LOCUS       NZ_GL985606            30001 bp    DNA     linear   CON 21-JUL-2024
DEFINITION  Actinomyces sp. oral taxon 448 str. F0400 SCAFFOLD1, whole genome
            shotgun sequence.
ACCESSION   NZ_GL985606
VERSION     NZ_GL985606.1
KEYWORDS    WGS; STANDARD_DRAFT; RefSeq.
SOURCE      Actinomyces sp. oral taxon 448 str. F0400
  ORGANISM  Actinomyces sp. oral taxon 448 str. F0400
            Bacteria; Actinomycetota; Actinomycetes; Actinomycetales;
            Actinomycetaceae; Actinomyces.
REFERENCE   1  (bases 1 to 2812018)
  AUTHORS   Muzny,D., Qin,X., Deng,J., Jiang,H., Liu,Y., Qu,J., Song,X.-Z.,
            Zhang,L., Thornton,R., Coyle,M., Francisco,L., Jackson,L.,
            Javaid,M., Korchina,V., Kovar,C., Mata,R., Mathew,T., Ngo,R.,
            Nguyen,L., Nguyen,N., Okwuonu,G., Ongeri,F., Pham,C., Simmons,D.,
            Wilczek-Boney,K., Hale,W., Jakkamsetti,A., Pham,P., Ruth,R., San
            Lucas,F., Warren,J., Zhang,J., Zhao,Z., Zhou,C., Zhu,D., Lee,S.,
            Bess,C., Blankenburg,K., Forbes,L., Fu,Q., Gubbala,S., Hirani,K.,
            Jayaseelan,J.C., Lara,F., Munidasa,M., Palculict,T., Patil,S.,
            Pu,L.-L., Saada,N., Tang,L., Weissenberger,G., Zhu,Y., Hemphill,L.,
            Shang,Y., Youmans,B., Ayvaz,T., Ross,M., Santibanez,J., Aqrawi,P.,
            Gross,S., Joshi,V., Fowler,G., Nazareth,L., Reid,J., Worley,K.,
            Petrosino,J., Highlander,S. and Gibbs,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2011) Human Genome Sequencing Center, Baylor
            College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Standard Draft
            Current Finishing Status          :: Standard Draft
            Assembly Method :: Newbler Assembler v. 2.3-04192010
            Genome Coverage                   :: 32.58x
            Sequencing Technology             :: 454
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000220835.1-RS_2024_07_21
            Annotation Date                   :: 07/21/2024 00:51:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,460
            CDSs (total)                      :: 2,404
            Genes (coding)                    :: 2,339
            CDSs (with protein)               :: 2,339
            Genes (RNA)                       :: 56
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 20 of 65
            Pseudo Genes (incomplete)         :: 50 of 65
            Pseudo Genes (internal stop)      :: 5 of 65
            Pseudo Genes (multiple problems)  :: 9 of 65
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:02:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 456944
            Orig. end                         :: 486945
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GL985606.1.
            Actinomyces sp. oral taxon 448 strain F0400
            Strain source, body site: Oral
            Inquiries should be directed to microbe@hgsc.bcm.tmc.edu
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC. This
            sequence is generated as a part of the Human Microbiome Project
            (HMP), funded by the National Institutes of Health (NIH), National
            Human Genome Research Institute (NHGRI) Large-Scale Sequencing
            Research Network and the National Institute of Allergy and
            Infectious Diseases (NIAID) Microbial Genome Sequencing Centers
            Program. The mission of the HMP is to generate resources to enable
            the characterization of the human microbiota, the microbial
            communities living within human bodies, and analyze the role of
            these organisms in human health and disease. See
            http://www.hmpdacc.org/ for more information.
            The sequenced strain was obtained from Dr. Jacques Izard (contact
            information: Forsyth Institute, Department of Molecular Genetics,
            140 The Fenway, Boston, MA, 02135). The genomic DNA was prepared
            from a single bacterial isolate. The sequence generated included at
            least 10 fold coverage of Roche/454 Lifesciences FLX fragment data
            and at least 8 fold clone coverage of Roche/454 Lifesciences
            paired-end data. The Roche/454 Lifesciences sequence was assembled
            using the Roche/454 Lifescience Newbler assembler. This draft
            assembly meets the HMP draft quality standards (more than 90% of
            the genome is included in contigs, more than 90% of a core set of
            bacterial genes are found with > 30% identity and > 30% length;
            more than 90% of the bases in the assembly have more than 5 fold
            sequence coverage, the contig N50 length is greater than 5kb, the
            scaffold N50 length is greater than 20kb, and there is less than 1
            gap per 5kb).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30001
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="3"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..30001
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..30001
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:20001](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20001
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    77..90
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.82"
                     /tool="antismash"
     misc_feature    complement(94..114)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(202..2973)
                     /locus_tag="HMPREF9062_RS02030"
                     /old_locus_tag="HMPREF9062_0441"
     CDS             complement(202..2973)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008732377.1"
                     /locus_tag="HMPREF9062_RS02030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0441"
                     /product="lysylphosphatidylglycerol synthase
                     domain-containing protein"
                     /protein_id="WP_009748344.1"
                     /transl_table=11
                     /translation="MTSDLPPGSQDADTTVESAPATSPVGIPRIGVTPAVPTQQPSPAP
                     SRSRSTTLLVDAAPHRLRRTEDLLDLVLAAIGSASMLILAAYAHETTTGVTLDVQNALA
                     AVLRQILVFPLQTVEGLATFLVPVSVVLASLLRRSWRTAGQAILGGIGGFLLAWAVLAA
                     VTSWAPSAIISGLTVTASGTAKVGISTVFATLAGLLTGAGERRASHAVRRGWTALWVII
                     GLAVLRSALTLPGAVMSVLLGRVLGLAIRYGFGVEDRRAHGTALVRALRRAGIDAVRVV
                     RMDRAPAAKAWTVVTDTPVGYTEQVRENPLTIPAAMPDLDDAGPRLDLTEYPNEPAEVA
                     AALHPEETATITTATDVDLEAIVTEASSAALTVGRPSVHRLYAVWDATGIRRDVTVLDT
                     DSQVAGFVSTLWDRIRIKGLSPERDLSVRSAAEHAALMTLEAHRARVRTPALFGMAEAD
                     ESVLLVADHVIGARALGDLDEVSDDVLAQLWEQLGRAHAAGLAHRAIDSSSVVVDVAGC
                     VWLLDWDSGETISSELSRRVDLAQTLALTASVVGVDRAIAAASRSLSTPQIASIAPMLQ
                     RVVLPATTRDALGEQRGRLLQELRDALVALTPTAHAEPAKLTRFSPRTVVMAVVGLVAL
                     WTLLARMNFSQISAAVAAANAWWILGAVVFSLATYLGAGIALVAFSPVRLSVWKSTEVH
                     LAGAVVSLVAPAGVGGAAINLRFLTRRGVPTPIGVATVALVQVVQFLVTIVLLIILAAM
                     TGQSTGLTLPSDWLVLGAIVLVAVVGSALFVPRVRTWVRAKIEPTYRQVWPRLVWIMSN
                     PLRLALGVGGTVLLSLSYVLAFGGSLWAFGYTLPFSILAITYLASNTVGSVVPSPGGIG
                     PVEIALTAGLVTAGIPSGVALSAAIVYRLVTFWIPIPAGWLSLRHLQRSRDL"
     misc_feature    2964..2978
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.75"
                     /tool="antismash"
     gene            3188..>3949
                     /locus_tag="HMPREF9062_RS12035"
                     /old_locus_tag="HMPREF9062_0442"
     CDS             3188..>3949
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020461.4"
                     /locus_tag="HMPREF9062_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0442"
                     /product="GAD-like domain-containing protein"
                     /protein_id="WP_009748345.1"
                     /transl_table=11
                     /translation="MVDLPWDLEWVESSLQEDLLGYHQYYPMGAGHGVDEEHVERFSGV
                     LPESVLYVWRRFGFDGFADGRFWITDPLVWAPVVDAWVEGTALPFPDQKWWCLNRTAMG
                     DMKLWGEISGPALKIDPILGTLRPSAGSARRMSDPVKRERMGCTVFTSPLKDVFEDEAT
                     GRLVVDEAIERLGPVGEGQLYGFTPAYCFTGRMEARLLGVEDAIAHLVFLAQAQDHQLV
                     EDFSAATAQIAAQIATDDGSDGGGSGGSGGSG"
     assembly_gap    3950..5115
                     /estimated_length=1166
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     CDS             complement(5185..>7303)
                     /codon_start=3
                     /gene_functions="other (smcogs) SMCOG1037: heavy metal
                     translocating P-type ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006547766.1"
                     /locus_tag="HMPREF9062_RS02040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0443"
                     /product="copper-translocating P-type ATPase"
                     /protein_id="WP_009748346.1"
                     /transl_table=11
                     /translation="TRIGASQATRAADLRGRLIVSLILSIPVMAISMVPALQLPGWQWL
                     VAAMALPVATWGAWPFHKAAFGALRHGAFTMDTLVSLGVIAATAWSLWALIWGGAGHIG
                     MRMTMELMPRHQGHAAHMYFESAAWVTTFLLAGRYAEARAKYRSGDALRALLELGAKEA
                     VRVRLASPSGSTDAIDVLDDDGAPRSDAIRTEERIPIDELRTGDLLAVRPGEKIATDGV
                     VVEGRSAVDASMLTGESVPVEVGVGDAVTGATVNTSGSLLVRATAVGEGTTLARIGAMV
                     TAAQAGKAPVQRLADRISGVFVPAVLIVSAATFIAWLALGHPAQHAFMAAVAVLVIACP
                     CALGLATPTALLVGSGRAAQLGVVIKGPEVLESTRALDTIVLDKTGTVTEGSMSLDAAR
                     DITVVSGEAVRDTTRVLTLAGAVEAASEHPVAAAIARAARNVEDGGGGPPRVWDFVSHE
                     GRGVTGTVSLDGVERDVAVGRPAWLVERGIEVPAEADDAIAAAQSTGATAVVLAVDGAA
                     TAVLAVRDTVRPSSAAAIKRLRSLGVRPVLLTGDNARAAAHVAEQVGIAAEDVRADVLP
                     GGKRDVVAELQQRGHVVGMVGDGVNDAAALAQAGTRGLGFAMGSGTDVAIEAADITLVR
                     ADLDAVVAAIRVSRATLRIIKQNLFWAFAYNVAAIPLAAAGLLNPMIAGAAMACSSVIV
                     VTNSLRLRRAAR"
     gene            complement(5185..>7307)
                     /locus_tag="HMPREF9062_RS02040"
                     /old_locus_tag="HMPREF9062_0443"
     assembly_gap    7308..7613
                     /estimated_length=306
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     gene            complement(<7614..8039)
                     /locus_tag="HMPREF9062_RS02045"
                     /old_locus_tag="HMPREF9062_0444"
     CDS             complement(<7614..8039)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017177912.1"
                     /locus_tag="HMPREF9062_RS02045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0444"
                     /product="heavy metal-associated domain-containing protein"
                     /protein_id="WP_009748347.1"
                     /transl_table=11
                     /translation="MSRAADSPPIDATTAPTSAVDLAIGGMTCASCVARVEKKLSKLDG
                     VTASVNLATESARIELTAPVTDDELVNAVARAGYTATVTAHRTPLPTSPDAEAGTGAET
                     PCEAPAGSRAVPAPADAAGRPAGDAERPTNGESAPAEA"
     gene            complement(8198..8461)
                     /locus_tag="HMPREF9062_RS02050"
                     /old_locus_tag="HMPREF9062_0445"
     CDS             complement(8198..8461)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008732393.1"
                     /locus_tag="HMPREF9062_RS02050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0445"
                     /product="heavy-metal-associated domain-containing protein"
                     /protein_id="WP_009748348.1"
                     /transl_table=11
                     /translation="MSEFTADGTDRTTTLKISGLTCEHCVAHVTEELEALPGVKNVSVI
                     LNKGGQSVATVVSDVVVDDAALAAAVDEAGDYVLDAVERDAV"
     gene            complement(8497..8778)
                     /locus_tag="HMPREF9062_RS02055"
                     /old_locus_tag="HMPREF9062_0446"
     CDS             complement(8497..8778)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010612815.1"
                     /locus_tag="HMPREF9062_RS02055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0446"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_009748349.1"
                     /transl_table=11
                     /translation="MAGYTGTKDDYLKRLRRIEGQVRGISRMVEEDTYCIDVLTQIAAA
                     TKALQAVSLGLLEDHMSHCVIHAAQSSDAEGQAKIREASDAIARLVRS"
     misc_feature    8813..8828
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: strong, score: 30.1"
                     /tool="antismash"
     misc_feature    8813..8829
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 25.01"
                     /tool="antismash"
     gene            complement(8905..9585)
                     /locus_tag="HMPREF9062_RS02060"
                     /old_locus_tag="HMPREF9062_0447"
     CDS             complement(8905..9585)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010612812.1"
                     /locus_tag="HMPREF9062_RS02060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0447"
                     /product="response regulator transcription factor"
                     /protein_id="WP_009748350.1"
                     /transl_table=11
                     /translation="MNSLTTPDPDRIGVVLVDDDAMALTCLESYFDPVEDIRILLATRS
                     ARQMMEALESSRVDVLITDVHMESMDGMKVAREVLRVSPGTRVILLTTVDTDDTLIQGL
                     SAGASGFLLKSAPAEEILSAVRTVHSGAKVVAPMSTARLIDYVLASAHTEDGSVTFSDR
                     ERDVLHMLCEGASNRRIASRLSISEATVKSHVSVLLQKTGTRSRLEIVVWAFRHGYAAT
                     GRTA"
     gene            10001..11356
                     /locus_tag="HMPREF9062_RS02065"
                     /old_locus_tag="HMPREF9062_0448"
     CDS             10001..11356
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017194248.1"
                     /locus_tag="HMPREF9062_RS02065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0448"
                     /product="YcaO-like family protein"
                     /protein_id="WP_034253534.1"
                     /sec_met_domain="TIGR03604 (E-value: 1.4e-116, bitscore:
                     386.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 8e-62, bitscore: 207.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRSVLTEEVAPSLARAAALESPVGLVSRCAELAPAPGEPAFSIW
                     TGLLDDPSAALRSQRTWNHRPESGNFDGAGGAIDPRLARHIAIVESLERYSSCSWAEEE
                     LIWDTPAGLGDAAVGPDCWPACSPTELADPRCGLIASDPRVPLRWVRGWSLTRGREVFV
                     PAILVYLNFPVRTPSERFTNPVSTGTAAHSDLREAVLGGLLEVVERDAIALTWLQRLRL
                     PKVVVDIGDLGPDVAEYHRVGTSTELTVHLRDATTDYGIPTLYAVQTSEADTELAQVVA
                     ATCDLDPQRALAKIHRELASLRIALRSHARSPRAQEVTGQDLTVVGGALADAAPSMRHV
                     FDFLLDGPRPAHRLADTGAAAVRNRRTDPLERVVHALEKVGSEAIVVDITTDEARQVGM
                     HVVKALIPQAVPLSFSQHARYLATPRLYEAPRAMGLTVHDEADINPVRQPFA"
     gene            11406..12119
                     /locus_tag="HMPREF9062_RS02070"
     CDS             11406..12119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009232839.1"
                     /locus_tag="HMPREF9062_RS02070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_034253537.1"
                     /transl_table=11
                     /translation="MSTAAELTGQPVGRPARQQVPAEQPVTAYLPQGGFGHAVAHRLAS
                     KRDIVLPVDDGLTDAAVPYADRLVLIADPDRITLRKALDDLSFTRGLPSVGLELSPTEL
                     RCGPLVVPGRTACYRCYDRRRRQHGRTPVPETLEALEQGYAHHHVVIGAGLVMLALDVL
                     DRDPADGTAGASDVDELGGRVWTVDLVAGATSLARTVATDRCETCSARYAARRSGTEEL
                     ARLLPSRRKEAVRRG"
     gene            12112..13971
                     /locus_tag="HMPREF9062_RS02075"
                     /old_locus_tag="HMPREF9062_0449"
     CDS             12112..13971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009406741.1"
                     /locus_tag="HMPREF9062_RS02075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0449"
                     /product="bacteriocin biosynthesis protein"
                     /protein_id="WP_009748352.1"
                     /transl_table=11
                     /translation="MADATGSAASTMRAGDVGRAARNDLQFRIPRKPAVRRGVRMRLDD
                     GAWVLDGGRKNQTLGGRFAREHLGALLQACDGTRTLAEIGEATGIGPQGAFEAVCLLWT
                     GGILEEGGTEPLPDPQPAPELACLLSRLGDSTGVNDSWQDAARRLAAARVAVLGDAGLA
                     EELARALEPTLTARSDVAPEPDDTLAVVVETDAAPTADAARRCWTLGIPLLRVRAEQDA
                     VTVGPYVDPGFSPCLECATAGEPALEPPPGPHRRGFVAGLAARAVAALVSRATITHLPG
                     DARRTDLNTFTYTDRPVVTRPGCPVCSVAGGSSAPIAPSAPVGARYEQSVAIPPAAFVD
                     SKGHQQHYKPSNLRLQREFRDWPACPRTPLPAADLKRLERPWSSTGRDASARRVSDAAA
                     SDTPADRGPTRSVVRPAGPTLVELATVLALAVGVREPTPPQARTSADSPTSTSKMRRWT
                     AAGGNIGSVTAYVLAPARSEADGGSGAGRADRASDRADGPIGGAADESGPLTPGVHAYI
                     ESDHTLALIGPPAEIPDDAGVRLVLTGNVDKVARKYLSFALRIAIQDCGCSLEVVRLVA
                     RCLDLPLRTRARWDERELAAAIGTDPTREPVFAVIDLGGNRAL"
     gene            13961..14737
                     /locus_tag="HMPREF9062_RS02080"
     CDS             13961..14737
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003780689.1"
                     /locus_tag="HMPREF9062_RS02080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_034253540.1"
                     /transl_table=11
                     /translation="MRSDYETMREIINGFSDPDGRPTSDGLAAWRARRPLKLAVPHMLD
                     PQADEPYPYDLRTTFARRSSTTDYAPEPLDAEPLLASVQAALVEDAGAWEDDATPPDPP
                     DPPDGTAAAEAAGATAVHLEPFVVLLRSRGAPPGVYRIRTNGTDLVANPPDPEQIEGMT
                     VQKEFARAGAIVSVAANLDEADAWAGAHGYRHAMARAAAVIYSVHLRSAARGLTGTVFA
                     GLSPSAVRHLLDSDGVGRHQMFAATVAVPPSVVPPS"
     gene            14875..15048
                     /locus_tag="HMPREF9062_RS12780"
     CDS             14875..15048
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009232842.1"
                     /locus_tag="HMPREF9062_RS12780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiocillin family RiPP"
                     /protein_id="WP_156789931.1"
                     /transl_table=11
                     /translation="MTTTIDLTLTDSDFGIEELPEGNALGCAFCGACASCPSCAASASC
                     PSCAASASTTSC"
     gene            15137..16303
                     /locus_tag="HMPREF9062_RS02090"
                     /old_locus_tag="HMPREF9062_0451"
     CDS             15137..16303
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017177810.1"
                     /locus_tag="HMPREF9062_RS02090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0451"
                     /product="PqqD family protein"
                     /protein_id="WP_009748354.1"
                     /transl_table=11
                     /translation="MTTTSQIPRLRRGVKLIVGMDDQPMLFDTDAGTYHRLGAAAAVII
                     NQFDGARSLPAILDQLPQNIDAAGRQRITRLVDYLRSKSLLEGGPPLRTRPSERARKRV
                     DGRHVAPPHVGRHEQIQPPRWSGGWMLPRFMLIRTYRRAVAPVAAALHHLPVRTLSGLF
                     LLAAAGGYAAGAASLINLSGGPRPPARVFFIAVAIQLVSIVGHESWHAIVAGYLGTPVR
                     GLGVAFMFWVLPIAYVDRTDSYRARSRLGRAMLAIAGVCSDGVVCGAEAAVAVASSGTV
                     RQVALTLCAFQLTMLITNLNPLTQSDGVATVEALTGSVNLRGRSTLILRCAVTRTPLPP
                     ALARMRPTVRAAYAVYGLLCVLLGVVGTVVSVTWVLFIVIGIVKGLLA"
     assembly_gap    16384..16433
                     /estimated_length=50
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
     misc_feature    16498..16512
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     gene            16514..19051
                     /locus_tag="HMPREF9062_RS02095"
                     /old_locus_tag="HMPREF9062_0452"
     CDS             16514..19051
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003784907.1"
                     /locus_tag="HMPREF9062_RS02095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0452"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_009748355.1"
                     /transl_table=11
                     /translation="MLPTLVRLGGLPACAVPRPQNALIAALEEVRRLDRETERAAGRLL
                     DPLYELIPLLDRDERRAVLHAKRKVFQSRASGLSARVRAGLPSDIGAMLIDWDRLMAQR
                     RNARTRLDKAVAADLENSRALLAHSLDDPDYLRSVAIAAPALVSTLARRGRRLDDPRVL
                     RTLYSLASRTALKTSPFSGLTTVSEAGRPARGRRRCTVALHLAHGILMAVARDLDPAGH
                     LRLEAATVRDDVVPAGTDKGEAAGLATDPVGAADAARPATGPALTVVAEHDYANGMIFR
                     REEIQPARWLAAAHDRLTGGLTDAPPVSVREAVRLVGGRDPRLRLRRLLASGAVRPHPP
                     WARGEDPFPALAATLSESQRGAWAEDLGRLVELGRAVTVEDGTDRAERLADAGRLAQRV
                     FPDHELGARPAGLLYEDCESRGERTDPMEQVTFRRDVETLAGLVDPWVTRSRIYDLMVE
                     RYVARYGRGGVCEDPLAFFMSLAHAPDGDAQMLRAAGQDLASGPDPERAAMPGGVSASP
                     RHMGAYLQPVVVGRRASADDNRTDEPAGAGSGGRLTVVNAFTNGNGALQARFHRLLGRQ
                     YRQRLARGIRAAWGIDRVLEIQVSTDCNTAQAVSCGVLPPLGLPGEPESAQAVPLSSLR
                     LAHDPRTDTLFLADARGPVGLAYLGLISQHRLGGYLAWLVLLSDPWARLAPMADHWTSR
                     RRRMDPLPDEPVHSPRTVHGRLVTRRQSWIFPAGHVAGLLDRDSAATLVRVASLRERWG
                     IPAEVYVHQHRGPDAVSRAATFDEHKPRYVDLRSPASLLALHGWIDPAAEHLSLIEALP
                     ARDQQAGVTPSGRTTALEYLVGLQWPKNDGDVR"
     gene            19048..20001
                     /locus_tag="HMPREF9062_RS02100"
                     /old_locus_tag="HMPREF9062_0453"
     CDS             19048..20001
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009234588.1"
                     /locus_tag="HMPREF9062_RS02100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0453"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_009748356.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.3e-19, bitscore:
                     68.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALDDGVDGIRDTDGMAVSSGPDGTAAVGRGQQIDWLYARIYCA
                     GGDDTDALMPRLAHWLDAVRAHWPIRSAHFLRFVDLRGHHLRLRVQAAPDTLDEVFARL
                     DILDAAARRAPVRALERLVSDPLTSGGGSGRPGVACAVYGPEYAKYGGPKGAEGAESHF
                     DISSRWCLDNRVWKVPRPVGRVGLVARLLANAAVAGPLPADELLAAHLRMWGYRLPERL
                     RDGAALGAVVRQVLEFPLNGTPGWEHADELTSQVADDAARTVGRIGAGAGGRRALDLLH
                     IDANRLGVNPAEECVAGVCARYLLGGLGVAGASARG"
     gene            complement(20124..20435)
                     /locus_tag="HMPREF9062_RS02105"
                     /old_locus_tag="HMPREF9062_0454"
     CDS             complement(20124..20435)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF9062_RS02105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF9062_0454"
                     /product="hypothetical protein"
                     /protein_id="WP_009748357.1"
                     /transl_table=11
                     /translation="MSHNDTQATDQPNLLIKKASILAPVVAQMKNHKLLASYQNNLVRR
                     IQTDGLRPGLTYGVISVRGLMLGTAGALYALNAIHHSALPNPLLLEPPLTNEPGTNNL"
     gene            20512..21654
                     /locus_tag="HMPREF9062_RS02110"
                     /old_locus_tag="HMPREF9062_0455"
     CDS             20512..21654
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="HMPREF9062_RS02110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0455"
                     /product="sensor histidine kinase"
                     /protein_id="WP_034253543.1"
                     /transl_table=11
                     /translation="MVSVSRARWQVDAASAVAAVLVCLGLGVSGQPDWLWSAVMAAVLV
                     LRRTLPWVFASAVAAISCAHLLVDSRLLFPGDLLVLVAVYTVASYASVRARRVGLVTGV
                     VYVGVLLFRVVLGEGVRSSPRGFSPVIVIVACMIASWSVGLVERQRREALAEAERRRVL
                     AEHDAEARIRLAAYEEHERMSNDIHDVLAHTLTGIIVQAESGRAISVDGEPRELFTRIS
                     QTGRTALDEVRGLLASYEESPGTQPSPGLEDLGSLLATFEQAGLNVRRVDSGERVDLPQ
                     GMALAIYRVVQESMTNALRHGSTRQAKLTLEWTSQELTVTVVNPLKDDVDLAAVEHCRG
                     LSGIRRRCALYGAQAQIRAGEEFTVKTVWPLAPGPAGKVS"
     misc_feature    20944..20946
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21651..22379
                     /locus_tag="HMPREF9062_RS02115"
                     /old_locus_tag="HMPREF9062_0456"
     CDS             21651..22379
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="HMPREF9062_RS02115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0456"
                     /product="response regulator transcription factor"
                     /protein_id="WP_216584402.1"
                     /transl_table=11
                     /translation="MSSTSQVITVLIVDDQGLVRDGFTRIVDAQPAMRVVGVASNGREA
                     IALARARRPDVILMDVRMPGVDGIEATRTIVQEDESIRVLGLTIFDNDAYAVRMLKAGA
                     TGFVLKDSTADQLVDAIRSAHHGTLTVAPATGRRLLRRLVEHEAPRRGAPALRELTDRE
                     ATVFRLVTSGMSNLEIAQHLCISEVTVKSHVGRVLSKLGARDRVQLVLWAHRNGVLPVS
                     SESAGGPEGPGGGDASDRGA"
     gene            22525..23424
                     /locus_tag="HMPREF9062_RS02120"
                     /old_locus_tag="HMPREF9062_0458"
     CDS             22525..23424
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017177079.1"
                     /locus_tag="HMPREF9062_RS02120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0458"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_009748361.1"
                     /transl_table=11
                     /translation="MSAAITTSNLTKRFKTHVAVDSLNLDVPQGAIYGFLGPNGSGKST
                     TMKMLLGLTRPTEGEIRVFEQDLTPASRTRMLPSIGSMIEAPPGYGHLTGLENMRIVQD
                     MLDLSAVQIEHALETVRLTEHKNKLVRNYSLGMKQRLGIAMALARDPALLILDEPTNGL
                     DPAGIEEIRTLLIRLAGHGITVMVSSHLLDEIDKMANVLGILANGRMIFQGTRDQLFEH
                     SIPDLVIETPDARAALAQGITATPIAEGIRVSGLGKDQTAELVYRLAVAGVPIHGVRRV
                     QQSLEDVFMDLTGRGGLL"
     gene            23421..24173
                     /locus_tag="HMPREF9062_RS02125"
                     /old_locus_tag="HMPREF9062_0459"
     CDS             23421..24173
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017195127.1"
                     /locus_tag="HMPREF9062_RS02125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0459"
                     /product="ABC transporter permease"
                     /protein_id="WP_009748362.1"
                     /transl_table=11
                     /translation="MNRAIRLELRKMRRLRTGLTTTALVLAVVALSSISLFSGSTRRTF
                     DDPEAMPWATLMMSYAFMAAMTSPILTAVLASRQTDIEHSGAGWQLAATAGYSPGALCR
                     AKLAALSLVLTPAVIGQTFLVLAVGALVGIHVPINAGPWVGYTLLLLLVDIAFLALHIW
                     LACVGENQLMSVGIGMLGAFLAVFTLLMPGAVARFIPWGYYAMISYVGQQGDNIIYITP
                     DYVWIAGFLLLVGVVFIQMTRRLDRTER"
     gene            24179..24925
                     /locus_tag="HMPREF9062_RS02130"
                     /old_locus_tag="HMPREF9062_0460"
     CDS             24179..24925
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="HMPREF9062_RS02130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0460"
                     /product="ABC transporter permease"
                     /protein_id="WP_009748363.1"
                     /transl_table=11
                     /translation="MFRAELIKLKRSSIWLIALALPLLAVITGTINLANNPDALNAGWA
                     SFTSQVTLFYSLLFYSMGIALLTATAWRMEHRGTNWNLLLTGTRRPARLVLAKVVVIAV
                     PVAFMQLVLVGGTVASGVVVLRLDGAVSWQFAAVGALSVIVALPLIAFQSMLSMLLKSF
                     AVPVAICLLGCVASIAAVTSDALHPLSYALPQALNTRTLNLGSTAFAGSGGLTGADVAP
                     LLGAALVLTATAIGLTTVAMRVIKLR"
     misc_feature    24755..24757
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(25538..26983)
                     /gene="purB"
                     /locus_tag="HMPREF9062_RS02135"
                     /old_locus_tag="HMPREF9062_0461"
     CDS             complement(25538..26983)
                     /EC_number="4.3.2.2"
                     /GO_function="GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA]"
                     /GO_process="GO:0006188 - IMP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="purB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003784905.1"
                     /locus_tag="HMPREF9062_RS02135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0461"
                     /product="adenylosuccinate lyase"
                     /protein_id="WP_034253546.1"
                     /transl_table=11
                     /translation="MVDLSTVSPVIALGPLDGRYRAVAAPLVNHLSEAALNRARLAVEV
                     EWLIHLTDHHVLPGAPRLSESEKAYLRGTVDSFGAAEIAELAEVEAVTRHDVKAVEYLL
                     KRRLDAAGDDPSVSGADGGPTVLPTVHEIVHIFCTSEDINNLAYALTVRSAVKEAWLPA
                     AHGLIADLTAMAREHAGAAMLARTHGQPATPTTLGKELAVLARRLTRQVRRVESAEYLG
                     KFNGATGTYGAHVVAVPEADWQSVSRTFVEGLGLVWNPLTTQIESHDWQAELYCDIARF
                     NRVAHNLATDVWSYISLGYFRQRLATQGSTGSSTMPHKVNPIRFENGEANLEISCSLLE
                     TLAATLVTSRLQRDLTDSTTQRNIGTALGHSLLAIDNIRRGLAGLDVDAARLEADLDAT
                     WEVLGEPVQQAMRAASVAGATGMADPYERLKKLTRGKRVTPEAMRAFISGLGMPDDVEA
                     RLLALTPATYTGLAARLVGHLDD"
     gene            complement(27373..28695)
                     /locus_tag="HMPREF9062_RS02140"
                     /old_locus_tag="HMPREF9062_0462"
     CDS             complement(27373..28695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008733894.1"
                     /locus_tag="HMPREF9062_RS02140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0462"
                     /product="aminopeptidase C"
                     /protein_id="WP_009748365.1"
                     /transl_table=11
                     /translation="MIDPRSHAVDPAWVDTRNAAVSADPAARVAGNAVATTDVEKLTVD
                     RRVIASIDTSVSDLIPDAIVTDQKRSGRCCAFAGLNVLRASLIEELTVDSLELSQNFIY
                     FHDKLEKAAAFLHRAVDDAERPLSDREVVETLREPISDGGWWPEFARLVSKYGMVPHAA
                     MPDTHSATDSDAMNAHLATVLRRAALRLRAAVAAGADPEPVRSAAMEDVHRLLAIHLGT
                     PPTEFMWQYRDKDKVFHRVGTLTPREFAERYAAGLEEFVVVAHDPRPEIPVNTRFGIER
                     TDLMVGEPTQEHVTAALDVLKAAAIAAIQDGEPVWFACDVAKQREKKSGVWDAALHDYE
                     GLYGVELSMTKAERLVARESALTHAMCLTGVDLLDNAPRRWRVENSWGDKLGEKGFHTM
                     NDSWFDEYVYQVVVRASRLPDEVRAALEVEPVMLPSWDPMF"
     gene            28790..29413
                     /locus_tag="HMPREF9062_RS02145"
                     /old_locus_tag="HMPREF9062_0463"
     CDS             28790..29413
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /GO_function="GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA]"
                     /GO_process="GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008733897.1"
                     /locus_tag="HMPREF9062_RS02145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF9062_0463"
                     /product="bifunctional 2-polyprenyl-6-hydroxyphenol
                     methylase/3-demethylubiquinol 3-O-methyltransferase UbiG"
                     /protein_id="WP_034253549.1"
                     /transl_table=11
                     /translation="MNERQMQWEARYAAVDRLWSGDPNDWLPELALGWEPGRALDLGCG
                     EGADAVWLAEHGWDVTGLDLSATAIARMRARARDRGLAGRVHGLVLDATRERLPAGPFD
                     LVAAFYVHGGPMPGSLDLVELLTRGAVLAAPGGRVMTAVHCVNPPWHRHHARTYTPAEL
                     LAGLAGATKGWQVEVAQERWREVPGPDGEAGRRSDAVICLRRPV"
     gene            29532..>29926
                     /locus_tag="HMPREF9062_RS13075"
     CDS             29532..>29926
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF9062_RS13075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_034253552.1"
                     /transl_table=11
                     /translation="MNAHESGPPDDAASPGRGAEHDSPGRGLQPEAGPGDEIAGPGADH
                     VDGVRSGNGAALGSDPASEPDPVPGWIADLVPVADDARAILLADRVVLAAGVPLALVLG
                     WAGARRDVGHLPIWAGALMAAAAAAVVL"
     assembly_gap    29927..29976
                     /estimated_length=50
                     /gap_type="within scaffold"
                     /linkage_evidence="unspecified"
ORIGIN
        1 caatggcacc gatccccacg tagatctgtc ggctggccca gcgggagcgg atggactccc
       61 aggaccggga agggcctgca tgtccacgca agggtgtagt catgtcgtct ctaatcattg
      121 ggtaccggtg ttcctcgctc acgatagcaa gagcgcgtgg cgggggttga cgggagtcgg
      181 ggtcatgatg cccatgatcg tctacaggtc cctgctccgc tgaaggtgcc gcagactcag
      241 ccaaccggcc gggatgggga tccagaaggt gaccaggcgg tagacgatcg cagcggacag
      301 cgccacaccg ctcgggatgc cggccgtgac gagcccggcg gtcagcgcga tctcgaccgg
      361 gccgatgccg ccgggagagg gcaccacgga ccccaccgtg ttggaggcca ggtaggtgat
      421 cgccagaatc gagaagggga gcgtgtaccc gaaggcccac aggcttccgc cgaaggcgag
      481 gacgtagctc aggctgagca ggacggtgcc ccccacgccc agcgccaggc gcagcgggtt
      541 cgacatgatc cacaccaggc gcggccacac ctgccgatac gtgggctcga tcttggcccg
      601 cacccaggtg cgcacccggg gcacgaacag cgccgagccg accacggcca cgagcacgat
      661 ggcacccagg acgagccagt ccgagggcag ggtcaacccg gtggactgcc ccgtcatcgc
      721 agccaggatg atgagcagaa caatcgtgac gaggaactgg acgacctgga cgagcgcgac
      781 cgtggccacg ccgatggggg tgggcacacc cctgcgagtc agaaagcgca agttgatggc
      841 ggcaccgccg accccggcgg gggccacgag ggagaccacc gcgccggcca ggtgcacctc
      901 ggtcgatttc cacacgctca gacgcaccgg actgaaggcg accagtgcga tccccgcgcc
      961 cagataggtc gccagggaga agacgacggc gccgagaatc caccacgcgt tggctgcggc
     1021 gacagcggcg ctgatctggc tgaaattcat gcgcgctagc agcgtccaca gcgcgacgag
     1081 cccgacgacc gccatgacga cggtccgcgg ggagaaccgg gtgagcttgg cgggctcggc
     1141 gtgcgcggtg ggcgtcaggg cgacgagagc gtcgcgcagc tcctggagga gccggccgcg
     1201 ctgttcgccc agggcgtcgc gggtcgtcgc gggcaggacg acgcgctgga gcatgggcgc
     1261 gatggaggcg atctgaggcg tgctcagcga ccgcgaggcc gcggcgatgg ctcggtcgac
     1321 gccgacgacg gaggccgtca gggcgagagt ctgggcgaga tccacgcggc gggacagctc
     1381 ggaggagatc gtctcccccg agtcccagtc cagcagccac acgcatccgg cgacgtcgac
     1441 gaccacactg gaggagtcga tggcgcggtg agccaggccg gcggcgtggg cccggcccag
     1501 ctgttcccac agctgagcca ggacgtcgtc ggaaacctcg tccagatcgc ccagggcgcg
     1561 tgcaccgatg acatgatcgg ccaccagcag aacggattcg tcggcctccg ccatcccgaa
     1621 cagcgccggg gtgcgcaccc gggcacggtg ggcctccaga gtcatgagag ccgcgtgctc
     1681 ggccgccgag cgcacggaca ggtcgcgctc gggggagagc cccttaatgc gaatgcggtc
     1741 ccacagggtg gagacgaagc cggcgacctg gctgtcggtg tccagaaccg tcacgtcccg
     1801 gcggataccc gtggcgtccc acacggcgta gagcctgtgc accgagggcc ggcccacggt
     1861 cagggcggcc gaggaggcct cggtcacaat cgcctccagg tcgacatcgg tggcggtggt
     1921 gatcgtggcc gtctcctccg gatgtagcgc ggcggcgacc tcggcgggct cgttcgggta
     1981 ctcagtcaag tcgagccggg gcccggcatc atcgaggtcc ggcatggcgg ccggtatcgt
     2041 caacggattc tcccgaacct gctcggtgta tcccacaggc gtatcggtca cgactgtcca
     2101 ggcctttgcc gccggggcgc ggtccatgcg caccacccgt acggcgtcga tgccggcgcg
     2161 gcgcagcgcc cgcacgagcg cggtgccgtg ggcgcgccgg tcctcaacgc cgaacccgta
     2221 gcggatcgcc agacccagca cgcgtcccag caggacggac ataacggcgc cgggcagggt
     2281 cagtgcgctg cgcagcacgg ccaagccgat gatgacccac agggccgtcc agccgcggcg
     2341 caccgcatga gaggcgcgtc gctccccggc accggtcagc agaccggcca gggtggcgaa
     2401 gaccgtggag atgccgacct tggcggtgcc cgaggcggtg accgtcagac ccgagatgat
     2461 ggcggagggc gcccaggagg tgacggcggc gagcacggcc caggccagga gaaatccgcc
     2521 gataccgccc agaatcgcct ggccggccgt gcgccaggaa cggcgcagga ggctcgccag
     2581 gacgacggac acgggtacga ggaaggtcgc caggccctcg acggtctgga gggggaagac
     2641 gaggatctga cgcaggacgg ctgcgagagc attctgcaca tcgagggtga cgccggtggt
     2701 cgtctcgtgg gcgtaggccg ctagaatgag catggaggcc gagccaatgg cggccaggac
     2761 aagatcgagt aggtcctcgg tgcggcgcag gcggtgaggc gccgcatcca ccagaagggt
     2821 ggtcgaacgg gacctcgacg gagctggaga aggctgctgt gtcgggacgg cgggagtgac
     2881 gccgatccga ggaatgccga cgggcgaggt cgcgggcgct gattcgacgg tggtgtcggc
     2941 gtcctgcgag cctggaggca ggtcggatgt catgttcaga agtctacggg cggggcatgg
     3001 gacccacctc cgcctcgggg aggacgcgcg tctgcggccg tggaaggaaa aagactttcg
     3061 agatcagcgc gttccgacgc ggggaagggt gagtcggtgg cgtgggcgcg gggtgttgtt
     3121 gtgtgtggtg tcggtgcggg gcggtgtgtg gctgacggtg tgtggtggtg gttgttaggg
     3181 tggggtcatg gttgatctgc cgtgggatct ggagtgggtg gagtcgtcgt tgcaggagga
     3241 tctgctgggg tatcaccagt attatccgat gggtgcgggg catggggtgg atgaggagca
     3301 tgtggagcgg ttctcgggtg tgctgcccga gtcggtgctg tatgtgtggc ggcggttcgg
     3361 gttcgatggg ttcgctgacg gtcggttctg gatcactgat ccgctggtgt gggccccggt
     3421 ggtcgacgcg tgggtggagg ggacggccct gcccttcccc gaccagaagt ggtggtgcct
     3481 gaaccgcacc gccatgggcg acatgaagtt gtggggggag atctccggcc ccgccttgaa
     3541 gatcgacccg atactgggca cccttcggcc cagcgccggc tccgctcggc gtatgagcga
     3601 cccggtcaaa cgcgagcgca tgggctgcac cgtcttcact tcaccgctta aggacgtgtt
     3661 cgaagatgag gccacggggc ggttggtggt ggatgaggcg atcgagcgtc tgggtccggt
     3721 gggtgaggga cagctgtacg ggttcacgcc ggcctattgc ttcaccgggc gtatggaggc
     3781 ccgtctgctg ggcgtggagg acgctatcgc tcatctggtg ttcctggccc aagcccagga
     3841 ccaccagcta gtcgaagact tctccgcggc gaccgctcag atcgccgccc aaatcgccac
     3901 cgacgacggc agcgacggcg gtggctccgg cggctccggc ggctctggcn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5101 nnnnnnnnnn nnnnngctga accagcccgt agaccgctag cggtcggccg gagatccggt
     5161 ggtgcggtgg ggtggcggct cggctcagcg ggccgctcga cgcagacgca gcgagttggt
     5221 caccacgatg acgctcgagc atgccatggc ggcccctgcg atcatcggat tgagcaggcc
     5281 cgcggccgcc aacgggatcg cggccacgtt gtaggcgaag gcccagaaca ggttctgctt
     5341 gatgatgcgc agcgtggcgc ggctgacgcg gatggccgcc acgacggcgt ccaggtcggc
     5401 gcgcacgagc gtgatgtcgg cggcctcgat ggccacatcg gtgcccgagc ccatggcgaa
     5461 accgaggcca cgggtgccgg cctgggccag ggccgcggcg tcgttgacgc cgtcgccgac
     5521 catgccgacg acgtgtccgc gctgctgcaa ttcggcgacg acgtcgcgct ttccgcccgg
     5581 cagcacgtcg gcgcgcacgt cctcggccgc gatcccgacc tgctcggcca cgtgcgcggc
     5641 ggcgcgggcg ttgtcgccgg tgagcaggac cgggcgcacg cccagcgaac gcagccgctt
     5701 aatcgccgcg gccgagcttg gccgcaccgt gtcccgtacg gccaggacgg cggtggcggc
     5761 cccgtcgacg gcgaggacga ctgccgtggc gccggtgctc tgggcggcgg cgatggcgtc
     5821 gtcggcctcg gccggaacct cgatgccccg ctcgaccagc catgccggac gcccgacggc
     5881 gacgtcgcgc tcgacgccgt cgaggctcac cgtgccggtg acaccgcgcc cctcatggct
     5941 gacgaagtcc cagactcgcg gcggcccgcc gcccccgtcc tcgacattcc gggccgcccg
     6001 ggcgatcgcc gccgcgaccg ggtgctcgct ggccgcctcc acggcgccgg ccagggtgag
     6061 aacgcgcgtc gtgtcgcgca ccgcctctcc gctcaccaca gtgatgtctc gggccgcatc
     6121 caggctcatg ctcccctcgg tgacggtgcc cgtcttgtcc agcacgatcg tgtccagggc
     6181 gcgggtggat tccaggactt cgggcccctt gatgacgacg ccgagttggg cggcgcgccc
     6241 cgagcccacg agcagggccg tcggtgtggc caggcccagc gcgcacgggc aggcgatgac
     6301 gagtacggcg acggccgcca tgaaggcgtg ctgtgccggg tggcccaggg ccagccaggc
     6361 gatgaaggtc gccgcggaga cgatgagcac ggcgggcacg aatacgcccg agatgcggtc
     6421 ggccagacgc tgaaccgggg ccttgccggc ctgagcggcg gtgaccatgg ccccgatgcg
     6481 ggccagggtc gtgccctcgc cgacggcggt ggcgcgcacc agcagcgaac cggaggtgtt
     6541 gacggtggcg ccggtgacgg catcgccgac cccgacctcg acgggcaccg attcgccggt
     6601 gagcatggag gcgtccacgg cggagcggcc ctcgacgacc acgccgtcgg tagcgatctt
     6661 ctccccgggg cgcacggcca gcaggtcgcc cgtcctcagc tcgtcgatcg ggatgcgctc
     6721 ctcggtgcgg atggcgtccg agcggggggc gccgtcgtcg tcgaggacgt cgatggcgtc
     6781 ggtcgagccc gacggcgagg ccaggcgcac ccgcacggcc tccttcgcgc cgagctcgag
     6841 cagggcgcgc agggcgtcgc cggagcggta tttggcgcgg gcctcggcgt agcgcccggc
     6901 cagaaggaag gtggtgaccc aggcggccga ttcgaaatac atgtgcgcgg cgtggccctg
     6961 gtgacgcggc atgagctcca tggtcatccg catgccgatg tgcccggccc cgccccagat
     7021 gagcgcccac aggctccatg cggtcgcggc gatgacgccc agagatacga gggtatccat
     7081 ggtgaaggcg ccatggcgca gggccccgaa ggcggccttg tggaagggcc aggctcccca
     7141 ggtcgccacg ggcagggcca tggccgccac cagccactgc cagccgggca gttggagggc
     7201 cgggaccatg gagatcgcca tgacggggat ggacaggatc aggctgacga tgaggcggcc
     7261 gcgcaggtcg gcggcccgag tcgcctgtga ggccccgatg cgcgtggnnn nnnnnnnnnn
     7321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnggcttcc
     7621 gccggggcgg actcgccgtt cgtgggtcgc tcggcgtcgc ccgccggccg gccggccgcg
     7681 tcggccgggg cgggcacggc gcgtgatccg gccggggctt cgcagggggt ctcggccccg
     7741 gttccggcct ccgcgtcggg ggaggtcggg aggggcgtgc ggtgggcggt gacggtggcg
     7801 gtgtagccgg cgcgggcgac ggcgttgacg agctcgtcat cggtgaccgg cgcggtgagc
     7861 tcgatgcggg cggactcggt ggcgaggttg accgaggcgg tcacgccgtc gagtttggag
     7921 agcttcttct ccacgcgcgc tacgcacgac gcgcaggtca taccgccgat ggcgaggtcg
     7981 acggcgctcg tgggggcggt ggtggcgtcg atcgggggcg agtctgcggc tcggctcatg
     8041 atggatcaca ttcctggact cagctgtaat ggttccgggt gttccgggtg gggtgacggg
     8101 tcggggtgcg cggtgcgtgc cgacccgtca ccgcgggtgc gccggcccgg gccgtcctga
     8161 ggttcgggcc ggcccgggcc cggctggatc ggcctggtca gactgcgtcg cgctcgacgg
     8221 cgtcgagcac gtagtcgccc gcctcgtcga cggccgcggc cagggcggcg tcgtccacga
     8281 cgacgtcgga gaccacggtg gccaccgact ggccgccctt gttgaggatg acggagacgt
     8341 ttttgacgcc cgggagggcc tcgagctcct cggtgacgtg ggcgacgcag tgctcgcagg
     8401 tcaggccgga gatcttgaga gtggtggtgc ggtcggtgcc gtcggcggtg aattcggaca
     8461 tggcgtgctc cttgaggtgg gtgttccggg tggtgctcag gaccgcacga ggcgggcgat
     8521 cgcgtcggag gcctcgcgga tcttggcctg gccctcggcg tcggaggatt gggcggcgtg
     8581 gatgacgcag tggctcatgt ggtcctcgag caggccgagg ctgacggcct gcagagcctt
     8641 ggtggccgcc gcgatctggg tgaggacgtc aatgcagtag gtgtcctcct cgaccatgcg
     8701 ggagatgccg cggacctgtc cctcaatgcg gcgcagccgc ttgaggtagt catccttggt
     8761 gcccgtgtag ccggccatcc gtcctccttg ctctgtcggg gtgctattga atttacccct
     8821 agggggtagg ggtgtcaact gtcgtcatgg cccgcggaga cccgcgaggc gggagtcgtc
     8881 actcaccggc tcccgaccgc ggacctaagc ggtgcggccc gtagcggcgt agccgtgcct
     8941 gaacgcccac acgacgatct ccaggcgaga gcgcgtcccc gtcttctgga gcagaacgga
     9001 cacgtgagat ttgaccgtgg cctccgagat ggatagccgg gacgcgatcc tgcggttgga
     9061 ggctccctcg cacagcatgt ggaggacgtc gcgctcacga tccgagaagg tgacgctccc
     9121 gtcctcggta tgggcggagg ccaacacgta atcgatcaga cgggccgttg acatcggtgc
     9181 gacgaccttc gcccccgagt gcaccgtccg gacggcggag agaatctcct cggcgggcgc
     9241 gctcttgagc aggaaaccgc tggcgcccgc gctcaggccc tggatgaggg tgtcgtcggt
     9301 gtcgacggtg gtcaacagga tgaccctggt gccaggggag acccgcagca cttcccgcgc
     9361 caccttcatc ccgtccatgc tttccatgtg gacgtcggtg atgaggacgt ccacgcggct
     9421 ggactcgagg gcctccatca tctggcgggc actgcgcgtc gcgagcagga tccggatgtc
     9481 ctcaaccggg tcgaagtagg actccaggca ggtcaacgcc atcgcgtcat cgtcgacgag
     9541 cacgacgccg atacgatcgg ggtcaggggt agtcagggaa ttcatagggt ctccttgcgg
     9601 aacatcggaa cgagccgtgg gcggggtgcc cacggctccc cggaagatca cgataaggtt
     9661 acgattcaga atacctgagt agtcccgaat gacggcgctc gcccggtatg tggcgcgatg
     9721 gcgtggcgaa gtcgccccgc accgacccgc tcccccgccc cggccagaag tggccgacgt
     9781 cgccggatcc cacgtagttt aaaggctagc tgtcggtgca ctgcgtcatc ggtgcgtcaa
     9841 agggatgagt cgcatcagcc gaacgacggg aacggcggcc ccgaagagcg cgcgcatagt
     9901 agaccgacgg ccgatgcgga ccgtcgggac cccgggaaga cttccctcca gcggcacgta
     9961 ctggacgtgc cggccctgtc tcaccctgga aggcggattc gtgtaccggt ctgtgctcac
    10021 ggaggaggtc gctccttcat tggcccgtgc ggcggctctc gagtcgcccg tcggcctggt
    10081 ctcccgctgc gccgagctgg ccccggcgcc gggggagccc gcgttctcga tctggaccgg
    10141 actcctcgac gacccctccg cggcactgcg ctcgcagcgc acctggaacc accggcccga
    10201 gtccggcaat ttcgacggcg cgggcggcgc catcgacccg cggctcgcca ggcacatcgc
    10261 catcgtggag tccctggagc gctactccag ctgctcgtgg gctgaggagg agctgatctg
    10321 ggacaccccc gccggactcg gcgatgccgc cgtcgggccg gattgctggc ccgcctgctc
    10381 gccgaccgag ttggccgacc cgcgatgcgg cctcatcgcc tcggacccca gggtccccct
    10441 gcgctgggtg cgcggatggt ccctgacccg cggtcgggag gtcttcgtcc ccgccattct
    10501 ggtctacctc aacttcccgg tgcgcacccc cagcgagcgc ttcaccaacc cggtgtccac
    10561 cggcaccgcc gcccactccg acctgcgcga agccgtcctc ggcggcctcc tggaggtcgt
    10621 cgagcgcgac gccatcgccc tgacatggct gcagaggctg cgcctgccca aggtcgtcgt
    10681 ggacatcggc gacctcggcc ccgacgtcgc cgagtaccac cgggtcggca cctccaccga
    10741 gctgacggtt cacctcaggg acgccaccac cgattacggg attcccacgc tctacgccgt
    10801 ccagacctcc gaggccgaca ccgaactggc tcaggtagtg gcggccacct gcgacctcga
    10861 tcctcagcgc gccctggcca agatccaccg cgaactcgcc tcgctgcgca tcgccctgcg
    10921 cagccacgcg cgcagccctc gcgcccagga ggtcacgggc caggatttga cggtggtcgg
    10981 cggcgcgctg gccgacgccg ccccctccat gcgccatgtc ttcgacttcc ttctggacgg
    11041 gccccgcccc gcccaccggt tggccgacac gggcgcagcg gcggtccgga accggcgcac
    11101 cgacccgctg gagagagtcg tccacgcact ggagaaagtc ggttcggagg ccatcgtcgt
    11161 cgacatcacc accgatgagg cccgccaggt cggcatgcac gtggtcaagg ccctcatccc
    11221 gcaggccgtg ccgctgtcct tcagtcaaca cgcccgctac ctcgccaccc cccgtctcta
    11281 cgaggcccct cgcgccatgg gcctgacggt ccacgacgag gccgacatca atcccgtccg
    11341 tcagcccttc gcctgacgcg cccataggaa gacccacccc gtaggaagac ctggaagatc
    11401 catccatgag caccgcagca gaactgaccg gacagccggt cgggaggccg gcccggcagc
    11461 aggtccccgc cgagcagccg gtcacggcct acctccccca agggggattc gggcatgccg
    11521 tcgcccaccg cctcgcctcg aagcgggaca tcgtcctgcc tgttgatgac ggcctgaccg
    11581 atgccgccgt cccctacgcc gaccgcctcg tcctgatcgc cgacccggac cggatcaccc
    11641 tgcgcaaggc cctggacgac ctgtccttca cccgaggcct gccgtcggtg gggcttgagc
    11701 tgtcgccgac cgaactgcgc tgcggacccc tggtcgtgcc cggacgcacc gcctgctacc
    11761 gctgctacga ccgacgccgt cgacagcacg gccgcacccc cgtgcccgag acgctcgaag
    11821 cgcttgaaca gggctacgcc caccaccacg tcgtcatcgg cgccggcctg gtgatgctcg
    11881 ccctggacgt tctggaccgg gaccccgccg acgggaccgc cggcgcctcc gacgtcgacg
    11941 aactcggcgg ccgggtatgg accgtggacc tcgtcgccgg cgcgacctcc ttggcccgga
    12001 ccgtcgccac cgaccgctgc gaaacctgtt cggcgcgcta cgcggcccgg cgctccggga
    12061 ccgaggagct cgcccgcctc ctgccctcgc gccggaagga ggcggtccgc cgtggctgac
    12121 gcgaccggat ccgcggcctc caccatgaga gccggtgacg tgggccgggc ggcccgcaac
    12181 gaccttcagt tccgcatccc ccgtaagccc gcggtccgcc gcggggtgcg catgcgcctc
    12241 gacgacggcg cctgggttct cgacggcggg cgcaagaacc agaccctcgg cggccgcttc
    12301 gcccgcgagc acctcggggc actgcttcag gcctgtgacg gcacccgcac gctcgccgag
    12361 atcggcgagg ccacgggaat cggcccgcag ggcgccttcg aagccgtctg cctgctgtgg
    12421 accggcggca tcctcgagga gggcggaacc gagccgctgc ccgatccgca gccggccccc
    12481 gaactggcct gtctgctctc gcgtctgggg gattccacgg gcgtcaacga ctcctggcag
    12541 gacgccgccc gccgcctggc cgccgcccgt gtggcggtcc tgggcgacgc cggccttgcc
    12601 gaggagctcg cccgggcgct ggaacccacg ctgaccgccc gttccgacgt cgcgcccgag
    12661 cctgacgaca ccctcgccgt cgtcgtcgag acggacgcgg ccccgacggc cgacgccgcc
    12721 cgacgctgct ggacgctcgg catccccctc ctgcgggtgc gcgccgagca ggatgcggtc
    12781 acagtcggcc cctacgtgga ccccgggttc tcgccctgcc tggagtgcgc cacggccggc
    12841 gaacccgccc tcgagccgcc gccaggcccg catcgcaggg gctttgttgc gggcctggcg
    12901 gcccgggcgg tggccgcgct cgtctcccgc gcgaccatca cccacctgcc gggcgacgct
    12961 cggcgcaccg acctgaacac cttcacctac accgaccgtc cggtggtcac ccgcccgggc
    13021 tgcccggtct gctcggtggc gggcgggtcg tcggcgccga tcgccccctc ggcgcccgtc
    13081 ggcgcccgct acgagcagtc cgtggccatc cccccggcgg ccttcgtgga ctccaagggt
    13141 caccagcagc actacaagcc ctcgaatctg cgcctccagc gcgagttccg cgactggccc
    13201 gcctgcccgc gcacacccct tccggccgcc gacctgaagc gcttggaacg gccctggtcc
    13261 tcgaccgggc gggacgcatc ggctcgacga gtgtcggacg ccgcggcctc cgacaccccg
    13321 gcggaccgcg gaccgacacg atcggtcgtc cggccagccg gcccgacgct cgttgaactc
    13381 gccaccgtgc tggccctggc cgtcggcgtg cgcgagccga cgccgccgca agcgcgcacc
    13441 tccgcggact ctcccaccag cacctcgaag atgcgccgat ggacggccgc cggaggaaat
    13501 atcggctccg tcaccgccta cgtcctcgcc cccgcccgct ccgaggcgga cggcgggtcc
    13561 ggggccgggc gagcggaccg cgcctctgac agggccgacg ggccgatagg cggggccgcc
    13621 gacgaatccg gtcccctgac ccccggcgtg cacgcctaca tcgagagcga ccacactctg
    13681 gccctcatcg gacctcccgc cgagatcccc gacgacgcgg gggtgcggct cgtactgacc
    13741 gggaacgtgg acaaagtcgc caggaagtac ctctccttcg ccctgaggat cgccatccag
    13801 gactgcggct gctccctgga ggtcgtccga ctcgtcgccc gctgcctgga cctgcccctg
    13861 cgcacccgcg cccgctggga cgaacgggag ctggccgccg ccatcggcac cgatccgacg
    13921 cgcgaacccg tcttcgccgt tatcgacctg ggagggaacc gtgcgctctg actacgagac
    13981 catgcgcgag atcatcaacg gattctccga ccccgacggc cgccccacct ccgacggcct
    14041 ggccgcgtgg cgggcccggc gacccttgaa actcgccgtt ccccacatgc tcgaccccca
    14101 ggccgacgag ccctacccct acgacctgcg caccaccttc gcgcgccgct cgtcgaccac
    14161 cgactacgcg cccgaacccc tggacgccga gccgctcctg gccagcgtgc aggccgccct
    14221 ggtcgaggac gccggggcct gggaggacga cgccaccccg ccggaccccc cggacccccc
    14281 ggacgggacc gccgcggcgg aggcggccgg cgcaaccgcc gtccacctcg agcccttcgt
    14341 cgtacttctg cgatcccgcg gcgccccacc gggcgtctac aggatccgga ccaacgggac
    14401 cgacctcgtc gcgaacccgc ccgaccccga gcagatcgag gggatgaccg tgcagaagga
    14461 attcgcccgt gccggcgcca tcgtctccgt ggccgccaac ctcgacgagg ccgacgcctg
    14521 ggccggcgcc cacggctacc gccacgccat ggcccgggcc gccgccgtca tctactcggt
    14581 gcacctgcgg tccgccgccc gcggtctgac cggcacagtc ttcgcgggcc tgtcaccgtc
    14641 ggccgtgcgt cacctgctcg actccgacgg ggtcggccgc caccagatgt tcgcggccac
    14701 cgtagcggtc ccgcccagcg tggtcccgcc gtcctgaatc ggacgcggac cccgcccccc
    14761 agacgccccg cttcgcgggg tgaggggccc ggccccggca gccgagcccc tcgacaggac
    14821 ccgcaagggt cccgctcctg accagtgacg taccagagag gaggtgaaca tcatatgacc
    14881 accacgatcg acctcacgct gaccgacagc gacttcggca tcgaggagct ccccgagggc
    14941 aacgccctgg gctgcgcctt ctgcggcgcc tgcgcttcct gcccgtcctg cgcggcctcg
    15001 gcctcgtgcc cgtcctgcgc ggccagcgca tccacgacgt cctgctgaga cgtcatggcg
    15061 gcgggcggag aggtactgcc tctccgcccg ccgcccaccc ggacaccacg caccgacccg
    15121 agggggccct gacccgatga ccacgacgag ccagatcccg cgcctgcgtc gcggagtgaa
    15181 gctgatcgtc gggatggacg accagccgat gctcttcgac accgatgccg gcacctacca
    15241 ccggctcggg gccgccgccg ccgtcatcat caaccagttc gacggagcgc gctcactgcc
    15301 cgccatcctc gaccagctgc cccagaacat cgacgccgcc ggtaggcagc gcatcacccg
    15361 cctcgtggac tacctgcgct ccaagagcct gctggagggc ggcccgccgc tcaggacccg
    15421 accgtccgaa cgcgcccgca aacgcgtcga cggccggcac gtcgcacccc cgcacgtcgg
    15481 acggcacgag cagatccagc cgccccgctg gagcggaggc tggatgctgc cccgattcat
    15541 gctcatccgc acctaccggc gagccgtcgc acccgtggcg gcggccctcc accacctgcc
    15601 ggtgcgcacg ctcagcggac tcttcctcct tgcggcggcg ggaggctacg cggccggtgc
    15661 ggcgagcctg atcaacctgt ccgggggccc ccgcccaccg gcgcgcgtat tcttcatcgc
    15721 cgtcgccatc cagctggtga gcatcgtcgg gcacgaatcc tggcacgcga tcgtcgccgg
    15781 ctacctcggc acgcccgtgc gcggactggg cgtggccttc atgttctggg tgctgccgat
    15841 cgcttacgtc gaccgcaccg actcctaccg ggcgcgctcg cggctcgggc gcgccatgct
    15901 cgccatcgcg ggcgtgtgct ccgacggcgt cgtgtgcggg gcggaggccg ccgtcgcagt
    15961 cgcctcctcg ggcacagtgc ggcaggtagc cctgaccctg tgcgccttcc agctgaccat
    16021 gctcatcacc aacctcaacc ccctgaccca gtccgacggc gtggcgaccg tcgaggctct
    16081 gaccggctcg gtcaacctgc gcggtcgctc caccctcatc ctgcgctgcg ccgtcacccg
    16141 caccccgctg cccccggccc tggcccgaat gcggcccacc gtgcgcgcgg cctacgccgt
    16201 ctacggcctg ctgtgcgtcc tgcttggtgt ggtcggcacc gtagtgagcg tcacgtgggt
    16261 gctcttcatc gtgatcggca tcgtgaaagg tctgctcgca tgacgtcctc cggccccgca
    16321 gccccgcccg ccccggcatc cgcggcgtcg gcgccgcccg ccccggcatc cgcggcgtcg
    16381 gcgnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncatccgc
    16441 ggcgtcggcg ccgcccgccc cggcatccgc ggcgtcggcg ccgcccgccc cggcatccgg
    16501 ccgtccggcc ctgatgctgc ccaccctcgt gcgcctgggc gggctccccg cctgcgccgt
    16561 cccgcgtccg cagaacgccc tgatcgcggc cctggaggag gtgcgccgcc tcgaccggga
    16621 gacggagcgg gccgccgggc gactcctcga ccccctgtac gagctcatcc cgctgctgga
    16681 tcgcgacgag cgacgagcgg tcctgcacgc caaaaggaag gtgttccagt cacgcgccag
    16741 cggcctgtcg gcgcgggtgc gggccggcct gccctccgac atcggcgcca tgctcatcga
    16801 ctgggaccgc ctgatggccc aacgtcgtaa cgcgcgcacc cgcctggaca aggcggtggc
    16861 cgccgacctg gagaacagcc gcgccctact ggcccacagc ctcgacgacc ccgactacct
    16921 gcgctccgtg gccatagccg cccccgccct ggtgtcgacg ctggccaggc gcggacgcag
    16981 actcgacgat ccgcgtgtcc tgcgcacgct ctactcgctc gcgagtcgca ccgccctgaa
    17041 aaccagcccc ttctccggat tgaccaccgt cagcgaggcg ggccggccgg cccgcggacg
    17101 tcgccgctgc actgtggcgc tccacctggc ccacggcatc ctcatggccg tggcccgcga
    17161 cctcgacccc gccggccatc tgcgcctgga ggccgcgacc gtccgcgacg acgtcgtccc
    17221 ggccgggacc gacaaggggg aggcggcggg ccttgcgacc gacccggtcg gagcggccga
    17281 cgccgcccga ccggccacgg gcccggcgct gaccgtcgtc gccgaacacg actacgccaa
    17341 cggcatgatc ttccgacgcg aggagatcca acccgctcgg tggctcgccg ccgcccacga
    17401 ccgcctgacc ggcgggctca ccgacgcccc gccggtgagc gtgcgcgagg ccgtccgact
    17461 cgtcggcggc cgggacccgc gattgcgcct gcgccgtctg ctcgcctccg gcgccgtgcg
    17521 cccgcatccc ccgtgggcgc gcggcgagga ccccttcccc gccctggccg ccacactttc
    17581 cgagagccag cggggcgcgt gggccgagga cctcggccga ctggtcgagc tcgggcgggc
    17641 cgtcaccgtt gaggacggga ccgatcgggc cgagaggctc gccgacgccg ggcgcctggc
    17701 gcagcgggtc ttccccgacc acgaactggg ggccaggccg gcaggcctgc tctacgagga
    17761 ctgcgagtcc cgaggggagc gcaccgaccc gatggagcag gtgaccttcc gccgggacgt
    17821 cgagaccctg gccgggctcg tcgacccgtg ggtgacccgc tcccgcatct acgacctcat
    17881 ggtggagcgg tacgtcgccc ggtacgggcg cggcggggtg tgcgaggacc cgctcgcctt
    17941 cttcatgagt ctggcgcacg cccccgacgg cgatgcgcag atgctgcgcg ccgcagggca
    18001 ggacctcgcc tccggacccg accccgagcg cgccgccatg cccggtgggg tgtcggcctc
    18061 gccgcggcac atgggcgcct acctccagcc ggtcgtcgtc ggccggaggg cctcggccga
    18121 cgacaaccgg accgacgaac ccgctggtgc gggcagcggc ggacgtctga cagtggtcaa
    18181 cgccttcacc aacggcaacg gtgccctcca ggcccgcttc catcggctgc tcggcaggca
    18241 gtaccgccag cgcctggcac gagggatccg cgccgcctgg ggcatcgacc gggtactgga
    18301 gatccaagtc tccacggact gcaacaccgc ccaggccgtc tcctgcggcg tcctgcctcc
    18361 gctcggcctg cccggcgagc ccgagtccgc gcaggccgtt cccctgagct cgctgcggct
    18421 cgcccatgac ccgcgcaccg acactctgtt cctggccgac gcccggggac cggtcgggct
    18481 ggcctacctc ggactcatct cgcagcaccg cctcggggga tatctcgcct ggctggttct
    18541 tctgagcgac ccgtgggccc ggttggcgcc catggcggac cactggacca gccgacgtcg
    18601 gcggatggac ccgctgccgg acgaaccggt tcattccccg cggaccgttc acgggcgcct
    18661 ggtcactcgg cggcagtcat ggatcttccc ggccggccac gtggccgggc tcctggaccg
    18721 ggattcggcg gcgaccctcg tgcgagtcgc gagcctgcgc gaacgctggg ggatccccgc
    18781 cgaggtttac gtccaccagc atcgaggacc ggacgcggtc tcccgcgccg ccaccttcga
    18841 tgagcacaag ccgcgctacg tcgacttgcg ctctccggcc tccctgctgg cgctgcacgg
    18901 ctggatcgac cccgccgccg agcatctcag tctcatcgag gcgctgccgg cccgcgacca
    18961 gcaagcgggg gtcacacctt ccggtcggac gacggcgctg gagtacctcg tcggcctgca
    19021 gtggcccaag aacgacggag acgtgcgatg agagcgctcg acgacggcgt cgacgggatt
    19081 cgcgacacgg acgggatggc cgtgtcctcc gggccggacg ggacggccgc ggtcggacgg
    19141 ggccagcaga tcgactggct gtacgcgcgc atctactgcg ccggcggaga cgacacggat
    19201 gcgctgatgc ctcgcctcgc gcactggctc gacgcggtcc gtgcccactg gcccatccgc
    19261 tcggcccact tcctgcgatt cgtcgacctg cgcggtcacc acctgcgttt gcgggtccag
    19321 gccgctcccg acaccctgga tgaggtattc gcacgcctcg acatcctgga cgccgcggcc
    19381 cgtcgcgccc ccgtgcgcgc gctcgagcgc ctcgtctccg atccgctgac ctccggcggc
    19441 gggagcgggc gccccggcgt tgcatgcgcc gtgtacgggc ccgagtacgc caagtacggc
    19501 ggtccgaagg gggccgaggg ggccgagagc cacttcgaca tctccagccg ctggtgcttg
    19561 gacaaccggg tgtggaaggt cccgcgacct gtggggaggg tcggcctggt cgcccgcctg
    19621 ctggcgaacg cggccgttgc cgggccgctg cccgcggacg agctgctggc ggcccacctg
    19681 cgcatgtggg ggtaccgcct gcccgagcgt ctgcgcgacg gggccgcgct gggggccgtg
    19741 gtgcggcagg tcctcgagtt ccccctgaac ggaacgcccg gctgggagca cgccgacgaa
    19801 ctgacttcgc aggtggccga cgacgccgcc cgcaccgtag gccggatcgg tgcgggcgca
    19861 ggtgggcgcc gggcgctcga cctgctgcac atcgatgcca accgcctcgg cgtcaacccg
    19921 gccgaggagt gcgtcgccgg cgtgtgcgcc cggtacctgc tcggcggact cggcgtcgcc
    19981 ggtgcctcgg cgcggggatg agcgtccgga gcgctcagag gctgagacag gctgagactc
    20041 tcgacgccgt cggaggaccg ggcggctccg ccgccttcat ggccctccat cgctctcgct
    20101 cgtgtcggtc agttcgcttc gtatcaaaga ttattagtgc cgggttcgtt ggtgagcgga
    20161 ggttcaagga ggagagggtt gggcagggcc gagtggtgga tggcgttcaa ggcgtagagg
    20221 gctccggcgg tgccgagcat gaggccgcgc acgcttatga ccccgtaggt cagtcctggt
    20281 cgaagaccgt cggtttggat tcgccgaacc agattgtttt ggtaggaggc gagcagcttg
    20341 tggttcttca tctgggcgac gaccggggct aggatactcg ccttcttgat aaggaggttg
    20401 ggctggtccg tggcctgagt gtcattgtgg ctcatacttg agtatgacga ctgtcgtatg
    20461 aattctgggt ggatgtcgtc gggggagggg cgccgaggct agactgcgag catggtgagt
    20521 gtgtcgcgtg ctcgatggca ggtggacgcg gcgtctgccg tcgccgctgt ccttgtgtgc
    20581 ctgggactgg gcgtgtcggg gcagccggac tggctttggt cggcggtgat ggcggcggtg
    20641 ctggtgctcc gtcgcacgtt gccgtgggtg ttcgcgagcg ctgtcgcggc gatctcctgt
    20701 gcgcatctgc tggttgacag caggttgttg ttccccggtg acctgcttgt tctggttgcg
    20761 gtgtacacgg tggcgtcgta cgcgtcggta cgggcccgtc gggtcggtct tgtgacgggc
    20821 gtcgtctacg taggcgtcct gctttttagg gtcgtgctcg gcgagggcgt gcgcagctcg
    20881 cctcgaggct tctctcccgt catcgttatt gtcgcctgca tgattgcttc ctggtccgtg
    20941 ggattagtgg aacgtcagcg tcgggaggcc ctggctgagg ccgagcgacg tcgggttctc
    21001 gccgagcacg acgccgaggc ccggatccgt ctggccgctt acgaggagca tgagcgtatg
    21061 agcaatgaca tccacgatgt gctcgcgcat accctgaccg ggatcatcgt gcaggcggag
    21121 agcgggcggg ctatctccgt cgacggcgag ccgcgtgagt tgttcacacg catctcgcag
    21181 accggacgaa ccgcccttga tgaggtccgg gggcttctgg cctcctacga ggagagtccc
    21241 ggcacgcagc cctcgccggg tcttgaggac ctgggtagtc tgctcgcaac cttcgagcag
    21301 gccgggctca atgttcggcg agtcgacagt ggggagcgtg tggacctgcc gcaggggatg
    21361 gctctggcga tctaccgagt cgtccaagag tccatgacta atgctctgcg tcatggcagc
    21421 acccgacagg ccaagctgac gctggagtgg acatcgcaag agctgacggt gacggttgtc
    21481 aacccgctca aggacgacgt cgatctggcg gctgtcgagc actgtcgagg actcagcggc
    21541 atccggcgtc gctgtgccct gtacggtgcg caagcacaga ttcgcgctgg ggaggagttc
    21601 accgtcaaga ccgtgtggcc gctcgctcct gggccggcgg ggaaggtgtc gtgagctcaa
    21661 cgagtcaggt gatcaccgtc ctgatcgtcg acgaccaagg gctggtgcgt gacggtttca
    21721 cgcgtatcgt cgacgcgcaa ccggcgatgc gtgttgtggg cgtcgcctcc aacgggcgtg
    21781 aggctatcgc tctggcgcgc gccagacgac ctgacgtcat cttgatggat gtcaggatgc
    21841 cgggcgtcga cgggatagag gcgacgcgca cgattgttca ggaggacgag agcattcgag
    21901 tcctggggct gacgatcttc gataatgacg cctatgccgt gcggatgctc aaggcgggtg
    21961 cgaccggttt cgttctcaag gacagcaccg ccgaccagct ggtcgacgcg atccggtcgg
    22021 ctcaccatgg cacgctgacg gtggctcctg ctaccggtcg gcgtctcctg cgcaggctcg
    22081 tggagcacga agcgccccgg cgcggagcgc cggccttgcg ggagctcact gaccgtgaag
    22141 ccacagtgtt tcgtctcgtg acgtcgggga tgtcgaatct ggagatagcg cagcacctgt
    22201 gtatttcgga ggtgacggtc aaatctcacg ttggacgtgt tctgtccaag cttggagctc
    22261 gggaccgtgt ccagctggtc ctgtgggcgc accgcaacgg ggtgctgccc gtctcgtccg
    22321 agtcggcggg cggtccggag ggtccggggg gcggggacgc gtccgatcgc ggtgcctgac
    22381 tgtgacgtga cgggccggac ccggtcctac cttcggtgca gactcctgcg caggtatcgg
    22441 tcaggaatcg tctccgggca cgattcacgc cgtccgagtc ggcgggcatg atgaggacca
    22501 tgccacgcgg aacgaggatc tgacatgagt gccgccatca ctacgtcgaa cctgacgaag
    22561 cgcttcaaga cgcatgtcgc cgtcgactcg ctgaacttgg acgtgccgca aggagcgatc
    22621 tacgggttcc tcggaccgaa cgggtccggg aaatcgacga cgatgaagat gctcctcggt
    22681 ctcacccggc ccactgaggg cgagatcaga gtcttcgaac aggacctcac gcccgcctct
    22741 cgtacacgaa tgcttccgtc catcggatcg atgatcgagg cccctcccgg ttatgggcac
    22801 ctcaccgggc tggagaacat gaggatcgtg caggacatgc ttgatctctc cgccgttcag
    22861 atcgagcacg ccctggagac ggttcggctg accgagcaca agaacaagct tgtgcgcaac
    22921 tactcactgg gtatgaagca gcgcctcggg atcgctatgg ctctggcgcg cgaccctgcc
    22981 ctgctgatcc tcgacgagcc gacgaacggt ctggatccgg ctgggatcga ggagatccgt
    23041 accctgctga tcaggcttgc cgggcacgga atcaccgtca tggtctccag ccacctgctc
    23101 gacgagatcg acaagatggc gaatgtcctg ggaattctcg cgaacgggag gatgatcttt
    23161 caaggtactc gtgaccaact cttcgaacac tcgattcccg atcttgtcat tgagacgccc
    23221 gacgcccggg ccgccctcgc gcaggggatc acggcgaccc ccatcgcgga aggcatccgg
    23281 gtcagcggcc tcggcaagga ccagaccgct gagctcgtgt accgcctcgc ggtcgcgggt
    23341 gtcccgatcc acggtgtacg acgggtgcag cagagtctgg aggacgtgtt catggacctt
    23401 accgggcgcg gggggctgct gtgaaccggg cgatccgact cgagctccgc aagatgcgtc
    23461 gcctgcgtac cgggctgacc accacggccc tggtgctcgc cgtcgtcgcg ctgtcgagca
    23521 tctcactgtt ctccggcagc acgcgtcgaa cttttgacga tcccgaggct atgccttggg
    23581 cgacactgat gatgtcgtac gccttcatgg cggcgatgac ctcacccatt ctcaccgcgg
    23641 tcctggccag ccggcagacc gatatcgagc actcaggcgc cggctggcag ctcgccgcca
    23701 ccgccggcta cagccctggt gcactgtgcc gagccaagct cgccgcgctc agtctcgtcc
    23761 tgactcccgc ggtcatcggg cagacgtttc tcgtccttgc ggtcggggcg ctcgtcggca
    23821 tccacgtgcc gatcaacgcc ggcccctggg tcggctacac tctccttctg ctcctggtcg
    23881 acattgcctt cctggcgctg cacatctggc tggcctgcgt cggcgagaac cagctcatga
    23941 gtgtggggat cggaatgctc ggcgccttcc tcgctgtgtt cacgctgctc atgcccggtg
    24001 ccgtcgcgcg cttcataccc tggggttact acgcgatgat ctcctacgtc ggtcaacaag
    24061 gcgacaacat tatctacatt accccggact atgtctggat cgccggcttc ctccttctcg
    24121 tcggtgtcgt attcattcag atgacacgcc gtcttgaccg gactgaaagg tgagacttgt
    24181 gttccgcgca gaactcatta agctcaagcg atcctccatc tggctcatag ccctcgccct
    24241 tccgctcctg gcggtgatca ccgggaccat caacctggct aacaaccctg acgcactcaa
    24301 cgccggctgg gcttccttca cctctcaggt gacgcttttc tacagtctct tgttctactc
    24361 catgggtatc gctctgctta ccgccaccgc ctggcgcatg gagcaccgcg ggaccaactg
    24421 gaacctcctg ctcaccggta cccggcgccc ggcccggctc gtgctcgcaa aggtcgtcgt
    24481 tatcgcggtc cccgttgcgt tcatgcagct cgttctcgtt ggcggcaccg ttgcctccgg
    24541 cgtcgttgtc ctgcgccttg acggggccgt ctcgtggcag ttcgccgccg tcggtgcgct
    24601 ctccgtgatc gtggcgctgc ccctgatcgc gttccaatcc atgctgtcga tgctgctgaa
    24661 gtccttcgct gtccccgtgg cgatctgctt gttggggtgc gtcgccagca tagccgccgt
    24721 cacctcagat gctctccacc cactcagcta tgcattaccg caggcactta acactcgcac
    24781 cttgaacctc ggctccacgg cgttcgccgg ttccggcggc ctcactggtg ccgacgtcgc
    24841 cccactactg ggggcggcgc tggtcctcac tgccacagcc attggcctca caacggttgc
    24901 catgcgcgtc atcaaacttc gttagtggat gtcatggcgg aaccgagagt gcggttcttg
    24961 cgttaggact gtcgattcct gaggatcggg ggcgcggtcc tgcgcccgcg catgagaggc
    25021 tcgagtgttc tcggcgcctg ggaccctgcc gtgcagaatc gccttcccct gccattgcgg
    25081 aaagcccata aacccatgta cgccaacggc tgcacctatc cgcgatgatt ccttccgccg
    25141 tcccatcgga cggagaggga gtggatcgcg gccccgaaga tccgctcgtc ctatacgggt
    25201 cttggatgac aacatttgta ttgcctccgg cctcggatcc tgaagagcaa tgcctttacc
    25261 ttctcagccg ctttcactgc ccacccatca ggggcaggaa atgcagcacc gaatgatgag
    25321 gcaacagaat cgggggtatt cggggcggcg ttcgcgctct gagagacggc accgccgccg
    25381 cggcctgtgc cggccatcgc cggctgagga ccacccggcg gtacgcccgc aggccgtcag
    25441 ccacgtcctc aacggagccg tagacccgac gcacacccgt cccaccattc gagatgccgc
    25501 tgaggcgcgg gcggggtgtg cgccgatgcg gccggtgtca gtcgtccagg tgcccgacca
    25561 gtcgggcggc caggcccgtg taggtcgcgg gcgtgagggc cagcagccgg gcctcgacgt
    25621 cgtcgggcat ccccaggccg gagatgaagg cgcgcatggc ctcgggagtc acccgcttgc
    25681 cgcgggtgag cttcttgagc cgttcgtagg ggtcggccat gccggtcgcg ccggccaccg
    25741 acgccgcccg catcgcctgc tggacgggtt cgccgaggac ctcccacgtg gcgtcgagat
    25801 ccgcctccag ccgggcggcg tcgacgtcga gcccggccag accgcgccgg atgttgtcga
    25861 tcgccagcag cgagtgcccc agggcggtcc cgatgttgcg ctgggtggtg gagtcggtca
    25921 ggtcccgctg gaggcgcgag gtcaccagcg tggcggccag cgtctccagc agggagcagg
    25981 agatctccag gttcgcctcg ccgttctcga agcggatcgg gttgaccttg tgcggcatgg
    26041 tggaggagcc ggtcgagccc tgcgtggcga ggcgctggcg gaagtagccc agtgagatgt
    26101 agctccacac gtcggtggcc aggttatggg cgacgcggtt gaagcgggcg atgtcgcagt
    26161 agagctcggc ctgccagtcg tgggactcga tctgggtggt cagcgggttc cagaccagtc
    26221 ccagcccctc gacgaaggtg cgggagaccg actgccagtc ggcttccggt acggccacga
    26281 cgtgcgctcc gtacgtgccg gtggcgccgt tgaacttgcc cagatactcg gcgctctcga
    26341 cgcggcgcac ctggcgggtc aggcgccggg cgaggacggc gagctccttg ccgagcgtcg
    26401 tcggggtagc gggctggccg tgggtgcggg cgagcatggc ggcgccggcg tgctcgcggg
    26461 ccatggccgt caggtcggcg atcagaccgt gggcggccgg cagccaggcc tccttgacgg
    26521 cggagcgcac cgtcagagcg taggcgagat tgttgatgtc ctcgctcgtg cagaagatgt
    26581 ggacgatctc gtggacggtg ggcaggacgg tgggccctcc gtcggcaccc gacaccgacg
    26641 ggtcgtcgcc cgccgcgtcc agacgtcgct tgaggaggta ctccacggcc ttgacgtcgt
    26701 ggcgggtgac ggcttcgacc tcggccagct cggcgatctc ggccgcgccg aaggaatcga
    26761 cggtcccgcg caaataggcc ttctcggatt cggacaggcg cggggcgccg ggcaggacgt
    26821 ggtggtccgt caggtggatg agccactcga cctcgacggc caggcgggcc cgattgaggg
    26881 cggcctccga caggtggttg accagtggtg cggccacggc gcggtagcgg ccgtcgagag
    26941 ggcccagggc gatgacgggg gagacggtgg agaggtcgac catggggttc attatggggg
    27001 cggtgcggat cgcaggctcg ccggcgagcg cagcgctggg tgcgggaggt ggagccgcac
    27061 tggttcgaga ctgatgccgg gcagtgcccg cgcgatcgat gcgggcccgc cgaggtcggc
    27121 cgacgtgtcc aaatctgcca caaaggactt gttctgtacc atgctgcgca ccgcagatcg
    27181 ttgagataac gcggatcatc tacgctttcg aatgtacaaa aacggccttt gtgacagatt
    27241 tggacaatcg agaacaatcg ggagtccgcc gacggggtgg tgccccggtc cggggcaccg
    27301 ggcgcccgtg agtcgaacgg gccgccgagc cttccaccgc cctcgccccg ggctcgtctc
    27361 cgccgttccg gctcagaaca tcgggtccca gctcggcagc atgacgggct cgacctccag
    27421 cgccgcgcgg acctcgtccg gcaggcggct cgcccgtacg accacctggt agacgtactc
    27481 atcgaaccac gagtcgttca tcgtgtggaa gcccttctcg ccgagcttgt cgccccagga
    27541 gttctccaca cgccagcgcc gcggcgcatt gtcgaggagg tccacgcccg tcaggcacat
    27601 ggcgtgggtg agggcggatt cgcgcgccac cagccgctcc gccttagtca tggacagctc
    27661 gaccccgtac aggccctcgt agtcgtgcag ggccgcgtcc cagacgcccg acttcttctc
    27721 gcgctgcttg gcgacatcgc aggcgaacca caccggttca ccgtcctgga tggcggcgat
    27781 cgcggccgcc ttgagaacat ccagagcggc ggtgacgtgc tcctgggtgg gctcgcccac
    27841 catgagatcg gtgcgctcaa taccgaaccg ggtgttgacg gggatctcgg ggcgcgggtc
    27901 gtgggccacg acgacgaact cctccagccc ggccgcgtag cgctcggcga attcgcgcgg
    27961 ggtcagcgtc ccgacgcggt ggaagacctt gtccttgtcc cggtactgcc acatgaactc
    28021 ggtcggcggg gtgcccagat ggatggcgag gagccggtgg acgtcctcca tcgccgccga
    28081 gcggaccggc tcggggtccg ccccggcggc caccgccgcg cgcaggcgca gagccgcgcg
    28141 acgcaggacg gtggccaggt gggcgttcat ggcgtccgag tcggtcgccg agtgggtgtc
    28201 cggcatggcg gcgtggggga ccatcccgta cttgctcacc agtcgggcga actcgggcca
    28261 ccagccgccg tcgctgatcg gctcgcgcag ggtctcaacc acttcccggt cgctcagcgg
    28321 acgctcggcg tcgtcgacgg cgcggtgcag gaaggcagcg gccttctcca gcttgtcatg
    28381 gaagtagatg aagttctggc tcagctccag cgagtcgaca gtcagctctt cgatgaggga
    28441 ggcgcgcagg acgttgaggc cggcgaaggc gcagcagcgg cccgagcgct tctggtcggt
    28501 aacgatcgcg tcggggatga ggtctgagac cgaggtgtcg atcgaggcga tgacccggcg
    28561 gtccacggtg agtttctcga cgtctgtggt ggcgaccgcg ttgccggcga cacgtgcggc
    28621 gggatcggca ctgacggcgg cgttgcgagt gtccacccag gcggggtcga cggcgtggga
    28681 gcggggatcg atcatggcga gagggtagcg cggccgcggc gaaccgtccg aaccggccct
    28741 cttccccggt ttcccccggc ggcgggaccg cagtcgctaa cctcgacccg tgaacgagcg
    28801 acagatgcag tgggaggcgc gttacgccgc cgtcgacagg ctgtggtccg gggatcccaa
    28861 cgactggctg cccgagctcg ccctcggctg ggagccgggc cgcgccctcg acctgggctg
    28921 cggggagggc gccgacgccg tctggctcgc cgagcacggc tgggacgtca ccggcctcga
    28981 tctgtcggcc accgcgatcg cgcgcatgcg ggcccgggcg cgcgatcgcg gcctggcggg
    29041 gcgcgtccac ggcctggttc tcgatgccac ccgcgaacgt ctgcccgccg gccccttcga
    29101 tctcgtcgcc gccttctacg tccacggcgg ccccatgccc ggctcactcg acctggtcga
    29161 actgctgacc cggggtgcgg ttcttgcggc ccccgggggt cgggtgatga ccgccgtcca
    29221 ttgcgtcaac ccgccctggc accgccacca cgcccgcacc tacactcccg ctgaactgct
    29281 cgcgggcctg gcgggggcga cgaagggatg gcaagtcgag gtcgctcagg agcggtggcg
    29341 ggaggtcccc ggtcccgacg gcgaggcggg tcggcgctcc gacgccgtga tctgcctgcg
    29401 ccggccggtg tgaaccgggc accaagagcc cggcctccgt ccggggaggg acgccggcct
    29461 ttcgacactc gcgcgggcgg agcggcacgc gggcttccgc tcgcagggag acgcgagggc
    29521 aggatgggag catgaacgcc catgagtccg gcccgcccga cgatgcggcc tcgcccggcc
    29581 ggggggccga gcacgattcg cccggccggg ggcttcagcc cgaggcgggc ccgggggacg
    29641 agatcgccgg gcccggggcc gaccacgtgg atggcgtccg ttcggggaac ggggcggccc
    29701 tcggctccga tccggcatcc gaacccgacc cggttccggg gtggatcgcc gatctcgttc
    29761 cggtggccga cgacgcccgc gccatcctgc tcgccgaccg cgtggtcctg gccgcggggg
    29821 tgccgctcgc cctggtcctg ggctgggccg gggcgaggcg ggacgtcggt catcttccga
    29881 tatgggcggg tgcgctcatg gcggcggccg ccgcggcggt cgtcctnnnn nnnnnnnnnn
    29941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnngcgg ccgccgcggc ggtcgtcctg
    30001 c
//
