LOCUS       NZ_CP023202            23608 bp    DNA     linear   CON 21-MAR-2024
DEFINITION  Streptomyces xinghaiensis S187 chromosome, complete genome.
ACCESSION   NZ_CP023202
VERSION     NZ_CP023202.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces xinghaiensis S187
  ORGANISM  Streptomyces xinghaiensis S187
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7137891)
  AUTHORS   Zhao,X. and Yang,T.
  TITLE     Draft genome sequence of the marine sediment-derived actinomycete
            Streptomyces xinghaiensis NRRL B24674T
  JOURNAL   J Bacteriol 193 (19), 5543 (2011)
   PUBMED   21914869
REFERENCE   2  (bases 1 to 7137891)
  AUTHORS   Chen,L., Zhao,X. and Lin,S.
  TITLE     Genome mining of a marine derived strain Streptomyces xinghaiensis
            reveals biosynthetic ability of xiamycin analogues
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7137891)
  AUTHORS   Chen,L., Zhao,X. and Lin,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-SEP-2017) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2nd, Dalian, Liaoning
            116023, China
REFERENCE   4  (bases 1 to 7137891)
  AUTHORS   Zhao,X., Yang,T. and Chen,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JUN-2011) School of Life Science and Biotechnology,
            Dalian University of Technology, Linggong Road 2, Dalian, Liaoning
            116024, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2017
            Assembly Method                   :: Canu v. 1.4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly :: Streptomyces xinghaiensis S187 genome
            sequencing
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000220705.2-RS_2024_03_21
            Annotation Date                   :: 03/21/2024 05:53:09
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,157
            CDSs (total)                      :: 6,072
            Genes (coding)                    :: 5,922
            CDSs (with protein)               :: 5,922
            Genes (RNA)                       :: 85
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 36 of 150
            Pseudo Genes (incomplete)         :: 134 of 150
            Pseudo Genes (internal stop)      :: 6 of 150
            Pseudo Genes (multiple problems)  :: 26 of 150
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:47:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 906323
            Orig. end                         :: 929931
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023202.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Shanghai Jiaotong
            University, School of Life Science and Biotechnology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23608
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="2dos"
                     /region_number="6"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /tool="antismash"
     cand_cluster    1..23608
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23608
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13608](-)"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13608)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     gene            complement(428..1489)
                     /locus_tag="SXIN_RS03860"
     CDS             complement(428..1489)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SXIN_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_019710662.1"
                     /transl_table=11
                     /translation="MAEPPAGPALFEIYDEGFDSPSWGGVETALWHLVRSLREAGVAAD
                     FYRASEGADLDVLAARMERDRVDAVFPLVESELFEGAQSKRLPELHARTVRIWHDVSRL
                     SEDLSAPPPCPVHAVAPAVPGAPGAAGCPAQDTHPDGPMHEVFLLDLPWTRCFPDRSVI
                     PWAADHVPAQNLHDPSGPVVLQLGKIDTADAERCLRRLAGAGVPLRVMFATWSRRGREA
                     RELVRAHQGAGRQIEVLDAYDIRTDWDRVFGGAALFLLPSVFHETFNFAAAEAVQLGVP
                     VATLGEGGNLPRFASLRAQTLDALLDRVVAGAGRTLAAKPRLTTGWRDVAARYAEIIRS
                     RRVQTGREEQHDG"
     gene            complement(1482..1730)
                     /locus_tag="SXIN_RS03865"
     CDS             complement(1482..1730)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040007.3"
                     /locus_tag="SXIN_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6137 domain-containing protein"
                     /protein_id="WP_019710663.1"
                     /transl_table=11
                     /translation="MTRMLVLKCLSDETGDDAGDIVAQGFVDVDDREFLNIVNRLEGYF
                     DCTLSLRSRPGRRLVVQDLVELVTEATGHGPREVRHG"
     gene            complement(1727..2398)
                     /locus_tag="SXIN_RS03870"
     CDS             complement(1727..2398)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012521.4"
                     /locus_tag="SXIN_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_019710664.1"
                     /transl_table=11
                     /translation="MTAAQRFVLVRHAEASLNVLRDDDVLPGFDPHAGLTPLGERQARA
                     LADHLPGDPAVGPPDRGPGAAVRVYSSPQRRAARTAEVLGAALGVPVVADARLAELRAP
                     EAFPRPLVVREWDAVLEDRLRHPAAEVRGVESWVAQRRRIGEFLAACCPAGGDGARWVL
                     VSHSETMQALLFELLGLDDALLRRTRFKISNTGVFIVDRTEDGCASLVVANSKAHLART
                     A"
     gene            complement(2395..3294)
                     /locus_tag="SXIN_RS03875"
     CDS             complement(2395..3294)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="SXIN_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_019710665.1"
                     /transl_table=11
                     /translation="MASDIVWPPPVRRVRTYRNIVVDGACNIRCTYCEVKKTKVDQPAT
                     IRSLDRIFAEYEPDTVLFRVESDGEITLYPKIVDHLQKRAAEGYRIEVLSNGTKLPRAL
                     EGRPDLLWVFSVDGHTEAMNSKRGLKQGQIDRILDAAVELKAELQTVYWGQPVEEVNAY
                     IDLLRSRNYQGLLHFMPLLAFKGQPLTVNLRYQDLNPADFLAPPEYFRRWNHIYETGKR
                     DAVCDQITNGYNYQVSGEEIRMVKCDCYSVPKHLVHGFGPIREFDDWPCGTCIANQEFN
                     NSRERMRVPQGGVPLPVV"
     gene            complement(3345..4970)
                     /locus_tag="SXIN_RS03880"
     CDS             complement(3345..4970)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.4"
                     /locus_tag="SXIN_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GMC family oxidoreductase"
                     /protein_id="WP_019710666.1"
                     /transl_table=11
                     /translation="MKRLRGPLPSDTAHAWHPEPLGPVHRDGWDPRDDGRIWDVVVIGS
                     GASGSVAADRLVRQGLDVLMVEEGFRLSPGLGNPELDDMCRTALARDGNGGWTDEGWPW
                     TTSNLGGGTVFYGGASWRYRPFDFDPSELIDAGDLDVRWPYGLAELAPYYDVLERRLGV
                     CGGEEGGGSRGPAHPPTAAAEVLYEAGTELGYDPFPTPLAINRHAHDGRSACARDTLCV
                     SHQCPTGAKGDAVAVFLAPLAGHPGFALRTGLRALRLDQERSDAVTSVTCLDRLTRTAH
                     RIRARSFVVACNAIQTAALLLRSHGGHAPGGVGNHSGLVGRGLTMKLSEYVSGFVEVSA
                     ETTLADWRTHSGPFSTIAFLDHYVDPGCPTGVGGMIYESKNDMPERIRHDVLELRVETI
                     LADHPNLDNRVRLSRRVDEDGVPAVVIDYTTDPRDLRRLAYMTGKCERLLRQAGATAIQ
                     HEESGFAQGSCHLHGTCRAGDDPATSVVDGWGRVHSAPNVYVVDGSFMPYPGGLNPTLT
                     IQAHALRSAKAVAGDLVSRHAAHV"
     gene            complement(5048..6832)
                     /locus_tag="SXIN_RS03885"
     CDS             complement(5048..6832)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958279.1"
                     /locus_tag="SXIN_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_019710667.1"
                     /transl_table=11
                     /translation="MKGHEEAPSRAQRDALLRMLLWPKRRRLAAATALALVENVCGLVP
                     PLLIAAAIDRGVPEAADGRWTPLIGFTAAALAAGLTTATLKWCFLRYSGGIAQDLLFEL
                     RHRAFTHVMGQPLAFHESYPSGRVIARLSSDVESVEEMLEMGLDGLFSALFSMVGILAV
                     MLWMDQPMAAVVIVLFIPLYVLTQWFRNRSRRAYRSTRTAVEGVVQHTVEAFNGIRAVQ
                     AFRREEANAARLRRLDARYTVARADAGWVSATFSGGVKLIGNLSLAGLLTLGVFRMDQG
                     QLAIGTLTAFLLYVHRLYDPIDELASFANAFSAASAGLEKIGALFVPHPAVAEPKRPVA
                     LPADPPGGRGAVRFEGVHFRYGDEGRRVLSGVDLVLEPGRTVALVGTTGAGKSTIAKLM
                     ARLYDPAAGRVRLDGVDLRELADAELRGAVSMITQEAFLFSGSVADNIALGRPDASRAE
                     IRAAAESVGAHGFISALPGGYDTDVHKRGSGLSAGQRQLIAMARVMLTSPRVLILDEAT
                     SSMDTPSERAVHEALTRVLAGRTAVIIAHRLSTLAIADRVLVIENGAVVEDGSPAQLLN
                     AGGRFAGMQRGWLAVTTA"
     gene            complement(6829..8664)
                     /locus_tag="SXIN_RS03890"
     CDS             complement(6829..8664)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565907.1"
                     /locus_tag="SXIN_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_095757909.1"
                     /transl_table=11
                     /translation="MTSLRRCAPYLRPHRWLMAGACVAAFGSMLAGLAMPLVLQRLVDG
                     PVVERDLAALPWFIGGFALLGVVEAVLLGARRLLVVRPATRLETAMRADVSAHIQRLPL
                     SFHSRWQSGQLRSRTVSDVMEIGRFAAFSAIYLMVNVAALAVGLGVLAWLAPVLALIVF
                     LAYVPMVVATTVFEQRFRVVARSAQEVGGDLSTTVEESVLGVRVLKVFGRGPEAVRQFT
                     GRARRLRDLELRKLSYTAALWWIITALPDLAIVAMIGYGGHSVATGALTLGTLMAAVTV
                     ATYLRWPADTLGWLTADASTAATAADRYWQVRDEPVTVTDPERPRPLPSPVRGEIRLEG
                     VHYAHPGGRTATLRGVDLTVRAGTTVAVAGATGSGKSTLLSLLSRLDDPTSGRITLDGV
                     DLRDLALADLRSVVSGAFDDPVLFSGTVRANVTLGLPETGDAAAGEDGDAAVWEALRTV
                     RADAFVSALPDKLSTVIGEEGLGLSGGQRQRLALARAILRRPTVLVLDDALSALDVRTE
                     REVETALRGVLCRVTTFVAAHRPGTLRLADQVVFLSGGRVAATGTHDELMAREPEYRLL
                     VAPSLPTVIARPEDDSDDILDDITADGMAGRGRTR"
     misc_feature    complement(8320..8322)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8661..9929)
                     /locus_tag="SXIN_RS03895"
     CDS             complement(8661..9929)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /locus_tag="SXIN_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_019710669.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.2e-26,
                     bitscore: 91.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFFHHDCVTAWPAEFDAVGGMQVQILRLSRELADRGVE
                     QLVMTVGFPGLPRERVDRPGLTVRVTRAPLPRLRSELTGLVGLNQAWLAAVPAACRPLR
                     RTWQPDLVHVHADGQLWALLAGPLVSRILGAPYVITLHCSRLAVYEPMSRFDRLQHRLV
                     TAAERYALRHARRVSVLTARTADTVARLLPLDRALVDVLPDSVGDVRPVPRRRAEEYVR
                     SLGVPAGVPVVGWVGRIAHEKGWRDFVAMAGRWDATVSAAPGAVFLVVGDGPQRERMRE
                     AVGAARLANRFVFTGFLPHDAVPSVMTALDVLVMPSAHEELGGSALEAMVCGTPVAGYA
                     VGGLPDTVGSVTPGLLVPRGDVAALARVAGEAVTEAERHRKTVASAVPDLLSRYGADTV
                     ERALAHYRRALGRTSGGGAGCTP"
     gene            complement(10001..11176)
                     /locus_tag="SXIN_RS03900"
     CDS             complement(10001..11176)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013887.4"
                     /locus_tag="SXIN_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-deoxy-scyllo-inosose synthase"
                     /protein_id="WP_019710670.1"
                     /sec_met_domain="DOIS (E-value: 2.8e-170, bitscore: 564.4,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 5.8e-70, bitscore:
                     233.9, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVTPIAMEDASFPYRLGTECAEDVITCLAALGASSYLVVADTTV
                     AELYGLDLATRIGKEAGPAHLLTHEAGEVHKVLATVSALAEQALERGADRRSLVVALGG
                     GVTGNIAGLMASLLFRGIRLVHVPTTVVAMLDSVLSLKQAVNATFGKNLVGTFYQPVEV
                     LADTAFLRTLPPREIRSGMGEVVKNALAIRPAMLDRLAGALRVDARYDDETLRWIIAES
                     LAAKADVTRDDKHERRSGLVLEYGHTAGHAIEHASRGEVAHGAGVAVGMTVAAEVSRRL
                     GHADAGLVPLHRELVAAAGVEPAIPAHVDTSLIRNWLAYDNKRGYLDSPPGHTPMVLLS
                     APGDVLHTGTLPLVPVPLALLDEVVDEAASRGGAAEPAAAYAGSPPAGPLP"
     gene            complement(11232..12506)
                     /locus_tag="SXIN_RS03905"
     CDS             complement(11232..12506)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970228.1"
                     /locus_tag="SXIN_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_039823026.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.7e-104,
                     bitscore: 347.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSRLAVNGGDALRTRPWPAWPQPAPGVAGAMADVLGSGRWSISG
                     PYRGTDSYERRFARAFAAYNGVPHCVPAASGTAGLMLALEACEVGAGDEVIVPGLSWVA
                     SGSTILGVNAVPVFCDVEADTLCLSPDAVEAAITERTRAIVVVHLYSALADMDPLLRIA
                     ERHGLPLIEDCAQAHGATYRGVKVGALSTAGTFSMQHSKVLTSGEGGAVVTRDAHFARR
                     VEHLRADGRCLSATLPSPGAMELVETGELMGSNRCLSEFQAAILTEQLTILDEQNETRR
                     SNAARLDGLLGGLGLRPQTTSAGTTSRTYYTYAVRLPDGVLEDVPVTEVTDALTAELGF
                     PVLPCYAPIPANKLYAPHTRRRYTLGLAHEERIDPKRFALPVCEGAARRTVTLHHAALL
                     GGEEDMGDIAAAFAKVLRHGAELVH"
     misc_feature    complement(12468..12470)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12586..13608)
                     /locus_tag="SXIN_RS03910"
     CDS             complement(12586..13608)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031129625.1"
                     /locus_tag="SXIN_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alcohol dehydrogenase catalytic domain-containing
                     protein"
                     /protein_id="WP_019710672.1"
                     /sec_met_domain="ADSI-DH (E-value: 3.1e-167, bitscore:
                     554.0, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 4.3e-25, bitscore: 86.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-15, bitscore:
                     56.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVFEAPERAVLTHRDIPDPAPGEALVRIAYNSVCGSDLSFYK
                     GVWHGFTYPVVPGHEWSGTVVDVNGARGTNLVGSNVVGDLTCSCGVCAHCVAGTPTLCE
                     DLGELGFTRDGACAEYMTIPVANLRRLPDTLPLRAACQVEPLAVALNAVDRLGVAGGEK
                     VAVMGAGGIGLLLVQAVRLRGGTVTAVAEPVPERRAAALAMGVPAAVSGAPGALVELTG
                     ANPDAVPDVVLEGSGYPTAVQEAVEAVRPGGRVGLVGYRIEESAVMAPHHIVLKMLTVR
                     ASMGPGTCFEEAIDVLASGAVDVDGLLSHEFPLDDHAKALDVALRRSDGNTRSYFNLHA
                     "
     gene            13826..14335
                     /locus_tag="SXIN_RS03915"
     CDS             13826..14335
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958273.1"
                     /locus_tag="SXIN_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_192883546.1"
                     /transl_table=11
                     /translation="MAGSGQVPEPPERPLVREFGQRLNELIAAMYPDQRKRPGYARLAK
                     EIRETTGGAISGTYLWELATGKKRNVTLEQLDVLAEFFGVPPEYFLNEETAERVNSQLK
                     LATALRDARVRNLALRADGLSAESLDALLIMVNEARRVQNLAAFNDQDHMGAPDGGPTG
                     TSGSTT"
     misc_feature    14777..14793
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.46"
                     /tool="antismash"
     gene            14913..15431
                     /locus_tag="SXIN_RS03920"
     CDS             14913..15431
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958272.1"
                     /locus_tag="SXIN_RS03920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_039823029.1"
                     /transl_table=11
                     /translation="MPYRIARLRRRCRPLLDQLALPRPFSIEPLCAHLSAHRRRPLHLH
                     PLPPQAAAAGACGLWVATDTDDHIFYEQRTARSHQEHIVLHEIGHMLFNHHAVTDTAGS
                     PVGLLGDLSPRLVRRILARANYSTRQEQEAEMLATLIRTGETGPVRCPPSDTYGKLHAA
                     LGVSTDHEL"
     gene            15421..>16530
                     /locus_tag="SXIN_RS32870"
                     /pseudo=""
     CDS             15421..>16530
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="SXIN_RS32870"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MAB_1171c family putative transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSCDLPGAWGTLETFSVGFLWAAVLLRARPAVRNPHQRGLWLAVA
                     SAAVAMTLHLGPVSAYAAELTGSPRAVALAKNQVGVMSAAAVLHFAVYATRGRRHTGTV
                     LVAMITVMAALLALAGLGAAPAPGHGPPFTLARPSSAAYWLLLITAHVVACAACVRVCW
                     TYGRRGPHASVNLGLTLFGWGTALAGLFWLTHYFLLAAGSRPGVPLCLIISLHAVLRAA
                     ALLVPTVMQLRHTADHARTIWRIWPLWRDLVDAVPHVALSPTRSRLLVLLQPQLSWRLI
                     AYRKVIEVRDVILVLSHYTDPGVSRSARAHVVRCGIPADHADAYVTACVLSRARAAKLA
                     GAGPDPAADMPTSSQEAGDLAAETAFLLLL"
     misc_feature    15433..15435
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16633..16647)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            16696..17490
                     /locus_tag="SXIN_RS03925"
     CDS             16696..17490
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="resistance (resist) APH3"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836270.1"
                     /locus_tag="SXIN_RS03925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="APH(3')-V family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="WP_095757910.1"
                     /sec_met_domain="APH (E-value: 6.4e-33, bitscore: 113.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSTLRRTYPHYAWRLVNEGDSGAFVYHLTGHRPELYAKIAPRTP
                     ENPAFDLVGEADRLEWLAHHGIPVPRIVERGADDTTVWLVTEAVPGAAASEEWPEHQRT
                     AVVEAIAELARTLHELPVDDCPFDRRLDVAVAEARHNVREGLVDLDDLQDEHAGWTGDQ
                     LLAELDRARPEKEDLVVCHGDLCPNNVLLDPETCQVTGVIDVGRLGVADRHADLALAAR
                     ELEIDEDPWFGPAYAERFLEQYGAHRVDKDKMAFYQLLDEFF"
     misc_feature    16708..16710
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(<17706..17963)
                     /locus_tag="SXIN_RS31695"
                     /pseudo=""
     CDS             complement(<17706..17963)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1164: transposase
                     IS3/IS911 family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611781.1"
                     /locus_tag="SXIN_RS31695"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPAPHPEEFRDDVVRVARNHEKGATLAQTARDFGVREMTLSKWLR
                     RAAVEDGEKPGVTRSESAENRELKKRVRLLEQENEVLRRAA"
     misc_feature    18076..18086
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            18120..19384
                     /locus_tag="SXIN_RS03935"
                     /pseudo=""
     CDS             18120..19384
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543022.1"
                     /locus_tag="SXIN_RS03935"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNSAYATVDHVFTVPLDHAAPHGPTIQIFAREVTEVGKVGDQLPW
                     LLYLQGGPGGKSPRPSAGSPGWLPRLSKPTGSSSSTSAALGVPPPLPPGLPLASPHQPG
                     WPSIWATSAPTRSSRTPS"
     misc_feature    18390..18392
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19515..20111)
                     /locus_tag="SXIN_RS03940"
     CDS             complement(19515..20111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538890.1"
                     /locus_tag="SXIN_RS03940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin transporter BioY"
                     /protein_id="WP_019710678.1"
                     /transl_table=11
                     /translation="MSSVAYAIPRRGALADSVWARSRVRDAVLVLGAAGLTALAAQISV
                     PVPGSPVPVTLQTFAVLVTAAALGATRGALGQLLYLAIGAAGLPVFSGATGGLSTVLGA
                     TGGYLLGFVVAGYLVGALAQRGADRRVAGTLLAYLAGSAAIYAVGVPVLAAVTHQSLGW
                     AVLHGLVPFLVGDVLKAVAASAALPAAWRVMGRRR"
     gene            complement(20172..21143)
                     /locus_tag="SXIN_RS03945"
     CDS             complement(20172..21143)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076122.1"
                     /locus_tag="SXIN_RS03945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="WP_019710679.1"
                     /transl_table=11
                     /translation="MAIEILNPGLASSIQDRGRPGYYEVGIPPSGAVDLYSALAANLLV
                     GNDDGAALIEAAYMGPELRFTAPAVVAVTGAGMPVKVNGRSAPQWESFDIGAGDVLSFG
                     FLEHGARIYIAVSGGIDVPLVLGSRSTYALGAFGGFDGRTLKAGDVLATGTDTGSGRPG
                     RAVPEHLRPELSRELELRVMLGLYDYRLTPAGLTALLDTTWTLTPVADRVGFRYSGGTL
                     EWKERVQPFGAGSDPSNIVDAGYPLGSIQVPGGVEPIILHRDAVSGGGYAMVATVISAD
                     LDAVGQSAPGSRTRFCPVSMEQALQARAETAARVRQLRTALS"
     gene            complement(21133..22020)
                     /locus_tag="SXIN_RS03950"
     CDS             complement(21133..22020)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076120.1"
                     /locus_tag="SXIN_RS03950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="WP_019710680.1"
                     /transl_table=11
                     /translation="MSPLNSRYSWGGDEHLVVQLDEAMSLEVNFEAMAMARLLQSQKLP
                     GVIDVCPANASLMVRFDPDVIAPAALEGAVRQVEREVGDAPSLTLQTRIVEVPVWYDDP
                     FTNETGARFRDRHQRPEGNDLEFAAIENGLPSVQAFIDRHSGSPWITSMVGFVAGLPFL
                     FQMVPQERQLEVPKYLRPRTDTPALTVGYGGCFSCIYSVRGAGGYQMFGVTPVPIFDPA
                     RKLPDFADFMVFFRPGDIVKFRAIDGDEYERVRQDVEAGAFRYRQSPVSFSLHDFLAGP
                     DAYNATLLEALHGH"
     gene            complement(22017..23393)
                     /locus_tag="SXIN_RS03955"
     CDS             complement(22017..23393)
                     /EC_number="6.4.1.2"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076118.1"
                     /locus_tag="SXIN_RS03955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_019710681.1"
                     /sec_met_domain="ATP-grasp (E-value: 3.2e-07, bitscore:
                     28.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.4e-10,
                     bitscore: 38.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLLVANRGEIAVRVIRAARELDVRTVAVCSETDTEALHVRMAD
                     EHVVIGPAPAARSYLDADAVVAAAVRLRADAVHPGYGFLSERAAFAQQVIDAGMTFVGP
                     SPEAIHLMGDKALARSTAARAGVPTVPGSDGPLTDVDSALETAGHVGYPIAVKAAAGGG
                     GRGIRVVRSPAELREALPLAQAEAKAAFGNGEVYLERFVHNARHIEVQVFGDGERFVHL
                     GERDCSLQRRRQKVVEEACAPNLPAQVRQDMTNAAVSLAAAVSYSGAGTVEFLYDSARQ
                     EFFFIEMNTRIQVEHPVTEMVTGRDLVREQLTVAAGAPLSFTQQQVEPRGHALEFRLNA
                     EDPGAGFMPSPGTITVMRMPGGPFVRIDSGCEQGSQVSPFYDSLIAKLIVWGDTREAAL
                     ARARRALDEIEVRGVATTAPFLRSLVDLPEFAEANYHTTFLESWMAGHASDRDAAGRAA
                     "
ORIGIN
        1 caccgtgtcg gcgcccgacg cgcgcaccgc ctgcgtgatc gcctcctcca cggcaccgcg
       61 cagttcgtcc gcctcggccg gcgacgacac ctctgcctcg tcgtcgtagc cgcgcagact
      121 ggcgtcgtcg aaaccgagcg gacggtagtc cgccagcccg cgcagccggc agtagcccag
      181 ctcctcctcc cggcgccggg cgctgatcac ccgcaccccg gcgcgccgca gccgcctgga
      241 cagcgcccag ccggagcggg tgaacaccgt gagcagcgtc gcatgcgcgg ggcgtcccac
      301 cgcggccagc agcccaccgc acgagtacgc cacgtcgtcc gggtgcggtg acaccagcag
      361 cgtccgcccc tcacgcagcc gcgcggacag ggcccggtct gttccgtccg tcgccttccg
      421 tgtgggttca cccatcgtgc tgttcctccc gtcccgtctg cacccgccgg ctccggatga
      481 tctcggcgta ccgggcggcc acgtcacgcc agcccgtcgt caggcgcggc ttcgccgcca
      541 gggtgcggcc cgcacccgca acgacccggt ccagcagagc gtccagcgtc tgggcgcgca
      601 gtgacgcgaa ccggggcaga ttgccacctt cgccgagggt cgccaccggc acacccagtt
      661 gcacggcctc cgccgccgcg aagttgaagg tctcgtggaa caccgacggc agcaggaaca
      721 gcgccgcacc gccgaagacc cgatcccagt cggtacgaat gtcataggcg tccagcacct
      781 cgatctgccg gcccgccccc tggtgcgccc gtaccagctc acgcgcctcc cggccccggc
      841 gcgaccaggt ggcgaacatg acgcgcagcg gcactccggc cccggccagc cggcgcagac
      901 agcgttccgc gtcagccgtg tcgatcttgc cgagttggag caccaccgga ccggacgggt
      961 cgtgcaggtt ctgcgccggg acgtggtctg cggcccacgg gatcaccgac cggtccggga
     1021 agcagcgtgt ccagggcagg tccagcagga acacctcgtg catcggccca tcggggtgcg
     1081 tgtcctgcgc agggcacccc gccgccccgg gcgcgcccgg cacggcggga gcgaccgcgt
     1141 gtaccgggca cggcggcggc gccgacaggt cctccgacag cctgctgacg tcgtgccaga
     1201 tccgtacggt tctggcgtgc agttccggca accgcttcga ctgcgccccc tcgaacagct
     1261 cgctctccac gagcgggaac accgcatcca cgcgatcccg ctccatccgc gccgcgagca
     1321 cgtccaggtc ggcgccttcc gaagcacggt agaagtccgc cgcgaccccc gcctcgcgca
     1381 gcgaccgcac caggtgccac agggcggtct ccacgccacc ccacgacggc gagtcgaagc
     1441 cctcgtcgta gatctcgaac agggccggtc cggcgggcgg ctcagccatg gcgcacctcc
     1501 cgcgggccgt gccccgtggc ctcggtgacc agctccacca ggtcctgcac cacgagtcgc
     1561 cggcccggcc gtgacctcag cgacagcgtg cagtcgaagt agccctccag ccggttgacg
     1621 atgttgagga actcgcggtc gtccacgtcc acgaacccct gggcgacgat gtccccggcg
     1681 tcgtcgccgg tctcgtcgct gaggcacttc aggacgagca tgcgggtcat gccgtcctgg
     1741 ccaggtgcgc cttgctgttc gccaccacca gggaagcgca tccgtcctcc gttctgtcca
     1801 cgatgaacac accggtgttg ctgatcttga agcgggtgcg gcgcagcagc gcgtcgtcaa
     1861 ggcccagcag ttcgaagagg agggcctgca tcgtctcgga gtgcgacacg agcacccatc
     1921 gggcgccatc cccgcccgcg gggcagcacg cggccaggaa ctccccgatg cggcgcctct
     1981 gcgccaccca gctctccacg ccccgtactt cggccgccgg atgccgcagc cggtcttcca
     2041 gcactgcgtc ccactcgcgg accacgaggg gccgcgggaa ggcctccggc gcccgcagct
     2101 ccgccagccg ggcgtccgcc accactggca cgcccaaggc ggcgcccagt acctccgcgg
     2161 tgcgggccgc ccgccgctgc gggctggagt acacccgtac ggcggcgccc ggcccacggt
     2221 ccggtgggcc caccgccggg tccccgggca ggtggtcggc gagggcccgg gcctgccgtt
     2281 cgccgagcgg ggtgagtccg gcgtgtgggt cgaagcccgg caggacgtcg tcgtcccgca
     2341 acacgttcag gctcgcctcg gcgtgccgga ccagcacgaa cctctgggcg gccgtcatac
     2401 gaccggcagc gggacgccgc cctgcgggac acgcatccgc tcacgcgagt tgttgaactc
     2461 ctggttggct atgcaggtgc cgcacggcca gtcgtcgaac tcgcggatcg ggccgaagcc
     2521 gtgcaccaag tgcttgggca ccgagtagca gtcgcacttg accatccgaa tctcttcccc
     2581 ggacacctgg tagttgtagc cgttggtgat ctggtcgcag accgcgtccc gcttgccggt
     2641 ctcgtagatg tgattccagc ggcggaagta ctcgggcgga gccaggaagt ccgccgggtt
     2701 caggtcctgg tagcgcaggt tcacggtcag cggctgtccc ttgaaggcca gcagcggcat
     2761 gaagtgcagc agcccttggt aattcctgga cctgaggaga tcgatgtacg cgttgacctc
     2821 ctccaccggc tgaccccagt acacggtctg gagctccgcc ttcagctcga cggcggcgtc
     2881 caggatgcgg tcgatctgtc cctgtttcag accgcgcttg gagttcatcg cctcggtgtg
     2941 gccgtccacc gagaacaccc acagcaggtc cgggcgtccc tccagggctc ggggcagctt
     3001 cgtgccgttg ctcagcactt cgatgcggta gccctcggcc gcccgcttct gcagatggtc
     3061 gacgatcttc gggtagaggg tgatctcgcc gtcggactcc acccggaaca gcaccgtgtc
     3121 cggctcgtac tcggcgaaga tccggtccag tgaacggatg gtggccggct ggtccacctt
     3181 ggtcttcttg acctcgcagt aggtgcatcg gatgttgcag gcgccgtcga cgacgatatt
     3241 gcggtaggtg cgcacccggc gcacgggcgg cggccagacg atgtcggatg ccatggtgtg
     3301 actcctcgct cggggtgggg aagaaccggc cgcggtgcgg tggctcatac atgcgcggcg
     3361 tgccgggaca ccaggtcgcc ggccaccgcc ttggcgctgc gcagcgcgtg cgcctggatg
     3421 gtgagggtgg gattgaggcc gcccgggtac ggcatgaagc tgccgtcgac gacgtacacg
     3481 ttgggcgccg agtggacgcg gccccagccg tccaccaccg acgtggccgg gtcgtcgccg
     3541 gcccggcagg tgccgtgcag atgacagctg ccctgcgcga acccgctctc ctcgtgctgg
     3601 atagcggtcg cgcccgcctg ccgcagcagc cgttcgcact tgccggtcat gtaggcgagg
     3661 cggcgcaggt cgcgcgggtc ggtggtgtag tcgatgacga cggccggcac gccgtcctcg
     3721 tcgacgcggc gggacaaccg gacccggttg tccaggttcg ggtggtcggc aaggatcgtc
     3781 tcgacgcgca gctccagcac gtcatgccgg atgcgctcgg gcatgtcgtt cttcgactcg
     3841 tagatcatgc cgcccacgcc tgtggggcag ccggggtcca cgtagtggtc gaggaacgcg
     3901 atcgtggaga acgggcccga gtgtgtgcgc cagtcggcga gcgtcgtctc cgccgacacc
     3961 tcgacgaagc cgctgacgta ctcgctcagc ttcatcgtca gcccgcggcc cacgaggccc
     4021 gagtggttgc ccacgccgcc cggtgcgtgc ccaccgtggg accgcagcag cagcgcggcc
     4081 gtctggatcg cgttgcacgc gacgacgaac gacctggccc ggatccggtg cgcggtgcgg
     4141 gtcagccggt ccaggcaggt gaccgaggtg accgcgtccg acctctcctg gtccaggcgc
     4201 agtgcccgca gcccagtccg cagcgcgaag ccggggtgtc cggcgagcgg ggcgaggaag
     4261 acggcgacgg cgtccccctt ggcgcccgtc gggcactggt ggctcacgca cagcgtgtcc
     4321 cgcgcgcacg ccgaacgccc gtcgtgagca tggcggttga tggccagtgg tgtggggaac
     4381 gggtcgtagc cgagttcggt gcccgcctca tacagaacct cggccgcggc tgttggcggg
     4441 tgcgccgggc cgcggctgcc tcccccctcc tcgccgccgc acaccccgag ccgccgctcc
     4501 agcacgtcgt agtacggggc gagttcggcg agcccgtacg gccagcgcac atcgaggtcg
     4561 ccggcgtcga tcagctcgct cggatcgaag tcgaacggcc ggtagcgcca cgaggcgccg
     4621 ccgtagaaga ccgtcccgcc gcccaggttg gatgtcgtcc acggccagcc ctcgtcggtc
     4681 cagccgccgt tgccgtcacg ggccagggcg gtgcggcaca tgtcgtccag ctccgggttg
     4741 ccgaggccgg gagagagccg gaaaccctcc tcgaccatca ggacgtccag cccttgccgg
     4801 acgagccggt ctgcggccac cgaaccactg gcaccgctgc cgatcacgac gacgtcccag
     4861 atccggccgt cgtcccgggg gtcccacccg tcgcggtgca cgggccccag cggctcgggg
     4921 tgccatgcgt gcgcggtgtc cgagggcagg gggccccgaa ggcgcttcat cgtgtgcctt
     4981 tcgtcgaagg gtgattacgg ggaggcgggg agagccaccg ggcagaagct cccggggcat
     5041 ggcgacgtca cgctgtcgtg acggccagcc agccccgctg catgccggcg aaccgtccgc
     5101 ccgcattcag cagttgcgcc ggactgccgt cctcgaccac cgccccgttc tcgatgacca
     5161 ggacgcgatc ggcgatggcg agcgtggaca accggtgcgc gatgatcacc gcggtgcggc
     5221 ccgcgaggac ccgggtcagc gcttcgtgca cggcccgctc cgacggggtg tccatgctgg
     5281 acgtcgcctc gtcgagaatc agcacgcgcg gcgaggtcag catcacccgc gccatggcga
     5341 tcaactgccg ctggccggcc gacaggcccg aaccccgctt gtgcacgtcc gtgtcgtagc
     5401 caccgggcag cgcgctgatg aatccgtgcg cgcccaccga ctcagcggcc gcccggatct
     5461 cggctcgtga agcgtccggc cggcccagcg cgatgttgtc cgcgaccgac ccggagaaca
     5521 ggaacgcctc ctgggtgatc atcgagacgg cgccgcgcag ttcggcgtcg gccagctccc
     5581 gcaggtccac cccgtccagc ctgacccggc ccgccgcggg atcgtacagc cgcgccatca
     5641 gcttggcgat cgtggacttg ccggcgccgg tggtgcccac cagggcgacc gtacggcccg
     5701 gttcgagcac caggtcgacg ccggacagca cacggcggcc ctcatcgccg taccggaagt
     5761 ggacgccctc gaacctcacg gcgccccgcc cgcccggcgg gtccgccggc aacgcaaccg
     5821 gacgcttcgg ctcggccacc gccgggtggg gcacgaacag cgcaccgatc ttctccaagc
     5881 ccgccgacgc cgccgaaaag gcgttggcga aactcgccag ctcgtcgatc gggtcgtaca
     5941 gccggtgcac gtacagcagg aacgcggtga gcgtgccgat ggccaactgg ccctggtcca
     6001 tgcggaacac gcccaacgtc agcagcccgg ccaatgacag gttgccgatg agcttcactc
     6061 cgccgctgaa ggtggcgctc acccagccgg cgtccgcccg cgccaccgtg taccgggcgt
     6121 cgagccggcg cagccgggcc gcgttggcct cctcgcggcg gaacgcctgt acggccctga
     6181 tgccgttgaa ggcctccacc gtgtgctgca ctacgccctc gacggccgtc ctggtgctcc
     6241 ggtaggcgcg ccgcgaccgg ttccggaacc actgcgtcag cacgtacagc gggatgaaca
     6301 gcacgatcac gaccgcggcc atcggctggt ccatccacag catcacggcg aggattccga
     6361 ccatcgagaa cagcgcggag aacagcccgt ccaagcccat ctccagcatc tcctcgaccg
     6421 actccacatc actggacagc cgggcgatca cccgccccga gggatacgac tcgtggaacg
     6481 ccagcggctg gcccatcaca tgggtgaagg cccggtgccg cagctcgaac aagaggtcct
     6541 gggcaatgcc gccggagtag cgcagaaagc accacttgag cgtggccgtg gtcagcccgg
     6601 cagccagtgc cgcagccgtg aagccgatca gcggcgtcca ccggccgtcc gctgcctcgg
     6661 gcacaccccg gtcgatggcg gcggcgatca gcagcggcgg gaccagcccg cacacgttct
     6721 ccaccagggc cagcgcggtg gcggccgcca gccggcgccg cttgggccac agcagcatgc
     6781 gcagcagggc gtcccgctgg gcccgggacg gtgcttcctc gtgtcccttc atcgtgtccg
     6841 cccccgtcct gccatgccgt ccgccgtgat gtcgtcgagg atgtcgtcgg agtcgtcctc
     6901 cgggcgcgcg atgaccgtgg gcagcgacgg cgcgaccagc agccggtact ccggctcacg
     6961 agccatcaac tcgtcgtgcg tgcccgtcgc ggcgacccgc ccaccggaga ggaacaccac
     7021 ctggtccgcc aggcgcagag tgcccggtcg gtgcgcggcc acgaacgtgg tgacgcggca
     7081 gagcaccccg cgcagagcgg tctccacctc ccgctcggtc cgtacgtcca gggcggacag
     7141 cgcgtcgtcc agcaccagta ccgtcggcct gcgcaggatg gcccgggcca gcgccagccg
     7201 ctgccgctga ccgcccgaca ggcccaggcc ctcctcaccg atcaccgtgg acagcttgtc
     7261 gggcagagcg gagacgaatg cgtccgcgcg taccgtccgc agcgcttccc acaccgcggc
     7321 atcaccgtcc tcgcccgcag ccgcgtcacc ggtctccggt aggcccagcg tgacgttggc
     7381 ccgcaccgtg ccggagaaca gcaccgggtc gtcgaacgct ccggacacca ccgaccgcag
     7441 gtcggccagg gccagatcgc gcagatccac accgtccagc gtgatgcgcc ccgacgtcgg
     7501 gtcgtccagc cgggacagca gcgacagcag cgtgctcttg ccggagcccg tcgccccggc
     7561 gacggccacc gtggtgcccg cccggaccgt caggtcgacg ccccgcagcg tcgcggtgcg
     7621 gccacccggg tgcgcgtagt gcactccctc caggcggatc tcgccacgca cgggtgacgg
     7681 cagaggccgg gggcgctccg ggtcggtcac cgtcaccggc tcgtcccgca cctgccagta
     7741 ccggtcggcc gccgtggccg ccgtcgacgc gtcggcggtc agccagccca gtgtgtcggc
     7801 cggccagcgc agatacgtgg caactgtcac cgcggccatc agcgtgccca gtgtgagcgc
     7861 gccagtggcg acactgtggc cgccgtatcc gatcatcgcc acgatcgcca ggtccggcag
     7921 cgccgtgatg atccaccaca gggccgccgt gtacgacagc ttccgcagct ccaagtcccg
     7981 cagccgacgc gcccggccgg tgaactggcg caccgcctcc gggccgcgcc cgaacacctt
     8041 cagcacccgc acaccgagca ccgactcctc cacggtcgtg gacaggtctc cgcccacttc
     8101 ctgcgcggag cgtgccacca cccggaaccg ctgctcgaac accgtggtgg ccaccaccat
     8161 cggcacgtac gccaggaaca cgatcagcgc gagcaccggt gccagccacg ccaggacgcc
     8221 cagacccacg gcgagcgccg cgacgttgac catcaggtag atggcagaga aggccgcgaa
     8281 ccggccgatc tccatcacgt ccgagacggt ccgggaccgt aactgaccgg actgccagcg
     8341 ggaatggaac gacaggggca gccgctggat gtgcgccgac acgtcggcgc gcatcgccgt
     8401 ctccagccgg gtcgccgggc gcaccaccag cagccggcgc gcgcccagca ggaccgcttc
     8461 gaccacaccg aggagggcga acccgccgat gaaccacgga agcgcggcga ggtcccgctc
     8521 cacgaccggc ccgtccacca gccgctggag caccagcggc atggccagac ccgcgagcat
     8581 cgacccgaag gcagcgacgc acgcccccgc catcagccag cggtgcgggc gcagataggg
     8641 ggcgcagcgt cgcagcgacg tcatggcgta cacccggcac ctcccccgga ggtccggccg
     8701 agcgcccgtc ggtagtgtgc cagcgcccgc tccacggtgt ccgccccata acggctcagc
     8761 aggtccggca ccgccgaggc caccgtcttg cggtgccgtt ccgcctccgt gaccgcctca
     8821 ccggcgacgc gggccagcgc cgccacgtcg ccgcgcggaa caagcagccc cggagtgacc
     8881 gaaccgaccg tgtcgggcag cccgccgacg gcgtaacccg ccaccggcgt cccgcacacc
     8941 atggcctcca gcgcgctgcc gcccagctcc tcgtgggcgg acggcatgac gagcacgtcc
     9001 agcgccgtca tcacggacgg caccgcgtcg tgcggcagga acccggtgaa cacgaaccgg
     9061 tttgccagcc tcgccgcccc gacggcctcc cgcatccgct cccgctgcgg cccgtcaccc
     9121 accacgagaa acaccgcccc gggcgccgcc gaaaccgtgg cgtcccaccg gcccgccatg
     9181 gcgacgaagt cccgccaccc cttctcgtgc gcgatccggc cgacccagcc gaccaccggc
     9241 acaccggccg gcacgcccag tgaacggaca tactcttccg cccgccgccg cggcacgggc
     9301 cgtacatccc cgaccgagtc gggcagcacg tccaccaggg cacggtcgag cggcagcagc
     9361 cgcgccaccg tgtccgcggt gcgcgcggtg agcaccgaga cccggcgggc gtgccgcagg
     9421 gcgtaccgct cggccgcggt caccagccgg tgctggagcc ggtcgaaccg ggacatcggc
     9481 tcgtacaccg ccagccgtga gcagtgcagc gtgatgacgt acggcgcgcc gagaatccgc
     9541 gacacgagcg gcccggcgag cagcgcccac agctgtccgt ccgcgtggac gtgcacgagg
     9601 tccggctgcc aggtgcggcg cagtggccgg cacgccgccg gcaccgcggc gagccacgcc
     9661 tggttgagcc cgacgaggcc ggtcagctcg gagcgcagtc ggggaagcgg agcgcgggtg
     9721 acgcggaccg tgagccctgg ccggtcgacc cgctcccggg gcagtccggg gaaccccacg
     9781 gtcatgacga gctgctccac gccacggtcg gccagctccc gcgagaggcg gaggatctgc
     9841 acctgcatgc ccccgacggc gtcgaactcc gcgggccagg cggtgacgca gtcgtggtgg
     9901 aagaaggggg tgagccgcag cacacgcacg gggaactcca cggaaaggga gggcggttgg
     9961 cgaaggcgat acgcggtacg gggtggcgcg gttgtgccgg ttacggcagc gggccggccg
    10021 gtggagagcc cgcgtacgcc gctgcgggct cggcggcccc gccgcgcgaa gccgcctcgt
    10081 cgacaacctc gtccagcagg gcgaggggga cgggcacgag cggcagggtc cccgtgtgca
    10141 ggacgtcgcc gggcgccgac aacagcacca tcggggtgtg cccgggcggg ctgtcgaggt
    10201 agccgcgctt gttgtcgtac gccagccagt tcctgatcag tgatgtgtcg acgtgtgccg
    10261 gaatcgcggg ctccaccccg gcggctgcga ccagttcgcg gtgcagaggg acgaggccgg
    10321 cgtcggcgtg ccccagacgg cgggagactt cggcggcgac ggtcatgccg acggcgacgc
    10381 ccgccccatg ggcaacctcg ccgcgggagg cgtgctcgat ggcgtgcccg gcggtgtggc
    10441 cgtactccag aacgaggccg gagcgacgct cgtgcttgtc gtcccgagtg acgtcggcct
    10501 tggcggccag gctctccgcg atgatccagc gcagggtctc gtcgtcgtag cgcgcgtcaa
    10561 cacgcagggc gcccgcgagc cggtcgagca tggccggccg gatggcgagg gcgttcttca
    10621 ccacctcgcc catgccggag cggatctcgc ggggcggcag tgtgcgcagg aaggcggtgt
    10681 cggccaggac ttcgacgggc tggtagaagg tgccgaccag gttcttgccg aaggtggcgt
    10741 tgacggcctg cttcagcgag agcaccgagt cgagcatggc caccaccgtg gtcggcacgt
    10801 ggacgaggcg gattccgcgg aacagcagcg acgccatcag gccggcgatg ttgccggtga
    10861 cgccgccgcc gagtgcgacg acgagggagc gtcggtccgc tccgcgctcc agggcctgct
    10921 ccgcgagcgc ggacacggtg gccagaacct tgtgcacctc gcccgcctcg tgggtgagga
    10981 ggtgggccgg gccggcctcc ttgccgatgc gggtggcgag gtcgaggccg tagagctcgg
    11041 ccaccgtggt gtccgccacc accaggtagc tgctggcgcc gagtgcggcg aggcaggtga
    11101 tgacgtcctc ggcacactcg gtgccgagcc ggtaggggaa tgaggcgtct tccatcgcga
    11161 tgggtgtgac ctgcatgatc cttcggatcc tccggcggtt cgcgggactg ggatgcggtg
    11221 ggttgccgtg gtcaatgcac cagttcggcg ccgtgccgca ggaccttggc gaaggccgcg
    11281 gcgatgtcac ccatgtcttc ttcgccgccg agcagggcgg cgtggtgcag ggtcaccgtc
    11341 cgccgcgcgg cgccctcgca cacgggcagc gcgaacctct tggggtcgat gcgctcctcg
    11401 tgggccagac ccagcgtgta gcgcctgcgg gtgtgcggcg cgtacagctt gttggccggg
    11461 atcggggcat agcagggcag cacggggaag ccgagctcgg cggtgagcgc gtctgtcacc
    11521 tcggtgacgg ggacgtcctc cagcacgccg tcgggcagcc gcaccgcgta ggtgtagtag
    11581 gtacgggagg tggtgccggc ggacgtggtc tgcgggcgca ggcccagccc gccgaggagg
    11641 ccgtcgaggc gggcggcgtt ggagcggcgg gtctcgttct gctcgtcgag gatggtgagc
    11701 tgctcggtga gaatggctgc ctggaattcg gacaggcacc ggttgctccc catcagctcg
    11761 ccggtctcga ccagttccat ggccccgggg ctgggcaggg tggcggacag gcagcggcca
    11821 tcggcccgca ggtgctccac gcgacgggcg aagtgcgcgt cacgggtgac gacggcgccg
    11881 ccctcgccgc tggtgagcac cttgctgtgt tgcatgctga aggttccggc ggtggagagc
    11941 gcaccgacct tgactccccg gtaggtggcg ccgtgcgcct gggcgcagtc ctcgatgagg
    12001 ggcagcccgt ggcgctcggc gatccgcagg agcgggtcca tgtcagcgag ggccgagtag
    12061 aggtggacca cgacgatggc ccgggtgcgt tcggtgatcg cggcctcgac cgcgtcgggt
    12121 gagaggcaga gcgtgtcggc ttcgacgtcg cagaagacgg gaacggcgtt gacaccgaga
    12181 atggtggagc cggacgcgac ccaggacagg ccggggacga tcacctcgtc tccggcgccc
    12241 acctcgcacg cctccagggc cagcatcagg ccggcggtac cgctcgcggc gggcacgcag
    12301 tgcggcacac cgttgtaggc ggcgaacgcc cgggcgaagc gccgctcgta ggagtcggtg
    12361 ccgcggtagg ggccgctgat cgaccaccgg ccggatccga ggacatccgc cattgcgccg
    12421 gcaaccccag gcgcgggttg cggccatgcg ggccaggggc gcgtgcgtaa cgcgtcgccg
    12481 ccgttcactg ccaaccggga aaccatggac cttccttcct gatgtcatgc cgtggatgtg
    12541 cggatgaggt acgggagggg cggccggcgc ggggcacggc gtcgttcagg cgtggaggtt
    12601 gaagtacgag cgggtgttgc cgtccgagcg gcgcagggcc acgtcgaggg ccttggcgtg
    12661 gtcgtcgagc gggaactcgt ggctgagcag gccgtccacg tcgacggcgc cggacgccag
    12721 gacgtcgatg gcctcctcga agcaggtgcc ggggcccatg gacgcccgga cggtgagcat
    12781 cttgagcacg atgtggtgcg gggccatcac ggccgactcc tcgatgcggt agccgaccag
    12841 gccgacgcgt ccgcccgggc ggacggcctc cacggcctcc tgtaccgcag tcgggtatcc
    12901 cgacccttcc aggacgacat cgggcaccgc gtccgggttc gcgccggtca actcgaccag
    12961 ggcccccggg gcgccggaca cggctgcggg gacgcccatg gccagggcgg cggcgcggcg
    13021 ttcgggcacg ggctcggcca ccgcggtgac ggtgccaccg cgcagccgta cggcctggac
    13081 gagcagcagc ccgatgccgc cggcgcccat gacggcgacc ttctcgccgc cggcgacccc
    13141 caaccggtcc accgcattga gcgcgaccgc cagcggctcg acctggcagg cggcgcgcag
    13201 cggaagggtg tccggcagcc gcctgaggtt cgcgacggga atggtcatgt actcggcgca
    13261 ggcaccgtcc cgggtgaacc cgagctcgcc caggtcctcg cagagggtcg gcgtcccggc
    13321 tacgcagtgt gcgcagacgc cgcacgagca ggtcaggtcg ccgaccacgt tgctgccgac
    13381 gaggttggtt ccccgggcgc cgttgacgtc gacgaccgtg ccgctccact cgtgtccggg
    13441 cacgaccggg tacgtgaaac cgtgccagac gcccttgtag aaggagagat cactgccgca
    13501 gacggagttg taggcgatgc ggacgagagc ttcgccgggt gccggatccg gtatgtcgcg
    13561 gtgagtgagg acggcccgct cgggggcctc gaacaccaga gccttcatcg tgccggacct
    13621 ccgtggtcag ggagcgcccg gcggtccccg ggcgagtggc gttcgctaaa gttgatgaag
    13681 cttggcagga tcgtacgctg ggttgatgtc aacttgtcaa cagtggctga tggttgtttg
    13741 atgatcgggt gagcattgtc cgctgaagcg gtcacggaag cgcgccaggt gtccggggga
    13801 gccggaacgg aagggagaga tgcgcatggc gggtagcggg caggtccctg agccgccgga
    13861 gcggccgctg gtgcgggagt tcggccagcg gctcaacgag ttgatcgccg ccatgtaccc
    13921 ggaccagcgc aagcgaccgg gctacgcccg gctggcgaag gagatccgcg agaccaccgg
    13981 cggtgccatc tccgggacct acctgtggga actcgccacg ggcaagaagc gcaacgtcac
    14041 gctcgagcaa ctggacgtgc tggccgagtt cttcggggta ccgcccgagt acttcctcaa
    14101 cgaggagacg gccgaacgcg tcaactcaca gctcaagctg gccacggcgc tgcgcgacgc
    14161 ccgcgtgcgc aacctcgccc tgcgggccga cggcctgtcc gcggagagcc tggacgctct
    14221 gctcatcatg gtcaacgagg cccgcagagt gcagaacctt gcagcgttca acgaccaaga
    14281 ccacatgggc gcaccggacg gcggcccgac cggaacgtcc ggaagcacga cgtagccggg
    14341 gctacggaac aacgggccca gcaacagcag aggctacgga atatggccgc tggcgtcgtc
    14401 tggagagacg tcatgcatgg ggaggctgtc atcatttctc atatcgttca tcgcccaaca
    14461 ggcatcgcaa ggcagcggag aatcgtttcc ttctccggca cggatgtccg cgcggttccc
    14521 cacacggctt ccctctcggg tttccccgcg agttcggcca caggttcctt cacagcggag
    14581 tggtaaccca ccaccggcca cacagccggt tctgaccagg gccgccgcca accgcccgtc
    14641 cgtacagccg cgaccaccac acgggacccg ctccgcgcgc cccggcatgc cgacccgcgc
    14701 cggaagcacc ccggcgcgct cccgtacgac caggtggccc cggccggccg tcatcccgct
    14761 gacgcccgag tcgcgctgcc gcaaaagacg gcaccgtgcg gccatgccgc cgtgccgcga
    14821 tggcgccctg cagcgcgggc gaacccggcg gacggaccgt tcccgccacg cccgtcaacg
    14881 ccgacccagg aaggccaaac ggtacacacc gcatgccgta caggatcgcc aggctgcgcc
    14941 gacgctgtcg accgctgctg gaccaactcg ccctgccccg tccgttctcc atcgagccgc
    15001 tgtgcgccca cctctccgca caccgcaggc gccctctcca cctgcacccg ctgcctcccc
    15061 aggccgccgc ggcaggagcg tgcggactgt gggtggccac cgacaccgac gaccacatct
    15121 tctacgagca gcgcacagcc cggtcccacc aggaacatat cgtgctgcac gagatcggcc
    15181 acatgctctt caaccaccac gccgtcacgg acaccgccgg ctcacccgtg ggcctcctcg
    15241 gcgacctcag ccctcggctc gtccgccgca tcctcgcccg tgccaactac tcaacccgcc
    15301 aggagcagga agccgagatg ctggccaccc tgatccgcac cggcgaaacc gggcctgtcc
    15361 ggtgcccgcc gtccgacacc tacggcaaac tgcacgcggc cctcggagtg agcaccgacc
    15421 atgagctgtg acttaccggg ggcctggggc actctggaga cgttcagcgt cggcttcctc
    15481 tgggccgctg tcctgctccg ggcccgcccc gccgtacgca acccgcacca gcggggactg
    15541 tggctcgccg tggcctcggc cgccgtcgcg atgaccctgc acctggggcc ggtgagcgcg
    15601 tacgccgccg aactcaccgg ctccccgcgg gctgtcgctc tcgccaagaa ccaggtcggc
    15661 gtcatgtccg ctgcggccgt cctgcacttc gccgtgtacg cgacccgcgg tcgccgtcac
    15721 acgggcactg tcctggtcgc catgatcacc gtgatggccg cactcctggc cctcgccggc
    15781 ctgggagccg ccccggcgcc gggccacgga ccgcccttca ccctcgcccg gccatcctct
    15841 gccgcgtact ggcttctcct catcaccgcg cacgtggtgg cctgtgccgc gtgcgtccgg
    15901 gtctgctgga cgtacggccg ccgcggcccc catgcgtccg tcaacctcgg cctgaccctt
    15961 ttcggctggg gcaccgccct cgccggcctc ttctggctca ctcactactt cctgctggct
    16021 gccggctccc gcccgggcgt tcccctctgc ctcatcatca gcctgcacgc ggtgctgcgc
    16081 gccgccgcgc ttctcgtacc caccgtcatg cagctgcgcc ataccgccga ccacgcccgc
    16141 accatctggc ggatctggcc gctgtggcgg gacctggtcg acgccgtgcc gcacgtcgcc
    16201 ctctccccca cccgctcccg cctgctggtc cttctccagc cgcagctctc ctggcggctc
    16261 atcgcctacc ggaaggtcat cgaagtacgc gacgtcattc tcgtcctcag ccactacacc
    16321 gatccgggcg tttcccgcag cgcccgcgcc cacgtggtcc gctgcggcat tcccgccgac
    16381 cacgccgacg cctacgtgac cgcctgcgtg ctgagcaggg cacgcgccgc caaactcgcc
    16441 ggcgcagggc ccgaccccgc ggccgacatg cccaccagca gccaggaagc cggcgacctc
    16501 gccgccgaaa ccgccttcct gctgctcctc acggaggcct atctctcccc ctgcgtaaag
    16561 gacttcggcc cgggggtggc ggccgccgcg gggtaccgcc gcaggagaag accggtgacc
    16621 ctttccccgc cctgtccgaa accgtccggg aaaatgaccc aggagaggaa ggcagtctct
    16681 gccatgattc cgaccatgga cagcacatta cgccggacat atccgcacta cgcatggcgc
    16741 ctcgtgaacg aaggggattc aggtgccttc gtctaccacc tcaccggcca ccggcccgag
    16801 ctctatgcga aaatcgcgcc gcgtaccccg gagaaccccg ccttcgacct cgtcggcgag
    16861 gcagaccgcc tcgaatggct cgcgcaccac ggcatccccg ttccccgtat cgtcgagcgc
    16921 ggcgccgacg acaccaccgt ctggctcgtc accgaagccg tgcccggcgc cgcggcctct
    16981 gaggagtggc ccgaacacca gcggaccgcc gtcgtcgagg cgatcgccga actggcccgc
    17041 accctccacg aactccccgt ggacgactgc cccttcgacc gccgcctcga cgtggcggtc
    17101 gccgaggccc ggcacaacgt ccgggagggc ctggtcgacc tcgacgacct ccaggacgag
    17161 cacgccggct ggaccggcga ccagctcctc gccgaactcg accgcgcccg gcccgagaag
    17221 gaggacctgg tcgtctgcca cggcgacctg tgccccaaca acgtgctgct cgacccagag
    17281 acgtgccagg tgaccggagt gatcgatgtg ggccgcctcg gcgtcgccga ccgccacgcc
    17341 gacctcgccc tcgccgcccg cgagctggag atcgacgagg acccctggtt cggccccgca
    17401 tacgccgagc ggttcctcga gcagtacggc gcccaccgcg tcgacaagga caagatggcc
    17461 ttctaccagc tactcgatga gttcttctga cctgcttctc acctcggtcc ttcgctcgcg
    17521 gggaccgagg tcttgatgat gtggttgatc tccgctcgtg atcttgctgt cgtttgccgg
    17581 agggagtccg aagatcctgg aggtacggcc gtgctgggct ctccggggtc cggaacggga
    17641 aggaacgttc agtgggcacc ctggctggcc agtgattcgc ccgcctctac gagaacagag
    17701 cccagcgcag cccggcgcag gacctcgttc tcctgctcca gcagccgcac ccgcttcttc
    17761 agttcacggt tctccgccga ctccgacctg gtgacaccgg gcttctcgcc gtcttccacg
    17821 gcggcccggc gcagccactt cgacagcgtc atctcacgaa caccgaagtc cctcgcggtc
    17881 tgggcgaggg tcgcaccctt ctcatggttc cgggccaccc gcacgacgtc atcacggaac
    17941 tcttcgggat ggggagcagg cacagcaaca cccttccagg ccgcccacag gcaagccgga
    18001 tcagatgtca cctatccgtg cagcagaccc gaacagggac caggcggggt gcactgcatc
    18061 accgactacc cattgtacaa tgtcacacct catgcgtcgt gtggctacga aagggaccca
    18121 tgaactctgc gtacgcgacc gtcgaccacg tcttcaccgt ccccctcgac cacgcggccc
    18181 cgcacggccc gaccatccag atcttcgccc gagaagtcac cgaagtaggc aaagtcggtg
    18241 accagctacc ctggcttctc tatctacagg gcggccccgg cggcaagtca cccaggccct
    18301 cagccggttc acccggctgg ctgcccaggc tctcaaaacc caccgggtcc tcctcctcga
    18361 ccagcgcggc actgggcgtt ccacccccgt taccgcccgg gctgcctctc gcttcgcctc
    18421 accagcccgg ctggccgagc atctgggcca cttccgcgcc gactcgatcg tcgcggacgc
    18481 cgagctgatc cgccggcaac tgtgcggcga cgagccctgg gagactctcg gccagagcta
    18541 cggcggcttc atcaccctca cttatctgtc tcaagccccc gaaggtctgc gtgcctgcta
    18601 cgtgaccggc ggcctgcccg gcctctcggc gaccgccgac gacgtttacg cccgcaccta
    18661 tccccgggta cgggaccggg tccgcgactt ctacactcgc tatccccacg atgccgcccg
    18721 gctgcgcggg atagcccgtc tcctggccac caccgatgta cgcctgcccg acggagaccg
    18781 gctcacctcc caccgcctgc gtacgctcgg cctcgtcctc ggtatgggcg acggcttcga
    18841 gcggatccac tggcttctcg atgaagctct cgacgaggac gggaagccaa ccgacacctt
    18901 cctgcaccaa gtgctgacac tgaccggctt catcgacaat ccgctctttg ccgtcatgca
    18961 ggagaccctg tacggccagg gcgcaggtcc gaccaactgg gcggcgtcca gggccatggc
    19021 cgcgtttccg gagttcgccg aagacgccga tcctcttctg ctcaccggag agatgatcta
    19081 cccctggatg tttcgcgaga tcagtggcct gcgtccgttc gccgacgccg ccgatctgct
    19141 ggccgaacgc tccgactggc caccgctgta cgaccgtcgc cgcctcgccg ccaaccgggt
    19201 cccgctcgcc gcactcgtct accacgacga catgtacgtg gatgccgggc tctccctgtg
    19261 caccgcacgc gaggtcggcg ccacccgggt atgggtcacc aacgaatggg agcacgacgg
    19321 cgtcaccgtt gccggtgacc gcgtactgtc ccgcttgatg gacctggccg cgggacgcgc
    19381 gtagggcctt gtgccgccaa cccggtgccg cgggaaagca cggctctccg ccctaccacc
    19441 tgcgactgtc cggctcggga ccgcggctcg cgactgctgc gagccgcggt cccgagccgg
    19501 gcagacccgt tccgtcagcg cctgcggccc atcacacgcc aggccgcggg cagagccgcg
    19561 ctcgcggcga ctgccttgag cacgtcgccg acgaggaacg gcaccagtcc gtggagcacc
    19621 gcccacccga gcgactggtg cgtgacggcg gcgagcacgg gaacacccac cgcgtagatg
    19681 gctgccgagc ccgcgaggta ggccagcagc gtgccggcga cgcgccggtc ggcgccccgc
    19741 tgggcgagtg ctccgacgag gtagccggcg acgacgaacc cgagcaggta gccgccggtc
    19801 gcgccgagga cggtggacag gccgcccgtc gccccggaga agaccggcaa gcccgcggca
    19861 ccgatggcga ggtagaggag ttggcccagc gcgccgcgtg tggcacccag tgcggcagcg
    19921 gtgaccagga cggcgaacgt ctgcagtgtg acggggaccg gcgatcccgg tacgggcacc
    19981 gatatctggg cggccagcgc ggtgagcccg gcggccccga ggacgagcac ggcgtcacgg
    20041 acgcggctgc gcgcccagac ggagtcggcg agtgcgcccc gccgggggat ggcgtatgcg
    20101 acggaactca tggttgaggt ggatcccttc gaacggtggt ggcggcggca aaggctgcgt
    20161 gtcgcaggcg gttaggacag cgccgtgcgc agttgccgga cacgcgctgc ggtttccgcc
    20221 cgggcctgga gcgcttgctc catggacacc gggcagaagc gggtccggga cccgggcgcg
    20281 gactggccga cggcgtcgag gtcggcactg atcaccgttg cgaccatggc gtagccgccg
    20341 ccggagacgg catcgcggtg caggatgatg ggctccaccc cgccggggac ctggatggat
    20401 ccgagggggt atccggcgtc cacgatgttc gacgggtctg acccggcgcc gaacggctgc
    20461 actcgttcct tccactccag tgttccgccg ctgtaccgga agccgacccg gtccgcgacg
    20521 ggcgtcagcg tccatgtggt gtccagcagc gccgtgaggc cggccggggt gagccggtag
    20581 tcgtacaggc cgagcatgac gcgcagttcg agctcgcggg acagctcggg gcggaggtgc
    20641 tccggaacag ctcgccccgg ccgcccggat ccggtatcag tgccggtggc cagtacgtcc
    20701 ccggccttga gcgtgcggcc gtcgaacccg ccgaacgcgc cgagggcgta tgtcgaccgg
    20761 ctgcccagca cgagcggtac gtcgatgccc ccggacaccg cgatgtagat ccgggcgccg
    20821 tgttccagga agccgaagga gagaacgtcc ccggcgccga tatcgaagga ctcccactgt
    20881 ggcgcggacc ggccgttgac cttcactggc atcccggcgc ccgtgacggc cactactgcg
    20941 ggcgcggtga accgcagttc gggccccatg tacgcggctt cgatcagtgc ggccccgtcg
    21001 tcgttgccga ccagcaggtt cgcggccagg gccgagtaca ggtcgaccgc gcccgatggc
    21061 gggatgccga cctcgtagta gccggggcgg cccctgtcct ggatgctcga ggcaaggccg
    21121 gggttgagga tctcaatggc catgcagggc ctccagcagt gtggcgttgt aggcgtcggg
    21181 gcctgccagg aagtcgtgca ggctgaagct gaccgggctc tggcggtagc ggaatgcccc
    21241 tgcttccacg tcctgtctga cgcgctcgta ctcgtccccg tcgatcgcgc ggaacttgac
    21301 gatgtcgccg ggccggaaga agaccatgaa gtccgcgaag tcggggagct tgcgggccgg
    21361 gtcgaagatg ggtacggggg tgacgccgaa catctggtag ccgccggcgc cgcgcaccga
    21421 gtagatgcag gagaagcaac cgccgtaccc gacggtcagc gccggcgtgt cggtgcgggg
    21481 acgcaggtac ttggggactt cgagctgtcg ctcctgcgga accatctgga agaggaaggg
    21541 aaggccggcg acgaagccga ccatcgaggt gatccacggc gaaccggagt ggcggtcgat
    21601 gaacgcctgc accgaaggca ggccgttctc gatcgcggcg aactccaggt cgtttccctc
    21661 cggccgctgg tgccggtcgc ggaaccgggc accggtctcg ttggtgaacg ggtcgtcata
    21721 ccagacgggt acttcgacga tgcgggtctg gagcgtcagg gacggcgcgt cgccgacctc
    21781 ccgctcgact tggcgcaccg cgccctccag tgccgccggg gcaatgacat ccgggtcgaa
    21841 gcgcaccatg agggaggcgt tcgcgggaca gacgtcgatc acgcctggca gcttctggct
    21901 ttgcagaagc ctggccatgg ccatcgcctc gaagttgact tccaggctca ttgcctcgtc
    21961 gagctggacg accaggtgtt cgtctccgcc ccacgagtaa cggctgttga gcggactcat
    22021 gcggccctcc ctgcggcgtc gcggtcggag gcatggcctg ccatccaact ctccaggaac
    22081 gtggtgtggt agttcgcctc ggcgaactcc ggtagatcga ccagggagcg caggaacggg
    22141 gccgtggtgg ccactccccg cacctcgatc tcgtccagcg cccggcgggc gcgcgccaga
    22201 gcggcctcac gggtgtcacc ccagacgatg agtttggcga tgagcgagtc gtagaacggg
    22261 ctgacctggc tgccctgttc gcagcccgag tcgatgcgta cgaatggccc tccgggcatc
    22321 cgcatcacgg tgatcgtgcc ggggctgggc atgaatcccg cgccggggtc ctctgcgttg
    22381 agcctgaact ccagtgcatg gccgcgtggt tcgacttgtt gctgggtgaa tgacaggggg
    22441 gcgcccgcgg cgaccgtgag ctgctcgcgc accaggtccc tgccggtgac catctcggtg
    22501 acggggtgct cgacctggat gcgggtgttc atctcgatga agaagaactc ctgccgcgcg
    22561 gagtcgtaga ggaactccac cgtcccggcg ccggagtagg acactgcggc ggccaggctc
    22621 accgccgcgt tggtcatgtc ctggcgcacc tgtgcgggga ggttgggcgc gcaggcctcc
    22681 tcgaccacct tctgccggcg ccgttgcaga gagcagtcgc gctctcccag gtgtacgaag
    22741 cgctcgccgt cgccgaagac ctgcacttcg atgtggcggg cgttgtgcac gaaccgttcg
    22801 aggtagacct cgccgttgcc gaacgccgcc ttggcctcgg cctgggcgag ggggagcgcc
    22861 tcacgcagtt cggccggtga tcgcacgacg cgtataccgc ggcctccgcc gccggccgcc
    22921 gccttcaccg cgatcgggta gccgacgtgt ccggcggttt ccagggcgct gtccacgtcg
    22981 gtcagcggtc cgtcggagcc gggcacggtg ggtactcccg cgcgggcggc ggtggagcgg
    23041 gccagcgcct tgtcgcccat caggtggatg gcctcggggg acggcccgac gaacgtcatt
    23101 cccgcgtcga tgacctgctg ggcgaacgcg gcgcgctcgg agaggaaccc gtagccggga
    23161 tgcaccgcgt cggcccgcag gcggacggcg gcggccacca cggcgtcggc gtccaggtag
    23221 ctgcgggccg cgggtgcggg gccgatcacg acgtgctcgt cggccatgcg cacgtgcagg
    23281 gcctcggtgt cggtctcgct gcagaccgcg acggtccgaa catcgagttc gcgggccgcg
    23341 cgtatgaccc gtacggcgat ctcgccgcgg ttggcaacca gaagcttgcg catgttcggt
    23401 cagctcatct caatggtcgc cacgggatct cccgggccca gcagtgtctc gttctcggcg
    23461 gcgaaggcgg tcacctgtcc tccggctccg gctttgacct ccgcgaactg cttcatgatt
    23521 tcgatgattc cgatggtctg gtcctcggtg acggtcgcgc cgatctccgc gaacggcggc
    23581 ttgtccggtg cggggcgccg gtagaaga
//
