LOCUS       NC_014925              21543 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Staphylococcus pseudintermedius HKU10-03, complete sequence.
ACCESSION   NC_014925
VERSION     NC_014925.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius HKU10-03
  ORGANISM  Staphylococcus pseudintermedius HKU10-03
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K., Woo,P.C. and
            Yuen,K.Y.
  TITLE     Complete genome sequence of the veterinary pathogen Staphylococcus
            pseudintermedius strain HKU10-03, isolated in a case of canine
            pyoderma
  JOURNAL   J Bacteriol 193 (7), 1783-1784 (2011)
   PUBMED   21278300
REFERENCE   2  (bases 1 to 2617381)
  AUTHORS   Tse,H., Tsoi,H.W., Leung,S.P., Urquhart,I.J., Lau,S.K.P., Woo,P.C.Y.
            and Yuen,K.Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-DEC-2010) Microbiology, The University of Hong Kong,
            Pokfulam Road, Hong Kong, China
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000185885.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 09:14:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,530
            CDSs (total)                      :: 2,448
            Genes (coding)                    :: 2,410
            CDSs (with protein)               :: 2,410
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 14 of 38
            Pseudo Genes (incomplete)         :: 26 of 38
            Pseudo Genes (internal stop)      :: 5 of 38
            Pseudo Genes (multiple problems)  :: 7 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:32:32
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 123953
            Orig. end                         :: 145496
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002439.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA and bacteria are available from Prof. KY Yuen
            (hkumicro@hkucc.hku.hk) at the Department of Microbiology, The
            University of Hong Kong.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21543
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="2"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21543
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21543
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11543](-)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11543)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     misc_feature    302..312
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    595..607
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            1654..1935
                     /locus_tag="SPSINT_RS00565"
                     /old_locus_tag="SPSINT_0117"
     CDS             1654..1935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166378.1"
                     /locus_tag="SPSINT_RS00565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0117"
                     /product="hypothetical protein"
                     /protein_id="WP_201800462.1"
                     /transl_table=11
                     /translation="MNRIRVVYIVNVLNYLFLIVGGLICVQLMLAFGDLLLYFEATSLA
                     AGIFSLWHLNADDAKLQKVGLIWFIINLLNIFVLTPLIILVLFFGISF"
     gene            2273..3280
                     /locus_tag="SPSINT_RS00570"
                     /old_locus_tag="SPSINT_0118"
     CDS             2273..3280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498204.1"
                     /locus_tag="SPSINT_RS00570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0118"
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="WP_014614841.1"
                     /transl_table=11
                     /translation="MRKKFIAAVIGTTAAATALSAHADASTTYRVQPGDSLWAIATKYN
                     ITIAQLKQYNGLNSNLIFPNQVLKVSGGSSTSRTTTHHSSHSTTSSTVYTVRYGDTLSG
                     IAARYGTTYQNIMKWNGLNNFLILPGQKLNVSGPSTTPSRSTAKKPAPKTSSRNASYYT
                     VQPGDSLSLIASKYGTTYQHIMELNGLTSFLIFPGQQLKVSGSAPSRQTTPTPSPSYQS
                     PTFNHQNLYDWGQCTWYVFNKRKEMGRPISTYWWNANAWDDNAARDGYTINNQPAVGSI
                     LQSDLGYYGHVSYVERINADGSILVSEMNFTAAPGILTYRTVPAHRVSAFKYIH"
     gene            complement(3672..3947)
                     /locus_tag="SPSINT_RS00575"
                     /old_locus_tag="SPSINT_0119"
     CDS             complement(3672..3947)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728571.1"
                     /locus_tag="SPSINT_RS00575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0119"
                     /product="hypothetical protein"
                     /protein_id="WP_015728571.1"
                     /transl_table=11
                     /translation="MAKKSKKSLSVLSTALTGATLVVDFYNSYIYRSKNRKLSYISVGL
                     GLVDVVLSFYLSLGAKSKFTKAWSFFSASRQVWSGIQKIQAIRTRG"
     misc_feature    complement(4064..4080)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.15"
                     /tool="antismash"
     misc_feature    4106..4117
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.71"
                     /tool="antismash"
     gene            4252..4767
                     /locus_tag="SPSINT_RS00580"
                     /old_locus_tag="SPSINT_0120"
     CDS             4252..4767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166374.1"
                     /locus_tag="SPSINT_RS00580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0120"
                     /product="hypothetical protein"
                     /protein_id="WP_014614839.1"
                     /transl_table=11
                     /translation="MNQVTKIAVATTLSLGTLLGATAGASAIHADAHAATEQQTPYYTY
                     NGLFNFKGNKALEDKNFYRALQHDNFKYEGLKVGQSTFADVKKAVGNDVKKYYEEKGVT
                     YYEKNDVIFGIDSEGKLVNMTLLIEKINHSDKSVRDHVKQGEIYDTKTTHVAFYSGNSI
                     VIKAKESR"
     gene            complement(5229..5837)
                     /locus_tag="SPSINT_RS00585"
                     /old_locus_tag="SPSINT_0121"
     CDS             complement(5229..5837)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SPSINT_RS00585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SPSINT_0121"
                     /product="hypothetical protein"
                     /protein_id="WP_015728572.1"
                     /transl_table=11
                     /translation="MKKTPIVLLFTFAIVLELSPLKSHLVKLLIKSQLLNPYSWSSFLF
                     ITLLFSIILTPIQGVFYSFNNKMQIVNSVYIKNKFKMTEEVIEISKKIKLPTKKQVFLI
                     LLINVITYDVFISILSGFKLNTPLVAFIPIGIIFMISTYFLVYRFCKQRINHKILIFLM
                     SITFSGVILSYVKEEIVIFIVIEIIVFCLYNMILKIIKR"
     gene            complement(5834..6790)
                     /locus_tag="SPSINT_RS00590"
                     /old_locus_tag="SPSINT_0122"
     CDS             complement(5834..6790)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012879.4"
                     /locus_tag="SPSINT_RS00590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0122"
                     /product="insulinase family protein"
                     /protein_id="WP_015728573.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 7.2e-08, bitscore:
                     29.7, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVTKLFYADLDQNLYNLFQNEIKVTYFNKSDSYINQIKAVVNIG
                     GYQYQTGAAHFIEHLKFWKENNNLYDLMNYFGTIMNANTTEYETNFLLYCSKENTVSTL
                     TNFTSYLLNHSYTIEEFNKEKKIILNEVKGYHSILVDENEKLEYVKKIIGDENQINDIS
                     KRYLENLSSICYQKRNIHYYLIGDFSEYIHKSREISMEKIELVVNSDLIIHDYDNTELF
                     LKTLYFHINKFINYYFQNKSLVVNFNKLYYTKKIHDMQLDDFRSYIISYIVNVYEDSDL
                     LIEFLENWKFTRGDFTKIGNLLEDQEKLSILLNEAFM"
     gene            complement(6793..7890)
                     /locus_tag="SPSINT_RS00595"
                     /old_locus_tag="SPSINT_0123"
     CDS             complement(6793..7890)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SPSINT_RS00595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SPSINT_0123"
                     /product="insulinase family protein"
                     /protein_id="WP_015728574.1"
                     /transl_table=11
                     /translation="MDINNAINIYNYHVYINKISGVENFTINQLISEILNEKFKALNDY
                     SIIPYTTTSVLGKDFYNIFYLKTLRNRYVDLDYNYWLNSFYNNFQMSDNECYLALEKLI
                     NKIKKYQLNPMNINKLLVKDKLYPNSLLGSKRLGTIETLNMNQISQELLLQRIPESIYA
                     YNLCISKIKGELNIHKLQNIKYASPFFIPHIVSQKVPPLINGQSINTICYYFESNDEYS
                     KTIYGPMLQGYLTQYGHSILFKKLRIEEFQLYHFEAHFDQETNILFIQYIVDENWKIKV
                     WNLIISEVMDLNINKEEFQTMKIFLSNEYRFKFDKSFGELNHILSLGNKFLQSNNIFKA
                     IQDIKIQDFIKFLDNKKMINIVYEG"
     gene            complement(7877..8668)
                     /locus_tag="SPSINT_RS12740"
     CDS             complement(7877..8668)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SPSINT_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_148220612.1"
                     /transl_table=11
                     /translation="MTISLLLALFLSPFFNKFISLVLLILVLLGVSIFTNFIKFNVKKR
                     KKTTKATVNEISILKWEFKKFFIEKTNVIGIISMFLFLNILNYNIESIDGMTVEFGLKY
                     FLILLIISSISPLNLMFSSDKELRKIATYMPVKKRSIFMAKILVSTLISQFFLSIVVFI
                     NEMLFQEKLGLLYFKVSILLFFLTFLRLKLDMIKPILDYEDKMELWRNPKKYLSLMIVI
                     PPLFVAVALNFYISLVIILSGCLVLELYSQLYGKEDFFGYK"
     misc_feature    8656..8668
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(9138..9836)
                     /locus_tag="SPSINT_RS00605"
                     /old_locus_tag="SPSINT_0125"
     CDS             complement(9138..9836)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="SPSINT_RS00605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0125"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_015728576.1"
                     /transl_table=11
                     /translation="MMSIHLNNLCIWYEPENLIIKNANLYLQKGKIYGLLGKNGSGKTT
                     LINTICGVIPSFSGDIIINNLNISKFNYQARLERFYVPDSPPVISQMTSKQYISFVLNM
                     YQQTLSQEHLLRISKKYNFERYLDIRMNELSFGNKKKAALICSILLDVPIKIFDEPLNG
                     LDIESIDLFVQDLFKMTKEDKCVILSSHLLDIVKKLTPNIIYINNKHCFQFTLNDESDI
                     RKVLSDYDKE"
     gene            complement(10001..10534)
                     /locus_tag="SPSINT_RS13130"
                     /old_locus_tag="SPSINT_0126"
     CDS             complement(10001..10534)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04085.1"
                     /locus_tag="SPSINT_RS13130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0126"
                     /product="SPASM domain-containing protein"
                     /protein_id="WP_015728577.1"
                     /sec_met_domain="subtilosin (E-value: 1.3e-67, bitscore:
                     225.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1e-11, bitscore: 42.3,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.1e-09, bitscore: 35.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWEINDMANLVRKLGASAFSYNWIDDFGRGKKMNQLKLNKLNNLS
                     FAEFEVDVVKNNRDIIPLVPLTKNKANNCGAGWRSIVMDPNGNIRPCALFPKEFVIGNL
                     KEQSYKDVFSSEIVNRLYSLQSPQKSKFCSDECSFKDYCAGCYLKGLNSNKNHRTNYCG
                     WVKNQKLENLVEQI"
     gene            complement(10681..11334)
                     /locus_tag="SPSINT_RS13135"
                     /old_locus_tag="SPSINT_0127"
     CDS             complement(10681..11334)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="SPSINT_RS13135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0127"
                     /product="radical SAM protein"
                     /protein_id="WP_015728578.1"
                     /sec_met_domain="subtilosin (E-value: 1e-74, bitscore:
                     248.6, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.6e-21,
                     bitscore: 73.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.7e-06, bitscore: 23.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-12, bitscore: 45.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQYIFFNDNARLHQLPHGGVIEVKNGMFKDEVFDFEYLDLNSSA
                     FEACTYFDGSMTIIDILKDMCQKYKCDINDHIEWYTNLVNDLYKKNLINLVSNPVKKNL
                     NISGSTEYITPLHAVFEITHKCNLKCAHCYLESSPQVQDTLSLDEFIMIANNMYENGIL
                     TCEITGGEVFVHPNAKEILEFALKKFKKVGILTNGTLLKPDILDLLIKYKKKLL"
     aSDomain        complement(11053..11262)
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SPSINT_RS13135_Subtilosin_rSAM_RRE.1"
                     /evalue="3.00E-23"
                     /identifier="RREFam018.1"
                     /label="SPSINT_RS13135"
                     /locus_tag="SPSINT_RS13135"
                     /protein_end="94"
                     /protein_start="24"
                     /score="73.0"
                     /tool="antismash"
                     /translation="KNGMFKDEVFDFEYLDLNSSAFEACTYFDGSMTIIDILKDMCQKY
                     KCDINDHIEWYTNLVNDLYKKNLIN"
     gene            complement(11412..11543)
                     /locus_tag="SPSINT_RS00615"
     CDS             complement(11412..11543)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020361779.1"
                     /locus_tag="SPSINT_RS00615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="subtilosin A family bacteriocin"
                     /protein_id="WP_037544023.1"
                     /sec_met_domain="Subtilosin_A (E-value: 6.7e-22, bitscore:
                     74.7, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKGIMVSNKGCSTCSIGAACLIDGPLPDFEVMGITGIFGLTS"
     CDS_motif       complement(11514..11543)
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MEKGIMVSNK"
                     /locus_tag="SPSINT_RS00615_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11412..11513)
                     /prepeptide="core"
                     /locus_tag="SPSINT_RS00615_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="31.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCSTCSIGAACLIDGPLPDFEVMGITGIFGLTS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKGIMVSNK"
                     /leader_location="[11513:11543](-)"
     gene            11669..12307
                     /locus_tag="SPSINT_RS00620"
                     /old_locus_tag="SPSINT_0128"
     CDS             11669..12307
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0030552 - cAMP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024934.4"
                     /locus_tag="SPSINT_RS00620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0128"
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="WP_015728579.1"
                     /transl_table=11
                     /translation="MVELLGIKEIIKEKGINNKLCKGEYFQETFEKYIYLVDKGILYVH
                     QDNIDGTTLIYKIIGPDSLFICDNSKYFCGKTEVVFYKMLISSIINDEKTCREYIKLLI
                     NENVKKDMFIRDMLTKDKVCRLLSILVRLANTFGEEEGRMIVIKIKITQEELAQYCGTT
                     RENIARIMKQLKDRKIVDTSSRFIKILSLEEIKQMIPCEGCNSFVCKTF"
     gene            12765..13364
                     /locus_tag="SPSINT_RS00625"
                     /old_locus_tag="SPSINT_0129"
     CDS             12765..13364
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /locus_tag="SPSINT_RS00625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0129"
                     /product="transposase"
                     /protein_id="WP_015728580.1"
                     /transl_table=11
                     /translation="MRQSKKAIQDFKDRKLKYDKQMEIYGDRKSYSKTDHDATFMRMKD
                     DHMRNGELKPGYNLQIATNNQFVLAFGVYSYPGDTRTLKPFLKSIHKLYGDIPEYIVAD
                     AGYGSEYNYTVILDEFEKTPLITYSMYLKEKQRKYKNNPFITANWEYNVIEDYYICPNK
                     KTLHFQSYRKRRDGYGIQRDFKLYACEACVGCSLRS"
     gene            13368..13688
                     /locus_tag="SPSINT_RS00630"
     CDS             13368..13688
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /locus_tag="SPSINT_RS00630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_049770156.1"
                     /transl_table=11
                     /translation="MKQSTKSNTNKSLFKNLTWDYFKAFINKQLSDPKTKHIYQKRKID
                     VESTFVNLKANLGFQRLSVRTQSKVECELGIALMAVNIRKLAKISACFRSLIRKKPSNS
                     KN"
     gene            complement(13755..16016)
                     /locus_tag="SPSINT_RS00635"
                     /old_locus_tag="SPSINT_0130"
     CDS             complement(13755..16016)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166373.1"
                     /locus_tag="SPSINT_RS00635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0130"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_015728581.1"
                     /transl_table=11
                     /translation="MTAIHIHGARQNNLKNIDVSIPKHQLTVVTGRSGSGKSSLVFNTI
                     AAESERLLNETYSSYIQHQLTQYEKPDVDHIENLPVAMVINQKRLGGNSRSTVGTISDI
                     YASVRLLWSRIGTPFVGYSDVFSFNNPNGMCEHCQGLGYVEDIDLNELLDFDKSLNEGA
                     IRFPSFKPDSWRGKRYRYSGLFDNDKKLKDYTKEELDTFLYTEPTRLKNPPSEWPKTAK
                     FEGLIHRFRRSFLINDNFEKKRFLKDVERVVTKQTCPVCHGQRLNQKVLSCKIHGLNIA
                     DFTALTIEETLPFLEQIDSDKATYIIEPLKAQLQALNDIGLNYLTLARETTTLSGGESQ
                     RIKLIRHLNSPLTDLVYIIDEPSVGLHPADIEKINEIMLNIRDKGNTVIIVEHDPDVIK
                     IADHVIDIGPGAGKHGGQITFEGSYAQLKQSDTDTARALTRQHHLKQSAIRDNQAWLHL
                     EHLQHNNLQDVSVAIPKNAQTVVTGVAGSGKSSLIKGGFAKHEDAILIDQKGVHTSNRS
                     NLLTYTGIFDDIREFFSKATGLKKSMFSYNSDGACPNCNGKGVLKTELAFMPDFSQVCE
                     VCGGTRYRPEVLETKVDGYSIADVLALTVEEGLSLFQTHDAIAQTLSALQSTGLGYMTL
                     GQSLDTLSGGEVQRLKLTRYMIEPVTEKIFIFDEPTTGLHEDDIPILQARFDQLIEEGH
                     TVILIEHNITMMTRADWLIDVGPGAGNQGGRILYSGPPAGLKNVAESRTAPHLFGSLSE
                     "
     gene            complement(16065..16838)
                     /locus_tag="SPSINT_RS00640"
                     /old_locus_tag="SPSINT_0131"
     CDS             complement(16065..16838)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220087.1"
                     /locus_tag="SPSINT_RS00640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0131"
                     /product="YibE/F family protein"
                     /protein_id="WP_014614837.1"
                     /transl_table=11
                     /translation="MNAIVILGLILFILMLIFGGKTGLVSFLTLFLNFIILFITVLAIV
                     FGAPIYVVTFIFCIIVSMVNLFLLNRFNTKTLAAFIASTVTTLLMIVAVYLSVHWGHLQ
                     GFTQEEQDETYIFSLNIGIDMEQFMIFTVLLAVIAAVIDLAITISSPVFELHETNPSLS
                     ERELFHSGMRVGREILATSANTIYLALIGGSMTIVFWFFNLHYSFGHMLNAKLFTQEVI
                     TIALGGVAIAVCIPITAMITAWLVKHRHQLPFHLD"
     gene            complement(16835..17944)
                     /locus_tag="SPSINT_RS00645"
                     /old_locus_tag="SPSINT_0132"
     CDS             complement(16835..17944)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614836.1"
                     /locus_tag="SPSINT_RS00645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0132"
                     /product="YibE/F family protein"
                     /protein_id="WP_014614836.1"
                     /transl_table=11
                     /translation="MKQLSKKINTIVIVVSIIVAICAIVFTRLNSSFYHIPLGEVTKIE
                     SHHQEKSVDEQHNQDVKYKDVLQVKLLNTKQQGDTLHVEHRYNASKTEEQAYQPGDKVL
                     LHKGKNQKDTYIIEKKRDTVLVTVISAFFIALLIVGQRIGLQSILSLVINAFAILLAIS
                     LYHAYPQLNLFLLMSLAVMIATILTLWLVIGWSMRTIVTIVSTLLGTFICIFIAWSVIG
                     LTHGQGIKYETMSFLTIQPRTVFLTSVMVGTLGAVMDVAITISSGMYEVLQRSPHISMQ
                     RWVLAGRNIGRDIMGTMTNILLFSYLAGSLPMLLLYLKNGNTLTYSISMNWSLEISRAI
                     TGGIGIVLTIPLTIFLMRIWLSLRGGATR"
     gene            complement(17957..18835)
                     /locus_tag="SPSINT_RS00650"
                     /old_locus_tag="SPSINT_0133"
     CDS             complement(17957..18835)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614835.1"
                     /locus_tag="SPSINT_RS00650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SPSINT_0133"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_014614835.1"
                     /transl_table=11
                     /translation="MELKQLKYFVEVAKREHISEAALELNVAQSAISRHIHNLENELET
                     SLFYRRGRNVFLTAEGKQLLEYAQQILEQVDLTLSQFQTQVQQQQSVFTIGYVDGSIGQ
                     ILPQVLQTIENELSLSLIPTLLDEQETLQALRAQEIDFALTTVTTTDPTFEIVPLVEET
                     YVLYGDLHAPMMNVPNPPLSHILKQPLYLLEPIPTDFKTYLITHADKPVRVLNQEQFAR
                     FILRNQKGFVLAPTYVNLYSQNQQWKKISLSHTDFKKTLRLIYRRDLQKPLRDEVIQII
                     MTHIQQRSVYH"
     misc_feature    19234..19247
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: weak, score: 15.72"
                     /tool="antismash"
     misc_feature    complement(19372..19385)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.06"
                     /tool="antismash"
     misc_feature    complement(19412..19426)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.43"
                     /tool="antismash"
     misc_feature    19651..19665
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    20279..20293
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     misc_feature    complement(20528..20543)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.22"
                     /tool="antismash"
     misc_feature    complement(20587..20606)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.74"
                     /tool="antismash"
     misc_feature    complement(20589..20603)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 22.46"
                     /tool="antismash"
     misc_feature    21170..21185
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
ORIGIN
        1 aaacattatt aattcattgc ggtaatacta cagatgatta tacaggtgca gtgacgacgc
       61 cgatttatca aacgagtacg tatgaacaag atgcgattgg ggagttaaga caagggtttg
      121 aatactcacg tacagcgaac cccacacgtt catcgctcga gtctgtcatt gctgatttag
      181 agcatgggaa ctacggtttc gcattcggtt caggcatggc ggccatcagc gcagttatca
      241 tgttattaga ccaaggcgac cacattattg ttggctctga tgtgtatggc ggctcttatc
      301 gtgcaatgac acgtgtcttc acacgttttg gtattgaatt tgactttgtt aacacgacag
      361 atgttcaaaa tattgaagat aagattaaag ataatacgaa aatgttattt atcgaaacgc
      421 catctaatcc attgctgcgc attacagata tccaagcggt gagtgaaatc ggcaagcaac
      481 acgaactcat gactgtcgtg gataacacat ttatgacgcc atattatcaa acaccgttgt
      541 ctcttggcgc agatattgtt gtacattcag cgacgaaata tttaggtggg catagtgacg
      601 ttgtagccgg acttgtcgca gttaaagacg aaacactcgc agagcgcatt gctttcgtcc
      661 aaaactcaac agggggcgta ttagggcctc aagatagcta cttgcttatt cgcgggatga
      721 aaacattagc tttacgtatg gaacaaatcg aacgtaatgc attagcggtc gtcgaaatgt
      781 tgaatcaaca tgacaaagtg acgaaagtgt atcacccaag ccaaccgtca catttaaact
      841 acgacgtgca tcaagcgcaa gcagatggca caacaggcat catctcattt gaagtagcag
      901 atgtagaaaa agcgaaattc ctagtgagac aaacaaaata tttcacactc gcagaaagtt
      961 taggtgcagt cgaaagttta atttctgtac caagcttaat gacacatgca tcgattccgg
     1021 ctgatattcg tgcaaaagaa ggcattgcag atggtttaat cagattatca ttgggtattg
     1081 aagatacaga tgatcttgta gaagatttaa aacaagcact tgatcaattg taagtgacat
     1141 ggggttgagg gcgtcgtaca gaaacctctt gtgcaacaaa aatttcgtcg taaatgcctg
     1201 cgcaaggctg actcggcttc tcacaagtac aagcattgag aagtcagaca gctactgcgt
     1261 taaacagtag ctagtaccaa agttaaagtc ttcctcaaat ccttatgaat ttcgtttata
     1321 taatcaatca cattcgacag cgtcatgcca tgtctcgttt tgaacatggc atgacttttt
     1381 tgatatacgc aacaaatgaa aatggccctc gtggacactg gatttagtta agacaagtcc
     1441 tggaagcgta caagttaaac caatgcggta tcagtagcgc caaaaagttt tatgtcctat
     1501 cttcatgcac gcactttttt ataagtatga aactaatata tataatcaca atcatatgaa
     1561 aatgttataa ttttgataag ttacagaatt gtttcctagg tttatagtat gatgaaaaac
     1621 catattaagg actttcaaca ggagtcgtga taaatgaata ggatcagagt cgtgtatatc
     1681 gtgaatgttt taaattactt atttttaata gtaggtggac tgatttgtgt gcaattgatg
     1741 ttagcgtttg gtgatttatt attatatttt gaggcaacgt cattagctgc gggcatattt
     1801 tcattgtggc acctaaacgc agacgatgcg aagttacaaa aagtaggctt aatttggttt
     1861 atcatcaatt tacttaatat atttgttttg acacctttaa tcatcttggt attatttttt
     1921 ggcataagtt tttaacgacc gaaatcgcac cttgtaatgt taaaaaggtc gtatcaagct
     1981 ttatcgtgat gcataagttt acttccataa acaatgatga agtggtcaaa tattttacaa
     2041 ttacgaaaga taaataaaag aaatatccga gaaaaatgtc tttatgaata atatgatagc
     2101 tattatttta attctcaaat aagcatgtgt aaatatattt actttctgaa gaccgccatg
     2161 atggtttttg taatcataat gttatataac agacatattt ctacatgata atcggtgtat
     2221 aatataaaac tgtataagaa taatatcttc tattttataa ggagggaaac gaatgcgtaa
     2281 aaagtttatc gcagccgtaa taggaacaac agcagctgcc acagcattat cagcacatgc
     2341 agacgcttca acaacgtatc gtgtacaacc aggtgattca ctttgggcta ttgcaacaaa
     2401 gtataacatc acaatagcac aacttaaaca atataatgga ttaaactcta acttaatctt
     2461 tccgaatcaa gtgttgaagg tttctggtgg tagcagtaca tcacgcacaa caactcatca
     2521 ttcaagccat agcactacgt catcaacagt ctatacggta cgttacggag acactttatc
     2581 aggcattgca gcgcgatatg gaacaacgta ccaaaacatt atgaaatgga acggtttgaa
     2641 caacttcttg attttaccag gtcaaaagtt aaatgtaagt ggtccgtcta caacaccaag
     2701 tcgttccaca gcgaagaagc cggcacctaa aacgtcttca agaaatgcga gttattatac
     2761 agtacaacca ggtgattcac tgtcgttgat tgcgtctaaa tatggtacaa catatcaaca
     2821 tattatggag ttaaatggat taacatcctt cttaattttc ccaggtcaac aattaaaagt
     2881 gagtggatcg gcaccgtcac gtcaaacaac accgacacca agtccaagtt atcaatctcc
     2941 tacattcaac catcaaaact tatacgattg gggtcaatgc acatggtacg tatttaataa
     3001 gcgtaaagag atggggcgcc caatcagtac atactggtgg aatgcaaatg cttgggatga
     3061 taacgctgca cgtgatggtt atacaattaa taaccaaccc gcagtgggat caatcttaca
     3121 atctgactta ggttactatg gtcatgtttc gtatgtagag cgaattaatg ctgatggtag
     3181 tatactcgta tcagaaatga atttcactgc agcaccaggc attctcactt accgtactgt
     3241 accagcgcat cgtgtaagtg ccttcaaata tatccattaa tcaaaaaacg tgagtatacc
     3301 ttttacatgg tgctcacgtt tttatttttt aagacaatag tcgaatgaga aaattttcgt
     3361 catttgaaaa aatcccaaaa agtttgaaat gcatgtcata ttctattaac aaaatggtaa
     3421 caaacatctt gtcgatgatt cttaggtaag gataaagccg ttgagtaaat ccatttcacc
     3481 ttaaaagggt atcgtcatat tcacagaaac ggatgcttta atgattagct ttaaaaactt
     3541 ggttgaagcg aagatacaac gacttgagca tctgggcaat gactactaca taaaaaaggc
     3601 gtgaacagaa atcataatgt ttcatgttca cgcctatatt taatgatttg aaaatgaatc
     3661 aagtcgttac cctacccacg tgtacgaatc gcttggattt tttggatacc actccatact
     3721 tggcgacttg ctgagaagaa agaccacgct tttgtgaatt tgcttttcgc accaagtgat
     3781 aaatagaagc ttaatacgac atctactaag ccaagcccaa ctgaaatata gcttagcttg
     3841 cgattttttg agcgataaat gtaagaattg taaaagtcta caactaatgt tgcgcctgtt
     3901 aaagcagttg aaagcacact taatgatttt ttagattttt tagccattat acttccccca
     3961 atgaatatag tatgatgtca ttcattataa cattactgat aggtcaaaac ccaacatatg
     4021 cactttcctt aaatgattgt taacacgtct tttagataca gcgttgtaga aaaatttcag
     4081 tccaatgacc gaaaaacttt tggatgaaaa tgttatctta atttgttatc attcgagtaa
     4141 ggaacaattt gatatataag ttattataaa ttggaaattt aattcgacaa ttacaaataa
     4201 cataaattcc taatttttag aacagtatcg agagaaagag gagtggtaca catgaatcaa
     4261 gttacaaaaa ttgcagtcgc aacaacttta tcattaggca cattattagg agcaacagct
     4321 ggggcaagtg caatccatgc agatgcacat gccgcaacgg aacagcaaac accttattac
     4381 acatataacg gcttatttaa cttcaaaggg aataaagctt tagaggacaa aaacttttac
     4441 cgcgcattac aacacgataa ctttaaatat gaaggtttaa aagtcggcca gtctacattc
     4501 gctgacgtta aaaaagcggt agggaacgac gtgaaaaaat attatgaaga aaaaggtgtc
     4561 acttactacg agaaaaatga tgtcattttc ggtattgata gcgaaggtaa attggtcaac
     4621 atgacattat taattgaaaa aattaatcac agtgataaat ctgtgcgtga tcatgtgaaa
     4681 caaggcgaaa tttatgatac aaaaacaaca catgtcgcat tttactcagg caactcaatt
     4741 gtgattaaag caaaagagag tcgttaagat tgaggcgtac tttgcccata caacgtcata
     4801 gttaaaaaaa ctccgagact tttcgtgaat agtagacgat aagtctcgga gtttttgagt
     4861 tgatgagagc ttgtttaagt atttcaattt aatgcaatct cgtggccttg tgcagcttct
     4921 gcaatagact tagccagacg ttgtgtattt gcaggcgatt gtaagaaata cagtgtttct
     4981 atattaataa tcaaaacaat tgtgcaacaa cccccctata aagggagttt ttacaaggat
     5041 tatcttatta aagtttaatg aaaatcgcta tttataaatg atgagtaagg attttaggga
     5101 caactataac gtctgtaaga ttcagtttaa atgtatttgt aaaattatta acagtatcat
     5161 tgtaacgttg cctacagtca atgtaattag ttttactgaa aagttatata cagagtagtt
     5221 ctttgtaatt atcttttaat aatttttaaa atcatattat aaagacaaaa aacaataatc
     5281 tctattacta taaatatcac aatctcttct ttcacatatg atagaataac gccagaaaag
     5341 gtgattgaca ttaaaaaaat caggatttta tgatttattc tttgtttaca aaatctatac
     5401 actaaaaaat aagtagaaat cataaaaata ataccgatag gaataaatgc aacgagaggt
     5461 gtgtttaatt taaatcctga gaggatacta ataaagacat catacgttat tacatttatt
     5521 aggagaatta aaaacacttg tttcttggta ggtaatttta tttttttact aatttctatt
     5581 acttcctcgg tcatcttaaa cttatttttt atatatacac tattaactat ttgcatttta
     5641 ttattaaaac tataaaaaac accctgaatt ggggttaaaa taattgaaaa aagcagtgta
     5701 ataaaaagaa aactagacca agaatacgga tttaataatt gggactttat caataatttc
     5761 actaaatgac ttttaagggg agataattct aatactatcg cgaaagtgaa taataataca
     5821 ataggtgttt ttttcacatg aatgcctcat ttaataatat agataacttt tcttgatctt
     5881 caagtaaatt accgattttt gtaaaatctc cccttgtgaa tttccagttt tccaaaaact
     5941 caattaacaa atcagaatct tcataaacat ttactatata agaaattata taacttctaa
     6001 aatcatctaa ctgcatatca tgaatttttt tggtataata taatttattg aaattaacca
     6061 caagactttt gttctggaaa taataattta tgaatttatt tatatggaaa taaagggttt
     6121 tcaaaaacaa ttcagtatta tcataatcat gtataataag atcgctgttt actactagct
     6181 ctatcttttc catgcttatt tctctgcttt tatggatata ttcagaaaaa tcacctatta
     6241 aataatagtg aatatttctt ttttgatagc atattgaaga taggttttct agatatctct
     6301 tagaaatgtc attaatttga ttttcatcgc ctattatctt ttttacatat tctaattttt
     6361 cattttcatc cactaaaatt gaatggtatc ctttaacctc atttaatatt attttcttct
     6421 ctttattaaa ttcttcaata gtgtagctgt gatttaataa gtatgatgta aaattagtca
     6481 aagtagaaac cgtattttcc ttactacagt acagtaaaaa attagtttca tattctgtag
     6541 tatttgcgtt cattatagtg ccaaagtaat tcattaaatc atataagtta ttgttttctt
     6601 tccaaaattt taggtgctct ataaaatgag cagctccggt ttgatattga tatcccccga
     6661 tatttacgac tgctttaatt tgatttatat atgagtcact cttattaaag tatgttactt
     6721 ttatttcgtt ttgaaataga ttgtaaagat tttgatctaa atctgcataa aatagttttg
     6781 taactttcat tttcatccct catatacaat atttatcatt tttttattat ctagaaattt
     6841 gatgaaatct tgaattttta tatcttggat agctttaaat atattatttg attgtaaaaa
     6901 tttatttcct aaactaagaa tgtgattcaa ttctccaaat gatttatcga atttaaatct
     6961 gtattcattt gataggaaga ttttcatagt ctggaactct tctttattaa tatttaaatc
     7021 cataacttca gatataatta aattccaaac ttttattttc caattttcat ccactatgta
     7081 ttggatgaat aggatattag tttcttgatc aaaatgagct tcaaaatgat ataattgaaa
     7141 ttcttctatc cttagctttt taaacaatat tgaatggcca tattgcgtca agtagccttg
     7201 taacatagga ccataaattg tttttgaata ttcatcatta ctttcaaaat aataacaaat
     7261 tgtgttaata ctttgtccat ttattaatgg tggaactttt tggcttacta tatgtggtat
     7321 aaaaaaagga gatgcatatt taatattctg taatttatgt atatttagct ctcctttaat
     7381 ttttgagatg cataaattat atgcatatat agattcgggt attctttgta gtagtaactc
     7441 ttgacttatt tgattcatat ttaatgtttc aatagtccct aaacgtttac ttcctaataa
     7501 tgaatttggg taaagtttgt cttttaccaa taatttattg atattcattg gatttaactg
     7561 atatttttta attttattaa taagtttttc caaggctaag taacactcat tgtcagacat
     7621 ttgaaaatta ttataaaaac tattgagcca atagttataa tctaggtcta cataccggtt
     7681 tcttaaagtt tttagataaa aaatattata aaagtctttt cccaaaacac ttgttgtagt
     7741 ataaggaata attgaataat catttaatgc tttgaatttc tcatttaata tttcagaaat
     7801 caattgatta atagtgaaat tttcaacgcc acttatttta ttgatataga cgtgatagtt
     7861 ataaatattt atagcgttat ttatatccaa aaaaatcttc ctttccataa agttgactat
     7921 atagttctaa tactaaacaa cctgataata taataactag agaaatataa aaatttagtg
     7981 ctacagctac aaaaagggga gggatcacta tcatcaatga taaatatttt ttcggatttc
     8041 tccacaattc cattttatct tcataatcta aaatgggttt tatcatatca agttttaatc
     8101 tcaaaaaagt taaaaaaaac aacaaaatag atactttgaa gtatagtaag cctaactttt
     8161 cttggaatag catttcgttt atgaacacta caatagaaag aaaaaactgt gatattaatg
     8221 ttgaaactaa aattttagcc ataaagatac ttcgcttttt aacaggcata taagtagcaa
     8281 tttttcttaa ttctttatca gatgaaaaca ttaaatttaa tggacttatt gaagaaataa
     8341 ttagtaatat caaaaaatac tttagtccaa actctaccgt cattccatct atactttcaa
     8401 tattgtagtt taaaatattg aggaaaagga acatacttat tattccaatg acatttgttt
     8461 tttctatgaa aaacttttta aactcccatt ttaaaatcga tatttcgttt actgtagctt
     8521 ttgtagtttt ttttctcttt tttacattaa attttataaa attagtaaag atggatacac
     8581 ctaataatac aagaattaaa agcaccaaac ttataaattt attaaaaaat gggcttaaaa
     8641 aaagtgctag aagtaatgaa attgtcacat gtctcttttc acattcatgc aaaagaatgc
     8701 aaataagttg agaagataca attagtagta tgaataatga aaatgtcaaa atgctcccgt
     8761 aaatactgaa tttgccgatt agcaaaacat aaaatggtag tacaagtaaa aaaacaagtc
     8821 ttctcccggt tatctcaacg aaaatatata catttagaat tattaaaacc tttacattat
     8881 taataggcat gtaccctaag agtctatata actcgctttc gcggaaagag ttccagtaaa
     8941 tattagtcaa tataattgag gagaatatga tagataatct tagataattg gaatataaca
     9001 aattgacatt atccaaatga ctttcaatca atttgtattc aaatattaaa agaattgcta
     9061 ttcctagtga atttttaatt atggctctta gattaagttt attgtagtaa tagcaataga
     9121 gtagaattaa atatccatta ttctttatca taatcagata gaacctttct tatatcgctt
     9181 tcatcgttaa gcgtgaattg aaaacaatgt ttattattaa tatatataat attaggtgtc
     9241 agctttttta caatatctaa taaatgagaa gataggatga cgcatttatc ttcttttgtc
     9301 attttgaaaa gatcttgaac aaacaaatct attgactcta tatctaatcc atttaatggt
     9361 tcgtcgaata ttttgatagg tacatctaat aagattgaac aaattaaagc agcctttttt
     9421 ttatttccaa aagagagctc attcattctt atatctaaat acctttcaaa attatatttt
     9481 ttagaaattc tcaataaatg ctcctggctt aaagtttgtt gatacatatt taaaacaaaa
     9541 cttatatatt gtttacttgt catttgagaa ataacagggg gactatctgg tacataaaat
     9601 ctttctaacc tagcttgata attaaatttt gatatattca aattgttaat gattatatct
     9661 cctgaaaaac ttggtataac cccgcatata gtatttatta gcgttgtttt accagatcca
     9721 ttctttccaa gcaatccata aatttttcct ttttgtaagt atagatttgc atttttaatt
     9781 attaaatttt ctggctcata ccaaatacat aagttattta gatgaatgct catcattaga
     9841 tttacctctt ttaaatgttt ttaatatata gataatccct atcaatatga agattactgc
     9901 gaaaacccat tcttgcttaa tggcgaatat tacactagat attaaaaaaa ttatagcaat
     9961 ggttattgta attaagtctc ttttcatgtt ttatctcctt ttatatttgt tctactaagt
    10021 tttctaattt ttggttttta acccaaccgc agtaattcgt ccgatggttt ttgttactat
    10081 taagaccttt taagtaacag ccagcgcagt agtctttgaa gctgcattca tcactgcaaa
    10141 atttactttt ttgtggagac tgcagagagt ataatcgatt tactatttct gaggagaaaa
    10201 cgtctttata tgactgttct tttaagttac cgattacaaa ttcttttgga aatagtgcac
    10261 acggccgaat atttccatta ggatccatga ctattgaacg ccagccagcc ccacaattat
    10321 tggctttgtt tttagttaga ggaactaatg gtataatgtc cctattattt ttaacaacgt
    10381 ccacttcaaa ttcagcaaaa gacaagttgt ttagtttatt caatttcaac tgattcattt
    10441 ttttacctct accaaagtca tctatccagt tataagaaaa ggctgaagct cctagttttc
    10501 ttactaaatt cgccatatca ttgatttccc acatattatc ctcataaata gacattccga
    10561 cccttacaaa aagcccattt tcagaaagtt ttttaatggt tttacaagtc tgattaaatg
    10621 aatttttttt gccacgaaaa ttatcgtgct tttcagggtt aacactatct aatgaaatcc
    10681 ctataacaat tttttcttat atttaattaa taaatcgaga atatctggtt ttaacagtgt
    10741 tccgtttgtt aagataccga cttttttgaa ctttttgagt gcaaattcta atatttcttt
    10801 tgcgtttgga tgtacaaaca cttctccacc agtgatctca catgttagaa ttccattttc
    10861 atacatatta tttgcaatca ttataaattc atctaatgaa agcgtatctt gaacttgagg
    10921 tgaagactct agataacaat gtgcgcattt taaattacat ttatgtgtaa tttcaaacac
    10981 cgcatgtagt ggtgtaatat attcagttga tccgctaata ttaaggtttt ttttaacagg
    11041 attactaacg agattaataa gatttttctt atacaaatcg ttaactagat ttgtatacca
    11101 ttctatgtga tcgttaatat cacatttata tttttggcac atatctttta aaatatctat
    11161 tattgtcatg gaaccatcaa aatacgtaca tgcctcgaaa gcagaagaat ttaaatctaa
    11221 atattcaaag tcgaacactt catctttaaa catgccattt ttcacctcaa ttactccacc
    11281 atgaggtaat tgatgcaacc tagcattgtc attaaaaaat atatattgat tcatttctat
    11341 cccccccctt aataaaaagt acgccgacaa actatgataa atcctatcat tttgccggca
    11401 tacaaacagt gctaagaagt tagtccaaaa attccagtaa ttcccatgac ttcgaagtca
    11461 ggtaatggcc catcaataag acaagcagct ccaattgaac aagtcgaaca acccttgtta
    11521 cttaccataa tgcctttttc cattttggta tcccccttta ttttatttaa ctacaaacac
    11581 attttaatat aaattattca aaagttttgt aacgcatgtt actaaaagta atttaaatgg
    11641 tataattttt tataaagggg ggattgttat ggtagagttg ctagggatta aagagattat
    11701 caaagaaaaa gggataaata ataagttgtg taagggggag tattttcaag agacttttga
    11761 aaaatatata tatctagtag ataagggtat attatatgta catcaagata acatagatgg
    11821 tactactttg atttataaaa tcatagggcc agatagtttg ttcatttgtg ataatagtaa
    11881 atacttttgt gggaaaacag aagttgtatt ttataaaatg cttataagca gcataataaa
    11941 tgatgagaaa acttgtagag aatacataaa attactcata aatgaaaatg tgaaaaaaga
    12001 tatgtttatt agagatatgt taactaaaga caaagtgtgt agattactat ctattctagt
    12061 tagattagct aatacatttg gagaagaaga agggagaatg attgtgataa aaattaaaat
    12121 cactcaagaa gaattagctc aatattgtgg aactacgaga gagaatatcg ctagaattat
    12181 gaagcaatta aaagatagaa aaattgtaga tacgtcttct cgctttataa aaatattatc
    12241 tttagaagag ataaaacaaa tgatcccatg tgaaggatgt aatagcttcg tttgcaaaac
    12301 tttttgattc ttttttgata aactatagcc tgaaaggaag aatttaaaag ctaaagttgt
    12361 gagatgtgaa taataaatta tttaaggaag aggttaataa ttgaagtgta ataatattcg
    12421 gtttaagagc acagttatta gaagaacaac tcattacaga ggatgtcatt tatattgatg
    12481 gcacaaaaat agaagccaat gcgaataagt atacatttca gtggctggct aatacgaagc
    12541 gttttagtca gtctgtcatt gaaaaatcaa cggcattata tgaacaactc gtttctgaag
    12601 agattattcc tgaaatcaag cgtgaatctg gacatgaatt aacaagtgaa gaactgaatc
    12661 aaatagagac gcatttaggt cataaaaatg atgcgctcac gtctgaaatt gaaacaactc
    12721 aagatgtaga gacaagaaaa aaccttagaa aagaaagaag taacgtgaga caaagtaaga
    12781 aggctatcca agattttaag gaccgtaaat taaaatatga caagcaaatg gaaatttatg
    12841 gcgacagaaa aagttattct aagactgatc atgatgcgac tttcatgaga atgaaagatg
    12901 accatatgag aaacggtgag ttgaaaccgg gttacaatct acagatagct accaataatc
    12961 aattcgtttt agcttttggt gtttatagtt atccaggtga tacaagaacg ctcaaaccat
    13021 ttttaaaatc aattcacaaa ttatatggtg acattccaga gtatatcgtg gcagatgcag
    13081 gttacggaag tgaatacaac tataccgtga tactcgatga atttgagaaa acacctttaa
    13141 tcacttatag tatgtacctc aaagagaagc agcgtaaata taaaaacaat ccatttatta
    13201 ctgcaaactg ggaatacaac gtgatagaag attattacat atgtccgaat aagaagacat
    13261 tacatttcca gagttacaga aagagaagag atggatacgg tattcaaaga gattttaaat
    13321 tatatgcatg tgaagcgtgt gtgggctgtt cattacgaag ttaatgtatg aagcaaagta
    13381 caaagtctaa cacaaataaa agtttattta aaaatctaac ttgggattat tttaaagcct
    13441 tcataaataa gcagctttca gatccaaaaa cgaagcacat ttatcaaaag agaaagatag
    13501 atgtggaatc aacttttgta aatctgaaag ctaatttggg tttccaaaga ttatcggttc
    13561 gcacccaatc aaaagttgag tgtgaacttg gcatcgcact catggcagta aatatacgaa
    13621 aactggccaa aatcagtgct tgttttcgtt cgctcataag aaaaaagcca tcaaattcta
    13681 aaaattgaat tttgacgttt tttttcttaa aggagctgaa ggtctatgtc ctagccccat
    13741 actcaatgta ccacttattc cgataaacta ccaaataaat ggggagcggt gcgagattcg
    13801 gcgacgtttt ttaggcctgc aggtggtcca ctataaagaa tgcgtccccc ttgatttccc
    13861 gcaccaggtc caacgtcaat gagccagtct gctcgtgtca tcatcgtgat attgtgttca
    13921 attaagatga cggtatggcc ttcttcaata agttgatcga agcgtgcctg taaaattggg
    13981 atatcatctt catgtaaacc tgttgtcggt tcatcgaaaa taaatatttt ttctgtaaca
    14041 ggctcaatca tgtagcgcgt cagtttgagc cgttgaacct ccccgccaga taaggtgtcg
    14101 agtgattggc cgagtgtcat atagccgagc cctgtcgatt gcaaggcgct taacgtttga
    14161 gcaatggcgt catgtgtttg gaaaagtgac aagccttctt caacggtgag tgctaacacg
    14221 tccgcgatag aataaccgtc gactttcgtt tccaacactt ctggacgata gcgggtccct
    14281 ccgcacacct cgcatacttg cgagaagtct ggcatgaagg cgagttcggt tttgagcacg
    14341 cctttcccgt tacaatttgg acacgcgcca tctgagttat aactgaacat actttttttc
    14401 aatcctgttg ctttactgaa aaactcacga atatcatcga aaatacccgt gtacgttaat
    14461 aaattcgatc ggttggaagt gtgtacgcct ttttgatcaa tgagtatcgc atcttcatgt
    14521 ttcgcaaaac cgcctttaat taaggagctc tttcctgaac cagcgacacc tgttacaacc
    14581 gtttgcgcat ttttcgggat cgcaacagac acatcttgta agttgttgtg ttgcaaatgt
    14641 tctaagtgta accatgcttg gttgtcacga atcgctgact gtttcaagtg atgttgacgt
    14701 gtcaatgcgc gcgctgtatc ggtatcggac tgtttaagtt gtgcataact gccttcaaat
    14761 gtaatctggc cgccatgttt ccctgcgcca ggtccgatgt caatcacgtg atccgcaatt
    14821 ttgatgacgt cgggatcgtg ttcaacgatg atgacggtat tacctttgtc acggatattg
    14881 agcatgattt cgttgatttt ttcaatatct gctggatgta aaccgacact cggttcgtcg
    14941 ataatgtaca cgagatcggt taacggactg ttcaaatgac gaataagctt aatccgttgt
    15001 gactctccgc cagaaagggt cgttgtttca cgtgcgagcg ttaaatagtt cagcccaata
    15061 tcattcaaag cttggagttg ggctttcaat ggttcgataa tataagtcgc tttgtcgctg
    15121 tcgatttgct ctaaaaatgg gagcgtttct tcaatcgtca gtgctgtaaa atcggcaatg
    15181 ttcagtccat gaattttgca gctgagcact ttttgattta agcgttgtcc gtgacagaca
    15241 ggacatgttt gcttggtgac tacgcgttca acgtccttta aaaagcgttt cttttcaaag
    15301 ttatcattaa ttaaaaatga gcgtcggaaa cggtggatta acccttcaaa ttttgcagtt
    15361 ttaggccatt ctgagggtgg atttttcaag cgtgttggct cggtataaag aaacgtatcg
    15421 agctcttctt ttgtatagtc tttgagcttt ttatcattat caaacaaacc cgaatagcga
    15481 taacgtttcc cgcgccaact atccggctta aatgacggaa agcgaatcgc accttcattt
    15541 aaagatttgt cgaaatcgag cagttcattc aagtcgatat cttcaacata accaagccct
    15601 tgacaatgtt cacacatccc attcggatta ttgaacgaaa agacgtctga ataaccgacg
    15661 aaaggtgtgc caatacgtga ccacaatagc cggacggacg cataaatgtc tgaaatggta
    15721 ccgaccgttg agcgcgaatt gccaccgagt cttttttgat tgatgaccat cgcgacgggc
    15781 aagttttcaa tatggtcaac atccggtttt tcatattgcg ttaattggtg ctgaatataa
    15841 ctcgaatagg tttcgttcaa tagtcgttcg gattcagcgg caatcgtatt aaaaacgagg
    15901 gaagacttgc cagatcctga acgcccagtc acgaccgtta actgatgttt cggaatggag
    15961 acgtcaatat tttttaagtt gttttgacgt gcgccatgaa tatgaatcgc tgtcatataa
    16021 attcacctcg ttcacattgt acccgttttc actcgtcttg aagctcagtc tagatgaaaa
    16081 ggaagttgat ggcgatgttt cacaagccaa gcagttatca tagccgtaat cggaatacag
    16141 actgcaatgg cgacccctcc taaagcaatt gtaatgactt cttgtgtaaa taatttggca
    16201 ttgagcatat ggccgaaact gtaatgcaag ttgaaaaacc aaaaaacaat tgtcattgaa
    16261 cctccaatca atgcgaggta aatcgtgttc gcagacgtcg ctaaaatttc tcggccgacg
    16321 cgcatgcctg aatgaaacag ttcgcgttcg gataatgagg ggttcgtctc gtgtaactca
    16381 aatacaggtg agctaatcgt aatcgccaag tcaatcactg ctgcaatgac agcaagtagc
    16441 acagtaaaaa tcataaactg ttccatatca atcccaatat ttaaggagaa gatatacgtt
    16501 tcgtcttgtt cttcttgggt gaaaccttgt agatgacccc aatgtacgga caagtaaacg
    16561 gcgacaatca ttaataatgt cgtgaccgta ctcgcgataa atgcagctaa agtttttgta
    16621 ttaaagcggt tgagtaaaaa caagttaacc atcgagacaa taatacaaaa aatgaaagta
    16681 acgacataaa taggcgcgcc aaaaacgatg gcgagtacag taatgaataa aatgataaag
    16741 tttaaaaata gcgttaaaaa tgaaacgagt cctgttttac cgccaaatat gagcatgagt
    16801 atgaaaagaa tcaaacctaa gatgacaatg gcattcatcg tgttgcacct cctcgtaggc
    16861 ttaaccatat acgcatgaga aaaatggtca atgggatagt taagacgatg ccaatcccgc
    16921 ctgtaattgc ccgggaaatt tctaaggacc aattcatgct aatgctgtaa gtgagcgtgt
    16981 tgccattttt taaataaagt aagagcatcg gtaaacttcc tgcaagatat gagaataata
    17041 aaatgttcgt catcgttccc ataatgtcac gaccgatgtt acgacctgcg agcacccacc
    17101 gttgcattga aatgtgtggc gaccgctgta gcacttcata catcccgctt gaaatcgtaa
    17161 tggcgacatc catcactgcc ccaagcgttc caaccatgac ggaagtaagg aagacggttc
    17221 taggttgaat cgtgagaaag ctcatcgttt catatttaat cccttgcccg tgtgttaaac
    17281 cgatgacact ccatgcgata aaaatacaaa tgaacgtgcc gagtaaagtg ctgacaatgg
    17341 tcacaatcgt acgcattgac caaccaatga cgagccaaag tgttaaaatc gtcgcaatca
    17401 tgactgcgag actcattaat aaaaagagat tcagttgcgg atacgcgtga tacaaactaa
    17461 tggctaacaa aatggcaaac gcgttaataa cgagtgatag gatggattga agtccgatcc
    17521 gttgcccgac aatgagtaat gcaataaaga acgcgctgat gactgtcacg agtacggtat
    17581 cgcgtttttt ctcaataata tatgtatctt tttgattttt tcctttgtgc agtagcactt
    17641 tatcacccgg ttgatacgct tgttcttcag ttttcgaggc gttataccgg tgttcgacgt
    17701 gaagggtgtc gccttgttgt tttgtattta acaatttgac ttgtaacacg tctttatatt
    17761 tcacatcttg attatgttgt tcatctactg acttttcttg gtgatgactt tcaattttcg
    17821 tcacttcacc gagcgggata tgataaaacg aactattcaa acgtgtgaat actatcgcac
    17881 aaatcgctac gatgatactc accacgatga caatggtgtt tatttttttc gaaagttgct
    17941 tcataaatca ttctccttaa tgataaaccg aacgttgttg tatatgtgtc atgatgattt
    18001 ggatgacttc atcacgtaaa ggtttttgta aatcgcgtcg ataaatgagg cgtaacgttt
    18061 ttttgaaatc tgtatgtgac aatgaaatct ttttccattg ttgattttga ctatataagt
    18121 tgacgtacgt tggtgcaagt acgaagcctt tttgattgcg taaaataaag cgtgcgaatt
    18181 gttcttgatt caagacacgg acgggtttgt cggcatgtgt tatcaaatat gttttgaagt
    18241 ctgtaggaat cggttcaagc aagtataacg gttgtttcaa tatgtgtgat aacggtggat
    18301 tcggcacgtt catcattggt gcgtgtaagt ccccatataa gacgtacgtt tcttctacta
    18361 atggcactat ttcaaatgtt ggatccgtcg ttgtgacagt tgtcagtgca aaatcaattt
    18421 cttgtgctcg caacgcttgt aatgtctctt gttcatctaa caatgtagga atgagtgaca
    18481 aggacagctc gttttcaatt gtctgtaaca cttgcggtaa aatttggccg attgagccgt
    18541 ccacataacc gattgtgaag acgctttgct gttgttgtac ttgcgtttga aactgcgaca
    18601 aagtgagatc gacttgctca agaatttgtt gcgcatattc aagcaactgt ttgccttctg
    18661 cggttaaaaa tacgttacgc ccgcgacgat aaaacaatga tgtttcgagt tcattttcta
    18721 aattatgaat atgacggcta attgcagatt gtgcgacgtt caattcgagt gctgcttcag
    18781 aaatatgttc acgttttgcg acttcgacaa agtatttgag ttgtttcaat tccataccat
    18841 tccacctctt acaatttata ttatctcaaa attagataga tttcatctca agtatatatt
    18901 gatgtgataa atcgctttgc tatatagttg aaatattact aaagggaggt gtcagaaatg
    18961 tctaacaatt atttaaattc caaaatcgga ctttatgaca gtcgtgaaga acatgacgct
    19021 tgtgggattg gcttttatgc gaatatgaat aatgaacgtt ctcatgagat tgtcgaaaag
    19081 tctttagaaa tgttacgccg tctcgatcac cgtggaggta tcggtgcaga tggtattaca
    19141 ggtgatgggg caggcattat gacagaagta ccttatcaat atttctcaga agtcactgat
    19201 tttgatttgc cgactgaagg tgactatgcg gtaggtatgt tgtttgccaa cgtcatgatt
    19261 tctgacacaa aacatgcagc ggtaatggca tcaatttttg aaggagaagg gttgcgtatc
    19321 atcggtgatc gtcaagtacc ggtcgacgtg acgtgtctcg cgccgcatgt agcagaaacg
    19381 atgcctgtca ttcaacaagt cttcgtcgta aatgagagcg ctcaagactt taagcgtgca
    19441 ttgtaccttg cgcgtaagca aatcgaaaaa tatggtgaaa gtgcacagtt agatttatat
    19501 tttacgagtt tatcgacacg taccattgtt tataaaggat ggttgcgttc agaccaaatt
    19561 aaatcattat atgtcgattt acaacagccg tcatacgtat cgaaatttgg ttcggtacac
    19621 tcgcgtttta gtacgaatac atttccgagt tgggagcgtg cacatccaaa tcgcttgctc
    19681 gtgcataacg gtgagattaa tacgattcaa ggtaatgtga actggatgcg tgcccgtcaa
    19741 cgtcgcttaa ttgaaacgat tttcggcgag gcgcaacata aagtccatca aatattggat
    19801 gaatcgggca gtgactcggc tattgtggat aacgcactag agtttttaag tttagcgatg
    19861 tcgcctgaac aagcagcgat gttactcatt ccagaaccgt ggttgtataa cgaaagtaac
    19921 gatccgaaag tacgcgcatt ttacgaattt tatagctatt taatggagcc gtgggatgga
    19981 ccgaccatga tttcattctg tgatggtgac aagttagggg ctttaaccga tcggaatggc
    20041 ttgagaccag gccgttatac aattacgaaa caaaatgaaa tcgtcttttc atcagaagtc
    20101 ggcgtcgtgg atgtagacga agcagatgtt gtatttaaag ggcaactgaa tccaggtaag
    20161 ctattgcttg tcgattttaa tcaacataag gttatcgaaa accatgaatt aaaaaccgcg
    20221 attgcagagc agcaacccta tttggaatgg ttggaaacgt atcaacacaa gctcgattta
    20281 gaagcggtct catatgcggg tggacctgtc gctgtagacc atgttcttaa aatgcaacaa
    20341 cgctttggct atacgaaaga agagttggac aagtatttaa ctgaactcgt gacaggtggc
    20401 aaagatccta ttggggcaat gggttacgac gcaccacttg ccgtactcag cgaacgacct
    20461 gaatcactgt ttaattattt caaacaactc tttgcacaag taacgaaccc accgattgat
    20521 gcatatcgtg aaaaaattgt aacgagtgaa ttgagttatt taggtaaaga aggcaacttg
    20581 ctggaaccag ggccggatgt cctcaagcgg gtacaactga aacatcccgt gttgacacca
    20641 gcacaattag acgtcatcgg acaagaaggc tttacggtag cagagttttc gacaggttac
    20701 acaggtggat taaaagaagc gctagacaac ttaggggaag tggtcatcaa agcggtacgt
    20761 caaggggcag aaatcatcgt gttgaatgat agtgacgtca ccgaagcaga ccagtatgcg
    20821 atgccgattt tattagcggt gagtcatatt catcaattat taattcgtga aaatttacgg
    20881 atgcaaacga gcattgtcgc aagttctggt gaaacacgtg aagtgcatca ccttgcttgt
    20941 ttagtcggtt acggtgcgaa tgcagtcgtt ccgtatcttg cacaacaaac gattgcgcaa
    21001 ttgacagagc acggtagatt agacggtgta gtagccgata acgtcgcgcg ttacaacgcc
    21061 attttatcag agggtctgat taaagtaatg gcgaaaatgg gtatctctac ggttcaaagt
    21121 tatcaagggg cgcaaatctt tgaagcggta gggttatcag aagcagtgat taacgattat
    21181 tttacgggca caccttctaa attatcgggc atctccattg aaacattaga cgctgaaaac
    21241 aaggcgcgcc aaacgattaa aggtgacacg ttagacccag gaagcacatt ccaatggcgt
    21301 caacaaggtc aacatcatac attcaatcca acaacgatac gattacttca acatgcgtgt
    21361 cgcgacaatg attatgcgca gtttaaagca ttttctaaag tggcgaacga tcaaacgagc
    21421 agccatattc gagacttatt tgctttcaaa tcacaacagg ccatcgatat tgcacaagtc
    21481 gaaccggttg aggaaattgt gaaacgcttt aaaacgggag cgatgagtta tgggtcaatt
    21541 tca
//
