LOCUS       NC_016047              20747 bp    DNA     circular CON 13-SEP-2024
DEFINITION  Bacillus spizizenii TU-B-10, complete sequence.
ACCESSION   NC_016047
VERSION     NC_016047.1
KEYWORDS    RefSeq.
SOURCE      Bacillus spizizenii TU-B-10
  ORGANISM  Bacillus spizizenii TU-B-10
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M.J., Rasko,D.A.,
            Daugherty,S., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Whole-genome sequences of Bacillus subtilis and close relatives
  JOURNAL   J Bacteriol 194 (9), 2378-2379 (2012)
   PUBMED   22493193
REFERENCE   2  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M., Rasko,D.A.,
            Daugherty,S.C., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2011) Institute for Genome Sciences, University of
            Maryland School of Medicine, 801 W. Baltimore St, Baltimore, MD
            21201, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000227465.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 01:46:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,304
            CDSs (total)                      :: 4,177
            Genes (coding)                    :: 4,051
            CDSs (with protein)               :: 4,051
            Genes (RNA)                       :: 127
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 90 of 126
            Pseudo Genes (incomplete)         :: 52 of 126
            Pseudo Genes (internal stop)      :: 16 of 126
            Pseudo Genes (multiple problems)  :: 28 of 126
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:59:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3550888
            Orig. end                         :: 3571635
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002905.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="9"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(424..1356)
                     /db_xref="GeneID:11241104"
                     /gene="hprK"
                     /locus_tag="GYO_RS39830"
                     /old_locus_tag="GYO_3837"
     CDS             complement(424..1356)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241104"
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="GYO_RS39830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3837"
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_014115306.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGVNRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEDKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDSEQDE"
     misc_feature    1468..1483
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            1538..2728
                     /db_xref="GeneID:11241105"
                     /gene="nagA"
                     /locus_tag="GYO_RS39835"
                     /old_locus_tag="GYO_3838"
     CDS             1538..2728
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241105"
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="GYO_RS39835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3838"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_014115307.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.5e-40, bitscore:
                     137.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESLLIKGIAIVTENEVIKNGYVGINEGKISTISTERPKESYSK
                     EIQAPADSVLLPGMIDIHIHGGYGADTMDSSFSALDTMSSRLPEEGTTSFLATTITQEH
                     GHISQALVNAKDWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVALFKK
                     WQQEAGGLIKIVTLAPEEDQHFELIRYLKDESIIASMGHTDADSALLSEAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFMAELIADGIHSHPLAAKLAFLAKGSTKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGKTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTEGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     gene            2725..3453
                     /db_xref="GeneID:11241106"
                     /gene="nagB"
                     /locus_tag="GYO_RS39840"
                     /old_locus_tag="GYO_3839"
     CDS             2725..3453
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241106"
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="GYO_RS39840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3839"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_014115308.1"
                     /transl_table=11
                     /translation="MKVIECQTYEELSQKAAKIAADTIKEKPDAVLGLATGGTPEGTYR
                     ELIRLHQTENLSFQNVTTVNLDEYAGLSSDDPNSYHFYMNHRFFQHIDSLPNRHFIPNG
                     NADDLEAECRRYEQVVESLGGTDIQLLGIGRNGHIGFNEPGTPFKSRTHVVTLNEQTRQ
                     ANARYFPSIDSVPKKALTMGIQTILTSKRILLLISGKSKAEAVKKLLEGDISEDFPASA
                     LHLHSDVTVLIDREAAALRP"
     gene            3471..4202
                     /db_xref="GeneID:11241107"
                     /locus_tag="GYO_RS39845"
                     /old_locus_tag="GYO_3840"
     CDS             3471..4202
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241107"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="GYO_RS39845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3840"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_014115309.1"
                     /transl_table=11
                     /translation="MKIDKQSPIPIYYQIMEQLKAQIKSGELLPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGFLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYKLIDSTEGLAAILGCGHPSPIHQVTRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYEHIERYNSIPISSAKQELEPSAATSQEASILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(4221..8090)
                     /db_xref="GeneID:11241108"
                     /locus_tag="GYO_RS39850"
                     /old_locus_tag="GYO_3841"
     CDS             complement(4221..8090)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="GYO_RS39850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3841"
                     /product="metallophosphoesterase"
                     /protein_id="WP_014115310.1"
                     /transl_table=11
                     /translation="MRKYTVIASLFLSFLSVLSGGHHEPKAFPVINQEPFQTPHYIPLL
                     ENPPQIDVKAEMKSNLMIEAQVRDNEYQAFSAFLFYKQSNELGYKMVPMDPTPGAVRKF
                     FAQIPKRLIWNSELEYYIVVSNGKQRVESEMKKLKLEGYQADLAHIPELLITELAVDTK
                     NIGRADGYEFIEIYNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPEKKITIPSGETFVF
                     WLKPAGHPELTAEDFNRYYQTQLTEGKNLAVIEETEGMANTRPRAAVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPMDGTAELLNISIGEKNPSPGTVLQAQVPEQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRIFAEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVTAGDGINEARTPVKMIDIKQTSKSHGLRMNIENRDTLSGTQ
                     FLKATTDGRTDSIRLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPETLLRKGKQLQHITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTSKLSEGVHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSKIEEVKASLDGESI
                     TLPYHTSSSELLPGKHSLKVTATDLAGNKTVIERTFKTEREHPDQPEVIDSEADTHRAK
                     LSVRVKDPTNDAMDVAFYRGFQYTARNNVKIFKHASLTEPPKSFVPESETPFTNKELER
                     VSAADGKTVSTEKKELFPYHRFEVAVDPSVDENDLAEAVWKGSSLPGRKVTMYVWNYRT
                     NEWQPVDSFVAKNDKPFMLKASVIASDFVRKSKMNVIVQDEIPPAKDMYTFVWMSDTQY
                     YAESYPHIFDKQTAWIKDNQKQLNIKYVFHTGDIVDDSADIRQWKNANRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITNEDIAWMNQVLKKHPDRMAVLAFHEYLLVSGNRSPIGEKIFKKVVKTNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPHLQDKNYYDADTHGDKDEFSLSLDLKPRIKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDHLEPHSVYYWYIIVEDSFNGKTKSPIWKFKTKKETYRPAPDQLDFR
                     HVSNP"
     gene            8255..8728
                     /db_xref="GeneID:11241109"
                     /locus_tag="GYO_RS39855"
                     /old_locus_tag="GYO_3842"
     CDS             8255..8728
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11241109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="GYO_RS39855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3842"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_014115311.1"
                     /transl_table=11
                     /translation="MDNSIHDELIQAIQQFALKRDKRVMQKVQIPSRDMSSEHLEHLRK
                     EWTLTQLHIVSCIHTSQNVNNSFLASRLHISKAAVSKAVQALLKHNIITVTKKPGNKKE
                     IFYTLTESGRELAALHEQLHEKAKEQYKQLFNEFSIDDLKTVTAFFNLWVKHM"
     gene            complement(8769..9986)
                     /db_xref="GeneID:11241110"
                     /gene="cypX"
                     /locus_tag="GYO_RS39860"
                     /old_locus_tag="GYO_3843"
     CDS             complement(8769..9986)
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /db_xref="GeneID:11241110"
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391386.1"
                     /locus_tag="GYO_RS39860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3843"
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_014115312.1"
                     /sec_met_domain="p450 (E-value: 2.8e-35, bitscore: 119.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQSIKLFSVLSDQFQENPYAYFSQLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVQRAEPVMRGPVLAQMHGKEHSAKRRIVVRSFVGDALDHL
                     SPLIKQNAENLLAPYLERGRIDLVNDFGKTFAVCVTMDMLGLDKRDHEKIAEWHSGVAD
                     FITSISQTPEARAHSLWCSEQLSQYLMPVIEERRVNPGSDLISILCTSEYEGMAMSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFERPDVFYIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKTEIEIVANIVLDKMRNIRLEEGFRYAESGLYTRGPVSLH
                     VAFDRA"
     gene            complement(10001..10747)
                     /db_xref="GeneID:11241111"
                     /gene="pchC"
                     /locus_tag="GYO_RS39865"
                     /old_locus_tag="GYO_3844"
     CDS             complement(10001..10747)
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /db_xref="GeneID:11241111"
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="GYO_RS39865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3844"
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_014115313.1"
                     /sec_met_domain="CDPS (E-value: 1e-82, bitscore: 275.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEMATERKPIDFTAEPLTQNCREIFERRQHVLVGISPFNSRFSE
                     DYIYRLIGWATAEFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     AAHGGDTKAIHTFSDFTENKAYQLMRQEVEHAFFEQPHFRHACLDMSHEAIIGRARGIS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSIR
                     MRPNQGYLIVQEMAQMLSETRITSEG"
     gene            11186..11695
                     /db_xref="GeneID:11241113"
                     /gene="pchR"
                     /locus_tag="GYO_RS39870"
                     /old_locus_tag="GYO_3846"
     CDS             11186..11695
                     /codon_start=1
                     /db_xref="GeneID:11241113"
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="GYO_RS39870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3846"
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_014115315.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVIDIPK
                     NMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVY
                     FKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQDEQNAVLKFLEQLTSTLEAEQNDET
                     PDKPVK"
     gene            11717..12928
                     /db_xref="GeneID:11241114"
                     /locus_tag="GYO_RS39875"
                     /old_locus_tag="GYO_3847"
     CDS             11717..12928
                     /codon_start=1
                     /db_xref="GeneID:11241114"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="GYO_RS39875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3847"
                     /product="MFS transporter"
                     /protein_id="WP_014115316.1"
                     /transl_table=11
                     /translation="MTQTKSKAVLILYIVCFSAFFASLSQNIYSPIIPIIKESFHVSAA
                     MVNLSVSVFMIVTAIMQIILGTIIDFKGERFVLIAGIMATAAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGSDRGSAMGTYQMLLSAAPAIAPVLGGFIGGAAGY
                     EGIFWMLTAISVVMLVTNSIIFPKDSPAGSKQQAQGNVFAHYKSIFTNRTGNVILTLSF
                     VLFFIYFAVIVYLPILLTEHYHIDVSIAGLLYLPLALSTIAGTFLFKKIQAKIALSTLF
                     IGSNVIAACSIMLFAVTHSVSLILMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GVFNFIRYTGMAAGPMISAYLLTLMPSAMSFGLLGLIFAALSFCLLPQMYPPQKRVKQK
                     KHHM"
     gene            complement(12959..13318)
                     /db_xref="GeneID:11242145"
                     /locus_tag="GYO_RS39880"
                     /old_locus_tag="GYO_3848"
     CDS             complement(12959..13318)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11242145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391390.1"
                     /locus_tag="GYO_RS39880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3848"
                     /product="phage holin family protein"
                     /protein_id="WP_003219771.1"
                     /transl_table=11
                     /translation="MVKWAVSILVNALLLIVIDGYIDSIHVSSIGAAIIASLILSILNV
                     LIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILSVF
                     HLLIQKGILEPLRKK"
     gene            complement(13320..13517)
                     /db_xref="GeneID:11241115"
                     /locus_tag="GYO_RS39885"
                     /old_locus_tag="GYO_3849"
     CDS             complement(13320..13517)
                     /codon_start=1
                     /db_xref="GeneID:11241115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391391.1"
                     /locus_tag="GYO_RS39885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3849"
                     /product="PspC domain-containing protein"
                     /protein_id="WP_014115317.1"
                     /transl_table=11
                     /translation="MNRLYRSEKNKKMAGVIGGLAEYFNWDASLLRVITVILAIMTSVF
                     PVLLIYIIWIFIVPSERDMK"
     gene            complement(13522..14619)
                     /db_xref="GeneID:11241116"
                     /locus_tag="GYO_RS39890"
                     /old_locus_tag="GYO_3850"
     CDS             complement(13522..14619)
                     /codon_start=1
                     /db_xref="GeneID:11241116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391392.1"
                     /locus_tag="GYO_RS39890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3850"
                     /product="DUF4097 domain-containing protein"
                     /protein_id="WP_014115318.1"
                     /transl_table=11
                     /translation="MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSV
                     HVHDEEEPFTAEKKESSKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKD
                     TDFSSVELQIANGSVNIVPWEDEDIRAECQAKVYRADSQDAARHAFLQHIECEIKGNKF
                     FIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSHLT
                     AEKATAETANGQIKLASHSCGTIEAETINGLIDLRGRSESIDVQSFNGNIAIHVTDSDC
                     RSIYTKTTTGNVELSIPDDLAVKAELKSNLGSLSHELMDVEMLKEKNDTIQKEMLFTSN
                     QAHDQNITVFSESLTGTIKLKYSQR"
     gene            complement(14644..14970)
                     /db_xref="GeneID:11241117"
                     /gene="yvlA"
                     /locus_tag="GYO_RS39895"
                     /old_locus_tag="GYO_3851"
     CDS             complement(14644..14970)
                     /codon_start=1
                     /db_xref="GeneID:11241117"
                     /gene="yvlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391393.1"
                     /locus_tag="GYO_RS39895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3851"
                     /product="protein YvlA"
                     /protein_id="WP_003219765.1"
                     /transl_table=11
                     /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVDEKETKRHAIRSLI
                     SHIVPFAGWLVLFIAFLGGAIAIDGDSLLPVFVIIGGAVIYFLVVIGIMIWNVIQGIKV
                     LRAA"
     gene            15190..15420
                     /db_xref="GeneID:11241118"
                     /locus_tag="GYO_RS39900"
                     /old_locus_tag="GYO_3852"
     CDS             15190..15420
                     /codon_start=1
                     /db_xref="GeneID:11241118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391394.1"
                     /locus_tag="GYO_RS39900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3852"
                     /product="hypothetical protein"
                     /protein_id="WP_003219764.1"
                     /transl_table=11
                     /translation="MEKDPSDYTVTQESVLKLIREQKRMNREMIAELEQIHGPLPISHD
                     IQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL"
     misc_feature    complement(15206..15221)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(15619..16443)
                     /db_xref="GeneID:11242146"
                     /gene="hag"
                     /locus_tag="GYO_RS39905"
                     /old_locus_tag="GYO_3853"
     CDS             complement(15619..16443)
                     /codon_start=1
                     /db_xref="GeneID:11242146"
                     /gene="hag"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391416.1"
                     /locus_tag="GYO_RS39905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3853"
                     /product="flagellin Hag"
                     /protein_id="WP_014115319.1"
                     /transl_table=11
                     /translation="MRINHNIAALNTLNRLSSNNGAAQKNMEKLSSGLRINRAGDDAAG
                     LAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRMRELTVQAGNTGTQQ
                     AEDLGAIKDEMDALIEEIDGISNRTEFNGKKLLDGTETDGFTFQIGANAGQQLTVNIDS
                     MSANALGVDTLNVKDFATTPFDTQLESIDTAINNVSKQRAKLGAVQNRLEHTINNLGAS
                     SENLTAAESRIRDVDMAKEMSEFTKNNILSQASQAMLAQANQQPQNVLQLLR"
     gene            complement(16796..19669)
                     /db_xref="GeneID:11242147"
                     /gene="uvrA"
                     /locus_tag="GYO_RS39910"
                     /old_locus_tag="GYO_3854"
     CDS             complement(16796..19669)
                     /EC_number="3.1.25.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11242147"
                     /gene="uvrA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391396.1"
                     /locus_tag="GYO_RS39910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_3854"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_014115320.1"
                     /transl_table=11
                     /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGRKGA
                     HVKVLDQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAARLSDS
                     LETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGACPTCDG
                     LGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDVPVKDLP
                     QHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDFIREQMEQ
                     YMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITEQSVADALAFFKGLTLSEKDMQIANL
                     ILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGVLYILDEPSI
                     GLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGIHGGQVMAAGT
                     PEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGAAENNLKKVNAKFPLGTFT
                     AVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDKVIDIDQAPIGRT
                     PRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFFENIPKIKRKLQTLF
                     DVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDEPTTGLHVDDIARLLV
                     VLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIVASGTPEEITEVEESYT
                     GRYLKPVMERDKKRMTSLLEAKETATS"
ORIGIN
        1 cggccgatcg cctggccgag taaaatgctt ggcgcggcaa tatccgcaag cttccagaac
       61 gaaaggtttt tcactctcga aaacacataa cctgttaaaa tggcgccgat caatccgccg
      121 tgaatggcaa tgccgccttt ccaaatctta atgatttctc cgggatgtgc cgcataataa
      181 tcccattcaa atgcaacgta ataaattcgt gcgcaaataa tcgcaatcgg aatggcaaac
      241 aggacaagat cgataaacgt atctttctgc agcccccgtt tctcactttc cctcatcgca
      301 atccaaagcc caagcaaagc gccgagaccg ataatgattc cgtaccaatg gacggccaac
      361 ggccctagct gaaacgctat cggattaagt ggttctatcg cttcattcat ttaacgccaa
      421 ctcctattcg tcttgttcac tgtcttcaat gacatccgcc agcttattgg taaattgctc
      481 agcggcgttc agccccatcc gcttcaatct gaagttcatt gctgccactt cgatgatgac
      541 tgcgagattt cggcccggac ggacaggaat cgtcagtttt gtaatttctg tatcaatgat
      601 tttcatggtt tcttcctcaa gcccgagacg gtcgtattgc ttgccctgct cccaaagttc
      661 aagattcatg acaatcgtaa tccgtttatt gcttctgacc gcaccggcac caaacagcgt
      721 catcacgttg ataatgccaa gccctctgat ttcaaggaga tgctcaatta attcaggagc
      781 gtttccgaca agggtatcct gatcttcctg ccgaatttca acacaatcat cggcgacaag
      841 gcggtgcccc cttttcacaa gctccagcgc ggtttcactt ttcccgacgc cgctctttcc
      901 tgtgatcaat acgccgacac cgtatatatc cacaagcaca ccgtgaatgg ctgtggttgg
      961 cgcaagtctg ctctcaagga agttggtcaa ccggcttgac agccttgtcg ttttcagcgg
     1021 cgatctgagg acaggcacgc cgtttttctc agaagcgtca atcagctcct gcgggatagg
     1081 catatctcta gaaagaataa tagctggtgt tacatccgtg cacagagaat ccattcgctg
     1141 ctttttatcc tcttccggca gctgttcaaa gaaagaaagc tccgtttttc cgagaagctg
     1201 cacgcgctct ctcgggtaat atgtaaaata tccggcaatt tcaatgcctg gtcttgataa
     1261 gtcactcatt gtaatcgggc ggttaactcc ttcttctccg ctgattaatt ccaaattgaa
     1321 ctgttccatt acgtcttttg tgcgaacctt tgccacgata tgttcctcct gttccgggct
     1381 gccccgagct tgctcacaat aatttcattt tatcactttc gggcttgaac ctaaaacaga
     1441 ttttataaaa gacaggaaaa cgccttagct ggtctagatc actagtctga aaaggggtaa
     1501 aataaatgta ttcatattcc agaaaggcgg atcacctatg gcagaaagtc ttcttatcaa
     1561 aggcatcgcg atcgtgacag aaaacgaagt aatcaaaaat ggctatgtcg gaatcaatga
     1621 aggaaaaatc agcacaatct caacagaacg tcctaaagag tcttattcaa aagagattca
     1681 agcaccggca gattccgttt tgcttcccgg gatgattgac attcatattc acggcggcta
     1741 tggcgcagat acaatggatt caagcttttc agccctcgac accatgtcgt caaggctgcc
     1801 cgaagaaggc acgacgagct ttttggcaac aacgattact caggaacatg ggcacatttc
     1861 tcaagctttg gtaaatgcaa aagattggaa agcagctgag gaatcctctt tattaggtgc
     1921 ggaactgctc ggcattcatt tagagggccc ctttgtttca cctaaaagag ccggggcgca
     1981 gccaaaggaa tggatcaggc cttcggatgt tgcgcttttc aaaaagtggc agcaggaggc
     2041 gggcggactg atcaaaattg tcacactcgc gcccgaagag gaccagcatt ttgaactaat
     2101 ccgctatttg aaagacgaat cgattatcgc gtcgatgggg cacacagatg ccgactccgc
     2161 attactgtcg gaggccgcga aagcaggcgc gagccatatg acccatcttt acaacgcgat
     2221 gagcccgttt catcaccgag agcccggagt gatcggaacg gcacttgccc atgatgggtt
     2281 tatggcagag cttattgccg acggcatcca ctcccatcct ttagcggcaa agcttgcttt
     2341 cttggcaaaa ggcagcacca agctcatttt aattaccgat tcaatgaggg caaaaggcct
     2401 gaaagacggc gtatatgagt tcggcggcca aagtgtgacg gtaagaggaa aaacagctct
     2461 tctttcagac ggaacacttg ccggttcgat cctcaaaatg aacgaaggcg cacggcatat
     2521 gcgtgagttt acaaattgtt cttggacgga tatagctaat ataacttctg caaacgcggc
     2581 caaacagctg ggcatctttg accgaaaagg cagtgtgaca gagggaaaag atgcggatct
     2641 tgtcattgtc agcagtgatt gcgaggtgat tctcaccatt tgccgcggaa acattgcatt
     2701 tatatccaag gaggctgacc agatatgaaa gtaatagaat gtcaaacata tgaagagcta
     2761 agccaaaaag cagccaaaat agcggcagac acaatcaagg aaaaacctga cgccgttctc
     2821 ggtttagcga caggcggcac accggaaggc acgtatcgcg agctgatccg cctgcaccaa
     2881 actgagaatc tctcatttca aaacgtcacc acggttaatt tggatgaata cgccggactt
     2941 tcaagcgatg acccgaacag ctatcacttc tatatgaatc atcgtttttt tcagcatatc
     3001 gatagccttc caaaccggca ttttatcccg aatggaaatg cagacgacct ggaagccgaa
     3061 tgcagacggt acgaacaagt agtcgaatcc ctcggcggca ctgacattca gcttctcggc
     3121 atcggccgaa acggacatat cggctttaac gaaccgggaa cgcctttcaa gtcgcggaca
     3181 cacgttgtga ccttaaatga acaaacccgc caggcgaatg ccagatattt tccttcaata
     3241 gacagtgtgc caaaaaaagc gctcacaatg ggaatccaga cgattctcac aagcaagcgc
     3301 attctgctgc ttatttccgg caaaagcaag gcagaagcag tgaaaaagct gttagaagga
     3361 gacataagtg aagatttccc tgcatctgct ttgcacctgc attccgatgt aacggttttg
     3421 attgatcgtg aagcagcggc attaagacct tgaaaggaac atgctgactt atgaagatcg
     3481 ataaacaatc gcctattccg atttattatc agattatgga acaattaaaa gcgcaaataa
     3541 agagcggaga gctgctgccg gatatgcctc ttccctctga gcgtgaatat gccgaacaat
     3601 ttgggatcag ccggatgacg gttcgccagg ctctttctaa tttagtcaat gaaggctttc
     3661 tctatcgcct taaagggcgg ggaacctttg tcagcaagcc aaaaatggaa caagcactcc
     3721 aagggctgac aagctttacc gaggatatga aaagccgcgg gatgacaccg ggcagcaggc
     3781 tcattgacta caagcttatt gattcaacgg aggggctcgc cgctatatta ggttgcgggc
     3841 acccctcccc tatccatcaa gtcactcggg tgcgactggc aaatgatatt ccgatggcga
     3901 tcgaatcctc gcatattccg tttgagcttg cgggtgaatt aaatgaatcg cattttcagt
     3961 cttcgattta cgagcatatt gaaaggtaca acagcatacc gatttccagt gcaaaacagg
     4021 agcttgaacc aagcgctgca acatctcaag aagcaagcat tctcggcatt caaaaggggg
     4081 cgcctgtcct gttaatcaaa cgaacaacat atttacagaa cggaactgct tttgaacatg
     4141 ccaaatctgt atacagaggc gaccgttata catttgtcca ctatatggat cggctttcat
     4201 aaaaaaacct ccaatccttt ttaaggattg gagacatggc gaaaatctaa ctggtctggc
     4261 gccggacgat atgtctcttt tttcgtcttg aacttccaga tcggtgattt cgttttgccg
     4321 ttaaaactgt cttctacaat gatgtaccaa taataaacag aatgcggctc gagatgatcc
     4381 cagcggaatt cagcagtatc cccgctcttt acttgctccc gttttccgag ctcttcattg
     4441 gtatatacat tacactcaaa ataatcggtt tccacctttt tgatcctcgg cttcaaatca
     4501 agcgaaagag aaaactcatc cttgtcaccg tgggtatccg catcatagta gtttttatct
     4561 tgtaaatgcg gagagtacgt cgacacatgc accatatcat tcgcctggtc aaattgcagc
     4621 aaacgcaaat acccttgccc gccttctggc ccgccctgat aatcggccag catttgatgc
     4681 acgaggcgat ccggttttcc atcaccatca tcatcaagct catcagtttt tctcatcgca
     4741 ctatgataat gtccgcttaa caccatcacg acattcggat tcgtcttcac gactttttta
     4801 aatattttct ctccgatcgg gcttctgttt ccgctgacca gcaaatactc atgaaaagct
     4861 aaaacagcca tccggtcagg gtgcttcttc agtacctgat tcatccatgc gatgtcttca
     4921 ttggtaatgc cccatcccat gtatagcatg atgtaatcat tgccgttgct tgaaatcagg
     4981 tcgtaatgcc ctcggttatt tttataggaa ccgccataat gcaatttttt atcaaaacga
     5041 tcactgccaa agtatttgcc aaacgccctg taggagccgt ccttatgccc gacatcgtgg
     5101 ttaccggcca gcacgccgta aggaatcccg cttttatcca gaacggacat tgaccgattc
     5161 gcgtttttcc actgtctgat atcagctgaa tcatctacaa tatcacccgt gtgaaacaca
     5221 tatttgatat tgagttgctt ttgattatct tttatccatg cagtttgttt atcaaaaata
     5281 tgcggatagc tttcggcgta atactgtgta tcggacatcc agacaaatgt gtacatatcc
     5341 ttcgcaggag gaatttcatc ctgtacgatc acattcatct tcgacttccg tacaaaatcg
     5401 gaggcgatca cagacgcctt cagcataaac ggtttgtcat tctttgcaac aaagctgtca
     5461 accggctgcc actcgtttgt ccgataattc caaacataca tcgtcacctt tctccccggc
     5521 aaagaacttc ccttccagac tgcttccgcc aagtcattct catcaactga cggatcaacc
     5581 gccacttcaa agcgatgata agggaaaagt tccttctttt ctgtcgatac tgtttttccg
     5641 tcagcagcag ataccctctc caattcttta ttcgtaaatg gggtctcgct ttccggcaca
     5701 aagcttttcg gcggctcagt cagtgacgca tgcttgaata ttttcacatt gtttcgcgct
     5761 gtatattgaa atcctctata aaaagcgaca tccatggcgt cattcgtcgg atccttcacc
     5821 cgcacagaaa gcttagccct atgcgtgtcg gcttcgctgt ctatgacctc cggctgatct
     5881 ggatgctctc gttctgtttt aaacgtccgc tcaatgactg ttttattgcc cgcgagatcc
     5941 gttgctgtca cttttagcga atgttttccc ggcaaaagtt cagaagatga cgtatggtat
     6001 gggagtgtaa tgctttcacc atctaaagac gccttcactt cctcaatttt gctccattta
     6061 tcatacatat ccgcctgcag gatgaggttt cctttgtacg tttgtccctc ggtgatattc
     6121 ggctcaatgt gaggccctga attatctacc cgcacaacca agcttacatt ttccttgccg
     6181 tcgctcgctt gaatatggtg aaccccttca gaaagctttg atgtatccca ctccagcagc
     6241 tgtgacgtaa acagtccgtc aggcagattg aattgaaatt gccagctttt attcgagcgc
     6301 tgattatctc caataaagag ttccttctca ggagaaaccc tctgatccct gatcaccgta
     6361 ccatccgata acaccagtcg ggcgtttttg actaagaaat catcacggtt ttcagccgta
     6421 tcaaacggcg atacctttga acctgatcgt atcgtaatat gctgcagctg cttccctttg
     6481 cgaagcagcg tctccggcaa tggaacagaa taggtgcggt atttatttgt cgtatcatcg
     6541 aacaccttta atactttgcc ttccatcgtt accgcgtttt taaagtaaag attcgttttt
     6601 ctcgtatcga acgcaaaata cacttctttt tccatagcgg gctctgtcac ttgttttttt
     6661 ccgtcaatcc acagcctaat gctgtcagtg cgcccgtctg tcgtcgcttt tagaaactga
     6721 gttcccgata gcgtatctct gttttcaata ttcatccgca aaccgtgcga cttgcttgtt
     6781 tgtttaatat caatcatttt gaccggggtt cttgcttcat tgatcccgtc ccctgcagtc
     6841 acgtaatact caagctgatc cttcccgatc agttcaggcg aatacacaat ataatgatag
     6901 agattgtcgt tgcggtcttt ttcagcgaaa atgcgcttaa acggtttgtt ttcatctgtc
     6961 cgatagtaga aagccgccgt tttcacaaga ctgcgatccc gtatgtcagc acgcagctca
     7021 atgctttcag caggacggac aggcttgcgg tcagtcaaat cctcaatgac tggtttttct
     7081 ttatcaagct tgatttttcg tttctgctca ggcacctgcg cctgtaatac agttccgggg
     7141 gacggattct tttctccgat tgaaatattg agaagttctg cggtaccgtc catcggatac
     7201 ttgtaaagca cagacgacag ccggcgcagc gcatgtttcc gataatgtgc aaccgaaata
     7261 tcttttcctg tattcgttga tatcacggct gcacgcggtc tggtattggc catgccctct
     7321 gtctcttcta tcaccgcaag atttttccct tccgttaatt gtgtctgata atatcgattg
     7381 aaatcctccg ccgtcaattc tggatgtccg gcaggcttca gccaaaacac aaacgtttca
     7441 ccggatggaa tcgtgatctt tttttccggt ctccaaatca gatcggagtc aggcccttct
     7501 ttcggatagc ggtaacggat gtgatagtct ttaaaatcaa tcgttctgtc agtcgtatta
     7561 taaatctcaa taaattcata accgtctgca cgtccaatgt tctttgtatc aaccgctagt
     7621 tctgtgatca gaagctccgg gatatgggca agatcagcct gatatccttc gagcttcagt
     7681 ttcttcatct ccgactcgac ccgctgcttc ccattggaaa ccacaatgta atactcaagc
     7741 tcgctgttcc aaatcaatcg tttcggaatt tgcgcgaaaa acttgcggac cgctccaggt
     7801 gtcggatcca tcggcaccat tttgtagccc agctcattac tttgtttata aaacagaaag
     7861 gcagaaaatg cttgatactc attgtcacgc acttgagcct caatcatcag attgcttttc
     7921 atttcagctt tcacatcgat ttgaggagga ttttcaagca agggtatgta atgaggcgtt
     7981 tggaatggtt cctgatttat aacaggaaaa gctttcggtt catgatggcc gccagacaaa
     8041 actgaaagaa aagacaagaa taaagaagca ataacagtgt atttcctcat caaaacacct
     8101 cccttttcat gtattttgcg tctgaacagg gaagcttatg agttcatttt tgtgcataaa
     8161 gaacaaaaaa gcgtctgcct cttgaagatt ccactattac ccagtaaact aaggatagtt
     8221 aaccagttaa caattaaatc agagaggcaa attgatggac aacagtattc atgatgaatt
     8281 aattcaagct atacaacaat tcgctttaaa aagggataaa cgtgtcatgc aaaaggtaca
     8341 gataccatcc cgcgacatgt cctcagaaca tctcgaacat ctcagaaaag aatggacatt
     8401 gacccagctt cacattgttt cctgtataca taccagccaa aatgtgaaca acagcttctt
     8461 agcatcccgc ttacatattt caaaagccgc tgtttcaaaa gcagttcaag ctttgttgaa
     8521 acacaatatc atcacagtga caaaaaagcc cggcaacaaa aaagaaattt tttatacgct
     8581 aactgaaagc ggcagagaac tggcggcatt acatgaacag cttcatgaga aagcaaagga
     8641 gcaatacaaa cagctcttca atgaattttc aattgatgat ttaaaaacag tgactgcgtt
     8701 tttcaacttg tgggtaaaac atatgtaaaa aaagcctccc ccgcatggga gagacctttg
     8761 aaatcttatt acgccctgtc aaacgcaacg tgaagtgaga caggtccgcg tgtatacaga
     8821 ccggactcag cataacgaaa accttcctct aatctgatat tccgcatctt atccagcaca
     8881 atattggcta caatctcgat ttcggttttg gcaaaagctg ctcctacaca gttatggatg
     8941 cctgatccga aagcgagatg ccgggcggcg ccgctaaaag cgctcttgat gccgagatct
     9001 tcccgatgaa tataaaacac gtcaggacgt tcaaacgctt cagggtcccg gttagccgct
     9061 ccgatcatac aaaaaacaat cgtatctttt ttgatttcca taccgccgac caccgtatct
     9121 tgggacagct gccgcggaat cagctgaacc ggcggtttat accgcaacgt ctccgcaatg
     9181 gctcttggca ctaacgaacg gtcagccaaa acatcattca tctgctcggg attgttgagc
     9241 aaatgataaa tcatcagtgc cagcgtctta tctgccggtt ccgttgcggc taacagcaca
     9301 ttgagtatca gtgccagtat atccttgtcc gacatcgcca tgccttcata ttcagaagta
     9361 cataggatgg aaattaaatc agatcccgga ttgacgcggc gttcttcgat gaccggcatc
     9421 aagtattgag aaagctgttc gctgcaccat aaagaatgcg cccgcgcttc tggagtctga
     9481 gagatactcg taataaaatc ggcaaccccg ctgtgccact cagcgatttt ttcatgatct
     9541 cttttatcca gcccgagcat gtccatcgtg acacacactg caaacgtctt tccaaaatca
     9601 ttgacgagat cgattcttcc tctttcaaga taaggtgcta acaagttttc tgcattttgt
     9661 ttaatcaatg gagacagatg atccaatgcg tcccctacaa agcttctcac tacaattctt
     9721 cttttagcgg agtgttcttt cccatgcatt tgggccagca cagggccgcg catgaccggt
     9781 tcagcacgct gaacaagtga ttttgtcgtg aaaatatcag gatgctgaag gatatagcgg
     9841 acatcgtgat agcggctgat aaaatagctg tctatcgact cttcataatg aacaggatct
     9901 tcctcccgca gctgtgaaaa ataagcatat ggattttctt gaaattgatc agaaagcacg
     9961 ctaaacaatt taatggattg attcatgtta actcccccta tcatccttca gatgtgatcc
    10021 gtgtttcaga aagcatctgc gccatttctt gcacaatgag atacccttga ttcggccgca
    10081 tacgaataga aaattcatgg ttactgatct tctcacccag cttccacgga cgatgataag
    10141 caaggagcgt ctcttccacc tcaagaatat ccggagctcc gataaaaaac ggcagctcag
    10201 caatgacata ttccacagcc aaattcagca tatcctcact gacttcttcc atcatcaaac
    10261 tgattccgcg tgcacgcccg ataatcgctt catgagacat gtccaaacaa gcatgccgaa
    10321 aatgtggctg ctcaaaaaac gcatgttcaa cttcttgtct catcagctga taggctttgt
    10381 tttccgtgaa atcagaaaat gtatgaatcg ccttcgtgtc cccgccatga gccgcaagag
    10441 ccctttctgc aaatctcctg tttcgcgata cctctttcct tacctttcgt tcagccttgc
    10501 ctctgggagt gccgagcgct tcaagaaggt tagccgcctc atgccccgca agcaaaacgg
    10561 aaacgctttt aaattcagct gtcgcccatc caatcaatct gtaaatataa tcttcagaaa
    10621 acctgctgtt aaatgggctg atccccacca aaacatgctg gcgccgttca aatatttctc
    10681 tgcaattttg tgtcagtggc tcagcagtaa aatctatagg ctttctttcc gtcgccattt
    10741 cggtcatctc attcacccct aaaaaactta tcccgcttta agtcatcacc ctcataaaga
    10801 attggaacaa ctggcacaac tgaacaagac gaatggcagg cagcacttaa agttaccaag
    10861 cgaattatgt taagattcaa acttctatgt tcatttttca aggtgcatat cataattaat
    10921 gtttactagt aaacattagt cattttatcc cttattcctc tacccgtcaa tataatctgt
    10981 acccaaatat ttgaaaataa atgtaaatgt cacatttttc acacactttt tacactcata
    11041 ttcagcatga cacaacacca aataaagctt aaacaccagc aattgacaac gaaaacaaga
    11101 aaagataaaa taatattgtt caccggtaaa caatattgtt tattgtttca tcgtaaacta
    11161 ttattcctaa gaaagaaggt agcctatgtc tgatttgacg aagcagatga tatacgacat
    11221 atatgtgaga ctgctgcacc ttaatgaaca aaaagcgaat acttcacttc agcaattttt
    11281 taaggaggcc gcagaggagg atgtgatcga tatccctaaa aacatgacaa gcattcatgt
    11341 cattgactgt atcggccagc atgaacccat taacaatgcg ggaatcgcca gaaaaatgaa
    11401 cttatcgaaa gcgaatgtaa cgaaaatcag cacaaaactg atcaaggaag aattcattaa
    11461 cagctatcag ctgacagata acaaaaaaga agtgtatttc aaattaactc gtaaaggcag
    11521 acggattttc gacttgcatg agaaattgca taaaaaaaag gagctggctt tttaccaatt
    11581 cctcgattca ttttcacaag acgaacaaaa tgctgtattg aaatttctag agcagctgac
    11641 atctacactt gaagcagaac aaaacgatga gactccggac aaacctgtaa agtaaacaaa
    11701 aaggcggtgt acacttatga ctcaaacaaa atcaaaggcg gtattgatct tatacattgt
    11761 ttgcttcagc gcattttttg catctttaag ccaaaacatt tattcaccta ttatcccgat
    11821 tattaaagaa tcattccatg tttccgcagc aatggtaaac ctgtcagtct cagtttttat
    11881 gattgtgaca gcgattatgc aaattatatt agggaccatc atcgatttta aaggcgagcg
    11941 gtttgtcttg attgccggaa ttatggcaac ggcagctgcc agcatcggct gtgcggtaac
    12001 cactgacttt actttatttc tgatattcag aatgatacag gctgcgggat ctgcagcact
    12061 gcctcttatt gctgccacaa cgatcggaca gctgtttaca ggcagtgacc gcgggagtgc
    12121 aatgggaaca tatcaaatgc tcctgtccgc cgcgccggct atcgcacccg ttctcggggg
    12181 attcataggc ggagcagccg ggtacgaagg gatcttttgg atgcttacgg ccatctctgt
    12241 cgttatgctg gtgacaaaca gcatcatctt tcctaaggac tctcccgctg gatctaagca
    12301 gcaagcccaa ggcaatgtgt tcgctcatta caaatcaata tttacaaatc gaacaggaaa
    12361 cgtcattttg accttaagtt ttgtcctctt tttcatttat tttgcggtga tcgtctacct
    12421 cccgatattg ctgacggagc actatcatat tgatgtgagc atagcaggat tgttatattt
    12481 gccactggcg ctaagcacga ttgccggtac gtttctgttt aaaaaaatac aggcaaaaat
    12541 cgcgctgagc accttgttta tcggcagcaa tgtaatcgca gcctgcagta tcatgttgtt
    12601 cgccgttaca cattccgttt ctctcattct catggctctc acactggcac tgtttggcat
    12661 ctcgatgggg gtcatccctc ccttgtactc cacaatgatc accaatgaat ttgaacacaa
    12721 tagagggagt gcaatcggag tttttaactt tatcagatat acaggcatgg cggcaggtcc
    12781 gatgatatcc gcctatctgc tcacactgat gccgtctgcc atgtcctttg gactcttagg
    12841 ccttatattt gccgcattga gcttttgcct tctgccgcaa atgtatccgc cgcagaagcg
    12901 cgtaaaacaa aaaaaacacc acatgtaaaa aaagctgcct tctgtatggc agcttttttt
    12961 atttctttcg cagcggctct aaaatgcctt tttgaatcag caagtggaac accgacagga
    13021 taacagatgc ccatatcgct gtgccgaagc cgtcaatttg aaaactgtca cccataatgg
    13081 acgcggtcat catcagggtg atggcgttaa tcacaaacaa gaagagacca agcgtcacca
    13141 tcgtgaccgg cagtgtaaag ataatcaaaa gcggtttaat cagcacgttt aagatcgata
    13201 aaatgagact ggcgataatc gctgccccaa tgctgctaac atgaatggag tcaatgtatc
    13261 catcaatgac gattaataac aatgcattta ccaaaatgct gactgcccat tttaccatgt
    13321 catttcatat ccctttctga cgggacgata aaaatccaaa tgatataaat gagcaaaaca
    13381 gggaaaacac ttgtcataat agctaggatg acagttatga ctctgaggag tgatgcatcc
    13441 caattgaaat attccgcgag acctccgatg acaccggcca ttttcttgtt tttttctgaa
    13501 cgataaagcc tattcatttg atcacctctg tgagtacttt agtttgatgg tgcctgttaa
    13561 tgattctgag aagacggtga tgttttgatc atgtgcctga tttgaagtga acaacatttc
    13621 tttttgaatg gtatcatttt tttctttcag catctcaaca tccattaatt catgggacaa
    13681 cgaaccaaga ttgcttttta gctctgcctt cactgcaaga tcgtccggaa tcgaaagctc
    13741 cacatttcca gttgttgttt tggtataaat ggagcggcag tcagagtctg ttacgtgaat
    13801 cgcaatattt ccgttaaagc tttgaacgtc aatggattcg cttctcccac ggagatcgat
    13861 caatccgtta atggtttccg cttctatcgt gccacagctg tggctggcaa gcttaatttg
    13921 cccgttggcc gtttcggctg tggctttttc ggctgttaaa tgcgagaacg acagcacgcc
    13981 gtttgtcgtt ttcgccgaga actcttttac atgtaaatgt tcccctctga ccggaccatt
    14041 aaacagcttc acccgaatct tatcatactc cttctgagga atatataaag tcacattggt
    14101 tttcattgtt ttcttctcag tacggataaa aaacttattt cctttgattt cacattcaat
    14161 atgctgaaga aatgcatgtc tcgccgcatc ctgactgtca gcgcgatata ccttcgcctg
    14221 gcattccgct ctgatatcct cgtcttccca agggacgata ttcacgctgc cgttggcaat
    14281 ttgaagctca acactggaga agtcagtatc tttaaattga aaaatgtgct gaacatcata
    14341 cgcatggcca aagttcaaat caaggtcaac ttccttgacc tttttcacag cggaatcaat
    14401 ccaatcaaac agcttggctc ctaaagacgg cttgctgctt tctttttttt ctgctgtaaa
    14461 cggctcttcc tcgtcatgta catgaactga gagcgctgtg attttttctt ctttttcctt
    14521 gtagtcgctg tcaagttttt caatcagtgt caaagcctct tgtgctgtaa gctttccttc
    14581 ctcaacaagc ttaaggattc gttccttttc ttgcttcatg acgatctcct ccccattgtc
    14641 tacttatgct gcacgcagca ccttaatgcc ctgaatcaca ttccaaatca taatgccaat
    14701 aacaactaag aaataaataa ctgctccccc aatgatcaca aatacaggca gcaggctgtc
    14761 tccatcaatg gcaatggctc cgcccagaaa agcgataaaa aggaccagcc agccggcaaa
    14821 aggaacaatg tgagaaataa gagaacgtat cgcatggcgt tttgtttctt tctcatctac
    14881 aacaaaataa gcgacaatcg gcacaatgat tggcgcaatg aacacactga aatagcaaag
    14941 tgatgcaata atagcttgat tacggttcaa ttcattccac actcctattg tgaattttac
    15001 ccatgacaaa agatcaggga cgttttactt atatatacgt ttaaaacgtc agcaggtttc
    15061 aaattcattc tttagacatg ctccgattta cggaaattgg attttaaaaa gttttagaag
    15121 tagaatcttc cggctgtacc gattacaata tgtaaaaagc ttacggcaat caaggaggct
    15181 ggacaagcaa tggagaaaga ccccagtgac tatacagtaa cacaggaatc ggtgttaaag
    15241 ctgattcgtg aacaaaaaag aatgaatcgt gaaatgatcg ctgagcttga acagatccac
    15301 ggacctcttc cgatctctca cgatattcaa tacataaaag tactgcttga cagcagcaac
    15361 acgcatatcg ttcaagattt aatgagtgta agtaagcagc tgtataagaa gactttgtaa
    15421 ttgcggaaaa agttgcattc attataactg aaatcaagct aaaggttaga tgacaatatc
    15481 ttgccttttt tgttttaaag aaacaagtga ctccctggct gtcacacaat gattgtaaca
    15541 aaaaaagcct gccggcatat ccaactaatg gacctgtcgg caagctgtaa ctatcagaaa
    15601 tagatagccg ttcagaaatt aacgtaataa ttgaagtacg ttttgcggct gttggttcgc
    15661 ttgagcaagc atagcttgag aagcttgaga aagaatgttg ttctttgtga actcgctcat
    15721 ttctttagcc atgtcaacgt cacggatacg agactcagca gctgtcaagt tttcactaga
    15781 tgcgcctaag ttgttgatag tgtgctctag acggttttgt accgcaccga gtttagcacg
    15841 ttgttttgac acattgttga ttgcagtatc aatactttca agttgagtat caaaaggagt
    15901 agtagcaaaa tcttttacat taagtgtgtc tactcctaaa gcatttgctg acatgctatc
    15961 aatgttaact gtaagctgtt ggccagcatt tgcaccaatt tggaaagtga aaccatcagt
    16021 ttcagttcca tctaataact ttttgccgtt gaactcagta cgatttgaaa tgccgtcaat
    16081 ttcttcaata agtgcatcca tttcatcttt aattgcacca agatcttctg cttgctgtgt
    16141 acctgtgttt cctgcttgaa ctgtaagttc acgcatacgt tgaaggatcg catgagtttc
    16201 agtcaatgca ccctcagctg tttggataag agagattccg tcttgagagt ttttagaagc
    16261 catttctaaa cctctgattt gtcctctcat tttttcagag atcgcaagac ctgctgcgtc
    16321 atctcccgct cggttgatac gaaggcctga agaaagtttc tccatgttct tttgtgctgc
    16381 accgttgttt gaagataaac ggttcagtgt gttaagtgct gcgatattgt ggttaattct
    16441 catgtgtaaa atacctccat gtgtatttgt ttttgaaatc aaagacttcc ttttctttga
    16501 tttctggcgt atgagatccc agtaaagctt ctaacttatg tagatccggt tattgattaa
    16561 ggatagattc aaatccctta ataggacttt tttgcttaat atggaaaaca tcatccgcct
    16621 ttcaattcat ttatcggtag cactttgtaa atgtttaggc attttcccaa agaaattttc
    16681 cccattttaa aaagactatt ctaaactatc acacaaaaac cctaaagaaa aagcttgcct
    16741 gctaagcccg aggatggact tgctgacaag ctgaattccc tctgaaaaga ggattttaag
    16801 atgttgccgt ttctttcgct tccaagagcg atgtcatgcg ttttttgtca cgctccataa
    16861 caggcttcaa ataacggcct gtatacgatt cttccacttc agtgatttcc tcaggcgttc
    16921 ctgacgcgac aatggttccg cctccggctc cgccttctgg ccccagatcg acaatgtaat
    16981 ccgccgtctt aatgatatca agattgtgct caatgacgag tactgtatct ccattgtcaa
    17041 ccaaacgctg aagcacgaca aggagtctgg cgatgtcgtc gacgtgcaaa cctgtcgtcg
    17101 gctcgtctaa aatgtagagc gtacgcccag ttgagcgttt gtgcagctct gatgcaagct
    17161 tcacacgctg cgcttctccg cccgacaagg ttgtcgctgg ctgaccgagc gtaatataac
    17221 ctaagccaac atcaaaaaga gtttggagct tacgcttgat tttcgggata ttttcaaaga
    17281 aagaaagagc atcttcaacc gtcatatcaa gcacatcaga gatgcttttt cctttgtacg
    17341 tcacttcaag cgtttcacgg ttatagcgtt tgccgtggca cacctcgcac ggaacataca
    17401 cgtcaggaag gaagtgcatt tcaattttaa taatcccgtc tccgcggcag gcttcacagc
    17461 gcccgccctt cacgttaaag ctgaagcggc cttttttata accgcggacc ttcgcttcat
    17521 ttgtctgcgc gaatacatct cgaatgtcat caaacacacc ggtgtatgtc gcagggttgg
    17581 atctcggcgt tcttccaatt ggcgcctgat caatatcaat gactttgtct aaatgatcca
    17641 aacctttaat ctctttatgg ctgccgggct tcgccttcgc tttatgaagc ttttgcgcca
    17701 gcgccttatg caaaatttca ttgacgagag tactctttcc tgagccggaa acccctgtaa
    17761 ccgctgtgaa cgttccaagc gggaacttgg cattcacttt tttcaggttg ttttctgcag
    17821 cgcctttaat ttcaatgtaa cggccgtccg gctttcttct ttcaggaggc aatgggatga
    17881 actttttccc tgataaatag ctgcccgtta atgaatttgg atcttccatc acttcttccg
    17941 gcgtacccgc agccatcacc tgaccgccgt gaatgccggc accaggtcca atatctatta
    18001 aataatcggc tgccatcatc gtgtcctcat cgtgttcgac aacaatcagc gtgttcccaa
    18061 ggtctctcat atttttcaga gcgctgatca agcggtcgtt atcacgctga tgcaggccga
    18121 tagacggttc atctaaaata taaagcacac cggataagcg cgagccgatt tgcgttgcca
    18181 gcctgatgcg ctgcgcctct cccccggaca atgttcccgc tgccctgctc aatgtcaggt
    18241 aatcaaggcc gactttgtcc agaaagctta aacgctccac aatttcacgc aagatcaaat
    18301 tggcaatctg catatccttc tcagaaaggg taagaccttt gaagaaagca agtgcgtcgg
    18361 ctacagactg ctcggtaatt tttccgatgt ggcggccgtc aatcagtacg gcaagcgcct
    18421 ctttctttaa ccgatagcct ttgcatgtcg gacaagactt ctgagacata tactgctcca
    18481 tttgctcacg gatgaaatca gagcctgtct ccttataccg tctttcaata ttgcgcaata
    18541 cgccttcaaa ttgaatttcg ccttcacgga tttgcccaaa atcattttcg taacggaaat
    18601 aaatcaggtc gtctccgctg ccgtacagca ctttatccag ctgatgctgc ggcagatctt
    18661 ttactggcac gtccatatca atcccataat gggtgcagac cgcctcaaga agctgcggat
    18721 aatactgtga actgatcggt gtccaagggg cgaccgcatt ctcctttaat gacaaatctt
    18781 gattggggat gacgagatcc gcatccactt caagcttcat tccgagaccg tcacatgtcg
    18841 gacacgctcc gaacgggcta ttgaacgaaa acagccgcgg ctcaagctca ccgattgaaa
    18901 aaccacagtg cgggcaggca tgatgctcac taaacatcag ctcttcctca ccgatgacat
    18961 caatcatgac ccgcccttca cctaaacgaa gcgccgtttc caatgaatct gacagacggg
    19021 ccgccacacc ttctttcacc acaatccggt caatgacaac ctcaatcgaa tgctttttat
    19081 tcttttctaa ttcaatatca tcagaaagct cagccatttc gccgtcaatt ctgactctga
    19141 cataaccttg ttttctgatc tggtcaagga ctttgacatg ggcgccttta cggcccgata
    19201 cgatcggggc cagcacctga agcttcgtcc gttccgggta ttccagaatt ctgtcgacca
    19261 tttgctcgat ggtctgcgat gtaatctcaa ttccgtgctc cggacaatga ggcttcccta
    19321 ctctcgcata caaaagacgc agataatcat aaatttcagt taccgtaccg acagtagacc
    19381 tcggattgcg gctcgtggtt ttctggtcga tgctgatggc gggagacagc ccctcaatcg
    19441 catcgacatc cggcttatcc atctgtccta aaaactggcg ggcataggca gacaatgact
    19501 cgacataccg tctctgccct tctgcatata tggtatcaaa ggcaagggag gatttccctg
    19561 atccggacaa accagtaaca acgacaagct gatctcttgg aatcgttaca tcgatatttt
    19621 tcaggttatg cgcccgggct cccttcacct ctatccgatc catagccatt tgttcatcat
    19681 ccttccgctt ttagctctaa aagtaaatcg cgaagctccg cggctctttc aaaatcaagc
    19741 gccttggctg cttccttcat ttcgtgctcc atctgttcaa cgactttctg gcgttctttc
    19801 ttcgtcattt tcgacagctt cggcgcggct tttgttttgt attccgcttt atcctcagct
    19861 gctactgtgg cacgaatgac atcgcgaatc tctttattta tcgtttttgg cgtaatgccg
    19921 tgctcttcgt taaaccgctc ctgctgctcg cggcggcgtt ttgtttcatt aatcgcaatt
    19981 tccatagact tcgtcatttt atctgcgtac ataatgacgc ggccttctga gtttcttgct
    20041 gcccgtccga tggtctggat cagcgaacgc tcagaacgaa ggaagccttc cttatccgca
    20101 tccaaaatcg caacgagaga tacttcagga atgtcgagcc cttccctcag caggttgatg
    20161 ccgataagca catcatgctt gccgagacgc agatcacgga taatttcaat ccgttcaagc
    20221 gtcttaatct ctgaatgcag atagtttact ttaatgccga tttcctttaa ataatcggtc
    20281 aggtcttctg acattttttt cgtcagggtt gtcacgagca cccgttcatt ccgctcaatc
    20341 cttgcttgaa tttcaccgat caaatcatca atctggcctt caatcggacg cacatcaatc
    20401 agcgggtcaa gaagccctgt cggacggatg atctgctcga ccatttcatc cgtgtgctca
    20461 atctcatacg gccctggcgt tgctgataca tacacgatat tgtgcatatg cttttcaaac
    20521 tcttcaaaac ggagcggacg gttatcaagc gctgacggaa gccgaaaacc gtgatccacg
    20581 agtacctgtt tccgcgcctg gtctccgtta aacatgccgc gcacctgagg aattgtcaca
    20641 tgcgactcat ccaccacgat cataaaatcg tcaggaaaat aatcaagaag cgtatacggt
    20701 gttgaacccg gaggccgaag cgtcaaatgt cttgaatagt tttcaat
//
