LOCUS       NC_014925              12145 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius HKU10-03, complete sequence.
ACCESSION   NC_014925
VERSION     NC_014925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius HKU10-03
  ORGANISM  Staphylococcus pseudintermedius HKU10-03
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K., Woo,P.C. and
            Yuen,K.Y.
  TITLE     Complete genome sequence of the veterinary pathogen Staphylococcus
            pseudintermedius strain HKU10-03, isolated in a case of canine
            pyoderma
  JOURNAL   J Bacteriol 193 (7), 1783-1784 (2011)
   PUBMED   21278300
REFERENCE   2  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K.P., Woo,P.C.Y.
            and Yuen,K.Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2010) Microbiology, The University of Hong Kong,
            Pokfulam Road, Hong Kong, China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000185885.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:14:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,530
            CDSs (total)                      :: 2,448
            Genes (coding)                    :: 2,410
            CDSs (with protein)               :: 2,410
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 14 of 38
            Pseudo Genes (incomplete)         :: 26 of 38
            Pseudo Genes (internal stop)      :: 5 of 38
            Pseudo Genes (multiple problems)  :: 7 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:32:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2079339
            Orig. end                         :: 2091484
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002439.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA and bacteria are available from Prof. KY Yuen
            (hkumicro@hkucc.hku.hk) at the Department of Microbiology, The
            University of Hong Kong.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12145
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="9"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..12145
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12145
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7145](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7145)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(438..1223)
                     /locus_tag="SPSINT_RS10245"
                     /old_locus_tag="SPSINT_2011"
     CDS             complement(438..1223)
                     /EC_number="3.2.1.23"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167129.1"
                     /locus_tag="SPSINT_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2011"
                     /product="beta-galactosidase"
                     /protein_id="WP_015729571.1"
                     /transl_table=11
                     /translation="MNQHLKKIEMRINQYQLTKRTRYIPYMSRHVFAIPYIKFLSHAVI
                     PLNQQWHYETETGIIHSFTDKNEMSDLHYVRSFMIEDFDDSKDYHLNIEGVQQSFMIYL
                     NQSDVGTVEGNEGHIEFDITHAVHGEMNVIELVPTETMMSPQQNLFNDMYVLERANDRI
                     VDYSVDVSQNARGDMSVRIQIQDIEGAPLISYLLQNEEHDTFAKGVMDIDSSYHLVIPA
                     HLVEQQGKHFTLFLETEDETIAHYIGANGEHEPVNVKTV"
     gene            1358..2218
                     /locus_tag="SPSINT_RS10250"
                     /old_locus_tag="SPSINT_2012"
     CDS             1358..2218
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729572.1"
                     /locus_tag="SPSINT_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2012"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_015729572.1"
                     /transl_table=11
                     /translation="MQLLWKMFKKNQFEANIDECGIEIGTPHGGYQYEVTKPAVLHIVM
                     SGTGTLTYNQKKYTLKPGDLFLLCRGMNVHYESTLDEPWTYYWVGFSGKLVFDYLNRTS
                     LYETRVIQNQPTNTIRQIIYRMCQRSIEYATENSDDIQHMRDLYELLYELHQHFPKPFH
                     VVKNERYSNVREAIRYINDNYMHAISINDVAKHVNVSRSYLYKMFKKHIDQSPQHYLIH
                     IRMYHASQLFKETDLQSQEIADRVGYKDPLLFSRAFKKHFGVTATQYREEQQLRIESTL
                     DNQKR"
     gene            2390..3601
                     /gene="gltS"
                     /locus_tag="SPSINT_RS10255"
                     /old_locus_tag="SPSINT_2013"
     CDS             2390..3601
                     /GO_function="GO:0015501 - glutamate:sodium symporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015813 - L-glutamate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="gltS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169590.1"
                     /locus_tag="SPSINT_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2013"
                     /product="sodium/glutamate symporter"
                     /protein_id="WP_015729573.1"
                     /transl_table=11
                     /translation="MLELNSITTLFLACLLLIVGQAIVNKVEIFNRLSIPSPVIGGLIF
                     AIISAILTSTGVLHIKIDGKFFQDFFMLAFFTTIGLGASFKLLKLGGKVLIVYWVLCGV
                     LATFQNVIGVSIAKVLNIDPLLGLTAGAMSMEGGHGNAAAYGQTIQNYGIDSAVTAALA
                     AATLGLVAGGLLGGPVVRYLIKKHDLAPSNAETIQKDYSNVEINRRLHKHFTVNEVFFI
                     QATVILFCMGLGSYLGQLFSDWSGINIPLYVASMFIAVIIRNISEFANLNLIDLKLTNQ
                     IGDISLSIFLSIALMSIKLTEVYNLALPLIVIVICQIIFVALFSIFIVFRLLGKNYDAA
                     VMIGGFIGHGLGATPNAMANLDAITKKFGNSPRAYLVVPIVGAFLVDLLGFPIITTFIN
                     IFKP"
     gene            complement(3755..>3916)
                     /locus_tag="SPSINT_RS12865"
                     /pseudo=""
     CDS             complement(3755..>3916)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558285.1"
                     /locus_tag="SPSINT_RS12865"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SLASETFYLNSELRSSNTIVIDIVESYIENYNKVRIQQKLGYLSP
                     IEYRKLAA"
     gene            complement(<4107..4505)
                     /locus_tag="SPSINT_RS10260"
                     /old_locus_tag="SPSINT_2014"
                     /pseudo=""
     CDS             complement(<4107..4505)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031600262.1"
                     /locus_tag="SPSINT_RS10260"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2014"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MMARKKRNPKSVELANRIISEYAPETVEDMEEALKDIFGPMFEAI
                     LQGEMNNHLGYSSNDKSDKSTENMRNGYGNKTLKTSKGEVEINVPRDRDASFAPKLIKK
                     RQRDVSEIEAKVISMYAKGMSQRDIHSAI"
     gene            complement(5001..7145)
                     /locus_tag="SPSINT_RS10265"
                     /old_locus_tag="SPSINT_2015"
     CDS             complement(5001..7145)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613109.1"
                     /locus_tag="SPSINT_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2015"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_014613109.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 2e-36, bitscore:
                     121.9, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 7e-175, bitscore:
                     580.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKLIRQFDETDCGPTCLAMISRYYGKNVSVTKIRELAKTDKFG
                     TSIFGLIQAGKELGLLVEAYELDEIKELEVFNHPIIAHVKTQNNFEHFIVIEKTLNGKV
                     IIKDPDKGSYSLTYEEFYEIFTLIILDINKEKHFSKSNEVTTVRKVLMPLLKNNVKFLI
                     LIIVISLLINLVGIAGALYFQYLIDDIIPIEDFHALHKVSASILLLYFINLFVSFFRYY
                     LSLKISLNIDYSLMKKYYNHVIKLPSSFFDNRKTGEILSRFNDIHNIRESLSSVTVTLF
                     VDLILVLGGSIILYQESGILLLLCSCILPIYIILSLVLKRPFEINNRKLMEESAVLSSY
                     LIESFENNLIIKSYNYENDMYSRGKKRFNSLVNKALKLGLYNNYQLSISNFVNIFISLI
                     VLWVGSYLVIDKELTLGSLIAFNALLIYFLDPFERIINMQPIIQSSIVAIKRVGEIFDL
                     ETEKREKSMFRPLQNAIVFNDVCFQYGFRRDILSNVNMTFTKGKKVGIVGSSGSGKSTI
                     GKLLIQLYSCQNGNIYWDGKPIEDLSLMKLRDNIGYVPQDDFWFNGSIIENLTLNKKNV
                     SKEVVIQACKESGAHDFISDLTNKYESIIENGGGNLSGGQKQKLSIARALIKDPDIYIF
                     DEPTSSLDTLSEYKILELLEKLSSNNKTIILISHKLKSIANSDYIYVLKHGRIIEEGSH
                     NELIFNGSEYKSLWEKQCAR"
     misc_feature    7137..7151
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.76"
                     /tool="antismash"
     misc_feature    complement(7237..7250)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.0"
                     /tool="antismash"
     gene            7281..7433
                     /locus_tag="SPSINT_RS10270"
                     /old_locus_tag="SPSINT_2016"
     CDS             7281..7433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613108.1"
                     /locus_tag="SPSINT_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2016"
                     /product="hypothetical protein"
                     /protein_id="WP_014613108.1"
                     /transl_table=11
                     /translation="MKNLSSKQLKEISGGGRIAESIGYGIGIGLACIGDSKCAARKLNK
                     LSNKK"
     gene            7446..7607
                     /locus_tag="SPSINT_RS13065"
                     /old_locus_tag="SPSINT_2017"
     CDS             7446..7607
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SPSINT_RS13065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SPSINT_2017"
                     /product="hypothetical protein"
                     /protein_id="WP_014613107.1"
                     /transl_table=11
                     /translation="MKKIKSIDSLCKINGGRRRAAREVGNFVRDYIIGKGIDHAGEIYR
                     AAKKAYKA"
     gene            complement(7768..8973)
                     /locus_tag="SPSINT_RS10275"
                     /old_locus_tag="SPSINT_2018"
     CDS             complement(7768..8973)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178: cobalamin synthesis protein/P47K family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169589.1"
                     /locus_tag="SPSINT_RS10275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2018"
                     /product="GTP-binding protein"
                     /protein_id="WP_015729574.1"
                     /transl_table=11
                     /translation="MGKIPVTVLSGYLGSGKTTLLNHILNNREGRRIAVIVNDMSEVNI
                     DKDLVAEGGGLSRTDEKLVELSNGCICCTLRDDLLKEVERIVKRGGIDQIVIESTGISE
                     PVPVAQTFSYVDEALGIDLTEICRLDTMVTVVDANRFIKDYQSGDMLLDRDQAVGEDDE
                     RTIADLLIDQIEFCDVLILNKIDLVSEEEANRLEAMLRKLQPTAKLIRTVNAEVNIDEV
                     LETGRFNFEAASQSAGWLQELEAGGHATHTPETEEYGISSFVYRRRLPFHAERFNAFLE
                     NMSESIVRAKGIAWLAQYNDVACLVSQAGTAVDIHPVTFWVASMPKAERAAILQERPDV
                     RADWDPEYGDRHTQLVIIGIDLDEAAITAELDECLLNSQEIDAEWSQLFDPYGWEIRRQ
                     EA"
     gene            complement(9147..10178)
                     /gene="fni"
                     /locus_tag="SPSINT_RS10280"
                     /old_locus_tag="SPSINT_2019"
     CDS             complement(9147..10178)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019169588.1"
                     /locus_tag="SPSINT_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2019"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_015729575.1"
                     /transl_table=11
                     /translation="MTNKREQRKNEHVRLALAQSDTLQSDFDRIQFVHHAIPEMNVDEV
                     TLLPNFKALHMSHVLYINAMTGGSEWTVKTNEQLAQVAKATQIPMAVGSMHAALKNPAV
                     RHSYTVAREQYPEGQIWANVSADVTLEEAQAAIEMIHANALQIHVNAPQELVMPEGNRQ
                     FKHWLTRISEIIKGVEVPVIVKEVGFGMSYDTIQQLIDVGVSYVDISGHGGTNFISIEN
                     ERRQFKDMGYLKDWGQSTVVSLLEARNLSSRVHVLASGGIRHPLDAIKALRLGAEAVGM
                     SRPILKILHEEGVEATIEYVEDFKTQMAYIMTLLNAKNITELRQAAIVFDPHLKNWIQQ
                     RQL"
     gene            10356..10832
                     /locus_tag="SPSINT_RS10285"
                     /old_locus_tag="SPSINT_2020"
     CDS             10356..10832
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729576.1"
                     /locus_tag="SPSINT_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2020"
                     /product="thioesterase family protein"
                     /protein_id="WP_015729576.1"
                     /sec_met_domain="4HBT_2 (E-value: 5.3e-31, bitscore: 104.8,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNYPFYDTYRVENDWIDRNGHMNDAVYARLFSLAIDHFHDAIGL
                     TTAERDRRNYTVFTLETHITYLKELKHDTPFHIKVHIYDYDVKRTHFFLELIHQETETV
                     MATAETMMMGMDRKTERPAVFPDDIFHAIQHYANSQGTMQWPKQLGHRIGIPRA"
     gene            complement(10891..11877)
                     /locus_tag="SPSINT_RS10290"
                     /old_locus_tag="SPSINT_2021"
     CDS             complement(10891..11877)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364852.1"
                     /locus_tag="SPSINT_RS10290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_2021"
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="WP_225550179.1"
                     /transl_table=11
                     /translation="MFTLFTYKAPNGMRAMGALANAAIATFLVEAFNKYVGGRVFHNDF
                     LEQVGAAAGDLGGVAAAGLTALAIGVSPVYALVIAAACGGMDLLPGFFAGYLIGYLMKY
                     TEKYVPDGVDLIVAVLIVAPLSRAIAMLLTPVVNNTLVRIGDIIQSSTDTSPVIMGIIL
                     GGIITVVGTAPLSSMALTALLGLTGVPMAIGAMAAFSSAFMNGTLFHRLKLGDRKATIS
                     VSIEPLSQADIVSANPIPIYITNFFGGATAGLVIALSGLINDATGTATPIAGFIVMFGF
                     NSWVTVVVYGVIMGIIGLIWGYIGSIVFKKYPIVTKADMIKRGATDA"
     misc_feature    complement(11817..11831)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.04"
                     /tool="antismash"
     misc_feature    11818..11832
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.92"
                     /tool="antismash"
     gene            11840..>11923
                     /locus_tag="SPSINT_RS13245"
                     /pseudo=""
     CDS             11840..>11923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498879.1"
                     /locus_tag="SPSINT_RS13245"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPLGALYVNNVKMTSTKTKNAVPISKSI"
ORIGIN
        1 taaccgctga ttccctacac gtgtgagttc ataatattta cgcgcaggtc cttccattga
       61 tggttcgtaa taggtcgtca aacaactttc tttaacaagt cgacgtaata acggataaac
      121 cgtaccttca gcaatcatca tatgcttaga aatattttgt acgagtgagt agccatactg
      181 tggctccttt ttaataatca acagtacaat catttctaat gcaccttttt tgaattggat
      241 gttcattgtt gcacctccat caatacatta atcagtacta accaatgtat aatactcaaa
      301 tataaaatac caaacactat tatacattgc aaggtactgt gtaaaattca tttgaacggc
      361 tataggtctc tgctcaaaac caataaaaaa tgcgtaccag gggctttcat cacctagata
      421 cgctttcaaa tggtatttta aactgttttg acattgaccg gctcatgttc gccattcgct
      481 ccaatataat gtgcaatcgt ttcatcttct gtctctaaaa acaacgtgaa atgtttccct
      541 tgttgctcta ctaaatgtgc cggaatcact aaatggtaac tgctatcaat gtccattacc
      601 cctttagcaa atgtgtcgtg ttcttcgttt tgcaataaat agctgattaa tggggcccct
      661 tcgatatctt gaatttgaat acgcacactc atatcaccac gcgcattttg gctcacatcg
      721 acagaataat ccacaattcg atcgttcgcc ctttcgagta cgtacatatc gttaaacaga
      781 ttttgttgtg gggacatcat cgtttctgtt ggcaccagtt caatgacatt catttcacca
      841 tgaacagcat gtgttatatc aaactcgata tgcccttcat tgccctctac cgttccaaca
      901 tcactttgat tcaaataaat cataaaagat tgctgtaccc cttcaatatt taaatgataa
      961 tctttactgt catcaaaatc ttcaatcata aaagaacgta catagtgcaa gtccgacatt
     1021 tcatttttat ccgtaaatga atgtatgatg ccagtttcag tttcatagtg ccattgttga
     1081 tttaaaggta ttaccgcatg acttaaaaat ttgatatatg gtatcgcaaa tacatgacga
     1141 ctcatgtacg gaatataacg cgttctttta gttaattgat attgattaat tcgcatctct
     1201 atctttttca aatgctggtt catctcatca ccccagtgtt aaaatatata tttttttgtg
     1261 cttttaattt aacactttag acttaaagag aatatatacc aatcgtcact gtatatgtta
     1321 aaatgtttcc atatttaaag ttaaatgggt gggataaatg caattactct ggaagatgtt
     1381 taaaaagaat caatttgaag ccaatattga tgaatgtggc attgaaatcg gaacaccaca
     1441 tgggggttat caatatgagg tgaccaaacc agcagtgctc catattgtca tgtctggaac
     1501 gggtacgctc acatacaatc aaaagaagta tacattgaaa ccgggtgatc tcttcttact
     1561 ttgtcgtggc atgaacgtcc actatgaatc cactttggac gagccgtgga catattattg
     1621 ggtaggtttt agcggaaaac tcgtttttga ttatttaaac cgtacatctt tatatgaaac
     1681 acgcgtcatt caaaatcaac caacgaacac cattcgccaa atcatatatc ggatgtgtca
     1741 gcgttctatt gaatacgcca cagaaaactc tgatgatatt caacatatgc gcgatttata
     1801 cgaactccta tatgaactgc atcaacattt tcccaaaccg tttcatgtcg ttaaaaatga
     1861 aagatattct aacgttagag aagcgattcg ttatattaat gacaattata tgcatgcgat
     1921 ttcgattaat gatgtcgcca agcacgtcaa tgtcagccgt agttacctat ataaaatgtt
     1981 taaaaagcac atcgatcaat ccccgcaaca ttatttaatt catattcgga tgtatcacgc
     2041 atcacaatta ttcaaggaaa cagatttgca aagtcaagaa attgcagatc gtgtaggata
     2101 taaagatcca ttactatttt cgagagcatt taaaaaacat tttggtgtca cggcgaccca
     2161 atatcgtgaa gaacagcagt taagaattga aagtacattg gacaatcaaa aacggtgata
     2221 caacccaatg atcaactact cactatttaa aggtatatat ctactcactt cgaacaatca
     2281 tactcgattt gatttttata tagatttttg cctttaaaaa aagtataata gtttagtatg
     2341 ggattgaaag ccctttctat tttactaact caaagggggg agtgtaacaa tgttagagct
     2401 taacagtatt acaacattgt ttcttgcctg tctattatta attgtggggc aagctattgt
     2461 gaataaagta gaaatattta atcgtctcag cattccatct cccgtcatag gtggactcat
     2521 ctttgcgatt atctctgcaa tattaacttc taccggggta ttacacatca aaatcgatgg
     2581 caaatttttc caagactttt ttatgttagc ctttttcaca acaattggat taggggcgtc
     2641 atttaaatta ttaaaactcg gtggcaaagt gttaattgtc tactgggttc tctgtggtgt
     2701 gttagcgacc ttccaaaacg tcattggtgt gtccattgca aaagtgttga acattgatcc
     2761 gctattaggt ttaacagcgg gtgcgatgtc aatggaaggt ggacacggga atgcagcagc
     2821 gtatggtcaa acgattcaaa attatggtat tgactcagct gtgacagccg cacttgcagc
     2881 agcgacacta ggtcttgtag cgggtggtct attaggtgga ccagtcgtac gttatttaat
     2941 taaaaagcat gacttagcac caagtaatgc agaaacaatt caaaaagact attcaaatgt
     3001 agagatcaac cgacgtctcc ataaacactt tactgtgaat gaagtgtttt ttattcaagc
     3061 gacagtcata ttattctgta tgggactcgg ctcatattta ggtcaattat tcagtgactg
     3121 gtcaggaatc aatattccat tatatgttgc ttcaatgttt attgcagtaa ttattcgtaa
     3181 catttcggaa tttgcaaatc taaacttaat cgacttaaaa ctcacaaatc aaattggcga
     3241 catttcatta agtattttct tatcaattgc gttaatgagt attaagttaa cagaagtata
     3301 caacttagca ttaccactga ttgttatcgt tatatgccaa attattttcg tcgcactatt
     3361 ctctattttc atcgtcttcc gcttgctcgg taaaaactat gatgcagccg tgatgattgg
     3421 tggtttcatc ggacacgggc ttggcgcgac accgaatgca atggccaatt tagatgccat
     3481 tacgaaaaag tttggcaact caccacgtgc ctatctagtc gtaccgattg ttggcgcatt
     3541 tttagtcgat ttgcttggct ttccaattat cacgacattt attaacatct ttaaaccata
     3601 atttccaaca cattaacagg ctcgtatcaa aatgagcctg ggatatatat tacagtaatt
     3661 ggggctggga catagggttt cagttcccaa gaaaaacacc acaaaattct ggtactgcat
     3721 ccttactaag cgagctcaat aaaaaaacta ttttctaggc tgctaatttc ctatattcta
     3781 taggggataa gtagcctagt ttttgttgaa ttctaacttt attatagttt tcaatgtaac
     3841 tttcgacaat atctattaca atagtattag agcttctgag ttcactgttt aagtagaatg
     3901 tttctgatgc tagactaaga aacggatacg gtaaattgat aagaatttca tttataataa
     3961 aagaaatcaa ttgataggcg tgtcaatgat ggcgagaaga aaatacgatc atagctttaa
     4021 aatggaagca attcaataag tagaatcagg gagacgtgcc tcagaagttt ctagagatct
     4081 agatattcct attcaaacgt taacaaaatg gctgagtgaa tatcacgttg agacattcct
     4141 ttggcataca tagaaattac tttagcttca atttccgaaa catctcgttg gcgcttcttg
     4201 attaattttg gagcaaatga agcatctcta tctctgggta cattaatttc aacttctcct
     4261 ttagaagttt ttaatgtctt atttccatag ccattacgca tattttcagt agatttgtca
     4321 gatttatcat tcgaagaata acctagatga ttattcattt caccttgtaa tatagcttca
     4381 aacatgggtc cgaaaatatc ctttaacgcc tcttccatat cttcaacagt ttcgggagca
     4441 tactcagaaa taattctatt agctaattca acagatttag gattacgttt tttacgagcc
     4501 atcatgttac ctccatagta tcttaagtgt attttaacac tatgcataga gttatgctta
     4561 gaatccgtaa aaagtgattg gtttgttttt taaccaacac tttttatgga tttagcaagc
     4621 gttagcgcgc taggaaaata aaaaataaac tgtgaagcag agtcgtacgc actctactta
     4681 cacagtttat tttacattct cttttttggc tgggaattat gtcccagctc cggctctatg
     4741 tcaaattctt ttagtgctta aaaattcaat ctatgctata atgtctcttt taagttcttt
     4801 gaagctatcc tatcataatt ttttaaataa tacatttccg ctttgatggc accccaaaaa
     4861 ccttccatag aactattatc aatacagcta tcaactcttg acgtactgta tatcacatca
     4921 agctctctta acaaggaacc gagaaaatag cattttcatt tcgccactcc cctacattta
     4981 taaccaccat ttacaacatc ttacctagca cattgcttct cccacaatga cttatattca
     5041 ctaccattaa aaatcaattc gttatgggaa ccttcttcaa taatcctccc atgtttcaat
     5101 acgtatatat aatccgaatt tgctatactc tttaatttat gagaaattaa aatgattgtt
     5161 ttattatttg aagatagttt ttctaataac tctaatattt tatattcaga taaagtatcc
     5221 aaagaactag ttggttcatc aaatatataa atatcaggat ctttaataag agcacgcgct
     5281 atggataatt tctgtttttg accacctgac aaattccccc ccccgttttc gataattgat
     5341 tcatatttgt tagtaaggtc acttataaaa tcatgtgctc ctgattcttt acaagcttga
     5401 ataactactt cttttgaaac attttttttg tttaaagtta ggttttcaat aatagaacca
     5461 ttgaaccaaa aatcatcttg tggcacatat ccaatattat ccctcaattt cataagtgat
     5521 aaatcttcta ttggttttcc atcccaataa atattcccat tctgacaact ataaagttgt
     5581 attagtaatt ttccaattgt agattttccc gatccacttg atccaacaat acctactttt
     5641 ttccctttag taaaggtcat attaacattt gataatatat ctcttctaaa gccatattga
     5701 aagcaaacat cattaaaaac aattgcattt tgcaatggac gaaacatact tttttctctt
     5761 ttttcagttt ccaaatcaaa aatttcgcct acacgcttaa ttgcaactat agatgattgt
     5821 ataattggtt gcatatttat aattctttca aatggatcta aaaaataaat taataacgca
     5881 ttaaatgcta ttaaagagcc taaagttaat tccttgtcaa taactaaata tgaaccaacc
     5941 cataagacta tcagactgat aaaaatattt acaaagttac ttattgataa ttgataattg
     6001 ttatataacc ctaactttaa tgctttattt acaagagagt taaatctttt cttcccccta
     6061 ctatacatat cattctcata attataactt tttattatta aattattttc aaatgattca
     6121 attaaatacg agcttaatac tgcactttct tccattaatt ttctattatt tatttcaaat
     6181 ggtcttttta aaactaaaga taaaatgatg taaataggaa gaatacaaga acatagtaga
     6241 agtaatattc cactttcttg ataaagaata atactgcctc ccaaaacaag tataagatca
     6301 acaaataaag ttactgttac tgaagataat gattccctaa tattgtgaat gtcgttaaaa
     6361 cgtgatagta tttctccagt ttttctattg tcaaaaaaac tgctaggtaa ttttattaca
     6421 tgattataat attttttcat aagactataa tcaatattca aacttatttt caaactaaga
     6481 taatatctga agaatgatac aaataaatta ataaaatata ataataatat tgacgctgaa
     6541 accttatgta aagcatgaaa atcttcaata ggtattatat catcgattag atattgaaag
     6601 tataaagctc ctgcaattcc tactaaattt attaataatg aaatgacaat tatcaatatt
     6661 aaaaatttaa cattattttt tagcaatggc attaaaactt ttctaaccgt tgtaacttca
     6721 ttagattttg aaaagtgctt ctctttatta atatctaaaa taattaatgt aaatatctca
     6781 taaaattctt catatgttaa tgaataactt cctttatctg gatctttaat aattactttg
     6841 ccatttaagg ttttttcaat cacaataaag tgctcaaagt tattttgagt ttttacgtgt
     6901 gctattattg ggtgattaaa aacctctagc tcttttattt catctaattc atatgcttca
     6961 actaataaac ctaattcctt tcctgcttga atcagaccaa aaatactagt tccaaattta
     7021 tccgttttag ctagttctct tattttagta actgaaacat ttttaccgta atatctgctt
     7081 atcattgcta aacacgtagg tccacaatcc gtttcatcaa attgtcttat taatttaatt
     7141 ttcataaaat gactcccaaa acttttatat ataccaataa aacaatatac tataccgaaa
     7201 taaatctatc aatattacac caattaaatt tattgatttt tctaaaaaat ggggttatat
     7261 ttattatggg aggtgatttc atgaagaatt taagttcaaa acagcttaaa gagatatctg
     7321 gtggcggtag aatagccgaa tcaattggct atggcattgg tattggtctt gcttgcatag
     7381 gtgactcaaa atgtgcagct cgtaaactta ataaattatc aaacaaaaaa tagggagtgg
     7441 ggtttttgaa aaaaattaaa agtattgatt cactttgtaa aattaatggt ggtagacgaa
     7501 gagctgccag agaggtagga aatttcgtac gtgattacat aatcggaaag ggaattgatc
     7561 acgctggtga aatttataga gcagctaaaa aagcttataa agcttaaaca aggtaaaata
     7621 ctacaaaaat aaaacttttc atagtttaca ctatagtaga acgaaccgat taaaatttga
     7681 ttttcttaat cggttctatt tcactgaact aagattcttt taattatttt aaatcattat
     7741 tcgaactcgt aaaatatttt tattttgcta tgcttcttga cggcggattt cccaaccgta
     7801 cggatcaaac aactgtgacc attcggcatc aatttcttga ctgttcaata agcattcatc
     7861 taattcggca gtaatcgctg cttcatctaa atcaattcca ataatgacga gttgcgtatg
     7921 gcgatcacca tattcagggt cccaatccgc acgcacatcc ggtctttctt gcaaaatggc
     7981 cgcacgttca gcttttggca tgctggctac ccaaaatgtc acaggatgaa tatcgacagc
     8041 cgttcctgct tgagaaacaa gacacgcgac atcattgtat tgtgctaacc aagcaattcc
     8101 tttcgcacgg acaatggatt cagacatatt ttcaagaaaa gcgttaaagc gttctgcgtg
     8161 aaatggcaaa cgtctgcgat aaacaaatga cgaaatacca tattcttcag tttcaggtgt
     8221 atgtgtcgca tgtccacccg cttcaagttc ttgtaaccac cccgctgatt gactcgccgc
     8281 ttcaaaatta aagcgccctg tttctaatac ttcgtcaatg ttcacttctg cattgaccgt
     8341 gcggattaac ttcgcagtcg gttgtaattt acgcaacatc gcttctaaac gattcgcctc
     8401 ttcttcactg actaagtcga ttttattcaa gatgagcaca tcacaaaatt caatttgatc
     8461 gatgagtaaa tctgcaatcg tacgttcgtc atcttcaccc accgcttgat ctcgatctaa
     8521 taacatgtct ccagattgat agtctttaat aaatcggttt gcatcgacaa cggttaccat
     8581 cgtgtcgaga cgacaaattt ccgttaaatc aatccctagc gcttcgtcca cgtaagaaaa
     8641 tgtttgcgct acaggaaccg gttcagaaat ccctgtcgat tcaataacga tttgatcaat
     8701 gccgccacgc ttgacgatac gttcgacctc ttttaataaa tcatcgcgca atgtacaaca
     8761 aatacaaccg ttcgaaagtt caacgagttt ttcatctgta cgtgaaaggc cccctccttc
     8821 agcgacaaga tctttatcaa tatttacctc actcatatcg ttcacaataa cagcaattct
     8881 tcttccctcg cgattgttta aaatatgatt cagcaaagtc gtcttacctg atcctaaata
     8941 cccacttaat accgttactg ggattttccc cataaatagc cctcctcatt tcattacaaa
     9001 tcgtaataat tacgttttac agtatataat aaatacttcc atcaacgcaa tgaaaatttg
     9061 aaatgatttt tgggctgacc cgttaactgt attaaaaaag gaacgaatga cggcgtgatg
     9121 acaccctcat gcattcctca gttcgactac aattgacgct gttgtatcca gttttttaaa
     9181 tgcggatcaa acacaatcgc cgcttgacgc aattctgtga tatttttggc attcaataaa
     9241 gtcataatat aagccatttg tgttttaaaa tcttctacat attcaatcgt cgcttccacg
     9301 ccctcttcat gaagtatctt taaaatcggt cgcgacatac ccactgcttc tgcacctaaa
     9361 cgtaatgctt taatcgcatc aagtgggtgg cgtatccctc cacttgcaag tacatggacg
     9421 cgactgctca aatttcgggc ttctaataat gaaacgactg tcgattgccc ccagtctttt
     9481 aaataaccca tatctttaaa ttggcgacgt tcattttcta ttgagataaa gttcgttcca
     9541 ccatgaccac taatgtcaac ataagagacg cctacatcga taagttgttg tatcgtgtca
     9601 tagctcatcc caaagcccac ttctttcaca atgaccggta cctcgacgcc tttaataatt
     9661 tcactgattc gcgttaacca atgtttgaat tgtcgattcc cctctggcat gactaactct
     9721 tgtggtgcgt taacatgaat ttgtaacgca ttggcatgaa tcatctcaat cgccgcttgt
     9781 gcttcttcca acgtcacgtc cgcactcaca ttcgcccaaa tttgaccctc tggatattgt
     9841 tcacgagcca ctgtataaga atgccgtaca gctggatttt tcaacgcggc atgcatactt
     9901 cctacagcca ttggaatttg tgtagcttta gcgacttgag ccaattgttc attcgttttt
     9961 accgtccatt cagaaccacc cgtcatcgca ttaatataga ggacgtgtga catatggagt
    10021 gctttaaagt taggcaacag tgtcacctca tctacattca tttccggtat tgcatgatga
    10081 acaaattgaa tgcgatcaaa atcggattgt agcgtatcac tttgcgcgag tgctaatcgt
    10141 acatgttcat tttttctttg ttctctttta ttcgtcatta ccttaaaaac ccctcattat
    10201 tggttgatta atttgactat atcatattca gtgccgacat aaagtatttt cttgaaatca
    10261 acatattaaa aaagaaatat ggggatgtca cactgtttta tctctttaac attttgcggt
    10321 atactgatga acaaataaaa caaagaggtg tccctatgtt caattaccct ttttatgata
    10381 catatcgcgt tgaaaatgat tggattgatc gcaatggtca tatgaatgat gctgtttatg
    10441 caagactttt tagtttagcc atcgatcatt ttcatgatgc cattgggtta acaacagcag
    10501 aacgcgaccg tcgaaactac acggttttca ctttagaaac tcatattacg taccttaaag
    10561 aactaaagca tgatacaccc tttcacatta aagttcacat ttatgattat gatgtcaaac
    10621 gcacacactt ctttttagag ctgattcatc aagaaacaga aactgtcatg gccactgcag
    10681 aaacgatgat gatgggtatg gatcgaaaaa cagagcgccc agcagtgttt cctgacgata
    10741 ttttccacgc aattcaacac tatgctaact cacaaggaac gatgcagtgg ccaaaacaat
    10801 tgggacaccg aattggcatt cctcgcgcat aaattcaaaa aacactacaa gtcctcgtca
    10861 cagcttgtag tgttttgtta tgttattcaa ttatgcgtct gttgcaccac gtttaatcat
    10921 gtctgcttta gtgacaattg gatatttttt aaagacaata gagccgatat agccccaaat
    10981 aagtccaata atccccatga tgacaccata cacgaccaca gtcacccaag aattaaaacc
    11041 aaacatgacg ataaagccgg caatcggagt cgctgtccct gtcgcatcgt taatcaaacc
    11101 ggaaagtgca atgacaagac ctgccgtcgc accaccaaaa aagttcgtaa tataaattgg
    11161 aatcggattg gccgaaacga tatctgcttg tgacaacggt tcaatactca ctgaaatcgt
    11221 cgctttacgg tcacctaatt ttaaacggtg gaacagtgta ccgttcataa atgcagaact
    11281 aaatgcggcc atcgcaccaa tagccattgg cacacctgtt aaacctagca gtgcggtcaa
    11341 cgccatcgaa cttagtggcg ctgtaccgac gacagtaata atgccaccta aaataatccc
    11401 cataatgacc gggcttgtat ctgtagaact ttgaataatg tcaccaattc taacgagtgt
    11461 attgttgaca acaggtgtta atagcatcgc gatcgctctt gataatggtg caacgattaa
    11521 tacagcaaca ataagatcca caccgtctgg cacgtatttc tcagtatatt tcattaaata
    11581 accgataaga taacccgcaa aaaatcctgg taataaatcc atacccccac aagctgccgc
    11641 aatcactaag gcgtaaacgg gcgaaacacc aatggctaaa gccgtcagac ccgctgcagc
    11701 aacaccacct aagtcacccg ctgcagcacc cacttgttct aaaaagtcat tgtggaacac
    11761 gcggccgccg acgtatttat taaaagcttc aactaaaaat gtcgcaatgg ctgcattcgc
    11821 aagcgctccc atcgcacgca taccattagg cgctttatat gtaaataatg tgaaaatgac
    11881 gagtactaaa actaaaaatg ctgtaccgat aagtaagtcc ataatgcccc cctcttgtta
    11941 ttcgaaaaag gccccttgtt catcatttca atttttgaat aactgtataa tttttatagt
    12001 ttatttattc atgtatttca ttttactaaa gttttttgtt ttttgcacgc cagtttgatt
    12061 ttgaactttc taaaaatgaa tcttaatagt caatttactg accgtcattt caattcttat
    12121 aaacattagc acccattttc cacct
//
