LOCUS       NC_014925              33000 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius HKU10-03, complete sequence.
ACCESSION   NC_014925
VERSION     NC_014925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius HKU10-03
  ORGANISM  Staphylococcus pseudintermedius HKU10-03
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K., Woo,P.C. and
            Yuen,K.Y.
  TITLE     Complete genome sequence of the veterinary pathogen Staphylococcus
            pseudintermedius strain HKU10-03, isolated in a case of canine
            pyoderma
  JOURNAL   J Bacteriol 193 (7), 1783-1784 (2011)
   PUBMED   21278300
REFERENCE   2  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K.P., Woo,P.C.Y.
            and Yuen,K.Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2010) Microbiology, The University of Hong Kong,
            Pokfulam Road, Hong Kong, China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000185885.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:14:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,530
            CDSs (total)                      :: 2,448
            Genes (coding)                    :: 2,410
            CDSs (with protein)               :: 2,410
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 14 of 38
            Pseudo Genes (incomplete)         :: 26 of 38
            Pseudo Genes (internal stop)      :: 5 of 38
            Pseudo Genes (multiple problems)  :: 7 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:32:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1911151
            Orig. end                         :: 1944151
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002439.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA and bacteria are available from Prof. KY Yuen
            (hkumicro@hkucc.hku.hk) at the Department of Microbiology, The
            University of Hong Kong.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..33000
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="8"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..33000
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..33000
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:19000]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..19000
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            complement(706..2154)
                     /locus_tag="SPSINT_RS09370"
                     /old_locus_tag="SPSINT_1828"
     CDS             complement(706..2154)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168477.1"
                     /locus_tag="SPSINT_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1828"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_015729473.1"
                     /transl_table=11
                     /translation="MHKGVHVDKTQRNIIVAVILISAFIAILNQTLLNTALPSIMRGLD
                     IHESTSQWLVTGFMLVNGIMIPLTAYLMDRVPTRTLYLTAMGTFVVGSITAALAPSFSI
                     LMTARVIQALGAGVIMPLSQFTLFTLFPKNQRGFAMGLSGLVIQFAPAIGPTLSGVLVD
                     NYSWRSPLFVVVVVSIIGLIFGWRYMRNFSDTKEVVLDKASVVLSTLGFGIMLYGFSIA
                     GTRGFDDLIVLISLIVGIAIVALFITRQLRIDNPILRLSAFRTRTFTLTSISSMIVFTS
                     MVGPALLIPIYIQNSLGLSALLSGLVVLPGAVINGVMSVVNGRLYDKVGARVLVIPGFA
                     LLLITTLMMAQLTAHTSYTYVIIIFTIRLFSVSLLMMPLNTAGINALPNDMVSHGTAIM
                     NTLRTISGSMGTALMVTLMSLGAGLYQPDASVSKTMIQREAMAHGVDLAFYVTSGFLLI
                     GFILSFFIHDRGKKERGHQRHVVR"
     gene            complement(2260..2721)
                     /locus_tag="SPSINT_RS09375"
                     /old_locus_tag="SPSINT_1829"
     CDS             complement(2260..2721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168476.1"
                     /locus_tag="SPSINT_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1829"
                     /product="SepA family multidrug efflux transporter"
                     /protein_id="WP_015729474.1"
                     /transl_table=11
                     /translation="MKGKFNLFNFVALLIILSIFVISGAIFLTLLGFGLFGLSRLLIYF
                     RLGMFTYNEGFYDNLIYYGSYIILGYFVIFGVEYLMDWLQKKLYPNPYLEGFTFHLISY
                     AMMITMFYFVIHIHYQYIQIDYWVLMLIIAFLYICKEVFYPDAEDLNRK"
     gene            complement(2747..4090)
                     /gene="sdrM"
                     /locus_tag="SPSINT_RS09380"
                     /old_locus_tag="SPSINT_1830"
     CDS             complement(2747..4090)
                     /codon_start=1
                     /gene="sdrM"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016426404.1"
                     /locus_tag="SPSINT_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1830"
                     /product="multidrug efflux MFS transporter SdrM"
                     /protein_id="WP_041614878.1"
                     /transl_table=11
                     /translation="MNLKQVSIICSLVLTMFMAAIETSIVSLALPTMRADLHATQPISL
                     VFTVYFVGIVLSIPILSELMSRIKIIYVTMLGLILFLVGSFLSGMSSHFEMLVFARLLQ
                     GVGAGVNMSLVQIVPKLAFEIPFRYKVMGIVGSVWGISSILGPFLGGFILEVSSWHWLF
                     YINIPIAVIVMLLVLTSYHFESESTSKHKVDFVGMGLFYVLLALLMASVLITGHIWMNV
                     VCLVLFVIFFGVTIKRSKKVSLSFIPTKEFDSKVRLAFFTDFFIAVTLIGFNVFIPSYL
                     QDHLGLTPLQSGLIIFPLSIGWLLINFTLEIIEANRTVRGLYLLAIGILIVGSISVLIG
                     AFYPIVVAMTLFFLGMSFGTAYTKDSVMVQEETFPESMKKMMSLFTLTRNMGNSIGSAI
                     IGYIYAMDVVIFQTSIQNVMVFCIIVLVGLWVVWFTRKDKSLRTVSDK"
     gene            complement(4642..4839)
                     /locus_tag="SPSINT_RS09385"
                     /old_locus_tag="SPSINT_1831"
     CDS             complement(4642..4839)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729476.1"
                     /locus_tag="SPSINT_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1831"
                     /product="hypothetical protein"
                     /protein_id="WP_015729476.1"
                     /transl_table=11
                     /translation="MKPHYKRFMFALMVLWLFQVYFAYDYLLGDGALTASPFLGLVSLG
                     LGILIVIIMISVHRQHKKNM"
     gene            complement(4852..5532)
                     /locus_tag="SPSINT_RS09390"
                     /old_locus_tag="SPSINT_1832"
     CDS             complement(4852..5532)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047256.1"
                     /locus_tag="SPSINT_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1832"
                     /product="hemolysin III family protein"
                     /protein_id="WP_015729477.1"
                     /transl_table=11
                     /translation="MAKSATKKKTTLETFKEMSPLSFGEEVGNSVSHGVAAFIMLLTLP
                     YAAVYSYAHHGVLMSASVSVFVISIFLMFISSTVYHTMQQASPHKYVMRIIDHSMIYVA
                     ITGTYTPVSLVLVGGWLGWSIMIILWGTTIWGILYKAIATKVNPKLSLMIYLIMGWVGV
                     IYLPIIISQSKWLFFIFILLGGLAYTIGAWFYAQKNRPYFHMIWHIFILIASLFHFIGI
                     LYFM"
     gene            complement(5543..6733)
                     /locus_tag="SPSINT_RS09395"
                     /old_locus_tag="SPSINT_1833"
     CDS             complement(5543..6733)
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0070569 - uridylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613279.1"
                     /locus_tag="SPSINT_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1833"
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /protein_id="WP_015729478.1"
                     /transl_table=11
                     /translation="MLESHKLEKYNQSHLTEYEKLMSTNEKERLNDKIAQLDLAEIQSL
                     YQQVYVNRQTIDDVSDVQEVNYETTAHMTDETIEFYRQLGLQAIQEGQFAVLLMAGGQG
                     TRLGYKGPKGSFEIEGVSLFELQARQLKALKEKTGHFVDWYIMTSEINDEATRAFFQEH
                     NHFGYNAEHIYFFKQDNIVALNEQGQLILDKNGSIMETPNGNGGIFKSLKKAGYLDQMA
                     ERHNEYIFVNNIDNVLVKVLDPLFAGFTVHHHKDVTSKSIAPLVGEKVGRLAVRSGKDT
                     VLEYSELDPEVANQFNNANIGIHAFRRTFIKNAVDKSLPYHLAIKELEQLDEDFGVVKK
                     PTLKFELFYFDIFQYATSFVTLQVARDEEFSPLKNKEGQDSIETATNDLKRMNIIE"
     gene            complement(6806..7312)
                     /locus_tag="SPSINT_RS09400"
                     /old_locus_tag="SPSINT_1834"
     CDS             complement(6806..7312)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613278.1"
                     /locus_tag="SPSINT_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1834"
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_015729479.1"
                     /transl_table=11
                     /translation="MTGKTHSAAGILIGAAVGIHFQLDIFEMATCIVVSGLASIFPDIC
                     HTRSKIGQRLPIISLIIKHLFGHRTFTHSLLFMLVVYYALHMIETPIYYMIGIICGMLS
                     HVILDMLTPRGVHLFFPIPIRIRFPIHFKTGGTIDLSLATTFSFVTLYLLFESTMKQIL
                     NYFLQ"
     misc_feature    7366..7379
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.29"
                     /tool="antismash"
     gene            7502..7762
                     /locus_tag="SPSINT_RS09405"
                     /old_locus_tag="SPSINT_1835"
     CDS             7502..7762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017722958.1"
                     /locus_tag="SPSINT_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1835"
                     /product="hypothetical protein"
                     /protein_id="WP_014613277.1"
                     /transl_table=11
                     /translation="MAMTVKKNEEEIHIQWRVADIHIPNDEILNVSEDQDIHAVPEVDA
                     KKVYRIGSTFGKTNRVIIDTNKQQYIIYTFNDKKVYNEVTK"
     gene            complement(8243..9613)
                     /locus_tag="SPSINT_RS09410"
                     /old_locus_tag="SPSINT_1836"
     CDS             complement(8243..9613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613276.1"
                     /locus_tag="SPSINT_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1836"
                     /product="YjiH family protein"
                     /protein_id="WP_015729480.1"
                     /transl_table=11
                     /translation="MEDLNQKEKNTGRLKFIVLSLIGIVLFLIPLPVIEDGKRTTTLPI
                     AFLAKQFQAILGSAIPWIIMLIIIVSGILTILCSTVLKHRIPKNSFRANAFIVTWPWFV
                     IRMLAIIIVCMTFLNKGFSWVYSEDTGGLIFTGLLPTLVAVFFFAAIFLPLLLEYGLLE
                     FLGPIFRPVMRPLFTLPGRSTVDNLASFIGDGTVGVMITSKQYDEGYYTRREATVIATT
                     FSVVSLTFAIVIAETIGLIHRFALFYGTVVLACFIAALIMPRIWPLRYVEDRYSDGATA
                     EERPEKQYSYKESFRRGYEDALSTAYRAPGFKQYMVTAFKTVMDMWLVVIPVVMTVGTL
                     ATILATYTPIFTWIGLPFVPLLELLQVPEAQAASETMIIGFADMFLPSILIESVENPMT
                     QFIVGVLSVCQLIYLSEVGGVILGSKIPVGLGKLFAIFLIRTLITLPIIVLVAHLFF"
     gene            complement(9734..10696)
                     /locus_tag="SPSINT_RS09415"
                     /old_locus_tag="SPSINT_1837"
     CDS             complement(9734..10696)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613275.1"
                     /locus_tag="SPSINT_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1837"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_015729481.1"
                     /transl_table=11
                     /translation="MNIHFGRRYSLIIVLLIVGAILSLSAGAVWISPITVMKEVWSGDN
                     FILSEFRVPRMLLAILVGAALAISGAVIQGVIRNPLASPDVIGITKGASLAAVIVIIVF
                     PTAPLFVLPVASFIGALVISLILSLLISWQGIKGSQLALIGMAIGAVAMALVQYLLIRN
                     PMEANIALVWLTGSLFGRSMDHVLTILPWLIVAIPVIFLYARKLDILHLGEEVATALGT
                     HVQRTKMILLFTSVMLAGAAISAVGGLSFLGLIAPHIARSLVGHQHRHIVAMSGLVGAL
                     LMVIADGLARIIAPPIDIPVGVLIAIIGAPYFLYVLRKM"
     gene            complement(10693..11718)
                     /locus_tag="SPSINT_RS09420"
                     /old_locus_tag="SPSINT_1838"
     CDS             complement(10693..11718)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019165080.1"
                     /locus_tag="SPSINT_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1838"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_015729482.1"
                     /transl_table=11
                     /translation="MSKLNTKLNDEHHQRKRTTLTFIVSVCFLIFAVYLNLAIGSSKIS
                     FQSMLDYFFHLKTTKATFLIHNVRMPRMIAAAMIGAALAVAGVLMQAITRNPLASPQIF
                     GVNAGASFTVVLITVFLPALADNTVVFAFVGAFIGGFTVYTLADTTKGMTPVRLALAGM
                     TIHLFFTSLTQGIILLNEDATTTVMFWLVGALHTIKWPQIFQVLPWIIGGLIAALLLGR
                     QLAILNLGDQLATGLGQNTKRIRALAGLLVIILAGASVSIAGPIGFVGLIVPHIVKHYL
                     NRNYFLIITLSMIMGANLLLISDVISRLIAFPFESPVGIVTSFVGALYFLWITMRGVKA
                     R"
     misc_feature    complement(11706..11723)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.4"
                     /tool="antismash"
     gene            complement(11862..12806)
                     /locus_tag="SPSINT_RS09425"
                     /old_locus_tag="SPSINT_1839"
     CDS             complement(11862..12806)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019168333.1"
                     /locus_tag="SPSINT_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1839"
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_193594672.1"
                     /transl_table=11
                     /translation="MIIVAACGNVSDTDKSKEKSEGTKSVEIKHDGGTTKIDKEPKRVV
                     ALEYSFVDALVALGVKPVGIADDGKKSNLIDPLRDKVGDYKSVGARKQPNLEVISELKP
                     DLIIADNNRHKGNYEQLSKIAPTILLPSLDSDYKDNIEAFKTIAKALSKEDQADKRLKE
                     HEEKIDKYTKQVTMDKDKKVLPVVISQSGLLAHSDKSYVGQFLRDLGFKEALTKEVANQ
                     LPEYLNAPYLNMNSEQLAEVNPERMFIMVNGENDPYYAKMKKDPVWSQIEAVKNNRVHV
                     VDRQTWAKSRGLISSEEIAKELVEISKKESNDK"
     misc_feature    12901..12919
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.02"
                     /tool="antismash"
     misc_feature    complement(12904..12919)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.41"
                     /tool="antismash"
     gene            complement(12921..13997)
                     /locus_tag="SPSINT_RS09430"
                     /old_locus_tag="SPSINT_1840"
     CDS             complement(12921..13997)
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613272.1"
                     /locus_tag="SPSINT_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1840"
                     /product="alanine racemase"
                     /protein_id="WP_015729484.1"
                     /transl_table=11
                     /translation="MPQIHINLSKIKYNAMVLQHMLAEQGIRMIPVTKCMGGDPKVRQQ
                     FREMGFNTLAESRLTAMMTNEQHPTEHDMMIKGALPNEIHDVVRYSQISIQTELETIRA
                     LSDEAVAQGVKHHIYLMVDWKDGREGALTYEVVPLIKEIIRLKGVYLKGLSFNFMCFRQ
                     IPPTEEDIVYINYFIESVERDTGVKFKTISGGNSSMLTLAMYADLGRINELRIGEALFR
                     GYETAYNMRLPYLFDNAVTLSGRILEIKPRLNLETRQSYMQALVDIGQLDTVIAGIQPV
                     DHQLKIVGHSSDTLMMNLGLADYYQLGDKIEFHLDYSALAHSMHMQHIPRSYEEDLGIE
                     QLVRGFVDIKKNNFIKQY"
     gene            complement(14001..15764)
                     /locus_tag="SPSINT_RS09435"
                     /old_locus_tag="SPSINT_1841"
     CDS             complement(14001..15764)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613271.1"
                     /locus_tag="SPSINT_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1841"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_015729485.1"
                     /sec_met_domain="IucA_IucC (E-value: 4.1e-49, bitscore:
                     164.5, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTHKLNADQNIQYRILIACMKEQLFPEKTQLQFKQNQVMIQYH
                     QHVLAVQYETISTLYQLELSGPIVYRVGTEDVTIETVEQLIEILGTHFGITFHDQLVEE
                     LLHSRLGLELSYQQLRQRERVMRHSLKFSRMPDTLNFIAWLNHMNGDELFSVLGYTEGM
                     VWEGHPSHPLTKTKLPLNAEEIQQYAPEFMKIIPLKMVLVRKALLKSTTMTGEEDFVLR
                     KMFPDKESQLRQWMQTYEGTLDDYRIILVHPWQYTNVITTRFKTMIAQHDVIPTPFTVD
                     SKATLSFRTMRLLHYPYHVKLPVNVQATSAVRTISTVTTVDGPKLSYQLQDMLDIYPTL
                     TVASEPYGAHIDVEADLARQFAMIVRHSPEVHTHDYTQLVTAVLTQVNPVDGQVVVDSL
                     IEYLYGDMNGETIQQFMRQYMEALIPPLIAYIQQYGIALEAHQQNTILQMDKENETLSF
                     IVRDLGGSRIYPETLKQTVPDFEITNDSLVSDKIEAVIAKFQHAVIQNQLGTLIHHFHH
                     KHQIDEATLYTIAAAEIEASIDPTRPHADALKRILFGEKMTVKALLNMRMEQKVKQYVQ
                     IDIKNPLEREL"
     gene            complement(15748..16932)
                     /locus_tag="SPSINT_RS09440"
                     /old_locus_tag="SPSINT_1842"
     CDS             complement(15748..16932)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613270.1"
                     /locus_tag="SPSINT_RS09440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1842"
                     /product="MFS transporter"
                     /protein_id="WP_015729486.1"
                     /transl_table=11
                     /translation="MAKWFFPSTFLLFLGNWIGQIALNWYAYQLNENPMDLALINFFRL
                     APIFILSLWAGSIADRYRRSTLIKMTVTSSMVITGTLTVCVLFMNDIPMFYLYIYACLR
                     GCMSAIETPVRQAVLPDISERLTVSKAVSYHSFLLNVCRSIGPAVAGFIIAVYDVPIAF
                     VVQTICYALALVSSLPLKLAVVKPVKNKQFSIAVAMQYFKLHLQGRRIFMTSLLIMAMG
                     YSYTTMLPILTDEVYPNSASVFGTAMTVSAIGGILATLTIPYVLQKFSTDNCYYLSSIL
                     FGIALLLLYPLGEIGLFLMIFFVGLFGQFARTTNRIYFQNDVEQESRGKILSVIMMDRG
                     MIPLGAMLLSYFTELIGITTTFLVMGGATTIIAILGFLTNFKMNGGKTVHDTHA"
     misc_feature    16950..16965
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 25.17"
                     /tool="antismash"
     misc_feature    complement(16950..16968)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 26.03"
                     /tool="antismash"
     misc_feature    complement(16952..16966)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.7"
                     /tool="antismash"
     misc_feature    complement(16953..16968)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: strong, score: 28.84"
                     /tool="antismash"
     gene            17033..19000
                     /locus_tag="SPSINT_RS09445"
                     /old_locus_tag="SPSINT_1843"
     CDS             17033..19000
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015729487.1"
                     /locus_tag="SPSINT_RS09445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1843"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_015729487.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.6e-58, bitscore:
                     195.4, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTEQNHLSMMEKDFTKDEMENYQAVLQFDSNWATQFKRHVLVGR
                     DKITARLMASLYRENLVGSYTHSTFIQAEQLAHSAIPSGQLLMIHFTYGQLTLYARVIS
                     HHAFNRVDVTGPFYWRTADGEDRRVLHPNEVLDVIINEDTRYQGAAAEQFRDDMENSAA
                     HMALALSYQAQHPLKDAPSLLDYIEAQDDPYLTSEQLVVEGHPLHPGAKLRKGMSAQET
                     IDYSSEYQHTMLMQFILVHHDVARTMAQHGTYEEAVYHAFDGLKSVALQAIGSDAPLED
                     YMPLIVHPWQYEHIIRTEYQHELDTKAIIPLDYTKSYYAGLSFRTLMPKKPDVSPHIKL
                     STNVHITGEIRTLSEQTTHNGPLMTNILTDISARDALFNNVSTSPVPEIAGAHFYQPKD
                     RHPDEQERRSEQLGTLFRQNIYDMIDSERLPVIPSSLVVTHPETARPLIVELVERFRQT
                     NDTTTDIDVRAQWFKTYAASLIDYVVPLLVKYGIALEAHLQNTIAVFEPSTGAFSHMLI
                     RDFEGLRIDAEQLAQMGYDTSHFHEKSRILTKSQTSVFNKAFYSTIQNHLGELVAVLSR
                     FYDDVALENTLWSIVRQQIKQCFDKLEAADINPERLAHMQNVFFNEKIDYKCVTTMRLM
                     DEAHEYTYIKVDNPLSKSLI"
     gene            19112..20257
                     /locus_tag="SPSINT_RS09450"
                     /old_locus_tag="SPSINT_1844"
     CDS             19112..20257
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613268.1"
                     /locus_tag="SPSINT_RS09450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1844"
                     /product="MFS transporter"
                     /protein_id="WP_014613268.1"
                     /transl_table=11
                     /translation="MTIMRTLTFMLSIFIVGMVEMVVAGIMNLMSADLNISEAWIGQLV
                     TIYAFTFALTGPILVKLTEKYSPKSVLLSAIAFFVIGNLMIALSPNFTILIIGRIISSA
                     AAALIVVKILSTTVVLARPENRGKMLGIVYTGFSASNVFGVPIGTLIGDWAGWRFTFGL
                     IILVGLIAGVLLTIYLPKEVKSSLQPTQNHTSRILDKGEVTKLLSITFILLTANSVAYI
                     YINPLILSGGHNIQFVSLALLIIGIAGMLGTSMGGFFTDKLSFKTWLLVSGGAFVIVML
                     VLNQLWTASTILLIALFIWHIIQWSTNPAVQSGLIDQVEGDNSQVMSWNMSALNAGIGF
                     GALLGGLIVSHIDLHATIYFAAGIGFIGFIIIVMLKKKRVA"
     gene            complement(20329..20820)
                     /locus_tag="SPSINT_RS09455"
                     /old_locus_tag="SPSINT_1845"
     CDS             complement(20329..20820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500909.1"
                     /locus_tag="SPSINT_RS09455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1845"
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_014613267.1"
                     /transl_table=11
                     /translation="MTVENNKVKESYNRETGVNEKERQQREDNQGQQFSNSLTFSDEVV
                     EKIAGIAAREVRGILDMKGGFVDSISGSFSGGNNVTQGVSAEVGEKQAAIDLKVILEYG
                     ESAPKIFRKVTELIKEQVKHITGLDVVEVNMQVDDVMTRKEWQQKHEKNKDQNENKGLQ
                     "
     gene            complement(20874..21119)
                     /locus_tag="SPSINT_RS09460"
                     /old_locus_tag="SPSINT_1846"
     CDS             complement(20874..21119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016426388.1"
                     /locus_tag="SPSINT_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1846"
                     /product="DUF2273 domain-containing protein"
                     /protein_id="WP_015729488.1"
                     /transl_table=11
                     /translation="MSNENRNGQSERDSVEQFAKLLQSYKWRIIGFFFFLIIAILFLTL
                     GFWKTILIIVLCLIGIGVGYIKDRTQDFLNLLNRLS"
     gene            complement(21132..21674)
                     /gene="amaP"
                     /locus_tag="SPSINT_RS09465"
                     /old_locus_tag="SPSINT_1847"
     CDS             complement(21132..21674)
                     /codon_start=1
                     /gene="amaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432799.1"
                     /locus_tag="SPSINT_RS09465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1847"
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="WP_041614942.1"
                     /transl_table=11
                     /translation="MTRIKNFILGLLIVIIVGFLLFMYIDYQPIKEYQDYFYQFNWFQP
                     LLIGLAGLLILIGLILFLRAFKPTYRKPGLYKDYSDGHIYISRKSIENTVYDTLSKYDE
                     VRQPNVVSKLYNKKKNSFIDITTDFIVPSESANVPSLVEQVRLDIKESVERFSELHVKS
                     VKVNVRDQKRDNGPRVV"
     gene            complement(21949..23477)
                     /locus_tag="SPSINT_RS09470"
                     /old_locus_tag="SPSINT_1848"
                     /pseudo=""
     CDS             complement(21949..23477)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0071705 - nitrogen compound transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500912.1"
                     /locus_tag="SPSINT_RS09470"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1848"
                     /product="BCCT family transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKQTKKKKHVSLVFWISLLLCSLFVLVGAIFPKQMEETTQSITTW
                     IGQNFSWYYLLLLLAIFLICVYLLFSRYSQITLGEEGEEPEFSLKSWFAMLFSAGMGIG
                     LVFWTTAEPISHAYTATPIHQAGTQAAIDDSLQFAFFHWGIHAWAVYAIVALAFAYFNF
                     HKGYPGLVSATLTPLFGEKQMQGPLGKLLDILAVIATVTGVSATLGFGALQISEGLNFL
                     FNIPANFTTQIWIIIMATALFIWSTWSGLSKGIKMLSNINMILAFIVLVVVFIIGPTLF
                     ILNMFTNSLGHYIAHFFDMSLRLTINNPEKSQWIQNWTVFYWAWWISWAPFVGIFIARV
                     SRGRTIKEFIIGVLFVPSLVCFIFFAVFGASAIYLQDNGIANIAGEAIETATFATLEHF
                     PLGFVMSIVTLVVVMIFFVTSADSATYVLGMLSTNGDNYPGSWVKVSWGIMLALFAFIM
                     LLTGGTQAIQNLLIIAALPFSFVIIFMIWSLFKALAAERPRLSKRK"
     gene            complement(23534..24544)
                     /locus_tag="SPSINT_RS09475"
                     /old_locus_tag="SPSINT_1849"
     CDS             complement(23534..24544)
                     /NRPS_PKS="Domain: PKS_ER (20-332). E-value: 1.6e-42.
                     Score: 137.7. Matches aSDomain:
                     nrpspksdomains_SPSINT_RS09475_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220315.1"
                     /locus_tag="SPSINT_RS09475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1849"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_015729491.1"
                     /sec_met_domain="ADH_N (E-value: 4.6e-10, bitscore: 36.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.9e-13, bitscore:
                     47.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAIIATQPFQLAEGQKFEKVSRELPTPEAHDILIKVYATGINPV
                     DTKMRQAPLNAEARVLGFDAAGVVEAVGDAVTDFKPGDRVYYSGSNQRDGSNQTYQLVN
                     ENYLAHMPKTLSFAEAAALPLTAITAYETLFDVFNISPNPQQNQGKTLFIINGAGGVGS
                     IATQIAKTYGLTVVTTASRPETNAWSKKMGADVVLNHKEDLAKQFDDQNLSRPNYIFCT
                     YDTDHYYDVMIDLVQPRGHIATIVAFNKNQDLNALKQKSITFTHEFMFARAIHGVDEGM
                     YRKYLEDVTAKVDADQYQTTLNSVFTGLTPENVLKAHEMMEAQSHIGKLVIEIVE"
     aSDomain        complement(23549..24484)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SPSINT_RS09475_PKS_ER.1"
                     /evalue="1.60E-42"
                     /label="SPSINT_RS09475_PKS_ER.1"
                     /locus_tag="SPSINT_RS09475"
                     /protein_end="332"
                     /protein_start="20"
                     /score="137.7"
                     /tool="antismash"
                     /translation="VSRELPTPEAHDILIKVYATGINPVDTKMRQAPLNAEARVLGFDA
                     AGVVEAVGDAVTDFKPGDRVYYSGSNQRDGSNQTYQLVNENYLAHMPKTLSFAEAAALP
                     LTAITAYETLFDVFNISPNPQQNQGKTLFIINGAGGVGSIATQIAKTYGLTVVTTASRP
                     ETNAWSKKMGADVVLNHKEDLAKQFDDQNLSRPNYIFCTYDTDHYYDVMIDLVQPRGHI
                     ATIVAFNKNQDLNALKQKSITFTHEFMFARAIHGVDEGMYRKYLEDVTAKVDADQYQTT
                     LNSVFTGLTPENVLKAHEMMEAQSHIGKLVI"
     CDS_motif       complement(24326..24364)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SPSINT_RS09475_0001"
                     /evalue="2.10E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="SPSINT_RS09475"
                     /protein_end="73"
                     /protein_start="60"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LGFDAAGVVEAVG"
     gene            24646..25635
                     /locus_tag="SPSINT_RS09480"
                     /old_locus_tag="SPSINT_1850"
     CDS             24646..25635
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016426383.1"
                     /locus_tag="SPSINT_RS09480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1850"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_015729492.1"
                     /transl_table=11
                     /translation="MLLSILDYSPIFEDRTPQDALNHSVDLARYAENLNFHRYWLAEHH
                     EVHSVASTAPEILATMILEQTSRIHVGAGGIMLPHYSPYKVAETFKMLEARHPGRVDIA
                     LGKSPSFQNVSQALNEDKQTLTDFDQQLMDLTKYFNNDSSTPHRFQHLKAMPVIETQPQ
                     FCILGTSENSAERAAQLGAVFVFGAFGQKTIEKQRIIQRYRKQFQHYHPEGQPYLIVST
                     FVLAHENSQIRAQLEDSLHYWLQRIHYLKQPKTLLSPETIQQKNWSVRELEKRAENAPR
                     IISGDGETVAHELHELQRTFDADELLLFPQLYGEENRKHCLALIAKYW"
     gene            complement(25796..27430)
                     /locus_tag="SPSINT_RS09485"
                     /old_locus_tag="SPSINT_1851"
     CDS             complement(25796..27430)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498689.1"
                     /locus_tag="SPSINT_RS09485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1851"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_015729493.1"
                     /transl_table=11
                     /translation="MNIVNVSQLTKSYNGNKVFDHIKFEVNQNDRIGLIGRNGEGKTTL
                     FKLIAKKEQADEGFISIAKDVKVGLLAQIPNLPPDAIVINQLYQAFDTLNGIEQRMRQL
                     EIKMVEGADDINQILKQYDRLQNEFETLGGYDRDYKIDIVLNGLKIAHLKTQQWSNLSG
                     GMQTKVGLAMLLLQSPELLLLDEPTNHLDIESIEWLTKFIQQYKGAVMVISHDRYFLDE
                     TVTQILEIDQQQLYVYPGHYSNFVIEKEKRILNEFKAYQTQQKKIQKMKAQIKQLKIWA
                     NQAKPPNASMHRRAKSMEKALARIEVKPKPRLAYNKMKLDIAQSESASKDIFVLKDVAK
                     MYDDILFEGVNMKIRRRDKVAIVGANGTGKSTLLKLLLREIVPDEGHVQIAETNRIGYL
                     AQHQFNTGEMSVLEAFRQYAHVSEGEARNHLAKYLFYGYDVYKKVKDLSGGEKMRLRWA
                     QMISQQFNVLILDEPTNHLDIDAKEALEEALEDFDGTVIAVSHDRYFLDKHFSKTYWID
                     NKQLHYYPGHYSYAKQKRYSEARQKTN"
     misc_feature    complement(27401..27416)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    27516..27529
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.07"
                     /tool="antismash"
     misc_feature    27643..27658
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            complement(27893..29299)
                     /gene="lacG"
                     /locus_tag="SPSINT_RS09490"
                     /old_locus_tag="SPSINT_1853"
     CDS             complement(27893..29299)
                     /EC_number="3.2.1.85"
                     /GO_component="GO:0009341 - beta-galactosidase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004565 - beta-galactosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lacG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613258.1"
                     /locus_tag="SPSINT_RS09490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1853"
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="WP_015729495.1"
                     /transl_table=11
                     /translation="MKKLPEDFIFGGATAAYQAEGATNIDGKGRVAWDTYLEKNYWYTA
                     EPASDFYHRYPVDLELSEKFGVNGIRISIAWSRIFPKGYGEVNPKGVDYYHRLFKECMK
                     RNVEPFVTLHHFDTPEALHSNGDFLNRENIQHFVEYAEFCFNEFKEVNYWTTFNEIGPI
                     GDGQYLVGKFPPGIQYHFEKVFQSHHNMMVAHAKAVALFKEQGHQGEIGVVHALPTKYP
                     FNPDDPEDVRAAELEDIIHNKFILDATYLGHYSKETMDGVNHILSINGGALDLRPEDFE
                     ILEVAKDLNDFLGINYYMSDWMRSFEGESEITHNSKGDKGGSKYQLKGIGQREFDVDVP
                     RTDWDWMIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFINDTVQDDARIDYVKQ
                     HLEVIADAIEDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQQRYPKKSAYWYK
                     KLAETRIIES"
     gene            complement(29317..31041)
                     /locus_tag="SPSINT_RS09495"
                     /old_locus_tag="SPSINT_1854"
     CDS             complement(29317..31041)
                     /EC_number="2.7.1.207"
                     /GO_component="GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA]"
                     /GO_function="GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613257.1"
                     /locus_tag="SPSINT_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1854"
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="WP_015729496.1"
                     /transl_table=11
                     /translation="MNKLIGFIEKGKPFFEKLSRNIYLRAIRDGFISAMPIILFSSIFL
                     LIAYVPNIFDFKWSKETEALIMKPYHYSMGIVGLFVAGTTAKALTDSYNRKLERTNQIN
                     FISTMLASMSGFLFLASNTLEAGGFANAFMGTKGLLTAFLSAFITVMIYNICIKNNITI
                     KMPKEVPPNISQVFKDLIPFSLVILTLYGLDILSRSVNKTNVAESILKVFEPLFTAADG
                     YVGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANIETNFKLLHAGEHADKILTPGTQ
                     MFIVTMGGTGATLVVPFIFMWLSKSKRNKAIGRASVVPTFFGVNEPILFGAPIVLNPIF
                     FIPFIMAPIINVWIFKFFVDVIGMNSFSVFLPWTTPGPLGIVMGTGFGVWSFVLAMTLI
                     VVDTFIYYPFFKVYDNQILDDELKGIDSTNELHAKVGENFNTSKADAILNASTNQSVAD
                     MTQEANSSNPITKPINVLVLCAGGGTSGLLANALNQAATEYEAPVKAAADSYGAHMDIM
                     KDFDLVILAPQVASNYQDIKQDTDRLGIKLAKTQGGEYISLTRDGQAALKFVQDHFR"
     gene            complement(31047..31361)
                     /locus_tag="SPSINT_RS09500"
                     /old_locus_tag="SPSINT_1855"
     CDS             complement(31047..31361)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263056.1"
                     /locus_tag="SPSINT_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1855"
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="WP_014613256.1"
                     /transl_table=11
                     /translation="MNREEVAMLGFEIVAYAGDARSKYLEALSAAQVGDYDKAEQLIEE
                     GNQCIVDAHKAQTSLLQKEAMGDDIAYSVTMMHGQDHLMTTILLKDMLKHIIELYKRGS
                     "
     gene            complement(31387..32355)
                     /gene="lacD"
                     /locus_tag="SPSINT_RS09505"
                     /old_locus_tag="SPSINT_1856"
     CDS             complement(31387..32355)
                     /EC_number="4.1.2.40"
                     /GO_function="GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /gene="lacD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019835810.1"
                     /locus_tag="SPSINT_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1856"
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="WP_015729497.1"
                     /transl_table=11
                     /translation="MSNKQELLARLSDENGIISALAFDQRGALKRMMAQFQASEPEVRD
                     IEQLKKLVSEELTPYASSILLDPEYGLPATQVRHSSTGLLLAYEKTGYDVNAKGRLPDC
                     LVDWSAKRIKEAGAQAVKFLLYYDVDDEAYINDQKEAYIERIGSECKAEEIPFFLEILA
                     YDDSIKDNKSKEYAKVKPRKVIEAMRVFSNERFGVDVLKVEVPVDMNYVEGFSQGEFVY
                     TREEAAAYFKQQDEATHLPYIYLSAGVSAQLFQETLKFAHEAGAQFNGVLCGRATWSGA
                     VKAYIENGEEAAREWLRTEGYHNINELNHVLKETAVSYKSK"
     gene            complement(32426..32941)
                     /gene="lacB"
                     /locus_tag="SPSINT_RS09510"
                     /old_locus_tag="SPSINT_1857"
     CDS             complement(32426..32941)
                     /EC_number="5.3.1.26"
                     /GO_function="GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /gene="lacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500921.1"
                     /locus_tag="SPSINT_RS09510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_1857"
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="WP_014613254.1"
                     /transl_table=11
                     /translation="MKIAIGSDHIVTDTKMEVSQFLKSLGHEVLDCGTYDFARTHYPIF
                     GKKVGEAVTSGEADLGICICGTGVGINNAVNKVPGVRSALVRDMSSAIYAKEELNANVI
                     GFGGKIIGELLLCDIVEAFINAEYHPTAENKRLIEKIAQVESENENQKEDSFFDEFLEK
                     WDNGEYHD"
ORIGIN
        1 gactgcgact gttgatttcc caacgccacc tttacctgaa gcaatggcaa taaattctaa
       61 atgattccct ttcgctagcg caccttcaat ggtttgttct tcttgttgtt gcgtccctgc
      121 atattgtttt accttttctt caggaagggt ttcaaaacga atgcctactg tcttcgcacc
      181 attttctttt agtttctcca caatcgccat ttgtaattca agttgtggct gtcctcccaa
      241 ttgagccatt gcaactttga cgctaacatg tgctttttct tctttgatgg tcacctctac
      301 aaccccttca gtttctttaa gaggtacatt aattattgga tcgttaattt ctccaataag
      361 ttgtttcacc tgttcgactg ttaacacttc cgacatctcc ttttgtatac gctttattcc
      421 tcattttaac aaacttttac actgttgcat aaggtaaaaa ctccacctat ccataaaaat
      481 tgcgtctctc actcatcagt tcaagctttt tacaaataca aatgtttagt catactcatt
      541 gtctttattt tagttcgctt tctcatcata atttttgctt cattttgaat atgaaatcta
      601 atatgttcaa tgtttattaa ttcactcagc cttcatacat gcataaaaaa acatcaaaca
      661 acgtcatgct gtttgatgtt tcatctttca tcttttatca tcacattatc gtacgacgtg
      721 gcgttgatga ccacgttcct ttttccctct atcgtgaata aagaaactga gaataaaccc
      781 gattaataag aagcctgaag taacgtaaaa tgctagatcg acaccgtgtg ccattgcttc
      841 acgttgaatc attgtttttg atacagacgc atctggttga taaagtcctg ctcctaagct
      901 cattaatgta accatcagcg ccgtgcccat agatcctgaa attgttcgta acgtattcat
      961 gattgctgta ccatgtgaca ccatatcatt tggtaatgcg ttaattccag ctgtgttgag
     1021 cggcatcatc aataacgaca ctgagaataa acgaatcgta aagatgataa tcacatacgt
     1081 ataagatgta tgtgctgtca attgagccat catcaatgtc gtaatcaaga gtaatgcaaa
     1141 tcctggaatg acaagtactc tcgcacctac tttatcatat aaacgaccgt tcacgaccga
     1201 catgacaccg ttaatgaccg caccaggtaa tacaacaagt cctgatagta acgctgatag
     1261 accgagtgaa ttttgaatat aaattggaat taacaacgct ggaccaacca ttgacgtaaa
     1321 gacaatcata gatgaaatgg acgttaatgt gaatgttctt gtacgaaaag cagataatct
     1381 gagtatgggg ttgtcaatac gtaattgacg ggtaataaat aaagccacaa tagcaatacc
     1441 aacaatcaaa cttatcaata cgattaaatc atcgaaccca cgcgtacctg caatactaaa
     1501 gccgtacaac ataataccga aaccaagtgt cgagaggaca acagatgctt tatcaagaac
     1561 aacttctttt gtatcactaa agttacgcat ataacgccaa ccgaaaatca agccgataat
     1621 tgaaacaact accacaacga ataacggtga acgccatgaa taattgtcaa cgagtacccc
     1681 cgacaatgta ggtccaatgg ctggagcgaa ctgaatgaca agccctgata atcccattgc
     1741 aaatccacgt tgatttttgg gaaataacgt aaatagcgta aactgactga gcggcataat
     1801 cacacctgca cccaacgctt gaatgacacg tgcagtcatc aatattgaga atgacggcgc
     1861 taacgcagca gtgatagaac caacaacaaa agtccccatc gctgttaaat acaacgttct
     1921 tgtaggtact ctatccatta aataggccgt taatggaatc ataataccat tcactagcat
     1981 aaatcctgta actaaccatt gagaagtgct ttcatgaatg tccagacctc tcataatact
     2041 aggaagtgca gtattcaata atgtttggtt taaaattgca ataaaggcac tgatcaaaat
     2101 aacagcaacg atgatatttc tttgtgtttt atctacatga acacctttat gcatacactt
     2161 tcctcctctt acatttctat accaatgctt tattttacga ctaaaaagtt agcttggcaa
     2221 agtttttgat ttctctttaa aagcccgcca tgacaactct tattttcgat tcaaatcctc
     2281 agcatctgga taaaatactt ctttacaaat gtagagaaac gcaatgatta acatcaacac
     2341 ccaatagtcg atttgaatat attgataatg aatatgaatc acaaaataaa acattgtaat
     2401 catcatcgca tacgaaatca aatgaaatgt gaaaccttcg aggtaagggt tcggatataa
     2461 tttcttttgg agccagtcca tcaaatactc gacaccaaaa atcacaaagt aaccgaggat
     2521 aatatagctg ccgtaataaa ttaaattgtc ataaaatcct tcattataag taaacatgcc
     2581 aaggcgaaag tagatcagta agcgacttaa gccgaataag ccaaaaccga gtaacgttaa
     2641 aaagatcgcc ccagaaatga caaaaatgga gaggatgatt aacaaagcga caaagttaaa
     2701 caaattaaac ttacctttca ccaatcaaac ctccccatat ctttaattat ttatcagaaa
     2761 ctgtacgtaa acttttatct ttacgtgtaa accaaactac ccacaaccct actaatacta
     2821 tgatacaaaa taccataaca ttttggatgc tcgtttgaaa gataaccaca tccatcgcat
     2881 aaatgtatcc aataattgct gatccaatcg aattccccat attacgagtc agtgtaaaga
     2941 gcgacatcat ctttttcata ctttctggaa atgtttcttc ttgtaccatc acactatctt
     3001 tcgtataagc cgtcccaaag ctcataccca aaaagaacaa tgtcatagca acaacgatag
     3061 gataaaatgc accaatcaat acactgatac ttcctacaat taaaatacct attgcgagta
     3121 gatataaacc tcgaacagta cgattcgctt caattatttc taaagtgaag ttaatcaaca
     3181 accagccgat tgacagtggg aaaatgataa gtccactttg caacggggtt aaacctaaat
     3241 gatcttgtaa ataagatgga ataaaaacat taaagccaat taacgttact gcaatgaaaa
     3301 aatcagtaaa aaatgctaaa cgtactttag agtcaaattc tttcgttgga ataaaggaca
     3361 atgacacttt tttcgaacgc ttgattgtga cgccaaaaaa gatgacaaat aaaactaagc
     3421 aaacaacatt catccaaata tgacctgtga tgagcacact cgccatgagt aatgctagta
     3481 acacataaaa taggcccatg ccgacaaaat caactttatg tttagacgtt gattcacttt
     3541 caaaatgata tgaagttaac acaagcagca tcacgatgac agcaatagga atattaatgt
     3601 aaaatagcca atgccatgaa gaaacttcta aaataaagcc accgagaaat ggcccgagaa
     3661 tactcgagat gccccagaca ctgccgacaa tccccatcac tttataacga aatggaatct
     3721 caaatgcgag tttcgggacg atttgtacta atgacatgtt taccccagcg ccgacacctt
     3781 gaagtaagcg ggcaaacacg agcatttcaa aatgggaact catccctgat aaaaaactac
     3841 cgactaaaaa taaaattagt cctaacatcg tcacatagat gattttaatc cgtgacatta
     3901 attcacttaa aataggaata gataacacaa tccctacaaa atacactgta aacacgagtg
     3961 aaatgggctg tgttgcatgt agatcagcac gcatcgtcgg taacgctaac gacacaatcg
     4021 acgtttcgat agctgccata aacatggtta agactagtga gcaaataata ctaacttgct
     4081 ttaaattcat acttttctac ctttccataa aatatttatt attgcagaca taaggtttgt
     4141 gaagtaaacc tatcttaaca tcgcaattaa tcacctttgc cctattaaaa agttcaactc
     4201 agctgaaaat gaaaaaatgc tttcaaacgt tctcatcttt taatacagag accgttcaca
     4261 tcaatctgaa gcgtaagact cacacattcg tccatcacag cacattggac gaataattaa
     4321 caccttgctt ttatgtaaag tttaaaaccg ttcattttca ttatctctac ttattgtgaa
     4381 tttgataagc aataaaatca aactttatgt attaaagaaa gcgataaact ccatttttgt
     4441 atcccattca ctctcacttt ccaactgttt tttaatcatt aatgaatcat aagtctatga
     4501 atagattaag gttaaaatct atcgatgtcc cttttcttaa aacatcattt actatctata
     4561 aaagacaaga gactgttata gtgtcatcaa tcctcgctac acgaacgatt gatgtctcga
     4621 aacagtctct ttatatgatg attacatatt ctttttatgt tgccgatgta cagaaatcat
     4681 gataatgaca atgaggatac ctaagcctaa tgataccaaa cctaggaatg gcgatgctgt
     4741 taacgcccca tctcccaaca agtaatcata tgcgaaatac acttgaaaca gccataaaac
     4801 cattagtgca aacatgaatc gcttataatg cggcttcatc caaacaccca cctacataaa
     4861 atataaaata cctatgaaat gaaataatga agcaatgagt ataaatatat gccagatcat
     4921 atgaaagtat ggtctgtttt tttgtgcgta aaaccatgcc cctatcgtat aagctaaccc
     4981 gcctaataaa atgaaaataa agaatagcca tttggattga ctgatgatga taggtaagta
     5041 aatcacaccg acccatccca taatgagata aatcatcaag ctcaacttag gatttacttt
     5101 cgttgcaatg gctttatata aaatccccca aatggttgtg ccccaaagga taatcataat
     5161 agaccaaccg agccaaccac ctacgagtac aagtgagaca ggcgtatatg taccagtgat
     5221 tgcaacataa atcatactgt gatcaatgat gcgcatcaca tatttatgag gagacgcttg
     5281 ttgcatcgtg tgataaaccg ttgatgaaat gaacatcaaa aaaatactaa tgacaaatac
     5341 agacacactg gcagacatca atacgccgtg atgtgcataa ctgtatacag ccgcataagg
     5401 taaggtcaat aacatgatga atgctgcgac accgtgcgag acgctattac caacttcttc
     5461 tccaaaagac aaagggctca tttctttaaa tgtttctaac gtcgtttttt tctttgtagc
     5521 acttttggcc atatgattac ctctattcaa tgatgttcat acgcttcaaa tcatttgttg
     5581 cagtttcgat actgtcttga ccttctttat ttttcaacgg actaaattcc tcatctcgag
     5641 caacttgtag tgtcacaaat gaagtagcgt attgaaaaat atcaaaataa aacagttcaa
     5701 actttaatgt cggctttttc acaacaccaa aatcttcatc taattgctca agctctttaa
     5761 tagcaaggtg ataaggaagt gatttgtcta ctgcattttt aataaatgtg cggcgaaacg
     5821 catgaatacc gatattggca ttgttaaatt gattcgctac ttcaggatca agctctgaat
     5881 attctaacac tgtgtcttta ccacttcgaa ctgctagacg gcctaccttc tcgcctacaa
     5941 gtggtgcaat agatttagac gtcacatctt tatggtgatg tacagtgaaa ccagcgaata
     6001 atggatccaa cactttgaca agaacattat caatattatt cacgaaaata tactcattat
     6061 gacgttcagc catttgatca aggtaacccg cctttttcaa cgatttgaaa ataccaccat
     6121 taccattcgg tgtttccata atgctaccgt ttttatctaa tatcaattgt ccttgttcat
     6181 ttaacgccac gatattgtct tgtttaaaaa agtaaatatg ttcagcatta taaccgaaat
     6241 gattatgctc ttgaaaaaat gcacgtgtag cctcatcgtt aatttcactt gtcataatgt
     6301 accaatcgac aaaatgacct gttttttctt ttaatgcctt taattggcgt gcttgcaatt
     6361 caaacaagct cacaccttca atttcaaatg aacctttagg ccctttataa cctaaacgtg
     6421 tgccttgacc gcccgccatt aacaatacag cgaattgacc ttcttgaatg gcttgtaaac
     6481 cgagttgccg ataaaattct atcgtttcgt ccgtcatatg tgcagttgtt tcatagttca
     6541 cttcttggac gtctgaaaca tcatcaatcg tttgacggtt cacataaact tgctgataga
     6601 gtgattgaat ttctgctaaa tctagttgag caattttgtc gttcagtcgc tccttctcgt
     6661 tcgtactcat aagcttttca tattctgtta aatgtgattg attatatttt tcaagtttat
     6721 gactttctaa cataataaat tgtacgctcc tttaataaag ctgtgactca atttcattaa
     6781 cacatcactt catataattt aatcactatt gcaaaaagta atttaaaatt tgtttcattg
     6841 tcgactcaaa caacaaatac aatgtgacaa aactaaaagt agtcgcaagt gataaatcta
     6901 tagtaccacc tgttttaaag tgaattggga aacgtatgcg aatcggtatc ggaaaaaata
     6961 aatgtacgcc tctcggtgtt aacatatcta atatcacatg tgaaagcata ccacaaatta
     7021 taccaatcat atagtaaatt ggtgtttcga tcatatgtaa tgcatagtaa accacgagca
     7081 taaagagtaa agaatgtgta aaagtacgat gaccaaacag atgtttgata atcagactga
     7141 tgataggcag ccgttgtcca atcttactcc gcgtatggca aatgtcagga aaaatactcg
     7201 ctaaaccaga tacaacaatg catgtggcca tttcaaaaat atctaattgg aaatgtatgc
     7261 ccactgcagc tccaataaga atacctgcag cagagtgtgt tttgccggtc atgttaacca
     7321 cctttctatt gatgtgtgga ttataccata aaacgcacaa aaacacgaac atattttcgc
     7381 gtattccatc aattctcaaa tagtataaca catttaactt tctgtaactc attttatttg
     7441 aaaaagcggt ttcaatcagt tacaatgaac ctacaaatag aaataaagga tgtgttttgt
     7501 aatggcaatg acagtaaaga aaaatgaaga agaaattcat attcaatgga gagtagcaga
     7561 tattcacatt cctaatgacg aaatcctaaa tgtgagtgaa gatcaagata ttcatgcagt
     7621 acctgaagta gatgcaaaaa aagtttatcg tattggttct acatttggta aaacaaaccg
     7681 tgtgattatc gacacaaaca aacaacaata cattatttat acgtttaatg ataaaaaagt
     7741 atacaatgaa gtgacgaagt aatacttaaa gttatgaaat gggatggctc acgctgtccc
     7801 attttttacg tgtttatatt aataaggcat catacaaaaa ggaaacaagt tgggagttaa
     7861 aaacccgtaa cctgtttcct ttttattagc aacatttatc aatagccaat cattcaataa
     7921 aagcgattgc gtttggtaca aaaatttaat ggggatggga tataaaaaaa ttttgatgct
     7981 attgatgcaa tatgtttgtt gtactagcca tacccataac ttgtggtttg agattgacat
     8041 catggctttc ctaggggttg gtccttcaac gcactgccga aaatccaatt tggcccccac
     8101 catatgaaca ctttaatcga accaaattta gttaagacaa atcccctggg aacgcgaatc
     8161 caaaagggca atcacatcaa taccaataga aaaatttgca aaggttgtgt cctcgcctct
     8221 tttcttttga ttgcgctttg ctttagaaaa ataaatgtgc cactaacaca ataattggta
     8281 acgtaatcaa tgtacggatt aaaaagattg caaaaagttt tcctaatcca actggaattt
     8341 ttgatcctaa aataacgcca ccaacttctg ataaataaat caattgacag acacttaata
     8401 caccgacaat gaattgtgtc attggatttt cgacactttc gattaaaata gatggtaaaa
     8461 acatgtccgc aaagccgata atcattgttt cagaggccgc ttgtgcttct ggtacttgta
     8521 acaactctaa aagcggcaca aatggtaatc caatccatgt gaatatcggt gtgtacgtcg
     8581 ccaaaatagt tgctaatgta ccgacagtca tcacgacagg aatgacgaca agccacatgt
     8641 ccatcaccgt tttaaaggct gtaaccatgt attgtttaaa cccaggcgca cgatatgctg
     8701 tcgacagcgc atcttcataa cctcgacgga atgattcttt gtaactgtat tgcttttctg
     8761 gtctttcttc agctgttgca ccatctgaat aacgatcttc tacatagcgc aaaggccaaa
     8821 ttctaggcat aatgagtgct gcgatgaaac aggctaacac gactgtccca taaaaaagtg
     8881 cgaaacgatg aattaagcca atcgtttctg ctattacaat cgcaaatgtt aatgaaacga
     8941 cactgaacgt cgtcgcaatg actgtagctt ctcgtcgtgt ataatatcct tcatcatatt
     9001 gtttgctcgt aatcatcaca ccgactgtgc catcaccgat aaatgatgcg aggttgtcta
     9061 cagttgaacg tcctggaagt gtaaacaacg gtcgcataac aggtctgaaa atcggaccta
     9121 aaaactctag taaaccgtat tcaagcaata atggtaaaaa gattgccgca aagaagaata
     9181 ctgcgactag cgttgggagt aatcctgtaa aaataaggcc tcccgtatct tctgaatata
     9241 cccatgaaaa tcctttgttt aaaaatgtca tacaaacgat aatgatcgcc agcatccgaa
     9301 tgacaaacca tggccatgtc acaataaatg cattcgctct aaagctattc ttcggtatac
     9361 gatgctttaa aacggtacta cataatatcg tcaaaatccc tgaaacgata ataatcagca
     9421 taatgatcca tggaatcgct gatccgagta tcgcttgaaa ttgttttgct aaaaatgcaa
     9481 taggtaacgt tgtcgtacgt ttcccatctt ctatcacagg gagtggaatt aaaaacagca
     9541 caattccaat gagtgaaaga acaataaatt tcaatctccc tgtatttttt tctttctgat
     9601 tcaaatcttc catttcctcc cgccttctcc ccttagtata agacagttca acaattgata
     9661 taaattatac aaaatctcct atatatatgc aatgttcaat caaacacaaa cgatttaatt
     9721 tcaagtttat ccgttacatt tttcgtaaca cataaaggaa atatggtgca ccaataatcg
     9781 caatcaacac gccgactggt atatcaatag gcggtgcaat gatacgtgcc aaaccatctg
     9841 caataaccat taataatgca cctactaatc ctgacatcgc aacgatatga cggtgttgat
     9901 gaccgacaag acttcttgca atgtgtggcg caatgagtcc taaaaagctt aatccaccga
     9961 ctgcagaaat tgctgcacct gccaacatca cggatgtgaa gagtaaaatc attttcgtgc
    10021 gttgtacatg cgtacccaac gccgtcgcaa cttcttctcc taaatgtaaa atatcgagct
    10081 ttctcgcata taagaaaatg acaggaatcg ctacaatcag ccaaggtaaa atagtcaaca
    10141 catggtccat cgaacgaccg aaaagactgc cggttaacca tacaagtgca atgttggctt
    10201 ccatagggtt acggatgagt aagtattgta ctaacgccat cgcaacagca ccaattgcca
    10261 tcccgatcag cgccagttgt gaacctttaa tcccctgcca actaatcaac agagataaaa
    10321 tgagactgat gactaatgcc ccaataaatg aagcaaccgg gagcacaaat aaaggcgcag
    10381 tcgggaacac aataatgaca ataaccgccg ctaaacttgc ccctttcgta ataccaataa
    10441 catccggtga cgcaagagga tttcgaatga caccttgaat gactgcacct gaaatcgcta
    10501 atgccgctcc gactaatata gcgagtaaca tacgggggac tctaaattca cttaatataa
    10561 agttgtcacc tgaccacact tctttcatta ccgtaatcgg tgaaatccaa accgcacctg
    10621 cacttaaact taaaatggca cctacaataa gaagtacgat gattaaacta taacgtctac
    10681 caaaatgaat attcatcgtg ctttcactcc tctcattgta atccataaga agtataacgc
    10741 gccgacaaag gaggtcacga tgccgactgg tgattcgaat ggaaaggcaa ttaaacggct
    10801 aatgacgtca gatatcaata ataaattagc ccccataatc atagacagtg taatgattaa
    10861 aaaataattc cggttcaaat aatgtttgac gatatgtggc acgatgagac caacgaaacc
    10921 aatagggcct gcaatagaca cactcgcacc tgctaaaatg atgacgagta gcccagctaa
    10981 ggcacgaatg cgtttcgtat tttggccgag acctgttgcc aactgatccc ctagatttaa
    11041 aatcgcaagt tgacgcccaa gtaacaatgc ggcgataagc ccaccaatga tccacggtaa
    11101 aacttggaat atttgtggcc atttaatcgt atgcaacgcg ccgactagcc aaaacatcac
    11161 cgttgtcgtg gcatcttcat ttaacagtat aatgccttgc gttaagcttg tgaaaaataa
    11221 gtggattgtc atcccagcaa gcgctaatct tacgggcgtc atccctttag tcgtatcagc
    11281 aagtgtataa actgtaaaac ctccaataaa tgcaccgaca aaggcaaaca ctacagtatt
    11341 atcagctaat gcaggtagga aaacagtaat gaggacgact gtaaaagaag cacccgcatt
    11401 gacaccgaaa atttgtggtg aagcaagtgg gttacgtgta atcgcttgca ttagtactcc
    11461 tgcaacagcc aatgctgcgc caatcatcgc agctgcaatc attcttggca ttcgtacgtt
    11521 atgtattaaa aatgttgctt ttgttgtttt cagatgaaag aaataatcta acatcgattg
    11581 aaaagaaatt tttgatgaac cgattgcaag atttaaataa actgcaaaaa taagaaagca
    11641 cacgcttaca ataaacgtaa gcgtagtgcg ttttctttgg tgatgttcat catttaattt
    11701 tgtatttaac ttcgacataa caaatcacct tttatataca aagacatgag cttgggatac
    11761 ttacatttta gcgtgttcat ctatcatgca cgtaaactca ctagaatcat acattgaacg
    11821 aactcactta atgtgttaat ttttctatcc ctatcgaact cctacttgtc gttgctttcc
    11881 tttttagaaa tttcaacaag ttcttttgca atttcttctg aagagattaa ccctcttgat
    11941 tttgcccatg tttgacgatc aacaacatgg acgcgattat ttttaaccgc ttcgatttga
    12001 ctccaaactg ggtctttttt cattttagcg taatatggat cattttcgcc attcaccata
    12061 ataaacatac gctcagggtt cacttcagct aattgttctg agttcatatt taagtatggt
    12121 gcgtttaagt attcaggtaa ttgatttgca acttctttag ttaatgcttc tttgaaacca
    12181 aggtcacgta aaaattgacc aacatatgat ttgtcagagt gtgctaaaag acctgattga
    12241 gaaatgacaa ctggtaaaac ttttttgtct ttatccattg taacttgttt cgtgtactta
    12301 tcaatttttt cttcatgttc ttttaatcgt ttgtcagctt gatcttcttt agataatgct
    12361 ttggcgattg ttttgaacgc ttcgatattg tctttgtagt cagaatctag acttggtaat
    12421 aaaatagttg gtgcgatttt acttaattgc tcatagttcc ctttatgacg gttattatcc
    12481 gcaataatta aatcaggttt aagttcactg atgacttcta agttaggttg tttacgtgca
    12541 cctactgatt tgtaatcacc cactttatcg cgaagtggat cgataaggtt tgatttttta
    12601 ccatcatccg cgatccccac tggtttcaca cctaatgcga ctaaagcatc cacaaatgaa
    12661 tattctaaag cgacaactct tttaggctct ttgtcaattt tagttgtgcc accgtcgtgc
    12721 ttaatttcaa cactttttgt accttctgac ttctcttttg acttgtcagt atcacttaca
    12781 ttgccacaag ctgcaacaat gatcattaca gcaattaggg cgacaatccc ccaccatttc
    12841 tttgttttca ctattctgcc actcctttga actatgtttt tcaaatacat tttaataata
    12901 gttgataacg attctcaatg tcaatactgt ttgataaaat tattcttttt gatatcgaca
    12961 aatcccctta ccaattgctc aatgcccaaa tcttcttcat aacttctcgg aatatgttgc
    13021 atatgcatgc tatgtgcgag cgcgctataa tctaagtgga actcaatctt gtcgccaagt
    13081 tgataataat ctgcaagtcc tagattcatc atgagtgtat cgctagagtg accgacaatt
    13141 ttaagctgat gatctacagg ttgaatacca gcaataacgg tgtcgagctg tccaatatcg
    13201 actaaagctt gcatataaga ttgacgtgtt tcaaggttta agcgcggttt aatctctaaa
    13261 atacgcccac ttaatgtcac tgcattatca aataaatacg gcaagcgcat gttataagcc
    13321 gtctcatagc ctctaaatag tgcttcaccg attcgtaatt cattaatacg tccgagatcc
    13381 gcatacattg ctagtgtcaa catgctcgaa ttcccacctg aaatcgtctt gaatttcacg
    13441 cctgtgtctc gttcaactga ttctataaaa taattgatat acacaatatc ttcttcagtc
    13501 ggtggaattt gacggaaaca catgaagtta aatgacagtc cctttaaata gacccctttt
    13561 aagcgaataa tttctttaat gagtggcaca acttcatatg tgagtgcacc ttctcgcccg
    13621 tctttccaat cgaccattaa ataaatatga tgttttacgc cttgtgcaac cgcttcgtca
    13681 ctgagcgcgc gaatcgtctc cagttctgtt tggatgctga tttgactata gcgaacaaca
    13741 tcgtggattt catttggcag tgccccttta atcatcatat cgtgttcagt gggatgttgt
    13801 tcattcgtca tcatcgctgt taaccgtgat tcagccaaag tgttaaaacc catttcacga
    13861 aactgttgac gcactttggg atcgccaccc atacacttcg tcactggaat catacgtatc
    13921 ccttgttctg caagcatgtg ctgtaaaacc atcgcattat atttaatttt actcagatta
    13981 atgtgtattt gaggcataaa ctacagctct ctttctaaag gattttttat gtctatttgc
    14041 acgtattgtt ttactttttg ttccattctc atattaagta acgctttaac ggtcatcttc
    14101 tcaccgaata aaatacgttt tagcgcatct gcatgtggac gtgttggatc aatggatgcc
    14161 tcgatttctg ctgctgcgat agtatacaat gtcgcttcgt caatttgatg tttatgatgg
    14221 aaatgatgaa tcaaagtacc gagttgattt tgaataactg catgctgaaa ctttgcgatg
    14281 actgcttcaa tcttatcact cactaagctg tcgttcgtaa tttcaaaatc agggaccgtt
    14341 tgttttaatg tttcaggata aatccgcgaa cctcctaagt cacgtacaat aaaggacagt
    14401 gtctcatttt ctttatccat ttgcagaatt gtattttgtt gatgtgcttc taacgcgata
    14461 ccgtattgtt gaatatacgc aatgagtggc ggaatcagtg cttccatgta ttgacgcata
    14521 aactgctgta tcgtttcccc attcatgtcc ccgtatagat actcaatcaa actatcgacg
    14581 acgacttggc catcgacagg atttacttgc gtcagaacag ctgtcacaag ttgcgtatag
    14641 tcatgtgtat gcacttcagg agaatgacgc acaatcatcg caaactgacg tgccaaatct
    14701 gcttccacat caatatgcgc accatacggt tcacttgcaa cagtcaaggt cggataaatg
    14761 tctaacatgt cttgtaattg ataactgagt ttaggaccat cgaccgtcgt cacagtcgaa
    14821 atagtacgca cagcactcgt tgcttgaacg ttaacaggta atttcacatg atatgggtaa
    14881 tgcagtaagc gcatcgttct aaatgataat gtcgctttcg aatctactgt aaatggggtt
    14941 ggaataacgt cgtgttgcgc aatcatggtt ttaaaccgcg tcgtaatcac attggtatat
    15001 tgccatggat gaacgagtat aatccgataa tcatccaacg tcccctcata tgtttgcatc
    15061 cattgtctta attgactttc tttatctggg aacatctttc tcaatacgaa atcctcttca
    15121 ccagtcattg ttgtactttt taataacgct ttacgtacga gtaccatttt taatggaatg
    15181 attttcataa attctggcgc atattgttga atttcttctg cattgagtgg caatttcgtt
    15241 ttcgttaatg gatgtgacgg gtgcccttcc caaaccatac cttccgtgta accaagtact
    15301 gaaaataatt catcaccatt catatgattt aaccatgcaa taaagttcag cgtgtctggc
    15361 atgcgtgaaa attttaacga atgccgcatc acacgttcac gttgacgcag ctgttgatag
    15421 ctcagttcaa gaccgagacg actatgtagc aactcttcaa ccaattgatc gtgaaacgtt
    15481 atgccaaaat gcgtgcctaa aatctctatc aattgttcta ctgtttcaat cgtgacgtcc
    15541 tccgtgccaa cacgataaac aataggaccg ctcaattcga gttggtataa cgtacttatc
    15601 gtctcatatt gaactgctaa cacatgttga tgatattgaa tcatgacttg attttgtttg
    15661 aattgaagtt gtgttttttc aggaaataat tgttctttca tacatgcgat gagaatccga
    15721 tattgaatat tttgatctgc attcagttta tgcgtgagtg tcatgaactg tcttgcctcc
    15781 attcatctta aaatttgtta aaaagcctaa aattgcaatg atggtcgtcg cgccacccat
    15841 aactaaaaag gtcgtcgtaa taccaatcaa ctctgtaaaa taactgagca acattgcgcc
    15901 aagtggaatc atccctctat ccatcataat gacgcttaaa attttacctc tactctcttg
    15961 ttcaacatca ttttgaaagt aaatgcgatt cgtcgttcgt gcaaactgac caaagagccc
    16021 aacgaaaaag atcattaaaa ataagcctat ttcgccaagg gggtataata aaagtaacgc
    16081 aataccaaac agtatcgaac tgagataata acaattgtca gttgaaaatt tttgtagtac
    16141 ataaggaatc gtgagcgttg ctaatatacc acctattgca ctcactgtca tcgctgtacc
    16201 aaataccgat gcgctattag gatatacctc gtctgttaaa atcggtaaca ttgtggtata
    16261 agaataaccc atcgccatga tgagtagcga cgtcataaaa attcttctcc cttgcaaatg
    16321 cagtttaaaa tattgcatcg cgacagctat tgaaaattgc ttgtttttaa caggtttaac
    16381 gactgccaat tttaacggaa ggcttgaaac gagtgcaagt gcataacaaa tcgtttgtac
    16441 gacaaatgca atcggcacat catacactgc aatgataaag cccgccacag caggtccgat
    16501 tgagcgacaa acatttaaca aaaaggaatg atatgaaaca gctttagaaa cagtaagtct
    16561 ttcggagatg tcgggtagca cagcttgtct caccggtgtt tcaatggcac tcatacaacc
    16621 gcgcaaacag gcatatatgt ataaataaaa catgggtatg tcattcatga acaatacaca
    16681 taccgttaaa gtacctgtaa tgaccatcga actggtcaca gtcattttaa tcagcgttga
    16741 acgacggtaa cgatcagcaa tactgcctgc ccataaactt aaaatgaaaa tcggtgcaag
    16801 tctaaagaag ttgatgagtg caaggtccat tgggttttca ttgagttgat aagcatacca
    16861 gttgagtgca atctgaccaa tccaattccc taaaaataat aaaaaggtac tcggaaaaaa
    16921 ccattttgcc aaaatattca ccttctttaa ttgataatga ttctcatttc cgatattatg
    16981 gattatacga atccttttcg tatttgtaaa ataaaatgaa tgaggtgtcg tcatgaaaac
    17041 ggaacaaaat catctgagta tgatggagaa agactttaca aaagatgaaa tggaaaatta
    17101 tcaagcagtt ctccaatttg attcgaactg ggctacacaa tttaaacgcc acgttttagt
    17161 aggtcgtgac aaaatcactg cacgactgat ggcatcactg tatcgtgaaa acttggttgg
    17221 aagttatacc catagcacgt ttatacaagc agaacagtta gcgcactctg ctattccatc
    17281 cggccaacta cttatgattc actttacata tggtcagctc acgttatatg cccgtgtcat
    17341 cagtcatcac gcatttaacc gtgttgatgt gacaggaccg ttttattgga gaacagcaga
    17401 tggagaggac cgtcgcgtat tgcatcctaa cgaagtactt gatgtcatca ttaatgaaga
    17461 cacacgctat caaggagcag ccgcagaaca gtttcgtgat gatatggaga atagtgccgc
    17521 acatatggct ctggcgctga gttaccaagc acaacatcca ttaaaagacg cgccatcatt
    17581 acttgattat atagaagcac aggatgatcc ttacttaact tctgagcaac tcgttgttga
    17641 agggcatccg ttacatcctg gtgcaaaatt acgtaaaggc atgtccgcac aagaaaccat
    17701 tgattactcc tcagaatatc aacacacgat gctgatgcag ttcatacttg ttcatcatga
    17761 tgtcgcacgt acaatggcac aacatggcac atatgaagaa gcggtctatc atgcatttga
    17821 cgggttgaag tcagttgcgt tacaagcgat aggttcggat gcgccactcg aagattatat
    17881 gcctttaatc gttcatccgt ggcaatatga acatattatt cgcacagaat accaacacga
    17941 acttgataca aaagcaatca tcccgttaga ttatacaaaa tcatattatg caggattgtc
    18001 ttttcgcaca ttaatgccta aaaagcctga cgtgtcaccc catattaagc tttcaactaa
    18061 tgtgcacatt actggcgaga tccgtactct gtcagaacag acgacgcata acggaccttt
    18121 aatgaccaac attttaaccg acatttcagc acgagatgca cttttcaaca acgtctcaac
    18181 ttcaccagta ccagaaattg ccggcgctca tttttatcaa ccgaaagaca ggcaccctga
    18241 tgaacaagaa cgacgtagcg aacagttagg cacgctattt agacaaaata tttatgacat
    18301 gattgacagt gagcgcctgc cagttattcc atcaagtcta gtcgtcacac atccagaaac
    18361 agcgcgtcca cttatcgtcg aattggttga acgttttagg caaacaaatg acaccacaac
    18421 agacatcgac gtacgtgcac agtggtttaa aacatacgcc gcttcactca ttgattacgt
    18481 cgtgccacta ttagtgaaat acggtatcgc attagaagca catttacaaa acacgattgc
    18541 tgtatttgaa ccaagtactg gcgccttttc acatatgctc atccgtgact ttgaaggctt
    18601 acgcatcgat gcagaacagt tagcacaaat gggctatgat acgtctcatt tccatgaaaa
    18661 atcacgaata ctgacgaaga gtcaaacatc tgtgttcaac aaagcctttt actcaacgat
    18721 tcaaaatcat ctcggtgaac tcgtcgcagt gctctcacgc ttttatgatg atgttgcact
    18781 cgaaaacacg ttatggtcta tcgttcgtca acaaatcaaa caatgttttg acaagcttga
    18841 agccgctgac attaatccag aacgtttagc ccacatgcaa aacgtattct ttaatgaaaa
    18901 gattgattat aaatgtgtga caacgatgcg gttaatggat gaagcacatg aatacacata
    18961 tattaaagtc gacaatccac tttcaaaatc attgatttaa aagtagcaca ataacatatt
    19021 tctactaaag attgagtcaa aagtatttct tatcctatgt aattgtatta aaataactta
    19081 tagacaaaaa ttacatttga ggagaatgac tatgacaatc atgcgtacct taacgtttat
    19141 gttaagtatt tttatcgtag gaatggttga aatggttgtc gctggcatta tgaatctgat
    19201 gagtgcagat ttaaatatat cagaagcatg gatcggtcaa ctcgtgacga tttatgcttt
    19261 tacttttgct ttaacaggtc ctattttagt gaaacttacc gaaaaatatt cacctaaaag
    19321 tgtgttacta tcagcgattg ccttcttcgt aataggaaat ttgatgattg cactctcccc
    19381 taactttacg attttaatta tcggtcgtat catttcgtca gcagccgctg cattgatcgt
    19441 cgttaaaata ctttccacaa ctgtcgtatt agcgcgacct gaaaaccgtg gtaaaatgtt
    19501 aggcattgtg tatacagggt ttagtgcatc caacgtattc ggtgttccga ttggtacatt
    19561 aattggcgat tgggcaggat ggcgttttac attcgggctc atcatcttag tcggattgat
    19621 tgcaggcgta ctgctcacca tttatttgcc aaaagaagta aaatcatccc tacagcctac
    19681 gcaaaatcat actagccgaa ttttagacaa aggagaagtg acaaaactcc tatcgattac
    19741 ttttatatta ttaacagcaa attcagtggc ttatatttac attaatccac tcattttatc
    19801 tggcggacat aacatccaat ttgtctctct tgccctactc ataatcggta tcgcgggcat
    19861 gttggggaca tccatggggg ggttctttac agataaactg tcatttaaaa catggctgtt
    19921 agtgagtggt ggagcctttg tcatcgtcat gctcgtttta aatcaacttt ggacagcatc
    19981 tactatttta ctgattgctt tattcatttg gcatattatt cagtggagta ccaatccagc
    20041 ggtacaatcc gggctcattg atcaagtaga aggggataac agtcaagtga tgagttggaa
    20101 catgtctgcg ttgaatgcgg gtatcggttt tggtgcctta cttggtggtt taatcgtgtc
    20161 acatatcgat ttacatgcga cgatttattt cgctgccggt attggcttca tcggctttat
    20221 cattatcgtg atgttgaaga aaaaacgcgt cgcttagact tgattaacaa agatataaaa
    20281 aagggaggta tacgccatat tccagcgtat acctcccttt tttatatctt attgtaaacc
    20341 tttgttctcg ttttgatctt tgtttttctc atgcttttgt tgccattctt tacgtgtcat
    20401 cacgtcatcc acttgcatgt taacttcaac cacgtctaaa ccagtaatgt gtttcacttg
    20461 ttctttaatt aattctgtta ctttacggaa gattttcggc gcagattcac catattctaa
    20521 aataactttc aagtcgattg ctgcttgttt ttcgccaact tcagcagata caccttgtgt
    20581 cacattgttg ccacctgaga atgaaccgct aatgctatcc acaaagccgc ctttcatatc
    20641 taaaatacca cgaacttcac gtgctgcaat ccctgcaatt ttttctacaa cttcatcaga
    20701 gaaagttaag ctatttgaaa attgttgtcc ttgattatct tcacgttgtt gtctttcttt
    20761 ttcattcacg cctgtttctc tattgtaact ttcttttact ttattatttt caactgtcat
    20821 ttcaaaaact cctttattat ttattttatt tttctttttc catgattatt gaattaactt
    20881 aaccgattaa gtaaatttaa gaaatcttgt gtacggtctt taatataccc cacaccaata
    20941 ccgattaaac ataatacgat gattaaaatc gttttccaaa agccaagtgt taaaaacaaa
    21001 atggcaataa tgaggaagaa gaaaaaccca atgatacgcc atttatagct ttgtaatagc
    21061 ttcgcaaatt gctctactga atctcgctca ctttgaccgt ttcgattttc attagacata
    21121 ggacccctcc tttacacgac tcgtggacca ttgtctcttt tttggtcacg gacattgact
    21181 ttaactgatt tgacatgcaa ttctgagaaa cgttcaacgc tctctttaat gtctaatctt
    21241 acttgttcaa cgagtgatgg aacattcgcc gattctgatg gaacaataaa atctgttgta
    21301 atatcaataa aactattctt tttcttgtta taaagttttg atacgacgtt cggttgacga
    21361 acctcatcat atttcgaaag cgtatcataa accgtgtttt cgatagactt acgtgaaata
    21421 taaatatggc cgtctgaata atctttataa agccccggtt tacgatatgt gggtttgaaa
    21481 gctcttaaga ataaaatcaa accgataaga ataagtaatc cagctagacc aattaataag
    21541 ggttggaacc aattaaactg ataaaagtaa tcttgatact ctttgattgg ctgataatca
    21601 atatacataa ataacaagaa acctacgata atgactatca acaagccaag aataaaattt
    21661 ttgattcgtg tcataatcaa atgccacctc ctattcaatt gtttacatca ggtatatacc
    21721 ctcattttta acagaaaaac taaatttttg tcatatttcc aaaaaattta tttgttattt
    21781 tgtatctaag ttttttcgat ataattatgt ttacattttt ttgcttaaaa gaaatattga
    21841 aaaagatatt gttatcattg aatcgcagtc aatcaattgc acgtcatttt ttaagaatta
    21901 gataccatta aaaaaagaag tgaaactgtt atctaacaat ttcacttctt aatgtttagt
    21961 gatcattttc ttttacttaa tcgtggtcgt tctgcagcaa gggctttgaa taatgaccaa
    22021 atcataaaga taatcacaaa tgagaaaggg agcgccgcaa taattaataa attttgaata
    22081 gcttgcgttc cacctgtcag taacataatg aatgcaaaaa gtgcgagcat aatgccccaa
    22141 ctgactttca cccaactgcc tggataattg tcaccatttg tactgagcat accgagcaca
    22201 taagtcgctg aatctgctga tgtcacgaag aaaatcatca cgaccacgag tgtgacaata
    22261 ctcatgacga agccaagtgg aaaatgttcc aacgtcgcaa acgtggctgt ctcaatggct
    22321 tcacccgcaa tattcgcaat accattatcc tgtaaataaa tagctgatgc gccaaatact
    22381 gcaaagaaaa tgaaacagac gagtgatggt acgaataaca cacctatgat aaattcttta
    22441 atcgttcgcc ctcttgaaac acgcgcaatg aaaataccta caaatggcgc ccatgaaatc
    22501 caccatgccc aataaaagac cgtccagttt tgaatccatt gtgacttttc tggattgtta
    22561 atcgttaaac gtaaactcat atcgaaaaag tgtgcaatgt aatgacctaa actattcgta
    22621 aacatgttca atatgaaaag cgtcggccca atgataaaaa caactacgag cacgataaaa
    22681 gcaagaatca tgttaatatt acttaacatt ttaattcctt tacttagtcc agaccatgtc
    22741 gaccaaataa ataacgccgt cgccataatg atgatccaaa tttgtgttgt gaagttggct
    22801 ggaatattaa ataagaaatt taagccttca ctaatttgaa gcgcaccgaa acctaatgtt
    22861 gccgatacac ctgttactgt cgcaataacc gcaagtatgt ctaacaattt gccaagcggt
    22921 ccttgcatct gtttttcacc aaacagcggt gttaacgtcg cactcactaa tccaggatag
    22981 cctttatgaa agttgaaata tgcaaacgcc aacgcaacga tcgcgtagac cgcccatgca
    23041 tgaatgcccc aatgaaaaaa ggcgaattgt aaactgtcat caatagccgc ttgcgttcct
    23101 gcttgatgaa taggtgtcgc cgtgtatgca tgtgaaatgg gctcggcagt cgtccagaaa
    23161 acgagaccaa tccccattcc tgcactaaac aacatcgcaa accatgattt taatgaaaat
    23221 tccggctctt ccccttcttc acctaatgta atctgactgt atctcgaaaa aagtaaataa
    23281 acgcaaatca agaaaatagc caataacaat aataaatagt accaactaaa attttggcca
    23341 atccaagtag tgatcgattg cgtcgtttct tccatctgtt ttggaaaaat tgcgccaact
    23401 aggacgaata aactacataa cagtaacgat atccaaaaca cgagactcac atgtttcttt
    23461 ttctttgttt gtttcatgac tttaacttcc ccttaatcgt tagttaacag tcatattccc
    23521 tcttttgtgc aatttattct acaatttcaa tgacaagttt gccgatatgg gattgtgctt
    23581 ccatcatttc atgcgctttc aatacatttt ccggcgttaa acctgtaaag actgaattta
    23641 aagtcgtttg atattgatct gcatcgactt ttgcagttac atcttctaaa tatttgcgat
    23701 acatcccttc gtcgacacca tgaattgcac gcgcaaacat aaattcatgc gtaaacgtaa
    23761 tgcttttctg tttcaaagcg ttcaaatctt gatttttatt aaacgcaaca atcgtcgcaa
    23821 tatgacctct aggctgtact aagtcaatca tcacatcgta atagtggtct gtatcatatg
    23881 tacagaaaat gtaattggga cgtgacaagt tttggtcatc aaattgttta gctaaatctt
    23941 ctttatgatt taacacaaca tctgccccca tctttttaga ccaagcattt gtttctggac
    24001 gagatgccgt agtgaccacc gtcaaaccat acgttttcgc tatttgcgtg gcgatacttc
    24061 caacaccgcc tgcaccgtta atgatgaaca acgtcttgcc ttgattctgt tgaggatttg
    24121 gagaaatgtt gaatacatcg aacaatgttt cgtaagccgt aatcgctgtt aaaggtaacg
    24181 ccgccgcttc agcgaatgac aatgttttcg gcatatgcgc taaataattt tcattcacga
    24241 gctgatatgt ctgatttgag ccatctcgtt gattcgatcc tgaataatat actcggtcac
    24301 ccggtttgaa atccgtaacc gcatcgccga ccgcttcaac cacacctgcc gcatcaaaac
    24361 ctaggacacg tgcctcagca tttaacgggg cttgccgcat tttcgtatca accggattga
    24421 tccctgttgc gtacactttg attaaaatat catgtgcctc tggtgttggg agctcacgcg
    24481 atactttttc aaacttttga ccttctgcta attggaacgg ttgagttgca ataattgctt
    24541 ccatagattt cccctgcttt ctatttattt ttaagcattg tactcgtgtt tatgcttatt
    24601 ttgcttgata attgtagtat aacacgcttt gaaaggaagt cttatatgct actcagcatt
    24661 ttagattata gtcctatttt tgaagaccgc acaccgcaag atgcacttaa tcatagtgtt
    24721 gatctcgcgc gttatgctga aaatctgaac tttcaccgct attggctagc tgagcaccat
    24781 gaagttcatt ctgtcgcatc aacagcacct gaaattttag caacaatgat tttagaacaa
    24841 acttcacgca ttcatgttgg cgccgggggt attatgttgc cacattacag tccatataaa
    24901 gtagctgaaa cttttaaaat gctagaggca cgccatcctg gacgtgtcga tattgcactt
    24961 ggaaaatcac ctagttttca aaatgtgtct caagcattga atgaagacaa acaaacttta
    25021 acagactttg atcagcaatt gatggactta acaaaatatt ttaataatga cagctcgacc
    25081 ccacatcgtt ttcagcattt aaaagcaatg cccgtcattg aaacgcaacc gcaattttgc
    25141 atcttaggca cgagtgaaaa cagcgcagaa cgagccgcac aattaggtgc tgtttttgta
    25201 tttggggcgt tcggacaaaa aacgatagaa aaacaacgta ttattcaacg ttatcgaaaa
    25261 caatttcaac actatcatcc tgaggggcaa ccttatctca tcgtctctac tttcgtctta
    25321 gcacatgaga atagtcaaat ccgtgcacaa ttagaagaca gtctgcatta ctggttgcaa
    25381 cgcattcatt atttaaaaca gccgaaaaca cttttaagtc cagaaacgat acaacagaaa
    25441 aactggagtg tacgtgaact tgaaaaacgc gccgaaaacg cgcctcgtat catcagtggt
    25501 gacggagaaa ccgtagcgca tgaactccac gaattgcagc gtacttttga tgctgatgaa
    25561 cttttattat ttcctcaact ctatggtgag gagaatagaa aacattgttt agcactcatt
    25621 gcaaagtatt ggtgaaacct aaataaaaag gtaatgcttc tcatagcgat aagcttttaa
    25681 cgctaaagaa cacattacct tttttcattt ttcaataatt tgttgatttt ccattgaaat
    25741 ctatcatgac tatcagatgc gctttaactt gggaaggatg agcaaaacag caccatcaat
    25801 tagttttctg tctcgcttct gaatatcttt tttgtttcgc ataactgtaa tgacccggat
    25861 aataatgcag ctgtttattg tcaatccagt acgtttttga aaagtgctta tccaaaaaat
    25921 atcgatcgtg tgaaacagca ataacagtgc catcaaaatc ctctaaagct tcttccaatg
    25981 cttctttggc atcaatatct aaatgatttg tcggctcatc aagtataagc acattgaatt
    26041 gttgagaaat catttgcgcc catcttaatc gcatcttttc accaccactt aaatctttta
    26101 cttttttata gacatcatac ccataaaaaa gatattttgc cagatggttt ctggcttctc
    26161 cttctgacac atgtgcatat tgtctaaaag cctcaagtac tgacatctct ccagtattaa
    26221 attgatgttg cgccaaataa ccaatgcggt ttgtttcagc aatttgaaca tgaccttcgt
    26281 caggcacaat ctctcttaac aacaatttta acagcgtgct tttacctgtt ccatttgcac
    26341 ctacaatggc cactttatca cggcgtctaa ttttcatatt aaccccttca aataggatat
    26401 catcatacat tttagcgaca tcttttaaca caaaaatatc ttttgaagca ctttccgatt
    26461 gggcaatatc taatttcatt ttattgtatg ctagtctggg tttaggtttg acttcgatac
    26521 gcgccagtgc tttctccatg cttttagcac gacgatgcat cgacgcattt ggtggctttg
    26581 cctggttcgc ccaaattttt aattgcttaa tttgggcttt cattttttga attttcttct
    26641 gctgggtttg atatgcttta aattcgttta aaatacgctt ctctttttca atgacaaaat
    26701 ttgaataatg accgggatat acatataact gctgttgatc aatttctaat atttgagtga
    26761 ccgtttcatc tagaaagtaa cgatcatgtg aaattaccat cacggcacct ttatattgtt
    26821 ggataaactt tgttagccat tcaatacttt ctatatctaa atgattcgta ggttcatcaa
    26881 gcagtaacaa ttctggtgat tgaagtaaca acatcgctaa acccactttt gtctgcattc
    26941 ctccggataa attggaccat tgctgcgttt taaggtgtgc aatttttaaa ccgttgagca
    27001 caatatcaat tttgtaatct ctgtcgtaac cccctaaagt ctcaaattca ttttgcaatc
    27061 ggtcatattg ctttaaaatt tgattgatgt catccgcccc ttcaaccatc ttaatttcca
    27121 actgtctcat tcgttgttcg ataccattca aagtatcgaa ggcttgataa agctggttta
    27181 ttacaatagc atctggtggt agatttggga tttgtgctag gagacctact ttgacatcct
    27241 tagcaatact aataaagcct tcatctgcct gctctttttt ggctattaat ttaaataaag
    27301 tcgttttccc ttcaccattt cgccctatta aaccaattcg gtcattttga ttcacttcaa
    27361 acttaatatg atcaaagacc ttatttccat tatacgattt cgtgagttga ctcacattga
    27421 cgatattcat tttttattcc tccatatcac tagaggaaat tgtgtcagta ttcctctaga
    27481 agatgtattt gtttaaaatt agacagacta caccaatttt taacaaaaag cgcaaatttt
    27541 ccacgtataa tatggacaaa tcttacacgc tttacatctt ctaaaaacat accgacacct
    27601 ccgttcatat aatgataaat ctaattgtag cctagtttca cttgtgattc aaatcactta
    27661 tacttatttt aactcagtca gatttttagc tccaacctta tttgattgct atgatgatag
    27721 aaatagatta aaatagcgat ttaattttca ctatactaaa ttttttaaag gagagaaact
    27781 cccctaatgt taaaacaagg tttaacgatt atagacgttc agaatgatta ctttgataat
    27841 ggtaaaatgc atcaaaaaac caagacccgt ttaaaagtct tggtttttca tactatgatt
    27901 caatgattcg tgtttctgcg agtttcttat accaatatgc actctttttc ggatagcgtt
    27961 gctgtgtttc aaagtcaaca tagaataaac cataacgttt ttcatagcca ttggaccatg
    28021 agaacacgtc cattaatgac caaatgaaat aaccctttac attagctcca tcctcaatcg
    28081 catctgcaat cacttctaaa tgttgtttga cataatcaat acgcgcatcg tcttgaactg
    28141 tatcattaat aaattcgtct ttataaccta atccattttc tgtaatataa atttttttgt
    28201 aattaggata atcttttttt acacgcataa tttgatcata caaaccttga ggataaatca
    28261 tccaatccca atctgttcta gggacatcta catcaaattc acgttgccca atccctttca
    28321 gttggtattt tgaaccgcct ttgtcacctt tagaattatg cgtaatttca ctttcacctt
    28381 caaaactacg catccaatca ctcatataat agttaattcc taagaaatca tttaagtctt
    28441 tggcaacttc tagtatttca aaatcttctg gccttaaatc cagtgcccca ccgttaatac
    28501 tcaaaatgtg gttaacgcca tccatcgttt ctttagagta atgccctaaa tacgttgcgt
    28561 ctaatataaa cttattatgg ataatatctt ctaattcagc cgcgcgaaca tcttcaggat
    28621 cgtccgggtt aaaaggatat tttgtaggca aggcatgaac aacaccgatt tcaccttgat
    28681 gaccttgttc cttaaataaa gcaactgctt ttgcatgtgc aaccatcata ttgtgatgcg
    28741 attgaaacac tttttcaaaa tgatattgaa taccgggtgg gaatttccct acaagatact
    28801 gaccatcccc aataggtccg atttcattga atgttgtcca ataattcact tctttaaact
    28861 cgttaaaaca aaattcagca tattcaacaa aatgttgaat attctctctg tttaagaagt
    28921 caccattaga atgtaaagct tctggtgtat caaaatgatg taatgttacg aaaggttcaa
    28981 cgttcctttt catgcattct ttaaaaagac gatgataata atctacacct ttaggattaa
    29041 cctctccata gcccttagga aaaatacgtg accatgcgat tgatattcgt attccattca
    29101 caccaaattt ttcacttaac tctaagtcaa caggatagcg atgataaaag tcgctagctg
    29161 gttcggctgt gtaccaataa tttttttcta aataagtatc ccacgctact ctacctttac
    29221 catctatatt tgtcgcacct tcagcttgat atgctgctgt agcaccacca aaaataaagt
    29281 cttctggtaa ctttttcatt agattttgat ctccttttat ctaaaatgat cttgcacaaa
    29341 tttcaaagct gcttggccat cacgagtaag gctaatgtat tccccacctt gtgtcttagc
    29401 aagctttatt ccgagcctat ctgtatcttg tttaatatct tgatagtttg aagcaacttg
    29461 tggggctaaa atgacgagat cgaaatcctt cataatatcc atatgtgcgc cataactatc
    29521 tgcagcagct ttaacaggtg cttcgtactc cgtagcagct tggtttaaag cgttggctag
    29581 taaaccactt gttcctcctc cagcacatag tacaagtaca ttaataggtt tagtaatagg
    29641 gtttgaactg tttgcttctt gagtcatatc agcgacggat tgatttgtag acgcatttaa
    29701 aatagcatct gcttttgacg tattaaagtt ttctcccact tttgcatgta attcgttcgt
    29761 actgtcaata cctttcaact catcatctaa aatttgatta tcatagactt tgaagaatgg
    29821 atagtaaatg aaagtatcaa caacgattaa agtcattgct aaaacaaatg accacacacc
    29881 aaatcctgtc cccatcacga ttcctaatgg acctggagtc gtccaaggta agaacacact
    29941 aaaactattc ataccaatga catcaacaaa aaacttaaaa atccacacat taataatggg
    30001 tgccatgata aatggtataa agaatatagg atttaatacg atgggtgcac caaataaaat
    30061 aggttcattt acaccgaaaa atgtaggtac aactgaggca cgcccaattg ctttattacg
    30121 ttttgattta gacagccaca taaatataaa cgggactact aatgtcgcac cagtgccccc
    30181 catagttacg ataaacattt gtgtacctgg tgttaaaatt ttatctgcat gttcaccagc
    30241 gtgtagtaat ttaaagtttg tttcgatatt ggcataagta atggctgcaa tagcaggctc
    30301 cacgatagaa ggaccgtgaa taccaacaaa ccagaaaaac gcaaaagcac caaatataat
    30361 tgtaataccc acatagccat ctgctgcggt aaataatggt tcaaaaacct ttaaaattga
    30421 ttcagcgaca tttgttttat tcactgatct tgaaaggata tccaatccat acaaagttaa
    30481 aataacaagg ctgaatggaa ttaaatcttt aaacacttgt gaaatatttg ggggcacttc
    30541 tttaggcatt ttgattgtaa tattattttt aatacaaatg ttataaatca tcacagtaat
    30601 aaaggcagat aaaaatgctg ttagtaagcc tttcgttccc atgaaagcat ttgcaaatcc
    30661 tcctgcttca agtgtattcg aagctagaaa taagaaacca ctcatcgaag ccagcatcgt
    30721 cgagataaag ttgatttgat ttgttctttc taatttacga ttatatgaat ccgttagcgc
    30781 tttagctgtt gttcccgcaa caaataaccc tacaattccc attgaataat ggtatggctt
    30841 cataatgagt gcttcggtct ctttactcca cttgaaatca aatatattcg gtacataagc
    30901 aatcaataag aaaatacttg aaaataaaat aattggcata gctgagataa aaccgtcacg
    30961 aatcgctctt aaataaatat tacgagaaag tttttcaaaa aacggtttcc ctttttcaat
    31021 aaacccaatc agtttgttca tagatgtcag ctccctcgtt tgtacaattc gatgatatgt
    31081 tttaacatgt cttttaataa aatggttgtc attaagtgat cttgtccatg catcatggtt
    31141 acgctgtaag caatatcatc acccatcgct tctttttgta ataaactcgt ttgtgctttg
    31201 tgcgcatcca caatacattg attaccttct tcaatcagtt gttcagcttt atcataatcg
    31261 ccaacttgtg ctgctgataa tgcttctaaa tattttgagc gtgcatctcc agcgtatgcc
    31321 acaatttcaa atcctaacat tgcaacttct tctctgttca tcctcattac ctccaccgtt
    31381 tgttaattat ttgcttttgt atgaaacagc tgtttctttt agcacatgat ttagttcatt
    31441 tatattgtga taaccttcag tgcgcagcca ttctcttgct gcctcctcac cgttttctat
    31501 atatgctttc actgcaccag accatgttgc acgtccacat aacacaccat taaactgcgc
    31561 tccagcctcg tgtgcaaatt ttaatgtctc ttggaataat tgggcagaaa caccggcact
    31621 caaataaata tacggtaagt gtgttgcttc atcttgttgc ttgaaatacg cagctgcttc
    31681 ttcacgcgtg tacacaaatt caccttgact gaacccttcg acatagttca tatctacagg
    31741 tacttccact tttaaaacat ccactccaaa acgttcattt gaaaatacgc gcatcgcttc
    31801 aataactttt cttggtttta cctttgcgta ttccttactt ttgttatctt ttattgaatc
    31861 atcatatgct agaatttcta aaaagaacgg tatctcttct gccttacatt ctgaaccaat
    31921 tctctcgata tatgcctctt tttgatcatt gatatatgct tcatcatcga catcataata
    31981 gagcaagaat ttgacagctt gtgcgcctgc ttccttaata cgtttggccg accaatcaac
    32041 taagcagtca ggtaaacgtc ctttagcatt cacgtcatat cccgtttttt catatgctaa
    32101 taataaacct gtcgagctat gtcttacttg tgttgcaggc aaaccatatt ccggatctaa
    32161 taaaatagaa gacgcataag gtgtgagctc ctctgaaact aattttttta attgttctat
    32221 atctctaact tcgggttcag atgcttgaaa ttgtgccatc atacgtttta atgcgccacg
    32281 ttggtcaaaa gccaatgctg aaatgattcc attctcgtca cttaagcgtg ctaataattc
    32341 ttgtttgtta ctcattttta cacctctaca tttaataaaa tcaatacact caaatctgca
    32401 aatatacttt aatgatttag ataagttaat cgtgatattc tccgttgtcc cacttttcta
    32461 aaaactcatc aaaaaaggaa tcttcttttt gattttcatt ttccgactca acttgcgcta
    32521 ttttttctat caacctttta ttttctgcgg tagggtgata ttcagcatta ataaaggctt
    32581 cgactatatc acaaagtaat aactcgccaa taattttgcc accaaagcct atgacatttg
    32641 catttagttc ttccttagca tagatagctg atgacatatc acgaaccaat gcagaacgca
    32701 cacctggcac tttattgaca gcgttattga ttcccactcc tgtaccacaa atacatatcc
    32761 ctaaatctgc ttctccactt gtgacagctt ctcccacttt ttttccaaaa attggataat
    32821 gtgttcgtgc aaaatcatac gtaccacaat caagcacctc gtgacccaat gattttaaaa
    32881 attgtgatac ttccattttc gtatctgtta caatatgatc cgaaccaatt gcaatcttca
    32941 tctcatgctc ctcctcttat cccattttat ttaacatgtc tacacgaatt tggtgacgtc
//
