LOCUS       NC_015953              20978 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. SirexAA-E, complete sequence.
ACCESSION   NC_015953
VERSION     NC_015953.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Streptomyces sp. SirexAA-E
  ORGANISM  Streptomyces sp. SirexAA-E
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7414440)
  AUTHORS   Takasuka,T.E., Acheson,J.F., Bianchetti,C.M., Prom,B.M.,
            Bergeman,L.F., Book,A.J., Currie,C.R. and Fox,B.G.
  TITLE     Biochemical properties and atomic resolution structure of a
            proteolytically processed beta-mannanase from cellulolytic
            Streptomyces sp. SirexAA-E
  JOURNAL   PLoS One 9 (4), e94166 (2014)
   PUBMED   24710170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Streptomyces sp. SirexAA-E
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2011) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. SirexAA-E
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            environment                       :: Soil, Terrestrial
            num_replicons                     :: 1
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly                          :: Newbler v. 2.3 (pre-release)
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi05895
            Funding Program                   :: DOE-GLBRC 2008
            Source of Isolate :: Cameron Currie (currie@bact.wisc.edu)
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method                   :: Newbler v. 2.3
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000177195.2-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 02:12:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,619
            CDSs (total)                      :: 6,532
            Genes (coding)                    :: 6,385
            CDSs (with protein)               :: 6,385
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 61 of 147
            Pseudo Genes (incomplete)         :: 120 of 147
            Pseudo Genes (internal stop)      :: 8 of 147
            Pseudo Genes (multiple problems)  :: 39 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5143472
            Orig. end                         :: 5164450
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002993.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086644
            Source DNA and organism available from Cameron Currie
            (currie@bact.wisc.edu)
            Contacts: Cameron Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20978
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="15"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20978
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20978
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10978](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10978)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(148..157)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(774..786)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.41"
                     /tool="antismash"
     gene            1001..1657
                     /locus_tag="SACTE_RS23090"
                     /old_locus_tag="SACTE_4648"
     CDS             1001..1657
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127682.1"
                     /locus_tag="SACTE_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4648"
                     /product="response regulator transcription factor"
                     /protein_id="WP_014048432.1"
                     /transl_table=11
                     /translation="MTEEPATRRVITLALVDDHPVVRDGLRGMFSSAPGFEVLGEAADG
                     VAAVELVRRVDPDVVLMDLRMPGGGGVAAIAELTRLGARSRVLVLTTYDTDSDTLPAIE
                     AGATGYLLKDAPREELFTAVRAAADGRTVLSPAVASRLITRVRTPAAPGGEALSTRERE
                     VLALVAKGTSNREIAAVLFISEATVKTHLTHVFAKLGAKDRAAAVALGYERGILG"
     gene            complement(1850..3970)
                     /gene="glgX"
                     /locus_tag="SACTE_RS23095"
                     /old_locus_tag="SACTE_4649"
     CDS             complement(1850..3970)
                     /EC_number="3.2.1.196"
                     /GO_function="GO:0004133 - glycogen debranching enzyme
                     activity [Evidence IEA]"
                     /GO_process="GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992326.1"
                     /locus_tag="SACTE_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4649"
                     /product="glycogen debranching protein GlgX"
                     /protein_id="WP_019992326.1"
                     /sec_met_domain="CBM_48 (E-value: 2.4e-18, bitscore: 64.7,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 9.8e-15, bitscore:
                     53.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLGARFRVGPDGVAGTNFALWAAGAEAVELCLFDAAGRETRLPL
                     TELTHEIWHGFVPGVGAGQRYGYRVHGRWDPWTGARWNAAKLLLDPYARAVDGTFTLPP
                     EVYGHVRDWPDQHVADTVRDDRDSAPFVPKGVVVHDDDDWADDRRPKTPWADTVIYELH
                     VRGFTRLHPGIPPELRGTYAGLAHPAAIGHLRRLGVTAVELLPVHQFAHEDHLLRRGLR
                     NYWGYNSIGYFAPHADYAASGTAGGQVGEFKQMVHALHDAGIEVILDVVYNHTAEAGEL
                     GPMLSLRGIDNRGYYRLQDDARRYADYTGCGNTLHVVQPHVLRLITDSLRYWVTEMGVD
                     GFRFDLAAALARSMHDVDMLSPFLAVIAQDPVLRRVKLIAEPWDVGNGGYQVGAFPPLW
                     TEWNDRYRDAVRDFWRGALPDVRDLGYRLTGSSDLYAWGGRRPYASVNFVTAHDGFTLR
                     DLVSYEHKHNEANGEDNRDGTDDNRAWNCGAEGESDDPDVTALRRRQLRNLLTTLLLST
                     GVPMLVAGDEMGRTQGGNNNAYCQDNETGWLDWSLLEQPEWRELTELTSRVLALRHTHP
                     VLRRRAFFAGTPQAPDGLRDLAWFTPEGTEMTEGDWYAPAATLALYLSGRDIPGRDATG
                     GQVTGDSFLAVLHAGHAPCEVRLPGPPWATAYELVLDTSREDQSAAPGTVRLGGTVLSV
                     PGRSVLLLRVRE"
     gene            4241..5461
                     /locus_tag="SACTE_RS23100"
                     /old_locus_tag="SACTE_4650"
     CDS             4241..5461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378972.1"
                     /locus_tag="SACTE_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4650"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_014048434.1"
                     /transl_table=11
                     /translation="MNHEAKRARAGSAAVLTWAGLFTVLAVLTGCTQATSFFGDGRAPG
                     DAIRIVPKDGAENVGADDRIEVTVPDGRLERVKVTRIEDAEQEEVPGKIAGNGRSWAPE
                     DKEYRLGLAGKYSVEAVAVDGDGRRSARSTTFTTLVPKDRFIGYFKPENRSTVGTGMIV
                     SFDFNRPVRNRAAVEKAIRITTEPQVEVVGHWFGTERLDFRPAQYWEPGTEVTVDVGLR
                     DVEGAPGVYGSQRKKVTFRVGRSQTSVVDAAAHTMEVRRDGEVVSTVPITAGAEKTTTY
                     NGKMVVSELHEVTRMDGRTVGFGGEYDIKDVPHAIRLTKSGTFLHGNYWESPDIFGSDN
                     TSHGCIGLRDIKGGSSDTPAGWFFERTLVGDVVEVVNSTDKTVAPDNGLSGWNLGWPQW
                     KAGSALR"
     misc_feature    complement(5544..5559)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            5676..6932
                     /locus_tag="SACTE_RS23105"
                     /old_locus_tag="SACTE_4651"
     CDS             5676..6932
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457224.1"
                     /locus_tag="SACTE_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4651"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_014048435.1"
                     /transl_table=11
                     /translation="MNGLPISGASAGAGRGRDVRGAHGPLALVLGALLLLVTACGGSGA
                     AADKGEDAKAAPRKTADTSASQAVVTIAPKDGADGVATSGELQITAARGKLSTVKVADP
                     KGNEVAGVIAADGLSWVPDRHLAAATKYAVHAVAEDEKGRQSAKDTTFTTLVPKNTFIG
                     QYTPEDGSTVGVGMPVSIHFTRGITDPEAVEKAIKVTAEPAVEIEPHWFGNDRLDFRPE
                     KYWAAGTKVTLRLDLDGVEGRPGVYGKQAKTVSFTVGRSQVSTVDARSHRMKVVRDGKQ
                     IKDIPISAGARPTTTYNGQMVISEKLEVTRMDGDTVGFGDEYDIKDVPHAMRLSTSGTF
                     IHGNYWGPSSIFGSTNTSHGCVGLRDVRGGRDGKAPAAWFFDNSLIGDVVVVKNSDDKT
                     IQPDNGLNGWNMDWAEWTE"
     misc_feature    5686..5702
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            7013..7780
                     /locus_tag="SACTE_RS23110"
                     /old_locus_tag="SACTE_4652"
     CDS             7013..7780
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (5-246). E-value: 8.6e-76. Score:
                     246.4. Matches aSDomain:
                     nrpspksdomains_SACTE_RS23110_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127686.1"
                     /locus_tag="SACTE_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4652"
                     /product="enoyl-CoA hydratase-related protein"
                     /protein_id="WP_014048436.1"
                     /transl_table=11
                     /translation="MTVTLEVRDNVGTIRLDRPPMNALDVAVQDRLRELADEAARRDDV
                     RAVILYGGEKVFAAGADIKEMQAMDHTAMVKRSKGLQDSFTAVARIPKPVVAAVTGYAL
                     GGGCELALCADFRIAADTAKLGQPEILLGLIPGAGGTQRLARLIGPSKAKDLIFTGRQV
                     KADEALTLGLVDRVVPAAEVYERAHAWAARLAKGPALALRAAKESVDAGLETDIDTGLT
                     IERTWFAGLFATEDRERGMRSFVEEGPGKATFR"
     aSDomain        7028..7750
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SACTE_RS23110_ECH.1"
                     /evalue="8.60E-76"
                     /label="SACTE_RS23110_ECH.1"
                     /locus_tag="SACTE_RS23110"
                     /protein_end="246"
                     /protein_start="5"
                     /score="246.4"
                     /tool="antismash"
                     /translation="EVRDNVGTIRLDRPPMNALDVAVQDRLRELADEAARRDDVRAVIL
                     YGGEKVFAAGADIKEMQAMDHTAMVKRSKGLQDSFTAVARIPKPVVAAVTGYALGGGCE
                     LALCADFRIAADTAKLGQPEILLGLIPGAGGTQRLARLIGPSKAKDLIFTGRQVKADEA
                     LTLGLVDRVVPAAEVYERAHAWAARLAKGPALALRAAKESVDAGLETDIDTGLTIERTW
                     FAGLFATEDRERGMRSFVE"
     gene            8044..8559
                     /locus_tag="SACTE_RS23115"
                     /old_locus_tag="SACTE_4653"
     CDS             8044..8559
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060059.1"
                     /locus_tag="SACTE_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4653"
                     /product="ATP-binding protein"
                     /protein_id="WP_019992323.1"
                     /transl_table=11
                     /translation="MMGGMAGLEGVEQPRPRSSAAAARWSTAADDEQAFKELELFGNPT
                     EEEVRLPSRPQSAATARRITSCVMLRQWQLSPQTAEHGVLLVSELVGNAVRHTGARVFG
                     LRMLRRRGWVRIEVRDPSRGLPCLMPVREMDVSGRGIFLVDKLSDRWGVDLLPRGKTTW
                     FEMRTTDR"
     misc_feature    8798..8807
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.41"
                     /tool="antismash"
     gene            8946..9791
                     /locus_tag="SACTE_RS23120"
                     /old_locus_tag="SACTE_4654"
     CDS             8946..9791
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048438.1"
                     /locus_tag="SACTE_RS23120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4654"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_014048438.1"
                     /transl_table=11
                     /translation="MDGRRTVVLRRTALRAAAGALLTGAATGCADGGRGAHAPQGPRSA
                     PEGPRSAPEPDGARQADGARQTEGPGRMAAAPRRFASLPGQIEHGSRARPRVALTFGGE
                     GDPALALRVLADAERAGARLTVLAVGDWLDAHPEMARRILDGGHELGNHTQSHPDVNAL
                     DEARAYAEITDCARRLRRLTGSIGTWFRPSRSRRATPLVEDLARRAGYPHVLSYDVDSL
                     DLTSPGVAAVTRKVTGELRNGSVVSLHFGTRDTVAALPLLLTEIDRRGLRAVTATELFT
                     "
     gene            complement(10001..10978)
                     /locus_tag="SACTE_RS23125"
                     /old_locus_tag="SACTE_4655"
     CDS             complement(10001..10978)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492272.1"
                     /locus_tag="SACTE_RS23125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4655"
                     /product="terpene synthase family protein"
                     /protein_id="WP_019992322.1"
                     /sec_met_domain="T1TS (E-value: 2.4e-63, bitscore: 213.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFQSAGCNPGMEETKAAAWRWAEENDLDLSPVARKKMLRTRPEL
                     WISLIFPRASQEDLDLFCQWLFWAFLVDDEFDDGPAGRDPRMCEKSIARLVDVLDGEKP
                     LVPMEHALEGLRDRTCRDRSPAWNRQFRRDTAAWLWTYYAEAVERAAGQVPSRADFARH
                     RRDSVAMQPFLDLHEITAGIDLPESARSLPAYIALRTAVTDHSGLCNDICSFEKEAVLG
                     YEHNAVRLIQRDRRTTLQEAVDEAGIQLARIAERVQRAERELVEEIAAAGIEGSTRAAL
                     ECCVRDYRGLVRGDFDYHARAERYTRPDLVEVDRRDTLSRHFAA"
     misc_feature    complement(10981..10998)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    complement(11175..11189)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(11413..11811)
                     /locus_tag="SACTE_RS23130"
                     /old_locus_tag="SACTE_4656"
     CDS             complement(11413..11811)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048440.1"
                     /locus_tag="SACTE_RS23130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4656"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_014048440.1"
                     /transl_table=11
                     /translation="MPVVVFRIDRRSGVATYLQIVRQVEQALRMGALEEGDRLPTAAQV
                     AATTKVNPNTTLKAYRELERAGLAEVRQGAGTFITRSLAQPGSGPDWPLRSALNEWMHQ
                     ARAEGLGGAEVQELFRASFEEAYGDGSG"
     misc_feature    complement(11861..11874)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    11871..11887
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            complement(11893..12861)
                     /locus_tag="SACTE_RS23135"
                     /old_locus_tag="SACTE_4657"
     CDS             complement(11893..12861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048441.1"
                     /locus_tag="SACTE_RS23135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4657"
                     /product="ABC transporter permease"
                     /protein_id="WP_014048441.1"
                     /transl_table=11
                     /translation="MSTTSTDASTGRATPRRMVRGLNWLVLRQHRAALLCLLGLTLLVS
                     LWIVYQRAQLIDLLDAAGRPEEGAGQPVTGRQYSLLTMLLGALPVVLAVFLGAPLVAAD
                     TEQGTAQLVTTQSVTRRRWLVAKLGWCFGATLLACAVLSALFTWWWRPYRSVLSISWLD
                     AEVFDNTGPVLPALALFLTAAGVTIGVLLRRVLASMVVTFVFAVAVETAWSMIRQNLAP
                     TRMVTYPLDSELPARLSESYEVERWVGTADGKLYGWGSCVEATEKAQEACLAQKGIVDN
                     VIEYLGQDQMAAMQWTGAGILLAGTAALTAFVVLRSARRPL"
     gene            complement(12858..13802)
                     /locus_tag="SACTE_RS23140"
                     /old_locus_tag="SACTE_4658"
     CDS             complement(12858..13802)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048442.1"
                     /locus_tag="SACTE_RS23140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4658"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014048442.1"
                     /transl_table=11
                     /translation="MTGKSTSTGPGGTWALEARGLGRRYRRGWALRDCSFRLPAGRICG
                     LVGPNGAGKSTLLGMATRQVEPTEGELRLFGVPVSDREVMPRFAFLGQDKPLFKRFTVA
                     ETLRMGAELNPDWDMAAAERIVRAGNVPPHAAVGTLSGGQRTRVAFALAFGKRPDLLLL
                     DEPMSDLDPLARHEMSTLLMAEAVERGTTVMMSSHMLTELEDMCDYLLVLAEGRVRMAG
                     DADALVPAHALVTGVTQDGSLPAALTRHTVIESRVHGRQFQAMVRPQGPLTGDWRVSEP
                     SLEEVLLAHLRSPDAPALYTPGAAVDPQEARTV"
     gene            complement(14138..14530)
                     /locus_tag="SACTE_RS23145"
                     /old_locus_tag="SACTE_4659"
     CDS             complement(14138..14530)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048443.1"
                     /locus_tag="SACTE_RS23145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4659"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_014048443.1"
                     /transl_table=11
                     /translation="MTHGTNLLLTVRHPADSLAVVTVSGELDVDTAPELRTKATELIGQ
                     GCPHVVLDMAPVEFCDSSGLNALIAIVQHAHERGGSLSVAAAPDQLTRLLDMTGVGDLM
                     PVHAHVDEAVAHLGRTATATEDTPDA"
     gene            14937..15434
                     /locus_tag="SACTE_RS23150"
                     /old_locus_tag="SACTE_4660"
     CDS             14937..15434
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048444.1"
                     /locus_tag="SACTE_RS23150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4660"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_014048444.1"
                     /transl_table=11
                     /translation="MGLNPEPDHRSRDAAHEGSEVIELLEVLWERGREAVPTGPVSPSQ
                     LRVLYTLDRDEGINLRMLAEALGSASPSVSRLCDRLQATGFVERAPSPVSRRELELRLT
                     SHGKAYLVDLRMRREQVLMSTIDAMPPKARRALLEGLRGFRSAAAAAGQDDGAARPLRS
                     TG"
     gene            complement(15447..16634)
                     /locus_tag="SACTE_RS23155"
                     /old_locus_tag="SACTE_4661"
     CDS             complement(15447..16634)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321503.1"
                     /locus_tag="SACTE_RS23155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4661"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_014048445.1"
                     /transl_table=11
                     /translation="MDRIAAVERALRNAAPDLLLDVVTAALREQYDVQSVELRLADYGV
                     TTLQVVAEVPLVEPVPIHDSPQGRAFGAQEPYVEPRVGDGPVTVHLPVTVRGDRMGVLT
                     VTTSDDRTRADLREMQGVCEALGHEILVAERDTDLYLLARRATRLTLAAEMQWQLLPGR
                     SVTRPEFSLGAHLEPAYAIFGDNFDWSVSAHHLTLTVTNGMGKGMEAALLTNLVVNALR
                     NARRAGLDLPGQASLADQAVYAQYRGALHASVLLLRFDLATGEVEAVDAGSPRMWRLRG
                     RGVESVAFDAQLPLGMFEETVYVSEHLRVEPGDRLLVSSDGVYESASAAGERYGERALA
                     RSLSAHRFLPSAQVPLAVLRDLKEYRGGATPLDDDALVVCLDWYGRQAPNGDTQA"
     misc_feature    complement(16637..16652)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.83"
                     /tool="antismash"
     gene            16939..17829
                     /locus_tag="SACTE_RS23160"
                     /old_locus_tag="SACTE_4662"
     CDS             16939..17829
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158118.1"
                     /locus_tag="SACTE_RS23160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4662"
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="WP_014048446.1"
                     /transl_table=11
                     /translation="MSLISERAAETTASDEVSAPDGGAASVGELPWIEDAGKIAPKDAR
                     ELSTLFFAQLQVLEEGTHEYQYARNTLIEMNISLVRFAARRFRNRGSGDMEDITQVGIV
                     GLIKAIDRFELSREVEFATFAVPYIVGEIKRFFRDTTWAVHVPRRLQELRVELAKAKEE
                     LAVRLDRDPTVKELAEYLGLTEDEVVEGIVASNGYTAGSLDLPTDANEATATATRTFAD
                     ILGEPDAAMETVENLHALAPLLEELDDRERRIIEMRFGQEMTQAQIGAELGISQMHVSR
                     LLSRTLGKLRTGMFA"
     gene            17943..18197
                     /locus_tag="SACTE_RS23165"
                     /old_locus_tag="SACTE_4663"
     CDS             17943..18197
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048447.1"
                     /locus_tag="SACTE_RS23165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4663"
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_014048447.1"
                     /transl_table=11
                     /translation="MLMAHPVILRGLVDRYHELLAQDSAQGSQETRCQLEDVTYTLCVS
                     TGTRTADEALAVAEQQLTAALRDPALRVGRPLDAQLTAS"
     gene            complement(18258..18452)
                     /locus_tag="SACTE_RS34410"
                     /old_locus_tag="SACTE_4664"
     CDS             complement(18258..18452)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SACTE_RS34410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SACTE_4664"
                     /product="hypothetical protein"
                     /protein_id="WP_019992319.1"
                     /transl_table=11
                     /translation="MSGTEKSAPMAEGLGKKPGGGDVAGSVKAGPDLPERWADRSKTPF
                     TASSGSHVSVWRNAGSVSR"
     misc_feature    18410..18424
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(18513..19436)
                     /locus_tag="SACTE_RS23175"
                     /old_locus_tag="SACTE_4665"
     CDS             complement(18513..19436)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048448.1"
                     /locus_tag="SACTE_RS23175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4665"
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_014048448.1"
                     /transl_table=11
                     /translation="MTTAAPPVLVTGATGRQGGATARALLAQGTPVRALVRDPDAPRAR
                     AVEALGAHLFVGDLTEPATLTAAVDGVRAVFSVQMPAYTGQGFDFAGEVAQADNLMTAA
                     RAAGVEQFVQSSTSGVGRHVEAPGWAEGRWAIMEAPLGTKAAIQDRLRELDFPYWTLIK
                     PSFFMENFEPSMRFYFPRGVEGGLVTVVKPGTHLALVAAQDVGRAAAAALSAPVEFHRV
                     ELELAGDHLTMTAIAEILSRALGVPLTAPDMTEEQARAAGMGDMGATHAFMDAVGQPAR
                     PEFARALGIEVTGFEQWAREHLGPAA"
     gene            19540..20106
                     /locus_tag="SACTE_RS23180"
                     /old_locus_tag="SACTE_4666"
     CDS             19540..20106
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048449.1"
                     /locus_tag="SACTE_RS23180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4666"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_014048449.1"
                     /transl_table=11
                     /translation="MTGQRSDARRNYAHILAVAEAEVATQGAQASVERIARVAGVGSAT
                     VRRHFPTRKALLEAVFKQRVLVLCERAQTLRDDENDSRAALVEWLRELLAYSLAARGLA
                     DVLSYEPLQDEATQDSCAGVIGAAGASLLRRAVDDQAVRADVTIDDLLTLIVGIALATE
                     NYTDPAAHAERAFRLAVAGLDATRT"
     gene            complement(20154..20609)
                     /locus_tag="SACTE_RS23185"
                     /old_locus_tag="SACTE_4667"
     CDS             complement(20154..20609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048450.1"
                     /locus_tag="SACTE_RS23185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4667"
                     /product="hypothetical protein"
                     /protein_id="WP_014048450.1"
                     /transl_table=11
                     /translation="MGTNGHTVRYVRFQSPHRNERSTFTGVFGLVNTLARTGRLTAGQE
                     AFRRANNRWYDAAYPDPSTVDPAVYDDTVNPGAAAWFKPTATHLIERVPGYLGLLAAHG
                     VACRKVVSTAPGRIVYEDDVQIVVVPFGPEAGEDPVSGRSTSSESGS"
     misc_feature    complement(20760..20780)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    complement(20830..20845)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
ORIGIN
        1 cttctccgtc tacgccatcc tcggctactt cgacgcgggc accctgctgc cgaagcgctt
       61 cgtgcgcgcc ggactcctgt tcaccgccgc caccatggcc ggctcccagt ccggcagcgg
      121 gctgccgccg gtctccctcc tcaactgggc cgccttcctc gcgctcttcg cgctgcacgc
      181 ggcactcgcg ttcctcttcg gtgacctcga cgcgcgggag gcggcgaagg cccgccgcca
      241 gaaggagacc atcaccgagc tggaacgcac caacacccgc ctcgaacggg ccctcgccga
      301 gaacgccacc ctgcacgccc aactgctcct ccaggcccgg gaggccggga tcgccgacga
      361 acgccgccgt ctcgcggccg agatccacga caccctcgcc caaggcctgg ccggaatcat
      421 cacccagctc caggccgtca cctccaccgc cgggagcgac cccgcgctgg cccggcagca
      481 cctcgaccgg gcgtcggcac tcgcccggca cagcctcggc gaggcccgcc gttccgtgca
      541 caacctggtg cccgcggcgc tggaggacga cgacctgccc caggcgctcg ggaagacggt
      601 ggccgcatgg gccggacggc acgcggtccg ggccgagttc acggtcacgg ggaccgtcga
      661 acccctccac gacgaggtcg gggcgaccct gctgcggatc gcggaggagt ccctcgccaa
      721 cgcggcccgg cacgcgtcgg cgacccgcgc cggggtcacg ctctcctaca tgggtgacga
      781 ggtcaccctg gacatacgcg acgacggacg cggcttcgac ccgaccgcgc tcccgccgta
      841 cagcggcgcg ggcggcttcg gcctgggcgg gatgcgggcc cgcgccgaac ggatcgcggg
      901 cacggtcacc gtggagaccg gccccgggct gggcaccgcc gtctccgcca gggtccccct
      961 ggtccggcgc ggatgacggg acgctaccgt gaggcacgac atgactgagg aaccggccac
     1021 ccgacgcgtc atcaccctcg ccctcgtcga cgaccatccc gtcgtacggg acggcctgcg
     1081 cgggatgttc tcctccgccc ccggcttcga ggtgctcggc gaggcagccg acggggtggc
     1141 cgccgtggag ctcgtgcgcc gggtggatcc cgacgtcgtg ctgatggacc tgcggatgcc
     1201 gggtggcggg ggagtggccg ccatcgccga gctcacccgg ctcggcgccc ggtccagggt
     1261 gctcgtgctg accacgtacg acaccgactc cgacacgctc cccgcgatcg aggccggcgc
     1321 gaccggttat ctgctcaagg acgcgccccg cgaggagctc ttcaccgccg tacgcgccgc
     1381 cgccgacggg cggacggtgc tctcaccggc cgtcgcctcc cgtctgatca cccgggtacg
     1441 gacccccgcg gcccccggcg gggaggcgct gtccacccgg gagcgcgagg tgctcgccct
     1501 cgtcgccaag ggcacatcga accgtgagat cgcggccgtc ctgttcatca gcgaggcgac
     1561 cgtgaagacc cacctcaccc atgtcttcgc caagctgggc gccaaggacc gcgccgccgc
     1621 cgtggccctc ggctacgagc gcggcatcct cggctgagac cccgcgcccc ggccagggcg
     1681 tgttccggaa gtcccgcctg tccggcgacg cctggcatgc accctcgccg cgttgtcggg
     1741 atcaccccgg tacatccggt accggggcgg ccctccgccg tgcgatcgca cgcaccggac
     1801 gccgccggac ccgccctccg ggcggacggc gccacttccg agacacgccc tactcccgca
     1861 cccgcagcag cagcaccgag cggcccggga cgctcagcac cgtccctccg aggcggaccg
     1921 ttccaggggc ggccgactgg tcctcccgtg aggtgtccag gaccagttcg tacgccgtgg
     1981 cccagggcgg ccccggcagc cggacctcgc acggggcgtg cccggcgtgc aggaccgcca
     2041 ggaagctgtc gccggtgacc tgcccgcccg tggcgtcccg gccggggatg tcccgccccg
     2101 agaggtacag cgcgagcgtg gcggccgggg cgtaccagtc gccctcggtc atctccgtgc
     2161 cttcgggggt gaaccacgcc aggtcccgca gcccgtccgg ggcctgcggc gtccccgcga
     2221 agaacgcgcg gcggcgcagc accgggtggg tgtggcgcag ggccagcacc cgggacgtca
     2281 gctccgtcag ctcccgccac tcgggctgct ccagcagcga ccagtccagc cagcccgtct
     2341 cgttgtcctg gcagtaggcg ttgttgttgc cgccctgcgt gcggcccatc tcgtcgcccg
     2401 ccaccagcat cgggaccccg gtcgacagga gcagggtggt cagcaggttg cggagctggc
     2461 ggcggcgcag ggcggtcacg tccgggtcgt cgctctcgcc ctccgcgccg cagttccagg
     2521 cgcggttgtc gtcggtgccg tcgcggttgt cctcgccgtt ggcctcgttg tgcttgtgct
     2581 cgtaactcac caggtcgcgc agggtgaaac cgtcgtgcgc ggtgacgaag ttgaccgagg
     2641 cgtacgggcg acggccgccc caggcgtaca ggtcgctgga gccggtgagc cggtagccga
     2701 gatcgcgcac gtcgggcagg gcgccgcgcc agaagtcgcg tacggcgtcg cggtagcggt
     2761 cgttccactc ggtccacagc ggcgggaagg cgcccacctg gtaaccgccg ttgcccacgt
     2821 cccacggttc cgcgatcagc ttgacgcggc gcagcaccgg gtcctgggcg atcaccgcga
     2881 ggaacgggga gagcatgtcg acgtcgtgca tcgaacgggc cagcgccgcc gccaggtcga
     2941 agcggaagcc gtcgacgccc atctcggtca cccagtagcg cagggagtcc gtgatcagcc
     3001 gcaggacatg gggctggacc acgtgcaggg tgttgccgca gccggtgtag tcggcgtagc
     3061 ggcgggcgtc gtcctggagg cggtagtagc cgcggttgtc gatgccccgc agcgacagca
     3121 tggggccgag ctcgccggcc tccgccgtgt ggttgtagac gacgtcgagg atcacctcga
     3181 tcccggcgtc gtgcagggcg tggaccatct gcttgaactc gccgacctgg ccgccggccg
     3241 tgccgctcgc cgcgtagtcg gcgtgcgggg cgaagtagcc gatggagttg tacccccagt
     3301 agttgcgcag cccgcgccgc agcaggtggt cctcgtgggc gaactggtgg acggggagca
     3361 gctcgacggc cgtcaccccg agccgccgca gatggccgat cgcggcggga tgggcgagcc
     3421 cggcgtaggt accgcgcagc tcgggaggga tgccggggtg gagcctggtg aagccgcgca
     3481 cgtgcagttc gtagatgacc gtgtcggccc agggcgtctt ggggcggcgg tcgtcggccc
     3541 agtcgtcgtc gtcatggacg acgaccccct tggggacgaa cggggccgag tcgcggtcgt
     3601 cgcgcacggt gtccgcgacg tgctgatcgg gccagtcccg gacgtgcccg tagacctcgg
     3661 gcggcagagt gaacgttccg tcgaccgcgc gggcgtacgg gtccaggagc agcttcgccg
     3721 cgttccaccg ggcgccggtc caggggtccc agcggccgtg cacccggtac ccgtagcgct
     3781 gcccggcacc caccccgggg acgaagccgt gccagatctc gtgggtgagc tcggtcagcg
     3841 gcagccgcgt ctcacggccc gccgcgtcga acaggcagag ctcgacggcc tccgccccgg
     3901 ccgcccagag ggcgaaattg gtgccggcca ccccgtccgg gccgacccgg aagcgggccc
     3961 cgagcggcat cggggcaccc ggccatacgg gtggtccgtc cggttcccgc cgcggtgccc
     4021 ctccgcccgc cgccggccgc cccgtcgtac gcggcgcttc ctcctgctcg gctgtgctcg
     4081 acacctctca gcctcccgcg actcgtcgga cgggcccccc ggggaaaggg cgtgcggcgc
     4141 ctgggccacg gcccttcctg gtggtgtcct cccccctgtt ctgcccacgg ccgggcccgc
     4201 actcacgttt ccccggggcg ggcccgtcgt tggggggagc gtgaaccacg aagcgaagag
     4261 agcacgggcg ggttcggccg ccgtgctgac atgggcagga ctgttcaccg tgctggccgt
     4321 actcacgggc tgcacccagg cgacgtcgtt cttcggggac ggccgcgcgc cgggggacgc
     4381 catccgcatc gtcccgaagg acggtgccga gaacgtgggc gcggacgacc ggatcgaggt
     4441 gaccgtcccc gacggccggc tcgaacgggt caaggtgaca cggatcgagg acgcggagca
     4501 ggaggaggtg ccggggaaga tcgccggcaa cggccggtcc tgggcgccgg aagacaagga
     4561 gtaccggctc gggctcgccg ggaagtacag cgtcgaggcc gtcgcggtcg acggcgacgg
     4621 ccgccgctcg gcccgcagca ccaccttcac caccctggtc cccaaggacc gcttcatcgg
     4681 ctacttcaag ccggagaacc ggtcgaccgt gggcaccggc atgatcgtct ccttcgactt
     4741 caaccggccg gtcaggaacc gcgccgcggt cgagaaggcg atccggatca ccaccgagcc
     4801 gcaggtcgag gtggtgggcc actggttcgg cacggagcgg ctggacttcc ggcccgctca
     4861 gtactgggag ccgggcaccg aggtcaccgt cgacgtcgga ctgcgggacg tggagggcgc
     4921 cccgggcgtc tacggcagcc agcgcaagaa ggtgaccttc cgggtcggcc gctcgcagac
     4981 gtccgtggtc gacgccgcgg cccacaccat ggaggtgcgg cgcgacggcg aggtcgtcag
     5041 cacggtgccg atcacggcgg gcgccgagaa gaccacgacg tacaacggga agatggtggt
     5101 ctccgagctg cacgaggtga cccggatgga cgggcggacc gtcggcttcg gcggcgagta
     5161 cgacatcaag gacgtcccgc acgccatccg gctcaccaag tccggcacct tcctgcacgg
     5221 caactactgg gaatcccccg acatcttcgg ctccgacaac accagccacg gctgcatcgg
     5281 actgcgggac atcaagggcg ggagctcgga caccccggcc ggatggttct tcgagcggac
     5341 cctcgtcggc gacgtggtcg aggtggtcaa ctccacggac aagacggtcg ccccggacaa
     5401 cggcctcagt ggctggaatc tcgggtggcc gcagtggaag gcgggttccg cgctgcgctg
     5461 accaccgtcc cgacctgcac aggtcccggg gaagacctcc ccgggaccgc cggccggctt
     5521 ctcggggatg acgggggcgc gttgggacac aacggtgaca ttccggggga gttctcctcg
     5581 cgcccggtgt gattgtcttg cgccgagcgt gcacatctag cgcgcgggag tgcgggccat
     5641 ggcggggcca ggccgtgcga ggggagacga ccacgatgaa cgggctgccg atatcggggg
     5701 catcggccgg ggccggcagg ggacgggacg tgcgcggggc tcatgggcct ctggcactgg
     5761 tactcggcgc cctgctgttg ctggtgacgg cgtgcggggg gagcggcgcc gccgccgaca
     5821 agggtgagga cgccaaggcc gccccgcgga agaccgcgga caccagcgcc tcgcaggcgg
     5881 tggtgaccat cgcgccgaag gacggtgccg acggtgtggc gaccagcggt gaacttcaga
     5941 tcacggccgc gcgggggaag ctgagcaccg tgaaggtcgc cgaccccaag ggcaacgagg
     6001 tcgcgggcgt gatcgccgcc gacggactga gctgggtgcc ggaccggcat ctggccgcgg
     6061 cgaccaagta cgcggtgcac gcggtggccg aggacgagaa gggccgccag tcggccaagg
     6121 acaccacctt caccacgctc gtgccgaaga acaccttcat cgggcagtac acccccgagg
     6181 acggttcgac ggtcggcgtc ggcatgccgg tgtcgatcca cttcacccgg ggcatcaccg
     6241 accccgaggc cgtcgagaag gcgatcaagg tgacggcgga gccggccgtg gagatcgagc
     6301 cccactggtt cggcaacgac cgcctcgact tccgcccgga gaagtactgg gccgcgggca
     6361 ccaaggtcac cctgcgcctc gacctcgacg gcgtcgaggg acggccgggg gtctacggca
     6421 agcaggccaa gaccgtgtcg ttcaccgtcg gccgcagcca ggtctccacc gtcgacgcgc
     6481 gctcgcaccg catgaaggtc gtccgggacg gcaagcagat caaggacatc ccgatctcgg
     6541 cgggcgcgag gccgacgacc acgtacaacg gtcagatggt catcagcgag aagctggagg
     6601 tgacccgcat ggacggtgac accgtcggtt tcggcgacga gtacgacatc aaggacgtcc
     6661 cccacgcgat gcggctgtcc acctcgggca ccttcatcca cggcaactac tggggtccgt
     6721 cgagcatctt cggctcgacc aacaccagcc acggctgcgt cggcctgcgg gacgtgcgcg
     6781 gaggccggga cggaaaggcc ccggccgcct ggttcttcga caactcgctg atcggcgacg
     6841 tggtcgtcgt gaagaactcc gacgacaaga cgatccagcc ggacaacggc ctcaacggct
     6901 ggaacatgga ctgggcggag tggaccgagt aggtaccctc cgcgcggcgg gcccggtgct
     6961 gtgaccaacg gcaccgggcc cgccgccgtt agcggcggtt aacctgcctc tcatgaccgt
     7021 aaccctcgaa gtacgcgaca acgtcggcac gatcaggctg gaccgtccgc cgatgaacgc
     7081 cctggacgtc gccgtccagg accggctgcg ggagctcgcc gacgaggcgg cgcggcgcga
     7141 cgacgtgcgg gccgtgatcc tctacggcgg ggagaaggtg ttcgcggcgg gcgcggacat
     7201 caaggagatg caggcgatgg accacacggc gatggtcaag cgctccaagg gcctccagga
     7261 ctccttcacc gccgtggcgc gcatccccaa gcccgtggtg gcggccgtca ccggttacgc
     7321 gctgggcggc gggtgcgaac tcgcgctctg cgccgacttc cggatcgccg ccgacaccgc
     7381 caagctcgga cagcccgaga tcctgctggg gctgatcccc ggcgccggcg gcacccagcg
     7441 cctcgcccgg ctcatcggtc cgtccaaggc caaggacctc atcttcacgg gccgtcaggt
     7501 caaggcggac gaggccctga cgctcggcct ggtggaccgg gtggtgcccg ccgccgaggt
     7561 gtacgagcgg gcgcacgcct gggccgcgcg gctggccaag gggccggcgc tggcgctgcg
     7621 ggccgccaag gagtccgtgg acgccgggct ggagacggac atcgacaccg ggctcacgat
     7681 cgaacggacc tggttcgcgg gcctgttcgc cacagaggac cgggagcgcg ggatgcgcag
     7741 cttcgtggag gaggggccgg gcaaggccac cttccggtga cggagcgtca accgcccgta
     7801 cgtggggata cgcggtgacg cctgttcatc cgtgcgggcg gatcggcggg accttaaggg
     7861 agccttaagg tcccgtgcct cctccggctc ctgcaattac ccgaaggtcg cgcgtcgccc
     7921 cagttgggag cggttttcga cccttcttcc tgcctctggc atatgccaag cagctggacc
     7981 ggaagggctg tgtgcgggtg ttggattcgc cgggaacggc cacggagcgc ccgcgcggcg
     8041 gccatgatgg ggggcatggc gggcctggag ggtgtggagc agccgcgacc gcgcagcagt
     8101 gcggcagcgg cacgctggag tacggccgcg gatgacgaac aggcgttcaa agaactggag
     8161 ttgttcggaa atccgacgga ggaagaggtg cggttgccct cgcgcccgca gtccgcggcc
     8221 actgcccggc ggatcacctc ctgcgtgatg ctgcgacagt ggcaactctc gccgcagacc
     8281 gccgagcacg gtgtgctgct cgtctccgaa ctcgtcggca acgcggtacg gcacaccggt
     8341 gcgcgggtct tcgggctgcg gatgctgcgc cgccggggct gggtccgtat cgaggtgcgc
     8401 gacccctcgc gcggcctgcc ctgcctcatg cccgtccggg agatggacgt cagtgggcgc
     8461 ggcatcttcc tcgtcgacaa gctctccgac cgctggggtg tcgacctgct gccgcgcggc
     8521 aagaccacct ggttcgagat gcgcaccacc gaccgctgat ccccacgcac accagaagcc
     8581 cccgtcggcc ggggtgcggc gcttcggggg cttctgtggg gggccgtgga atggggggtg
     8641 tgtccacggc cgcttgtggg acctggctcg ggtcggagga ggtcgtgtca ccgactatgg
     8701 cagatgggcg acgccggtgc caaaacccca cttggtgcac tgttgggcaa aacggtctat
     8761 ttcgcttctg aatcacaggt gtgatgggtc acttgcctgg tttttgccgt acctggaggg
     8821 gctgggcgag tgattcattg atcacctcag cgaagtgtcg tgccccgtgt gccaccggtc
     8881 gggccctacc gtgtcccggg tcacgggagc gcccgctccc gcccggaacc aggggggggg
     8941 ccgccatgga cggtcgcagg acggtggtgc tccgccgcac ggccctgcgc gccgccgccg
     9001 gcgccctgct gaccggcgcg gccaccggct gtgcggacgg cggccggggc gcccacgccc
     9061 cgcaggggcc gcgctccgca ccggaggggc cgcgctccgc accggagccg gacggcgccc
     9121 ggcaggcgga cggcgcccgg cagacggagg gcccgggccg gatggccgcg gctccccgcc
     9181 gcttcgcgag cctgcccggc cagatcgagc acggctcccg tgccaggccc cgggtcgccc
     9241 tcaccttcgg cggcgagggt gacccggccc tcgccctcag ggtcctggcc gacgccgagc
     9301 gggcgggcgc ccggctcacc gtcctggccg tcggcgactg gctcgacgcc caccccgaga
     9361 tggcccgccg gatcctcgac ggcggccacg aactcggcaa ccacacccag agccaccccg
     9421 acgtcaacgc gctggacgag gcgcgggcgt acgcggagat caccgactgc gcccgacgtc
     9481 tgcgccgcct caccggctcc atcggcacct ggttccggcc ctcgcgcagc cggcgcgcca
     9541 ccccgctcgt cgaggacctc gcccgccggg ccggctaccc gcacgtcctc tcctacgacg
     9601 tggactccct cgacctcacc tcgccgggag tcgcggcggt cacccgcaag gtcaccggcg
     9661 aactgcgcaa cgggtcggtg gtgagcctgc acttcggcac ccgggacacc gtcgccgcac
     9721 tgcccctcct gctcaccgag atcgatcggc ggggactgcg cgcggtgacg gcgacggagc
     9781 tgttcacctg aggtaccggc ccggcggggc tgcgcgctcc ccgggtgggc gacgccgacg
     9841 cggcggcacg gcaagactgg ccgattctcg agcgtcccgc gcggcgcggc cgtcgatccc
     9901 cgtcccctgc ccgcgttcca cggacgggcc tgtcgcgatc cacagggccc ggggacctgt
     9961 cgccgggtcg ccgggccctg tggccgtccc gcgtgcgccg tcaggcggcg aagtgccgcg
    10021 agagggtgtc cctgcggtcc acctcgacca gatcgggacg tgtgtagcgt tcggcgcgcg
    10081 cgtggtagtc gaagtcgccg cgcaccaggc cccggtagtc ccgtacgcag cactccaggg
    10141 ccgccctggt ggatccttcg atgccggccg ccgctatttc ctcgacgagt tccctctcgg
    10201 cccgctggac tcgctcggcg atgcgtgcca gttgaattcc ggcctcgtcg acggcctcct
    10261 ggagcgtggt cctgcggtcc cgctgaatga gccggaccgc gttgtgctca tatccgagaa
    10321 cggcctcctt ctcgaaggag cagatgtcgt tgcacagacc cgaatgatcg gtgaccgcgg
    10381 tgcgcagggc gatatacgcg ggcaggctgc gggcggattc cggaagatct atcccggcgg
    10441 tgatctcatg gagatccagg aagggctgca tggccacgga gtcccggcgg tgccgggcga
    10501 agtcggcccg gctcggcacc tgtcccgccg ctcgctccac cgcctccgcg tagtaggtcc
    10561 agagccaggc ggcggtgtcg cggcggaact gccggttcca ggcgggcgaa cggtcgcggc
    10621 aggtgcggtc ccgcagtcct tcgagcgcgt gctccatggg gaccagcggc ttctccccgt
    10681 ccagtacgtc caccagccgg gcgatggatt tctcgcacat ccgcgggtcg cggccggccg
    10741 gtccgtcgtc gaactcgtcg tccaccagga acgcccagaa aagccactgg cagaagagat
    10801 cgagatcctc ctgggaggct cgcgggaata tgagcgaaat ccagagttcg gggcgcgtgc
    10861 ggagcatctt cttccgggcg acgggggaga gatcgaggtc gttctcctcc gcccaccgcc
    10921 aggccgccgc cttggtctcc tccatgcccg gattgcatcc cgcgctctgg aacggcatat
    10981 gaaacaccgg taaaacaatc tggctcattg gtgcccctcg tcgaaatgat gcggatggac
    11041 gccgggatcg gagaaccgat cgacgtgacg caccggggac ggacagccgg agtggggcgt
    11101 cgggcgcccg ttggctctgg ccaaagggtc actgtacgag gtgagacggc caacgcggac
    11161 ctccttccgc ccccggggcc ggtcggtccg gccgggtgcg cggaacggtg gaaaccgccc
    11221 gcgtcaccat gcgtcacgac cagtgaaccc cgtgtgggtg gcggagggaa gtcgtatgtg
    11281 accgaaactg catgatcgca gcgaacaact ggtcatcact gagcatcttg tgactcggtg
    11341 gcgggggtgt ccggcaccgg gccggcgccg gcccgggggg ctcggcggga tgccggagcc
    11401 ccccggacgg gctcagccgg acccgtcccc gtacgcctcc tcgaaggacg cccggaacag
    11461 ttcctggacc tccgcgccgc ccagtccctc ggcccgcgcc tggtgcatcc actcgttcag
    11521 cgccgaacgc agcggccagt cggggcccga accgggctgc gccagcgagc gggtgatgaa
    11581 tgtgcccgcc ccctggcgga cctcggccag ccccgcccgc tccaactcgc gataggcctt
    11641 gagcgtggtg ttcgggttga ccttggtggt ggcggcgacc tgggccgccg tgggaagccg
    11701 gtccccctcc tccaacgcgc ccatgcgcag ggcctgctcg acctgacgga cgatctggag
    11761 gtacgtcgcc actccactgc gccggtcgat gcggaacacg accaccggca tcaccttccg
    11821 ctccgatatc gactcatgtg taggagaact tgtttgcggg agaactcatg tgcgggagaa
    11881 aggggcaggc cctcagagcg ggcgccgggc cgaccgcagg acgacgaacg cggtgagcgc
    11941 cgccgtgccg gccaggagga tgcccgcccc ggtccactgc atggccgcca tctggtcctg
    12001 gccgaggtac tcgatgacgt tgtcgacgat gcccttctgt gcgaggcacg cctcctgtgc
    12061 cttctccgtg gcctcgacgc acgatcccca tccgtacagc tttccgtcgg cggtgccgac
    12121 ccaccgctcc acctcgtacg actcggagag gcgggcgggc agttcgctgt ccagcgggta
    12181 ggtgaccatg cgtgtcgggg cgagattctg ccggatcatg ctccaggccg tctccaccgc
    12241 cacggcgaag acaaacgtga cgaccatcga ggcgagcacc cggcgcagca ggacaccgat
    12301 ggtcaccccg gcggcggtga ggaacagcgc gagggccggc aggacggggc cggtgttgtc
    12361 gaacacctcg gcgtccagcc acgagatcga gagcaccgaa cggtacggcc gccaccacca
    12421 ggtgaagagc gcggagagca ccgcgcacgc caacagggtg gcgccgaagc accagccgag
    12481 cttcgcgacc agccagcggc ggcgcgtcac ggactgggtg gtgacgagct gggcggtgcc
    12541 ctgctcggtg tcggcggcga ccagtggggc gccgaggaag acggcgagga cgacagggag
    12601 cgcgcccagc agcatcgtca gcaagctgta ctgccggccg gtgaccggct gccctgcgcc
    12661 ctcctccggc cggcccgccg cgtcgagcag atcgatcagc tgggcgcgct ggtacacgat
    12721 ccagagcgag acgagcagcg tcaggcccag caggcagagc aacgccgccc ggtgctggcg
    12781 caggaccagc cagttcaggc cgcgcaccat ccgccgcggc gtggcgcgtc cggtggacgc
    12841 gtcggtcgaa gtggtgctca tacggtcctg gcctcctggg gatcgacggc ggcgccgggc
    12901 gtgtacagcg cgggcgcgtc cggtgaacgg agatgggcga gcagcacttc ctccaggctg
    12961 ggttccgaga cccgccagtc accggtgagc gggccctggg gccgcaccat cgcctggaac
    13021 tgccggccgt gcacccggct ctcgatcacc gtgtggcggg tgagcgcggc gggcagcgac
    13081 ccgtcctgag tcaccccggt caccagcgcg tgggcgggga ccagggcgtc ggcgtcaccg
    13141 gccatccgca ccctgccctc ggcgaggacc aacaggtagt cgcacatgtc ctccagctcg
    13201 gtgagcatgt gcgaggacat catcacggtg gtgccgcgct cgacggcctc cgccatcagc
    13261 agggtgctca tctcgtggcg ggccagcggg tcgaggtcgg acatcggctc gtcgagcagc
    13321 aggagatcgg gccgcttgcc gaacgcgagc gcgaaggcga cccgggtccg ctggccgccg
    13381 gacagggtgc cgaccgccgc gtgcggcggc acgttgcccg cgcggacgat ccgttccgcc
    13441 gccgccatgt cccagtccgg gttgagctca gcgcccatcc ggagcgtctc ggcgacggtg
    13501 aaccgtttga acagaggctt gtcctggccg aggaacgcga acctcggcat cacctcccga
    13561 tcgctcaccg gcaccccgaa gaggcgcagt tcgccctccg tgggctccac ctgccgggtg
    13621 gccatgccca gcagggtgct cttcccggca ccgttgggcc ccaccaggcc gcagatccgt
    13681 ccggccggca gccggaagga acagtcccgc agtgcccagc cgcggcgata gcgcctgccc
    13741 aggccgcggg cctccagggc ccacgtgccc ccgggcccgg tcgacgtgct cttccctgtc
    13801 acgcttcccc caattccatg aatcaattaa tggaatgatg gttatgaggg gcgggcatgt
    13861 caaaccgcgc cgtggcggcg ggtgtcgggt gctcgcacga tgcgctcggg gggagccgta
    13921 gggcgcgccc ggagtcgtcg gcccggggcg gggcctcgcg gcgagaggga gggggagcgg
    13981 cgcgggtgcg gggcgccggc cccgggtgcg ctcaccgggg catggctgtg gcccccggcc
    14041 gtggccgggg gccgcgagag gcggtgcggt cgtcgggcgg gcgccgcccc ggccccgcga
    14101 cgcaccgcgc gggggcccgg ggcggactcc gtcccggtca ggcgtccggc gtgtcctcgg
    14161 tcgccgtggc cgtccggccg aggtgggcga cggcctcgtc cacatgggcg tgcacgggca
    14221 tcagatcacc gacgcctgtc atgtccagga gtctggtgag ttgatcgggc gcggccgcca
    14281 cggacaagga cccgccgcgc tcgtgcgcgt gctgcactat ggcgatcagg gcgttgagcc
    14341 cggacgagtc gcagaactcc acgggtgcca tgtcgagtac gacgtgcggg catccctgcc
    14401 cgatcagttc cgtggccttg gtgcgcagtt ccggtgccgt atccacgtcg agctcgccgg
    14461 agacggtgac gaccgcgagc gagtcggccg ggtgccggac ggtgagaaga aggttggtgc
    14521 cgtgagtcat ggcgtcagtg ctcctgggcg gggcggacga ctgcggcctg acctgtggga
    14581 gcgagccggt gcggtacggc cacaggcatc acccgcaggt gccgcgctgc ccccaggcgt
    14641 accttccggc cgatccgatg ggtggccgcc agaagatcgc tcatcgaatc tggactgcgg
    14701 aagcgtaccc cacggcaact gtttccccga gggacgctcc ccggggccgg acacggtctc
    14761 cgagacctgg ggtcggcggg ggtaagatac tcgtggcaca cgcgtgccct tgaggcgagg
    14821 ctgtggcctg actttccgta cgagcgcaat cggatgcccg gcacgcttgc tcggtccggt
    14881 ggccggacgg agccagacag acgagtgaga ccatgccgga tcggagtgtc atctaaatgg
    14941 gcctgaaccc cgaaccagac caccggtccc gggacgcggc ccacgagggt tccgaggtca
    15001 tcgagctgct cgaagtcctg tgggagcgtg ggcgcgaggc agtgcccacc ggcccggtgt
    15061 ccccgtccca gctccgagtg ctgtacacgc tcgaccgtga cgagggcatc aatctgcgga
    15121 tgctcgccga ggccctggga tcggcctccc cctcggtcag cagactgtgc gaccggctgc
    15181 aggccacggg attcgtggag cgggccccga gcccggtcag ccgccgcgaa ctggaactgc
    15241 ggctgaccag tcacggcaag gcatacctcg tcgacctgcg gatgcgccgg gaacaggtgc
    15301 tgatgtcgac gatcgacgcc atgccgccca aggcccggcg cgcgctgctc gaagggctca
    15361 gaggtttccg cagcgcggcc gcggcggccg gccaggacga cggcgcggcg agacccctga
    15421 ggtcgaccgg atagcggatc ggcctctcac gcctgcgtgt caccgttcgg ggcctgccgc
    15481 ccgtaccagt cgagacagac caccagggcg tcgtcgtcca gtggggtcgc accgccccgg
    15541 tactccttca gatcacgcag aaccgccagc gggacctgcg ccgacggcag gaagcggtgc
    15601 gcggacagcg accgtgccag cgcgcgttcc ccgtagcgct ccccggcggc cgaggcgctc
    15661 tcgtagaccc cgtcgctgct caccagcagc cggtcaccgg gctccacacg caggtgctcc
    15721 gagacgtaga ccgtctcctc gaacatcccg agcggcagct gcgcgtcgaa ggcgacggac
    15781 tccacaccgc gtccccgcag ccgccacatg cgcggcgacc ccgcgtccac ggcctcgacc
    15841 tcgccggtgg ccaggtcgaa ccgcagcagc aggaccgagg cgtgcagcgc accccggtac
    15901 tgcgcgtaca ccgcctggtc ggcgaggctg gcctggccgg gcaggtccag cccggcgcgg
    15961 cgcgcgttgc gcagcgcgtt gacgacgagg ttggtgagca gcgccgcctc catccccttg
    16021 cccatgccgt tggtgacggt gagtgtgagg tgatgggcgg agaccgacca gtcgaagttg
    16081 tcgccgaaga tcgcgtacgc aggctccagg tgtgcaccca gcgagaactc gggccgggtg
    16141 accgaccgcc ccggcagcag ctgccactgc atctcggcgg ccagtgtcag gcgcgtcgca
    16201 cggcgggcga ggaggtagag gtcggtgtcc cgttcggcga cgaggatctc gtggccgagc
    16261 gcctcgcaga ccccctgcat ctcccgcagg tcagcccggg tgcggtcgtc cgaggtggtg
    16321 acggtgagca cacccatccg gtcccccctg accgtcaccg gaaggtgcac cgtcacgggg
    16381 ccgtcgccca cccggggctc gacatagggc tcctgggcac cgaaggcccg cccttgcggg
    16441 ctgtcgtgga tgggtaccgg ctccacgagc ggcacctccg cgaccacctg cagggtggtc
    16501 accccgtagt cggcgagccg cagctccacg ctctgcacgt cgtactgctc ccgcagagcc
    16561 gccgtgacga catcgaggag caagtcgggt gcggcattgc gcaacgcccg ctcgacggca
    16621 gcgattctgt ccacgtgatc ctgtttctcg ttcgagccgc gccgaacccg ggccgaccgc
    16681 gggcccccga gccgtcggcg ttaagcgtac ggggcctgta cccaatcaag cgcggcgcgc
    16741 ccgaaaggtc gctccggtgg ctggggccgt caggtgtggt gagtgactgg cgagggccgg
    16801 ccacctgggt ctcatcttac gatgtacaga gacaacagtt tccacacagc aagaaaaatt
    16861 cggttcggcg cgcatgtgcc ccgagaagcg gggcaggggc cctctcagga agtacgcatc
    16921 accagggagg gtaggcacat gtcattgatc tccgaacggg ccgctgagac cacggcgagt
    16981 gacgaggtgt cggctccgga cggcggggcg gcatccgtcg gtgagctgcc ctggatcgag
    17041 gacgccggga agatcgcccc caaggacgcc cgcgagctgt ccacactgtt cttcgcccag
    17101 ctccaggttc tggaggaggg cacgcacgag taccagtacg cgcggaacac cctcatcgag
    17161 atgaacatct ccctggtgcg gttcgccgcg cgccgcttcc gcaaccgggg cagcggcgac
    17221 atggaggaca tcacccaggt cggcatcgtc ggcctgatca aggcgatcga ccggttcgag
    17281 ctctcccgtg aggtcgagtt cgccaccttc gccgtcccct acatcgtcgg ggagatcaaa
    17341 cgattcttcc gtgacaccac ctgggccgtc cacgtgcccc gccgcctcca ggaactccgc
    17401 gtggagctcg cgaaggccaa ggaggagctc gccgtacgcc tggaccgcga ccccacggtg
    17461 aaggaactgg ccgagtacct gggcctcacc gaggacgagg tggtcgaggg catcgtggcc
    17521 tccaacgggt acacggcggg ctcgctcgac ctgccgaccg acgccaacga ggcgacggcc
    17581 acggcgaccc gtacgttcgc cgacatcctg ggtgagccgg acgccgccat ggagaccgtg
    17641 gagaacctgc acgcgctggc cccgctcctg gaggagctcg acgaccgcga acggcgcatc
    17701 atcgagatgc gcttcggcca ggagatgacc caggcgcaga tcggcgccga gctcggcatc
    17761 tcccagatgc acgtctcccg tctcctcagc cgcaccctcg gcaagctacg caccggcatg
    17821 ttcgcctgag cggccgggcc cctcgccagc ccgtcccacg acgacgtccg ccctcccttc
    17881 ccagcggccc gcacccgtcc ggtgcccgcc gcgccccgac gcccctgagg agaagaaccg
    17941 ccgtgctgat ggcccacccc gtgatcctgc gcggtctcgt cgaccgctac cacgagctgc
    18001 tcgcccagga ctccgcgcag gggtcccagg agacccggtg ccaactggag gacgtcacct
    18061 acacgttgtg cgtctccacc ggcacccgca ccgcggacga ggccctggcc gtcgccgagc
    18121 agcagctcac cgcggccctc cgcgacccgg cactccgcgt cgggcggccc ttggacgcgc
    18181 agctcacggc ctcctgaccg aggagcgccc ggtacggggg cggggcgtcc gcccggtaag
    18241 cactgttccc gcgccgatca gcgggacacg gaaccggcgt tccgccacac cgagacgtgc
    18301 gatccgctgg acgcggtgaa gggcgtcttg gacctgtcgg cccaacgctc cggcaggtcc
    18361 gggccggcct tgacggaccc ggccacgtcg ccgccgccgg gcttcttgcc gagtccctcg
    18421 gccatgggcg ccgacttctc ggtcccggac acccgtacgc ctcggcgtgc ttcactcagc
    18481 cgcccgggca ggggcccggc cccggcatcc gctcaggccg cggggcccag gtgttcccgc
    18541 gcccactgtt cgaagcccgt cacctcgatg cccagcgcgc gagcgaactc cggccgggcc
    18601 ggctggccga ccgcgtccat gaaggcgtgc gtggcaccca tgtcgcccat cccggcggcg
    18661 cgggcctgtt cttccgtcat gtccggtgcc gtcagcggga cccccagggc gcgggagagg
    18721 atctcggcga tcgcggtcat ggtgaggtgg tcgccggcga gctccagttc cacccggtgg
    18781 aactcgacgg gcgcggacag ggcggccgcc gcggcccggc cgacgtcctg ggccgccacg
    18841 agtgccaggt gtgtgcccgg tttgacgacg gtgaccaggc cgccttcgac gccgcggggg
    18901 aagtagaacc gcatggacgg ctcgaagttc tccatgaaga acgacggctt gatcaacgtc
    18961 cagtaaggga agtcgagttc gcgcagccgg tcctggatcg cggccttcgt gccgagcggg
    19021 gcctccatga tcgcccaccg cccttcggcc cagcccggag cctcgacgtg ccggcccacg
    19081 ccgctggtcg aggactggac gaactgctcc acaccggcgg cccgcgcggc cgtcatgagg
    19141 ttgtccgcct gggcgacctc gcccgcgaag tcgaacccct gtccggtgta cgcgggcatc
    19201 tgcacggaga agacggcccg cacaccgtcc acggccgcag tgagggtcgc cggttccgtg
    19261 agatcaccca cgaacaggtg tgcgcccagc gcttcgacgg cccgcgcgcg cggcgcgtcc
    19321 gggtcgcgca ccagggcgcg caccggtgtc ccctgggcga gcagggcgcg ggcggtggcg
    19381 ccgccttgac ggccggtggc gccggtgacg aggaccggcg gtgcggcagt ggtcatgggt
    19441 gcatctcctc gggatcacgc ggacggaaac ggcggggccc gccgtttcgc gttcgctaca
    19501 atacggcggg gcccgccact tatcaacgtc gaggagatca tgaccggcca gcgctcggac
    19561 gcccgccgca attacgcgca catcctcgcc gtggccgagg ccgaggtggc gacccagggc
    19621 gcccaggcgt ccgtggagcg catcgcccgc gtcgcaggcg tcggatcagc caccgtgcgg
    19681 cgccatttcc ccacccgcaa agccctgctc gaagcggtct tcaagcagcg tgtcctggtc
    19741 ctgtgcgagc gcgctcagac actccgcgac gacgagaacg acagccgcgc cgcgctggtg
    19801 gaatggctac gggagctgct cgcctactcg ctcgccgcac ggggactggc agacgtcctg
    19861 tcctacgagc ccctccagga cgaggccacc caggactcct gcgcgggagt catcggggcg
    19921 gccggcgcct ccctgctgcg cagagccgtc gacgaccagg ccgtccgggc ggacgtcacc
    19981 atcgacgacc tgctcacgct gatcgtcgga atcgccctgg ccaccgagaa ctacaccgac
    20041 ccggcggcgc acgcggagcg cgccttccgg ctcgccgtcg cgggtctgga cgccacccgc
    20101 acctgagcac ccgggcccga ccctcacggg cccgggcccg gggtggccgg cacctacgag
    20161 cccgactccg acgacgtcga gcggccggac accggatcct cacccgcttc gggcccgaac
    20221 ggcacgacga cgatctgtac gtcgtcctcg tagacgatcc gccccggagc cgtggagacc
    20281 accttccggc aggcgacgcc gtgcgcggcc agaaggccca ggtagccggg cacccgctcg
    20341 atcaggtgcg tggccgtcgg tttgaaccag gccgcggcgc ccgggttgac ggtgtcgtcg
    20401 tagacggccg gatcgacggt cgaggggtcc gggtacgccg cgtcgtacca gcggttgttc
    20461 gcccggcgga acgcctcctg cccggccgtg agccgccccg tccgcgccag cgtgttgacc
    20521 agcccgaaca ccccggtgaa cgtgctccgt tcattgcggt gcggtgactg gaaccgcaca
    20581 taccggaccg tgtgaccgtt cgtccccatc cggtcatcct gtcaccgggt gcggccgcct
    20641 cgcagaggcc cgcgtcacgg cggcggggcg cggcagcgct cagcactcga tgatgttcac
    20701 cgcgagcccg ccgcgcgccg tctccttgta cttcacggac atgtccgcgc cggtctcctt
    20761 catcgtcttg atgaccttgt cgagggagac cttgtggctg ccgtcgccgc gtagcgccat
    20821 cttggccgcc gtgaccgcct tcaccgccgc catgccgttg cgctcgatgc acgggatctg
    20881 caccaggccg ccgaccgggt cgcaggtcag gcccagattg tgctccatgc cgatctcggc
    20941 ggcgttctcc acctgctcgg gggagccgcc cagcacct
//
