LOCUS       NZ_CP023202            22733 bp    DNA     linear   CON 21-MAR-2024
DEFINITION  Streptomyces xinghaiensis S187 chromosome, complete genome.
ACCESSION   NZ_CP023202
VERSION     NZ_CP023202.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces xinghaiensis S187
  ORGANISM  Streptomyces xinghaiensis S187
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7137891)
  AUTHORS   Zhao,X. and Yang,T.
  TITLE     Draft genome sequence of the marine sediment-derived actinomycete
            Streptomyces xinghaiensis NRRL B24674T
  JOURNAL   J Bacteriol 193 (19), 5543 (2011)
   PUBMED   21914869
REFERENCE   2  (bases 1 to 7137891)
  AUTHORS   Chen,L., Zhao,X. and Lin,S.
  TITLE     Genome mining of a marine derived strain Streptomyces xinghaiensis
            reveals biosynthetic ability of xiamycin analogues
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7137891)
  AUTHORS   Chen,L., Zhao,X. and Lin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-SEP-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
REFERENCE   4  (bases 1 to 7137891)
  AUTHORS   Zhao,X., Yang,T. and Chen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2011) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2, Dalian, Liaoning
            116024, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: Streptomyces xinghaiensis S187 genome
            sequencing
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000220705.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 05:53:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,157
            CDSs (total)                      :: 6,072
            Genes (coding)                    :: 5,922
            CDSs (with protein)               :: 5,922
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 36 of 150
            Pseudo Genes (incomplete)         :: 134 of 150
            Pseudo Genes (internal stop)      :: 6 of 150
            Pseudo Genes (multiple problems)  :: 26 of 150
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:47:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5400939
            Orig. end                         :: 5423672
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023202.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Shanghai Jiaotong
            University, School of Life Science and Biotechnology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22733
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="21"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22733
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22733
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12733](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12733
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(459..1160)
                     /locus_tag="SXIN_RS23055"
     CDS             complement(459..1160)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984216.1"
                     /locus_tag="SXIN_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_095757454.1"
                     /transl_table=11
                     /translation="MTRALALRALVACGTGAATAAALALTGAASATAAPADSTAAGPTT
                     VSPAGHQFAATLNGSATFKAGAVTVTCTVSSSAPVADGTSDANQVPDAPGNTNAEGPVE
                     SVINAPTYSSCRSSLPGVSVTITTTGVWGVSMQHGDPSSATLTIPQGGFVLKTSGLASC
                     TVTAAPDGAAPVAGTWTNGAPSQLDFTDAQVPVSATGGFGCPTSAETSAFNATYDVTDV
                     TDPASQITVTG"
     misc_feature    complement(1146..1148)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1270..1776)
                     /locus_tag="SXIN_RS23060"
     CDS             complement(1270..1776)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571938.1"
                     /locus_tag="SXIN_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_019709305.1"
                     /transl_table=11
                     /translation="MPGRAPSEPARPAASPGTPAAAGTEVTGGSPGTRPGVRARWRRWR
                     RSRPFWGGLLTVLAGLEISLIPLAPVEMMLHQGIAGLPSVLLALIVIVMGLSAWFAPHY
                     RGLAGVVTVLLAAAALVMSNLGGFFIGTVLGIVGGSMIFAWRPVPRQARGDTAGERPPP
                     RRRRR"
     gene            complement(1778..2413)
                     /locus_tag="SXIN_RS23065"
     CDS             complement(1778..2413)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571937.1"
                     /locus_tag="SXIN_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6230 family protein"
                     /protein_id="WP_019709306.1"
                     /transl_table=11
                     /translation="MEDVRSRDDADGYETGRVGLRRFALLAVPGFAATAALAVALANGA
                     LAASFAVSGQEFKVSADELTGDGFVQYGSFDTNVRDELLPVAVTGLRKAEMTNLCQSVV
                     TSLPVVGDISLKLSAGTGKKKVEATDLMLDATQLAGNASFNNIEIGRDASTLDKGPDGA
                     QGMQDLFSQQADDIRMTNLKQTAWATTAGTFKLAGLHMKIHKGRTECF"
     misc_feature    complement(2339..2341)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2701..3546)
                     /locus_tag="SXIN_RS23070"
     CDS             complement(2701..3546)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180135.1"
                     /locus_tag="SXIN_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ECF transporter S component"
                     /protein_id="WP_095757455.1"
                     /transl_table=11
                     /translation="MTPQLPPARERPAAGRVRAVRLGPRSVAALVLVSAIGVMAFGWPL
                     LADSASGLAHSGDAPWLFAALLPLLVAVVVATVADTGLDAKAIAMLGVLAAAGAALRPL
                     GAGTAGLEPMFFLMVLSGRVLGPGFGFVLGAVTMFASALLTGGVGPWMPFQMLSMGWVA
                     MGAGLLPGAEGLRGRAERWLLAAYGGAAAVLYGTVMNLQGWPYIGGLGTGISFVPGDPV
                     HENLVRFAAYCLATSLGWDLPRAALTVVLTLTLGSTVLAALRRATRRAAFEAPVAFERP
                     "
     gene            complement(3543..5270)
                     /locus_tag="SXIN_RS23075"
     CDS             complement(3543..5270)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987249.1"
                     /locus_tag="SXIN_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_095757456.1"
                     /transl_table=11
                     /translation="MIRFDDVSVHYEGAAAGPALTGVDLTVPEGELCLLVGPSGVGKST
                     LLGTVSGLVPHFTGGTLRGRVTVAGRDTRTHRPRELADVVGTVGQDPLAHFVTDTVEDE
                     LAYGMESLGLAPAVMRRRVEETLDLLGLAALRDRPIATLSGGQQQRVAIGSVLTPHPRV
                     LVLDEPTSALDPAAAEEVLAVLQRLVHDLGTTVLMAEHRLERVVHYADQVILLPAPGAA
                     PVTGGPAEIMAVSPVTPPVVALGRLAGWSPLPLSVRDARRTAGPLRERLAGLAPDPYPV
                     RAPHPAATGATAGTAGTAPDTTPAAELSRLSVRRGRTEVLRRIGLTVRPGETVALMGRN
                     GAGKSTLLNTLAGLHRPAGGTALAGGAVPHRTPPRDLIRRVGLVPQEPRDLLYADTVAA
                     ECAAADGDADAEPGSCRALVTALLPDVSDTTHPRDLSEGQRLALALAVVLTARPPLLLL
                     DEPTRGLDYAAKSRLVEILRGLAAEGHAVLLATHDVELVAELAHRVVILADGEVVADGP
                     TAEVVTASPAFSPQVSKILAPQPWLTVSQVRDALAAPDSPDSPDSPDDPGTPRTEAAR"
     misc_feature    5257..5270
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            complement(<5762..7057)
                     /locus_tag="SXIN_RS23080"
                     /pseudo=""
     CDS             complement(<5762..7057)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556843.1"
                     /locus_tag="SXIN_RS23080"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSPGAPGTPRPGPLDSARPAAGRGAVPPRPATAAVPRSRRPERGT
                     DGAARLPGAEGTGAAPSAVARLRGRLASRAPEASRGNALHAGAWWLWALGLATAASRTT
                     NPLLLALLATVAGYVVAARRTDAPWARSYSAFLKLGLVVIAIRLVFSVFLGSPIPGSQV
                     LFTLPEVPLPEWARGVRIGGRVTAEGLAFAFYDGLKLAVLLACVGAANALANPARLLKS
                     LPGALYEAGVAVVVAMTFAPNLVADVVRLRAARRLRGRADRGVGAILQIALPVLEGALE
                     RSVALAAAMDARGYGRTARVPAAVRHTTTVLTLGGLLGVCAGTYGLLAAEGAGFGLPVL
                     LLGLSAALAGLWLGGRRSVRSRYRPDRWGPRSWLVAGSGAAVAAVMIWSASAGRADLHP
                     SVVPLTAPALPLWPAAGVLLGLLPAVAAPAPAS"
     gene            complement(7054..7740)
                     /locus_tag="SXIN_RS23085"
     CDS             complement(7054..7740)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518433.1"
                     /locus_tag="SXIN_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SCO2322 family protein"
                     /protein_id="WP_337589360.1"
                     /transl_table=11
                     /translation="MLLLVAAVTALGAGPAQAEGYRYWSFWQRDGGSWSYATEGPATAR
                     PADGDVEGFRFSVSVNTQDAAKPRGTAGFDAVCADTPAEDGRKRVALVLDFGTAEDAPD
                     GERPPEPRTECASVPEDATSGEALAAVAKPLRYNTSALLCAIAGYPERGCGEQVSGEAG
                     AGDGGADPAGGSGPGGSGDDRAGDDRAGEPAGGDGGGSSTGLYAGAAAVAVLAAGAAWQ
                     ARRRRG"
     gene            complement(8040..9317)
                     /locus_tag="SXIN_RS23090"
     CDS             complement(8040..9317)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989881.1"
                     /locus_tag="SXIN_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_095757457.1"
                     /transl_table=11
                     /translation="MNVRRTAAALAASAVLGALAAPAASAGTAAPSSSPAPKPPSGLHG
                     TKDPAYDGVWRQSIALLAQDTAGVTPAAEAVDWLTGQQCSSGAFAAYRADAGAECDAKT
                     PVDSNATAVAVQALAALGGHTGEVRKAVGWLKSVQNEDGGWGYLPGTPSDTNSTSVVVG
                     ALAAAGEKPGAARAGGKSPYDALAELQLGCDADAGDRGAYAFQPDKKGRLLANADATVA
                     GVLAGHGEGLAVTPATGDGGEDGGAPEPLECGSGADAGRTPEEAASGAAAYLTGLLEKD
                     GHLTSLAPGADEPVPDHSNTAEAVIALVAAGRPEAAEAPLAWLEKNSAEWAADNPAGLG
                     TLVLAAHAAGGDPRSFGGTDLVKELNATGPEPESVPAAGADASEEGEKSGSGDVSVLWW
                     ILGAGVLAGLVAGAVLMLTAGRRKRS"
     regulatory      complement(9483..9644)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    9644..9659
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            10001..12733
                     /gene="lanKC"
                     /locus_tag="SXIN_RS23095"
     CDS             10001..12733
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827685.1"
                     /locus_tag="SXIN_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_095757458.1"
                     /sec_met_domain="micKC (E-value: 4.1e-243, bitscore: 807.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.1e-12, bitscore: 44.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLGYAVYCDADRTFYDAPHRLSAGTEDTPGAPGALYEHARREAL
                     EGWQRHSNGDWLAFRPLDTSLPAQGWKIHVSATLDNAEKILTQVWDYCVPRSVAFKFIP
                     GRHLLRTRNAKYADRGGSGKFITVYPENDEQFGTIARELGELLDGEPGPYILSDLRWGA
                     GPVHVRYGSFTERHCYDEQGVLRPAVENAEGKLVPDRRDPAFHIPGWVEPPACLAPHIE
                     ARTATRTTGIPYRIEKALHFSNGGGVYAGTDTRTGEKVVLKEARPHAGLAADGADAVSR
                     LERERAALERLSGLPYTPEVRDSFVLGDHHFMVMEFLEGKPLNTFFARRHPLIEADPAP
                     EALAGYTDWAIRMHGLVTEAVEAVHARGVVFNDLHLFNIMVSEDESSVALLDFEAAAHI
                     DEGRRQVVANPGFVAPAGHRGFDVDRYALACLRIALFLPLTSLFAIDRGKAAHLAEIAA
                     REFPVARGFLDEAVAEILRDPAAQPPAAGADETAGSAPAARAPYLPVDPADWPHSRDSM
                     VRAILASATPDRHDRYFPGDIAQFRAGGGLCYGYGAAGVLHALAETGGGRHPEAEEWLL
                     RRTERPAPGTPLGFYDGLAGIAWTLDRLGHRERALELAGLTLAEDWSGMAPDLHSGLAG
                     IALALDSLGASTGEIALEDAAARCTRIVADRFARSDGTEGATGGGTGRTGGGVPRAGLL
                     HGAAGQALLFLRRYERTGDPVLLDLAAEALRRDLARCVKGPDGALQVDEGKRTMPYLGA
                     GSAGIGMVLDDYLAHRHDEDFDRARRDIVRAAQGKFYAQPGLFRGAAGMVLHLARTTTG
                     GPGTDETALRRQITALTWGAVPFRGELAFPGEQMMRLSMDLSTGTAGCLLALGSALHGS
                     PVHLPFLPPPAGRPHEPVSAGGRTQENPVPTDIKERTVS"
     gene            12730..12864
                     /locus_tag="SXIN_RS23100"
     CDS             12730..12864
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="SXIN_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_019706186.1"
                     /transl_table=11
                     /translation="MTLLDLQTMETPAEEITGELATGGGSRASLLLCGDSSLSVTTCN"
     CDS_motif       12730..12795
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQTMETPAEEITGELAT"
                     /locus_tag="SXIN_RS23100_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12796..12864
                     /prepeptide="core"
                     /locus_tag="SXIN_RS23100_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="26.80"
                     /molecular_weight="1972.2"
                     /monoisotopic_mass="1971.0"
                     /core_sequence="GGGSRASLLLCGDSSLSVTTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQTMETPAEEITGELAT"
                     /leader_location="[12729:12795](+)"
                     /alternative_weights="1990.2"
                     /alternative_weights="2008.2"
                     /alternative_weights="2026.2"
                     /alternative_weights="2044.3"
                     /alternative_weights="2062.3"
     gene            12993..15107
                     /locus_tag="SXIN_RS23105"
     CDS             12993..15107
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359196.1"
                     /locus_tag="SXIN_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_095757459.1"
                     /transl_table=11
                     /translation="MATEPAGTGPSAEARNTGDRSPGAPAVTPGEEPRGAEPRGAEPRG
                     AEPRGAEARERARTGKAPNGKTRNGKTRTGKAPNGRARTAGARRHDEARTPPAAAGASP
                     ADPAPGARRLLAGAARRSTGRAVLILLATTASAAATIALPAVLGHTLDLLLAGRDGAQP
                     WVALCGVLLAAEVLLDALTAHATGVTNARSTAWLRNRGTAHLLSVGPRRAARFTPGDVV
                     TRLTGNAAEAGTVPATAAASAASLLTPVGGIVALVLVDVWTAAVFLAGVPVLLLLLRVF
                     VRSSSDSVTRYQRIQGDIAARLMEALGGARTVAAAGTARRERDRVLAPLPELDAQGRRM
                     WQVYGRAVTQGGILVPLLTTAVLAVGGVRLAAGQLSVGELLAASRYAGLAAGIGAVVSQ
                     LSALVRGRAAARRTAELLSAPRVRHGTRRLPPGGPGRLELRGVTVVRGGARVLDGVDLT
                     VPGGVTAAVVGRSGAGKSVLAAVAGRLEDPDGGTVLLDGVPLPDLDRAELRREVGYAFE
                     RPALFGGTVGGAIAFGAGEPPEETVRSAARTARADSFIRLLPAGYATRLADAPLSGGEL
                     QRLGLARAFAHAGRLLVLDDATSSLDSVTELEVGRALTRDVRAGTRLLIAHRVSSAARA
                     DLVVWLENGRVRAVGPHEVLWERPAYRAVFAGTGSGTGTDAEAPDPPGPAVTGAPGPVP
                     GGRGRTGGAP"
     gene            15131..17023
                     /locus_tag="SXIN_RS23110"
     CDS             15131..17023
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827682.1"
                     /locus_tag="SXIN_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_238153838.1"
                     /transl_table=11
                     /translation="MRPRPRSGKDRAGRGALRRILPQARRFLGARLRVLAALGGWSLLE
                     SAHTFLGGYSVAQALDRGFLAGDTRTGLLWLAVAAAAVVVGGFANQGVFRGLAGLVEPL
                     RDGLLRRVVSASLREAVADPARADSAVVSRITHQTETARDSFAGLVLVARSFLFTAAGA
                     LLGLASLAPLLLLVVGPPLLLGLALFLATLIPMAARQRDYLRADEALAEEYGAVAGGVR
                     DIVACGAEDRTAARAARLADAELGAARSLARWAAARTLSLGVAGQLPVLLLVFATPWLL
                     DRGVTAGELLGALTYLTQSLLPALHTLMTALGAAGTRLLVILDRLTGGHDGPPGAETPG
                     PGAPGSVKGRAAVPHPDAAFSAAPPVPIAVPIAVPIAVPIAGPDGGPEPGAPAVELRSV
                     TFAYGAGAHPVLRDLDLTVGAGECLAVVGPSGIGKSTLTGLVAGLLTPGRGEVRVLGRP
                     ARAWPAGEPARLRVLIPQQAYVFTGTLRENLLYLCPDGAPPEAVSASAEAVGLTGLADR
                     LGGLDAVVDPAVLSQGERQLIALARAHLSPAPVVLLDEATCHLDPVAEERAERAFAERP
                     GTVITVAHRISSARRADRVLVMDGVHAVCGSHDELLDRSGLYRDLVGHWQTVRV"
     gene            complement(17113..17742)
                     /locus_tag="SXIN_RS23115"
     CDS             complement(17113..17742)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="SXIN_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_019709308.1"
                     /transl_table=11
                     /translation="MIRVLLVHDIGLLRSALAALLGREHDLEVTAATWDKFPARAQATR
                     PDVCVVDADNPASDSLTAVLEAAEPEGRGAQGLRSGRRSALLALVTAGRPGALRRAFDA
                     SALGYVSKNATPQRLLDAIRKVSKGERFVDESLAFGFMQAAEMPLTARELSVLSLAAEG
                     APIAEIAKSLHLCNGTVRNYMASVIRKTGARNRIDAVRISQSAGWV"
     misc_feature    complement(17386..17388)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17919..18635)
                     /locus_tag="SXIN_RS23120"
     CDS             complement(17919..18635)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008743687.1"
                     /locus_tag="SXIN_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_095757460.1"
                     /transl_table=11
                     /translation="MATESASQLSPSRLTERQEARRRSILRASAELASRGGFDAVQMRE
                     VAESSGVALGTLYRYFPSKIHLLVATLRDQLQRLYETPARRPVAAEAPSARVAETVLRA
                     FRAMRREPLLADAMVRALTFADRSVSEEVAAVSRLTTTIVLDAVGRTGTPGPELLSAVR
                     VIEHTWHATLVAWLAGRSSTERVRTDIETACRLIDLTAPREAGAPGSAEGARQGGAEVA
                     HARGARNPAKAPEHAR"
     misc_feature    complement(18926..18939)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     gene            18995..20401
                     /locus_tag="SXIN_RS23125"
     CDS             18995..20401
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572181.1"
                     /locus_tag="SXIN_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_095757461.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1e-28, bitscore:
                     98.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEAAPAAASSPSAGTPGPLAADGGRPLRIALLTYKGNPFCGGQ
                     GVYVRHLSRELAALGHSVEVIGSQPYPVLDETPGPGGVSLTELPSLDLYRQPDPFRTPR
                     PGEYRDWIDALEVATMWTGGFPEPLTFSLRARRHLAARRGAFDVVHDNQTLGYGLLGGP
                     ARLGAPLVTTVHHPITVDRRLDLDAATGPWRRASVRRWYGFTRMQKRVARRLPSVLTVS
                     GTSRDEIVEHLGVPGDRIHVVHIGADTELFSPDPSVPEIPGRIVTTSSADVPLKGLVHL
                     VEALAKLRTEHPGAHLVVVGKRAEDGPVAAAIERYGLADAVEFVKGISDTELADLVRGA
                     QIACVPSLYEGFSLPAAEAMATGTPLVATTGGAIPEVAGEDGETCLAVPPGDAGALAAA
                     LGRLLDPHDGPALRRRLGHAGRERVLSRFTWARAARGTVEHYRRAVERQGAALPAGAAP
                     TAPSTGRPRG"
     gene            20437..21219
                     /locus_tag="SXIN_RS23130"
     CDS             20437..21219
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849815.1"
                     /locus_tag="SXIN_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_019709311.1"
                     /transl_table=11
                     /translation="MLTVDFSRFPLAAGDRVLDLGCGAGRHAFECYRRGAHVVALDRNT
                     EEIREVATWFAAMKEAGEAPAGATATAMEGDALALPFPDDSFDVVIISEVMEHIPDDKG
                     VLAEMVRVLRPGGRIAVTVPRYGPEKVCWALSDAYHEVEGGHIRIYRAGELVRRIREAG
                     LRPYGSHHAHGLHSPYWWLKCAFGVDNDKALPVRAYHKLLVWDIMKKPLLTRVAERALD
                     PLIGKSFVVYATKPRLPDTGPVDGPADAATDGTAEGRA"
     gene            21216..22301
                     /locus_tag="SXIN_RS23135"
     CDS             21216..22301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060427.1"
                     /locus_tag="SXIN_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase"
                     /protein_id="WP_019709312.1"
                     /transl_table=11
                     /translation="MTSPGRTERLVLPGVLTAEQAAATVGGILAHQREDGAIPWFRGHH
                     LDPWDHVEAAMALDAAGEHERAEAAYRWLAEHQLPDGSWYAAYADGDPAAPTDRGRETN
                     FVAYVAVGVWHHYLSTGDETFLDRMWPTVYAAVEFVLALQQPGGQIGWKREAPERDGDA
                     GAAVTDALLTGSSSIHQALRCALAIAEQREDPQPDWELATGLLAHAIRHHPERFLDKSR
                     YSMDWYYPILGGALTGTAAKERIEEGWDDFVVPGLGVRCVLPNPWVTGGESAELALALW
                     AMGESDRAVDILRWIGRLRDDEGMYWTGYVYEDAAFWPEEQTTWTAGSVLLAVAALGGD
                     EATTAVFGGERLPAGLDPDCC"
     gene            complement(22406..22702)
                     /locus_tag="SXIN_RS23140"
     CDS             complement(22406..22702)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976498.1"
                     /locus_tag="SXIN_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_039818594.1"
                     /transl_table=11
                     /translation="MSPYRRSGGSTAAAAIRLVADVAAGILVLWIIMYLLDANRANDLV
                     NFVQNAAHWLAGWSRDLFTMELDWLRVVLNYGLPAVVYLAIGHALAARMPRGA"
ORIGIN
        1 tctgctggac gcggtgggcg gcgtcgtggt ggtggcggcc ggcttcgggg tgcggcacct
       61 gctcatcggc cgtacggcgg agcaggccgg cgcggccggg atcccggagc tcccggaccc
      121 ggcgggcgct gccggcgggg cggacggcgg ggctgccgtg accgggacgg gtgcggacgg
      181 ggagcggtcg gcggccgggc gggggccggg ggcggccccg ggccggggcg cggagccgga
      241 actcgccggg acggccggtg gggagaagac cggtgcgccc ggggagggtt gagcggcggg
      301 agtccgggcc ggagcggggg cgcccggtcg cgcggcggcc cggcatcggc cgccgcgcgg
      361 ggtgagggcc cgtacggacc gggcgcgcgg ccggtccgta cgggtccggc ccgcggtcgg
      421 ggcggagggg accggccgga ccgcgggagc cgtgcggatc agccggtcac ggtgatctgc
      481 gaggccgggt cggtcacatc ggtgacgtca taggtggcgt tgaaggccga ggtctccgcg
      541 ctggtcgggc agccgaagcc gccggtggcc gacaccggga cctgggcgtc ggtgaagtcc
      601 agctgcgagg gggcgccgtt ggtccaggtg ccggccacgg gcgcggcacc gtcgggggcg
      661 gcggtcaccg tgcaggaggc gaggccgctg gtcttcagca cgaagccgcc ctgggggatg
      721 gtcagggtgg cgctgctggg gtcgccgtgc tgcatcgaga caccccagac gccggtggtg
      781 gtgatggtga cactcacccc ggggaggctg gagcggcagg agctgtaggt cggggcgttg
      841 atgacgctct cgaccgggcc ctcggcgttg gtgttgccgg gggcgtccgg gacctggttg
      901 gcgtccgagg tgccgtccgc gacgggcgcg gagctggaga cggtgcaggt gacggtcacc
      961 gcgccggcct tgaaggtcgc cgatccgttg agggtggcgg cgaactggtg tccggcgggg
     1021 gagacggtgg tcggcccggc cgcggtggag tcggccgggg cggcggtggc ggaggcggcg
     1081 ccggtgagcg ccagggcggc ggccgtggcg gctccggtgc cgcaggcgac gagggcgcgc
     1141 agggctaagg ctcgcgtcat ggtgggggtt ctccttgtga gggttggggt gtttcggggt
     1201 gaggggtgtc gtgcggggac gggcccgggg agggctcggc tcccggagcc ggcgggcggt
     1261 tcgggcccgt taccggcgcc ggcgccgggg tggcggccgt tctccggccg tatcccccct
     1321 cgcctgccgc ggcacgggcc gccaggcgaa gatcatggag ccgccgacga tgcccagcac
     1381 ggtgccgatg aagaagccac cgaggttgga catcaccagt gcggcggcgg cgagcaggac
     1441 ggtgacgacg cccgcgaggc cgcggtagtg gggggcgaac caggcgctca gccccatcac
     1501 gatcacgatg agggcgagca ggacggaggg caggcccgcg atcccctggt gcagcatcat
     1561 ctcgacgggg gcgagcggga tgaggctgat ctccagaccg gcgaggacgg tcagcaggcc
     1621 gccccagaag ggacggctgc gccgccaccg ccgccagcgg gcccgtacac cgggccgggt
     1681 gcccggggag ccgccggtca cctccgtacc ggcggccgcg ggggtgccgg gggaggctgc
     1741 ggggcgggcc ggttcggagg gggcacggcc gggcacgtca gaagcactcc gtccggccct
     1801 tgtggatctt catgtgcagc ccggcgagtt tgaaggtgcc ggcggtggtg gcccaggcgg
     1861 tctgcttcag gttcgtcatc cggatgtcgt cggcctgctg cgagaagagg tcctgcatgc
     1921 cctgggcgcc gtccggcccc ttgtcgaggg tggaggcgtc ccggccgatc tcgatgttgt
     1981 tgaaggaggc gttgccggcg agctgggtgg cgtccagcat caggtcggtg gcctcgacct
     2041 tcttcttccc ggtgcccgcc gagagcttga gcgagatgtc gccgacgacc ggcaggctgg
     2101 tgacgacgga ctggcagaga ttggtcatct ccgccttccg caggccggtc acggccacgg
     2161 gcagcagctc gtcccggacg ttggtgtcga aactgccgta ctggacgaag ccgtccccgg
     2221 tgagttcgtc ggcggagacc ttgaactcct ggccggagac ggcgaacgag gcggcgagcg
     2281 ccccgttggc cagcgcgacg gcgagcgccg cggtggccgc gaatcccggg accgcgagta
     2341 acgcgaatct ccgcagtccg acgcggccgg tctcgtatcc gtccgcgtcg tccctgctcc
     2401 gaacgtcttc catggtctgt ccctccgtcg gtggaacggg gtcagcgcct cggaccgcgc
     2461 gtcagcggtg cgtgtggggg aggtggtgcg gctctgtgcg cggtgcgaag gggcgcatgg
     2521 gtgcagtgtt gagtgcatgc caagccgtgg gttaccgagg gtatgactcg ccagtaacct
     2581 tggcaagacc gcggcggagc cggattcccg gggaccggcc cggaggggtg gagcgccccg
     2641 tcgggccggc tgaggggcgc ggccgcacgc cgcgggccgc gcggggcggc cggcccgggc
     2701 tcagggccgt tcgaacgcca ccggggcctc gaaggccgcc cggcgggtag cgcggcgcag
     2761 ggccgccagg acggtggagc cgagggtgag ggtcagcacc acggtcagcg cggcccgggg
     2821 aagatcccag ccgagggagg tcgccaggca gtacgcggcg aagcggacga ggttctcgtg
     2881 caccgggtcg cccgggacga aggagatgcc cgtccccagc ccgccgatgt acggccagcc
     2941 ctggaggttc atcaccgtgc cgtagaggac ggccgcggcc ccgccgtacg cggccagcag
     3001 ccaccgctcc gcccggccgc gcagcccttc cgcccccggc agcagcccgg cgcccatcgc
     3061 cacccagccc atcgacagca tctggaacgg catccagggc cccaccccgc cggtcagcag
     3121 ggccgaggcg aacatcgtca ccgcgccgag cacgaaaccg aagcccgggc cgagcacccg
     3181 gccgctcagc accatcagga agaacatcgg ctccagcccg gcggtgcccg cgcccagcgg
     3241 ccgcagcgcc gcgccggccg ccgcgagcac acccagcatc gcgatggcct tggcgtccag
     3301 cccggtgtcg gcgacggtcg ccaccacgac ggccaccagc agcggcagca gcgccgcgaa
     3361 cagccacggc gcgtcgcccg agtgcgccag cccggacgcg gagtcggcga gcagcggcca
     3421 gccgaaggcc atcaccccga tcgcgctgac gagcacgagc gccgcgaccg agcgcgggcc
     3481 gagacgcacc gcccgcaccc ggccggccgc cggccgctcc cgggccggcg ggagctgcgg
     3541 ggtcatcggg cggcctccgt ccggggggtg ccgggatcat ccgggctgtc cgggctgtcc
     3601 gggctgtccg gggcggccag ggcgtcccgc acctgggaga cggtgagcca cggctgcggc
     3661 gccaggatct tggagacctg cggggagaag gccggggagg cggtgacgac ctcggcggtc
     3721 gggccgtccg cgaccacctc gccgtccgcc aggatcacca cccggtgcgc cagttcggcg
     3781 acgagctcca cgtcgtgggt cgccagcagg acggcgtgcc cttccgccgc cagtccgcgc
     3841 aggatctcca ccagccgtga cttggcggcg tagtcgaggc cgcgggtcgg ctcgtcgagc
     3901 agcagcagcg gcgggcgtgc cgtcagcacg acggccagag cgagcgccag ccgctgcccc
     3961 tcggagaggt cgcgcggatg ggtggtgtcg gagacgtccg gcagcagggc ggtgaccagg
     4021 gcccggcagc tgcccggctc ggcgtccgcg tccccgtccg ccgccgcgca ctccgccgcg
     4081 accgtgtcgg cgtagaggag gtcccgcggc tcctgcggta cgagcccgac gcggcggatc
     4141 aggtcgcgcg ggggtgtgcg gtgcgggacg gcgccgccgg cgagggccgt gccgcccgcc
     4201 gggcggtgca gcccggcgag ggtgttgagc agggtcgact tgcccgcgcc gttgcggccc
     4261 atgagggcca ccgtctcgcc gggccgcacg gtcagcccga tccggcgcag cacctcggtg
     4321 cggccgcgcc gcaccgacag ccgggacagc tcggcggcgg gagtggtatc cggggcggtt
     4381 ccggcggtcc ccgcggtggc cccggtggcg gccgggtgcg gggcgcgaac cgggtacggg
     4441 tccggggcga gccccgccag ccgttcccgc agcgggcccg cggtccgccg cgcgtcccgt
     4501 accgacagcg gcagcggaga ccagccggcg agccgcccca gggcgacgac cggcggcgtc
     4561 accggggaca cggccatgat ctccgccgga ccgcccgtca ccggggccgc gccgggcgcg
     4621 ggcagcagga tgacctggtc cgcgtagtgc acgacccgct ccagccggtg ctcggccatc
     4681 agcaccgtcg tgcccaggtc gtgcaccagc cgctggagga ccgcgagcac ctcctcggcg
     4741 gcggccgggt cgagcgcgga ggtcggctcg tccagcacca gcacccgcgg atgcggggtc
     4801 aggacggatc cgatcgcgac ccgctgctgc tggccgccgg acagggtggc gatgggacgg
     4861 tcgcggagcg cggcgaggcc gagcaggtcg agggtctcct cgacgcggcg gcgcatcacg
     4921 gccggggcga ggcccaggga ctccatgccg tacgccagtt cgtcctcgac ggtgtcggtg
     4981 acgaagtggg cgagcgggtc ctggccgacg gtgccgacga cgtccgccag ctcgcgcggc
     5041 ctgtgggtgc gggtgtcgcg gcccgcgacc gtgacccggc cgcgcagggt gccgccggtg
     5101 aagtgcggga cgagaccgct gaccgtgccc agcagtgtcg acttgccgac accggagggg
     5161 ccgacgagaa ggcacaactc gccctcgggg accgtcagat ccacaccggt gagcgccggt
     5221 ccggcggctg cgccctcgta gtggaccgac acgtcgtcga accggatcac gctgtctcct
     5281 ccggtgggat ggcggacgcg gtgcggcggc gctccgcgcg gtgcggcgga ccgggacgct
     5341 ccgggcggtc cggggcggcg gaaggcccgg ggcgcccgcc gccggcttca ccgccgcccc
     5401 cggagcgcca cccggagccc ggcggggtgg acgaggccgg cggagcgccc ggcgcgcaag
     5461 gacccggggc ggcaccggga gccccgtccg gggtgccgga attcggcggc gcggctccgt
     5521 ccgccgggcc gtccgccggg ccgtgttccg ggcccgtccg gcccgggcgg aggcgccagg
     5581 cggcgacggc cccgtccgga acggcgtccc ggtcccggtc ccggtcccgg tcgcggtccg
     5641 ggtccaggtc cggggccccg gacccgcggg cccgctcgga ccgctcgccc ggctccgcgc
     5701 cccccgacgc ggaggcggca tcgaacggtc cggttccgcc cggcccgccg cggcgggtcc
     5761 gggacgcggg cgccggggcg gccacggccg ggagcagccc cagcaggacg ccggccgcgg
     5821 gccacagggg gagggccggt gccgtcagcg ggacgaccga cgggtgcagg tccgcccggc
     5881 cggcggaggc ggaccagatc atcaccgcgg ccaccgccgc cccggacccg gcgaccagcc
     5941 aggagcgcgg gccccagcgg tccggccggt agcggctgcg caccgagcgg cggccgccca
     6001 gccacagccc ggccagtgcg gcggacagcc ccagcagcag gacgggcagg ccgaaccccg
     6061 cgccctccgc ggccagcaga ccgtaggtgc cggcgcagac gccgaggagc ccgccgaggg
     6121 tcagcaccgt cgtggtgtgc cgtacggcgg ccgggacgcg ggcggtgcgg ccgtagccgc
     6181 gcgcgtccat cgcggcggcc agcgcgacgg accgctccag cgctccctcc agcaccggca
     6241 gcgcgatctg gaggatcgcc ccgacgcccc ggtcggcgcg cccgcgcagc ctgcgtgcgg
     6301 cgcgcagccg caccacgtcg gcgaccaggt tgggggcgaa ggtcatggcg acgacgacgg
     6361 cgacgcccgc ctcgtacagc gcgcccggca gcgacttgag cagccgcgcc gggttcgcca
     6421 gcgcgttcgc cgcgccgacg caggccagca gcacggccag cttgaggccg tcgtagaagg
     6481 cgaaggcgag cccctcggcg gtgacccggc cgccgatccg caccccgcgc gcccactccg
     6541 gcagcggcac ctcgggcagc gtgaagagca cctggctgcc ggggatcggc gagccgagga
     6601 agaccgagaa gaccagccgg atcgcgatca ccaccaggcc gagcttgagg aacgcgctgt
     6661 agctgcgcgc ccagggggcg tcggtgcgcc gcgcggcgac gacatagccg gcgacggtgg
     6721 cgagcagggc cagcagcagc ggattggtgg tccgggacgc ggcggtggcc agacccaggg
     6781 cccacagcca ccaggccccg gcgtgcaggg cgttgccgcg cgaggcctcc ggcgcccggg
     6841 acgcgagacg cccgcggagc cgcgccaccg cggacggagc cgcgcccgtc ccctccgcgc
     6901 cgggcagccg ggccgcgccg tccgtgcccc gctccggccg ccgggaccgg ggcacggcgg
     6961 ccgtcgcggg gcgcggcgga acggcaccgc ggcccgccgc gggccgggcg ctgtcgagag
     7021 ggccgggacg gggcgtcccg ggggcgccgg ggctcatccg cggcgtcggc gggcctgcca
     7081 ggcggcgccc gcggcgagga cggcgacggc ggcggcaccc gcgtagagac cggtggacga
     7141 gccgccgccg tccccgccgg ccggctcacc ggcacggtcg tcaccggcac ggtcgtcacc
     7201 cgagccgccg ggaccgcttc cgccggccgg gtccgcgccg ccgtccccgg cacccgcctc
     7261 cccggacacc tgttcgccgc agccgcgctc cgggtagccc gcgatcgcgc acagcagcgc
     7321 cgaggtgttg tagcggagcg gcttcgcgac ggcggccagg gcctcgccgc tggtcgcgtc
     7381 ctccggcacg gacgcgcact ccgtgcgggg ctccgggggc cgttcgccgt ccggcgcgtc
     7441 ctcggcggta ccgaagtcca gcacgagcgc gaccctcttg cggccgtcct cggcgggggt
     7501 gtccgcgcag acggcgtcga agccggcggt gccgcgcggc ttcgcggcgt cctgggtgtt
     7561 gacgctcacc gagaagcgga agccctcgac gtcgccgtcg gcgggccggg ccgtcgccgg
     7621 cccctcggtg gcgtagctcc aactgccccc gtcccgctgc cagaacgacc agtagcggta
     7681 cccctcggcc tgcgccggcc ccgcgccgag cgcggtgacg gcggccacga gcagcagcac
     7741 ggccgacccg cgcaccccgg ggcgcgcggc cggacgccgg cgggcgccgg cccggggacg
     7801 gccggcgccg cgcggcaccg tgccgtgccg gccgccgctc ggccgcgtgc cgtgccggcc
     7861 gccgctcggc cgcgtgccgt gccggccgcc gctccgccgc gtgtcacccg ggccgctgcc
     7921 gtgcggctgc tccgctccgt ccgtctcccg gccgagcggc cccgtccggt gcggccggga
     7981 gccgtaccgg tccgtgccct ccggtgtccg gagtccggtg ctccgccgtg gccgcccgct
     8041 cacgaccgct tcctgcggcc ggcggtgagc atcaggacgg cgccggcgac gagccccgcg
     8101 agcacgcccg cgcccaggat ccaccagagg acggagacgt cgccggaccc ggacttctcg
     8161 ccctcctcgg aggcgtccgc gccggccgcc ggaaccgact ccggctccgg cccggtggcg
     8221 ttgagctcct tcaccaggtc cgtgccgccg aaggagcgcg ggtcgccgcc cgcggcgtgc
     8281 gcggcgagaa ccagggtgcc cagaccggcc gggttgtccg cggcccactc ggcggagttc
     8341 ttctccagcc aggccagcgg cgcctcggcc gcctccggcc ggccggccgc caccagggcg
     8401 atcacggcct cggcggtgtt ggagtggtcc ggcaccggct cgtcggcacc gggcgcgagc
     8461 gaggtgaggt gcccgtcctt ctccagcagc ccggtgaggt acgcggcggc gccggacgcg
     8521 gcctcctccg gcgtacggcc ggcgtccgcg ccggagccgc actccagcgg ctcgggcgca
     8581 ccgccgtcct cgccgccgtc cccggtggcc ggggtgacgg ccaggccctc gccgtggccg
     8641 gcgaggacac cggccaccgt ggcgtcggcg ttggccagga ggcggccctt cttgtcgggc
     8701 tggaaggcgt aggcgccgcg gtcaccggcg tcggcgtcgc agccgagctg cagctccgcg
     8761 agcgcgtcgt acggggactt gccgccggcc cgggcggctc ccggcttctc gccagccgcg
     8821 gccagcgcgc cgacgaccac ggaggtggag ttggtgtcgc tgggggtccc cgggaggtag
     8881 ccccagccgc cgtcctcgtt ctgcacggac ttcagccagc cgacggcctt gcggacctca
     8941 ccggtgtgcc cgccgagagc cgccagcgcc tggacggcga cggcggtggc gttgctgtcc
     9001 accggtgtct tggcgtcgca ctcggcgccg gcgtccgcgc ggtacgcggc gaacgcgccg
     9061 gaggagcact gctgcccggt gagccagtcc acggcttcgg cggccggggt gacgcccgcg
     9121 gtgtcctggg cgagcagggc tatggactgc cgccacaccc cgtcgtaggc cgggtccttg
     9181 gtgccgtgca gcccggacgg cggcttcggg gcgggggagg aggacggcgc ggcggtgccg
     9241 gccgaggcgg cgggtgcggc gagcgcaccc agcacggcgg acgcggccag ggccgcggcg
     9301 gtgcggcgta cgttcatggt tttggtgcct tccgttggcg gttctcgtgg cggggggcag
     9361 ccgggcacgg ccgaccccgg ccgcgcggac cgcacgcgga gggcacaccg ggctcgtctt
     9421 ccgtagacct cgacggtgcc gtccgcggcc gggcgcccag gagggcgccg caccggcgga
     9481 cgggagcctg ttcgcgcccg gacaggtgct ccggctcgta cggccgcgcg gggcgcgggg
     9541 tgtactcacg gttgcgggtc agcgccggat tcgcaccggt cttcccctgt cagggcacgg
     9601 atgaagttgt cgggagacac cctaaccggc cggtagaaga tcatcgaacg ggtgtccgcc
     9661 cagcccgccg gcagggggcg cggagccctc cgaagggagt gccggacggg gggagcggcc
     9721 gggcgggtgc gggcgtcccg ccctcccggt gcccgcccgt gtccgggccg cggccgtccg
     9781 gggcgggcgt cacccaggcg catgaccggt atgaccccag gtcagaggtc gttcggaggt
     9841 gcgagagggc gccgttcgac gggattcgaa ctgccgtaac ttactcatgc gttccgcaca
     9901 tcagggtcgt gacagctgtg actgttccgc cggcgccccc cggtgacaag ctcgaatcac
     9961 accgagaggc ccgcaccacc ggacgggacg aaggagcgtc atggacctgg ggtacgccgt
    10021 gtactgcgac gcggaccgca cgttctacga cgccccgcac cggctctccg ccggcaccga
    10081 ggacaccccc ggagcgcccg gcgccctcta cgagcacgcc cgccgcgagg ccctcgaggg
    10141 atggcagcgg cacagcaacg gcgactggct cgccttccgc ccgctcgaca cctcgctgcc
    10201 cgcccagggc tggaagatcc acgtctcggc cacgctcgac aacgccgaga agatcctcac
    10261 ccaggtctgg gactactgcg tgccgcggtc ggtggccttc aagttcatac cgggccggca
    10321 cctcctccgc acccgcaacg ccaagtacgc ggaccggggc ggcagcggca agttcatcac
    10381 cgtctacccg gagaacgacg agcagttcgg gaccatcgcc cgcgagctcg gcgaactcct
    10441 cgacggggag cccggcccgt acatcctcag cgatctgcgc tggggcgccg gcccggtcca
    10501 cgtgcgctac ggcagcttca ccgaacggca ctgctacgac gagcagggcg tcctgcgccc
    10561 cgccgtggag aacgccgagg ggaagctcgt acccgaccgc cgggaccccg ccttccacat
    10621 acccggctgg gtggagcccc cggcctgcct cgccccgcac atcgaggccc gcacggccac
    10681 ccgcaccacc ggcatcccgt accgcatcga gaaggccctg cacttctcca acggcggcgg
    10741 tgtctacgcc gggacggaca cccgcaccgg cgagaaggtc gtcctcaagg aggcccggcc
    10801 ccacgcgggt ctcgcggccg acggagccga cgccgtgagc cggctggagc gcgaacgcgc
    10861 cgccctcgaa cgcctgtcgg ggctgccgta caccccggag gtgcgcgact ccttcgtcct
    10921 cggcgaccac cacttcatgg tgatggagtt cctggagggc aagccgctca acacgttctt
    10981 cgcccgccgg cacccgctca tcgaggccga ccccgcaccg gaggcgctcg ccgggtacac
    11041 ggactgggcg atacggatgc acggcctggt gaccgaggcc gtggaggcgg tccatgcccg
    11101 cggcgtcgtc ttcaacgacc tgcatctgtt caacatcatg gtctccgagg acgagtcctc
    11161 cgtcgccctc ctcgacttcg aggccgccgc gcacatcgac gagggccgcc gccaggtggt
    11221 cgccaacccg ggcttcgtcg ccccggccgg gcaccgcggc ttcgacgtgg accgctatgc
    11281 gctcgcctgt ctgcgcatcg ccctcttcct cccgctcacg agcctcttcg ccatcgaccg
    11341 cggcaaggcc gcgcatctcg cggagatcgc cgcccgggag ttcccggtgg cccgcggctt
    11401 cctcgacgag gcggtcgccg agatcctccg cgaccccgcc gcgcagccgc cggcggccgg
    11461 agcggacgag acggccggca gcgccccggc ggcccgcgcc ccgtatctgc ccgtcgaccc
    11521 cgcggactgg ccgcacagcc gggactccat ggtccgcgcc atcctcgcct cggccacccc
    11581 ggaccgccac gaccgctact tcccgggcga catcgcccag ttccgggcgg gcggcggcct
    11641 ctgctacggc tacggcgcgg ccggcgtcct gcacgccctc gccgagaccg gcggcggacg
    11701 gcacccggag gcggaggagt ggctgctgcg ccgcaccgaa cgccccgctc ccggaacccc
    11761 gttgggtttc tacgacggac tcgccggcat cgcctggacc ctggaccgcc tcggccaccg
    11821 ggaacgcgcc ctggaactgg ccgggctcac cctcgccgag gactggtccg gcatggcgcc
    11881 cgacctgcac agcggcctcg ccggcatcgc cctcgccctg gactccctgg gcgcgagcac
    11941 gggcgagatc gccctggagg acgcggccgc gcgctgcacc cggatcgtcg cggaccggtt
    12001 cgcccgctcc gacggcaccg agggcgccac cggcggcggc accggacgga ccggcggcgg
    12061 agtgccgcgc gccgggctcc tccacggcgc cgccggccag gccctgctct tcctccgccg
    12121 gtacgagcgc accggggacc ccgtgctgct ggacctcgcg gccgaggccc tgcgccgtga
    12181 cctcgctcgc tgcgtcaagg gccccgacgg cgcgctccag gtcgacgagg gcaagcgcac
    12241 catgccctac ctcggcgccg gcagcgccgg catcggcatg gtcctcgacg actacctggc
    12301 ccaccgccac gacgaggact tcgaccgggc gcgccgcgac atcgtgcggg ccgcccaggg
    12361 caagttctac gcccagcccg ggctgttccg gggcgcggcc ggcatggtcc tgcacctggc
    12421 ccgcaccacc accggcggcc cgggcacgga cgagaccgcc ctgcgccgcc agatcaccgc
    12481 cctcacctgg ggcgccgtcc cgttccgcgg ggaactcgcc ttccccgggg agcagatgat
    12541 gcgcctctcc atggacctca gcacaggcac cgccgggtgc ctgctcgccc tgggcagcgc
    12601 gctgcacggc tctcccgtgc acctgccctt cctcccgccg cccgccgggc ggccccacga
    12661 gccggtctcc gccggaggcc gtacccaaga aaatcccgtc cccacggaca tcaaggaaag
    12721 gacagtgtca tgacccttct cgacctgcag accatggaga cccccgccga ggagatcacc
    12781 ggcgagctgg cgacgggcgg cggctcccgc gcctccctgc tgctctgcgg cgacagctcc
    12841 ctgagcgtca ccacctgcaa ctgatctgag ccgctagccg gcaggtcagc tcagcgcggt
    12901 cccgggcggc ggcattccgc ccggggccgc acgctcaccg tacgcgccgc cttcgtccgc
    12961 gcgtcaccgg aggaggggag acaccgcagc ccatggccac cgagccggcc ggcaccggcc
    13021 cctccgccga agcccggaac accggggacc gctcccccgg cgcaccggcc gtcaccccgg
    13081 gcgaggaacc acgcggcgcg gaaccacgcg gcgcggaacc acgcggcgcg gaaccacgcg
    13141 gcgcggaagc ccgcgagagg gcccgcaccg ggaaggcccc caacggcaag acccgcaacg
    13201 gcaagacccg caccgggaag gcccccaacg gcagggcccg gaccgccggt gcccgccgcc
    13261 acgacgaggc ccgtacccct ccggccgccg ccggcgcctc tcccgcggac ccggcccccg
    13321 gcgcccgccg gctgctggcc ggcgccgcgc gccgcagcac cggccgggcc gtcctgatcc
    13381 tcctcgccac cacggcctcc gccgccgcga ccatcgcgct gcccgccgtg ctcggccaca
    13441 ccctcgacct gctgctcgcc gggcgggacg gagcccagcc gtgggtggcg ctctgcggcg
    13501 tgctgctcgc ggccgaggtc ctgctcgacg cgctcaccgc ccacgccacc ggcgtcacca
    13561 acgcccgctc cacggcctgg ctgcgcaacc ggggcaccgc ccacctcctc tccgtcggcc
    13621 cgcgccgcgc cgcccgcttc accccgggcg acgtcgtgac ccggctgacc ggcaacgcgg
    13681 ccgaggcggg cacggtcccc gccaccgcgg ccgcctccgc cgcctcgctg ctcacgccgg
    13741 tcggcggcat cgtcgccctc gtcctcgtcg acgtctggac cgccgccgtg ttcctcgccg
    13801 gggtgcccgt cctcctgctg cttctgcggg ttttcgtccg cagctcctcc gacagcgtga
    13861 cgcgctacca gcgcatccag ggagacatcg cggcccggct gatggaggca ctcggcggcg
    13921 cgcggaccgt cgcggccgcc ggtacggcgc gccgtgagcg ggaccgggtg ctcgcgcccc
    13981 tccccgaact cgacgcccag gggcgccgga tgtggcaggt ctacggccgc gccgtcaccc
    14041 agggcggcat cctggtgccg ctgctgacca ccgccgtcct ggccgtcggc ggagtgcggc
    14101 tggccgccgg gcagctcagc gtcggcgaac tcctggccgc ctcccgctac gcgggcctcg
    14161 ccgccgggat cggcgccgtc gtcagccagc tcagcgccct ggtgcgcggc cgggccgccg
    14221 cccgccgcac cgccgaactg ctgtccgcgc cgcgcgtgcg ccacggcacc cgccgtctgc
    14281 cgcccggcgg tcccggccgg ctcgaactgc gcggcgtcac cgtcgtccgg ggcggcgccc
    14341 gggtgctcga cggcgtcgac ctcaccgtcc ccggcggcgt cacggccgcc gtcgtcgggc
    14401 gctccggcgc cggcaagtcg gtcctggccg ccgtggccgg ccggctggag gacccggacg
    14461 gcggcaccgt cctgctggac ggcgtgccgc tgcccgacct cgaccgggcg gagctgcgcc
    14521 gcgaggtcgg ctacgccttc gaacgcccgg cgctgttcgg cggcaccgtg ggcggggcca
    14581 tcgccttcgg cgccggcgag cccccggagg agaccgtacg gtccgccgcc cgcaccgcgc
    14641 gcgcggactc cttcatccgc ctgctgcccg ccggctacgc cacccggctc gccgacgcgc
    14701 cgctctccgg cggcgagctc caacgcctcg gactggcacg ggcgttcgcc cacgccggcc
    14761 ggctgctggt gctggacgac gccacctcca gcctggacag cgtcaccgag ctggaggtgg
    14821 gccgcgccct gacccgggac gtacgggccg gcacccgcct gctcatcgcc caccgggtct
    14881 cctcggcggc ccgcgccgac ctggtggtct ggctggagaa cgggcgcgtc cgcgccgtgg
    14941 ggccgcacga ggtcctgtgg gaacgccccg cgtaccgcgc ggtcttcgcc ggcactggca
    15001 gcggcaccgg caccgacgcc gaagcgcccg acccgcccgg cccggcggtc accggtgctc
    15061 cgggccccgt tcccggcggc cggggccgga cggggggtgc cccgtgaccc ggcccggaga
    15121 agacccggca gtgcggccgc ggccccggtc cgggaaggac cgggccgggc ggggggcgct
    15181 gcggcggatc ctgccgcagg cgcgccggtt cctcggggcg cggctccgcg tcctggccgc
    15241 gctcggcggc tggtcgctgc tggagtcggc gcacaccttc ctcggcggct acagcgtggc
    15301 gcaggccctc gaccgcggct tcctcgccgg ggacacccgc accggactcc tctggctggc
    15361 cgtggccgcc gcggccgtcg tcgtcggagg cttcgccaac cagggcgtgt tccgcgggct
    15421 ggccggcctc gtcgaacccc tgcgcgacgg gctgctgcgc cgggtggtgt cggcctccct
    15481 gcgcgaggcg gtcgccgatc cggcgcgggc cgacagcgcc gtcgtctccc ggatcaccca
    15541 ccagacggag accgcccggg acagtttcgc cggactggtg ctggtggccc gctccttcct
    15601 gttcaccgcc gccggcgccc tgctcgggct ggcctccctc gcccccctgc tgctgctcgt
    15661 cgtcgggccg ccgctgctgc tgggcctggc cctgttcctc gccacgctga tcccgatggc
    15721 cgcccggcag cgcgactacc tccgcgcgga cgaggcgctc gccgaggagt acggggccgt
    15781 cgccggaggt gtccgggaca tcgtggcctg cggtgccgag gaccgtacgg ctgcgcgggc
    15841 cgcgcggctc gccgacgccg agctgggcgc cgcgcggtcg ctcgcccggt gggccgcggc
    15901 gcgcaccctg tcgctcgggg tggccggaca actgcccgtc ctgctgctgg tcttcgcgac
    15961 gccctggctg ctggacaggg gtgtcacggc cggtgaactg ctgggcgcgc tcacctacct
    16021 gacgcagtcg ctgctgcccg cgctgcacac cctgatgacg gcgctgggcg ccgcgggcac
    16081 ccggctgctg gtgatcctgg accggctcac cggcggccac gacggaccac cgggcgcgga
    16141 gacgcccggc cccggggcgc ccggctccgt caagggccgc gccgcggtac cgcatccgga
    16201 cgcggccttc tcggcggcgc ccccggtccc gatcgcggtc ccgatcgcgg tcccgatcgc
    16261 ggtcccgatc gcggggccgg acggcgggcc ggagccgggc gcgccggccg tcgaactccg
    16321 ttcggtcacc ttcgcctacg gcgccggggc gcaccccgtg ctgcgcgatc tggacctcac
    16381 cgtcggggcg ggggagtgcc tggcggtggt cgggccgagc ggcatcggca agtccaccct
    16441 gaccggcctg gtcgccgggc tgctgacgcc cggccggggg gaggtccggg tgctcggccg
    16501 ccccgcccgc gcgtggccgg ccggggaacc cgcgcgcctg cgggtcctca tcccccagca
    16561 ggcgtacgtc ttcaccggca ccctgcggga gaacctgctc tacctctgcc cggacggcgc
    16621 cccgccggag gcggtgagcg catcggcgga ggcggtgggc ctgaccgggc tggcggaccg
    16681 gctcggcggt ctcgacgccg tcgtcgaccc cgccgtgctg tcgcaggggg agcggcagtt
    16741 gatcgccctg gcccgggcac atctgtcccc cgccccggtg gtgctgctgg acgaggcgac
    16801 ctgccatctg gacccggtgg ccgaggagcg ggccgagcgc gcgttcgcgg agcggccggg
    16861 cacggtcatc acggtcgcgc accggatcag ctcggcccgc cgggccgacc gggtgctggt
    16921 gatggacggg gtgcacgcgg tctgcggcag ccacgacgaa ctgctggacc gctccggcct
    16981 ctaccgcgat ctcgtgggcc actggcagac cgtgcgcgtc tgacggtgcg cccgggaggc
    17041 ccggaaggtc cgccgcccgc cgcccctgcc ccgtcggcct cgacggggca ggggcggcgg
    17101 gcggggcagg actcagaccc agccggcgct ctgcgatatg cgaacggcgt cgatgcggtt
    17161 tctcgcaccg gtcttgcgga tcaccgaggc catgtagttg cgcacggtcc cgttgcacag
    17221 gtgcaggctc ttggcgatct cggcgatcgg cgcgccctcg gcggccaggg agagcacgct
    17281 cagctcgcgt gccgtcagcg gcatctcggc cgcctgcatg aagccgaaag cgagcgattc
    17341 gtccacgaat cgctcgccct tggacacctt gcggatggcg tccagtaatc gctgcggggt
    17401 cgcgttcttg ctgacgtacc ccagggcgct ggcgtcgaag gcgcggcgga gcgcgcccgg
    17461 ccgtcccgcg gtcaccaggg cgagcagcgc gctgcggcgg ccggaccgga gcccctgggc
    17521 cccccggccc tccggttcgg cggcttccag gaccgcggtg agcgagtccg aggccgggtt
    17581 gtcggcgtcg accacgcaga cgtccggacg ggtggcttgc gctcgcgccg ggaacttgtc
    17641 ccaggtcgcc gccgtgactt ccaaatcgtg ctccctcccc agcagtgcgg ccagcgccga
    17701 ccgcagaagc ccgatgtcgt gcaccagaag tacccggatc acttgcccgt cccctccaga
    17761 ctcgtgtgca ccggtggtct cccatgtgtc cgtctatgtc cgtcggaaca tctgatgagt
    17821 tgagtcgtcc aagagcgcgt tcccacaacg cgggcgaggg aacggacgac acgggacttg
    17881 gcgtacggac ttgccctacg tcccgtgctg tagtcggttc agcgggcgtg ttccggagct
    17941 tttgcggggt ttcgcgcgcc cctcgcatgc gccacctccg cgcccccctg gcgcgcccct
    18001 tccgcgcttc ccggtgcccc cgcctcccgc ggggccgtga ggtcgatgag ccggcaggcg
    18061 gtctcgatgt cggtgcgcac cctctccgtg gaggaacggc ccgccagcca ggccacgagc
    18121 gtcgcgtgcc aggtgtgctc gatgacgcgg accgccgaga gcagttcggg gcccggggtg
    18181 ccggtccgcc ccacggcgtc caggacgatc gtggtggtca gccgggacac ggcggccacc
    18241 tcctcgctca ccgaccggtc ggcgaaggtc agcgcccgca ccatcgcgtc cgccagcagc
    18301 ggctcgcgcc gcatcgcccg gaaggcgcgc agcacggttt cggccacccg ggccgagggc
    18361 gcctccgcgg ccacgggtct tctcgccggt gtctcgtaca gccgctgcaa ctggtcccgc
    18421 agcgtggcga ccagcagatg gatcttggac gggaagtagc ggtagagggt gccgagggcg
    18481 accccggagc tctccgccac ctcgcgcatc tgcacggcgt cgaagccgcc ccggctcgcg
    18541 agttcggcac tcgcacgcag gatcgaccga cgacgtgctt cctgacgctc cgtcaggcgc
    18601 gatggggaga gctgtgacgc tgattccgtg gccatatgtc ccgatccgtg acatctccgg
    18661 tgtgcgccgc catccgcagg ggcacctcac cgtgcccgag tgctcacggc gggcgcaagc
    18721 tcagggcatg gctccggagg tgcggaaagg cccgacggcg cgccgaccgt ggtgcgaatc
    18781 acccggcccg gaccggcggt aagggctacc tgccggtaga ttcgaagctc ctcccacggc
    18841 ggacgaccac ggcgggcgac cacgcggacg gccgggcgga cagccgggcg gggtgacgga
    18901 cgggcggccg ggcggccggc caagctgaaa cttgttctag attggcgcga gccgctacgc
    18961 tccggcagaa ctgaagtgag aaggggcccg aagagtgacc gctgaggccg caccggcagc
    19021 cgcatcgagc ccctccgccg gaacccccgg ccctctcgcg gccgacggcg gacgcccgct
    19081 gcgcatcgcg ctcctcacgt acaagggcaa ccccttctgc ggcggccagg gcgtctacgt
    19141 ccggcacctc tcccgcgaac tcgccgcgct cggccactcc gtcgaggtca tcggctccca
    19201 gccctacccg gtcctcgacg agacccccgg ccccggcggg gtgagcctca ccgagctgcc
    19261 cagcctcgac ctctaccggc agcccgaccc gttccgcacc cccaggcccg gcgagtaccg
    19321 cgactggatc gacgccctgg aagtggccac catgtggacc ggcggcttcc ccgaaccgct
    19381 caccttcagc ctccgcgccc gccgccatct cgcggcccgc cggggcgcgt tcgacgtggt
    19441 ccacgacaac cagaccctcg gctacggcct gctcggcggc cccgcccggc tcggcgcccc
    19501 gctcgtcacc accgtccacc accccatcac cgtggaccgg cggctcgacc tcgacgccgc
    19561 caccggaccc tggcgccgcg cctccgtccg ccgctggtac ggcttcaccc gcatgcagaa
    19621 gcgcgtcgcc cgccggctgc cgtccgtact gaccgtctcc ggcacctccc gcgacgagat
    19681 cgtggaacac ctcggcgtgc ccggggaccg catccacgtc gtccacatcg gcgccgacac
    19741 cgaactgttc tccccggacc cctcggtccc cgagatcccc ggccggatcg tcaccacctc
    19801 cagcgccgac gtccctctca agggcctggt ccacctcgtc gaggcgctcg ccaagctccg
    19861 caccgagcac cccggcgccc atctggtcgt cgtcggcaag cgcgccgagg acgggcccgt
    19921 cgccgccgcc atcgaacgct acgggctcgc cgacgccgtc gagttcgtca agggcatcag
    19981 cgacaccgaa ctggccgacc tcgtgcgcgg cgcccagatc gcctgcgtgc cctccctcta
    20041 cgagggcttc tccctgcccg ccgccgaggc catggccacc ggcaccccgc tggtcgccac
    20101 caccggcggg gccatccccg aggtcgccgg cgaggacggc gagacctgcc tggccgtacc
    20161 gccgggcgac gccggagccc tcgccgccgc gctcggccgg ctgctcgacc cccacgacgg
    20221 ccccgcgctg cgccgccgcc tcggccacgc cggccgggaa cgcgtgctct cccgcttcac
    20281 ctgggcccgc gccgcccgcg gcaccgtcga gcactaccgg cgggccgtgg agcggcaggg
    20341 cgccgccctc ccggccggag ccgcccccac cgccccttcc accggccgtc cgcgcggctg
    20401 accggacgcc ccccgaccga aagaggcaga ccccgagtgc tgaccgtcga cttttcccgg
    20461 tttccgctgg ccgcgggcga ccgcgtgctc gatctcggct gcggcgcggg ccggcacgcc
    20521 ttcgagtgct accggcgggg cgcgcacgtc gtggcgctcg accgcaacac cgaggagatc
    20581 cgcgaggtcg ccacctggtt cgccgccatg aaggaggcgg gcgaggcccc ggccggcgcc
    20641 accgccaccg ccatggaggg cgacgcgctg gcactgccct tccccgacga cagcttcgac
    20701 gtcgtcatca tctccgaggt gatggaacac atccccgatg acaagggtgt gctcgccgag
    20761 atggtccgcg tcctccggcc cggcggccgg atcgccgtga ccgtcccccg ctacgggccg
    20821 gagaaggtct gctgggcgct ctccgacgcg taccacgagg tcgagggcgg ccacatccgc
    20881 atctaccgcg ccggggaact ggtccgcagg atccgcgagg ccgggctgcg cccctacggc
    20941 agccaccacg cgcacgggct gcactcgccc tactggtggc tgaaatgcgc cttcggcgtc
    21001 gacaacgaca aggcgctgcc cgtccgcgcc taccacaagc tgctggtctg ggacatcatg
    21061 aagaagccgc tgctcacccg ggtcgccgaa cgcgcgctcg acccgctgat cggcaagagc
    21121 ttcgtcgtct acgccaccaa gccgcggctc ccggacaccg gccccgtcga cggcccggcc
    21181 gacgcggcca ccgacggcac cgccgagggc cgggcgtgac cagccccggc cgcaccgaac
    21241 gcctggtcct gcccggggtc ctcaccgccg agcaggccgc cgccaccgtg ggcggcatcc
    21301 tcgcccacca gcgcgaggac ggcgccatcc cgtggttccg cggccaccac ctcgacccct
    21361 gggaccacgt cgaggccgcc atggccctcg acgccgccgg tgaacacgag cgggccgagg
    21421 ccgcctaccg ctggctggcc gaacaccagc tgccggacgg ctcctggtac gcggcctacg
    21481 ccgacggcga cccggccgca cccaccgacc gcggccggga gaccaacttc gtcgcctacg
    21541 tcgccgtggg cgtctggcac cactacctct ccaccggcga cgagaccttc ctcgaccgga
    21601 tgtggcccac cgtctacgcc gccgtcgagt tcgtcctcgc cctccagcag cccggcgggc
    21661 agatcggctg gaaacgcgag gccccggagc gcgacggcga cgcgggggcg gccgtcaccg
    21721 acgcgctgct caccggcagc tcctccatcc accaggcgct gcgctgcgcc ctggccatcg
    21781 ccgagcagcg cgaggacccg cagcccgact gggagctggc gaccggactg ctcgcccacg
    21841 ccatccggca ccacccggag cgcttcctgg acaagtcccg ctactccatg gactggtatt
    21901 acccgatcct cggcggggcg ctgaccggca ccgcggccaa ggagcgcatc gaggagggct
    21961 gggacgactt cgtggtcccc ggactcggcg tccgctgcgt gctgccgaac ccgtgggtca
    22021 ccggcggcga gagcgccgaa ctggcgctcg ccctctgggc catgggggag tcggaccgcg
    22081 ccgtggacat cctccgctgg atcggccgtc tccgggacga cgagggcatg tactggacgg
    22141 gctatgtcta cgaggacgcc gccttctggc cggaggagca gacgacctgg acggccggtt
    22201 cggtgctgct ggccgtggcc gccctcgggg gcgacgaggc cacgacggcc gtcttcggcg
    22261 gcgaacggct gcccgcgggg ctggacccgg actgctgctg aggcgggacg gctgtggcgg
    22321 cggaggagcc gccggtccgg catccggccg gggaccccgg tcgcggcggg gtccccggcc
    22381 ggacggctgc gagcccggcc gggggtcagg ccccgcgcgg catacgggcc gccagggcgt
    22441 gcccgatggc gaggtacacc accgccggca ggccgtagtt cagcaccacg cgcagccagt
    22501 cgagttccat cgtgaagagg tcgcgggacc atccggccag ccagtgggcc gcgttctgga
    22561 cgaagttcac caggtcgttc gcccggttcg cgtcgagcag atacatgatg atccacagga
    22621 ccaggattcc cgcggccaca tcagccacca gccggatcgc cgcggccgcg gtactgccgc
    22681 ctgaacgtcg gtaagggctc atgcaccccc gtcttgcccg gttcatgcca cgg
//
