgacggt ccgatcgcct tctttcgttg ctggaaatta aaaccagaat tatcatagtt
    22801 ctaatacaga ttttgctcaa tgttcaaatc tttacatata tccaaatata gagccatatc
    22861 ttccacaata aataggccat cctaatgttt tctgttaatt tcttgatctt tctgaaaatt
    22921 gtgatcaaaa attgaatttt atgttaaata tgaaatttca aatcaacctg tgaaaataat
    22981 ttcttagcaa atcatttaga tcatcgcagg ggaggaaatc cctttatatg taaatttgta
    23041 actgacttat agcatctaaa aaagctaggc aagttgccaa tcaaaatgaa tacatttgga
    23101 attcggataa acataaatcc atataagcct gagccaccta tagcattgac gttataacgt
    23161 cagtgttttt tatttgctcg cgtgaacaaa aaaagaagcc gacctgcttg aaagcaatcg
    23221 gcttggaacg taaaaaattc acttctacat ttcacgaaaa atgtacatct gccgttgtga
    23281 gcaaacgtgc aaaacgatta cctagcacgg cattgtgatg agctacgatt tgttcgccgc
    23341 ttagtacctt gctatcaaat gtactatgcg catccgatac gagcacgttg ttctggtatc
    23401 ccagactata ggcgcttcgg caagtcgtgt cgagacaaaa ttcagtctgc atcccggcaa
    23461 taatcagctg ttccgccccc aattcctgga gcacatcacg caattcagtt tggtagaagc
    23521 tgtcccagga tgattttcgg acaattcgtt catgaggaag aggacgcacc acgtcggcga
    23581 tggcccagcc tacactgttt tcccggaaat cctcatccgc ttcatcggta tgctgcacga
    23641 aaattactgg tgtgccgata gttctggctt cggtcaaaag ctgctgtaaa tgcgctacaa
    23701 cttcctgctc acgatacagc ttctcatcat acatgaacat tgcctgctga acatcaatca
    23761 agagtaaaac ggtttgtccc atcagtttga ttccctcctt gtgtgtaaca cttaacttac
    23821 aatagcatgt cttcatgcct tgcggcgaca taaggtgaac tatataataa agaacaagtt
    23881 ggaacggtcc gattcggacg aaaggtgatt aaaagatatg acaatttcgc aggaacagtt
    23941 tgtattccgt tctgtctcag aggcacagac cgggacatta gcaggctttt tggcagccca
    24001 agcggttccc ggaaccgtga ttgtgctgga cggagatctg ggagcgggca agactgcttt
    24061 ttcc
//
