LOCUS       NC_016047              21699 bp    DNA     circular CON 13-SEP-2024
DEFINITION  Bacillus spizizenii TU-B-10, complete sequence.
ACCESSION   NC_016047
VERSION     NC_016047.1
KEYWORDS    RefSeq.
SOURCE      Bacillus spizizenii TU-B-10
  ORGANISM  Bacillus spizizenii TU-B-10
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M.J., Rasko,D.A.,
            Daugherty,S., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Whole-genome sequences of Bacillus subtilis and close relatives
  JOURNAL   J Bacteriol 194 (9), 2378-2379 (2012)
   PUBMED   22493193
REFERENCE   2  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M., Rasko,D.A.,
            Daugherty,S.C., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2011) Institute for Genome Sciences, University of
            Maryland School of Medicine, 801 W. Baltimore St, Baltimore, MD
            21201, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000227465.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 01:46:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,304
            CDSs (total)                      :: 4,177
            Genes (coding)                    :: 4,051
            CDSs (with protein)               :: 4,051
            Genes (RNA)                       :: 127
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 90 of 126
            Pseudo Genes (incomplete)         :: 52 of 126
            Pseudo Genes (internal stop)      :: 16 of 126
            Pseudo Genes (multiple problems)  :: 28 of 126
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:59:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4108423
            Orig. end                         :: 4130122
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002905.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21699
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="epipeptide"
                     /region_number="12"
                     /rules="(TIGR04078 and yydH)"
                     /tool="antismash"
     cand_cluster    1..21699
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04078 and yydH)"
                     /kind="single"
                     /product="epipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21699
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11699](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11699)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
     gene            complement(487..1719)
                     /db_xref="GeneID:11241601"
                     /locus_tag="GYO_RS42570"
                     /old_locus_tag="GYO_4415"
     CDS             complement(487..1719)
                     /codon_start=1
                     /db_xref="GeneID:11241601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017418528.1"
                     /locus_tag="GYO_RS42570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4415"
                     /product="Fic family protein"
                     /protein_id="WP_014115808.1"
                     /transl_table=11
                     /translation="MNYEKLSKLFYKIDADSYDKEFIKRKSSYGSYSTSLTVRGFRKGH
                     LTNDSFELFYVNTHELMKLNNEVLLNSSKISSLIRQLPKFVVKPYFNKLIINEAQSNNE
                     IEGIRSTKKELKEALNALEQSEPQHKRFVGLMKTYQFIDQIDSFKSVRDFRKLYDELVA
                     DEIVAEDAPDGELFRRGYVEVNDGNRTTHIGISSEQKITEALDALIDYLDDESHPQLYR
                     YMVAHYYYEYIHPFYDGNGRTGRLIVGSYLSSYLEKYSAITFSYAVNKNKEKYYKALEE
                     IPSPLNRGEMTFYLINMLELLLSGQKGIIEDLEFNLMKLNRIKNYMKSDQWVDYKDERE
                     LFYIIITINVFVNDHVMLSVQELMKISGKSRHIVNKVMDYLEEQGFVELTSRRPKSYKI
                     SEDCLEEILPS"
     misc_feature    complement(2135..2151)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 23.91"
                     /tool="antismash"
     gene            complement(2182..3534)
                     /db_xref="GeneID:11241602"
                     /locus_tag="GYO_RS42575"
                     /old_locus_tag="GYO_4417"
     CDS             complement(2182..3534)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="GeneID:11241602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014115810.1"
                     /locus_tag="GYO_RS42575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4417"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_014115810.1"
                     /transl_table=11
                     /translation="MKNILIRAGISPFDTFNAAEMIVRNSIGGNVGNLVYAYSVFRTLM
                     TEETTITPDYYRINPADAEQINKTYDMYIIPLADAFREDFVPSLRKYTQLIKKLTIPVV
                     VIGVGLRAPFEPKLNEGFPFDQDVKAFVSAVLERSNMIGVRGEITAKYLSRLGFREGID
                     HTVIGCPSMYAFGRELKIRETHITPGSMVTVNSSRLSPKHVLDFITRSMKEFPNHYFIP
                     QWRKEMILTYAGAPAIAKPADNYPVSMEDPAYQNDRVRFFLNVPTWLDFLRQADLSFGA
                     RLHGNIAATIAGTPSLLLPKDARMRELAEYHQLTHVMANEITDQTKLSELIETLDFHQP
                     EKRQAQNFDHFISFLNQNQLDHIYQEKAIPDTVPFDEKLSNTKFLPPVTTVSGCSSTET
                     AKRWEALMALENAKKEKTIKDLKKKVKKYQGTLNRKSVRIALKTANMLSVK"
     gene            complement(3825..5264)
                     /db_xref="GeneID:11241603"
                     /gene="bglA"
                     /locus_tag="GYO_RS42580"
                     /old_locus_tag="GYO_4418"
     CDS             complement(3825..5264)
                     /EC_number="3.2.1.86"
                     /codon_start=1
                     /db_xref="GeneID:11241603"
                     /gene="bglA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391891.1"
                     /locus_tag="GYO_RS42580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4418"
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="WP_014115811.1"
                     /transl_table=11
                     /translation="MGNMTKDFLWGGALAAHQFEGGWNQGGKGPSVVDVMTAGAHGVPR
                     KITDTIEENEFYPNHEAIDFYHRYKEDIALFAEMGLKCLRTSIGWSRIFPKGDEAEPNE
                     AGLQFYDDVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKVVDFFVNFAEACFNR
                     YKDKVKYWMTFNEINNQMDVNNPLFLWTNSGVVVGENENAKEVMYQTAHHELVASALAV
                     AKGKDINPDFQIGAMVSHVPIYPFSSNPEDVMLAEEEMRQRYFFPDVQVRGYYPSYALK
                     EFEREGYHITFEDGDDEILRNGTVDYLGFSYYMSTTVKSDVENDNTGDIVNGGLPNGVE
                     NPYITSSDWGWAIDPTGLRYTLNRFYDRYQIPLFIVENGFGAVDTLEEDGKIHDLERIQ
                     YLKSHIEALEKAVTYDGVDLIGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMK
                     RYKKDSFEWYKNVIQTNGEEL"
     gene            complement(5278..7146)
                     /db_xref="GeneID:11241604"
                     /locus_tag="GYO_RS42585"
                     /old_locus_tag="GYO_4419"
     CDS             complement(5278..7146)
                     /EC_number="2.7.1.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /GO_process="GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241604"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145: Glucose-specific phosphotransferase enzyme IIA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003236458.1"
                     /locus_tag="GYO_RS42585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4419"
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="WP_014115812.1"
                     /transl_table=11
                     /translation="MSGKVRDYTRLAKDILEAVGGEENVIGASRCATRLRLVLKRSNPK
                     AKDIVKSMPGVITVVENSGQFQVVIGQHVGEVFEEFSKLVNIDLSGEQSENKGTMLNRI
                     IATMSAVFAPFVYILAAAGILQGALIIINLLFSGFEKTGVYQVFSFISWAPFTFLPIFI
                     AITASKHFKTNTYIAVACCAALVSPTWAEMAAQIADGKSISFLGIALSQTTYTSSVLPP
                     LFLVWMLSYVERFLNKRMNEVVRPLFVPFLCMVIMVPLTIVLIGPVTTLGANGIANGYN
                     FLAENVPALAGAIIGAFWQVIVIFGVHWGITPMVLANFDLYGRDSFQAYQTIAVIAQVG
                     AVLGVILKARNKETRKVSVSAGITGLFGITEPAIYGVTLRFKKPFIFGCISGAVGAIVA
                     SFFHPYYFAYAGLPGPLTIVNGINEQFPTSIWGILIGAAIAMILPVVLIQIFGYGEDTA
                     AQTEKENGQTAQANEETVYAPFSGKVIPLSNVPDEVFSSGAMGQGLAIEPSDNKLFAPF
                     DGTVVMVAPTKHAIGLRSASGVELLVHIGLDTVTLDGTPFTLKVKEGDTVKKGEVLVEF
                     DKAFIEEKGLTTITPVIITNSHAYQEILIEDLEESTIDQKLFTVVS"
     misc_feature    7164..7182
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.27"
                     /tool="antismash"
     gene            7303..8013
                     /db_xref="GeneID:11241605"
                     /locus_tag="GYO_RS42590"
                     /old_locus_tag="GYO_4420"
     CDS             7303..8013
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241605"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391893.1"
                     /locus_tag="GYO_RS42590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4420"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_014115813.1"
                     /transl_table=11
                     /translation="MLKYQQIAEEIETYIEEHDLQQGDKLPVLETLMAQFEVSKSTITK
                     SLDLLEQKGAIFQLRGSGIFVRKHKRKGYISLLSNQGFKKDLEDFNVTSKVIELDVRKP
                     TPEAAENLNIGIDVDIYYVKRVRYINGQTLCYEESYYNKSIVTYLNNEIVSHSIFHYIR
                     EGLGLKIGFSDLFLHVGQLNEEEAEYLGLEAGLPKLYIESIFHLTNGQPFDYSKISYNY
                     EQSQFVVQANSFLL"
     gene            8195..8358
                     /db_xref="GeneID:92812793"
                     /locus_tag="GYO_RS44210"
                     /pseudo=""
     CDS             8195..8358
                     /codon_start=1
                     /db_xref="GeneID:92812793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004393168.1"
                     /locus_tag="GYO_RS44210"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYKIIISTILTIPCPMDTITGFTRDEYCYESNELLHRFHWLLLYI
                     "
     gene            complement(8474..9196)
                     /db_xref="GeneID:11241607"
                     /locus_tag="GYO_RS42600"
                     /old_locus_tag="GYO_4422"
     CDS             complement(8474..9196)
                     /codon_start=1
                     /db_xref="GeneID:11241607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391894.1"
                     /locus_tag="GYO_RS42600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4422"
                     /product="peptide ABC transporter permease"
                     /protein_id="WP_014115815.1"
                     /transl_table=11
                     /translation="MKLEFKKSISNKVFIILGSMFAFLFLLGYFLLVGIDKVSHVTPEM
                     FFFSSYTVATQFGLMLFSFVIAFFINREYSNKNILFYKLIGENIYTFFYKKIAVLFLES
                     FAFIALGLLIISLMYHDFSHFTLLLFLFSAVILQYIFIIGTISMLCPNILISIGVSIVY
                     WMTSVILVAVSNKVFGFIAPFEAGNTMYPRIERVLQSDNMTLGNNDILYIILYLVSIMI
                     INAIILRFSKTRWIKMGI"
     gene            complement(9217..9846)
                     /db_xref="GeneID:11242218"
                     /locus_tag="GYO_RS42605"
                     /old_locus_tag="GYO_4423"
     CDS             complement(9217..9846)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11242218"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391895.1"
                     /locus_tag="GYO_RS42605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4423"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014115816.1"
                     /transl_table=11
                     /translation="MNIANYTLKVKGKTLLQDTDLHFSSGKINHVVGKNGVGKSQLAKD
                     FLLNNSKRIGRDIRQNVSLISSSSNIPNDVSKDFLLNFLSKKFDSEKINKIAHLLNLDN
                     IDGKVLIKNLSDGQKQKLKLLSFLLEDKNIIVLDEITNSLDKKTVIEIHGFLNKYIQEN
                     PEKIIINITHDLSDLKAIEGDYFIFTHQEIQQYHSVDKLIEVYINE"
     misc_feature    9851..9866
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.53"
                     /tool="antismash"
     gene            complement(10001..10759)
                     /db_xref="GeneID:11241608"
                     /locus_tag="GYO_RS42610"
                     /old_locus_tag="GYO_4424"
     CDS             complement(10001..10759)
                     /codon_start=1
                     /db_xref="GeneID:11241608"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: yydH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391896.2"
                     /locus_tag="GYO_RS42610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4424"
                     /product="hypothetical protein"
                     /protein_id="WP_014115817.1"
                     /sec_met_domain="yydH (E-value: 4e-149, bitscore: 494.7,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILKYEDEKYEVIVQKNVFIKDKTSGDYYKKNLDSLTDEQLSNF
                     KTYKEKVSSKFFYLFLSFTATMFMLNYIHLIKLQKELTTVIFGWGMWIIIAIYFIMNIV
                     LHELGHIYSLKFFGKNFDKVGFKLNFYVFPAFYVQLNETYMLSRNEKIIVHLFGLFINY
                     FIINILELINHFTISSEPLTVAFMLFSSTLLWNLVPILNSDGYKILLAFLGLDEYSRFK
                     TNHWLVLTIQIIGVGLAVNSVVHWILFIVN"
     gene            complement(10740..11699)
                     /db_xref="GeneID:11241609"
                     /locus_tag="GYO_RS42615"
                     /old_locus_tag="GYO_4425"
     CDS             complement(10740..11699)
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241609"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: TIGR04078"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391897.1"
                     /locus_tag="GYO_RS42615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4425"
                     /product="YydG family radical SAM peptide epimerase"
                     /protein_id="WP_014115818.1"
                     /sec_met_domain="TIGR04078 (E-value: 1.5e-166, bitscore:
                     551.3, seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.6e-06, bitscore: 25.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYDKTVSINLDSKCNASCDHCCFSSSPTSTIKMEKDYIRDLVTEF
                     AKNKTIQVISFTGGEIFLDYIFLKELMEIIKPYEKQITLISNGFWGVSRKRVQEYFYDM
                     NSLNVVALTISYDEYHAPFVKSSSIKNILEHSRKYPDIDISLNMAVTKDKMSNHILEEL
                     GDSILGVKITKFPMISVGAARTRIRQENIHKFYNLDDEDSLYCPGYEIVYHHDGEIYPC
                     CSPAIFETKITLREEYNQNFERTVEKLNSNLLLFILRKEGFKWFLDILKENNKIEEFDI
                     PYEFSSICGVCGSLFNSAEKINYFYPHMEKYYYENFEV"
     misc_feature    complement(11683..11701)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.76"
                     /tool="antismash"
     gene            complement(11757..11906)
                     /db_xref="GeneID:11241610"
                     /locus_tag="GYO_RS42620"
                     /old_locus_tag="GYO_4426"
     CDS             complement(11757..11906)
                     /codon_start=1
                     /db_xref="GeneID:11241610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614717.1"
                     /locus_tag="GYO_RS42620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4426"
                     /product="epipeptide YydF family RiPP"
                     /protein_id="WP_014115819.1"
                     /transl_table=11
                     /translation="MKKENTNNEPVKNLEFKGLLDESQKLAKVNDLWYFVKSKENRWIL
                     GSGH"
     misc_feature    12204..12221
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.05"
                     /tool="antismash"
     gene            12527..14452
                     /db_xref="GeneID:11241611"
                     /gene="fbp"
                     /locus_tag="GYO_RS42625"
                     /old_locus_tag="GYO_4427"
     CDS             12527..14452
                     /codon_start=1
                     /db_xref="GeneID:11241611"
                     /gene="fbp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391899.2"
                     /locus_tag="GYO_RS42625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4427"
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="WP_014115820.1"
                     /transl_table=11
                     /translation="MESKYLDLLAQKYDCEEKVVTEIINLKAILNLPKGTEHFVSDLHG
                     EYQAFQHVLRNGSGRVKEKIRDIFSGVIYDREIDELAALVYYPEDKLKLIKHDFDAKPA
                     LNEWYKETINRMIKLVSYCSSKYTRSKLRKALPAQFAYITEELLYKTEQAGNKEQYYSE
                     IIDQIIELGQADKLITGLAYSVQRLVVDHLHVVGDIYDRGPQPDRIMEELINYHSVDIQ
                     WGNHDVLWIGAYSGSKVCLANIIRICARYDNLDIIEDVYGINLRPLLNLAEKYYDDNPA
                     FRPKAAENRPEAEIKQITKIHQAIAMIQFKLESPIIKRRPNFNMEERLLLEKIDYDKNE
                     ITLHGKTYQLENTCFATVNPEQPDQLLEEEAEVIDKLLFSVQHSEKLGRHMNFMMKKGS
                     LYLKYNGNLLIHGCIPVDENGNMETMMIEDKPYAGRELLDVFERFLREAFAHPEETDDL
                     ATDMAWYLWTGEYSSLFGKRAMTTFERYFIKEKETHKEKKNPYYYLREDEATCRNILAE
                     FGLNPDHGHIINGHTPVKEIEGEDPIKANGKMIVIDGGFSKAYQSTTGIAGYTLLYNSY
                     GMQLVAHKHFNSKAEVLSTGTDVLTVKRLVDKELERKKVKETNVGEELLQEVAILESLR
                     EYRYMK"
     gene            complement(14724..16766)
                     /db_xref="GeneID:11241613"
                     /locus_tag="GYO_RS42630"
                     /old_locus_tag="GYO_4429"
     CDS             complement(14724..16766)
                     /codon_start=1
                     /db_xref="GeneID:11241613"
                     /inference="COORDINATES: protein motif:HMM:NF024573.5"
                     /locus_tag="GYO_RS42630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_4429"
                     /product="AAA family ATPase"
                     /protein_id="WP_014115822.1"
                     /transl_table=11
                     /translation="MILGVFINGFKSYAQTAYIHLCNNDTYKFTTIVGKNGTGKSAILE
                     ALNCYFKQGSWNTNRQSKNREDMFISPIFLIEKTSLEKWLKGSSEFKSKVEEITSGFER
                     VSTYLWEEADDSFKGATRRAYIKEFFNQIGKIKNKYSKSHYLLVSGRNVDSKSTSKPFS
                     TVIKELGSITLDQVNSVIDSYYNYIYIPVEQQAQSTLRIENIQMQKIMNQNVILKIEEL
                     LKERLKVDDKNQSLIDHINGQLSVFIEDINSIIKLVDSEYEFRARRNKKQNLTPSDIVD
                     NILQGYFSKRTLKSSQKEIEELSSGEQRRAMIDIIYAFLKNRGKEEEANGRNVILAIDE
                     PEVSQDLSHCFEQFERLEKLSNNFGNQVFVTTHWYGILPVIENGTLLHLSETEDSSYKN
                     KFSIFDFYNYLDSQEHFPDEIKLKSIYDLAISLSTYIRKESSKHLILCEGGTDKRYLET
                     LIDSSKVRILPVGGINNVRNLYNLLVMPLKIDKRVNSVKKVLCLTDTDPNITDNSDVGR
                     DPSGKIQLKRLQINHRENKVDLMSLDNFNPGAEYTVTRIEDVINPKIYKNVIQSVINEN
                     RDNFEDILFDEYELKENAIFSNLRGETNFLFCKTYEANQNKQNFISFIESKKTLLSFRY
                     VEEFNRALVTDGISSIPPVFISIKEFFKDDILKSYSIEPDKSTLH"
     misc_feature    complement(18429..18440)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.98"
                     /tool="antismash"
     misc_feature    complement(18501..18515)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 25.18"
                     /tool="antismash"
     misc_feature    complement(18957..18972)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.79"
                     /tool="antismash"
     misc_feature    19034..19054
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.85"
                     /tool="antismash"
     misc_feature    complement(20777..20790)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.57"
                     /tool="antismash"
     misc_feature    21053..21062
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
ORIGIN
        1 gaaagcagac gaagtcctgc aaaaacgtct ctacagtctg ccaaacgtca ctgtcgtgaa
       61 aaatgcacaa acaaaagaaa tcacaggcga tcagagcgtt aacggcatca catacgtaga
      121 ccgcgaaaca ggcgaagaaa aacacgttga actccaaggt gtattcgtcc aaatcggtct
      181 cgtgccaaac acagaatggt tagacggaac ggttgaacgg aacgacatcg gcgaaatcat
      241 cgtcgacaaa cacggtgcaa caagcgttcc aggcttattt gctgccggcg actgcacaga
      301 cagcgcgtac aaccaaatca ttatttcgat gggatcaggt gcaactgccg ctctcggcgc
      361 gtttgattac cttatccgta actaatacaa gaaagccgca atattgccag attggcagca
      421 ttgcggcttt tatattttgt aaaacagaat actttacata aactggtctg aatcaccaag
      481 gacatattaa gaaggcagta tttcttctaa acaatcttca ctgattttat aagattttgg
      541 tcttctgctc gtaagctcca caaatccttg ctcttctaaa taatccataa ctttattaac
      601 aatatgtctt gatttacctg atattttcat taactcttgc accgaaagca tgacatgatc
      661 atttacaaat acattaatag tgatgatgat atagaagagt tcacgttcat ccttataatc
      721 aacccattga tcacttttca tatagttttt aattcgatta agtttcatta aattgaattc
      781 aaggtcttca attatccctt tttgtcctga cagaagcaat tccagcatat tgattaaata
      841 aaaagtcatc tctcctcgat ttaaagggga gggaatttcc tctaaagctt tgtagtactt
      901 ttctttattc ttattcactg cgtaagaaaa cgtaatagct gaatactttt ccaaataact
      961 ggataaataa ctcccgacga ttagtcgtcc tgttctaccg ttaccatcat agaaaggatg
     1021 aatatattca taataataat gtgcaaccat ataacgataa agctgtggat gtgattcatc
     1081 atccaaataa tcaattaatg catccaatgc ttctgtaatt ttctgttcgg aactaatgcc
     1141 aatatgagta gttctatttc cgtcatttac ctcaacatat cctctcctaa aaagctctcc
     1201 atccggagca tcctctgcca cgatctcatc agctaccaat tcatcatata attttctgaa
     1261 gtcacgaaca ctcttaaaag aatcaatctg atctataaat tgatatgtct tcattagccc
     1321 tacaaatcgc ttatgttgtg gttcagattg ttctagcgca ttaagagctt ctttcaattc
     1381 tttttttgta cttcgaatcc cctcaatttc attattgctc tgtgcttcat taataattaa
     1441 tttattaaaa taaggtttaa caacaaattt aggtagttgt ctaattagtg aagagatttt
     1501 agaactattt aataacactt cattattcaa cttcatgagt tcatgggtat ttacataaaa
     1561 taattcgaat gaatcattag taagatgacc tttacggaat ccgcgtactg ttaatgatgt
     1621 agaatagctg ccatagctgc tttttctttt tatgaattcc ttatcatatg agtcagcatc
     1681 aattttataa aaaagttttg ataatttctc ataattcata ctatccatca cctctctaat
     1741 ttaaaattca tccctttttt aaattatata ctcattatag actcttttct aataaatatt
     1801 ctttattcct caaaataaat ctctctgttt gctgttagtc tgagaaaaga actaaattat
     1861 aatcaaagta ttgagtccta aacagatact ttgaacaaaa atggaataca ttccttcaaa
     1921 gatttgaaga aaaggggctg ccgttaaaaa caaggcagac ccctcaaatg aaatgaacca
     1981 acttgactga tggttgcaca aacaatacga atctttggga tcaggtgcaa ctgccgctct
     2041 cggcgcgttt gattacctta tccgcaacta atacaagaaa gccgcaatat tgccagattg
     2101 gcagcttgcg gctttctttt ttattccaaa aatattgcat gttttataca attgtaatat
     2161 agttgtaatg ttagtgaatg gtcacttcac actcagcata tttgctgttt ttaaagcgat
     2221 acgcactgat ttcctattta aagtgccctg atactttttg accttttttt tcagatcttt
     2281 aatggttttt tcctttttgg cattttctaa tgccataagc gcttcccagc gtttcgctgt
     2341 ttctgtggaa ctgcagccgc taactgtagt cacaggcgga agaaacttcg tgttagatag
     2401 tttttcgtca aaaggaacgg tatcaggaat cgctttctct tgataaatat gatccaattg
     2461 attttgattc aggaagctga tgaaatggtc aaagttttgc gcttgccgtt tctcaggctg
     2521 atgaaaatca agtgtttcaa ttaattctga cagttttgtc tgatctgtta tctcatttgc
     2581 catgacatgc gttaactgat ggtactcagc taattcccgc attcttgcat ctttcggaag
     2641 caaaaggctc ggtgttccgg caatcgttgc tgcgatattc ccatgcagcc ttgcgccaaa
     2701 gcttaaatca gcttgtctca ggaaatccag ccatgtcggc acatttaaaa agaaacggac
     2761 tctatcattc tgataagctg ggtcttccat gctgaccgga taattatcag caggcttcgc
     2821 tatcgcagga gcacctgcat acgtcagaat catctctttt cgccattgcg ggataaagta
     2881 atgattcggg aactctttca tgcttctcgt aatgaagtcc agtacatgct taggagacag
     2941 ccttgatgag ttaaccgtca ccattgaacc tggtgtaata tgggtttctc ttatcttcag
     3001 ttctcttcca aacgcataca tagaaggaca gccaattacc gtatggtcaa taccttcacg
     3061 gaatcctaat ctggaaaggt atttcgctgt gatttcaccg cggacaccga tcatatttga
     3121 tctctccagc acggcactca caaacgcctt cacatcttga tcaaaaggaa aaccctcatt
     3181 taattttggt tcaaacggag cacgcaaacc aaccccaatc acaacaaccg gaatggttag
     3241 tttcttaatt aattgggtat atttccgtaa agaaggtaca aaatcctcgc ggaatgcatc
     3301 tgccagcgga ataatataca tatcatatgt tttattaatt tgttcagcat ctgccggatt
     3361 aatccgataa taatctggtg taatcgtcgt ttcttctgtc atcagcgtac gaaacacact
     3421 gtaggcatat actaagtttc ctacgttgcc gccaatggag ttgcgaacaa tcatttcagc
     3481 tgcattgaat gtatcaaatg gggatatgcc agctcttatt aaaatgtttt tcaatgtgat
     3541 gttgcccctt cctcgccaaa tttttgtcag gagatttgct tagggaactc tatcataatc
     3601 ttaaaatctt cagccggaca cccgctttca tcccttttta ctcacaaact ccctcccttt
     3661 tttccgttct aatattaaat tatacaaaaa agcatcttac aggtgaaatc ataacatagc
     3721 aatcagcact ggtaatctat tcccatcatt ggatgtcagt tcatatcaca ccaaaaaacc
     3781 cgaatcaggc acttcagtaa aagtactcga ttcgggccag cagcttataa ttcctcgccg
     3841 ttcgtttgaa tgacgttttt gtaccactca aatgaatctt tcttatatcg cttcatggat
     3901 ccgtttcctt cattatcacg atcaacatag atcatgccgt agcgtttttt catttcccct
     3961 gttgtgaagg agacgatatc aataattccc cacggcgtgt agccaattaa atctacaccg
     4021 tcgtaagtaa ccgctttttc caatgcttca atatgtgatt tcaaatattg aattcgttcc
     4081 agatcatgaa tcttgccgtc ttcctccagc gtatccaccg cgccaaagcc gttttcaacg
     4141 atgaataacg ggatttggta ccggtcataa aaacggttta acgtatatct cagcccagtt
     4201 ggatcaattg cccaccccca gtcactcgat gtgatgtacg gattttcgac accattcggc
     4261 aagccgccgt tgacgatatc gcccgtatta tcattttcca catcgctttt cacagttgtg
     4321 gacatataat agctgaagcc taagtaatca acggttccgt ttcttaaaat ctcatcatcg
     4381 ccgtcttcaa atgtgatatg atagccttcc cgttcaaatt ccttcaacgc gtagcttgga
     4441 taataaccgc gaacctgcac atccgggaag aaatagcgct gtctcatttc ttcttcagcc
     4501 agcatcacat cttcaggatt ggaggagaaa ggataaatcg gcacgtgtga caccatggcc
     4561 ccaatctgga agtctggatt gatgtctttt ccttttgcca ctgctaaagc gctcgccact
     4621 aattcgtggt gcgccgtttg gtacatgact tccttggcgt tttcgttttc tccaaccacc
     4681 acacctgaat tcgtccatag gaacagcgga ttgttcacgt ccatttggtt gttgatctcg
     4741 ttaaatgtca tccagtactt cactttatct ttgtaacggt tgaagcaagc ctctgcgaag
     4801 ttgacgaaga agtccacgac tttccggttt ctgaagccgc catattctct tgccaaatgc
     4861 agcggcattt caaaatgaga cagggtaatg accggctcga tcccgtgctt cagcaattca
     4921 tcaaacacat catcatagaa ctgcaaaccc gcttcgttcg gttcagcctc atcgcctttc
     4981 ggaaaaatcc ggctccagcc gatggacgtc cgcaagcatt ttaatcccat ttctgcaaac
     5041 aaagcgatat cttccttgta tctgtgatag aaatcaatgg cttcatgatt cggataaaat
     5101 tcgttttctt caatagtgtc agtgattttt ctcggcacac cgtgcgcacc cgctgtcatg
     5161 acatcgacga cactcggccc tttaccgccc tgattccatc cgccttcaaa ttggtgggca
     5221 gctaaagcac cgccccataa aaaatccttc gtcatgtttc ccatgtttca ttcctcctca
     5281 gcttacgact gtaaataatt tttggtctat cgtactttct tcaagatcct caatgagaat
     5341 ttcctgatac gcatgtgaat tcgtgatgat gactggggta atcgttgtta accctttctc
     5401 ttcaatgaaa gctttatcaa attcaacaag cacttcgcct tttttgactg tatcgccctc
     5461 tttcaccttc aaggtaaaag gagtgccgtc taatgtcacc gtatccagtc cgatgtgcac
     5521 aagcaattcg acgccagacg ccgaacgaag gccgatcgca tgctttgtag gcgcgaccat
     5581 gacgacggtt ccgtcaaacg gggcaaacaa tttattatcg gatggctcaa tcgccaaccc
     5641 ttgtcccatt gcacctgaac tgaatacctc atcaggcacg ttagaaagcg ggatcacctt
     5701 gccgctaaac ggagcatata cggtttcttc atttgcctgt gccgtttgac cattttcctt
     5761 ttccgtctgt gcagcagtat cttcaccgta gccaaagatc tgaatcagca caacagggag
     5821 aatcatcgca atcgcagcac cgattaaaat gccccaaatg gatgtcggga attgttcatt
     5881 gataccattc acgatcgtca gcggtcccgg aagtcccgca taggcaaagt aatacggatg
     5941 aaagaagctt gccacgattg cgccaaccgc gccggatata cagccaaaga taaacggctt
     6001 cttaaatctc aaggttacac catagatcgc cggctctgta atgccaaaca gtcccgtgat
     6061 tccagcagag acgctgactt ttctcgtttc cttgtttctc gctttcaaaa tgacgccaag
     6121 cacggcccca acctgcgcaa tgaccgcaat cgtttgatat gcctggaatg aatctcgacc
     6181 gtataaatca aagtttgcca ataccatcgg cgtgatgccc caatgtacac cgaagatcac
     6241 gatgacctgc caaaaagcgc cgatgatcgc cccagccaaa gccggcacgt tttccgccaa
     6301 aaagttgtaa ccgtttgcaa ttccatttgc gcctaatgtt gtcacagggc caatgagaac
     6361 aatcgttaac ggcaccatga tgaccatgca tagaaacgga acaaacaacg gtctgaccac
     6421 ttcgttcatt ctcttattca agaatcgttc aacataagac aacatccaca ctaaaaataa
     6481 tggcggcagc acggaagacg tgtatgtcgt ttgcgataaa gcaatcccta agaaagaaat
     6541 gctctttccg tctgcaattt gagccgccat ctccgcccat gtcggactga ctaacgcggc
     6601 acagcacgct acagcgatat acgtgttggt cttaaaatgc tttgatgccg taatcgcgat
     6661 aaaaataggc aaaaacgtaa acggcgccca agatatgaaa ctgaaaacct gataaactcc
     6721 tgttttctca aaaccagaaa acaataagtt aatgataatt aatgcccctt gcaaaatacc
     6781 agcagcggcc agaatgtaca caaacggcgc aaacacagct gacatcgtcg caataatccg
     6841 gttcaacatc gttcctttat tctcgctctg ttcgccggaa agatcaatat tgaccagctt
     6901 agaaaattcc tcgaagactt cccctacatg ctgtccaatg acaacctgga attgaccgct
     6961 gttctctaca accgtaatga cgccgggcat cgacttcacg atatccttcg ctttagggtt
     7021 agatcgcttc agcaccaacc gaagcctagt agcacagcga gaagctccta ttacattctc
     7081 ttccccgcct acggcctcca aaatgtcttt cgctagtctt gtataatctc tcactttccc
     7141 cgacattttc acccacccct ttgtttggtt acgctttcat tataattgta ccggtataat
     7201 ttatcaatac ccaaacaaaa tatttgtata ctgactatga ttgtaagcgg tttatgctat
     7261 aattttgaca agtgaaacta aacgaataaa tgaggaatgc gtatgttaaa gtaccagcaa
     7321 atcgcagaag aaattgaaac atatatagaa gagcacgacc ttcagcaggg agataaactg
     7381 ccagtgctag aaaccctcat ggcccaattt gaagtcagca aaagcacaat cacaaagtcc
     7441 ctggatctat tagagcaaaa aggcgcaatc tttcagctca gaggaagcgg catcttcgtc
     7501 agaaaacata aacgaaaagg ctacatcagc cttctgtcaa atcaaggatt taaaaaagac
     7561 ctcgaggatt tcaatgtcac ctcaaaagtc attgagctgg acgtgagaaa gccgacaccg
     7621 gaagcggcag aaaacctaaa catcggaatt gacgtggaca tctactatgt caaaagggtc
     7681 cgctacatca acggccaaac cctttgctac gaagaatcct attacaacaa atccatcgtg
     7741 acgtatttaa acaacgaaat cgtctcccac tccatcttcc attacatcag ggaaggactg
     7801 ggattgaaga ttggtttttc tgatttgttt ctgcacgtgg gccagctgaa tgaggaggaa
     7861 gcggagtatt tggggttaga ggctggactg ccgaagctgt atatagaaag tatttttcat
     7921 ctgacgaatg ggcagccgtt tgattactcg aagatttcct ataattatga gcagtcacag
     7981 tttgtggtgc aggctaatag ttttttgctg tgacataacg attaaccgga aagcgaaaga
     8041 gaccaagaac aattgattct tggtcttttg atcaaagctg gaggccaaga tgccggacaa
     8101 ataagctgta cagtcagtac acaatcggtt agaaaatgta ttaagtgatg gtcggagccg
     8161 ttgtatcttg ttccaacaaa ggaagggaac agacatatac aaaatcatca tttctacaat
     8221 attaaccatc ccttgcccta tggatactat tacaggtttc actagagacg agtattgtta
     8281 tgaatccaat gaattacttc atcgttttca ttggctttta ctctatatat gagaatgttg
     8341 aaagaaaaac agcgatgaga tttggaaaag tccaatgcac gaaagcaaaa agaggcctct
     8401 ccttaacaaa attcatacac gtagccttta catagcataa aaaaagctac ttcccgagaa
     8461 gcagcttcct ttactaaatg cccattttga tccatctagt tttagaaaag cgaagtataa
     8521 tcgcatttat aatcatgatt gaaactaaat ataaaataat gtataaaata tcattattcc
     8581 caagtgtcat gttgtcagat tgtaatactc tttctatacg aggatacata gtattacctg
     8641 cctcaaatgg agcaataaaa ccaaacactt tattgcttac agctactaaa ataacagaag
     8701 tcatccaata aacgatgctt acccctatgc taattaatat atttggacat agcatgctta
     8761 tcgttccaat gatgaaaata tactgcagta taactgcaga aaataaaaac agtagtaatg
     8821 taaaatgtga aaaatcatgg tacatcaacg atatgattag cagacctagc gcgataaacg
     8881 caaaagattc caaaaataaa acagctatct tcttataaaa gaaggtatag atgttttccc
     8941 ctattaattt gtaaaagaga atatttttat ttgaatactc tctattaata aagaacgcta
     9001 taacaaatga aaataacatc aaaccaaact gggttgcaac agtataggag ctaaagaaaa
     9061 acatctcagg tgtaacatgg ctgactttat cgattccaac aagcaaaaaa taccccaata
     9121 aaaataaaaa tgcgaacatt gatcctaaaa taatgaaaac tttgttgcta atactttttt
     9181 taaactctaa tttcatctta agcccccact gttttattac tcatttatat acacttcaat
     9241 taatttatcc accgaatgat attgttggat ttcttggtga gtaaatataa aataatcccc
     9301 ttctatcgcc tttaaatcag acaaatcatg tgtaatatta atgataatct tctctgggtt
     9361 ctcctgaata tacttgttta agaagccatg aatctctata accgtttttt tgtctaatga
     9421 attcgttatt tcatctaaaa caataatatt tttatcctct agtaagaagc taagcagttt
     9481 taatttttgc ttttgtccat cactcaaatt cttaataagc actttaccgt cgatattatc
     9541 aagattaagt aaatgtgcaa tcttatttat cttttctgaa tcaaactttt tactcaaaaa
     9601 gtttaataaa aagtccttag aaacatcatt aggtatattc gacgagctag atattaaaga
     9661 tacattttga cgaatatctc tgccgattcg tttgctatta ttcaacaaaa agtctttagc
     9721 aagctgtgat ttaccgactc cattttttcc gacaacatgg ttgattttcc cactcgaaaa
     9781 atgtaagtca gtgtcctgaa gtaacgtttt gcccttcact tttaaagtat aattcgctat
     9841 gttcatatgc atacccctag gaaatattta cataaagaaa gagccgcttc tactttgtta
     9901 attggtaact actgttttca cttttgaggt acctctttca tttccgattc agcactggaa
     9961 gaaatgtttt tttcgatgat taatttggag atcttttact ctagtttaca ataaataata
    10021 tccaatgtac aacggaattt accgcaaggc caactcctat aatttgaata gtaaggacta
    10081 accaatgatt tgttttaaag cggctatatt cgtctaagcc aagaaaagcc aaaagaattt
    10141 tgtaaccatc agaattcaat attggaacta agttccacag taaagtagat gagaatagca
    10201 taaatgccac cgttaagggt tcactggaaa ttgtaaaatg atttattagt tctaaaatat
    10261 taattataaa ataattgata aacaagccga ataaatgaac tattatcttt tcatttctgg
    10321 atagcatgta ggtttcattc aattggacat aaaaagcagg aaacacataa aaattcagtt
    10381 taaatccaac tttgtcaaag ttttttccga aaaattttaa agaataaata tgtcccagtt
    10441 catgaagcac tatattcatt ataaagtaaa tagctataat tatccacatt ccccatccaa
    10501 atattacagt ggttaactct ttttgcaatt ttatcaaatg aatataattc aacatgaaca
    10561 ttgtagccgt aaaagataag aagaggtaaa aaaactttga tgacactttc tctttataag
    10621 ttttaaagtt tgataattgt tcatctgtaa gagaatctaa gtttttctta taataatctc
    10681 cacttgtttt atcttttata aaaacgtttt tttgtacaat cacttcatat ttttcatctt
    10741 catacttcaa aattttcata ataatatttt tccatgtgag gataaaagta gtttattttt
    10801 tccgcggagt tgaatagaga accacaaaca ccacaaatcg aagaaaattc ataaggtata
    10861 tcaaattcct ctattttatt gttttctttt aaaatatcca agaaccattt gaatccttct
    10921 ttcctaagaa taaataatag caaatttgaa tttaactttt ccactgttct ttcaaaattc
    10981 tgattatact cttctcttaa ggttattttt gtttcaaaaa tagcgggtga acaacacgga
    11041 taaatttctc cgtcatgatg atatacaatc tcatatccgg gacaatataa ggaatcctca
    11101 tcatcaagat tgtaaaactt atgtatattt tcttgtctaa tcctagttct ggcagcacca
    11161 actgatatca ttggaaattt tgtaatcttt acacctaaga ttgaatcacc taactcctcc
    11221 aaaatatggt ttgacatctt gtctttagta actgccatat taagggaaat atcgatatca
    11281 gggtattttc tgctatgttc taatatgttt ttaatactgg acgatttaac aaatggagca
    11341 tggtactcat cataacttat agttaaggct acgacattta acgaattcat atcataaaag
    11401 tattcttgaa cccttttcct gctgacaccc caaaacccat tagaaatcaa agttatttgt
    11461 ttttcatatg gtttaatgat ttccattagt tcttttaaaa atatataatc taaaaaaatt
    11521 tccccacctg taaaagaaat cacttgaatg gttttatttt ttgcaaattc agtaactaag
    11581 tctcttatat aatccttttc catcttaatt gtagaagttg gcgaactaga aaaacaacaa
    11641 tgatcacaag acgcattaca cttagaatct aaattgattg atactgtttt atcatacatg
    11701 attaaccccc ctgaaaaatg gtaaaggaga gttaaactct cctttatacc ccctaattaa
    11761 tgaccacttc caagaatcca gcgattttct tttgatttca caaagtacca aagatcattc
    11821 acttttgcta acttctgtga ttcgtctaat agacccttaa actctaagtt tttcacaggc
    11881 tcattgtttg tgttttcctt tttcataata tcccctcctt ctctactaat ataacccaat
    11941 tattccatat agtccaatat gagtcaacac attagactaa aaaatcagaa taattcttct
    12001 agttctagga tatatcactc attcgccatt gatatagatc cactgaaacc tatatcatat
    12061 agattaaaag tcatgtctca cctccgaatc aaaacatcat taaaagacta caacaggtat
    12121 acagatcttc aagaagatag aaacaaagac aacaattact cccattctta gttaatcaag
    12181 tagtgattag ggtaaacaaa tgattgttat cactatatta ataatgcaaa tttgataaca
    12241 agaataagga gctctgtccc tttcagccta accccggacc aaatagctct ctccgtgaag
    12301 actgttgtta aaggtttttt tgagctctcc tgctttctct ccttcttttc ttaattccac
    12361 gctcatctct gcacctctct cactcgtttc aattgtttct aaaagcagtt atgcggtact
    12421 atcatataaa ggtccaatgt tgaaaaacaa tgtcatactt ttaaattcac cttatcatgc
    12481 aaatgctcat aaataggggt ttattctaaa aaggggatgg acgattttgg aaagcaagta
    12541 cttagatcta ctcgcacaaa aatacgattg tgaagaaaaa gtagtaacag aaatcattaa
    12601 tttgaaagcg atactgaacc tgccaaaggg aactgagcat tttgtcagtg atttgcacgg
    12661 ggagtatcag gcattccagc acgtgctgcg taatggttca ggacgagtca aagagaagat
    12721 acgcgacatc ttcagcggtg tcatttacga tagagaaatc gatgaattag cagcattggt
    12781 ctattatccg gaagacaaac tgaagttaat caaacatgac tttgatgcga aaccagcatt
    12841 aaacgagtgg tataaagaaa cgattaatcg aatgattaag ctcgtttcat attgctcctc
    12901 caagtatacc cgctccaaat tacgcaaagc actgcctgcc cagtttgctt atattacgga
    12961 ggagctgcta tataaaacag aacaagctgg caacaaggag caatattact ccgaaatcat
    13021 tgatcagatc attgaacttg gccaagctga taagctgatc accggccttg cttacagcgt
    13081 tcagcgactg gtggtcgacc atctgcatgt tgtcggcgat atttacgacc gcggaccaca
    13141 gccggacagg attatggagg agctgatcaa ctaccattca gtcgatattc aatggggaaa
    13201 tcacgatgtc ctttggatcg gcgcctattc cggttccaaa gtgtgcctgg ccaatattat
    13261 ccgtatctgt gcccgctacg ataaccttga tattattgaa gacgtgtacg gcatcaacct
    13321 gagaccgctg ctgaacctgg ccgaaaaata ttatgacgat aatccagcat ttcgcccaaa
    13381 agcagccgaa aatagaccag aagcagagat taagcaaatc acaaaaatcc atcaagcgat
    13441 tgcgatgatc caattcaagc ttgagagccc gattatcaag agacggccga actttaacat
    13501 ggaggaacgg ctgttactag agaagattga ttatgataaa aatgaaatca cgctgcatgg
    13561 aaaaacatat cagctggaaa acacctgctt tgcgacagtg aatccggaac agccagatca
    13621 gctattagaa gaagaagcag aagtcataga caagctgcta ttctctgtcc agcattccga
    13681 aaagctgggc cgccatatga attttatgat gaaaaaaggc agcctttatt taaaatataa
    13741 cggcaacctg ttgattcacg gctgtattcc tgtcgacgaa aacggcaata tggaaacgat
    13801 gatgattgag gataaaccgt atgcgggccg tgagctactc gatgtatttg aacggttctt
    13861 aagagaagcg tttgcccatc cggaagaaac cgatgacctg gcgacagata tggcttggta
    13921 tttatggaca ggcgagtact cctccctctt cggaaaacgc gccatgacaa catttgagcg
    13981 gtatttcatc aaagagaagg aaacgcataa agagaagaaa aacccgtatt attatttacg
    14041 cgaagacgag gcaacctgcc gaaacatcct ggcagaattc ggcctcaatc cagatcatgg
    14101 ccatatcatc aacggccata cacccgtaaa agaaatcgaa ggagaagacc caatcaaagc
    14161 aaacggaaaa atgatcgtca tcgacggcgg cttctccaaa gcctatcaat ccacaacagg
    14221 catcgccggc tacacgctgc tatacaactc ctacggcatg cagctcgtcg cccataaaca
    14281 cttcaactcc aaggcagaag tcctaagcac cggaaccgac gtcttaacgg tgaaacgatt
    14341 agtggacaaa gagcttgagc ggaagaaagt gaaggaaacg aatgtgggtg aggagttgtt
    14401 gcaggaagtt gcgattttgg agagtttgcg ggagtatcgg tatatgaagt gagggatgtg
    14461 gggttcagag attattctct gggctctttt attaaatttc tcatttagta cagcaaattg
    14521 ataacaaggt ctgtttttct gctggttggc aattgcttaa atatcaataa aaatattgta
    14581 gatcgttatt ttttgaacaa aaaatttgaa aaaataatat atgatctgct ttcaaactaa
    14641 ctagtaaaga aaaaagccca tgtacttaaa acaacaatta catggactgt taaacagtga
    14701 ttttttctat tccttgttaa aagttaatgt aaggtagact tatcaggttc tatactataa
    14761 ctttttaata tatcgtcttt aaaaaactcc tttatactaa taaatacagg aggaattgat
    14821 gagattccat cagtgacaag tgccctatta aattcttcga catacctaaa agataagaga
    14881 gttttctttg attcgatgaa tgaaataaaa ttttgtttat tttggtttgc ctcatatgtt
    14941 ttacaaaaca aaaaatttgt ttctccccga agattactaa atattgcatt ttcttttaac
    15001 tcatactcat caaatagtat atcttcaaaa ttatctcgat tttcattgat tacggattgt
    15061 atgacattct tatatatttt agggttaatt acatcttcaa ttcttgtgac tgtatattct
    15121 gcaccaggat taaaattatc taagctcatt aaatctactt tattttccct atgattaatt
    15181 tgtaaacgtt tcaactgtat tttaccagag ggatctcttc caacatctga gttatcggtt
    15241 atattgggat ctgtatctgt taaacacaga accttcttta cgctatttac tcttttgtct
    15301 attttcaacg gcattactaa taaattgtac aggtttctaa cattgtttat tcctccaact
    15361 gggagaatcc ttactttaga tgaatctatt aaagtctcga gatatctttt atcagttccg
    15421 ccttcgcata aaattaagtg tttggaagat tcttttctaa tgtatgtcga tagacttata
    15481 gccaaatcat aaatgctttt aagtttaatt tcatccggaa aatgttcttg actatcgaga
    15541 taattataaa agtcaaaaat ggagaactta ttcttatagc tagagtcttc tgtttctgat
    15601 agatgcaaaa gagtcccgtt ttctatcact gggagaattc cataccagtg tgttgtgaca
    15661 aaaacttgat ttccaaaatt attagatagt ttttccaatc tttcaaattg ctcaaaacaa
    15721 tgagaaaggt cttgggatac ttctggctca tcaattgcca aaattacatt cctaccattt
    15781 gcttcttcct cttttcctcg attcttaagg aatgcgtata ttatgtctat cattgctcta
    15841 cgttgttccc cggaactcaa ttcttctatc tccttctgag aactttttaa cgttctctta
    15901 gaaaaatatc cttgcaatat gttatcaaca atatcagagg gagttagatt ttgcttttta
    15961 tttcttcttg ccctaaactc gtattctgag tctactaatt tgataatact atttatatcc
    16021 tcaataaaaa ctgataattg accatttata tgatctatta aggattggtt cttatcgtct
    16081 actttcaatc tctccttcaa gagttcctca atctttaata taacattctg attcattatt
    16141 ttttgcattt gtatgttttc aattcgtagt gttgactgag cttgctgttc tacgggaata
    16201 taaatataat tataatagct atcaataaca ctgtttacct gatctaacgt tattgatcct
    16261 aattctttta ttactgtaga gaaaggctta cttgtacttt tagaatcgac attcctacct
    16321 gatactaata agtaatgaga tttagaatat ttatttttaa ttttcccaat ctgattaaaa
    16381 aactctttaa tataagctct tcttgtagca cctttaaaag aatcatctgc ttcttcccaa
    16441 agatatgtac ttacacgttc aaagccagag gttatttcct ctacttttga tttgaattct
    16501 gaggagccct tcaaccattt ttctaaggat gttttctcta ttaaaaatat tggagaaata
    16561 aacatatctt ctctattttt actttgtcta ttagtattcc atgaaccctg tttgaaatag
    16621 caatttaatg cctcaaggat tgcacttttt cctgttccat ttttaccaac aatggttgta
    16681 aatttatagg tatcattgtt acacaagtgt atatatgctg tttgagcata tgatttaaac
    16741 ccattaataa acacacccag aatcatttga ttaccatcct cctagttaga attatctaat
    16801 cttatataag attaatattg aaataaacgg aaaatagctt aaatctcaca cactttctat
    16861 aatttttaca tagtgtataa acctcccgca cttattataa ggctctccgt actatatcta
    16921 aatgagaaaa cactcaactt aaacacctaa tattaaagtg aaatgaactt ttatgtaaat
    16981 tcaggtgaca agtcgtacta agaattattt agagagccag acaataatat caggctcctg
    17041 aaattattag catttctaaa agttattaca aaatattttc tctaagcata taaccagcaa
    17101 ctgatccttt ctcaactaaa aagtctaata tgaccagtac ttctcgtttt aattttgtta
    17161 ctcttcttat cctctcacgg ttttgataaa tataactcct cattagattt tctaaataat
    17221 aaattgtata ttcctttaac ttattttgtc gtatctttgg atactcaatt aagatcttag
    17281 aaatccaagt aattccatca gaaagatatc tatgtccaat tccattcaat agctttgcta
    17341 ttgagtataa aacagcagaa gattctcccg tatttcttgc tactttatta aaaaactttt
    17401 tattaccctc tttaaaagta tcccattcag taacattttc attccacggt gatcgggcaa
    17461 acaggtagct ctcaataata tcttgattgt aatagctgtg accttcactc ttgcataaac
    17521 cagttacttt gtcataaaac atttcccata ctaaccaaaa attatcatat gtttttaata
    17581 tatcttcagc cacaatgaat tctttgaata aatcggctaa tgattcattg ctactaaaac
    17641 cttcaataaa tggttttaga tactcagaaa tattatttct tggagaagtt aaaacaattc
    17701 taacgaactt acttaagaaa ttatgactta attgataatc aactttttct tctctatcat
    17761 tagataatag tttctctgca aaaaccgata caatttcttg agtaattatt ttatgagatt
    17821 catcaaaaat atttaaagga attaattgaa atgcttttcc aagtgtaatt aaacttatat
    17881 tttttatatt ttttatatca tccaaagtaa tagagtttgc aataatcctc tcaatctctt
    17941 tttcataatt aattacaaac ttttcgatta tatccctctg atacaattgt tggttgtttt
    18001 tattataatt ttcttgccgc acttcttctt gcatcacatc aaacttcggt tttaaatata
    18061 aaaaaccaag tagtaaagat tgagcatcat caaaatttat actccataaa ttattataaa
    18121 tcgtattcgc tgagtaatca gagaatttag cgttcattcc catcggatga gaatcgcaca
    18181 aagttaatag tagaatcgct tttatatttt ctttttctaa aggaaatttt tctaacataa
    18241 aaggcaaaac agaaatcgct gattcaacgc catctcctat ttgataagaa taattggaca
    18301 caaaagagga agatgaaatt gtcaatatta tatctttaca tagctccttc tcaatttctg
    18361 ttaattcgtc aaaatattct tttatcatta cagcgcatac cagaggtgga attgatttat
    18421 aaaaaaaaga aaactctttc ctattcccct taaaaattcc gataatttcc tcaacttcct
    18481 ttaatgcacg tttggggttc ttttcatatt gagtatagac tttataattt tcatcacttt
    18541 ttaatttgta ctctgcccat attcttaatg aagtatactt cattgcttta gaactttctt
    18601 gaagagaaga ttcactatat tcctttaaat caggcgcaat ttctggattg aaatttatct
    18661 gtaatccctc atctactttt tcaactgtag gattcatttt tcttctatcc attctagcaa
    18721 gataaagtct ccaagtatta tgatcttcca tggagtcgtt tttaagctcc tcataatatt
    18781 tatcaaaaat agaccatata gtcttttgtc ttttttctac ttcttcatct gttacacttt
    18841 ctcccttgaa aaattggtac gataagcaaa gatgctcgag tgtttttttt ctatgaccca
    18901 tattgtaaga gttcattctt tcttcttcat gaattttatt ctctgttatt atcccagtga
    18961 aaaaatgttg aaattttaac gattgctctg acagcattct acgtgtttca tataaaaaaa
    19021 attctttcgt ttgaaataaa actttggcta cgttgaaagt tttctccgga taagctaaaa
    19081 ctatactcaa tactattgct gttatagaag cagaagtaga atttctgatt aagtataaaa
    19141 gattactttc caatatttta gaatcagcgt tctttgctgt ttcaagaagg aacttttcta
    19201 atgccatatg aattgattga aaaatatcag gtgaattatg attaccccta tatgtgtccc
    19261 aaagtctggt atttatatac tgtcttacta gcagagagtc ggtaacaacc tctacttctt
    19321 caacttctga ttcatctaaa tttaatttca cataacattc aactgatctg tttataaatt
    19381 ttagtaagaa atcgatggtt tctttatgtg aataatgaag caaccagtaa ataggtgttt
    19441 gatatgcact tggaggataa tagttcctgt gattctcatc aatacagaaa tcatcttcaa
    19501 cgccaacact ataatgaaat ggacgacgtt tttcttgagg gttaaaccaa tataaatccg
    19561 ctagcctcag tatatattca gggagtgctt taagaacttc ctggttttca cccgttttcg
    19621 ataaaatagt atttaccaag ttataataag gatctctata atttttccac tcatttttta
    19681 ttacctcgtc aaaaacggtg atgagttcct ccgttatttc agcagctcca tttaaaattg
    19741 tttggataag tcttttctca atatcttctt ctctcgaaag gtaaatgtct ttttcaacga
    19801 tttcttgata atgtcttaaa gcaattaaag ctgctaactt tgttgtttga ccacttttaa
    19861 ctttattatt ccattcattt attatcggca ataagaagtt aagttgctct aattcaaatt
    19921 cattttgatt tttgtaaatt aactttatga tgctttccca gccttttcct ttaggctttg
    19981 taaatatata tttcatatag gaaatggagt atttatccaa acctactttt tttaaaagac
    20041 attcatcaac ttctttacac cctatacgca ataaaaacgt tactcgtttt aatagttttt
    20101 ggttattctc aagtaacttt tcctcgaaca tatcaacaaa gtgatcagaa tatggtgaca
    20161 ataacattga taccaaaact tcatctttcc aaaaatagga tatgtcttca tcttctatta
    20221 catcttctat aaaactctta attgaattat cttcacttag aagcttttct gatacccatt
    20281 tccttaaact tcgacgaacg ggcagagatt ctccaatttt cgtgaaaaaa tcataatagt
    20341 tctcttgcct gataaattca acttctatca gtttttccaa agcccactct tcataaatat
    20401 cgtgagtaat aaagtatcct gctgtttcat atcccaagat accatcttgt actaaagaac
    20461 taatagcgga gtcactataa ttagttgaaa caaaaaattg accttcactt gctctttgaa
    20521 aagcaatctt cataaaacat tgctctctgt ttggttttga cttttttatt gttttattcc
    20581 atagtttctc tttaaagttt ttgtaatcaa ttacttcgtc tttactataa aatttcaagt
    20641 attcatttaa ataaaaaatg tttttaagta actccaacaa ttttgtatca gttggcaaat
    20701 taaaattata agcttgagag tttgctatca gttcttccat gctcagagtc tcaatataaa
    20761 atttaacagg tttcacttga tattggtcaa taaactgcat atctaaatca gacagataat
    20821 tgcttctcgc tgtaaatata attttccatt tattttttag tagtacagag agaaattctt
    20881 tgaatggatc tgtattttcc agatccaaca acttttcagc cgaatcaatt acaattagtt
    20941 ttttctcttc tttatggact tcagtaaagt cctgcaaact atacccacca aataagttat
    21001 ctatattatt tgtttcaaac tcactggcct taaaaatata aataggaata tttgtttttt
    21061 gatcctcata taaccttttt atgactgcag tttttccaac tccacctaaa ccagttacca
    21121 tcaatacgtg ctcattttca attgcgctta atatcccatc aagaaaatta tctctatcaa
    21181 tttctatttt cttcccttgg tagttcatgg atgtttgaat gttctctaag attgtttcgg
    21241 catgagcttg tttttccgat aaaagttgaa cgatactctt ttcaaaacta aagaaatgtc
    21301 ggaccattaa ttcgtttttc acggtaacaa aaggtgactc aaagaaactt gctgtcctcc
    21361 attcaatttg gagatcaagt tccctagcct tattttcaat atctactttt gcttgaggat
    21421 cgttttgttc aggattacga ggattatgac tttgacccca ttctccgttt gtataaaaga
    21481 taattttgct taaatctgta tagtctcttt tacttttaat caaagtacta atcaagtcgc
    21541 ttttatgatc cgataaagtt gtttcataaa atttcgcttg ccatcctata acatcttttt
    21601 ctacagaaat tggattggtt tcaataccag attgattttt atatctaaaa ataccaaact
    21661 cttttccaaa ctcttcacaa aataaaagat agcaaagcc
//
