LOCUS       NC_017542              20237 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Paenibacillus polymyxa M1, complete sequence.
ACCESSION   NC_017542
VERSION     NC_017542.1
KEYWORDS    RefSeq; complete genome; complete replicon.
SOURCE      Paenibacillus polymyxa M1
  ORGANISM  Paenibacillus polymyxa M1
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Niu,B., Rueckert,C., Blom,J., Wang,Q. and Borriss,R.
  TITLE     The genome of the plant growth-promoting rhizobacterium
            Paenibacillus polymyxa M-1 contains nine sites dedicated to
            nonribosomal synthesis of lipopeptides and polyketides
  JOURNAL   J Bacteriol 193 (20), 5862-5863 (2011)
   PUBMED   21952539
REFERENCE   2  (bases 1 to 5864546)
  AUTHORS   Blom,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2011) Cebitec, Bielefeld University,
            Universitaetsstr. 25, D-33615, GERMANY
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 01:49:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,687
            CDSs (total)                      :: 5,531
            Genes (coding)                    :: 5,427
            CDSs (with protein)               :: 5,427
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 45 of 104
            Pseudo Genes (incomplete)         :: 71 of 104
            Pseudo Genes (internal stop)      :: 16 of 104
            Pseudo Genes (multiple problems)  :: 23 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:14:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1242604
            Orig. end                         :: 1262841
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            HE577054.1.
            Accession number for plasmid pPPM1a in this genome project:
            HE577055.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20237
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="proteusin"
                     /region_number="4"
                     /rules="(PoyD or TIGR03793)"
                     /tool="antismash"
     cand_cluster    1..20237
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PoyD or TIGR03793)"
                     /kind="single"
                     /product="proteusin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20237
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10237](-)"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10237)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PoyD or TIGR03793)"
                     /neighbourhood="10000"
                     /product="proteusin"
                     /protocluster_number="1"
     gene            complement(316..993)
                     /locus_tag="PPM_RS05325"
                     /old_locus_tag="PPM_1005"
     CDS             complement(316..993)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309053.1"
                     /locus_tag="PPM_RS05325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1005"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_013369710.1"
                     /transl_table=11
                     /translation="MNRKSIRPWYTLCLLAIMLVLVAGCGTKAADVEAASRTSTTTPAA
                     TKDKSKTVSHPVVTIVMNDGKKIKLELYPEVAPNTVNNFISLVQKGAYNGTIFHRVIPG
                     FMIQGGDPQGNGTGGPGYSIKGEFKSNGVNNTLKHTRGVLSMARSADLDSAGSQFFIMV
                     ADADYLDGQYAAFGKVTSGMDVVDAIVNSKRDSNDKPTKPATMKKVTVDTLGKKYPEPV
                     KVK"
     gene            complement(1324..1581)
                     /locus_tag="PPM_RS05330"
     CDS             complement(1324..1581)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821374.1"
                     /locus_tag="PPM_RS05330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YqkE family protein"
                     /protein_id="WP_013369713.1"
                     /transl_table=11
                     /translation="MAKKRNSSFAAPAAQDKPATLKDLLSQDVLNKLKAQANEAQAEQD
                     KRKEDERQRALEAKKAEQKKLDNNFEHLLNNSDLDWHKYK"
     gene            1713..2945
                     /locus_tag="PPM_RS05335"
                     /old_locus_tag="PPM_1006"
     CDS             1713..2945
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686325.1"
                     /locus_tag="PPM_RS05335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1006"
                     /product="MFS transporter"
                     /protein_id="WP_013369714.1"
                     /transl_table=11
                     /translation="MHLYWKRNLIVLWIGVLFCSMAYSVSIPFLPIFLNTELGVNDHLE
                     LWSGIAFGVTFLASALIAPFWGSLADKYGRKPMLIRSGFSLAVLYLVCALVTDPYVFVG
                     VRLFQGLLSGFIPAAIALVGTGSPEEKTGYALGIMATAGATGSIIGPLIGGVVSHYYGN
                     RNAFYFSAALVLVSAFIATFGAREDSFKGTSTRSHVRDDIKEAIANRPLYFLLILAGLS
                     TFSVMILEPLITVYVLEMGVDRSHASLSSGIVFSAVGIAAVLMAPRWGRIGGKIGFAQV
                     LLIGLIGSGIGNILQFFVTNFVGFGALRFGYGLFYASVMPAINAMTVEVTKPEFRGRAF
                     SLNQSATQLATMAGPLIGGMLGSWMPIRWIFVLNSGILLVAALLLWAKGKNVFPISAQN
                     NATDQNIHSAG"
     gene            3033..3212
                     /locus_tag="PPM_RS05340"
     CDS             3033..3212
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369715.1"
                     /locus_tag="PPM_RS05340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_013369715.1"
                     /transl_table=11
                     /translation="MIRDDILRQQLENARQKLYILQAKHGFNHASVLKQSVIMDNLINQ
                     YNHLFYIKEKKPTA"
     misc_feature    3063..3081
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.78"
                     /tool="antismash"
     gene            complement(3280..4182)
                     /locus_tag="PPM_RS05345"
                     /old_locus_tag="PPM_1007"
     CDS             complement(3280..4182)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686326.1"
                     /locus_tag="PPM_RS05345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1007"
                     /product="EamA family transporter"
                     /protein_id="WP_013369716.1"
                     /transl_table=11
                     /translation="MNKVIAHHSESNRIYYTSTILALLIWSTSFIATKAAYTTFPPLTL
                     GLSRFIIASIVLGIVLLIKKEHVKVKPKDLATISFSGVLGITLYFSMENIGVSLTTASN
                     AALIVASYPAITSLLEFILYKVKLSKYKICGIALAMIGVYFLTSVGESSDGKNQLIGNL
                     ILIGTGFAWAFYTFMTRKVVDKYPPVTLSFYQTVAGSIFFIPLALLEKDSWQAPTTGSF
                     MLLMYLGVFCSVIAFLLYNYGLIKLSPSSSVSLMNLVPIFGVLFSVLLLHETITWRQII
                     GGLVVILGVLMSAHQTSRT"
     gene            4338..5198
                     /locus_tag="PPM_RS05350"
                     /old_locus_tag="PPM_1008"
     CDS             4338..5198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369717.1"
                     /locus_tag="PPM_RS05350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1008"
                     /product="TrmB family transcriptional regulator"
                     /protein_id="WP_013369717.1"
                     /transl_table=11
                     /translation="MKSKPNILEILRDLNFSEYEAKAYVTLLESSPLSGYAVSLNSGVP
                     RSKIYEVLSGMVNRGDIMVSQENTPLYVPLPPHELIAQRKRKAEQIFNVAQESLEQYTA
                     SFQNRENIWNISGYEAIINRINEGVKGAKHRILLEIWKEDAEVFRDALEQAAQQGIEVI
                     LVAYGDLNFDFATVYRHDMSEEITSEIGGRWIVLSVDDREVVAGILSLGDDSRAAWTLH
                     PGLVMPITEVIIHDIYIMEILYEFREELEAKFGPNLIHLRNKFAMGPNGKGYYVPLTEK
                     SIKRV"
     gene            complement(5338..6420)
                     /locus_tag="PPM_RS05355"
                     /old_locus_tag="PPM_1009"
     CDS             complement(5338..6420)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046417 - chorismate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369718.1"
                     /locus_tag="PPM_RS05355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1009"
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="WP_013369718.1"
                     /transl_table=11
                     /translation="MSTNENSLELLREQLDATNLQLLELLSQRAELAGQLGKLKEAQGV
                     PDFDPVREQQMLDKLIAANRGPFDDATIRQLFKNIFKASLNYQKEEHKKHLIVSRKNQP
                     DSTVIKVKDTLVGGKASIMVAGPCSVESYQQTREVGAALKEAGVPILRGGAFKPRTSPY
                     DFQGLGIEGLQILKRVGDEFGLATISEIVDPRHLEEAIPYIDIIQIGARNMHNFELLKA
                     AGETRTPVLLKRGLAATMEEFLHAAEYIVSRGNTQVMLIERGIRTYEKWTRNTLDISAV
                     PILKKESHLPVLVDVTHSTGRKDILAPCAKAALAAGADGIMVEVHPNPAVALSDAQQQL
                     NIPEFHNFLSEVKESGLFKA"
     misc_binding    complement(6504..6777)
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     gene            complement(7149..7409)
                     /locus_tag="PPM_RS05365"
     CDS             complement(7149..7409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369720.1"
                     /locus_tag="PPM_RS05365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_013369720.1"
                     /transl_table=11
                     /translation="MANRDNQKTELQDHDFEPSLQNAETNWENLIEGPDTPLEDVPDAD
                     ELTPNSPVDPSAPAEFLHGTDLLNGTDGDEEEQLDSDDILD"
     gene            7593..7880
                     /locus_tag="PPM_RS05370"
                     /old_locus_tag="PPM_1010"
     CDS             7593..7880
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369721.1"
                     /locus_tag="PPM_RS05370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1010"
                     /product="hypothetical protein"
                     /protein_id="WP_013369721.1"
                     /transl_table=11
                     /translation="MEWYMFGPMISRIRVGQKASTPGYSRTVIRRPDGLYWTDGGQAGK
                     IVEIRDYLFSDIWTIYEDEECEPWIGLREQMEQREQEMIINQYEDFTNND"
     gene            8012..9901
                     /locus_tag="PPM_RS05375"
                     /old_locus_tag="PPM_1011"
     CDS             8012..9901
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686330.1"
                     /locus_tag="PPM_RS05375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1011"
                     /product="ATP-binding protein"
                     /protein_id="WP_013369722.1"
                     /transl_table=11
                     /translation="MRHVPKAVAALLAVIVILLSLDHIGYAAKMTPEREYKIPSWDMRW
                     GAEDEDGSLDEVTDHSKVWMHIEDDTQLLKQPGNRGTAWIRIKLPSLNDETPAVLFENI
                     YGRHITLYKDGTNFYESYRGYNYENNRILIPLKPEDSGKTLYIWTESSKNRLGIIGNVM
                     TGDYRDLLGNLVRMDVLDIVLGSTFIFIALVLLICSFFLFRPSMAMWLSLSAIVLSIGL
                     MIVTYSPFLYTFYRGYGKLYLQLFDVALFILLPSLAFFFEQNINSILLIRKFRKLLTAY
                     SLFCFIIMIVNLGAQERLNDVYYFFSVIVLGILLVALMVLLVFASIRMALKGDHEAIIL
                     STGFAFFAVITIAELSWFFIRDGHYNMFLWKWGVFGFVLALIAILGRRLAEKHKQVVRY
                     SRELEMFNNELQRSEKMEIISDLAASVAHEVRNPLQVTRGFLQLMSKQEDGKNKDYLHI
                     ALEELDRASAIITDFLTFAKPEFDHTKTLTILDEFKHIEGIISPMANLQGGKISLDIPQ
                     EIKVRGNSSKFKQAFINIIKNSIEALREQGHIHIWAYVDNGEAVIHIRDNGEGMDAQTL
                     SRLGEPYFSNKTKGTGLGMMVTFRIIETMNGKISFTSAKGVGTEATIRFPVAG"
     gene            complement(10001..10237)
                     /locus_tag="PPM_RS05380"
     CDS             complement(10001..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     proteusin: TIGR03793"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429107.1"
                     /locus_tag="PPM_RS05380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NHLP leader peptide family RiPP precursor"
                     /protein_id="WP_013369723.1"
                     /sec_met_domain="TIGR03793 (E-value: 1.1e-19, bitscore:
                     68.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATEVLQTQVIQKAWEDASFREKLMADPKSAIRDVLGVVIPDHIQ
                     IKTVEETSDQFYLVIPPNPSGVLATSQKPRAMW"
     gene            complement(10313..11248)
                     /locus_tag="PPM_RS05385"
                     /old_locus_tag="PPM_1012"
     CDS             complement(10313..11248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369724.1"
                     /locus_tag="PPM_RS05385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1012"
                     /product="hypothetical protein"
                     /protein_id="WP_013369724.1"
                     /transl_table=11
                     /translation="MEWYFAYKEELEKVFRQAEERTATFPVPFQQEGLDYLARFNPLRE
                     DSTRNYICYLLPFWLQELTGLSPETCRKLSLGNVFVMAHYLIQDDVMDTAADNRKTQLA
                     LSQLFYTECLNIYQELFPATSPFWSYARTYVDEWAVSVISEGTEDYFQGERNKVALKAS
                     PLKMAGTGALLLADHADLIQTVTHMTDLSLLVLQMSDDWADWSEDLVEHSYNCLLSHIS
                     AEQKTAYCEGLGPQQIQEAIYVRGALASYANIANQSVQELETMEPSIHGLYRFAHSIAT
                     ELSEEAAEIEGGRSHLRRGGLDYWLSKNMK"
     misc_feature    complement(11344..11358)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.42"
                     /tool="antismash"
     misc_feature    complement(11363..11378)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.74"
                     /tool="antismash"
     misc_feature    11365..11376
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.03"
                     /tool="antismash"
     misc_feature    11414..11423
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(11414..11427)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.67"
                     /tool="antismash"
     gene            complement(11427..12500)
                     /locus_tag="PPM_RS05390"
                     /old_locus_tag="PPM_1013"
     CDS             complement(11427..12500)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369725.1"
                     /locus_tag="PPM_RS05390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1013"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_013369725.1"
                     /transl_table=11
                     /translation="MSIAKLGKWTAIMSITVSLFTGSLVISNNQAHAADCSNGYVALTF
                     DDGPNPSNTRALLSALKQNGLRATLFNLGQNAQNNSSLVREQQAAGMWIGNHSWSHPHM
                     TQLSASQMSSEITRTQQTIQSITGTAPKLFRPPYGETNGTLKSIENQNGLTEVLWNVDS
                     QDWNGASTAQIVAAASRLKNGDVILMHDQYQTTLQAIPQIAQNLKNRNLCSGMISPSNG
                     RAVAPDGKNNETPPNTSTKIEAVNMTKSGQYTSNISSPFNGVALYTNNDSVKFTQNFTS
                     GTHSFSLRGASNNSNMAKVDLKIGGQTKGTFYFGGSSPAVYTLKNVNHGTGNQKIELVV
                     TADDGTWDAYLDYLEII"
     gene            complement(<12619..>12738)
                     /locus_tag="PPM_RS29875"
                     /old_locus_tag="PPM_1014"
                     /pseudo=""
     CDS             complement(<12619..12738)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008346560.1"
                     /locus_tag="PPM_RS29875"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="PPM_1014"
                     /product="1,4-beta-xylanase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MALFRKGKKFDETKTHQQIGNISVNYSANYQPNGNSYLCV"
     gene            13072..13548
                     /locus_tag="PPM_RS05395"
                     /old_locus_tag="PPM_1015"
     CDS             13072..13548
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369726.1"
                     /locus_tag="PPM_RS05395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1015"
                     /product="hypothetical protein"
                     /protein_id="WP_013369726.1"
                     /transl_table=11
                     /translation="MKKQWKLTAAILYGGVMMFGATSAAGAYSMESEHSLQALTPNNSV
                     QGEAQQWNVEPQDDDGHGHVHRHRHGKRPGGLNHHLNEKVARLLGITPVQLEKELGQGK
                     SLAEVAKSKGIQEDQLIDKLKNEMTVDLKRLVNRKGPITFDRKSGTSNEAQLKQ"
     gene            complement(13599..14093)
                     /locus_tag="PPM_RS05400"
                     /old_locus_tag="PPM_1016"
     CDS             complement(13599..14093)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369727.1"
                     /locus_tag="PPM_RS05400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1016"
                     /product="hypothetical protein"
                     /protein_id="WP_013369727.1"
                     /transl_table=11
                     /translation="MNDKLKGLFVGLTVGMMITGATAMAASGTSVNAVVKKFDVFLEGT
                     KKNTAEGLIYNGNTYISVKDIGTAESRPISIKSNKLYLGKQQNIITENQALDILLDKIK
                     NEATKYNLHVMVEGIEGTKYSLRAFEDFPDHIATYGFYYVDKYTGKVTKYDIVNDKEVE
                     I"
     gene            complement(14180..14686)
                     /locus_tag="PPM_RS05405"
                     /old_locus_tag="PPM_1017"
     CDS             complement(14180..14686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821362.1"
                     /locus_tag="PPM_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1017"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_013369728.1"
                     /transl_table=11
                     /translation="MKSHVLIYDGYVSFEIMLATYFMKTKGDIVTIGVSKDPVISYEDF
                     KVTPAVALDEVSAEDIQLLIIPGGDNTQLKTNKQLLALIKALNNDHKVIATICSATELL
                     ELAGVSPKNHVSHPSGLEIHKNIISAKPNKYVDFAIEIGKVMNIYTDDDDFNETIDFFK
                     LFKDS"
     gene            complement(14934..15383)
                     /locus_tag="PPM_RS05410"
                     /old_locus_tag="PPM_1018"
     CDS             complement(14934..15383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016819375.1"
                     /locus_tag="PPM_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1018"
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="WP_043885890.1"
                     /transl_table=11
                     /translation="MKNTGMTRPLDTLGRIVIPKELRTSMGIQAGESLEFYLDVETGLL
                     SMRKYIGVCCHICHSVQDLSYFRHSFLCKKCIQDLKGNIEDCPIPALAVKEAGDSEKSI
                     KRSSSQHLVEHLRRLMREYPTAQQGEYAEWLGVSQSRISQLKKLL"
     gene            15586..16986
                     /locus_tag="PPM_RS05415"
                     /old_locus_tag="PPM_1019"
     CDS             15586..16986
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821361.1"
                     /locus_tag="PPM_RS05415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1019"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_013369730.1"
                     /transl_table=11
                     /translation="MEITPTIQAEVQTYLKRKGLTMTEFGHTIDLNVGTVSGIVTGNRS
                     MSVHQLDSITAGMNLPPDYFYERYIEECIEECPLNWKKISPFLYRCIELGRLDCLQRVV
                     ILLLDNPNYLPSLFEVAENVYQDGYNEAAAYLYKKVAESEKQQHSERLAICQYRLFQIN
                     VGQDRAVNLQAAIEFAPFVDRLDEIEQLDALKDLANVYRSLSMWDKVYEFAHRMGQLGQ
                     LQYHLVHNSKRKGTEPRKKLSRPLFVYIAYAELMCANACDAKGDHAQALAHLRGYSDLS
                     WVKENDPDTLHWLEKFEHWAKINTCVNKLMSGDISVLPDYVEHISGEQHIFAELLNVIE
                     VANRYNIDIDHILQQFEPQITVYRDQEYTSTLTEQQVILEETVRFWYKLAKYNLYKGRY
                     LYGFKCLIEALKKAGIINHALLISNCAGLFFCFSELATPEMQAQFYSAYKEVWEKNDQE
                     DSFNFGNN"
     misc_feature    complement(17179..17193)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.45"
                     /tool="antismash"
     misc_feature    complement(17182..17196)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.01"
                     /tool="antismash"
     gene            17213..17467
                     /locus_tag="PPM_RS05420"
     CDS             17213..17467
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369731.1"
                     /locus_tag="PPM_RS05420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="WP_013369731.1"
                     /transl_table=11
                     /translation="MNKDETVTLTQQIEHARQHLLDLYAEYGLGHACVLEQSMLLDELI
                     NQFNRMFQTRKQPHPVLDQILNNDDGMFSLSPHSFYAKL"
     gene            complement(17669..18892)
                     /locus_tag="PPM_RS05425"
                     /old_locus_tag="PPM_1020"
     CDS             complement(17669..18892)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369732.1"
                     /locus_tag="PPM_RS05425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1020"
                     /product="acyltransferase"
                     /protein_id="WP_013369732.1"
                     /transl_table=11
                     /translation="MSKPRIAEWTELRGLAYLAVVLQHCIGEYIYRSDIQQPDSVMLAM
                     LYHLTRFGTPTFVFLSATLLFYNGNKPIGYSRYIGRRFRDIYVPFLCWTVVYWVCTQNW
                     STAQWGNLSFYKGMFEEMIIPVSGYHLWFVVMIFQFYIWFPLFAKATEQIRTFLRRYST
                     KKRKQLVLAVMLIAAAAYALLLQWSYYDMSAWSAWLPSFGQTLLDYRTYNFVMYFFYFM
                     LGAVCAYMTDTWRGLAQQTLPWNVFVFIGLFMLMGHTMLIQSGDTINLNISTYLKPSTF
                     VLIVSQLLLLYGLLLHLQKDPRTEPFRRMLNWIGRYSFGGYLAHALVLSFISYYTRPLA
                     LGDHHFTATLITFVVVASVSLGISWFFAHLPGGNWIVGSKGRQRLNWRPNFQFLSSKRA
                     SKSTQELS"
     gene            19111..20118
                     /locus_tag="PPM_RS05430"
                     /old_locus_tag="PPM_1021"
     CDS             19111..20118
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429118.1"
                     /locus_tag="PPM_RS05430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PPM_1021"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_013369733.1"
                     /transl_table=11
                     /translation="MKKTLLVYMLLIAAFALYVFRYEQTGRLNGAWEEKGLRGSIGETY
                     MMITFQSGLEYWKSGLKGFEDAGDALGVTVEYRGATRYDAQEQTTVIEQAIARKPAGIA
                     ISAIDPHSLIPVINKALDADIPVVLFDAGAPGSRAYTFLGTDNYKAGVTAAEKMAELLG
                     REGQVAVLTLPGQQNHEERSRGFRDTIQRQYPAMKVVEVVDGRADVMVSRDESQRLMKA
                     YPKLAGIFVTEATGGTGVGEAALSQKSSHPLKIISFDTNKATLDMIRDGTISATIAQGT
                     WNMGYWSLQYLFHLHHHLTIPAPSSSGDNTPLPVRVDTGISVVTRANVDDYYAK"
     misc_feature    20123..20137
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.23"
                     /tool="antismash"
ORIGIN
        1 atgcttctaa agctgtcccg gtcagaggga gtggaggaat tgttgtcact gctgcaagag
       61 atggaaggta tccgttcagt cgagaccaaa tccaattaga cgactttacg gctcatttag
      121 tatctttttg tcgaacgctg acagactcat ttaacagtaa aatactttaa aaataatgat
      181 tgaaaacgct tccttttgtg tatatactct tactacatca cagagtcagc agcttagaaa
      241 gcatcagggg ataagcaaca acgacctcat gcgtatgcac aaggtcgttg ctgttatccc
      301 gttttgaaag acaggttatt ttactttgac gggttctgga tattttttac ctagcgtatc
      361 tacagtaact tttttcattg tagctggttt ggtaggtttg tcattgctat cccgtttgga
      421 gttgacgata gcgtcgacca cgtccattcc ggacgttact ttaccgaaag cggcatattg
      481 accgtcgagg tagtccgcat cggcaaccat gataaaaaat tgcgatccgg ccgaatccag
      541 atccgccgag cgggccatgg ataatacgcc acgtgtatgt ttgagtgtat tgttaacgcc
      601 gttgctcttg aattcccctt tgatactgta gccggggccg cctgtaccgt taccttgcgg
      661 atcaccaccc tgaatcataa agcctgggat gacgcggtgg aaaatggtac cgttataagc
      721 tcccttttgc accaaggaga tgaaattgtt aaccgtgttc ggtgctactt ccggatacag
      781 ctcaagcttg attttcttgc catcgttcat gacaatcgtg acaactggat gtgaaacagt
      841 cttgcttttg tctttagttg cagcgggcgt tgtagtgctt gtccggcttg cggcttccac
      901 atcggccgct tttgtgccac atccggcaac cagcacgagc atgatggcca gcaggcacaa
      961 tgtgtaccat gggcgtatcg attttcggtt cattaatatt cctcctgaaa ggttggatgg
     1021 tgtaacatcc taatttatag tttggggaca gcgcagaaca cttttccatt tactatcata
     1081 ccttttttgt tggggataag gaaatacggg tttgaaagcc gtattcttga cccatactgc
     1141 tgctattccc aaggaaaggg gcaggatcat gatggaggta gacaaaaaac tggctaaagg
     1201 tctcatatgg ggtatggcgt tcagtctgcc ggtttgggta ggggtgctgt attcagtaca
     1261 acatattcgt gactggctat aacataaagt gtaaagatag gccaaaaccg caatggtttt
     1321 ggcttattta tatttgtgcc agtccaaatc gctgttattc aacaggtgtt caaagttgtt
     1381 gtccagcttc ttttgttcag ctttttttgc ttcgagggca cgttgccgtt cgtcttcttt
     1441 acgcttgtcc tgttctgctt gcgcttcatt ggcttgagcc ttaagcttgt tcagcacgtc
     1501 ctgactcaac agatccttta acgtagcagg tttgtcctga gccgcaggag cagcgaaaga
     1561 cgaatttctc tttttagcca tgtcatcatc tccattccat tcgattatat cagcttcttc
     1621 gtggttgttc cacgatgaaa ggctaaggtc tacggtagac ttttctaatt tagagggtaa
     1681 taatggaatg aacagaaggg acgtgtggca gcatgcatct atattggaag cgaaacctga
     1741 ttgttttgtg gatcggagta ttgttttgca gcatggccta ttccgtgtcg attccgtttt
     1801 tacctatttt tctgaatacg gaattgggtg ttaacgatca cctggaacta tggtcgggga
     1861 ttgcctttgg agttactttt ttagcgagcg cgttgattgc tccgttttgg ggttcgctgg
     1921 cagataagta tgggcgtaag ccgatgttga ttcgatcagg cttcagcctg gctgtattgt
     1981 atctggtatg tgctttggtg acagacccat atgtatttgt aggagttcgc ttgtttcaag
     2041 gactcctctc cggatttatt cctgcggcga ttgcgctggt cgggacgggc tcgcctgaag
     2101 aaaaaacggg ctacgccctt ggcattatgg cgactgctgg agcgacgggc agcattatag
     2161 ggccgctgat tggcggtgtg gtgagccatt attatggcaa tcggaatgcc ttttatttct
     2221 ctgcggcact tgtattggta tctgcgttca tcgcgacgtt tggcgctaga gaggatagct
     2281 tcaagggcac cagtacccgc tcgcatgttc gtgatgatat caaagaggct attgctaatc
     2341 gtccgttgta ctttttgctt attctggctg gattaagtac cttttccgtc atgatcttgg
     2401 aaccgttaat tacggtgtat gtgcttgaaa tgggcgtgga tcgcagccat gcgtctttaa
     2461 gttccgggat tgtattctca gctgtaggca ttgcggcggt gctgatggct ccccgatggg
     2521 gccggattgg agggaaaatc ggcttcgccc aagtgctgct gattggactg atcggttcgg
     2581 gaatcgggaa catcttgcag ttttttgtaa ccaactttgt tggttttggt gcgcttcggt
     2641 ttggatatgg attgttttat gcgtctgtca tgccggcgat caatgcaatg actgtggaag
     2701 tcaccaagcc ggagtttcgc ggacgagcct ttagcctgaa tcaatcagct acccagctcg
     2761 cgacgatggc gggaccgctg attggcggca tgcttggcag ttggatgccc attcgctgga
     2821 tcttcgtatt aaacagtggc atcttgctgg ttgcagcgtt gttgctatgg gcgaagggaa
     2881 aaaacgtttt cccgatttca gcccaaaata acgcaacgga tcagaatatt cattctgccg
     2941 gataggccaa ttagataatt atcccaaacc cttattttta gtatattatt cataaccctt
     3001 tacactgatc atatgacagg gagggatata ttatgataag agacgacatt ttgcgtcaac
     3061 agcttgagaa tgctcgtcaa aagctgtata ttttgcaagc aaaacatggt tttaatcatg
     3121 ctagtgtgct caaacagtct gtaattatgg ataacctcat caatcaatat aaccaccttt
     3181 tttatataaa agaaaaaaag ccgactgcct agatatagcc gactgggcga gaacttttag
     3241 aaaggccact cgccctagta ttgtaggact gcaatatctt taggtacggc ttgtttggtg
     3301 tgcactcatc aagaccccta gaataacgac caaaccgcca atgatttggc gccatgtaat
     3361 cgtttcgtgc aatagtaaga cagagaacaa caccccaaat atcggaacca agttcattaa
     3421 agaaacggaa ctgctcggtg acagcttgat taatccgtaa ttataaagca aaaatgcgat
     3481 aacagagcag aacacaccca gatacatgag caacataaac gatcccgttg tcggagcctg
     3541 ccaactatcc ttttccaata aggctaacgg tatgaaaaag atactacctg caacggtttg
     3601 ataaaaagat aacgtcaccg gcggatattt gtccacaacc ttacgcgtca tgaaagtgta
     3661 aaacgcccac gcaaatccag ttccaatcaa gattaaattt ccgatgagtt gattcttacc
     3721 atccgagctt tcgccaacgg aggttaagaa atataccccg atcatggcca gtgctatgcc
     3781 gcagatttta tatttggata atttaacttt atacaaaata aattcaagca gcgatgtaat
     3841 tgccggatac gatgcgacaa ttaatgctgc gttggaagcg gttgtcaggc taacccctat
     3901 attctccatt gagaaataaa gagtgattcc aagaacccca ctaaacgaaa tcgtagccaa
     3961 atcctttggc tttactttga catgttcttt tttgattagc aaaacgatac ctagtacgat
     4021 ggaagctatg ataaatctgg atagacccaa ggtaagagga gggaacgtcg tataggctgc
     4081 tttggtggca ataaacgatg tgctccagat caataaggct agaatcgtag aagtatagta
     4141 aatccggttg ctttcgctgt gatgagctat gactttgttc aagttgtatc ctccctgagt
     4201 tcatccccta tgaaagtatc atagtagcta ctatagttac tactatgaaa atactactaa
     4261 aaagatagtt tgtatatcag tttttgtcaa ggggaagtga tatagtaagg aagaacatga
     4321 attgaggaga agacgtcatg aaatcaaaac caaacatatt agaaattcta cgtgatttga
     4381 attttagtga atatgaagcc aaggcttatg tgactttatt ggaaagctct ccactttcgg
     4441 gatatgccgt ttcattgaac tctggagtac cgagatccaa aatttatgag gttttgtcgg
     4501 ggatggtcaa ccgtggggac atcatggtaa gtcaagaaaa tacacctctg tatgtgccgc
     4561 ttcctccaca tgaattgatt gcccagagaa aacgcaaagc agaacagatt tttaatgtgg
     4621 cgcaagagag tttggagcag tacacagcat cgtttcaaaa tagagagaat atttggaata
     4681 tttcgggtta tgaagccatt atcaatcgca tcaacgaagg tgtgaaggga gcaaaacacc
     4741 gaattttact ggaaatttgg aaagaggatg ccgaggtgtt ccgggatgcc ttagagcaag
     4801 ctgctcagca aggaattgag gtgatccttg tagcatatgg tgatcttaac tttgattttg
     4861 ctactgttta ccgtcatgat atgagtgagg agattacgtc cgaaatcggt ggtcggtgga
     4921 ttgtgcttag cgtggatgac cgggaggttg tagctggcat actttcactt ggtgatgaca
     4981 gccgcgctgc atggacgcta cacccaggcc ttgtaatgcc gattacggaa gtgattattc
     5041 atgatattta tatcatggaa atcctatatg agttccgtga agaattggag gcaaaatttg
     5101 gccctaatct aatccatctt cgcaataaat ttgctatggg tccgaatgga aaaggatatt
     5161 atgttccttt gactgaaaag agcattaaac gtgtatagag attgtccgag gtccgttgtg
     5221 caaaaataaa aggcccatgg aatatgattc catgagccta atttattgaa tgctgtgttt
     5281 aggatgataa ccacttaggc attcttttta ttgaaggttt taggcataaa actagtttta
     5341 cgctttgaat aaaccggatt ctttgacttc agacaggaag ttgtggaact caggtatgtt
     5401 cagctgttgc tgagcatcgg acaaagcgac tgccgggttc gggtgaactt ctaccatgat
     5461 gccgtcggca ccagctgcca gggcagcctt ggcgcaagga gccaggatgt ccttacgtcc
     5521 tgtagagtga gttacgtcca ccagtacagg cagatggctt tcctttttca aaatcggaac
     5581 agcggaaata tccagcgtgt tacgtgtcca tttttcatac gtacgaatac cgcgttcaat
     5641 caacatgact tgtgtattgc cacgggaaac gatgtattca gcagcatgaa ggaactcttc
     5701 cattgtggca gccaatccgc gtttgagcag aaccggagtt ctggtttcac ccgcagcttt
     5761 aagcaattca aagttgtgca tgttgcgcgc gccaatttga atgatatcga tgtatgggat
     5821 ggcttcctcc aaatgtcttg gatcgacgat ctcactgatt gtagccagcc cgaactcgtc
     5881 gccaacgcgt ttgagaattt gcaggccttc aatacccagc ccttggaaat catacggaga
     5941 tgtacgcggt ttgaacgcgc caccacgcag aatcggcaca ccggcttcct tgagagccgc
     6001 acctacctcg cgagtttgtt ggtagctttc caccgagcaa ggacctgcaa ccatgatgga
     6061 ggctttgccg cccaccagtg tatctttaac cttgataacc gtgctatccg gctgattttt
     6121 gcggctgaca atcagatgtt ttttgtgttc ttctttttga tagttcagag aagccttgaa
     6181 aatatttttg aacagctggc gaatcgtagc atcgtcgaaa ggtccgcgat tagctgcgat
     6241 cagcttgtcc agcatttgtt gctcacgcac tggatcaaag tcaggtactc cttgagcttc
     6301 tttcaatttt cctagctgtc ctgccagttc agcgcgttgg gacagcagct ccagcaattg
     6361 caagtttgta gcatcgagct gttcccgcaa cagctccaaa gaattttcat tggttgacat
     6421 acagtacacc cttcccgatt taaaaattgt ttttctttca gcccatagac ttttgcagaa
     6481 aataacacaa aaaggcactc gtcgcaaggg acgaatgccg tggtaccacc ctaattacag
     6541 aagtatacat gcaagtcgtc aacgtcattc aatcgacggc agtaacctct gagcttgatg
     6601 cccgtaacgg gggcttccgg aaacctctac tgcggtcaaa ggaatgaatc cttctgtcgt
     6661 cggttcaagg ctcgactcgg gagtgaattt caacgcggga ttgcggtacg ctctcagcaa
     6721 tacgtacctt tctgtgggaa tccgatgacg cttacttgtc tccgtctatg tctttgttca
     6781 tggtattcaa aagatttgac cttattttaa acaaagtgga tgcagaaggc aagccctgat
     6841 ttccgattct agtttttgca ttccctatct gtgctatcat cttgcttgat ctctaggttc
     6901 gggcttcgct gatgcgactc ctcgtgggtt atcttcggct atgccatcgt ccgtatgagt
     6961 tttgtccgca gtcctgcggt catcctcttc tacaggattc aaggttttat agcgtttgta
     7021 ctccatatca gcttgagaca tcggatcttt atacatagga gattagtcaa ctcctttcgg
     7081 tatatacact tcattacccg catagcaaga tgagaaaccg ctttcttatc tcctataaca
     7141 tgcagtaatt aatccagaat atcgtcactg tccagttgct cttcttcatc cccatcggta
     7201 ccattcagca aatctgtacc atgcaggaat tcagcaggcg cagagggatc aacaggactg
     7261 ttcggtgtca gttcatcggc atcaggtacg tcctccagag gagtatcagg cccctcgatc
     7321 agattctccc agtttgtttc tgcattttgc agggaaggct caaaatcatg atcctgtagc
     7381 tcagtctttt gattgtcgcg atttgccatc taactcagct cctttgcttt ttgttgctta
     7441 tttcgacctt acccaaaccg cagaacggct aaacttagag ttagtgtgtc tgtaaaaagt
     7501 taaaatcatg cgaataggga tatgctcttt cccaataagc gtttttttgg taactgctgt
     7561 gatatgataa agaggagttg gagggatatg aattggaatg gtacatgttt ggtccgatga
     7621 ttagccggat ccgagtaggt caaaaggcat ctactccagg ctattcgcgt accgttattc
     7681 ggcgtccgga tggtttatac tggacagacg gcggacaggc cggaaaaata gtagaaatac
     7741 gcgattattt attctccgat atttggacga tctatgagga tgaagaatgt gaaccttgga
     7801 tagggcttag agagcagatg gagcaacgcg aacaggaaat gatcattaac caatatgaag
     7861 attttacaaa taatgattaa aaagaacatg atacccttat tttgaagaag gtatgaacat
     7921 catcgtatag aataatatag tttcaggaag ataaaatgtt aaaacatata caaatttgta
     7981 aatcctacta cgtaactttg aggtgcttaa tatgaggcat gtgcccaaag ctgtcgccgc
     8041 tctgctagcg gtcattgtga tactattgtc gctggaccac atcggctatg cggccaaaat
     8101 gaccccggaa agggagtata agataccctc ctgggatatg agatggggag cagaagacga
     8161 ggatggctct ttagatgagg taactgatca cagtaaggtc tggatgcata ttgaagatga
     8221 tacacagctg ctcaagcagc caggcaatag aggcaccgcc tggattcgta ttaagctacc
     8281 ttcgttaaat gatgaaacac cagcggtgct ttttgaaaat atttatggca ggcacattac
     8341 actgtataag gatggcacca atttttatga atcgtaccgt ggctataatt atgagaataa
     8401 tcgtattctg attccgctga agccagaaga cagtggtaaa acattataca tatggacgga
     8461 aagcagtaag aatagactgg gcattatcgg aaatgtgatg actggtgatt atcgtgactt
     8521 gttgggaaac ttggtcagaa tggatgtctt ggatattgta ctgggcagta catttatctt
     8581 tatcgccctg gtgctattga tctgctcgtt tttcctgttc cgtccaagta tggccatgtg
     8641 gttgtcccta agtgcgattg tattgtcgat cggtctgatg attgtaacgt attcaccgtt
     8701 tttatatacg ttctatcgag gctatggcaa gctgtattta caactttttg atgtggcgct
     8761 atttattctg ttgccttcat tagccttctt ttttgagcaa aatatcaatt caattttact
     8821 gattcggaaa ttcagaaaat tgttaaccgc ctactctttg ttctgcttca tcatcatgat
     8881 tgtgaattta ggagcacagg agcgactcaa cgatgtatat tatttcttca gtgtaatcgt
     8941 cctcggtata ttgctcgtag ctttgatggt acttttggta tttgcttcga ttcgcatggc
     9001 gcttaaggga gaccacgaag cgatcatttt atcgacaggc tttgcatttt ttgcagtcat
     9061 cacgatcgca gaactcagct ggttctttat ccgggacgga cactacaata tgtttttatg
     9121 gaaatggggc gtgttcggtt ttgtcctggc attgattgcg atcttgggca gaaggctggc
     9181 ggaaaagcac aagcaggtgg ttcggtattc cagagaactg gagatgttca ataatgagct
     9241 tcaacgttca gagaaaatgg agattattag cgatttggct gcatctgtag ctcatgaggt
     9301 acgcaatccg cttcaggtta cacgtggatt tcttcagttg atgagcaagc aggaggatgg
     9361 taagaacaaa gactatctgc atatcgctct ggaggagttg gatcgagcgt ccgcgattat
     9421 tactgatttt ctgacttttg ccaagccgga gtttgaccat accaaaacgt tgaccatatt
     9481 ggatgagttc aaacatatag aaggaattat cagtccaatg gcaaatctgc aaggtggtaa
     9541 aatttcgctg gatattcccc aggaaatcaa agtgcgcggg aattcctcca aattcaagca
     9601 ggcatttatc aatattatca aaaacagtat tgaagcgttg cgagaacagg gacatattca
     9661 tatatgggct tatgtggaca atggagaagc agtcattcat attcgggata atggtgaagg
     9721 gatggatgct cagaccttat ccagactagg tgagccttat ttttcgaata agactaaagg
     9781 cacgggtttg gggatgatgg tgacctttcg gattattgaa acgatgaatg gtaaaatatc
     9841 ttttacaagt gcaaaagggg tgggaacaga agcgaccatc cgcttccccg tagccggata
     9901 acatccggct tttttgcgtt cggagaaaac ggagggaagc ttgctgagcc cacccgcttg
     9961 agattaaaaa gtatagatta aataagctac aagaaccaat ctaccacatc gcgcgaggtt
    10021 tctgggatgt agcgagcacg cctgaagggt ttggagggat aaccagataa aattgatcag
    10081 acgtttcctc taccgttttg atttggatat gatcggggat cacgactcct aacacatcac
    10141 gaattgcaga tttgggatct gccatcagtt tctctctgaa actggcatcc tcccaagctt
    10201 tttgaatgac ttgtgtttga agaacttcag tagccatcaa aaatcaccct ctcattcaat
    10261 tggttataat tacctagtca gtataccacg taagactcag aaaaatctag cattatttca
    10321 tatttttgga gagccaataa tcaagcccgc ctcttcgcaa atgtgagcgt ccgccttcaa
    10381 tttctgctgc ctcttcgctg agctctgttg cgatggaatg tgcgaaccta tacagaccgt
    10441 ggatggaagg ctccatcgtc tctagctcct ggactgattg attcgcaatg ttcgcatagc
    10501 tggcgagcgc cccgcgtaca taaatcgctt cctgaatttg ttgtggtcct agtccttcac
    10561 agtacgccgt cttttgttcg gcgctgatat gggacaatag gcagttatag ctatgttcca
    10621 ccaagtcttc tgaccaatct gcccaatcat ccgacatttg gagcacgagc aagctcaaat
    10681 ctgtcatatg ggtaacagtc tggatcagat cggcatgatc tgcgagcaat aaggcacccg
    10741 ttccggccat ttttaatggg ctggctttta gtgcgacctt atttctttca ccttgaaaat
    10801 agtcctctgt tccttcggat atcacactaa cggcccattc gtccacatac gtcctggcat
    10861 atgaccaaaa aggagaggtt gccggaaaaa gctcctgata aatgtttaga cactcggtat
    10921 agaaaagctg acttaaggca agttgcgttt tacggttgtc tgctgctgtg tccatcacgt
    10981 cgtcttgaat taaataatga gccatgacga acacgttgcc gagtgacagc ttgcgacatg
    11041 tttcgggaga cagtccggtc agttcctgca gccaaaatgg aagcaaatag catatgtaat
    11101 tacgcgtact gtcttcccgc aacggattaa accgcgccag gtagtctaac ccctcttgct
    11161 gaaagggaac cggaaatgtg gccgtccgtt cctccgcttg gcggaatacc ttttccaatt
    11221 cttctttgta tgcaaaatac cattccatgg ctaccacccg catctcttat aaatgttttt
    11281 gtagcgactt atagttgtta tccgccatta tataagaggt tgcgatattg caatattatg
    11341 ttatttttac attgagaatt atgtgaaaaa gatatcaaca aaaatcccgg tcgggaagat
    11401 cccgccggga ttttgttttt ttaaaattag atgatctcca aatagtcaag ataagcatcc
    11461 catgtcccat catcggctgt tacaacaagc tcaatctttt gatttccggt gccatggttg
    11521 acatttttta aagtatagac cgcaggactg ctcccgccga agtagaaggt acccttcgtt
    11581 tgtccaccaa ttttcaagtc aactttggcc atgttggaat tatttgaagc accccggagt
    11641 gaaaaactat gggtaccgct ggtgaaattc tgtgtgaatt tcaccgaatc attgttcgtg
    11701 tataaagcca ctccgttgaa cggcgagctg atatttgaag tgtactgacc gctcttcgtc
    11761 atatttactg cttcgatttt tgtgctcgtg tttggcggtg tttcgttgtt tttgccgtca
    11821 ggcgctaccg cccggccatt gcttggagag atcataccag agcaaaggtt gcggtttttg
    11881 agattctgtg cgatttgtgg gatcgcttgg agtgtagtct gatactgatc atgcataagg
    11941 atcacatcgc cgtttttaag tctgcttgcg gcagctacga tctgtgcggt ggaggcgccg
    12001 ttccagtcct gggagtcaac gttccataac acttcggtaa gaccgttttg gttctcaatg
    12061 gatttgaggg ttccattggt ctcgccatac ggaggacgga acaactttgg tgccgtgcca
    12121 gtaatagact gtattgtttg ctgtgtgcgt gtaatttccg atgacatctg tgatgcgctc
    12181 agttgcgtca tatgcggatg tgaccatgaa tggttaccga tccacatgcc tgctgcttgt
    12241 tgttcacgta cgagcgaaga attattctgc gcgttttgtc caagattaaa gagcgttgcg
    12301 cgtaatccgt tttgcttcag ggcactaagc agtgctctgg tattagaggg attggggcca
    12361 tcgtcaaagg ttaacgctac ataaccgttc gagcaatcag ccgcatgcgc ctgattgttg
    12421 gagattacca gcgaccctgt gaataaagac acggtgattg acataatcgc cgtccatttt
    12481 cctaatttag ctatagacaa ggttcttcct cctaacaatt ttaataaaca gtaaggttag
    12541 ttgattttag agtcgttccg cccttaggat tatctgtcgt taatcgtaat ggtattatta
    12601 gttacattgg cactgccgta cgcataaata agaattacca tttggttggt agttggcgct
    12661 gtagtttaca gaaatatttc cgatttgctg gtgtgtcttg gtttcgtcga atttcttgcc
    12721 tttacggaat aatgctgact gtgatgcaat gcattctgta gtagcttgat acaacattta
    12781 tttccaaaaa tatagttgta atcgattaca aattaatatt atcatgttac ccttcatatt
    12841 taacctgaaa aacttcaagt tatattgtag aaagtttagt tgtttatttt tgctcactct
    12901 acacgatagt gttctcaagg agcgcgtgaa gatcgaaggt tgggtgtaat tgtgatagca
    12961 atgctcatga gctctttttc ccgtcttatg gttacttaac aggcgaaata cgaataaaaa
    13021 aagctgaaag agaaaatata gatgaaaaag ggtgaaagga gggtccacaa catgaaaaaa
    13081 caatggaaat tgaccgctgc tatcctatat ggaggagtaa tgatgtttgg tgctacaagt
    13141 gccgcaggag catacagtat ggaatcagag cattcgttgc aagctctcac tcccaataat
    13201 tcagtccaag gggaagccca acagtggaat gttgaaccac aggacgatga cgggcacgga
    13261 catgtgcaca gacatagaca cggtaaaaga cctggcggct tgaatcacca tctcaacgag
    13321 aaagtagcta ggctgctggg catcactcct gtccagttag agaaagagct gggacagggg
    13381 aaatcgttgg ccgaggttgc taaaagcaaa ggaattcaag aggatcagct cattgataaa
    13441 ttgaagaacg aaatgaccgt ggatttgaaa cggcttgtga accgtaaagg tccgattaca
    13501 tttgaccgta aatctggaac ttcgaatgaa gctcaattga agcaatagtc tgggagtaaa
    13561 attgttttac aataaaaaag gatggggaga acccatcctt atatttcaac ttccttatca
    13621 tttacgatgt catatttagt tactttacca gtgtatttgt ctacgtaata gaatccataa
    13681 gttgcaatgt gatcagggaa atcttcgaaa gctcttaaag agtattttgt tccttcgatc
    13741 ccttcaacca ttacgtgtaa attatattta gtagcttcgt tttttatttt atccaaaaga
    13801 atatcgagtg cttgattttc tgtaataata ttttgctgtt tccctaaata gagtttatta
    13861 ctcttgatgc tgattggtct gctttcggca gttccaatat ccttaacaga gatgtacgtg
    13921 tttccgttgt aaattaagcc ctcggcagtg ttcttttttg taccctctaa aaatacatca
    13981 aactttttca caacagcatt tacacttgtt ccagacgcag ccattgcggt tgcacccgta
    14041 atcatcatcc ctacggttaa gcccacgaat agccccttta atttgtcatt cattctaatt
    14101 acccctttta tgtatgtaaa tttatttatt aataatatcc caaatatcac catacataaa
    14161 gtgattgttg tgaggagagt cagctatctt taaaaagctt aaaaaagtct atcgtttcat
    14221 taaaatcatc atcatccgta taaatgttca tgaccttgcc tatttcgatt gcaaaatcta
    14281 catacttatt gggtttagca gatatgatat tcttgtgtat ctccagaccc gatggatgac
    14341 tcacatgatt tttaggagaa acacctgcta gctccaatag ttccgtggca gaacaaatgg
    14401 tcgcgatcac tttatgatca ttattcagtg ctttaatgag agctagaagt tgcttgtttg
    14461 tctttaattg agtgttatct ccaccaggta taattaggag ttggatgtcc tccgcagaca
    14521 cttcatcaag ggctaccgca ggcgtaactt taaaatcctc ataggaaatg acaggatctt
    14581 tggatactcc aatcgtaaca atatcccctt tggttttcat aaaataggtt gctagcataa
    14641 tttcaaaact aacataccca tcataaatta gaacatgtga cttcatttat acacccacta
    14701 accatttttc tgttttaagt ccgttaaaag cgtttttagg aagtttacat atagtcagaa
    14761 tatatcatct taaagagttt aaatccatat tttacagcaa tatcatttgg aagttttgga
    14821 atctaattta ttaaattttg gtcattatgg tttcgaagtt aaaaaataac cagtcgcctt
    14881 gagataaaca gcgactggta attggagttt actgggatca agttaatcaa cacctataat
    14941 agctttttaa gctgagatat acggctttgt gacacgccaa gccattcagc atattcgcct
    15001 tgctgggctg ttggatactc acgcataagt cttcttagat gttcaaccaa atgttgcgac
    15061 gatgatcgtt ttatgctttt ctcactatct ccagcttcct taacagcaag agcaggtatt
    15121 ggacaatcct cgatgtttcc cttcaaatct tgtatgcatt tcttacataa aaatgaatgt
    15181 ctgaaatagc ttaaatcctg gaccgaatgg catatgtggc agcagactcc aatatacttc
    15241 cgcatactta acaatccggt ttcaacatcc aaataaaatt ctaaagactc gccagcttga
    15301 atacccatag aggttcgcaa ttcctttgga ataacaatcc ggcctaacgt gtccaaggga
    15361 cgtgtcatac ctgtattttt caagtgacct tctcctatca taataatcta tcatccaatg
    15421 atctcctaat aaaaatataa aaatctataa agtaaaagta tttattgatg ttccaaaaga
    15481 tggtattatc atgaatgaaa aaacagtaat tatactattt gtttcaaaac tatatgaatt
    15541 attgaaaatg ggaatctatg aagatgctga aagggtggtt tatccatgga aatcacacct
    15601 acgatacagg cagaagttca aacctatctg aaacgaaaag gcttaaccat gaccgagttt
    15661 ggtcacacga tcgatttgaa tgtaggtaca gttagtggta ttgtgacggg caaccggtct
    15721 atgtctgttc accaactgga tagtattact gcgggaatga atttaccacc ggattatttt
    15781 tacgaacgat acattgaaga atgcattgaa gaatgtccgc taaactggaa aaaaatcagt
    15841 ccgttcctgt accgatgcat tgagctaggg cgattggact gcttgcagcg agttgtcatt
    15901 ctgttattgg ataaccctaa ttatctgcca tcgctctttg aagtcgccga aaatgtatac
    15961 caagacggtt acaacgaagc agccgcttac ttatacaaaa aggtagctga aagtgagaag
    16021 cagcagcatt cagagcgatt ggcgatctgc caatatcgct tgttccaaat caacgtcgga
    16081 caggatcggg ctgtaaacct tcaggctgcc atcgaatttg ccccttttgt ggatcgttta
    16141 gacgagatag agcagttgga tgctttaaaa gatttggcaa atgtctatag gtcattaagt
    16201 atgtgggaca aggtgtatga atttgcacat cggatgggtc agttaggaca actccaatat
    16261 catttggttc acaattccaa gcgaaaagga acagagccac gaaaaaagct aagcagacca
    16321 ttgtttgtat acatagccta cgccgaattg atgtgtgcta atgcttgtga tgcaaaaggc
    16381 gatcatgcac aagcattagc acatcttcgt ggttattccg atctaagctg ggtgaaggaa
    16441 aatgatccag atacactcca ttggctagaa aaatttgagc attgggcaaa aattaatacc
    16501 tgtgttaata agcttatgtc tggagatatt agtgtgctgc cagattacgt tgaacatata
    16561 tctggagagc aacatatatt tgcagaactt ttaaatgtca tagaagtagc taatcgttac
    16621 aacatcgata ttgatcatat tcttcagcag tttgaacccc aaattacagt ctatcgtgat
    16681 caagaatata cgagtacatt aacagagcag caagtcatac tcgaagaaac tgtacgattc
    16741 tggtataagt tagctaaata caacctatat aaagggagat acctttatgg gtttaaatgc
    16801 ttaatagaag ctttgaaaaa agctggtata attaaccacg cactacttat ttccaattgt
    16861 gcaggcttat ttttctgttt cagtgagctt gctactcctg aaatgcaggc acaattttat
    16921 tctgcttata aggaggtgtg ggaaaaaaat gatcaagaag acagttttaa ttttggcaac
    16981 aattagcttt ttactggtag ttggattacc agttccaact gaaatcccaa gcgctaacac
    17041 agtccaagtt caaggacata ttggcacagc ttagtcgatt tttttgtttt tttcattggc
    17101 cagcttattg ctggtctctt tttgtattat tttgtaattt tttgcttcaa aattgatcct
    17161 gacgtatttg tacatccctt cttaaaatga gattcagtag gaggtatgta ggatgaacaa
    17221 agatgaaacg gtaacgttaa ctcaacaaat cgaacatgcc agacaacact tgcttgatct
    17281 ttacgcagag tatggcttag gacatgcttg tgtactggag cagtctatgc ttttggatga
    17341 actaattaat cagttcaacc gtatgtttca gaccaggaag cagcctcacc cggttttgga
    17401 ccagatcctt aacaacgacg atggtatgtt cagtttatcc ccccattctt tttatgcaaa
    17461 actgtgactt ctcccacgta atgcttataa ttattctata taatgactta ttttaaaaca
    17521 aaatacatat ccatgtcata aaatgttaat cagttacgga catgattcag catgcttaga
    17581 caacaaaaaa agcagagctc aatacgtgag ccctgcgaaa gtccttgagg gtgttcgaat
    17641 cccccatatt gaacgctgaa gcagaagatt agctaagctc ctgtgtgctt ttggaagcac
    17701 gtttggagga gaggaactga aaattaggcc gccagttcaa tcgctgtctg cctttggagc
    17761 caacaatcca gttgccgcca ggcagatggg caaagaacca actgatgccc agggaaacac
    17821 ttgccacgac gacaaacgta atgagcgtag ctgtaaaatg atgatcaccc agtgcaagcg
    17881 gacgagtgta ataggatatg aaggatagca cgagtgcatg ggccagatat cctccgaagg
    17941 agtagcgtcc aatccagtta agcatacggc gaaacggctc ggtacgcggg tctttttgca
    18001 aatgaagcag cagtccgtac aacaaaagca actgcgagac aatcagcacg aaggtgcttg
    18061 gctttaaata ggtagaaata ttgagattga tcgtatcgcc agactggatc agcatcgtgt
    18121 gacccatgag catgaacaga ccaataaaaa caaatacatt ccatggcaac gtctgctggg
    18181 ccaatccccg ccaggtgtcc gtcatatagg cgcacactgc gcccagcata aaatagaaaa
    18241 aatacataac aaagttataa gtgcggtaat ctaacaaagt ctgcccaaag gacggcaacc
    18301 aagcgctcca tgcagacatg tcatagtagg accattgtaa cagcaacgca taagccgcag
    18361 cagcaatcag catcacagcc aaaacaagct gcttgcgctt tttggtgcta taacgacgta
    18421 gaaacgttcg aatctgctcg gttgcttttg caaataaagg aaaccaaata taaaactgaa
    18481 agatcatgac cacaaaccat agatgatatc cgctgacagg gatgatcatt tcctcgaaca
    18541 tacctttgta aaaggataaa tttccccact gcgcggttga ccagttctga gtacacaccc
    18601 aatagacaac cgtccagcag agaaaaggaa cataaatatc tcgaaaccgt ctgccaatat
    18661 aacgggaata gccaatcggt ttgttaccat tataaaataa cagcgtcgca gacaggaaaa
    18721 cgaacgtcgg tgtgccaaaa cgtgtcaaat ggtacagcat cgcgagcata acggaatccg
    18781 gctgttggat gtcgctgcga taaatatatt cgccaatgca atgctgaagc acgacagcga
    18841 ggtaggcaag accccgtagt tctgtccact ctgcgatacg cggcttgctc atccatatca
    18901 ctccttttcc tcaagattcg cacatgtttt tcctagcaca attgtaggta ttgtaccgta
    18961 ggaacattag tgcaggatta acgccacctg aaagtaagaa gagtgaagta gttccaattt
    19021 aatatgattg cgtttacaat ctaagtgaaa ccagaataaa ttaaagtgaa tttataactt
    19081 aaggatacgc acaggaagag gagaggaagg atgaagaaaa cgctgctggt gtacatgctg
    19141 ctgattgcag cctttgctct ctatgtgttc agatatgaac aaaccgggcg gttgaatgga
    19201 gcttgggagg aaaaagggct acgaggcagt atcggagaaa cgtatatgat gattacgttc
    19261 cagtccggtt tggagtattg gaaaagcggg ctcaagggct tcgaggatgc tggggatgcc
    19321 ttgggggtaa cggtggagta tcggggggct acccggtatg atgcacagga gcagacgacg
    19381 gtcattgagc aggcgattgc ccgtaaaccc gcaggcattg ccatatcagc gattgatccc
    19441 cactccctga tcccggtcat taataaggca ctggatgccg acatccctgt agtgctgttt
    19501 gacgccggag cgccggggag ccgggcatat acttttttgg gcacagataa ttataaggca
    19561 ggcgtgaccg ctgcggaaaa aatggcagag ctgttgggac gtgaaggcca agtcgctgtt
    19621 ctcacactgc ccgggcagca aaatcatgag gaacgctcgc gcggctttcg cgataccatt
    19681 cagcggcagt atcctgccat gaaggtggtg gaagtggtag atggtcgtgc tgacgtgatg
    19741 gtgtctaggg atgaatcgca aaggctaatg aaagcttatc cgaaactggc gggtattttt
    19801 gtgaccgaag ccaccggagg aacaggtgtg ggtgaggcag cactgagcca aaaaagcagt
    19861 catccgctga agattatttc ttttgatacg aataaagcga cactggatat gattcgtgat
    19921 gggaccatct cggcaacgat tgcccaaggg acatggaata tgggctattg gtcacttcaa
    19981 tatctgttcc atctgcatca tcatttgacg attcctgcac cttcttcgtc tggagataac
    20041 accccgctgc ccgtgcgggt ggatactggg atttccgtcg tcacccgagc gaatgtagat
    20101 gattattatg caaaataaat attggaagcg catccactta aggatgcatc aaatgatgcc
    20161 gaggttacgc ttgcgcaata tgcctttacg ctatcagctc atggtgctgt tcttgctgtt
    20221 tggcatcgtg ccttcgc
//
