LOCUS       NC_015953              21077 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. SirexAA-E, complete sequence.
ACCESSION   NC_015953
VERSION     NC_015953.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Streptomyces sp. SirexAA-E
  ORGANISM  Streptomyces sp. SirexAA-E
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7414440)
  AUTHORS   Takasuka,T.E., Acheson,J.F., Bianchetti,C.M., Prom,B.M.,
            Bergeman,L.F., Book,A.J., Currie,C.R. and Fox,B.G.
  TITLE     Biochemical properties and atomic resolution structure of a
            proteolytically processed beta-mannanase from cellulolytic
            Streptomyces sp. SirexAA-E
  JOURNAL   PLoS One 9 (4), e94166 (2014)
   PUBMED   24710170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Streptomyces sp. SirexAA-E
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2011) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. SirexAA-E
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            environment                       :: Soil, Terrestrial
            num_replicons                     :: 1
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly                          :: Newbler v. 2.3 (pre-release)
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi05895
            Funding Program                   :: DOE-GLBRC 2008
            Source of Isolate :: Cameron Currie (currie@bact.wisc.edu)
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method                   :: Newbler v. 2.3
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000177195.2-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 02:12:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,619
            CDSs (total)                      :: 6,532
            Genes (coding)                    :: 6,385
            CDSs (with protein)               :: 6,385
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 61 of 147
            Pseudo Genes (incomplete)         :: 120 of 147
            Pseudo Genes (internal stop)      :: 8 of 147
            Pseudo Genes (multiple problems)  :: 39 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3098524
            Orig. end                         :: 3119601
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002993.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086644
            Source DNA and organism available from Cameron Currie
            (currie@bact.wisc.edu)
            Contacts: Cameron Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21077
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="12"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21077
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21077
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11077](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11077
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(24..1775)
                     /gene="lysS"
                     /locus_tag="SACTE_RS13660"
                     /old_locus_tag="SACTE_2755"
     CDS             complement(24..1775)
                     /EC_number="6.1.1.6"
                     /GO_component="GO:0017101 - aminoacyl-tRNA synthetase
                     multienzyme complex [Evidence IEA]"
                     /GO_function="GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lysS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380410.1"
                     /locus_tag="SACTE_RS13660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2755"
                     /product="lysine--tRNA ligase"
                     /protein_id="WP_019993463.1"
                     /transl_table=11
                     /translation="MPTVASSQSSTETDWVSRFADDVIAESERRAPGKPVVVASGLSPS
                     GPIHLGNLREVMTPHLVADEIRRRGYTVRHLISWDDYDRYRKVPNGVEGVDDSWQEHIG
                     KPLTSVPAPAGSAYPNWAEHFKAAMTRALDELGVEYDGISQTQQYLAGTYREQILHAMR
                     HRADIDAVLDRYRTKKDGAAGGKKPQQKKVDEAELEAAEGSGAASEDDGSSNAAGYFPY
                     KPYCGNCEKDLTVVTSYDDDSTELNYTCSACGFAETVRLSEFNRGKLVWKVDWPMRWAY
                     EGVIFEPSGVDHSSPGSSFVVGGQIVREVFDGVQPIGPMYAFVGISGMAKMSSSKGGVP
                     TPADALKIMEAPLLRWLYARRKPNQSFKIAFDQEIQRLYDEWDSLARKVADGTVLPADA
                     AAYARAIGTAAGELPSTPRPLPYRTLASVADITAGAEDQTLRILSELDPENPLTSLDEA
                     RPRLDRAESWISTQVPAEARTVVRQEPDKELLGSLDDKGRESLRLLLDGLETHWSLDGL
                     TTLVYGVPKVLEGLEPDARPTPELKVAQRSFFALLYRLLVSRDTGPRLPTLLLAVGADR
                     VRTLLGG"
     gene            1927..3696
                     /gene="argS"
                     /locus_tag="SACTE_RS13665"
                     /old_locus_tag="SACTE_2756"
     CDS             1927..3696
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552223.1"
                     /locus_tag="SACTE_RS13665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2756"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_019993462.1"
                     /transl_table=11
                     /translation="MASVPSLASTLQQQLADALTAALPEAGTADPLLRRSDRADFQANG
                     ILALAKKLKGNPRELAAKVTDTLPSGELIKDIEVSGPGFLNITLTDRAITETLAARAAD
                     GDRLGVPVKADAGTTVIDYAQPNVAKEMHVGHLRSAVIGDAMVQILEFTGETVVRRHHI
                     GDWGTQFGMLIQYLFEHPGELGHEGGEADGEAAMSSLNRVYKASRVLFDSDEEFKARSR
                     DRVVALQAGDPETLALWQGFVDESKIYFYSVFDKLDMEIRDADIVGESGYNDMLEETCR
                     ILEETGVAVRSEGALCVFFDDVKGPDGNPVPLIVKKTNGGYGYAATDLSAIRDRVQGLK
                     ADTLLYVVDARQSLHFKMVFETARRAGWLNEDVTAHQLAFGTVLGKDGKPFKTREGTTV
                     RLEDLLDEAVERATAVVREKAEKVGLSEEEIVENGRYVGVGAVKYADLSTSAVRDYKFD
                     LDQMVSLNGDTSVYLQYAYARIRSILRKAGDANPAAHPELELAPAERALGLHLDQFGAV
                     LSEVAEGYEPHKLAAYLYQLASHLTTFYDQCQVLSDDNPAEVVENRLFLVELTARTLHQ
                     GMRLLGIRTPERL"
     gene            complement(3794..4222)
                     /locus_tag="SACTE_RS13670"
                     /old_locus_tag="SACTE_2757"
     CDS             complement(3794..4222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019767145.1"
                     /locus_tag="SACTE_RS13670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2757"
                     /product="hypothetical protein"
                     /protein_id="WP_014046624.1"
                     /transl_table=11
                     /translation="MSETLDTPAATAAVITEPVPDLQLQLLMRLLDREQRSSLPITLTT
                     SSGILHGDLIGHEAWKADWARALRQVEGEGTNLLAEFPETVDQGLREMVADDDASSLPR
                     WIHLRDATLVMGGAGKVRLPLWRGRLADVSGWALGRPQ"
     misc_feature    complement(4367..4381)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.68"
                     /tool="antismash"
     gene            4385..4672
                     /locus_tag="SACTE_RS13675"
                     /old_locus_tag="SACTE_2758"
     CDS             4385..4672
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046625.1"
                     /locus_tag="SACTE_RS13675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2758"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_014046625.1"
                     /transl_table=11
                     /translation="MSHYNGSPTAASRSGTNGLAVASLVCGIVGLVVFSVILGPVAIVL
                     GVLGLRQVSAKGGTGLAKAGLVLGIIDLVLFLVLMIAATSSGGFSWYVGG"
     gene            complement(4750..5982)
                     /locus_tag="SACTE_RS13680"
                     /old_locus_tag="SACTE_2759"
     CDS             complement(4750..5982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152486.1"
                     /locus_tag="SACTE_RS13680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2759"
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_014046626.1"
                     /transl_table=11
                     /translation="MSSHIDERPVDDEAPGAPDAPEGAVFAERTQRLRRRLERLIGIAA
                     TEGNELVPLRNGDQIFAAMLDAIRSAEHTVDMMTFVYWRGDIARDFAEALSGRARAGVR
                     VRLLLDGFGSRLIEKDQLAMMEAAGVQVAWFRKPLYLSPLKQNHRCHRKVLITDERTAF
                     TGGVGIAEEWCGDARNEHEWRDTHVKVRGPAVDGLAAAFAQNWAECHDELFDAHDRFVA
                     LEPHGDAIVQVVRGSASFGWQDMQTLLRVVLESAEERVRLTTAYFAPDTFFVGLLCAAA
                     RRGVTVEVLLPGPHTDKRVCQLAGQHHYEALTACGVKIYQYQPTMMHTKALTVDRVAAL
                     IGSTNFNRRSLDHDEEVMLAVLDPEFTATLDGHFEEDVTQSELIDGARWRRRSPAQRMR
                     EVAVQPIRRWL"
     gene            complement(6056..7558)
                     /locus_tag="SACTE_RS13685"
                     /old_locus_tag="SACTE_2760"
     CDS             complement(6056..7558)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046627.1"
                     /locus_tag="SACTE_RS13685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2760"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_014046627.1"
                     /transl_table=11
                     /translation="MPFRDAGEGGTVGVGTEIQDFAAELRGLKERSGLSYGALAQKLHM
                     STSTVHRYCNGDAVPHDYAPVERFARVCRASGDELVALHRKWILADEAKRRGARKPEAA
                     AGPGPRAAVERPDGDPAPDPAPGPDPAPGPDAAPGPAPGAAPEPVDAPEPAPRSGTGPE
                     PETEPGPESVAEDVTAAVPTGATAVPAPRPKRFGRSRVLLAAAAVVALTVPGALAVHSL
                     TEGDPADEVRPGTAAESVVVTPDTSDRPGAGASPSPSRTSASPSASATGGATGAASASP
                     SSSAAKGEERKNGGVPVRASITSYNWEEPCGQYYLLDEEPDHVPPPPSPQGTRAWARAL
                     DGVDGEAMRLQLTLQGDSDEAVVLNALHVRVLGRKPALAWSAYSMGDGCGSGIVPQSFD
                     IDLDDNLPRTKPVAGQDGDTVVPAKDFPYRVSSSDVQVFHLDAHVAGHDVTWYLELEWT
                     SGGRSGTLRIDDGGKPFRTSGIAGRPEYRYRYDTAQWVAPDL"
     gene            7900..8655
                     /locus_tag="SACTE_RS13690"
                     /old_locus_tag="SACTE_2762"
     CDS             7900..8655
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046629.1"
                     /locus_tag="SACTE_RS13690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2762"
                     /product="DUF4232 domain-containing protein"
                     /protein_id="WP_014046629.1"
                     /transl_table=11
                     /translation="MRTLHLRRAARTSALSSAALLAALALTACQGGGQTAADASTSAST
                     APSAQPAADAEAPADQDAQASGSDATADSVSSSGGDSGSAAGKSRPGATEVQPAAREKN
                     ESDSGPVTLACDGGNTEVTFRTVTRPVNHGLLTVTNTGSKACNAYGYPAVRFGEAQSVP
                     PVYEESKPQAVVTLAPGESAYAGVTTSAADGSGTGGYSTKSLSVYFQGRDLSGSTGPEA
                     RVPLATKVYVDSKLTVTYWQSDLDNALMY"
     gene            8874..10004
                     /locus_tag="SACTE_RS13695"
                     /old_locus_tag="SACTE_2763"
     CDS             8874..10004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046630.1"
                     /locus_tag="SACTE_RS13695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2763"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_014046630.1"
                     /transl_table=11
                     /translation="MAHVAAAQQEPLREAAQQCKAFAPEYQGALGSLSVNASLTEVRAR
                     GIEELRAAEASGDRREMARCHLAVAEACRRLGHNEEADRAWKAGYRAARSAQDAGAMAW
                     ALWSGGTLARQRGALPLAYRLLRLAADLGERGGDIVVRGYSLAGLAETGRIQGDYKAVG
                     ELHEQLLAEARRRGEARHTVWALEGIAQMHRNTGAYDTALALFEEAAETAGRADDRRGR
                     AWALRGIADVVSVRDQDADRALELLAEAERTCREMRLSSALAYNHKMRGNVLYRAGRYA
                     EAREDYALALSEFRAMDEARGTALARLGLAKSLARLGQDPAETVTELASLRQALGQLGL
                     RHADDMIDRAADELGVGPVPGNGAPAPALAGEGTLR"
     gene            10001..11077
                     /locus_tag="SACTE_RS13700"
                     /old_locus_tag="SACTE_2764"
     CDS             10001..11077
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046631.1"
                     /locus_tag="SACTE_RS13700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2764"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_014046631.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.7e-58, bitscore:
                     196.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSATVTGAAGTRGLLAAPPVLDRCRALVRPALADAVGRLHPWPG
                     EMAAHALGWRDTAGTPDPAASEGKGVRQALAVLGAELCGAPGVSAVPGAVAVELVHAFS
                     LVHDDIMDGDELRRQRPAVWKSYGTGPAVLAGDGLLAAAVQTLAQAPGALGGPAVLRLS
                     GALTSLVRGQADDLLFADRPWTGPEAVRPDAYRSMAEHKTGALLGCAAALGALLGGAPD
                     TTVTALDRAGRHLGVAFQAVDDLLGIWGDPARTGKPVHGDLRQRKKTYPVLAALASDGP
                     TARELAALLDSPCPPDDATVAARAADLVEAAGGRTATLAEAHHHLDAARACLRGTPLAP
                     RAVHEVEELLGYLAHRTV"
     gene            complement(11082..11408)
                     /locus_tag="SACTE_RS35005"
     CDS             complement(11082..11408)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155595.1"
                     /locus_tag="SACTE_RS35005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_226995228.1"
                     /transl_table=11
                     /translation="MAYVPKHAQTDLLSAPVAQDRFGDDEADRGRLGAVQDLDALRASG
                     DASGRTLTVEVHDSGEAVPAVRQPRGESGRGLPLVDAVADRWGVRDRGPGKVVWCSFTK
                     SGRG"
     gene            11301..>11588
                     /locus_tag="SACTE_RS35010"
                     /old_locus_tag="SACTE_2766"
                     /pseudo=""
     CDS             11301..>11588
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="SACTE_RS35010"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2766"
                     /product="Scr1 family TA system antitoxin-like
                     transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHGSEPPTVSFVVSEAILRDRGGEQVRLGMLRHVRQYADVPGVTV
                     QIMPLGRQTHAGLSGPFILLETPEHQRLAYTETQRGSQLISAPDDVSILER"
     gene            11630..11905
                     /locus_tag="SACTE_RS32570"
                     /old_locus_tag="SACTE_2767"
     CDS             11630..11905
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552229.1"
                     /locus_tag="SACTE_RS32570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2767"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_050986364.1"
                     /transl_table=11
                     /translation="MEGATGPASRGATSSSLAWFKSSYSSEQGGACLEVAYAWRKSSYR
                     GSDGGNCLEVAAHPSAVHVRDSRNPTGPALTVAPATWSAFAAHVGA"
     misc_feature    11919..11934
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    11944..11959
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.91"
                     /tool="antismash"
     gene            12009..13289
                     /locus_tag="SACTE_RS13710"
                     /old_locus_tag="SACTE_2768"
     CDS             12009..13289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046633.1"
                     /locus_tag="SACTE_RS13710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2768"
                     /product="choice-of-anchor A family protein"
                     /protein_id="WP_014046633.1"
                     /transl_table=11
                     /translation="MRIPATAAIAALGGALVLGLTAVPAAQAAPATSADCTTDAFGIAG
                     KYGEFVLGDDVHSPDAEGAVAVGGNADFTGGFSVANELSAAEVDALPGRASLVVRGDLV
                     NGGSATVVMKGDAVVGGAVKDRKVELHNGSFSRKADLIDFEAEFAKLRSYSSALAGESA
                     TDGTKVSLDGPKLTLEGSAGDRNVFSVPAEQLEKAKEVFIKVPAGATTVVNVGGQGYDM
                     AAAGTTGFFLSGGQDFVLDDKLQSASEGKVRAKLLWNFPDATKVVKNSQAAWPGSVLAP
                     KAHFELGTAAPVNGSVWVASLHGSGGAETHHFPFTGCLPEVPGTETPSPGETPSEGTGT
                     TPPATTTPSASVSPPSESATPSDEPSEGPSESAAPGTPAPSDSPAPGGDLASTGSSGTI
                     PIVIGGAAVLAAGAGLVVMARRRKSQA"
     gene            13404..14192
                     /locus_tag="SACTE_RS13715"
                     /old_locus_tag="SACTE_2769"
     CDS             13404..14192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046634.1"
                     /locus_tag="SACTE_RS13715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2769"
                     /product="DUF4253 domain-containing protein"
                     /protein_id="WP_014046634.1"
                     /transl_table=11
                     /translation="MATLPNSLPSLATSGLDLPSGTLVDATAGGPWHEPLLWHADEPVR
                     PGAWRDLRTRARGLGLLPVLVDGGRRGLWPAGWELDPARTSYPGDHDAEEVLRGFWEDN
                     ADDELAAPDTAWPGLSPAPRGGTCEDPDVLAGEIADMFAESPDGPRFRMGLVPARRSAD
                     IPASIGWRGPLNHENDVARLCAVLRSWEDRFGIRVLIIGFDTLVVSVGRPPTTLAEARA
                     LAAEHFAFCPDSIDQNPPYGLDLYAERNLLGQATWGFWWD"
     gene            14241..14594
                     /locus_tag="SACTE_RS13720"
                     /old_locus_tag="SACTE_2770"
     CDS             14241..14594
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046635.1"
                     /locus_tag="SACTE_RS13720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2770"
                     /product="hypothetical protein"
                     /protein_id="WP_014046635.1"
                     /transl_table=11
                     /translation="MREEDLLNPRVRHAWVAPLLSTLLTLPAAGFALLYGGLSPMACDS
                     CDGAEADRFTESFDAAWSVLCTGLLLSMAVLLTSWVLPWRLRQAPRRLVLATAAPAVVA
                     VAFVAFTALVDRP"
     gene            complement(14890..15483)
                     /locus_tag="SACTE_RS13725"
                     /old_locus_tag="SACTE_2771"
     CDS             complement(14890..15483)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046636.1"
                     /locus_tag="SACTE_RS13725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2771"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_014046636.1"
                     /transl_table=11
                     /translation="MTVPPVSRRDRKKAATRQAIADAALQLFLERGYDRVGIRDIADAA
                     DVSTATVFKHFSGKEALVFDQDQDRESALIAAVRERPSGQSLLDALRQHVLDTWPTIEA
                     HPQAAEFTHLVNSTPALSAYAERMWTRHTDSLSAAIADEAGVDHDDPSCVALARFVLDV
                     PALARGRQDRRAAIQAIFDILTHGWKPPGTPSRP"
     misc_feature    complement(15439..15448)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            15737..16891
                     /locus_tag="SACTE_RS13730"
                     /old_locus_tag="SACTE_2772"
     CDS             15737..16891
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046637.1"
                     /locus_tag="SACTE_RS13730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2772"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_014046637.1"
                     /transl_table=11
                     /translation="MNSPEPANARISIIGAGPGGLTCARVLQRRGIAVTVYDRDPGPDA
                     RNQGGTLDLHADNGQVALREAGLLDAFFALARPEGQEMRQMDAAGTITSHQIPAPDELF
                     KPEIDRGQLRDLLLESVQPGTVHWGRALDTISGPADGPRRLHFADGTTVETDLVIGADG
                     AFSRVRPAVSPAVPEYTGVSFLEAWFSDVENRHPAIAELVGPGSAHAADGERGLFAQRN
                     GGNHIRVYLVQRVPVDWISADGLTTEDTDGIRAVLRDRYAHWSPRMLQMITENDGPYVD
                     RPILALPVPHTWDHDATVTLLGDAAHLMPPLGVGVNLAMLDACELALALANAPTVDDAV
                     RAYESTMLPRSTETAEALEHGAEHLLSTGIPDFDDDAQPVDSAH"
     gene            17020..17427
                     /locus_tag="SACTE_RS13735"
                     /old_locus_tag="SACTE_2773"
     CDS             17020..17427
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-133). E-value:
                     4.2e-13. Score: 41.9. Matches aSDomain:
                     nrpspksdomains_SACTE_RS13735_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046638.1"
                     /locus_tag="SACTE_RS13735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2773"
                     /product="SRPBCC family protein"
                     /protein_id="WP_014046638.1"
                     /transl_table=11
                     /translation="MKTPGTASLHLSTHIDRTAEEVYAYASDPSHLPEWAAGLAGSVEE
                     TDGRWIADSPMGQVVVAFAPRNDFGVLDHDVTLPSGEKVHNPVRVIADTTGCEVVFTLR
                     RRPEMSDEDFGRDADAVTADLAALKRALEKG"
     aSDomain        17038..17418
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SACTE_RS13735_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.20E-13"
                     /label="SACTE_RS13735_Polyketide_cyc2.1"
                     /locus_tag="SACTE_RS13735"
                     /protein_end="133"
                     /protein_start="6"
                     /score="41.9"
                     /tool="antismash"
                     /translation="ASLHLSTHIDRTAEEVYAYASDPSHLPEWAAGLAGSVEETDGRWI
                     ADSPMGQVVVAFAPRNDFGVLDHDVTLPSGEKVHNPVRVIADTTGCEVVFTLRRRPEMS
                     DEDFGRDADAVTADLAALKRALE"
     gene            complement(17436..18524)
                     /locus_tag="SACTE_RS13740"
                     /old_locus_tag="SACTE_2774"
     CDS             complement(17436..18524)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046639.1"
                     /locus_tag="SACTE_RS13740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2774"
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="WP_014046639.1"
                     /transl_table=11
                     /translation="MKTLDARELNRATLARQLLLDRARLPPLDAVAHLCGLQAQEPQEP
                     FVGLWSRLRGFAPEALDGLLTGRHVVRTHLMRRTVHLVTADDALAWRARHGAMLRQRVL
                     GTYRRELGGVDLDALAAAVRAVMADGEPRTMTEIALHLADRWPAPGRRPLGEMAVAALV
                     PMVQLPPRGTWRVKAGVRNTPLAHWLGREPDPPGRPGADAAGEALVLRYLAAYGPAASA
                     DLRAWCGLAGLPAAVAAVRDRLVAFRDERGRELLDLPDAPRPDPGTPAPVRFLPAFDNA
                     ILGYQDRSRIIDDAHRGLSVQGARVVLVDGRVAASWTVDAGTVDVSPLRGLGRAERAAV
                     LEEGGHLALFLSDGDSDRVRVG"
     gene            complement(18521..18943)
                     /locus_tag="SACTE_RS13745"
                     /old_locus_tag="SACTE_2775"
     CDS             complement(18521..18943)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046640.1"
                     /locus_tag="SACTE_RS13745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2775"
                     /product="VOC family protein"
                     /protein_id="WP_014046640.1"
                     /transl_table=11
                     /translation="MSVTSVTHLNFRGEARAALDFYRSVFGGDLAIVSYQDAGAVDDPA
                     EADQVMWGQVTAENGFRVMAYDVPSRLPWDRGENSFFVSVRGDDAAEVTEYWEKLSAGA
                     DVVQPLGPARWAPLYGMLRDRYGVVWVVDVVSGYGG"
     gene            19061..20044
                     /locus_tag="SACTE_RS13750"
                     /old_locus_tag="SACTE_2776"
     CDS             19061..20044
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181314.1"
                     /locus_tag="SACTE_RS13750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2776"
                     /product="YafY family protein"
                     /protein_id="WP_019993458.1"
                     /transl_table=11
                     /translation="MPKTSARLLALLSLLQARRDWPGALLAERLDISPRTVRRDVDRLR
                     ELGYPIAAFKGPEGGYRLQAGTELPPLLFDDEQAVALTLALQVVTATGAGVEEAAARAL
                     TTLRQVMPARLRHRVDALQVTAVDPAPTGGRPQAGGGTLMALSSAVHAREVLRFDYTAG
                     TGAPRRAEPHHLVTYAGRWYLVAWDLDREDWRTFRADRISPRVPTGPRFAPREVPGGDV
                     AAFVAGRFRGADAHGDWPCHGEVVLRTAAATVAPYVRDGLVEALGPDRCRLVLGAWSWT
                     ALAATLGRFDADIEAVGPDELRRAFARLARRYADAATDHRPPPPGP"
ORIGIN
        1 ccggttcttc gtacacggcg gtgtcagccg cccagcagcg tccgcacccg gtccgccccc
       61 accgcgagca gcagcgtggg cagccgcggg ccggtgtccc ggctgaccag cagccggtac
      121 agcagcgcga agaaggaccg ctgggccacc ttgagctccg gcgtgggcct ggcgtccggc
      181 tccaggccct ccagcacctt cggcacgccg tagacgagcg tggtcagccc gtccagcgac
      241 cagtgcgtct ccagcccgtc cagcagcagc cgcagcgact cgcggccctt gtcgtccagg
      301 gatccgagca gttccttgtc cggctcctgg cgcacgacgg tgcgggcctc ggccgggacc
      361 tgggtgctga tccagctctc cgcccggtcc agccggggac gcgcctcgtc gagcgaggtc
      421 agcgggttct ccgggtccag ctcgctgagg atgcgcagcg tctggtcctc ggcaccggcc
      481 gtgatgtccg cgaccgaggc gagcgtgcgg tacggcagcg ggcgcggggt gctgggcagc
      541 tccccggcgg ccgtgccgat cgcacgggcg taggcggcgg cgtccgcggg cagcaccgtg
      601 ccgtcggcga ccttgcgggc gagcgagtcc cactcgtcgt agagccgctg gatctcctgg
      661 tcgaacgcga tcttgaacga ctggttgggc ttgcggcgcg cgtacagcca gcgcagcagc
      721 ggcgcctcca taatcttcag cgcgtcggcc ggggtcggca cgccgccctt gctggaggac
      781 atcttggcca tgccggagat cccgacgaac gcgtacatcg ggccgatcgg ctggaccccg
      841 tcgaagacct cgcggacgat ctgcccgccg acgacgaacg aggagccggg cgaggagtgg
      901 tccacaccgc tgggctcgaa gatcacgccc tcgtaggccc agcgcatcgg ccagtcgacc
      961 ttccagacca gcttgccgcg gttgaactcg ctcagccgga ccgtctcggc gaagccgcag
     1021 gccgaacagg tgtagttcag ctcggtggag tcgtcgtcgt aggaggtgac gacggtgagg
     1081 tccttctcgc agttgccgca gtacggcttg tacgggaagt agccggccgc gttcgagctg
     1141 ccgtcgtcct cgctcgccgc gccggagccc tcggcggcct ccagctcggc ctcgtccacc
     1201 ttcttctgct gcggcttctt cccgcccgcc gcgccgtcct tcttggtgcg gtagcggtcc
     1261 aggacggcgt cgatgtcggc gcggtgcctc atggcgtgca ggatctgctc gcggtaggtg
     1321 cccgcgaggt actgctgggt ctggctgatg ccgtcgtact cgacgccgag ctcgtccagg
     1381 gcccgggtca tggcggcctt gaagtgctcg gcccagttcg ggtacgcgga gccggccggg
     1441 gcgggcaccg aggtcagcgg cttgccgatg tgctcctgcc aggagtcgtc gacgccctcg
     1501 accccgttcg gcaccttgcg gtagcggtcg tagtcgtccc acgagatcag gtggcgcacg
     1561 gtgtacccgc ggcggcggat ctcgtcggcg accaggtgcg gggtcatgac ctcgcggagg
     1621 ttgccgaggt ggatcgggcc cgacggggag aggccggagg cgacgacgac cggtttgcca
     1681 ggcgcacgtc gctccgattc ggcgatgaca tcgtccgcga agcgggagac ccagtcggtc
     1741 tcggtgctgc tctgactcga agccacggtc ggcacgtcct tctctcgtgt aggactcaat
     1801 cgggggaccc cgctctcagg gggtgcctcc attctcccag gtgccacccg tagcgcgaaa
     1861 acggctttac accccgtggg atactgggac ggatcccttg tcctctaccg aaacggcagc
     1921 cggctcatgg cctcggtccc ttccctcgct tccacgctcc agcagcagct ggcggacgcc
     1981 ctgacggcag cactgcccga ggccggcacc gcggacccgc tgctgcgccg aagcgaccgg
     2041 gccgacttcc aggccaacgg catcctcgcg ctcgccaaga agctcaaggg caacccgcgt
     2101 gagctggccg cgaaggtcac ggacaccctc ccgtcgggtg agctgatcaa ggacatcgag
     2161 gtctccggcc ccggcttcct caacatcacg ctcaccgacc gggcgatcac cgagacgctc
     2221 gccgcgcgcg ccgccgacgg cgaccggctc ggcgtcccgg tgaaggccga cgcgggcacc
     2281 accgtgatcg actacgccca gcccaacgtg gccaaggaga tgcacgtcgg ccacctgcgg
     2341 tccgcggtca tcggcgacgc gatggtccag atcctggagt tcaccggcga gaccgtcgtc
     2401 cggcgccacc acatcggcga ctggggcacc cagttcggca tgctcatcca gtacctcttc
     2461 gagcacccgg gcgagctggg ccacgagggc ggcgaggcgg acggcgaggc ggcgatgtcc
     2521 tccctgaacc gcgtctacaa ggcgtcccgg gtcctcttcg actccgacga ggagttcaag
     2581 gcgcgctccc gggaccgggt ggtggcgctc caggccggcg acccggagac gctggcgctc
     2641 tggcagggct tcgtcgacga gtcgaagatc tacttctact cggtcttcga caagctcgac
     2701 atggagatcc gcgacgccga catcgtcggc gagtcgggct acaacgacat gctcgaggag
     2761 acctgccgga tcctggagga gacgggcgtc gccgtccgct ccgagggcgc gctgtgcgtc
     2821 ttcttcgacg acgtgaaggg cccggacggc aacccggtcc cgctgatcgt caagaagacg
     2881 aacggcggct acggctacgc ggcgaccgac ctctccgcga tccgcgaccg cgtgcagggc
     2941 ctcaaggccg acaccctgct ctacgtcgtg gacgcccggc agtccctgca cttcaagatg
     3001 gtcttcgaga cggcccgccg cgccggctgg ctgaacgagg acgtcacggc gcaccagctg
     3061 gccttcggca cggtcctggg caaggacggc aagccgttca agacccgtga gggcaccacc
     3121 gtccggctgg aggacctgct ggacgaggcc gtcgagcggg ccaccgcggt ggtccgggag
     3181 aaggccgaga aggtgggcct gtccgaggag gagatcgtcg agaacggccg gtacgtcggc
     3241 gtgggcgccg tgaagtacgc ggacctgtcg acctccgcgg tgcgggacta caagttcgac
     3301 ctggaccaga tggtgtcgct caacggcgac acctcggtgt acctccagta cgcctacgcc
     3361 cggatccgct ccatcctgcg caaggcgggg gacgcgaatc ccgccgcgca cccggagctg
     3421 gagctggccc cggccgagcg cgcgctcggc ctccacctgg accagttcgg cgcggtcctg
     3481 tccgaggtcg ccgaggggta cgagccgcac aagctggccg cgtacctcta ccagctggcc
     3541 tcgcacctga ccacgttcta cgaccagtgc caggtgctga gcgacgacaa cccggcggag
     3601 gtcgtcgaga accggctctt cctggtcgag ctcaccgccc gcaccctgca ccagggcatg
     3661 cggctcctcg gcatcaggac gcctgagcgc ctgtgacgcc ccgaccacgt cccgaggccc
     3721 ccggctgcca ccgcgccggg ggcctcggcc gtcgtccggg gccgcaccgg gggcctccgc
     3781 cgtcgtccgg ggcctactgc ggccggccca gtgcccaccc cgacacgtcc gccagccgac
     3841 cgcgccacag gggcagccgt accttgcccg cgccgcccat caccagcgtg gcgtcccgta
     3901 gatggatcca gcggggcagc gaggacgcgt cgtcgtccgc caccatctcc ctgaggccct
     3961 ggtccaccgt ctcggggaac tccgccagca ggttggtgcc ttcgccctcg acctgccgca
     4021 gggctctcgc ccagtccgcc ttccacgcct cgtgaccgat caaatccccg tggaggatgc
     4081 cggaggacgt ggtcagggtg atgggcaggc tggagcgctg ctctctgtcc agcagtctca
     4141 tcagcagctg gagttgcagg tcgggcacgg gctccgtgat caccgcggcg gtcgccgccg
     4201 gtgtatcgag ggtctcactc atgggccact tcccttcacc tgacgcgtgg caggtgcagg
     4261 cccgtgtgcc cccggccggg gccctcacac ccccgtcgtc cgagtggttg tgggcgcgga
     4321 agccgggcac tcgccctgta cctgcaactc cacgtacagc acggcgaatt gacgggagaa
     4381 agtgatgtcg cactacaacg gttcacccac ggccgcgtcc cggtcgggga ccaacggtct
     4441 cgccgtcgcg agcctggtct gcgggatcgt ggggctcgtc gtgttcagcg tgatcctggg
     4501 ccccgtcgcc atcgtcctcg gtgtcctcgg cctgcgccag gtgtccgcga agggcggcac
     4561 cgggctggcc aaggccggtc tggtcctcgg catcatcgac ctcgtgctct tcctggtcct
     4621 gatgatcgcg gccacctcgt ccggcggctt cagctggtac gtcggcggct gacacgtccg
     4681 tacgacgtcg cgggggcggt cccaccgaac cggtgggacc gcccccgtcg tgccgtcacc
     4741 gaccgcccgt cacagccagc ggcggatcgg ctggaccgcg acctcgcgca tccgctgtgc
     4801 cggcgagcgg cgccgccagc gggcgccgtc gatcagctcg ctttgggtca cgtcctcttc
     4861 gaagtgcccg tccagcgtcg cggtgaactc cgggtccagc acggcgagca tcacctcctc
     4921 gtcgtggtcg agggagcggc ggttgaagtt ggtggagccg atcagcgcgg cgacccggtc
     4981 caccgtcagc gccttggtgt gcatcatcgt cggctggtac tggtagatct tcacgccgca
     5041 ggcggtgagg gcctcgtagt ggtgctggcc cgcgagctgg cagacccgct tgtcggtgtg
     5101 cggccccggg agcaggacct ccacggtcac cccgcgccgg gcggcggcgc acagcagccc
     5161 cacgaagaag gtgtcgggcg cgaagtacgc cgtggtcagc cggacccgct cctcggcgga
     5221 ctccaggacg acccgcagca gggtctgcat gtcctgccag ccgaagctgg ccgagccacg
     5281 caccacctgc acgatcgcgt cgccgtgcgg ttcgagcgcg acgaaccggt cgtgcgcgtc
     5341 gaagagctcg tcgtggcact cggcccagtt ctgggcgaac gcggcggcga gaccgtccac
     5401 ggccgggcct cgcaccttca catgggtgtc acgccactcg tgttcgttgc gggcgtcgcc
     5461 gcaccattcc tcggcgatgc cgacgccgcc ggtgaacgcc gtccgctcgt cggtgatgag
     5521 gaccttgcgg tggcagcggt ggttctgttt gagcggcgac aggtacagcg gcttgcggaa
     5581 ccaggccacc tgcaccccgg ccgcctccat catcgccagc tggtccttct cgatcagccg
     5641 gctgccgaag ccgtccagca gcaaccgcac ccggaccccc gcacgggccc gcccggacag
     5701 cgcctcggcg aagtcgcggg ctatgtcgcc gcgccagtac acgaaggtca tcatgtccac
     5761 ggtgtgctcc gcggaccgga tggcgtccag catcgcggcg aagatctggt ccccgttgcg
     5821 gagcggtacc agttcgttcc cctcggtcgc ggcgatcccg atgaggcgtt cgagccgccg
     5881 tcgcaggcgc tgggtgcgtt ccgcgaagac ggcaccctcc ggcgcgtccg gcgcgccggg
     5941 tgcctcgtcg tccacgggtc tctcgtctat gtggctggac atcttctccc tgctcatgcc
     6001 gatggggacg ggctcgcgac tgtactcctg gccgtccccg tccccgggta cccgctcaga
     6061 ggtccggtgc cacccactga gcggtgtcgt agcggtaccg gtactcgggc cggcccgcga
     6121 taccgctcgt acggaacggc ttgccgccgt cgtcgatgcg cagggtgccg ctccggcccc
     6181 cgctggtcca ctccagctcc aggtaccagg tcacgtcgtg ccccgccacg tgcgcgtcca
     6241 ggtggaacac ctgcacgtcg ctggagctga cccggtacgg gaagtccttc gcgggcacga
     6301 ccgtgtcacc gtcctgcccc gccaccggct tcgtacgggg caggttgtcg tccaggtcga
     6361 tgtcgaagct ctgcgggacg atgccgctcc cgcagccgtc gcccatcgag tacgcggacc
     6421 aggcgagcgc cggcttccgc cccagcaccc gcacgtgcag cgcgttcagc acgaccgctt
     6481 cgtccgaatc gccctggagg gtgagctgga gcctcatggc ttccccgtcc accccgtcga
     6541 gggctcgcgc ccaggcacgg gtgccctgag gcgaaggcgg cggcgggacg tggtcgggct
     6601 cctcgtcgag caggtagtac tgcccgcagg gctcctccca gttgtacgaa gtgatggagg
     6661 cccgcacggg caccccgccg ttcttccgct cctcgccctt cgcggcggac gaggacggcg
     6721 aggcggaagc agcgcccgtg gccccgcccg tcgcggaggc ggagggcgag gcggacgtcc
     6781 gggagggtga cggggaggcg ccggcgccgg gcctgtcgct cgtgtccggt gtgacgacca
     6841 cgctttcggc ggccgtaccg ggacgcacct cgtcggccgg atcaccctcg gtgaggctgt
     6901 gtacggccag cgcgcccggc acggtgagcg ccacgacggc cgccgccgcg agcaggaccc
     6961 gggatcgccc gaaccgcttg ggccggggtg cggggacggc cgtcgcaccg gtgggcaccg
     7021 cggccgtcac gtcctccgcg acggattccg gtccgggttc cgtttccggt tccggaccgg
     7081 tgcccgaccg gggtgcgggc tccggtgcgt ccaccggctc aggcgccgcc ccgggggccg
     7141 ggccgggagc cgcgtccggg ccgggcgcgg ggtccggacc gggcgcgggg tccggcgccg
     7201 ggtccccgtc cgggcgctcc acggccgccc gcgggcccgg cccggcagcc gcctccggct
     7261 tccgcgcgcc tcggcgcttc gcctcgtcgg cgaggatcca cttccggtgc agggccacca
     7321 gctcgtcgcc cgaggcacgg cacacccggg cgaaccgttc caccggggcg tagtcatgcg
     7381 gtacggcgtc gccgttgcag taccggtgga ccgtcgacgt gctcatgtgg agcttctggg
     7441 cgagcgcccc gtaactcagc ccggaccgct ccttgagccc cctgagctct gccgcgaagt
     7501 cctggatctc cgtacccacc ccgaccgtcc ctccctctcc cgcgtcccgg aacggcattc
     7561 cagggcgaca ccgtttccgc aggtcagcat gtgttccagc gttcctgtgt cccgcacggt
     7621 ccggcaaccg ttgccaccgg gacacgacgc cgcacaggat gtggacacac caccgagacc
     7681 acctcgcccc acccgggaga cgccgtgcgt acccgactcg gaccgatctt gacggacgcg
     7741 atcgccaccg gggtgctgat cgcctccacg gccaccgtcc tcacactcct gtggcgcctc
     7801 tgaccacgcg ccaccaccca gtacatccgg catcaccccg gggcgccaaa cggcgccccg
     7861 ggacagcacg aacaccaact gaacggggag aaccacctca tgcgcaccct tcacctccgc
     7921 cgcgccgccc gcaccagtgc cctcagctcc gccgccctgc tggccgcgct cgccctgacc
     7981 gcctgccagg gaggcggcca gacggctgcc gacgcctcca cctcggcctc caccgccccg
     8041 tccgcccagc cggccgccga cgccgaggcg cccgccgacc aggacgccca ggcatcgggt
     8101 tccgacgcga cggcggattc cgtttcgtcc tccggcggag attccggttc ggccgccggg
     8161 aagagccgtc ccggggcgac cgaggtccag cccgccgccc gggagaagaa cgagagcgac
     8221 agcggccccg tgaccctcgc ctgcgacggc gggaacaccg aggtgacgtt caggaccgtg
     8281 acccggcccg tcaaccacgg actgctcacc gtcaccaaca ccgggtcgaa ggcctgcaac
     8341 gcgtacggct accccgccgt gcgcttcggt gaggcgcagt ccgtcccccc ggtctacgag
     8401 gagagcaagc cgcaggccgt cgtcaccctc gccccgggcg agtccgcgta cgccggcgtc
     8461 acgacctccg ccgccgacgg gagcggcacg ggcggctact ccaccaagag cctgagcgtc
     8521 tacttccagg gccgcgacct ctccggctcc acgggcccgg aggcccgcgt gccgctcgca
     8581 acgaaggtgt acgtcgacag caagctgacc gtgacctact ggcagagcga cctcgacaac
     8641 gccctcatgt actgagcccg acaccccgtc agttcccttc cggggcccgg tccgcgagcg
     8701 cgcgggccgg gccccggccc gggttccccg tacacccgac tgacgacacg gcggcccgtt
     8761 ccgtagccct tgggacggac cgacgaccag cacacagacg gattcgcccg gaccccgccg
     8821 cctcgtacgt tcgtgagcga ccgatacgac cgcacgacgc gcgcaacggt gggatggcac
     8881 acgtggcagc agcacagcag gaaccgctcc gggaagccgc acagcagtgc aaggcgttcg
     8941 ccccggagta ccagggggcc ctgggatcac tttcggtgaa cgcgtcgctc accgaggtgc
     9001 gggcccgggg gatcgaggaa ctgcgggcgg cggaggcgtc cggcgaccgc cgggagatgg
     9061 cccggtgcca cctggccgtc gcggaggcct gccgccggct ggggcacaac gaggaggccg
     9121 accgggcctg gaaggccggc taccgtgccg cccggtccgc gcaggacgcc ggggcgatgg
     9181 cctgggcact gtggagcggt ggcacgctcg cccgccagcg cggcgcactg cccctggcct
     9241 accggctgct gaggctggcc gccgacctgg gcgagcgcgg cggcgacatc gtcgtacgcg
     9301 gctactcgct cgccggtctc gccgagaccg gacggatcca gggggactac aaggccgtcg
     9361 gcgaactgca cgaacaactg ctcgcggagg cccgcaggcg cggcgaggcc cggcacacgg
     9421 tgtgggcgct ggagggcatc gcgcagatgc accgcaacac cggcgcgtac gacacggccc
     9481 tcgccctctt cgaggaggcg gcggagacgg ccggccgcgc ggacgaccgg cggggccgcg
     9541 cctgggcgct gcgcgggatc gccgacgtgg tgtccgtacg tgaccaggac gcggaccgcg
     9601 ccctggaact gctcgccgag gccgaacgca cctgccggga gatgcggttg tccagcgcgc
     9661 tggcgtacaa ccacaagatg cgcggcaacg tgctctaccg ggccggacgg tacgccgagg
     9721 cccgcgagga ctacgccctg gcgctgtcgg agttccgcgc gatggacgag gctcgcggca
     9781 ccgcgctggc ccggctcggg ctcgccaagt cgctcgccag gctcggccag gacccggccg
     9841 agacggtcac cgagctcgcc tcgctgcgcc aggcgctggg gcagctcgga ctgcggcacg
     9901 cggacgacat gatcgaccgg gcggccgacg aactcggcgt gggcccggta cccgggaacg
     9961 gcgccccggc accggccctg gccggcgagg ggacgctgcg atgacctccg ccaccgtcac
    10021 cggcgcggcc ggcacacgcg ggctcctggc cgcgccaccg gtcctggacc gctgccgcgc
    10081 cctggtgcgg cccgctctcg ccgacgcggt cggccggctc cacccgtggc ccggcgagat
    10141 ggccgcccac gcgctcggct ggcgtgacac ggcggggacg cccgaccccg ccgcgtccga
    10201 gggcaagggc gtacgccagg ccctcgccgt gctgggggcc gagctgtgcg gagcgcccgg
    10261 ggtgagcgcg gttcccggcg cggtcgccgt cgagctggtc cacgccttct cgctggtgca
    10321 cgacgacatc atggacggcg acgaactgcg gcggcagcgc ccggcggtgt ggaagagcta
    10381 cggcaccggg cccgccgtcc tcgccgggga cgggctgctg gccgccgccg tgcagaccct
    10441 cgcccaggcg cccggcgccc tcggcggccc cgccgtcctc cggctgtccg gggcgctgac
    10501 ctccctggtc cgagggcagg ccgacgacct gctcttcgcg gaccgcccct ggacggggcc
    10561 cgaggccgtg cggcccgacg cctaccggtc catggccgag cacaagaccg gggcgctcct
    10621 gggctgcgcc gccgcgctcg gcgccctgct cggcggggcg cccgacacga cggtcacggc
    10681 cctggaccgg gccggacgcc acctcggcgt ggccttccag gccgtcgacg acctgctggg
    10741 catatggggc gacccggcca ggaccggaaa gccggtccac ggggacctgc ggcagcggaa
    10801 gaagacgtac ccggtgctcg ccgccctcgc atccgacggg ccgacggcac gtgaactcgc
    10861 cgccctgctg gactccccgt gcccgccgga cgacgccacg gtggcggccc gcgcggccga
    10921 cctcgtcgag gcggccggag ggcgcacggc gaccctggcc gaggcccacc accatctcga
    10981 cgccgcccgc gcctgcctgc gcggcacacc gctcgctccg cgtgcggtgc acgaggtcga
    11041 ggagctgctg ggctacctgg cccaccgcac ggtgtgaggc gtcagccccg gccagacttc
    11101 gtgaaggagc accacacgac cttgccgggg ccccggtccc gtacgcccca ccggtcggcc
    11161 accgcgtcca ccagcggcag cccccggccc gactccccgc ggggctgccg cacggcgggg
    11221 acagcctccc cgctgtcgtg cacctcgacc gtcaacgtcc gtcccgacgc gtcgccactc
    11281 gcacggagcg catcgagatc ctgcacggct ccgagccgcc cacggtcagc ttcgtcgtct
    11341 ccgaagcgat cctgcgcgac cggggcggag agcaggtccg tctgggcatg cttcggcacg
    11401 tacgccagta cgccgacgtc cccggcgtca ccgtgcagat catgccgctc ggccgacaga
    11461 cgcacgccgg cctgtccggc cctttcatcc tgctcgaaac gcccgaacac cagcgtctcg
    11521 cctacacgga gacgcagcga ggcagccagc tgatctcggc cccggacgac gtcagcatcc
    11581 tggaacgcaa gtacgcgatg ctgcgaacgc aggccctcga taccgaggaa tcgaaggggc
    11641 tactggaccg gcttccaggg gagcaacgag cagctcactc gcgtggttca agtcgagcta
    11701 cagcagcgaa caaggcggcg cctgcctcga agtggcgtac gcctggcgca agtccagcta
    11761 ccgcggcagc gatggcggca actgcctcga agtcgccgcg cacccctccg ccgtgcacgt
    11821 gcgggactcc aggaacccca cgggccccgc cctcaccgtc gcccccgcca cgtggtccgc
    11881 gttcgccgcg cacgtcggcg cctgaggcac ctgcgcgcat tggtcttgac caatattcgg
    11941 atctatgaga atcatgaccg gagtcgccac aggatcttca taactgcccc gcaggagaac
    12001 cacgcaccat gcgcataccc gcaactgccg ccatcgcggc gctcggcggt gccctcgtac
    12061 tcgggctcac cgctgtcccg gccgcccagg ccgcccccgc cacgtcggcg gactgcacca
    12121 ccgacgcctt cgggatcgcc ggtaagtacg gcgagttcgt cctcggggac gacgtccact
    12181 cccccgatgc cgagggcgcc gtggcggtcg gtggcaacgc cgacttcacg ggcgggttca
    12241 gcgtcgccaa cgagctgtcg gccgccgagg tcgacgccct gcccggccgg gcgtcactgg
    12301 tcgtccgggg cgacctggtc aacggcggct cggccacggt cgtgatgaag ggcgacgcgg
    12361 tcgtcggcgg cgcggtcaag gaccgcaagg tcgagctgca caacggctcg ttcagccgga
    12421 aggccgacct catcgacttc gaggcggagt tcgcgaagct ccgctcctac tcctcggcgc
    12481 tggccgggga atccgcgacg gacggcacca aggtcagcct ggacggcccg aagctgacgc
    12541 tggagggctc cgccggcgac cgtaacgtct tctcggtgcc ggcggagcag ctggagaagg
    12601 ccaaggaggt cttcatcaag gtcccggcgg gcgcgacgac ggtcgtcaac gtcggcgggc
    12661 aggggtacga catggcggcg gccggtacga ccggcttctt cctgtcgggc ggccaggact
    12721 tcgtgctgga cgacaagctc cagagcgcgt ccgagggcaa ggtccgggcg aagctgctgt
    12781 ggaacttccc ggacgccacc aaggtcgtca agaacagcca ggccgcctgg ccgggcagcg
    12841 tgctggcgcc gaaggcccac ttcgagctgg gtacggccgc gccggtcaac ggctcggtgt
    12901 gggtggcctc gctgcacggt tcgggcggtg ccgagacgca ccacttcccg ttcacgggct
    12961 gcctccctga ggtcccgggc acagagactc cgtcgcccgg cgagaccccg agcgagggca
    13021 cggggacgac gcccccggcg acgaccaccc cgtccgcctc ggtgagcccg ccgtccgaga
    13081 gcgccacccc gagcgacgag ccgtccgagg gcccgtccga gtcggccgcg ccgggcaccc
    13141 cggccccgtc ggacagcccg gcccccggtg gggacctggc gtcgaccggt agcagcggca
    13201 cgatcccgat cgtcatcggc ggtgccgcgg tcctcgctgc gggcgccggc ctggtcgtga
    13261 tggcccgccg ccgtaagagc caggcctgag acaccgtgtg atccgggggg cggcgcgaga
    13321 ggttcgcgcc gcccctccac gtctgccggt ccgcgcgttt gggcggcccc gcgctgtcgg
    13381 tggcggctcg taggctcacc accatggcga cgcttccgaa ctccctcccg tcccttgcca
    13441 cgtcggggct ggacctcccg tccggcaccc tggtggatgc cacggcaggc ggcccctggc
    13501 acgagccgct gctctggcac gccgacgaac ccgtgcgccc gggagcctgg cgggaccttc
    13561 gcacccgcgc ccgtggcctg ggcctgctcc ccgtcctcgt cgacggcggg cggcgcggcc
    13621 tctggcccgc aggctgggag ctcgaccccg cgaggacgtc ctaccccggc gaccacgacg
    13681 ccgaagaggt gctccgcggc ttctgggagg acaacgccga cgacgagctc gcggcgccgg
    13741 acaccgcgtg gcccggcctg tccccggcgc cccggggcgg cacctgcgaa gacccggacg
    13801 tcctggcggg cgagatcgcg gacatgttcg ccgagagccc cgacgggccc cggttccgca
    13861 tggggctggt ccccgcgcgg cggagcgccg acataccggc ctcgatcggc tggcggggcc
    13921 cgctgaacca cgagaacgac gtggcgcggc tgtgtgccgt gctgcgctcg tgggaggacc
    13981 gcttcggcat ccgcgtcctg atcatcggct tcgacaccct ggtcgtctcg gtggggcgtc
    14041 cgcccaccac actcgccgag gcccgggcgc tcgccgcgga gcacttcgcc ttctgcccgg
    14101 acagcatcga ccagaacccg ccgtacggcc tggacctgta tgccgagcgg aacctcctgg
    14161 gccaggcgac ctggggcttc tggtgggact gagtacccgc gctcatgtgc cgggccgccg
    14221 ggcggcgttg actcgtacgc atgcgagaag aagacctgct gaacccgcgc gtccggcacg
    14281 cctgggtggc accgctgctc tccacgctgc tcaccctgcc ggcggcgggc ttcgccctgc
    14341 tctacggcgg cctgtcgccg atggcctgcg actcctgtga cggcgcggag gccgaccgct
    14401 tcaccgagtc gttcgacgcg gcctggtccg tgctgtgcac cggactcctg ctgtcgatgg
    14461 ccgtgctgct gacgagctgg gtgctgccct ggcgcctccg gcaggcaccc cggcgcctcg
    14521 tcctcgcgac ggccgcgccc gccgtcgtcg ccgtcgcgtt cgtcgccttc acggccctcg
    14581 tcgaccggcc gtagtgtcga ccggtcctca cgcggtggcc gtcgcgggcc gcgccgtcgt
    14641 acgtggggaa ggggacgggg cggtgtacca ggtccgcccg cccggagttc tgtcggaaag
    14701 gggggcctcc ctcaccgcct cccccggcgc gtgcacgcac tgcacgcccg gcgccgggcg
    14761 gggacgcgcc gtctcgatgg gctggaccgc tgccgcaacc gtgccgacga cgagcaggcg
    14821 tcggcagcgc cgatagcctc cgggggacgt cacgtccctt tccgtggccg ggccgaggcc
    14881 gatgaggggc tacggccgag acggcgtgcc gggcggtttc cagccgtgcg tgaggatgtc
    14941 gaagatcgcc tggatggcgg cccggcggtc ctgccggccg cgggcgaggg ccgggacgtc
    15001 gaggacgaac cgcgcaagag ccacgcatga cgggtcgtcg tggtccacgc cggcctcgtc
    15061 ggcgatggcc gcgctgaggc tgtcggtgtg cctggtccac atgcgttcgg cgtacgcgct
    15121 cagcgcaggc gtggagttca ccaggtgggt gaactcggcc gcctggggat gcgcctcgat
    15181 cgtgggccag gtgtcgagga cgtgctgccg gagggcgtcg aggaggctct ggccggaggg
    15241 ccgctcccgc accgcggcga tcagcgccga ctcccggtcc tggtcctggt cgaacaccag
    15301 cgcttcctta ccgctgaagt gcttgaacac cgtggcggtg gacacgtcgg cggcgtcggc
    15361 gatgtcacgg atacctacgc gatcgtagcc acgctccaga aagagctgca gtgcggcgtc
    15421 ggcgatcgcc tgccgggtgg ccgccttctt gcggtcgcgg cggctgacgg ggggcacggt
    15481 catgacgaga gcgtatccga tagtcgaatc catcgctaag tagaaccgtt gcacttttcg
    15541 tgttgttctg ttttcatgaa gctgtgaacg cctgagcggc acgcctcgcc ggcctggtca
    15601 ccgtccgcac cgcacctccc gtcgtcgtcc tgtccgtcaa ggggacgctc gaccgaggca
    15661 gctccctcac cgaggccgga gtgccacgcc ccgctctgtt ccgacgactc ctcttcgccg
    15721 accggaagga acgaccatga actccccaga gcccgccaac gcccgcatca gcatcatcgg
    15781 cgccggaccg ggcggactga cctgcgcccg cgtcctccag cgacgtggca tcgcggtcac
    15841 cgtctacgac cgcgacccgg gccccgacgc ccgcaaccag ggcggcaccc tcgacctgca
    15901 cgcggacaac ggccaggtcg ccctgcgcga agccggcctg ctcgacgcgt tcttcgccct
    15961 cgcccgtccc gaagggcagg aaatgcgcca gatggatgcg gccggcacga tcacgtccca
    16021 tcagatcccg gcgccggacg aactcttcaa gccggaaatc gaccgcggcc aactgcgcga
    16081 cctgctgctc gaatccgtgc agccgggaac cgtgcactgg ggccgcgccc tcgacacgat
    16141 cagcggaccc gccgacgggc cgcggcgtct gcacttcgcc gacggcacga ccgtcgagac
    16201 cgatctggtc atcggtgccg acggcgcctt ctcccgggtc cgcccggccg tgtcccccgc
    16261 cgtccccgag tacaccgggg tgagcttcct ggaagcgtgg ttctccgacg tcgagaaccg
    16321 gcaccccgcg atcgccgagc tggtcggtcc gggcagcgcc cacgcagctg acggcgaacg
    16381 cggcctcttc gcccagcgca acggcgggaa ccacatccgc gtctacctcg tccaacgcgt
    16441 cccggtcgac tggatcagcg ccgacggact gaccaccgag gacaccgacg gcatccgcgc
    16501 cgtactacgc gaccggtacg cccactggtc accccgcatg ctccagatga tcaccgagaa
    16561 cgacgggcct tacgtcgacc gcccgatcct cgccctcccc gtcccgcaca cctgggacca
    16621 cgacgcgacg gtgaccctgc tcggcgacgc cgcccacctc atgcctccgc tcggcgtcgg
    16681 cgtcaacctc gccatgctcg acgcctgcga actcgccctc gccctcgcga acgcccccac
    16741 cgtcgacgac gccgtccgcg cctacgagag caccatgctc ccccgctcca ccgagaccgc
    16801 cgaagccctc gaacacggcg ccgaacacct gctctccacc ggcatacccg acttcgacga
    16861 cgacgcccag ccggtggaca gcgcccactg acctcccgcc cttcccgagc ggcgaacacc
    16921 ccgttccgct cccaggccct ggcgaggccg gcccgccggg tacggccgtg accgtttcgt
    16981 acaagagccc gcccggcccg tcccgatagc gtcgcggcca tgaagacgcc cggcaccgct
    17041 tccctgcacc tcagcaccca catcgaccgt acggccgaag aggtctacgc ctacgcctcg
    17101 gacccgtccc acctgcccga gtgggccgcg ggcctggcgg gctccgtcga ggagaccgac
    17161 gggcggtgga tcgcggactc accgatggga caggtcgtgg tcgccttcgc ccccaggaac
    17221 gacttcggcg tactcgatca cgacgtcacg ctgccctccg gggagaaggt ccacaacccg
    17281 gtgcgggtca tcgccgacac caccggctgc gaggtggtgt tcaccctgcg ccgtcggccg
    17341 gagatgagcg acgaggactt cggccgggac gccgacgccg tcaccgcgga cctcgccgcc
    17401 ctcaagcggg ccctggaaaa gggctgatca gcgcctcacc ccacccgtac gcggtcgctg
    17461 tccccgtcgg acaggaacag ggccaggtgc ccgccctcct ccagcacggc ggcacgttcg
    17521 gcccggccga ggccgcgcag cggggagacg tccaccgtgc ccgcgtccac ggtccaggac
    17581 gcggcgacac ggccgtcgac cagcaccacc cgcgcgccct gcaccgagag gccgcggtgg
    17641 gcgtcgtcga tgatccggct ccggtcctgg tagccgagga tcgcgttgtc gaaggcgggc
    17701 aggaaccgca ccggtgcggg tgtgccgggg tccgggcgcg gcgcgtcggg caggtcgagc
    17761 agttcccggc cacgctcgtc ccggaaggcg accagccggt cccggaccgc cgccaccgcg
    17821 gcgggcagcc ccgccagccc gcaccaggcc cgcagatcgg ccgaggccgc cgggccgtac
    17881 gccgccaggt agcgcagcac cagcgcctcc cccgccgcgt cggcccccgg ccggccgggc
    17941 ggatccggct cacggcccag ccagtgggcg agcggggtgt tgcgcacccc ggccttcaca
    18001 cgccacgtcc cgcgcggcgg gagctggacc atcgggacga gggccgccac cgccatctcc
    18061 cccagcggcc gccggccggg cgccggccag cggtcggcga ggtgcagggc gatctccgtc
    18121 atcgtgcgcg gctcgccgtc cgccatgacg gcgcgcaccg ccgccgcgag cgcgtcgagg
    18181 tccacccctc cgagctcgcg acggtaggtc cccagcaccc gctgccgcag catcgcgcca
    18241 tgccgggccc gccacgcgag ggcgtcgtcg gcggtgacga ggtggacggt gcggcgcatc
    18301 agatgggtcc gcaccacgtg ccgcccggtg agcaggccgt ccagcgcctc cggggcgaag
    18361 ccgcgcagcc gcgaccagag cccgacgaag ggttcctgcg gctcctgcgc ctggaggccg
    18421 cacaggtggg cgacggcgtc caggggcggg agccgcgcac ggtccaggag cagctgccgg
    18481 gcgagcgtgg cccggttgag ctcccgggcg tccagggtct tcacccgccg tacccgctga
    18541 ccacgtccac gacccagacg acgccgtacc ggtccctgag catgccgtag agcggggccc
    18601 accgggcggg acccaacggc tggacgacgt ccgccccggc ggacagcttc tcccagtact
    18661 ccgtcacctc cgccgcgtcg tcgccgcgca cggagacgaa gaaggagttc tcgccccggt
    18721 cccagggcag ccgcgacggc acgtcgtagg ccatgacgcg gaagccgttc tccgccgtca
    18781 cctggcccca catcacctgg tccgcctcgg cggggtcgtc cacggccccg gcgtcctggt
    18841 agctgacgat ggcgaggtcg ccgccgaaca cggaccggta gaagtcgagc gcggcgcggg
    18901 cctcgccccg gaagttcagg tgggtcacgg acgtgacgga catgggatgg ctcctcgccc
    18961 tcggaacgca ggacccgcgg tcgcgccctg ccgttgtgcg atccacactc gcaggggtag
    19021 aggtcaggat gtggccgcta ctgccgggca gtatgagggc atgccgaaga cctccgcccg
    19081 actgctcgcg ctgctgtccc tgctccaggc ccgccgcgac tggccggggg cactgctcgc
    19141 cgaacggctg gacatcagcc cgcggaccgt acgccgtgac gtcgaccgcc tgcgcgaact
    19201 gggctacccc atcgcggcct tcaaagggcc cgagggcgga taccggctac aggccggtac
    19261 ggagctgccc ccgctgctct tcgacgacga acaggccgtc gcgctcaccc tcgccctcca
    19321 ggtcgtcacg gccaccggcg ccggggtcga ggaggccgcg gcccgcgcgc tgaccaccct
    19381 ccggcaggtc atgcccgcac ggctgcgcca ccgcgtcgac gccctccagg tcacggcggt
    19441 cgaccccgcc ccgacgggag ggcgccccca ggccggcggc gggacgctca tggcgctcag
    19501 ctccgccgtc cacgcccgcg aggtactgcg cttcgactac accgccggca ccggtgcgcc
    19561 ccggcgggcc gagccccacc acctcgtcac ctacgccgga cgctggtacc tcgtcgcctg
    19621 ggacctcgac cgcgaggact ggcgcacctt ccgcgccgac cggatcagcc cgcgcgtccc
    19681 cacgggcccc cgcttcgccc cgcgcgaggt gcccggaggc gatgtggcgg cgttcgtggc
    19741 cggccggttc cgcggcgcgg acgcccacgg cgactggccc tgccacggcg aggtggtcct
    19801 ccgcaccgcc gccgccacgg tggcccccta cgtccgggac gggctcgtcg aagcactcgg
    19861 ccccgaccgc tgccgcctcg tcctgggcgc ctggtcctgg accgccctgg ccgccaccct
    19921 cggcaggttc gacgccgaca tcgaggccgt cggcccggac gaactacgga gggccttcgc
    19981 ccggttggcc cgccgctacg ccgacgcggc gacggaccac cggcccccgc cgcccggacc
    20041 gtgacgccgg gcgggcccgc ccccgcccgc cgggaggggg cgccggatca gcgccccgcg
    20101 gtcagccgcc gcgcgacctc cgtcgcccag tacgtcagga tcatctgcgc gcccgcgcgg
    20161 cggataccgg tcaggctctc caggatcgcc gcgtcccggt cgatccagcc cttctccgcg
    20221 gcggcctcga tcatcgcgta ctcgccgctg atctggtacg ccgccaccgg cacgtccacc
    20281 gcgtcggcga ccttggccag gatgtccagg tacgggccgg ccggcttgac catgaccatg
    20341 tcggcgccct ccttcaggtc gagcgccagc tcgcgcagcg actcgcggac gttcgccggg
    20401 tcctgctggt acgtcttgcg gtcgcccctg agcgaggagc ccaccgcctc acggaacggg
    20461 ccgtagaagg cggaggagta cttcgccgtg tacgcgagga tcgacacgtc ctcgtggccg
    20521 gtctggtcca gcgcgtcgcg gatcaccccg acctggccgt ccatcatgcc gctggggccc
    20581 accacatggg cgcccgcgtc ggcctggacc tgggccatct ccgcgtaccg ctccagcgtg
    20641 gcgtcgttgt cgacgcggcc gtccccggtc agcaccccgc agtggccgtg gtcggtgtac
    20701 tcgtccaggc acaggtcgga catgacgacc aggtcgtcgc ccacctcttc gcggaccgcg
    20761 cgcaggccca cctggaggat gccgtccggg tcggtgcccg ccgtgccccg ggcgtccttc
    20821 ttctcgtcca gcgggacgcc gaagagcatg atccccgaga caccggccgc gaccgcgtcg
    20881 accgcggcct tccgcagggt gtccagggtg tgctgctgca cgcccggcat ggccgagatg
    20941 gcgaccgggg cgtcgatgcc ctcacgcacg aacgcgggca ggatcaggtt cgcggggtcg
    21001 agccgggtct cggcgaccat gcgccgcatg acgggggtcg tccgcagccg ccgggggcgg
    21061 gagccgggga agtttcc
//
