LOCUS       NC_015953              21044 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. SirexAA-E, complete sequence.
ACCESSION   NC_015953
VERSION     NC_015953.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Streptomyces sp. SirexAA-E
  ORGANISM  Streptomyces sp. SirexAA-E
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7414440)
  AUTHORS   Takasuka,T.E., Acheson,J.F., Bianchetti,C.M., Prom,B.M.,
            Bergeman,L.F., Book,A.J., Currie,C.R. and Fox,B.G.
  TITLE     Biochemical properties and atomic resolution structure of a
            proteolytically processed beta-mannanase from cellulolytic
            Streptomyces sp. SirexAA-E
  JOURNAL   PLoS One 9 (4), e94166 (2014)
   PUBMED   24710170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Streptomyces sp. SirexAA-E
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2011) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. SirexAA-E
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            environment                       :: Soil, Terrestrial
            num_replicons                     :: 1
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly                          :: Newbler v. 2.3 (pre-release)
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi05895
            Funding Program                   :: DOE-GLBRC 2008
            Source of Isolate :: Cameron Currie (currie@bact.wisc.edu)
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method                   :: Newbler v. 2.3
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000177195.2-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 02:12:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,619
            CDSs (total)                      :: 6,532
            Genes (coding)                    :: 6,385
            CDSs (with protein)               :: 6,385
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 61 of 147
            Pseudo Genes (incomplete)         :: 120 of 147
            Pseudo Genes (internal stop)      :: 8 of 147
            Pseudo Genes (multiple problems)  :: 39 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4947660
            Orig. end                         :: 4968704
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002993.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086644
            Source DNA and organism available from Cameron Currie
            (currie@bact.wisc.edu)
            Contacts: Cameron Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21044
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="14"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21044
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21044
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11044](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(958..1215)
                     /locus_tag="SACTE_RS22220"
                     /old_locus_tag="SACTE_4474"
     CDS             complement(958..1215)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="SACTE_RS22220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4474"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_003953983.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARNASA"
     misc_feature    1258..1273
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(1259..1270)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    1436..1445
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    1495..1508
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            complement(1535..2503)
                     /locus_tag="SACTE_RS22225"
                     /old_locus_tag="SACTE_4475"
     CDS             complement(1535..2503)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="SACTE_RS22225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4475"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_014048262.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRRAADSDDIDIVVALGGDGTVNEVVNGLLHKGPDLENLPSLAVVPGGSTNVFARALG
                     IPNDAVEATGAILDALADRSERTVGLGLAAGTPGSPDEAVPERWFTFCAGLGFDAGVIG
                     RVEQKRERGKRSTHALYVRQVLRQFLEEPHRRDGLITLDAPGQDPVTDLALSIICNTAP
                     WTYLGNRPMYAAPRASFDTGLDILGLRRLSTAAVTRYATQLLTSSPEKGPHGKHAVSLH
                     DLTDFTLHSKAPLPFQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    2566..2579
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: strong, score: 22.69"
                     /tool="antismash"
     misc_feature    complement(2567..2580)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.15"
                     /tool="antismash"
     gene            2652..3101
                     /locus_tag="SACTE_RS22230"
                     /old_locus_tag="SACTE_4476"
     CDS             2652..3101
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072100.1"
                     /locus_tag="SACTE_RS22230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4476"
                     /product="hypothetical protein"
                     /protein_id="WP_026358936.1"
                     /transl_table=11
                     /translation="MSTEANAPSPSPSAGEEKPGRITLVAALNALEGAALALGGVYMLV
                     MGLLGRPDSPQQAEMGGLTLVALGLIPLFAARGLLLRRSWSRGPALITQLMALPVAWTL
                     LRSQGALIPAGIVLAVVAVTGLVLLVDPATTRALGIRGPRATPDA"
     gene            complement(3126..4070)
                     /locus_tag="SACTE_RS22235"
                     /old_locus_tag="SACTE_4477"
     CDS             complement(3126..4070)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072101.1"
                     /locus_tag="SACTE_RS22235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4477"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_019992370.1"
                     /transl_table=11
                     /translation="MRDETIRSEVVRPAAVPEQQARPHPVDGADAAGGVDGARGRTVAV
                     EQSQAERAGQMSEHGHHDPHDRSGARALFVELRELPDGSAEKAELRNRLVRMHLPLVEH
                     LARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDKGW
                     AVRVPRRLQELRLSLTTATAELSQQYGRSPTVHELAERLGISEEEVLEGLESANAYSTL
                     SLDVPDTDDESPAVADTLGSEDEALEGVEYRESLKPLLEGLPPREKRILLLRFFGNMTQ
                     SQIAQEVGISQMHVSRLLARTLAQLRERLLVEE"
     misc_feature    complement(4046..4060)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            complement(4094..4507)
                     /locus_tag="SACTE_RS22240"
                     /old_locus_tag="SACTE_4478"
     CDS             complement(4094..4507)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="SACTE_RS22240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4478"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_014048265.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLIDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSTVADDRTVSISLYKQRGAGPGPA"
     gene            complement(4738..4998)
                     /locus_tag="SACTE_RS22245"
                     /old_locus_tag="SACTE_4479"
     CDS             complement(4738..4998)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="SACTE_RS22245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4479"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_014048266.1"
                     /transl_table=11
                     /translation="MSECRHVSELPRPEPSPLSDTCRECLEAGTHPVQLRLCLVCGHVG
                     CCDSSPLKHATKHFRATGHPVMRSFEEGENWRWCFEDGSIV"
     gene            5034..6638
                     /locus_tag="SACTE_RS22250"
                     /old_locus_tag="SACTE_4480"
     CDS             5034..6638
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048267.1"
                     /locus_tag="SACTE_RS22250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4480"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_014048267.1"
                     /transl_table=11
                     /translation="MDALPLVALVAASAAVAGAARRTPVPAPLLLVAVGLLVSYLPGVP
                     HFTLDAHIVLPLLLPPLLYTAAVDSSYLDLRANVRPVALLSVGYVLFATFAVGALAYWI
                     VPDLPLTAALVLGAVIAPPDAVTAAAIARRVGLPARVTTILQGESLVNDATAITAFKVA
                     LAAAVGEGMSWGAGIVEFLLAAVGGVGVGLVLMVPLHWLRTHLGEALLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRSWQVDFATRLQEAAVWKMVAFVLESAVFALIGL
                     QLQSVVRGLGTYGLTDAVRYALAVFVAVVLVRFVWVYPAMYLPLWLSRRIREREPAMPW
                     TSPLIVAWAGMRGVVSLAVAASVPLVTHDGEHFPDRNLLLFLTFTTVIGTLAVQGLTLP
                     LLVRVLKLPGRDARAETLAEAQAQSEASTAAEARLDELLSDPHNSLPGPLSDRLRHVLE
                     RRRNSVWERLGAADPVTGESADDTYRRLARETIDAEREVFVRLRDERRIDDEMLRVLLR
                     RLDLEEAAAYREPDGST"
     gene            complement(6611..7546)
                     /locus_tag="SACTE_RS22255"
                     /old_locus_tag="SACTE_4481"
     CDS             complement(6611..7546)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048268.1"
                     /locus_tag="SACTE_RS22255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4481"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_014048268.1"
                     /sec_met_domain="PALP (E-value: 3.1e-15, bitscore: 54.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDEALDLSRLRPALPSPLEPVEDERFTRHSVTLLLKRDDLIHPD
                     LPGNKWRKLGPNLRAAAGRTVLTFGGAYSNHLRATAAAGRLLGFPTVGVVRGDELAHRP
                     LNPSLARCAADGMRLHFVDRSTYRAKTSPEVLDGLLSLFGECVVVPEGGSNALAVRGCT
                     ELGRELRGPAGTVAVACGTGGTLAGLAAGLGPEQHALGIPVLRGGFLGETVRALQEEAF
                     GGPAGRWSLDERFHFGGYARTTAGLHAFADDFEDRHGLPVERLYVAKLLYALTVLAGEG
                     AFAPGSTVTAVVTGRPDAPQGPQVEPSGSR"
     gene            complement(7580..8170)
                     /locus_tag="SACTE_RS22260"
                     /old_locus_tag="SACTE_4482"
     CDS             complement(7580..8170)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154135.1"
                     /locus_tag="SACTE_RS22260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4482"
                     /product="peptidoglycan recognition family protein"
                     /protein_id="WP_014048269.1"
                     /transl_table=11
                     /translation="MSSPMSANKFLKALEDEGLTVVQVGDWRTHNRNDKGSWGPVHGVM
                     LHHTATEGSARTVDVCREGRTGLPGPLCHGVITKDGRVHLVGYGRVNHAGLGDDDVLRA
                     VVAEKRLPDVDDSGADGNRHFYGFECENLGDGKDPWPAAQLEAVGKAAAALCRFHRWGA
                     SSVIGHLEWQPGKVDPRGFSMNGMRARVREHLK"
     misc_feature    8425..8439
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.32"
                     /tool="antismash"
     gene            8472..9875
                     /locus_tag="SACTE_RS22265"
                     /old_locus_tag="SACTE_4483"
     CDS             8472..9875
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061505.1"
                     /locus_tag="SACTE_RS22265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4483"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_014048270.1"
                     /transl_table=11
                     /translation="MSVGEEVRDTQPPQQSLGTAAARNLATTTKSAPQMQEITSRWLLR
                     MLPWVQVQGGTYRVNRRLSYSVGDGRVTFVQTGDQVAVIPAELGELPALRNFGDEEVLA
                     ELARRCEQREVAPGELLTMSGEAADRVYLLAHGKVEKIGSGLYGDETVLGVLADGAYFG
                     DHTLVDGDATWSYTARAVTACTLLTLSRADVLNLAARADSLRDHLAGLLAIPHQRTNHY
                     GEAEIDLSAGHVGESVVPHTFVDYEAAPREYELSVAQTVLKVHSRVADLYNQPMNQTEQ
                     QLRLTVEALRERQEHELINNREFGLLNNCDYGQRIQPHDGVPSPDDMDELLSRRRGSKL
                     FLAHPRAIAAFGRECNKRGLVPESVEVGGHHVPAWRGVPIFPSNKIPVTDARTTSIICM
                     RTGEQEQGVIGLQQSGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAILVPDALGVL
                     ENVEVSRWR"
     misc_feature    9990..10010
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.96"
                     /tool="antismash"
     gene            10001..11044
                     /locus_tag="SACTE_RS22270"
                     /old_locus_tag="SACTE_4484"
     CDS             10001..11044
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105591.1"
                     /locus_tag="SACTE_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4484"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_019992369.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-61, bitscore:
                     205.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAATEGQEAAVLLERTRGLVDPHLRAAVDTLPGAIRRVARY
                     HFGWQNADGTPASGQAGKAIRPALVLAAARALGGDPESALRAAVAVELVHNFTLLHDDV
                     IDEDATRRHRPTAWAVFGVPDAVVTGDAVLALAQRLLAEDPHPGSARASARLSACVIEL
                     CAGQQADCALEEREPLDVTLDECLTMATAKTGALLGCACALGALYAGADEPAVEAMDGF
                     GREAGLAFQLIDDLIGIWGDTARTGKPVGADLAAHKKSLPVVAALTSGTPAADELAVLY
                     RGAMNTPAEVSGAAAAVDRAGGRDWAQACAADRMARAVHHLSRAVPDPAAAQDLLALAE
                     FVTRRTH"
     gene            11138..11737
                     /locus_tag="SACTE_RS22275"
                     /old_locus_tag="SACTE_4485"
     CDS             11138..11737
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048272.1"
                     /locus_tag="SACTE_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4485"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_014048272.1"
                     /transl_table=11
                     /translation="MGVRVRQADGRDRDQVVEIMEAAFHHDPVSGWVFPDEEHRRAVHG
                     KFLGVFADVALSEGRVDLLEDGTAVALWVSVPAGAPEAEDDTPALMRRTADPDNERAEL
                     VGRLTGAVHPHDRAHAYLLMVGVRPEHQGEGIGEALIGGALEQCDREGVPAYLEASSER
                     SRGLYERLGFTFTGRTVELPDGPSMWPMWREPQAGR"
     gene            11811..12539
                     /locus_tag="SACTE_RS22280"
                     /old_locus_tag="SACTE_4486"
     CDS             11811..12539
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="SACTE_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4486"
                     /product="DUF6304 family protein"
                     /protein_id="WP_014048273.1"
                     /transl_table=11
                     /translation="MTDESWAGWYRDRRGSEAFILTTDGRRLRVRVRGTDFEGESFDAL
                     LPAAGVVPEAGAFDLADGVLGDCVLEWDLPLPVLAAGTVRQATLSCLLSLRRADPDLYL
                     ALHLDGAVYESHRAENDFAAALATIRAVLPPDIQLQICTACALSGYLPASGRGISGGLG
                     CFRDAKDAYRDVTEGSAVAGLWDRRTGLVQEIWSCREFEPRPFEPGLVTGAPAERRTGA
                     PGPTEGAGAGRLGVHPLEHA"
     misc_feature    11860..11874
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.52"
                     /tool="antismash"
     gene            12667..13638
                     /locus_tag="SACTE_RS22285"
                     /old_locus_tag="SACTE_4487"
     CDS             12667..13638
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048274.1"
                     /locus_tag="SACTE_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4487"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_014048274.1"
                     /transl_table=11
                     /translation="MNPKKLGRAVLVALPFLVVLILALVLAGTLSDRLPGRLATHFSAT
                     GEANGYTGRTTFLVLTALVPALLGACWTYMAVRGRFHGRAYDGFTAAGYATAAFFGYLT
                     TVTLFANVDTADGAPGATFTMWHLVGAFGSAAVAAALGYFLARLLPALPDDPEAAAARE
                     GARIPLADGEVAGWVRSMASWWLPGTALAMVLAGVVLTFALRPVTGLPLMVIGLVLLPY
                     SRPNVTVDRRGLIVSGLLPWPRVHVPLERIDTATSRNVKAVAEYGGWGYRVRATRSGVI
                     TRSGEAIVARLENGRDFAVTVDDSATGAALLNTLVDRRRGRS"
     gene            13641..13997
                     /locus_tag="SACTE_RS22290"
                     /old_locus_tag="SACTE_4488"
     CDS             13641..13997
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458277.1"
                     /locus_tag="SACTE_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4488"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_014048275.1"
                     /transl_table=11
                     /translation="MLFRVDPSSSVPLGDQIAACVRRAVSDGSVAPGERLPAARALADS
                     LGVNVHTALRGYQRLREEGLIELRRGRGAVVTAGASPHRARLLEGVRAVVAEARELGLA
                     EGDLLDLVRAELNA"
     gene            complement(14060..14725)
                     /gene="snpA"
                     /locus_tag="SACTE_RS22295"
                     /old_locus_tag="SACTE_4489"
     CDS             complement(14060..14725)
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127499.1"
                     /locus_tag="SACTE_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4489"
                     /product="snapalysin"
                     /protein_id="WP_014048276.1"
                     /transl_table=11
                     /translation="MRHPRTVLMSAVAGLGLAVALGASPAAATAPAHSAPSTSTTNGYA
                     AYAGSSENAAANQAFFEAVMKSVAEKRAAVPGAQAVTVVYSAAQAPSFRSQIASSASIW
                     NSSVGNVKLQEGSNADFVYYEGNDARGSYASTDGHGRGYVFLDYAQNQQYDSTRVTTHE
                     TGHVLGLPDHYSGPCSELMSGGGPGPSCTNAYPDATERSRVNSLWQNGIAAALARAGS"
     misc_feature    complement(14953..14966)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            14976..15929
                     /locus_tag="SACTE_RS22300"
                     /old_locus_tag="SACTE_4490"
     CDS             14976..15929
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959105.1"
                     /locus_tag="SACTE_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4490"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_019992367.1"
                     /transl_table=11
                     /translation="MEFEVRHLRALCAIADTGSLHQAARRLGVSQPALTTQLQRIEKSL
                     GASLFSRERTGCRPTLLGRSVLSRARPLVDGMAALVDAALAEAEAAREGGPRLRIGSTA
                     SRVIGGWLRRLRIRLPGTDISLRVDVSARELLRAVAAGRLDVAFVHEVEGFPLTVPEGL
                     GQRVLLEREPQFISLSRDHPAAARPVVDLDDLAGDRWMVDPSVDGEWDGVRRVLGAAGL
                     DPPVLHGDYLTAASLVVLGEAVAPCQPTSGPREDMAIRPLRGDPLAVRLLLVSRPGTDT
                     DTVYAELEAAYREAARRAAAYHQWLLRHRSPLVAVD"
     gene            16003..17007
                     /locus_tag="SACTE_RS22305"
                     /old_locus_tag="SACTE_4491"
     CDS             16003..17007
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048278.1"
                     /locus_tag="SACTE_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4491"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_014048278.1"
                     /transl_table=11
                     /translation="MRILMLGGTEFVGRAATETALARGWQVTVFHRGHHAPPPGVRALT
                     GDRTRGPAGLTALESGTWDLVVDTWSGAPRAVRDATRLLSGRAGHFAYVSSRSVYASPS
                     PPGRAEDAPPVEGASPDAGGDVSYALAKRGGELAAVDAFGDRALLVRAGLILGPGENVG
                     RLPWWLGRTARGGPVIAPGPPGAGIRYVDARDLASWMLDAAARGLGGAYDVVGGPGHAT
                     MGELLDACVRVTGSGAELRWTDPEVLLAAGVEPWTDLPVWLPAGELYDAVHQADVTKAY
                     AAGLRCRPVGETVADTWSWLCARGGTAPQRPDRPGVGLDARTEARLLAGEGAP"
     gene            17017..17373
                     /locus_tag="SACTE_RS22310"
                     /old_locus_tag="SACTE_4492"
     CDS             17017..17373
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048279.1"
                     /locus_tag="SACTE_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4492"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_014048279.1"
                     /transl_table=11
                     /translation="MTHELLHLTEAPLWEAARAAGAYEMSTRGRTLREEGFVHCSLPHQ
                     LPGVARALYGPGAQGLVVLVIDADRLSAPVRFEAMDPGGEEFPHIYGPVPVDAVVEVRR
                     WQDPAGGDGPSADG"
     gene            complement(17482..17877)
                     /gene="sodN"
                     /locus_tag="SACTE_RS22315"
                     /old_locus_tag="SACTE_4493"
     CDS             complement(17482..17877)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007822186.1"
                     /locus_tag="SACTE_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4493"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_014048280.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKYQAN
                     DDADYRTRAILIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     SNDPATGQKALDLIAQIDKIFWETKKA"
     misc_feature    17934..17943
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     gene            18058..18495
                     /gene="sodX"
                     /locus_tag="SACTE_RS22320"
                     /old_locus_tag="SACTE_4494"
     CDS             18058..18495
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379073.1"
                     /locus_tag="SACTE_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4494"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_014048281.1"
                     /transl_table=11
                     /translation="MPELTQEPGGGRAVRRPFQVVEVTGPSMVPTFYHGDWLLVQYGAR
                     VRPGDVVILRHPFQQDLLVVKRAAERRGNGWWVLGDNAYAGGDSTDYGAVPEELVLARV
                     RARYRPLKNDQRSLAGVLGWAVSAVRPVSADRSVSRRLRAR"
     gene            complement(18399..19028)
                     /locus_tag="SACTE_RS22325"
                     /old_locus_tag="SACTE_4495"
     CDS             complement(18399..19028)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="SACTE_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4495"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_014048282.1"
                     /transl_table=11
                     /translation="MELAHYSDYAVRLVNTEEPARAKDSLTTVESVRELFGANAQAARR
                     ATDADVTRFRSVRARLRAVFEAADSGAETLAVDLLNSLLLEFPVSPQISGHDTRDADGK
                     PDWHMHLADHPSNATAGFAAIAAMGLAFHLTSYGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLETERSAETGRTADTAQPSTPASER"
     misc_feature    19021..19036
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.99"
                     /tool="antismash"
     gene            19118..19879
                     /locus_tag="SACTE_RS22330"
                     /old_locus_tag="SACTE_4496"
     CDS             19118..19879
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048283.1"
                     /locus_tag="SACTE_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4496"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_014048283.1"
                     /transl_table=11
                     /translation="MAEAAQITDWHSWQESWDRQQEWYMPDREERFRVMLDMVEAVVGP
                     APRVLDLACGTGSITDRLFKRFPDATSTGVDLDPALLAIARGTFEGDDRVTFVTADLKD
                     PAWTERLPHTSYDAVLTATALHWLHSEPLAELYGQVGRLVRDGGVFMNADHMIDTATPR
                     INAAERAHRHAAMDRARAEGAVDWADWWALAAEDPVLAAPTAERFRIYGEHADGDMPSP
                     QWHAATLRAAGFAEARAVWSSPSDSLVLAVK"
     gene            20004..20504
                     /locus_tag="SACTE_RS22335"
                     /old_locus_tag="SACTE_4497"
     CDS             20004..20504
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966338.1"
                     /locus_tag="SACTE_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_4497"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_014048284.1"
                     /transl_table=11
                     /translation="MRIDDDAALYAFVENRRTALFRSAYLLCGDRHEAEDLVQTALVKV
                     VLGGRRHGRLDNIEAYARKTLVNTFIASRRRFWRREQAYAELPDHAAAPTDTDTGLVVR
                     QALAGLTAKQRAVLVLRYWEDLSVAEAAETLGMRENTVKSHTARGLAALRTRMAADIME
                     ELV"
ORIGIN
        1 gcgagcgggt acgcgccacg ggagttcgag gtcgagggcg ccggcggggt gatccagctc
       61 agggcgatcc cgctcaaacc caagggcgtg cgcatcggtt cactggtgct gctgcgcgac
      121 gtcaccgaac tgcggcgacg tgagcgggag ttgatcacca aggacgcgac catccgggag
      181 atccaccacc gggtcaagaa caacctccag acggtggccg ccctgttgcg cctccaggcg
      241 cgccggatgg attccccgca gggccgcgag gctctcaacg aggcggtacg gcgcgtcggt
      301 tcgatcgcca tcgtccatga gacgctgtcc cagaatctgg acgagcgggt cgagttcgac
      361 gagatcgccg accgcgtcat cgcgatggtg gccgagatct cgccggggaa ggtcacctgc
      421 cggcggacgg gccgtttcgg gatcctggac gcggaggtgg ccacgcccct gtcgatggtg
      481 ctcaccgagg tgctgcagaa cgccctggag cacgccttcg cgatggccga gcgcggcacg
      541 gtggaggtgt ccgccgtgcg cggcggcaca ccggccgagg gccggctgct gatcaccgtg
      601 acggacgacg ggcgggggct gcccgagggc ttcgacccgc agcgcgccgg caacctgggg
      661 ctccagatcg tgcggaccct ggtcgaaggc gagttgggcg gcagcttcgg aatggtcccc
      721 gcccccggac gcggcaccca ggtcgtcctc gacgtcccgg tcagcaacga caagtgacgc
      781 ggccgtgcgg ccacggccgc acgacagtgg gcccggaccg tggtgacggt ccgggcccac
      841 tgcgtggtgc tcacggtgcg atgcgcttcg ggggtactgc gcgctgcgac tcgaaggcgg
      901 ggccgtgcgt acgctctgta cgcgccgcct ggctggggct ctgtgcgggg gcgtcggtca
      961 ggcgctggcg ttacgcgccc ggttgcgagc ggcgcggcgc ttcattgcgc ggcgctcgtc
     1021 ctcgctgagg ccaccccaga cgccggagtc ctggccggac tcgagcgccc actgcaggca
     1081 ctgctccatg acggggcagc gacggcagac ggccttggct tcctcgatct gcagcagcgc
     1141 aggaccggtg ttgccgatgg ggaagaacag ctcggggtct tcctcacgac aaacggcgtt
     1201 gtgacgccag tccatggctg ctacctctcc ttggtattac atgctggtgc ttgtgaatgt
     1261 gaacgctttc acgaatcccc ccgcagacga aggtccgacg cccagatgaa ctggttgtgg
     1321 tcctgttgtg gtgaggaggg gttctggctc tcagggatgc cggtgttgcg ggctgtcccg
     1381 atcgccatgt agagattcgc aaacctcggc ggcggataca accccttctg gaaagttttt
     1441 tttgattcct cggtgtcgac taggtcacag ccgcacttct aaggggtggg gcccagtcca
     1501 aacgttcgag ttaaaggact ttgggccctt ccactcacac aatcacacgc agtgcacggc
     1561 gtacgcctgt gaacgtcacg ctcgtacgca gtcccaggtg gtcgccgtcc atctggaagg
     1621 gcagtggagc cttcgaatgc aaggtgaagt cggtgaggtc gtgcagggag accgcgtgct
     1681 tgccgtgcgg gcccttctcg gggctggaag tcagcagctg ggtggcgtac cgggtcaccg
     1741 cggcggtgga caggcggcgc agtcccagga tgtccagccc ggtgtcgaag gaggctctgg
     1801 gggccgcgta catcggacga ttccccaggt aggtccaggg ggcggtgttg cagatgatgg
     1861 acagcgcgag gtccgtcacc gggtcctggc cgggggcgtc cagggtgatc aggccgtcgc
     1921 ggcggtgcgg ttcctcgagg aactggcgca ggacctggcg gacgtacagc gcgtgggtcg
     1981 aacgcttgcc gcgctcgcgc ttctgttcga cgcggccgat gaccccggcg tcgaatccga
     2041 ggcccgcgca gaaggtgaac cagcgttcgg gtacggcctc gtccggggag cccggggtgc
     2101 cggccgccag gccgaggccc accgtgcgct cgctgcggtc cgcgagggcg tccaggatgg
     2161 cgccggtcgc ttccacggcg tcgttcggga tgcccagggc gcgcgcgaag acgttggtgg
     2221 agccgccggg gacaacggcg aggctcggca ggttctccag gtcgggcccc ttgtggagaa
     2281 ggccgttgac cacctcgttc accgtgccgt cgccgcccag ggcgaccacg atgtcgatgt
     2341 cgtcggagtc cgcggcccgg cgtcccaggt cccgggcgtg cccgcggtac tccgtggtca
     2401 cggcctccag cttcatctcg ctcgccaggg cgtggatgag cacgtcacgg gtccgcgcgc
     2461 tggtggtggt ggcggctggg ttgaccacga ggagtgcgcg catgcggtca gcctacctac
     2521 cgtgcggtac cgcccagaag cgccggatct cccggtccac ggcccgtcac cctgcgtgac
     2581 agggtccgtc cggcgcgtcg gccgcggacc cggcttcgct tccggggggc ggagatgcca
     2641 acctgaagga cgtgagtact gaagcgaacg cgccctctcc gtcgccctcg gccggcgagg
     2701 agaagccggg ccggatcacc ctcgtggccg ctctgaacgc cctcgaaggc gccgcgctcg
     2761 ccctcggcgg ggtctacatg ctggtcatgg gcctgctggg gcggcccgac agccctcagc
     2821 aggcggagat gggcgggctg acgctggtgg ccctcggcct catcccgctg ttcgccgccc
     2881 gggggctgct gctgcggcgc agctggagcc gcggccccgc actcatcacc cagctcatgg
     2941 ctctgccggt ggcctggacg ctgctgcggt cgcagggtgc gctgatcccc gccgggatcg
     3001 tgctcgccgt ggtcgccgtg acggggctgg tgctgctggt cgatccggcg accactcggg
     3061 cgcttggcat ccgggggccg cgagcgaccc ccgacgcctg aggcgacgac ccccgccgcg
     3121 gcctcctact cctcgacgag cagccgttcg cggagctggg cgagggtgcg ggccagcagc
     3181 cgggagacgt gcatctggga gataccgacc tcctgggcga tctgcgactg ggtcatgttg
     3241 ccgaagaacc gcagcagcag gatgcgcttc tcccggggcg ggagcccctc cagcagcggc
     3301 ttgagcgact cccggtactc gacgccctcc agcgcctcgt cctcggagcc cagggtgtcc
     3361 gcgaccgcgg gcgactcgtc gtccgtgtcc gggacgtcca gggagagcgt gctgtaggca
     3421 ttggccgatt ccagcccctc cagcacctcc tcctcggaga tgcccaggcg ctccgccagc
     3481 tcgtgcacgg tcggcgaccg gccgtactgc tgggagagct ccgcggtggc cgtggtcagc
     3541 gacagccgca gctcctggag gcggcggggc acccgcaccg cccagccctt gtcgcggaag
     3601 tggcgcttga tctcgccgac gaccgtgggg gtggcgtacg tcgagaactc gacgcctcgg
     3661 tccgggtcga accggtccac cgacttgatg agcccgatcg tggcgacctg ggtgaggtcg
     3721 tccagcggct cgccccggtt gcggaagcgg cgggccaggt gctccacgag cggcaggtgc
     3781 atccgcacca gccggttgcg cagctccgcc ttctcggccg aaccgtcggg cagctcgcgc
     3841 agctccacga agagtgcccg tgccccgctg cggtcgtgtg gatcgtggtg cccgtgctcg
     3901 ctcatctggc ccgcccgctc cgcctgcgac tgctccaccg cgaccgtacg gccccgcgcc
     3961 ccgtccacgc cgccggccgc gtccgcgccg tccaccggat gcggccgggc ctgttgctcc
     4021 gggacggcgg ctgggcgcac cacctcggac cggatcgtct cgtcacgcac aggcccgtcc
     4081 ccgttcccgt tgctcacgcc ggcccgggtc ccgcgccgcg ctgtttgtag aggctgatgc
     4141 tcaccgtgcg gtcgtcggcc accgtggagt cgaccttgcc cgcgagcgcg gagagcaccg
     4201 tccaggcgaa ggtgtcgcgc tcgggggcgc gtccgtccgt cgtgggtgcc gagacggtca
     4261 cctcgaggga gtcgtcgatg agacggaaga cgcagctgag gaccgagccc ggcacggcct
     4321 gctggagcag gatcgcgcag gcctcgtcga ccgcgatgcg aagatcctcg atctcgtcga
     4381 gggtgaagtc caagcgcgct gcgagaccgg ccgtggccgt acgcagcacc gacaggtagg
     4441 cacccgcagc gggcagccgg acctctacga agtcctgatt cccgggctcg cctgcgatct
     4501 gggacaccct cacctccaag gtggcacaaa ctcgttcgag gctccgggac gcgtgcccgg
     4561 ggccatccgg tccgccgccg gtgtgtggtc cggcggcgtt gtcgcggtcc atgatgccgt
     4621 gtcgccgcga ccccgtccct gaccgtcact catggtaagc atacgcgtac gcacagttgc
     4681 taggggtctg cggcggtcaa ttgcgaagaa ccggcgccgg tttgacgtac ccaggcgtca
     4741 cacgatcgaa ccgtcctcga agcaccagcg ccagttctcg ccttcttcga agctgcgcat
     4801 caccgggtgc ccggtggccc ggaagtgctt cgtggcgtgc ttcagcggcg aggaatcgca
     4861 gcagcccaca tgcccgcaga ccaggcagag ccgcagctgg accggatggg tccccgcctc
     4921 caggcactcc cggcacgtgt cgctgagcgg ggagggctcg gggcgcggca gttcggatac
     4981 gtggcggcac tcactcatga tggccacgtt acgtcggatg cgaggacggt gagatggacg
     5041 cgctgcccct ggtggcactc gtcgcggcca gcgcggcggt cgcgggtgcc gcgcggcgga
     5101 ccccggtgcc cgcaccactg ctgctggtgg ccgtgggcct gctggtgtcc tacctccccg
     5161 gggtgccgca cttcaccctg gacgcgcaca tcgtgctgcc gctgctgttg ccgcccctgc
     5221 tgtacaccgc cgccgtcgac agctcgtacc tcgacctgcg ggccaacgtg cggccggtcg
     5281 cgctgctctc cgtcgggtac gtgctcttcg cgaccttcgc cgtgggcgcc ctggcctact
     5341 ggatcgtgcc ggacctgccg ctcaccgccg cgctggtgct cggcgcggtg atcgccccgc
     5401 cggacgccgt caccgccgcg gcgatcgccc ggcgggtcgg gctgcccgcc cgggtcacca
     5461 cgatcctcca gggcgagtcc ctggtgaacg acgccaccgc gatcaccgcc ttcaaggtcg
     5521 ccctcgccgc ggccgtcggc gagggcatga gctggggtgc cgggatcgtc gagttcctgc
     5581 tggccgcggt cggcggcgtc ggggtcggcc tggtgctgat ggtcccgctg cactggctgc
     5641 gcacccacct cggcgaggcg ctgctccaga acaccctctc gctgctgatc cccttcgtgg
     5701 cgtacgcggc ggcggagcgg gtgcacgcct ccggggtgct ggcggtggtc gtcgtcgcgc
     5761 tgtacctggg gcaccggtcc tggcaggtgg acttcgcgac acggctccag gaggcggcgg
     5821 tctggaagat ggtcgccttc gtcctggagt cggcggtctt cgcgctgatc ggcctccagc
     5881 tgcagtccgt ggtcaggggg ctgggtacgt acggcctgac cgacgccgtc cggtacgcgc
     5941 tggccgtctt cgtcgcggtg gtgctggtgc gcttcgtctg ggtgtacccg gcgatgtacc
     6001 tgccgctgtg gctctcccgc cgcatcaggg agcgcgaacc cgcgatgccc tggacctcgc
     6061 cgctgatcgt cgcctgggcc gggatgcgcg gggtcgtctc gctcgccgtg gccgcctccg
     6121 tcccgctggt cacgcacgac ggggagcact tcccggaccg caacctcctg ctcttcctga
     6181 ccttcacgac ggtcatcggg acgctggccg tccagggact caccctgccc ctcctggtgc
     6241 gggtgctgaa gctgccgggg cgggacgcgc gcgccgagac gctggcggag gcgcaggcgc
     6301 agagcgaggc gtccacggcc gccgaggccc gcctggacga gctgctctcc gatccgcaca
     6361 actccctgcc cggaccgctc tccgaccggc tgcgccatgt gctggagcgg cgccgcaact
     6421 ccgtctggga gcggctcggc gccgccgacc cggtcaccgg ggagtcggcg gacgacacct
     6481 accggcggct ggccagggag acgatcgacg ccgagcggga ggtcttcgtg cggctccggg
     6541 acgaacgccg gatcgacgac gagatgctcc gggtgctgct gcgccggctc gacctggagg
     6601 aggccgcggc ctaccgggag cccgacggct cgacctgagg cccctgaggg gcgtcggggc
     6661 gcccggtgac gacggcggtc accgtggagc ccggggcgaa cgcgccctcg cccgccagca
     6721 cggtcagggc gtacagcagt ttcgcgacgt agaggcgttc gacgggcagg ccgtgccggt
     6781 cctcgaagtc gtcggcgaag gcgtgcagcc cggcggtcgt acgggcgtag ccgccgaagt
     6841 ggaagcgctc gtccagggac caccgccccg ccgggccgcc gaacgcctcc tcctgcagcg
     6901 cgcgcaccgt ctcccccagg aagccgccgc gcagcacggg tatgcccagg gcgtgctgct
     6961 ccgggccgag cccggcggcc agcccggcga gggtgccgcc ggtgccgcag gccaccgcga
     7021 cggtaccggc gggtccgcgc agttcgcggc cgagctctgt gcagccccgt acggcgagcg
     7081 cgttgctgcc gccctccggg acgacgacgc actccccgaa gaggctcagc aggccgtcca
     7141 ggacctcggg agaggtcttc gcgcggtagg tggagcggtc cacgaagtgc agtcgcatgc
     7201 cgtcggccgc gcaccgggcg agcgaggggt tcagggggcg gtgggccagt tcgtcgccgc
     7261 ggacgacgcc gaccgtgggg aagcccagca gccgcccggc cgcggcggtg gcgcgcagat
     7321 ggttggagta ggcaccgccg aaggtcagga cggtgcggcc ggcggcggcc cgcagattgg
     7381 gacccagttt gcgccacttg ttgcccggca ggtccggatg gatcaggtcg tcgcgcttga
     7441 gcagcagcgt caccgagtgg cgggtgaagc gctcgtcctc gaccggctcc aggggtgagg
     7501 gcagggcggg ccgcagccgg gagaggtcga gcgcttcgtc gtgcatccgg gcattgtctt
     7561 ccgcgcccgt gcccggcagc tacttgaggt gttcccggac acgggcgcgc atcccgttca
     7621 tcgagaagcc gcgcgggtcg acctttccgg gctgccactc caggtgcccg atcaccgagg
     7681 aggcgcccca gcggtggaag cggcagagcg cggccgcggc cttcccgacg gcctcaagct
     7741 gggcggcggg ccacgggtcc tttccgtcgc cgaggttctc gcactcgaaa ccgtagaagt
     7801 gccggttgcc gtcggcgccc gaatcgtcga cgtcggggag ccgcttctcg gcgacgacgg
     7861 cgcgcaggac gtcgtcgtcg ccgagaccgg cgtggttgac gcggccgtag ccgaccaggt
     7921 ggacccggcc gtccttggtg atcacgccgt ggcagagcgg gccgggcagg ccggtgcgcc
     7981 cctcgcggca cacgtcgacg gtccgggcgg agccctccgt ggcggtgtga tggagcatca
     8041 ccccgtgcac cggcccccag gaacctttgt cgttgcggtt gtgggtgcgc cagtcgccca
     8101 cctggacgac ggtcaggccc tcgtcctcga gggccttgag gaatttgttc gcggacatcg
     8161 gtgaggacat ggccggctcc ttcggttcgc ggggagggtg tccgtactgc gcttgtaccg
     8221 gaacgcggtc ctccggacca ccggtccggg ctctgtgcga agccctgtgc gagccgatcc
     8281 ggacaggtgg agggcgggac ggggacactc cctcgtccgg cggctcgtcg ccgcgcggca
     8341 cgcacggccg ggcgcgccga tgtgccccga ctgaaggccg aataatcaca ctcttttgtg
     8401 taatagcgcg ccgtgttccc cagctgaaag gcttcttcac gcagttcagc ccatgatcga
     8461 gaggatgtcg gatgtccgtt ggtgaagagg ttcgcgacac gcagccgccg cagcagagtc
     8521 tcggcacggc ggccgcgcgg aacctcgcga cgacgaccaa gtccgccccg cagatgcagg
     8581 agatcacctc gcggtggctg ctgcggatgc tgccgtgggt gcaggtgcag ggcggcacct
     8641 accgggtgaa ccggaggctg agctactcgg tcggcgacgg ccgggtgacc ttcgtgcaga
     8701 ccggtgacca ggtcgcggtc atccccgccg agctcggcga gctgccggcg ctgcggaact
     8761 tcggggacga ggaggtcctg gccgagctgg cccgcaggtg cgaacagcgt gaagtggcgc
     8821 cgggtgagct gctcacgatg tcgggggagg cggcggaccg cgtctacctg ctggcccacg
     8881 gcaaggtgga gaagatcggt tccgggctgt acggcgacga gacggtgctc ggagtcctcg
     8941 ccgacggcgc ctacttcggc gaccacacgc tggtggacgg cgacgccacc tggtcgtaca
     9001 cggcacgtgc cgtcacggcg tgcacccttc tgacgctcag ccgtgccgac gtactgaacc
     9061 tggcggcccg cgccgactcg ctccgtgacc atctcgccgg tctgctggcc attccgcacc
     9121 agcgcaccaa ccactacggc gaggcggaga tcgacctctc ggccggacat gtgggggaga
     9181 gcgtcgtccc gcacaccttc gtcgactacg aggcggcgcc ccgggagtac gagctcagcg
     9241 tcgcgcagac ggtgctgaag gtccacagca gggtggcgga cctctacaac cagccgatga
     9301 accagaccga gcagcagctg cggctcacgg tcgaggcgct gcgcgagcgc caggagcacg
     9361 agctcatcaa caaccgggag ttcgggctgc tcaacaactg cgactacggg cagcggatcc
     9421 agccccacga cggggtgccc agccccgacg acatggacga actcctgtcg cgccggcgcg
     9481 gttccaagct gttcctggcc caccctcggg ccatcgccgc cttcggccgc gagtgcaaca
     9541 agcgcgggct ggtgccggag agcgtggagg tcggcggaca ccacgtgccc gcgtggcgcg
     9601 gggtcccgat cttcccgtcc aacaagatcc cggtcacgga cgcccggacg acgtcgatca
     9661 tctgcatgag gaccggcgag caggagcaag gagtcatcgg actccagcag agcggcatcc
     9721 cggacgagat cgaaccgagc ctgtccgtcc gcttcatggg catcgacgag caggcgatca
     9781 tctcctacct ggtgacggcc tactactccg ccgcgatcct cgtgccggac gccctcggtg
     9841 tcctggagaa cgtcgaggtg agccgctggc ggtgacgtac gcgcccgggc ggacggcagc
     9901 cgcccgggcc gcggagcccg ggcggcgcac ccgcccgggc ccgtacgcgc acgccgcgac
     9961 cagggtgcct tcgaggcgcc cggaaggagt gaccgtgacc atgacgagta cggacgccgc
    10021 gacggaggga caggaggccg cagtactcct ggagcgcacc cgcggcctcg tggacccgca
    10081 cctcagggcg gcggtggaca cgctgcccgg ggcgatacgg cgggtcgccc ggtaccactt
    10141 cggttggcag aacgccgacg ggacacccgc atccgggcag gcgggcaagg ccatcaggcc
    10201 cgcgctcgtg ctggccgccg cccgcgcgct gggcggcgat ccggagtcgg ccctgcgggc
    10261 cgccgtcgcc gtggagctgg tccacaactt caccctgctc cacgacgacg tcatcgacga
    10321 ggacgcgacc cggcggcacc gtcccacggc atgggcggtg ttcggcgtcc cggacgcggt
    10381 cgtcaccggt gacgccgtgc tcgcgctcgc ccagcggctg ctggccgagg acccgcaccc
    10441 cgggtccgcc cgtgcctcgg cgcggctctc cgcctgcgtc atcgaactgt gtgccggaca
    10501 gcaggccgac tgcgcgctgg aggagcgcga acccctcgac gtcaccctcg acgagtgcct
    10561 cacgatggcg acggccaaga cgggcgccct gctcggctgc gcctgcgccc tcggagcgct
    10621 ctacgcgggg gcggacgagc cggccgtcga ggccatggac ggcttcggca gggaggcggg
    10681 cctcgccttc cagctcatcg acgacctgat cggcatctgg ggcgacaccg cccgcacggg
    10741 caaaccggtc ggcgctgatc tcgccgccca caagaagtcc ctcccggtgg tggccgccct
    10801 cacctcgggc acgcccgccg ccgacgagct cgccgtgctc taccgcgggg ccatgaacac
    10861 ccccgccgag gtgtccgggg cggcggcagc ggtcgaccgg gccggcggcc gcgactgggc
    10921 ccaggcctgt gcggcggacc ggatggcgcg cgccgtgcac cacctctccc gcgcggtgcc
    10981 tgatccggcg gccgcgcagg atctgctggc actggcggag ttcgtgaccc gcaggacgca
    11041 ctgagcgggc cgctggtgac cggccggtgc ggtcaactct aggatccctt cggtcggttg
    11101 agatcatcac ggcgggacgg aagggacggg gccggtcatg ggcgtacgcg tgcggcaggc
    11161 ggacgggcgg gacagggatc aggtcgtgga gatcatggag gcggcgttcc accacgatcc
    11221 ggtgagcggc tgggtcttcc ccgacgagga gcaccggcgg gcggtgcacg ggaagttcct
    11281 cggcgtcttc gccgacgtcg cgctgtccga ggggcgtgtc gacctgctgg aggacggtac
    11341 ggccgtggcc ctctgggtct cggtgcccgc cggggctccc gaggccgagg acgacacccc
    11401 ggcgctcatg cggcggacgg cggacccgga caacgagcgg gccgagctgg tgggccggct
    11461 caccggcgcc gtccacccgc acgaccgggc ccacgcctac ctgctgatgg tcggcgtccg
    11521 cccggagcac cagggggagg ggatcgggga ggcgctcatc ggcggcgccc tggagcagtg
    11581 cgaccgtgag ggcgtgccgg cctatctgga ggcgagcagc gagcggagcc gcggcctcta
    11641 cgagaggctc ggattcacct tcacgggacg gacggtggag cttcccgacg gtccgtcgat
    11701 gtggcccatg tggcgcgaac cgcaggccgg gaggtaggac ccgcaggccg ggcggtggaa
    11761 gggggaggtg gccggagcgg gggaggggac gggggctaca gtccctgccc atgacagatg
    11821 agtcgtgggc aggctggtac cgggaccgcc gtggttccga ggccttcatt ctcaccacgg
    11881 acgggcggcg actccgcgtc cgggtccggg ggacggactt cgagggggag agcttcgacg
    11941 ccctcctccc ggcggccggg gtggtgccgg aggccggtgc gttcgacctg gccgacgggg
    12001 tgctcggcga ctgtgtgctg gagtgggacc tgcccctccc ggtcctcgcg gcaggaacgg
    12061 tccgtcaggc cacgctcagc tgcctgctgt ccctgcgccg tgccgatccg gatctgtacc
    12121 tcgcgctcca cctggacgga gcggtgtacg agtcccaccg ggcggagaac gacttcgctg
    12181 cggcgctggc cacgatccgg gccgtcctcc ccccggacat acaactgcag atatgcaccg
    12241 cctgcgccct ctccggctac ctccccgcgt ccggccgggg catctccggg ggactcggct
    12301 gcttccgcga cgcgaaggac gcctaccggg acgtgacgga ggggtccgcc gtcgccgggc
    12361 tgtgggaccg gcggaccgga ctggtccagg agatatggag ctgccgggag ttcgaaccgc
    12421 ggccgttcga gccgggcctc gtcaccgggg ccccggccga acggcgtacg ggcgccccgg
    12481 gaccgacgga gggagccggt gccggccggc tgggcgttca cccgctcgaa cacgcctgac
    12541 ggcacccgac cccgaagcca ccgccccgta ccggaccgcc ggtacggggc ggtgccgtgt
    12601 ccggagggcc acagggcgtt gtcatgtttg cattgttcta ctaacatgcg aacaacggag
    12661 gtgctcatga accctaagaa gctcgggcgc gcggtcctcg tcgccctgcc gttccttgtc
    12721 gtcctgatcc tcgccctcgt cctcgccggc acgctctcgg accggctgcc cggccggttg
    12781 gccacgcact tctcggccac cggtgaggcc aacgggtaca cgggccgcac gacgttcctc
    12841 gtcctcaccg ccctggttcc ggcgctgctc ggcgcctgct ggacctacat ggccgtcagg
    12901 ggccggttcc acggccgcgc gtacgacggg ttcaccgcgg ccgggtacgc gaccgccgcg
    12961 ttcttcggct acctgacgac ggtcacgctg ttcgccaacg tggacacggc cgacggtgcg
    13021 ccgggggcga cgttcacgat gtggcacctc gtgggcgcct tcggttcggc cgccgtcgcg
    13081 gcagccctcg gctacttcct cgcgaggctg ctgccggccc tgccggacga cccggaggcc
    13141 gctgccgccc gggagggtgc ccgcatccca ctggccgacg gagaggtcgc cggctgggtg
    13201 cggagcatgg cgtcctggtg gctgccgggg accgctctgg cgatggtgct cgccggtgtc
    13261 gtcctgacgt tcgccctgcg gccggtcacc ggcctgcccc tgatggtcat cggcctggtc
    13321 ctcctgccct acagccggcc gaacgtcacc gtggaccgcc gcggtctcat cgtctccgga
    13381 ctcctgccct ggccgcgcgt ccacgtaccg ctggagcgca tcgacaccgc cacgagccgg
    13441 aacgtcaagg ccgtggcgga gtacggcggg tggggctacc gcgtccgcgc gacccgctcg
    13501 ggcgtgatca ctcggtccgg ggaggcgatc gtggcccggc tggagaacgg gcgcgacttc
    13561 gccgtgacgg tcgacgactc ggcgaccggg gccgccttgc tcaacaccct ggtcgaccgt
    13621 cggcgaggga ggagctgacg gtgctgttcc gggtcgaccc ctcctcctcg gtgccgctgg
    13681 gcgaccagat cgccgcatgc gtccgccgtg ccgtctcgga cggatcggtg gctccgggtg
    13741 agcggcttcc ggcggcgcgc gcgctcgccg actccctggg cgtcaacgtc cacaccgccc
    13801 tgcgcggcta tcagcggctg cgcgaggaag gcctgatcga gctgcgccgg ggccggggcg
    13861 cggtggtcac cgccggcgcc tccccgcacc gcgcccggct gctggagggg gtgcgcgccg
    13921 tggtggcgga ggcccgggag ctgggactgg cggagggtga tctgctggat ctggtccgcg
    13981 cggagctgaa cgcctgaacc ccgcaccccg tgccgcgggg gccgcccctc ccggagcggc
    14041 ccccgcgcca tgagcgggat caggagccgg cgcgtgccag ggcggccgcg atgccgttct
    14101 gccagaggga gttcacccgg gagcgctcgg tggcgtccgg gtaggcgttg gtgcaggagg
    14161 ggccggggcc accgcccgac atcagctcgc tgcacggccc gctgtagtgg tccggcaggc
    14221 cgagcacgtg cccggtctcg tgcgtggtga cccgggtcga gtcgtactgc tggttctggg
    14281 cgtagtcgag gaagacgtac ccccggccgt gcccgtcggt gctggcgtag gaaccgcgcg
    14341 cgtcgttgcc ctcgtagtag acgaagtccg cgttcgagcc ctcctggagc ttcacgttgc
    14401 cgaccgagct gttccagatg gacgcgctgc tcgctatctg gctgcggaag ctgggcgcct
    14461 gggcggcgct gtagaccacg gtgaccgcct gggcgccggg cacggcggcg cgcttctcgg
    14521 cgaccgactt catgacggcc tcgaagaacg cctggttcgc ggcggcgttc tcgctcgaac
    14581 cggcgtacgc agcgtagccg ttcgtggtgg aggtggaggg cgcggagtgg gccggggcgg
    14641 tggcggccgc gggggaggcg ccgagcgcca cggcgaggcc gagaccggcg acggccgaca
    14701 tgaggacggt cctggggtgt ctcatggggg ggttctccta cctgtccgat gaaccccgtc
    14761 cgaggacggg gaacgggtgg ggggtacgga gagagtgtcg ggccgcccgg ggcggtcgcg
    14821 gatgatgtca accggcgata gcgccgccct atcaccggca caggaacgac acagcacccg
    14881 cacatggaca tcgccccaac agcccctgaa tcggcctgtt tagcggcatt ggatcccctg
    14941 gtgcttcccg tgtgcacggt catacgctca tcgccatgga gttcgaggtg agacacctca
    15001 gggcgctctg cgccatcgcc gacacgggca gcctgcacca ggcggcacgg cggctgggcg
    15061 tcagccagcc cgcgctgact acccagctcc agcggatcga gaagtccctg ggcgcgtccc
    15121 tcttcagccg cgagcgcacc ggctgccggc cgaccctgct cggccgctcc gtcctgagcc
    15181 gggcccgccc actggtcgac ggcatggcgg ccctggtcga cgccgcactc gccgaggccg
    15241 aggcggcccg cgagggcggc ccccggctgc gcatcgggtc caccgcgagc cgggtcatcg
    15301 gcggctggct gcgccggctg cggatacggc tgcccggtac cgacatctcg ctccgggtcg
    15361 acgtctcggc ccgggagctg ctgcgcgcgg tggcggcggg ccggctcgac gtcgcgttcg
    15421 tgcacgaggt ggagggtttc ccgctgaccg tcccggaggg cctggggcag cgcgtactcc
    15481 tggagcggga accgcagttc atctccctgt cgcgcgatca cccggcggcg gcccgcccgg
    15541 tcgtggacct ggacgacctg gcgggcgacc gctggatggt cgatccctcg gtcgacggcg
    15601 agtgggacgg ggtgcgccgg gtactgggcg cggcgggtct ggacccgccc gtgctgcacg
    15661 gcgactacct cacggcggcg tccctcgtcg tcctcggcga ggcggtcgcc ccctgccagc
    15721 ccacctcggg gccgcgcgag gacatggcga tccgcccgct gcgcggcgac ccgctggcgg
    15781 tacggctgct gctggtctca cgcccgggga ccgacacgga cacggtgtac gcggagctgg
    15841 aggcggccta ccgcgaggcg gcgcgacgcg ccgccgcgta ccaccagtgg ctgctgcgcc
    15901 accgcagtcc gctggtcgcc gtggactgac ggccggggtt ccccgttctg ccgacagcag
    15961 ggcgccgttt cccgtacgga ggaccgcggg caggaccgtg ccatgaggat cctgatgctg
    16021 ggcggcacgg agttcgtcgg ccgcgccgcc accgagacgg cgctcgcacg cggttggcag
    16081 gtcaccgtat tccaccgcgg ccaccacgcc ccgccccccg gcgtacgggc gctgaccggc
    16141 gaccgtacgc ggggcccggc ggggctcacc gccctggaga gcggtacgtg ggacctggtg
    16201 gtcgacacct ggagcggcgc ccctcgggcg gtgcgggacg cgacccggct gctgtcgggc
    16261 cgggccgggc acttcgcgta cgtctccagc cgctcggtgt acgcctcgcc gagcccgccc
    16321 ggacgggcgg aggacgcccc gccggtggag ggcgcgtccc ccgacgcggg cggggacgtc
    16381 tcctacgccc tggccaagcg gggcggtgag ctcgccgcgg tcgacgcgtt cggcgaccgg
    16441 gccctgctgg tccgtgccgg tctgatcctc ggccccgggg agaacgtcgg ccggctgccg
    16501 tggtggctgg ggcggacggc ccgtggcggc ccggtgatcg caccgggacc gcccggggcc
    16561 ggcatccggt acgtcgacgc acgggacctg gcgagctgga tgctggacgc ggcggcgcga
    16621 ggcctcggcg gcgcgtacga cgtggtcggc gggccggggc acgccaccat gggcgagctg
    16681 ctggacgcct gtgtccgggt gaccggctcc ggcgccgaac tgcgctggac cgatcccgag
    16741 gtgctgctcg ccgccggggt ggaaccgtgg accgacctgc ccgtatggct gcccgccggt
    16801 gagctgtacg acgccgtcca ccaggccgac gtcaccaagg cgtacgcggc cggcctgcgc
    16861 tgccggcccg tcggcgagac cgtcgccgac acctggtcct ggctgtgcgc acggggcggc
    16921 actgcaccgc agcggcccga ccgccccggg gtcggcctcg acgcgaggac ggaggcgagg
    16981 cttctcgccg gtgagggggc gccgtaacgt ggccggatga cgcacgagtt gctgcacctg
    17041 acggaagcgc ccctctggga ggccgcccgc gcggccgggg cctacgagat gtccacccgg
    17101 ggccgcaccc tccgggaaga gggattcgtc cactgctcac tgccccacca gctccccggc
    17161 gtggcacggg cgctgtacgg tcccggcgcc cagggcctgg tggtgctggt catcgacgcg
    17221 gaccggctgt ccgcacccgt gcggttcgag gcgatggacc ccggcggcga ggagttcccg
    17281 cacatctacg gcccggtccc ggtggacgcc gtcgtggagg tccggcgctg gcaggacccc
    17341 gcgggagggg acggcccctc ggccgacggg tgagccgggc gtagggcgag cggcgcacag
    17401 ggaagggccc ggacgcctca ggcgtccggg cccttccccg cggtggaccg gcggtccggc
    17461 ctcggccgga caggaggccg gtcaggcctt cttggtctcc cagaagatct tgtcgatctg
    17521 ggcgatcagg tccagggcct tctggcccgt ggccgggtcg ttcgagccct tggccgcgga
    17581 gagcgccttc agggtgtcgt tgaccagctg gtgcagctcc gggtacttct cgaagtgcgg
    17641 gggcttgaag tagtcgctcc agagcaccga gacgtggtgc ttcgcgagct cggcgcgctg
    17701 ctccttgatc aggatggcgc gcgtgcggta gtccgcgtcg tcgttggcct ggtacttctc
    17761 ctggacggcc ttgacggact cggcctcgat gcgggcctgg gccgggtcgt acacgccgca
    17821 gggcaggtcg cagtgcgcgc tgaccttcac cttgggggca aacaggcggg aaagcatgga
    17881 gctgtccttc ctcgtgatcg tcttctcagg tgggacatta ctccgtgggg gagtcttttt
    17941 tgcgcctgcc cccgtgggct taggccaaaa gtccagggtg aggatgagac cagtggccgg
    18001 atgtacgaaa cggtacgcac ggcggtgtac tggaggacgg accgggaggt gccacggatg
    18061 ccggagctga cgcaggagcc cggaggcgga cgggcggtgc gcagaccgtt ccaggtggtg
    18121 gaggtgacgg ggccctcgat ggtgcccacc ttctaccacg gggactggct gctcgtgcag
    18181 tacggggcgc gggtgcgccc cggcgacgtg gtgattctgc gccacccgtt ccagcaggac
    18241 ctgctggtgg tgaagcgggc ggccgagcgg cgcggcaacg ggtggtgggt gctgggcgac
    18301 aacgcctacg cgggcgggga cagcacggac tacggcgccg tgcccgagga actggtgctg
    18361 gcccgggtgc gcgcccgcta ccggccgctg aagaacgatc agcgctcgct ggccggagtg
    18421 ctcggctggg ctgtgtccgc ggtgcgtccc gtctccgctg accgctccgt ctccaggcgc
    18481 ttgcgggccc ggtaggccgc cacgttggcg cgggtcgcac agcggtccga gcagtagcgc
    18541 cgcgagcggt tggtggaggt gtcgaggtag gcgttgcggc agggggccgc ctcgcacagc
    18601 ccaagccggt ccacaccgta cgaggtgagg tggaaggcca ggcccatcgc cgcgatggcg
    18661 gcgaaaccgg ccgtggcgtt cgacgggtgg tcggccaggt gcatgtgcca gtccggcttg
    18721 ccgtccgcgt cacgggtgtc gtggccggag atctgcgggc tcaccgggaa ttccagcagc
    18781 agggagttca gcaggtccac ggcgagtgtc tcggcgccgc tgtcggccgc ctcgaagacc
    18841 gcgcgcagcc gggcccgtac ggacctgaag cgcgtcacgt ccgcgtcggt ggcgcgtcgg
    18901 gcggcctggg cgttggcacc gaagagctcg cgcacggact cgacggtggt gagcgaatcc
    18961 ttggcgcggg ccggctcctc ggtgttcacc agacgcacgg cgtaatccga gtaatgggcc
    19021 agttccactt gtagtcctta cggcatcggt ctagggtcgc tgttgtcgac cagtgtaatg
    19081 gtcgagcatg cttactgggc attacgtgga ggttgggatg gcggaggctg cgcagattac
    19141 cgactggcac tcctggcagg agagctggga ccggcagcag gagtggtaca tgccggaccg
    19201 cgaggagcgg ttccgggtga tgctggacat ggtggaggcc gtcgtggggc ccgcaccgag
    19261 ggtcctcgac ctggcgtgcg gtacgggaag tatcaccgac cgcctcttca agcggttccc
    19321 ggacgccacc agcaccggtg tcgacctgga ccccgccctg ctggccatcg cccgcggcac
    19381 cttcgagggc gacgaccggg tcaccttcgt gaccgccgac ctcaaggacc cggcctggac
    19441 ggaacgcctc ccgcacacct cgtacgacgc ggtcctgacc gccacggccc tgcactggct
    19501 gcacagcgag ccgctcgcgg aactgtacgg gcaggtcggg cgactggtcc gtgacggcgg
    19561 ggtgttcatg aacgccgacc acatgatcga cacggcgacc ccgcgaatca acgccgccga
    19621 acgcgcgcac cggcacgccg cgatggaccg cgcccgggca gagggagccg tcgactgggc
    19681 cgactggtgg gccctggccg ccgaggaccc ggtcctcgcg gcgccgaccg ccgagcgctt
    19741 ccgcatctac ggcgagcacg cggacggtga catgccctcc ccgcagtggc acgccgccac
    19801 cctgcgcgcc gccggcttcg ccgaggcacg cgcggtctgg agctcgccct ccgacagcct
    19861 ggtcctcgcg gtcaagtagc cggcaccgaa aggagtcagg gacggccctg actcctttcg
    19921 tgtgcccgca acctcccgcc gggcccaccg cactggaagg gtgagacggt ccgcgcccgc
    19981 gggcccggag aggggcgccg acgatgcgga tcgatgacga cgccgcgctg tacgccttcg
    20041 tggagaaccg ccgcaccgcg ctgttccgca gcgcctacct gttgtgcggc gaccggcacg
    20101 aggccgagga cctggtccag acggccctgg tcaaggtcgt gctcggcgga aggcgtcacg
    20161 gacggctcga caacatcgag gcgtacgcac gcaagaccct ggtcaacacc ttcatcgcga
    20221 gccgccgccg gttctggcgg cgtgaacagg cctacgcgga gctgcctgac cacgcggcgg
    20281 cgccgaccga cacggacacc gggctggtgg tgcgtcaggc gctcgccgga ctcaccgcca
    20341 agcagcgtgc cgtgctcgtc ctgcgctact gggaggacct gagcgtggcc gaggcggccg
    20401 agacgctcgg catgcgggag aacacggtca agagccacac ggcccggggg ctggcggcgc
    20461 tgcgcacgcg gatggcggcg gacatcatgg aggaactggt atgaacgacg tgcgtgaact
    20521 gctggcacgg gccgcccggg acgccggccg cccggcggtc tccaccgggg cggtgtacgc
    20581 cagggccgcc cgggtccgct tccgccgccg ggcgggcgtc gcgggggccg cgctcgcggt
    20641 cgtcgccacc gggggagtgg ccctgcccca gctgaccgac ggcacgccca cgggcacctc
    20701 cgtcgcggcg gccccggtcg ccacggcgag cggaggcgac aaggccggcc ggctggccgc
    20761 cctgctgccc gaggccgtgg gcggcgtcga gcaggtctcc ctcgccgccc tgatcaaggg
    20821 cgtgcccccc gagcatgccg gggagacgta cgtcggcccg ctggacgggc agtacctgat
    20881 ccgcgaggac ggcggtgccg gctatctgac cctgtcgttc atgaagcccg cccaggtgga
    20941 gaggaagttc ggcggaagcc tcggcggcga cctgtgtgcc acccagggca aggagccgcc
    21001 gcgcaccgac tgcgtccgcg agcggctgcc ggacggcggc gtcc
//
