LOCUS       NC_016047              20891 bp    DNA     circular CON 13-SEP-2024
DEFINITION  Bacillus spizizenii TU-B-10, complete sequence.
ACCESSION   NC_016047
VERSION     NC_016047.1
KEYWORDS    RefSeq.
SOURCE      Bacillus spizizenii TU-B-10
  ORGANISM  Bacillus spizizenii TU-B-10
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M.J., Rasko,D.A.,
            Daugherty,S., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Whole-genome sequences of Bacillus subtilis and close relatives
  JOURNAL   J Bacteriol 194 (9), 2378-2379 (2012)
   PUBMED   22493193
REFERENCE   2  (bases 1 to 4207222)
  AUTHORS   Earl,A.M., Eppinger,M., Fricke,W.F., Rosovitz,M., Rasko,D.A.,
            Daugherty,S.C., Losick,R., Kolter,R. and Ravel,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2011) Institute for Genome Sciences, University of
            Maryland School of Medicine, 801 W. Baltimore St, Baltimore, MD
            21201, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000227465.1-RS_2024_09_13
            Annotation Date                   :: 09/13/2024 01:46:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,304
            CDSs (total)                      :: 4,177
            Genes (coding)                    :: 4,051
            CDSs (with protein)               :: 4,051
            Genes (RNA)                       :: 127
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 126
            CDSs (without protein)            :: 126
            Pseudo Genes (ambiguous residues) :: 0 of 126
            Pseudo Genes (frameshifted)       :: 90 of 126
            Pseudo Genes (incomplete)         :: 52 of 126
            Pseudo Genes (internal stop)      :: 16 of 126
            Pseudo Genes (multiple problems)  :: 28 of 126
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:59:30
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2496444
            Orig. end                         :: 2517335
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002905.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="6"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20891
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10891](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10891)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            <159..821
                     /db_xref="GeneID:11240093"
                     /locus_tag="GYO_RS34345"
                     /old_locus_tag="GYO_2677"
                     /pseudo=""
     CDS             <159..821
                     /codon_start=1
                     /db_xref="GeneID:11240093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010328536.1"
                     /locus_tag="GYO_RS34345"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2677"
                     /product="YtxH domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="DDMVGAGYWNEYDRHNGTTIYTKNPALSQFSREQRLSGRWGDQIA
                     KNLAYFIGTVIVRNPDTHGLNEANFTFDENGNITNVNGDELVYDKNLNAMLPAGAIGGG
                     DAIKVTPKSAKKLAEKVNAMVEDLRMMKKEAQNAYQEHDEKVAELKTEFYGQVGHGFYD
                     QLNAQDVTNTLEDIAQSYDKGPIFYDTQAEQSYIDSLQAAITDLEEIVGFGMTRQHL"
     gene            complement(<798..941)
                     /db_xref="GeneID:92812807"
                     /locus_tag="GYO_RS44280"
                     /pseudo=""
     CDS             complement(<798..941)
                     /codon_start=1
                     /db_xref="GeneID:92812807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014470974.1"
                     /locus_tag="GYO_RS44280"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYTKEASKMASFRSVDELNGAIRTHIYRNKSDLTPAAIEVLKVLS
                     RHA"
     gene            complement(1107..2081)
                     /db_xref="GeneID:11242002"
                     /locus_tag="GYO_RS34350"
                     /old_locus_tag="GYO_2678"
     CDS             complement(1107..2081)
                     /codon_start=1
                     /db_xref="GeneID:11242002"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014114354.1"
                     /locus_tag="GYO_RS34350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2678"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_014114354.1"
                     /transl_table=11
                     /translation="MFNEFEFQIDNFMIYCDSKNLSKKTKASYEQTLRLFSIYLRNEFE
                     IDDPRDVKAAHLRKYIKYLRLRGKYTVVSNEGTKNLNNPYARSDHSKAISDTTIANYIR
                     NIKVFFNFLVSEREIKESPASTVANIKPERKKKKLLSLSQIKRLFSAFDTTTFHGYRNW
                     IMVRTLLDTGMRIGECVNLKPEDLDFKAHSILITNPKNKRQRYAFISDRLSKDLRRWLL
                     YRDRFSDSEYLFPTTRGNKQDVSSFEKVLKKAANSVNIEVTPHQLRNNFAKYYLLNGGD
                     FVTLSRILGHSSVEVTQKAYLDFTEDEIAKKYQKHSPLNTFNL"
     misc_feature    2050..2064
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.48"
                     /tool="antismash"
     misc_feature    complement(2218..2233)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.81"
                     /tool="antismash"
     gene            complement(2230..3033)
                     /db_xref="GeneID:11240094"
                     /gene="spo0A"
                     /locus_tag="GYO_RS34355"
                     /old_locus_tag="GYO_2679"
     CDS             complement(2230..3033)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0042173 - regulation of sporulation
                     resulting in formation of a cellular spore [Evidence IEA]"
                     /GO_process="GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /GO_process="GO:0051606 - detection of stimulus [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240094"
                     /gene="spo0A"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390302.1"
                     /locus_tag="GYO_RS34355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2679"
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="WP_003226427.1"
                     /transl_table=11
                     /translation="MEKIKVCVADDNRELVSLLSEYIEGQEDMEVIGVAYNGQECLSLF
                     KEKDPDVLVLDIIMPHLDGLAVLERLRESDLKKQPNVIMLTAFGQEDVTKKAVDLGASY
                     FILKPFDMENLVGHIRQVSGNASSVTHRAPSSQSSIIRSSQPEPKKKNLDASITSIIHE
                     IGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEV
                     AWSRGNIDSISSLFGYTVSMTKAKPTNSEFIAMVADKLRLEHKAS"
     misc_feature    3292..3308
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.05"
                     /tool="antismash"
     gene            complement(3310..4590)
                     /db_xref="GeneID:11240096"
                     /gene="spoIVB"
                     /locus_tag="GYO_RS34365"
                     /old_locus_tag="GYO_2681"
     CDS             complement(3310..4590)
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240096"
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390303.2"
                     /locus_tag="GYO_RS34365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2681"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_014114356.1"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETGLSVNAHAQESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVQVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEAEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNSPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYEKEKAS"
     gene            complement(4765..6495)
                     /db_xref="GeneID:11240097"
                     /gene="recN"
                     /locus_tag="GYO_RS34370"
                     /old_locus_tag="GYO_2682"
     CDS             complement(4765..6495)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240097"
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390304.2"
                     /locus_tag="GYO_RS34370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2682"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_014114357.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGETKAELEGLFLLESGHPVFDVCTEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALQAYQ
                     EGYHRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERQQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKLSESVSNSYYLLEDA
                     TFQMRNMLDELEYDPERLNYIETRLNEIKQLKRKYGATVEEILEYASKIEEEIDQIENR
                     DSHLQSVKKELDSVGKDVAVEAANVSQIRKAWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPIVNGQPVQLTDQGIDLVRFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVVEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     misc_feature    6517..6534
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 20.69"
                     /tool="antismash"
     gene            complement(6531..6980)
                     /db_xref="GeneID:11242003"
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /locus_tag="GYO_RS34375"
                     /old_locus_tag="GYO_2684"
     CDS             complement(6531..6980)
                     /codon_start=1
                     /db_xref="GeneID:11242003"
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390305.1"
                     /locus_tag="GYO_RS34375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2684"
                     /product="arginine repressor ArgR"
                     /protein_id="WP_014114358.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEIMGTICGDDTILIICRTPEDTDGVKNRLLELL"
     gene            complement(7077..7922)
                     /db_xref="GeneID:11240098"
                     /locus_tag="GYO_RS34380"
                     /old_locus_tag="GYO_2685"
     CDS             complement(7077..7922)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390306.2"
                     /locus_tag="GYO_RS34380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2685"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_014114359.1"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVNDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLKTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHVDVLKRMNSFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQEGQELPEEEIIRVVEEAHKTLKEKKADVPE
                     "
     gene            complement(7919..9820)
                     /db_xref="GeneID:11240099"
                     /gene="dxs"
                     /locus_tag="GYO_RS34385"
                     /old_locus_tag="GYO_2686"
     CDS             complement(7919..9820)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240099"
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390307.1"
                     /locus_tag="GYO_RS34385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2686"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_014114360.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.3e-116,
                     bitscore: 386.5, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLSIQDPSFLKNMSIDELEKLSDEIRQFLITTLSASGGHIGPN
                     LGVVELTVALHKEFNSPKDKFLWDVGHQSYVHKLLTGRGKEFATLRQYKGLCGFPKRSE
                     SEHDVWETGHSSTSLSGAMGMAAARDIKGTDEFIIPIIGDGALTGGMALEALNHIGDEK
                     KDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKKIPAVGGKLAATA
                     ERIKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELIENLQYAKKTKGPVLLHVITKKG
                     KGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQRMAREDGRIVAIT
                     PAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFMRHIPNIVLMMPKDENEGQHMV
                     HTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGNDAVILTFGTTIEMTL
                     EAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAVLEGGFGSSILEFA
                     HDQGEYHTPIDRMGIPDRFIEHGSVTALLEEIGLTKQQVANRIRLLMPPKTHKGIGS"
     gene            complement(10001..10891)
                     /db_xref="GeneID:11242004"
                     /locus_tag="GYO_RS34390"
                     /old_locus_tag="GYO_2688"
     CDS             complement(10001..10891)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11242004"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390308.2"
                     /locus_tag="GYO_RS34390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2688"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_014114362.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-63, bitscore:
                     210.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLTSFLAERKKTIENQLSVYTEKLDMPDSLKESMLYSLETGG
                     KRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHK
                     VFGEATAVLAGDGLLTESFKLITSHLSDEVSAEKRLRLVNELISAAGTEGMVGGQVADM
                     EAENRQVTLEELESIHERKTAKLLGFSVIAGAILADAPEEDIETLRTFSRHIGIGFQIR
                     DDILDLEGSEEKIGKRVGSDTTNEKSTYPSLLSLEGAKHKLDVHIKEAKRLIGGLSLQK
                     DLLYELCDLIAARDH"
     gene            complement(10881..11135)
                     /db_xref="GeneID:11240101"
                     /locus_tag="GYO_RS34395"
                     /old_locus_tag="GYO_2689"
     CDS             complement(10881..11135)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /db_xref="GeneID:11240101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390309.2"
                     /locus_tag="GYO_RS34395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2689"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_014114363.1"
                     /transl_table=11
                     /translation="MTDVKKNENMTFEEAMKGLESIVSKLEEGDVPLEQAINYFQEGMA
                     LSKMCHEKLQKVEKQMDFILKEDGELAPFSVQEEDENDK"
     gene            complement(11132..12478)
                     /db_xref="GeneID:11240102"
                     /gene="xseA"
                     /locus_tag="GYO_RS34400"
                     /old_locus_tag="GYO_2690"
     CDS             complement(11132..12478)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240102"
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390310.2"
                     /locus_tag="GYO_RS34400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2690"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_014114364.1"
                     /transl_table=11
                     /translation="MGETAFVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRGH
                     IYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQPD
                     GVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLKRRY
                     PLVKVLVLPALVQGENASRSIVSRIEEANEKEMCDVLIVGRGGGSIEELWAFNEEIVAR
                     AIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTAEVRMT
                     RAMQQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLDRKNRQL
                     ERETYRLEALHPHEQLKQARTRYEEQTNQLRKNMNIQMKQLHSQFQTVLGKLNALSPLQ
                     VMERGYSLAYKEDELIKSVNQIEEKDQLEVKLKDGVLTCEVLEKRGEEK"
     gene            complement(12614..13465)
                     /db_xref="GeneID:11240103"
                     /gene="folD"
                     /locus_tag="GYO_RS34405"
                     /old_locus_tag="GYO_2691"
     CDS             complement(12614..13465)
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240103"
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390311.1"
                     /locus_tag="GYO_RS34405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2691"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_014114365.1"
                     /transl_table=11
                     /translation="MTATIIDGKETAREKREQLAKEVEELKKQGVTPGLAVILIGDDPA
                     SHSYVRGKKKAAETMGMNFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPDHI
                     SEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNIDLSGKEVVV
                     VGRSNIVGKPVGQLLLNENATVTYCHSRTENMTEHTKKADILVVAVGRANFISADQIKE
                     GAVVIDVGVNRLESGKLCGDVEFEGAKEKASFITPVPGGVGPMTITMLAHNTVKSAKRT
                     LS"
     gene            complement(13477..13872)
                     /db_xref="GeneID:11240104"
                     /gene="nusB"
                     /locus_tag="GYO_RS34410"
                     /old_locus_tag="GYO_2692"
     CDS             complement(13477..13872)
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240104"
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390312.2"
                     /locus_tag="GYO_RS34410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2692"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_014114366.1"
                     /transl_table=11
                     /translation="MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQLV
                     HGVLEHQVQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIEL
                     AKRFGDDKATKFVNGVLSNIKSDIDQS"
     misc_feature    13959..13974
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.84"
                     /tool="antismash"
     misc_feature    14103..14117
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            complement(14137..14544)
                     /db_xref="GeneID:11242005"
                     /gene="yqhY"
                     /locus_tag="GYO_RS34415"
                     /old_locus_tag="GYO_2693"
     CDS             complement(14137..14544)
                     /codon_start=1
                     /db_xref="GeneID:11242005"
                     /gene="yqhY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390313.2"
                     /locus_tag="GYO_RS34415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2693"
                     /product="fatty acid biosynthesis protein YqhY"
                     /protein_id="WP_003236896.1"
                     /transl_table=11
                     /translation="MKDNSLLKMDQEDTHLGKVEIAPEVIEVIAGIAASEVDGVAEMRG
                     NFATGVVERFGKVNHGKGVKVDLADDGITIDVYCVVTFGVSIPKVAASVQENIRQTLLN
                     MTSLSINEINIHIVGIQFDTKAQEVQIDEEM"
     gene            complement(14565..15917)
                     /db_xref="GeneID:11240105"
                     /gene="accC"
                     /locus_tag="GYO_RS34420"
                     /old_locus_tag="GYO_2694"
     CDS             complement(14565..15917)
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240105"
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390314.2"
                     /locus_tag="GYO_RS34420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2694"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_014114367.1"
                     /sec_met_domain="RimK (E-value: 1.1e-06, bitscore: 26.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 3.6e-08, bitscore:
                     31.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 7.1e-10,
                     bitscore: 36.6, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 5.8e-06, bitscore:
                     24.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACKELGIETVAVYSEADKDALHVQMA
                     DEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTFVG
                     PSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKATAGG
                     GGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTI
                     HLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEFIYDYN
                     EQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGWAIECRI
                     NAENPSKNFMPSPGEIKMYLPPGGLGVRIDSAAYPGYSIPPYYDSMIAKVITYGKTRDE
                     AIARMKRALSEFVIEGIETTIPFHLKLLEHETFVGGEFNTKFLETYDVMGS"
     gene            complement(15929..16411)
                     /db_xref="GeneID:11240106"
                     /gene="accB"
                     /locus_tag="GYO_RS34425"
                     /old_locus_tag="GYO_2695"
     CDS             complement(15929..16411)
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240106"
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390315.1"
                     /locus_tag="GYO_RS34425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2695"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_014114368.1"
                     /transl_table=11
                     /translation="MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVMQ
                     QAPAAPVQAQAPQAVQPQAQQAAPAPAQEETKQDENLHKITSPMVGTFYASSSPEAGPY
                     VTAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE"
     gene            complement(16568..17224)
                     /db_xref="GeneID:11240107"
                     /gene="spoIIIAH"
                     /locus_tag="GYO_RS34430"
                     /old_locus_tag="GYO_2696"
     CDS             complement(16568..17224)
                     /codon_start=1
                     /db_xref="GeneID:11240107"
                     /gene="spoIIIAH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390316.2"
                     /locus_tag="GYO_RS34430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2696"
                     /product="stage III sporulation ratchet engulfment protein
                     SpoIIIAH"
                     /protein_id="WP_014114369.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDSG
                     EVATEKAPPKQDTKEKNGTETETEKEDGTKGTKDSSADKETSAEASEKGTVVTETADDD
                     LFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLETLIK
                     TQGYEDALVNAEGDKINITVKSDKHSKSKATAIIDLVAKEIKTMKDVAVTFEPSK"
     misc_feature    17211..17220
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            complement(17225..17914)
                     /db_xref="GeneID:11240108"
                     /gene="spoIIIAG"
                     /locus_tag="GYO_RS34435"
                     /old_locus_tag="GYO_2697"
     CDS             complement(17225..17914)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240108"
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390317.2"
                     /locus_tag="GYO_RS34435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2697"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_014114370.1"
                     /transl_table=11
                     /translation="MNKNGLWNVLKKQFLPGQTKDGEKPKLTKYHYFLFVFVLGVSFML
                     VSQLFSSPEKTENAKTITPVSSQDTKDSKEKTAEVFKASKSDEPKDSIDDYEKEYENQL
                     KEILETIIGVDDVSVVVNVDATSLKVYEKNKSNKNTTTEETDKEGGTRSVTDQTSEEEI
                     VMIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKQTIIEAVTRVLDVPSHRVAVAP
                     KKIKEDS"
     gene            complement(17907..18527)
                     /db_xref="GeneID:11240109"
                     /gene="spoIIIAF"
                     /locus_tag="GYO_RS34440"
                     /old_locus_tag="GYO_2698"
     CDS             complement(17907..18527)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240109"
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390318.1"
                     /locus_tag="GYO_RS34440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2698"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_014114371.1"
                     /transl_table=11
                     /translation="MSFLTEWLTTIVLFILFAIVIDMLLPSSSMQKYAKMVVSLLLIVV
                     MLTPIFKLFNTDPAVIFEYLTKNGQSESADIKNQINSKKIEIQASQRAYILEEMAVQLK
                     KKAEERFSHDEYKVGNIKLTAGEKVDSEEDIQTISVYMAPSSEKTVQTVAPVHIDTDHA
                     YVTKEAAEQKEAKQIQSQLADIWEIGSEKITVYMEGGESVGNE"
     gene            complement(18541..19740)
                     /db_xref="GeneID:11242006"
                     /gene="spoIIIAE"
                     /locus_tag="GYO_RS34445"
                     /old_locus_tag="GYO_2699"
     CDS             complement(18541..19740)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11242006"
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390319.2"
                     /locus_tag="GYO_RS34445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2699"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_014114372.1"
                     /transl_table=11
                     /translation="MKRFQWALLLAVLIIAGRADIVQAAGDAEQTEDHAETAEQLAERT
                     AASLETDKISEFWNDIMTEYGGLLPESQKGSIIEFINGDKSFSPQEWLKALFSYLFHEV
                     LANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAINYA
                     TEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPLIFL
                     SAILSIVSTMTEQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDGITLRT
                     AKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKVLSLAFI
                     YKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAGNLTMMMK
                     "
     gene            complement(19759..20160)
                     /db_xref="GeneID:11240110"
                     /gene="spoIIIAD"
                     /locus_tag="GYO_RS34450"
                     /old_locus_tag="GYO_2700"
     CDS             complement(19759..20160)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240110"
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390320.1"
                     /locus_tag="GYO_RS34450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2700"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_003230228.1"
                     /transl_table=11
                     /translation="MQIDIVQIVGLGLIATFLSLIVKEQKPTFAFLIVVFAGCAIFLYL
                     VDQIYDIIRMIEKIAINANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKIEL
                     AGKILILVMAVPILTVIIETILGLIPSMS"
     gene            complement(20167..20373)
                     /db_xref="GeneID:11240111"
                     /gene="spoIIIAC"
                     /locus_tag="GYO_RS34455"
                     /old_locus_tag="GYO_2701"
     CDS             complement(20167..20373)
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:11240111"
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="GYO_RS34455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GYO_2701"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_003153142.1"
                     /transl_table=11
                     /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIYI
                     LFMVATIVDDLFKKIKAVFLFQG"
ORIGIN
        1 catttctttt agaatcaccg aaataattac tgattgcaga ttcaaattca cgcttgcctt
       61 caccgaacat tctaagccct actcgctttt cttgagccat acttagctca cttgaagcct
      121 ctcctttatt tcgtcattga attttgacgg ccttccagga tgatatggtc ggagccggtt
      181 actggaacga gtatgatcgc cacaacggga ccacaattta cacaaaaaat cctgcactat
      241 cgcaattcag tcgcgaacag agacttagtg ggcgatgggg tgatcaaatc gctaagaacc
      301 tcgcctactt tataggcaca gttattgttc gcaatccaga tacacacggt ctaaatgagg
      361 caaactttac atttgatgag aacggaaata tcacgaacgt aaacggcgat gagcttgtct
      421 acgataaaaa cctaaacgca atgctgccgg ctggcgcgat cggcggcggg gatgccatta
      481 aagtaactcc caaaagtgcg aaaaaacttg ccgaaaaagt taacgcgatg gtcgaggatc
      541 tgagaatgat gaaaaaagaa gcgcaaaatg cttatcaaga gcacgatgag aaagttgctg
      601 aactaaagac ggaattttac ggtcaagttg gccatggctt ttatgatcag ctaaatgcgc
      661 aggatgtaac caatacgtta gaggatatag cccagtctta cgataaagga ccgatatttt
      721 acgacacaca ggctgaacaa tcatacatag attcgctaca ggcagcaatt acagaccttg
      781 aggaaatagt cggtttcggc atgacgagac aacaccttta gaacctcgat cgcggcaggc
      841 gttagatcgg atttattgcg gtatatgtgc gtacggatgg cgccattaag ctcgtccact
      901 gaacggaacg acgccatttt agaggcttct ttcgtataca ttcggtttct ctcctcgata
      961 agagacggca accgtagcgg aaaattagac gcacttaaat aagcgttgac ttgtacgctt
     1021 ttttccgata aaatagacgt aggctaggac gtactatcta tcggatttat ttccgctgga
     1081 tggcgttctt tttttttgtt ttttttttat aagttgaaag tatttaacgg agaatgtttt
     1141 tgatacttct ttgcaatttc atcctctgta aaatctaaat atgctttttg agttacctct
     1201 acactcgaat gccctaatat gcgtgaaagt gtgacaaagt ctcccccgtt taataaataa
     1261 tatttagcaa aattatttcg taattgatgt ggagtcactt caatattcac agagttagct
     1321 gcctttttta atactttttc aaagctactt acatcttgtt tgttccctct agtcgtggga
     1381 aaaagatact cactatcact gaatcgatcc ctatatagaa gccatcttcg taaatctttt
     1441 gagagccggt cggatataaa ggcatagcgc tgccgtttat ttttagggtt agtaattaaa
     1501 atcgaatgcg ctttaaaatc taaatcttcc ggcttcaaat taacgcattc ccctatcctc
     1561 atccctgtat cgagaagagt acgaaccata atccaatttc tatacccatg aaatgttgtt
     1621 gtatcgaagg cgctaaataa gcgctttatt tgagaaagag agagtaattt tttctttttg
     1681 cgttcaggtt taatatttgc aacggtcgag gccggacttt cctttatttc tctttcgctt
     1741 accaaaaaat taaaaaacac tttaatattt cggatataat tagcgattgt ggtatcacta
     1801 attgcctttg aatggtctga tctcgcatat ggattattaa ggtttttagt cccctcgtta
     1861 gaaactacgg tgtatttgcc gcgtaacctt aggtatttta tatacttgcg gaggtgggcc
     1921 gccttaacat cgcggggatc atcgatttca aattcatttc ggaggtaaat tgaaaagagg
     1981 cgtaaggttt gttcgtaact agccttcgtt tttttcgaaa ggttcttcga gtcgcaatat
     2041 atcataaaat tatcgatttg aaattcaaat tcattaaaca taaaaaacgt ctcctttcac
     2101 cacatttaca tacggcaaag aagacgttaa attaatcggt aagttttcga gtcatttatc
     2161 gttgtgttaa cgatatttat cggtaaactc tttattgatc acgtaatgca aacccgcttc
     2221 aaaaaagcct taagaagcct tatgttctaa tctaagctta tccgcaacca ttgcaatgaa
     2281 ttcgctgttg gtaggtttag cttttgtcat gctgacagta taaccgaaca gcgaggaaat
     2341 ggaatcaatg ttacctctgc tccatgccac ttcgatcgca tggcggatcg ctctttctac
     2401 acggctagcg gttgtgttga attttttggc gatgtccgga tagaggactt ttgtaatact
     2461 gccgagcaat tcaatgtcat tgtataccat tgagattgct tcgcgcagat agagatagcc
     2521 tttaatatgt gctgggacgc cgatttcatg gataatgctt gtgatgctcg cgtcgagatt
     2581 tttcttcttt ggttcaggct ggctgctgcg tataatgctg ctttgcgatg atggcgcacg
     2641 atgcgtcacg ctgctggcat ttccgctgac ttggcggata tgtccgacaa gattttccat
     2701 atcaaacggt ttgagaataa agtaggaagc gcctaaatcg acggcctttt tcgtgacatc
     2761 ttcctgtcca aaggctgtca gcataatgac attcggctgt tttttcagat ctgattccct
     2821 cagccgctct aaaaccgcaa gtccatccaa atgcggcata ataatatcca atacgagcac
     2881 atcgggatct ttttctttaa acaacgacag gcattcctgt ccgttataag caacaccgat
     2941 cacttccatg tcttcctgtc cttctatata ttcactcaac aggcttacca gctctcgatt
     3001 atcgtcagca acacaaactt taattttctc cacgtttctt cctccccaaa tgtagttaac
     3061 aggattcacc cttgctacat gtttacattc gacaaaaccg ctatataccc tctaaaaaaa
     3121 atcataatca ccaatattag tggcatatct ttgttattct atgtttttct ccgtttttcg
     3181 actaaaaatg aaatttgaca aacaaggaaa cgtgaatttg tcgaaaaatc ttcttttgta
     3241 cattttaccg tatgtattcc gagaagtgaa gagggatcaa aacaaaaaaa ctgccggaaa
     3301 taccggcagt cagcttgctt tttctttttc gtaaatatcg attcctgctt ctgacagcat
     3361 ccattcaata tgaacgccgt agccgcttgt cgggtcattt acaaacacat gggtgacagc
     3421 gccgatcact tttccatttt gaatgatcgg actcccgctc atcccctgta cgatgccgcc
     3481 tgtttctttc aacagtcttg gatcggttat ttttaaaacc attccttttg tcgccgggaa
     3541 tttttgcggt gttgtgctga cgatttcaat atcaaacttt tctaccttgt catcatcaat
     3601 gaccgttaaa atttcagcag gccctttttt gacttcagta gaaaacgcaa ccggcagtgc
     3661 ttgatctgaa atgttgtttt gaatcggctg atgcagtgtg ccgaaaatgc caaatgggct
     3721 gtttctgtta atatccccga tcgttttacg ttctgaggaa aatcgcgcca gtttttctcc
     3781 cggatttccg cctgtccctt tttcaatgga tgttacagtt gatttaacaa tttctccatt
     3841 ttccactacg attggtttct ttgtgtccat gtcagaaatc acgtggccaa gtgctccgta
     3901 tttttttgtt ttcggttcat aaaaagtcat tgtgccgatg ccagcagcag aatccctgat
     3961 gtataaacca attctgtact tgccttctgc ttcatccttt tccggaatga gctttgtttt
     4021 gattttttgt ttgtcacgtt taatgagcaa atctaaagat tctccggttt taccggcttt
     4081 ctgaataaat ggggccacat cattcatttt ttcaattttc tgtccattca tctcaataat
     4141 gatgtcgccc gcttcaatac cggccgtttc tcccggagat tttttgcctt cacttgtatt
     4201 gatttgatga aatccgacga caagaacacc gacggaatga agctttacac cgattgattg
     4261 tccgccaggt atgaccttta aatcaggaag aacctgcact tttgtttttt tgattggaaa
     4321 tccggcaaga tcgtatacta actctgactc acctgatttt ttgcctgtca ccttgatttc
     4381 atgcgggtct ttctttactg taaacgcttc tgatgattct tgtgcatgag cgtttactga
     4441 taaacctgtt tcaatcgctt gtgtttgggt ttcaaatact ctcatttgcg ttggaatcag
     4501 taaatactct tttagcggtt tgcataaacc tacacttaat aacgaaacaa ggagaattaa
     4561 acctactgct tttctgatgt tatcgggcat tcactacttc actctcctcg ctcctatccc
     4621 acaccttctt tatgtcttgc tgctacatct ttaattttgc cttctgacac cttatttata
     4681 actgtcatat aaagaaaaac attggatata ctgatgaacg aatggatgtg tgcgaaaaaa
     4741 aataagctgc gcttctcgcg cagcttaccc agttgttttg acttgatccg cttgttttag
     4801 aagttctttc gcatggcgtt tcgtcaagtc tgttacttcg actccggcaa tcatgcgccc
     4861 gatttccact accttttcct gcttagacag cggcttgaca cgtgtcgtgg ttctgccgtc
     4921 ttttaactcc ttcgcaatat aaagatgcgt atcggccatg gcagctacct gaggcaagtg
     4981 tgtaatacac agcacttgtg atcctattga gactttatgg atcttctcag cgattgcctg
     5041 cgcgactctg ccgcttacac cggtatctac ctcatcgaat ataatcgacg tcacatcctg
     5101 ctgcgaggaa aaaatgcttt tgatggcaag catcacccgg gacagctccc ctccggaagc
     5161 gactttcgaa agggatttca aaggctcgcc tgtgttggtt gaaattaaaa acctgaccag
     5221 atcaattcct tggtcagtca gctgaacagg ctggccgttt acaatcggcg cctcctcatt
     5281 gcgagacgct gttctgacct taaattccgt atcaaaagtt gatttttcca tatagaggct
     5341 ttttaattct cgatgaatct catcggccag ctttttcgcc catgctttcc ggatttgtga
     5401 aacatttgcc gcttccaccg caacatcttt gccgactgag tcaagctcct tcttcacgct
     5461 ttgaagatgg ctgtccctgt tttcaatttg gtcaatctct tcttcaattt tagaggcgta
     5521 ttccaaaatc tcctcaacag ttgcaccgta ttttcgtttc agctgtttga tttcattaag
     5581 acgcgtctca atataattca ggcgttccgg gtcatattca agctcatcca gcatatttct
     5641 catctgaaat gtagcgtcct ccagcagata gtaagagttc gacacacttt cagacagttt
     5701 tttcagcggt tcgttaatat cggatatatc ttcgagctgc gctgatgcca ttccgaccca
     5761 gtccagtccg ccctgctcac tgcgaagcgc gttatatgca ttttgcagcg attcatagat
     5821 cttctcaaag tttgaaattt gctggcgctc ttcttggagc tgttcatctt cattaagctc
     5881 gagctttgcc gattcgattt cttcgagctg aaattgaata aggtccaggc ggtgggccat
     5941 ttcctgttcg ctttcagaaa gctgttttag ctttttaagc agcttcatat accgatggta
     6001 cccttcctga tatgcttgaa gcgcgctttc tacttcggct ccggcaaact tgtccaaaag
     6061 ctggagatga ttttcgtcct ccattaacag ctggttatcg tgctgcccgt gaatatctaa
     6121 taaaagcctg ccgatctctc ttaacgaagc aatcgtgaca agcttgccat taacacggca
     6181 aacgcttttt ccgctcgtgc tgatatccct tctcatgacg atcatttcgt ctgaaacgtc
     6241 gattccctgc tcagtgcata cgtcaaaaac ggggtggccg ctctccaata gaaacagccc
     6301 ttcaagctcg gcttttgtct ctccatatct gacaaattca gatgatccgc ggcctccgac
     6361 taaaagagaa atggcgtcta tgatgatgga tttgccggct ccggtttctc ctgttaaaac
     6421 cgtgagccct cgttcaaaag aaaccgtcag ttcctcaata atggcaaagt ttttaatcga
     6481 tagttcagct aacaaacagc attacacctc ttatctttgt tagatttctg ttacagcagc
     6541 tcaagcagcc tgttttttac gccgtctgta tcttcaggag tccggcaaat aattaaaatc
     6601 gtgtcatctc cgcaaatggt tcccataatt tcatcccagt ctaaattgtc catcagcgct
     6661 ccgattgcct gggcgtttcc cggcatcgtt ttcagcacaa tcatatggct tgctgagtct
     6721 attttcacaa atgcgtccat caatgcccgc ttcagcttgg acaacggatt gaaacgctgg
     6781 tctgccggaa gactgtattt gtaagagccg ttattcgtag gcactttcac aaggtgaagt
     6841 tctttgatat cccgtgaaac cgtggcttgt gttactttgt atccatcctg cttcagcatg
     6901 tcgaccaatt catcctgcgt ttcgatttca ttgcttgtaa tgatctctct gattttaata
     6961 tgcctctggc ctttgttcat gtaagcacct ctatttccag cttatctgtt cttttatgtt
     7021 atatgattct ctgcaaattg tacatgaatg cagaaaaaag gaataatagc gccctattat
     7081 tccggtacat ctgctttttt ttcttttaac gtcttatgtg cctcttctac aacgcggatg
     7141 atctcttctt ccggcagctc ttgtccttcc tgtccctctc ccggccaatg caaatgaagg
     7201 agaaattcaa tatttccgtc tcctcctgtg attggagaaa atgacaggcc tttgcaaata
     7261 tagccttcag ccgcagagaa actattcatt cgcttgagaa catccacatg cactttagga
     7321 tctctgacaa tccctttttt gccgacggat tcccgtcccg cttcaaactg cggcttaact
     7381 agagccatgc agtcgctgcc cggtacgagt aatgttttga ggacaggcag gatgagccgc
     7441 agtgaaataa aggacacatc aattgtggca aactccggca tgccctttgt aaagtctgcc
     7501 ggtgttgcat aacgaaagtt cgtccgttcc atcacgacga cccgttcatc ctgtctaagc
     7561 ttccacgcaa gctgattata gcctacatcc acagcgtatg actgtttagc tccattttgc
     7621 aaagcgcagt ccgtaaaacc gccggtggag gagccaatat caatcataat tttatcattg
     7681 acagagacgg gaaattcctt caacgctttt tcgagcttta agccgcccct gctcacatac
     7741 ctcagcgggt ttcctttgac tgttagcgga aggtcgcgat caattttttc tccaggcttg
     7801 tccaagcggt tttcgtttga atagacgatc cccgccataa tggctctttt ggctttttca
     7861 cgcgtttccg ccagccctct ttccactaat aatacatcta atcgttcttt ctttgacgtc
     7921 atgatccaat tcctttgtgt gtctttggcg gcatcagtaa tctaatacga tttgccacct
     7981 gctgttttgt cagtccaatt tcctcaagaa gcgccgttac acttccgtgt tcaataaacc
     8041 gatcaggtat acccattctg tcgatcggag tatgatattc accttgatca tgagcgaatt
     8101 ctaaaatcga gcttccgaaa ccgccttcta agaccgcttc ttcaattgtt aaaattggca
     8161 agccttcttt taggatactc ttcatcatct tttcatcaat cggcttaata aaacgcgcat
     8221 tcacaacgcg cacggagagt ccttctttct gtagctcttc ggctgcttca agcgtcattt
     8281 cgattgttgt accgaatgtt aagatgactg catcgttccc tggacgcagc acctcccacg
     8341 taccgatcgg aatcgttttc agctgttcat ccatttttac gccgagtccg tttccgcgcg
     8401 gaaaacgcat cgcaatcggg ccttcgtcat agctgagtgc tgtatgaacc atatgctgtc
     8461 cttcattttc atctttcggc atcattaaga cgatgtttgg aatgtggcgc ataaacgcaa
     8521 tatcaaacac accttgatgt gtctcaccgt cagcacctac gagtcctgca cggtcaattc
     8581 caataaacac attggcgttt tggcggcaaa tgtcatgaac cacttgatca tatgcccttt
     8641 gcaggaaggt tgaataaatc gccaaaaacg gcttcatccc ctgcattgcc attgctgcag
     8701 ccatcgttgc ggcatgctgt tctgcgattc ctacgtcgaa cattcggtca gggaattcct
     8761 ttgcgaagcc ttctagcttt gagccgacag gcatagccgg cgtaatggct acaatgcgtc
     8821 cgtcctcgcg cgccattcgc tgcacagtgc cgctgacaag gccgctccat gaaggagctg
     8881 ctgctttcgg ttttacaaag tcaccggtat tgattttata tggtccggta ccgtgccatg
     8941 ttccaatcgt atcggtctca gccggtttgt accccttccc ttttttcgtg atgacatgca
     9001 ggagaacagg gcctttcgtt tttttggcgt attgaagatt ctcaatcagc tcatgataag
     9061 aatgtccgtc caccgggcct aaatacgtaa aaccaagctc ctcaaaaaac attccggaga
     9121 cgagcatgta tttcaggctg tctttgatcc gttccgccgt ggcggcaagt ttgcctccaa
     9181 ctgccggaat ctttttaaac aagtattcga gctcatcttt gacccactgg tacttcccgg
     9241 cagtgcgcag ccttccgagc atagaatgaa tggcaccgac attcggtgca atactcattt
     9301 cattatcatt taggatgaca atcatgtctt ttttctcgtc gccgatgtgg ttcaaggctt
     9361 caagcgccat tccgccggtc agcgcgccat caccaataat cggaataata aattcatccg
     9421 ttcctttaat atcacgtgca gctgccattc ccatcgcgcc tgacagagaa gttgagctgt
     9481 gcccggtttc ccaaacatca tgctcgcttt cactccgctt tggaaatccg caaagccctt
     9541 tgtattggcg aagcgtcgca aattcttttc cgcgtcctgt cagcagctta tggacatacg
     9601 actggtggcc tacatcccac aaaaatttgt cttttgggct gttaaattcc ttatgcagcg
     9661 caacagtaag ctctacgaca cctaagtttg ggccgatgtg gccgccggaa gcggataaag
     9721 ttgtaattaa aaattgacgg atttcatcac ttaatttctc taattcatca atggacatgt
     9781 tttttaaaaa cgacgggtcc tgtattgata aaagatccaa agcggatcaa ctcactttca
     9841 gcatgaattt ctgcaatgat acatgtcttc tgcatgtcga gctggacaac agccagatct
     9901 cagacataaa aaaagacaaa cgcgcttttc cttttcattt ttcatataaa ctgcttacat
     9961 tttaccatat ctcgtgcagc cgcttcaaat taggatcggt ttagtgatct cttgccgcaa
    10021 ttaaatcaca aagctcatat aaaaggtctt tttgaagaga gagtccgccg atcaaacgct
    10081 tcgcctcttt tatgtgaaca tccaatttat gtttggctcc ttccagtgaa agaagtgacg
    10141 ggtaagtcga tttttcgttt gttgtatccg agccgacacg tttaccgatt ttctcttcac
    10201 tgccttctaa atctaaaata tcgtctctaa tttgaaaacc gattccaata tgcctgctga
    10261 aggtacgcag tgtttcaata tcttcctcag gcgcatccgc caaaatcgcg ccggcgatta
    10321 cgctaaaacc aaggagcttg gcggttttcc gttcatgaat ggattcaagt tcttcaagcg
    10381 tgacttggcg gttttccgct tccatatcag ctacttgtcc cccgaccatt ccttcagtgc
    10441 ctgccgctga aatcagctca ttcacaagcc gaaggcgctt ttctgctgac acctcgtctg
    10501 acaagtggga ggtgatcagc ttaaagcttt ccgtcaagag cccgtcaccc gctaatactg
    10561 ctgtcgcttc accgaacact ttatgatttg tcggcttccc gcggcgcaaa tcatcatcat
    10621 ccatacaagg aaggtcatca tgaatcaatg aatacgtgtg aatcatttcg acagcacagc
    10681 cgaccggaat gccgtccttt tcacttttcc cgtatgcgtt taaaacggct agtacaatga
    10741 gaggacgcag ccgctttccg ccagtctcaa gggaatataa catagattct tttaatgagt
    10801 ccggcatatc gagcttttct gtatagacag aaagctgatt ttcaatcgtt tttttccgct
    10861 ccgccagaaa actcgttaat ttatttgtca ttttcgtctt cctcctgaac actgaaaggt
    10921 gccagttcgc cgtcttcttt taaaatgaag tccatttgtt tttcgacttt ttgcagcttt
    10981 tcatgacaca tttttgaaag agccatgcct tcttggaaat agttaatcgc ttgctctaaa
    11041 ggcacatcac cctcttcaag ctttgacaca atgctctcaa gccctttcat cgcttcttca
    11101 aatgtcatgt tttcattttt tttcacgtct gtcatttttc ttcccctctc ttttctaata
    11161 cttcacaggt cagcacgcca tccttcagct tgacctcaag ctggtccttc tcttctattt
    11221 gattgacact tttaatgagt tcgtcttctt tataagccaa gctgtatcct ctttccatca
    11281 cttgaagagg acttaacgca ttcagcttgc caagaacagt ttgaaattgg gaatgcagct
    11341 gcttcatttg gatattcata ttttttctca gctgatttgt ttgttcctca tatcgtgttc
    11401 tcgcttgctt cagctgttca tgtggatgca gcgcctctaa tctgtacgtt tcacgctcca
    11461 gctgtctgtt ttttcgatct aaaagagcgg taagctgtgc ttgaaactgc tgataggcaa
    11521 ggtcaaactg ctgctctttt tgcgcataca aacgctttgg aaaacgaaag gcatacgagg
    11581 attgcagcgt ttgaatccgt tcttttttct gaccgagatg ctgctgcatc gctcttgtca
    11641 ttctgacttc cgctgttttt gtccgttcga ttaaatcagt ggtatgcggt acggcaatct
    11701 cagctgctcc tgtcggtgtc gcagctctaa tatcagcgac aaaatcactg atcgtaaagt
    11761 cggtctcatg cccgacagcc gatataatcg gaatgttaga agcaaagatc gcacgtgcta
    11821 caatttcttc attaaatgcc cacagttctt ctatcgaacc gccgcctctc ccgacaatta
    11881 atacgtcgca catctctttt tcatttgcct cttcaatgcg gctaacgatg gatctgcttg
    11941 cattttcgcc ttgtacgagc gctggaagaa caaggacttt tacaagggga tatcttcttt
    12001 tgagagttgt aatgacgtct ctaacagcgg cacccgtcgg agatgtcaca accccgattg
    12061 tggctggaaa tgcggggatt tgttttttgt agcggtcgtc aaataaacct tctccggcaa
    12121 gcttcttttt taactcttcg tacgctaaat aaagtgctcc gaccccgtca ggctgcattt
    12181 ctttggcata taattggtag tttccgctcg gttcatatac ggaaattccg cctctgacca
    12241 gcaccttcat gccgttttca ggtttaaaag gcagacgctc gctctgtctc gcgaacatca
    12301 ccgactgcat tctggcgttt tcgtctttca atgtgaaata aatgtggcct cttgtgtgta
    12361 tttttacatt cgataattcg cctttaatcc aaatattttc aaggtgagga tctacatcga
    12421 attttcgttt tatatacttt gtcagcgctg agacggtaac aaacgctgtt tcacccatgt
    12481 ctcaaactcc tctcataagc attcctgcac cataactaaa gaaaacccgc cctggcttta
    12541 ggagcctgaa gaagcgggta tcgtgctcat attcacggcg ggcaaaaccc cgcctgtgaa
    12601 tatctccaat tatctatgat aacgtacgtt tcgcagattt aacagtatta tgcgcaagca
    12661 tcgtgatggt catcggacct actccgcccg gaaccggcgt gatgaaggat gctttttcct
    12721 ttgccccttc aaattcaaca tctccgcaaa gctttccgct ttccagacgg ttaacgccta
    12781 cgtcaatgac aacagcgcct tctttgatct ggtctgcact gatgaagttg gctctgccga
    12841 ctgcgaccac caggatgtcc gcttttttcg tatgttcggt catattttct gttcttgaat
    12901 gacagtaagt aactgtcgcg ttttcattta ataaaagctg gccgacaggt ttgccgacaa
    12961 tattgcttcg gccgactaca acaacctctt taccggaaag gtcgatattg gttttcttca
    13021 aaagctcaac aattccgtga ggcgtgcaag gaagaaacgt atcttcgcca agcagcattt
    13081 tccctacgtt taacggatga aaaccgtcta catctttatc aggagagata cgttcgatca
    13141 ccgctttttc agaaatatgg tctggaagcg gaagctgaac gagaatgccg tgaaactcag
    13201 ggtcttgatt gtattgatcg ataatggaaa gcagttcagc ttctgtgagg ctgctgtcaa
    13261 attgatcaag cttgaaattc attcccattg tttcagccgc ttttttcttt cctcgcacgt
    13321 aagagtgaga agcaggatca tctccaatca aaataaccgc cagtccgggg gtgacccctt
    13381 gctttttaag ctcttctacc tcttttgcca attgttcgcg tttttctcta gccgtttctt
    13441 ttccgtcgat gattgttgca gtcattttct ttcctcctat gattggtcaa tatcagattt
    13501 aatgttagaa agaaccccgt ttacaaattt tgtcgctttg tcatcaccaa accgttttgc
    13561 cagctcaatc gcttcgttca tggagacatt caccggaatg tcttcggcat atgccatttc
    13621 gtaagctgcc agacgcaaaa tcgcgcggtc aacattggca atccgatcga gcttccaatt
    13681 caccagatgc ttggaaatca tttcatccag ctggacttga tgttccaata ccccgtgtac
    13741 aagctgttca aagaaaggat ctgttttttc ttcatccagt gcgtgttcta tggcttcatt
    13801 cactgcaata tcgctgacat caatttgaaa tagtgcctgc aaagcttttt ctcttgctgt
    13861 tcttcttttc attttctttc tcctttgatc ctctttatcc gcttgtcgtt aagccacaaa
    13921 gagatcataa catatttttt tcgtatccgc atattgaaat caaggttttt tcaccctatt
    13981 accgaatatt ttcatgcacc ttaatatgat cattcggatt tcacgatcat gaagaaactc
    14041 ggctgccttg agccggcttt cttcatgctt tgaaataaag ggtaacgtgt aaaaaaacca
    14101 aagggccgcc ctccccttgg tttcgtgtta agccatttac atttcttcgt cgatttggac
    14161 ttcctgggct tttgtgtcaa attgaatgcc gacgatgtga atattgattt cattaatcga
    14221 aagagacgtc atatttaata aggtttgacg aatgttttcc tgaacggacg ctgcaacttt
    14281 cggtatcgaa acaccaaatg taacgacaca gtatacatcg atcgtaattc catcatccgc
    14341 cagatcgact ttgacacctt tgccatgatt cactttaccg aagcgttcga cgacgcctgt
    14401 cgcaaagttt ccgcgcattt cggcaacacc gtcaacttct gaagctgcaa tgccggcaat
    14461 gacctcaatg acttccgggg caatctcaac cttacccaaa tgcgtatctt cttgatccat
    14521 tttaagcaag ctgttgtctt tcattcaatt cacctccgta aaaattatga gcccattaca
    14581 tcatatgttt ctaaaaattt cgtattaaac tctccgccaa caaatgtttc gtgttcaagc
    14641 agttttaagt ggaacgggat tgttgtctca atgccttcga tgacaaattc gctcaatgcg
    14701 cgcttcatgc gggcaatcgc ttcatctctc gtttttccgt atgtgatcac ttttgcaatc
    14761 atgctgtcat agtacggagg gatggagtag cccgggtacg cagctgaatc gatacggaca
    14821 ccaagaccgc caggaggcag gtacatttta atttcaccag gtgacggcat gaaattttta
    14881 cttggatttt ctgcgttgat tcggcattcg atggcccagc cttcaaattc aacatcttct
    14941 tgcttgaggc tcagttccat tcctgatgcc actttgattt gttccttaat caggtcagtt
    15001 cccgtcacca tttctgtgac tgggtgctct acctgaattc tcgtgttcat ttccatgaag
    15061 taatagcgct gttcattgta gtcatatata aattcaactg ttccagcacc tgtatagcca
    15121 accgcttttg cagcctttac cgctgcatcg cccatttgct ccctaatttc tgaatcaagc
    15181 gcaggagatg gtgattcttc caaaagcttt tgcaggcgtc tttggatcga gcagtcgcgt
    15241 tcccctaaat ggatggtatt tccgtagtta tcggcaagca cttggatctc aacatgacga
    15301 aaatcctcta tgtatttttc gatgtaaaca cctggatttc caaatgcagt tgcagcttcc
    15361 tgctgggtaa tcttaatgcc gttaatcagt tcctcttcgg tgcgggcaac cctgattcct
    15421 tttccgcctc cgcctgctgt ggcttttata attacaggat acccaatttc gttagcaagt
    15481 gaaaccgctt cttccacatt ttctataatt ccttgtgaac ccggtacgat cggcacgccg
    15541 gcctgtttca tcgtttcccg cgcaacgtct tttgttccca tttttgaaat ggcgtcagcg
    15601 ctcgggccga caaatgtgac gttaacttct tcacataatt ccgcgaaatc tgcattttca
    15661 gctaaaaacc catatcccgg atgaatagca tccgtgcctg tcagcttcgc aacactcaca
    15721 atatttgtaa cgtttaaata gctgtctttt gatgctttcg gtccgataca aaaagcttca
    15781 tcggccattt gaacatgaag ggcatcttta tcagcttctg aataaacagc gacagtctca
    15841 attccgagct ctttgcaggc tctgatgatt ctgacagcaa tttctcctcg gttggcgatc
    15901 aatagctttt taatcatgtt aagtctcctt actctgcttt tacaagaaat agaggttgtc
    15961 cgtattcgac cagctggccg ttttctacta atacttcaac gatttcgcct tttacttccg
    16021 cttcgatttc gttgaaaagc ttcatcgctt ctacaatgca gacaactgtg ttttcattta
    16081 cttttgaacc agccgttaca tacgggccag cttccggaga tgaagatgca taaaatgttc
    16141 ctaccattgg tgaagtgatt ttatgcagat tctcatcttg cttagtttct tcttgggcag
    16201 gtgccggcgc tgcttgctgc gcttgcggct gaactgcctg cggagcctgt gcctgtacag
    16261 gtgctgccgg cgcctgctgc atgacttgaa cagtgcctgc ttcatgtttt ttcagtttta
    16321 aggatacacc ttcattttca tatacgaatt cgtcaattgt agactcgtca attgctttaa
    16381 tcagctcgtg gatttcttta atatttaaca ttcaatcgca ctcctatgta tgaaatttct
    16441 tttttatagg ttactactaa aagtacatac tatgttcatc ttacaggagc ggacttttga
    16501 attcaactct aatatgattg gcacgccaaa aagcccgctg tttaagcggg cgtgtttttc
    16561 ctctttttta cttggatggt tcaaatgtga cagcgacgtc tttcattgtt ttgatttctt
    16621 ttgccacaag gtctataatg gctgtcgcct tcgatttgga gtgtttgtct gatttgactg
    16681 taatgttgat tttatctcct tcagcattga cgagcgcgtc ttcgtagcct tgtgttttaa
    16741 taagcgtttc cagctgtttt tctgttcctt ccacttcact gagagccgtc attttatcat
    16801 atgcttcgct cttttccttt gctgttgcat catcgcttga cacaatggca ttcagttctt
    16861 ctctttcttt gcttctggca tcttctaaat caagacggta cgtcgtgaac agatcatcat
    16921 cggctgtttc tgttacaaca gttccttttt cactagcttc agcggatgtc tccttgtctg
    16981 ctgatgaatc ttttgtgccc tttgttccat cctctttttc tgtttcagtt tctgtaccgt
    17041 ttttttcctt tgtgtcttgc ttgggaggcg ctttttcagt tgcgacctct ccgctgtcag
    17101 acgcgctttt ttcactttgc atttgcacgg catttttgct ttccggcgac atgatatagt
    17161 agacgcttaa caccacgaca agactgagca ttgttaatag ccaaacggtt tgttttttga
    17221 gcatttatga atcctccttt atttttttag gggcaaccgc aacccggtgg cttggaacat
    17281 ccaggacccg tgtcaccgct tcaataatgg tttgttttat ttgaacgttg tccactcctt
    17341 gagcaacaac gagtacaccg cgtatatcag gctttttcgt ttggacgacg actggtgttt
    17401 ccttatcgcc gtttttgatc atgacgattt cttcttctga tgtctggtct gtaacgcttc
    17461 ttgttccgcc ttctttgtct gtttcttcag tggttgtatt tttgtttgat ttgttttttt
    17521 cgtatacttt cagcgacgtt gcatcaacat tcacgactac agagacatcg tccacaccta
    17581 tgatcgtttc aagaatttct ttcagctgat tttcgtattc tttttcataa tcatcgatcg
    17641 agtccttagg ttcatcagat tttgaggctt taaacacttc ggctgttttc tctttgctgt
    17701 ctttggtatc ttgtgatgat actggcgtta tcgttttggc gttttctgtt ttctcaggtg
    17761 aagaaaacag ctggctgaca agcataaagg aaactccgag aacaaaaacg aacagaaagt
    17821 aatgatattt ggtcagcttc ggcttttcac cgtccttcgt ttgccccgga agaaactgct
    17881 ttttcaatac attccataat ccgtttttat tcattgccga cactctcccc gccttccata
    17941 taaaccgtaa ttttctcact tccgatttcc caaatgtccg cgagctgtga ctggatctgt
    18001 ttggcttctt tttgttcggc tgcttctttc gttacgtatg catgatctgt atcaatgtgg
    18061 accggcgcga ccgtttggac cgttttttca gaagacgggg ccatatacac gctgattgtt
    18121 tgaatatcct cttctgaatc taccttttct cctgccgtga gtttgatgtt gcctactttg
    18181 tattcatcat gactgaatct ctcctccgct ttctttttta gttggacagc catttcttct
    18241 aaaatatatg cacgctggga agcttgtatt tctatttttt ttgaattgat ttgatttttt
    18301 atgtcggcag actctgactg cccgtttttt gtaagatatt caaagatgac tgcagggtct
    18361 gtgttgaaaa gcttaaaaat cggcgtgagc atgacgacaa ttaagagcag gctgactacc
    18421 atttttgcgt acttttgcat gctagagctt ggcagcagca tatcaatcac aattgcaaat
    18481 aggataaaca acacgatggt ggtaagccat tcagttaaaa aactcatccg ccagcctcct
    18541 ttatttcatc atcatcgtga ggtttccggc tgtgattatg acggtaaggc ttaaaaaaaa
    18601 catgagagac acaatggcga gagctgcaaa aatataaatg acgcttttgc tgatgacgtc
    18661 gaggcaggtt atgacgggcc cgcctccaag cggctgaaga atcgcggctg ccagcttata
    18721 aataaaagcg agggaaagca ctttgattgc cggaaaagcc gcaatacaga tcaaaatagc
    18781 gactccgaga atccctactg tatttttcag cagtaaggaa gcgctgatca ctgtatctgt
    18841 cgcgtctgta aacattcggc caagcacagg aataaagttt ccggttataa atttagccgt
    18901 cctgagcgta atgccgtctg tcactgcagc tgaggctccc tgaacagaga tgacaccgag
    18961 aaaaatggtg agaaagacgg cgagcgcccc gatggcgata tttctgagca ggttggccag
    19021 ctgcgttact ttatattgtt cggtcattgt gctgacaatg ctcagaatcg ctgataagaa
    19081 aatgagcggc atgacaatat tctgaatcaa aagaccgctc gtgttcatca gaaagaggat
    19141 aacaggatga aagaaggctg cagatacagc tccgcctgag gaagccaaaa gcgctaagag
    19201 gagcggaatg agcgccagga taaagctggt catcgtctga atggcctctg tcgcataatt
    19261 gattgccaca tgaaaactgt ttagcgcaag gataatcagc accatgtaca caattgagta
    19321 agcgacctta ctgacggtgc tttgttgaaa tgcattttgc agaagctgca ggataacgca
    19381 aaatatcgtg agcaaaatca atgtgcccaa cagctttccg ttggcaagca cttcatgaaa
    19441 caaataagaa aagagagctt tcagccattc ttgcggtgaa aatgatttat cgccattgat
    19501 aaactcaatt atgctgcctt tttgactttc cggcagcagt ccgccgtact ctgtcataat
    19561 gtcattccaa aattcactaa tcttgtctgt ttcaagcgag gccgctgtcc tttccgctaa
    19621 ttgctcagcc gtttcagcat ggtcttccgt ttgttcggcg tcaccggctg cttgtacaat
    19681 gtctgcacgg cctgctatga tcagcacggc cagaagcaaa gcccattgaa aacgcttcaa
    19741 tctaccgcct cctttcggtt atgacataga aggtataagt ccgagaatcg tttcgataat
    19801 gacggttaaa ataggcacag ccataacgag aattaaaatt ttccccgcca attctatttt
    19861 cgaggcgatg gccccttgtc cggcatcttt tgtgagctgc gccccgaatt cagcaatata
    19921 ggcaattccg ataatcttta aaatggtttc aacatagacc atgttgacgt ttgcattaat
    19981 cgcgattttc tctatcattc gaataatgtc gtagatttgg tctaccaaat aaagaaaaat
    20041 ggcacatccg gcaaacacga cgattaaaaa cgcaaaagtc ggcttttgtt cttttacaat
    20101 caaagaaagg aaggtggcga tcagccctaa acctacaatt tgaacaatgt caatctgcaa
    20161 gcccccctat ccttggaata aaaacacagc ttttatcttt ttaaaaaggt catctacaat
    20221 cgttgcgacc ataaataaaa tatagataaa acctaacagc gtcacccact gggcgtattc
    20281 ttttttgccc atctgatcca aaatcgtgtg taaaaatgca accacgattc ccactccggc
    20341 gatttgaaat atgacattca cgtctactcc cattttattt ttgctcccct cacgtttaca
    20401 tcaatagaag aatgagtagc aagcccgcta aaaagcccaa actttttatc attttttcat
    20461 ttttcgcttg tgcctgctca gcatccgctt ccgaggcttc caaatgtgtc agcgccagct
    20521 tgatgtgctt ttgctgcgag attcgatcat gaatcccgag cgtctcacca aattgcttca
    20581 gcacttcata ttcgcttttt ttcaaagaca tggtgtccca caccttcttt aagctttgct
    20641 cccacgccgt tttcgcagaa tcacttcctt tgtccagctg atcactgaac gtgataaaaa
    20701 gagctgaaac aggctgtgcc agctgcttgg caatctgctg tgaagcaata tgaagcggtg
    20761 tatggccgta catgatttca gcctcgaggg attggagcgc cgcacgcagc tggcggattt
    20821 gccgcggccg ttctgtgtaa atcttcgcca tctcaaaacc tgtccatgtt gtcgccacca
    20881 caatgaatac a
//
