LOCUS       NC_015953              31096 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. SirexAA-E, complete sequence.
ACCESSION   NC_015953
VERSION     NC_015953.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Streptomyces sp. SirexAA-E
  ORGANISM  Streptomyces sp. SirexAA-E
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7414440)
  AUTHORS   Takasuka,T.E., Acheson,J.F., Bianchetti,C.M., Prom,B.M.,
            Bergeman,L.F., Book,A.J., Currie,C.R. and Fox,B.G.
  TITLE     Biochemical properties and atomic resolution structure of a
            proteolytically processed beta-mannanase from cellulolytic
            Streptomyces sp. SirexAA-E
  JOURNAL   PLoS One 9 (4), e94166 (2014)
   PUBMED   24710170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Streptomyces sp. SirexAA-E
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2011) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. SirexAA-E
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            environment                       :: Soil, Terrestrial
            num_replicons                     :: 1
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly                          :: Newbler v. 2.3 (pre-release)
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi05895
            Funding Program                   :: DOE-GLBRC 2008
            Source of Isolate :: Cameron Currie (currie@bact.wisc.edu)
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method                   :: Newbler v. 2.3
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000177195.2-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 02:12:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,619
            CDSs (total)                      :: 6,532
            Genes (coding)                    :: 6,385
            CDSs (with protein)               :: 6,385
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 61 of 147
            Pseudo Genes (incomplete)         :: 120 of 147
            Pseudo Genes (internal stop)      :: 8 of 147
            Pseudo Genes (multiple problems)  :: 39 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2462211
            Orig. end                         :: 2493307
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002993.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086644
            Source DNA and organism available from Cameron Currie
            (currie@bact.wisc.edu)
            Contacts: Cameron Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31096
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /region_number="11"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..31096
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..23234
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23234
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13234](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13234
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(1003..1019)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.15"
                     /tool="antismash"
     gene            1003..1383
                     /locus_tag="SACTE_RS10885"
                     /old_locus_tag="SACTE_2206"
     CDS             1003..1383
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574976.1"
                     /locus_tag="SACTE_RS10885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2206"
                     /product="VOC family protein"
                     /protein_id="WP_014046086.1"
                     /transl_table=11
                     /translation="MACRISELVLGCRDPEVLARFWCEVLDFVVLDREGDDCFEIGPRE
                     GFGGPQPTIILSRRDEPEPGKTRLHIDVNATDRDQDAELERLLELGARPADIGQTGEEQ
                     WHVLADPEGNEFCLLKARLNPL"
     gene            complement(1584..1856)
                     /locus_tag="SACTE_RS10890"
                     /old_locus_tag="SACTE_2207"
     CDS             complement(1584..1856)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046087.1"
                     /locus_tag="SACTE_RS10890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2207"
                     /product="hypothetical protein"
                     /protein_id="WP_014046087.1"
                     /transl_table=11
                     /translation="MAHDERHRSHEHPQAPWWWGTGPVGAALLVVVGVAGVLWAFLGSA
                     EDDPVGGYGASKVVAIGAVLLGTAVLERFRSRRSRAQGTEDGQNG"
     gene            complement(1894..2199)
                     /locus_tag="SACTE_RS34245"
                     /old_locus_tag="SACTE_2208"
     CDS             complement(1894..2199)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SACTE_RS34245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SACTE_2208"
                     /product="hypothetical protein"
                     /protein_id="WP_014046088.1"
                     /transl_table=11
                     /translation="MVSEISHFRLPLAGTEWLEIVHVDDLTELEALVDRMNRVSGAKSN
                     HGEATVLAWAEVHGATEECQDWETLSFRGPATAGKAEPRHRQPDGPRHASLLFPGP"
     gene            complement(2424..2951)
                     /locus_tag="SACTE_RS10900"
                     /old_locus_tag="SACTE_2209"
     CDS             complement(2424..2951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046089.1"
                     /locus_tag="SACTE_RS10900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2209"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_014046089.1"
                     /transl_table=11
                     /translation="MEESADEASRARYRLDARLEEHARHAEWLVGHGYLVPPASDVRLR
                     RTPDLVDPVALAAAARQVAGCPSGPLGAPADVLERFGLYPTAVDEAAEGASLLLKGYGV
                     AVISGQVTPGRRRWTAAHELGHHLMQDEYHSDAGVAAGRDEGERLIDRFVEEFLLPEAD
                     VRRVWSDGERDG"
     misc_feature    3009..3021
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    3010..3019
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.41"
                     /tool="antismash"
     CDS             complement(3088..3237)
                     /gene="allorf_2465299_2465448"
                     /locus_tag="allorf_2465299_2465448"
                     /protein_id="allorf_2465299_2465448"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPRSGGVRVALQGARWRPRGTVRADCLPAGRARPAHGLSGAPTGC
                     FRLP"
     CDS_motif       complement(3196..3237)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPRSGGVRVALQGA"
                     /locus_tag="allorf_2465299_2465448_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3088..3195)
                     /prepeptide="core"
                     /locus_tag="allorf_2465299_2465448_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.60"
                     /molecular_weight="3703.3"
                     /monoisotopic_mass="3701.0"
                     /core_sequence="RWRPRGTVRADCLPAGRARPAHGLSGAPTGCFRLP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPRSGGVRVALQGA"
                     /leader_location="[3195:3237](-)"
                     /alternative_weights="3721.3"
     gene            3285..4022
                     /locus_tag="SACTE_RS10905"
                     /old_locus_tag="SACTE_2210"
     CDS             3285..4022
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (63-170). E-value: 1.4e-07. Score:
                     21.8. Matches aSDomain: nrpspksdomains_SACTE_RS10905_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046090.1"
                     /locus_tag="SACTE_RS10905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2210"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_014046090.1"
                     /transl_table=11
                     /translation="MDRNVRSVEDVLRLMDGLFAPEADRWTSGAGAWWDGFYEDRSRPV
                     PFFVAKPDENLVSYVRRGLVAPGRALDLGCGPGRNSLYLASLGFTVDAVDLSPGAVAWA
                     EERAREAGADIRFRCGDAFAEGEGAPAGPYDLVHDSGCFHHLPPHRRVSYLALVDRVLA
                     PGGHLALNCFASGAMGSELPDAELYGTAELHGGLAYTPKSLRRIFAGLEEVELRRMRDE
                     PADSPWFGEEFLWSALFRRPDRP"
     aSDomain        3474..3794
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SACTE_RS10905_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.40E-07"
                     /label="SACTE_RS10905_oMT.1"
                     /locus_tag="SACTE_RS10905"
                     /protein_end="170"
                     /protein_start="63"
                     /score="21.8"
                     /tool="antismash"
                     /translation="LVAPGRALDLGCGPGRNSLYLASLGFTVDAVDLSPGAVAWAEERA
                     REAGADIRFRCGDAFAEGEGAPAGPYDLVHDSGCFHHLPPHRRVSYLALVDRVLAPGGH
                     LAL"
     gene            complement(4475..5308)
                     /locus_tag="SACTE_RS10910"
                     /old_locus_tag="SACTE_2211"
     CDS             complement(4475..5308)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577219.1"
                     /locus_tag="SACTE_RS10910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2211"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_014046091.1"
                     /transl_table=11
                     /translation="MSPELSRLSVNQETVRQLSLPELAESCAKAGVGQVGLWRAPVREY
                     GIERAGKLMKDAGLTVTSLCRGGFLTATGPAERARALEDNRAAVDEAAGVGTDTLVLVS
                     GGLPPGDKDLHGARERIADALAELAPYAGERGVRLAIEPLHPMFASDRCVVSTLSQALD
                     LAERFPAEQVGVVVDAYHIWWDDQVPAQIARAGAGGRIHSFQLADWITPLPAGVLVGRG
                     QLGDGSVDFRSLRRHVEATGFDGPIEVEIFNEDLWARDGAEVVAEVAARYLEHAC"
     gene            complement(5305..6447)
                     /locus_tag="SACTE_RS10915"
                     /old_locus_tag="SACTE_2212"
     CDS             complement(5305..6447)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969064.1"
                     /locus_tag="SACTE_RS10915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2212"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_014046092.1"
                     /transl_table=11
                     /translation="MTIHLPQGPYEPRTTPLDLAPNGAALASRTVFSAAHVVADPYADA
                     GPDDPAAVDWDATLAFRRHLWSHGLGVAEAMDTAQRGMGLDWAGAAELIRRSAAEAKAV
                     GGRIACGVGTDQLTGPATLAEVRAAYEEQLAVVEESGAQAILMASRALAAAADGPEDYL
                     ETYAHLLRQATEPVVLHWLGPMFDPALEGYWGSADLDAATDTFLEVIAEHPDKVDGIKM
                     SLLDAAREIDVRRRLPSGVRCYTGDDFNYPELIAGDDRGFSHALLGIFDPLGPLAAHAV
                     RVLDTGDTEGFRALLDPTVELSRHLFRAPTRYYKTGVVLLAWLAGHQDHFTMVGGLQSA
                     RPLPHLAKAYELADRLGLFPDPELAEARMRALLSVHGGTR"
     gene            complement(6485..7636)
                     /locus_tag="SACTE_RS10920"
                     /old_locus_tag="SACTE_2213"
     CDS             complement(6485..7636)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317389.1"
                     /locus_tag="SACTE_RS10920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2213"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_014046093.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 6.1e-11, bitscore:
                     41.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.1e-25,
                     bitscore: 88.6, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRRTVRIAMNGVTGRMGYRQHLVRSILAIREQGGLDLGDGEVLW
                     PEPVLVGRRAHALRALAEQHGLTEWSTDLDAVLADESIDIYFDAQVTSARVEAIKKAIA
                     AGKHVYTEKPTATDVEGALELARLARDAGIKHGVVQDKIFLPGLLKLKRLIDGGFFGEI
                     LSVRGEFGYWVFEGDWQEAQRPSWNYRAEDGGGIVVDMFPHWEYVLHELFGKVTTVSAH
                     VRTHIPQRWDEHGKPYAATADDAAYGTFQLAGGAVAQINSSWAVRVNRDELVEFQVDGT
                     HGSAVAGLRNCRVQHRSATPKPVWNPDLPVTESFRDQWQEVPDNAVFDNGFKAQWELFL
                     RHVVLDEPYTWDLMAGARGVQLAELGLRSAAEGRRFDVPELSL"
     misc_feature    7661..7672
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            7748..8812
                     /locus_tag="SACTE_RS10925"
                     /old_locus_tag="SACTE_2214"
     CDS             7748..8812
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380887.1"
                     /locus_tag="SACTE_RS10925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2214"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_014046094.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVATSTRDRVLRAVDELD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQSQIGGPGDGSGRAGGEKLAVV
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGALEDPSHQAAMAVKLAKLADAGTRIVFCG
                     RPPLPDSDAVTASLAFDNRGGARRLTEHLLELGHRHIGYVAGPLERTTTRHRLEGHREA
                     MKAAGLHGDEESLTVHGPYDRRSGYDATRELLAREGEVTAVVAANDTVALGACAAVRDH
                     GLRIPEDVSVAGFDDLPFSVDAMPALTTVRLPLAEAGARAGRLAVGKEKAPAGGIATID
                     AELMARGSTAAPRG"
     cand_cluster    8517..31096
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8517..31096
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[18516:21096](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(18517..21096)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     CDS             8831..9037
                     /gene="allorf_2471042_2471248"
                     /locus_tag="allorf_2471042_2471248"
                     /protein_id="allorf_2471042_2471248"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAAAPIGPGARPAGASRAYRPVRAWTASRSSCPPARHCRRGGTLG
                     AAAPPCGPRPTFVAGRSDEGPPR"
     CDS_motif       8831..8968
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAAAPIGPGARPAGASRAYRPVRAWTASRSSCPPARHCRRGGTLGA"
                     /locus_tag="allorf_2471042_2471248_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8969..9037
                     /prepeptide="core"
                     /locus_tag="allorf_2471042_2471248_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.40"
                     /molecular_weight="2199.4"
                     /monoisotopic_mass="2198.1"
                     /core_sequence="AAPPCGPRPTFVAGRSDEGPPR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAAAPIGPGARPAGASRAYRPVRAWTASRSSCPPARHCRRG
                     GTLGA"
                     /leader_location="[8830:8968](+)"
                     /alternative_weights="2217.5"
     gene            complement(9134..9712)
                     /locus_tag="SACTE_RS10930"
                     /old_locus_tag="SACTE_2215"
     CDS             complement(9134..9712)
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949729.1"
                     /locus_tag="SACTE_RS10930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2215"
                     /product="snapalysin family zinc-dependent metalloprotease"
                     /protein_id="WP_014046095.1"
                     /transl_table=11
                     /translation="MLDSRWFKAAGVTAAMTLATVTAAHAVPAPEPAAESSAAAVTLRY
                     DDSRAVGWEAAIAAGVASWNANVSNVKLVEAAPGTRAEIQIVATSGWPQATLGPVRPGG
                     QARVELGSQAVAEGHDKTRIAAHELGHSLGLPDTKPGPCSQLMSGSSAGTSCTNAVPNA
                     AERSRVQSAYAGGLVSRAPADGRVLVDAP"
     CDS             complement(9852..9983)
                     /gene="allorf_2472063_2472194"
                     /locus_tag="allorf_2472063_2472194"
                     /protein_id="allorf_2472063_2472194"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGGGGSGPGGAVRVGELPAVVGSRGISSDGCGVCFRPHFMSGA"
     CDS_motif       complement(9915..9983)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGGGGSGPGGAVRVGELPAVVGS"
                     /locus_tag="allorf_2472063_2472194_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9852..9914)
                     /prepeptide="core"
                     /locus_tag="allorf_2472063_2472194_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.40"
                     /molecular_weight="2030.3"
                     /monoisotopic_mass="2028.9"
                     /core_sequence="RGISSDGCGVCFRPHFMSGA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGGGGSGPGGAVRVGELPAVVGS"
                     /leader_location="[9914:9983](-)"
                     /alternative_weights="2048.3"
     gene            10001..13234
                     /locus_tag="SACTE_RS10935"
                     /old_locus_tag="SACTE_2216"
     CDS             10001..13234
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380885.1"
                     /locus_tag="SACTE_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2216"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_078492615.1"
                     /sec_met_domain="DUF4135 (E-value: 4.7e-106, bitscore:
                     353.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.2e-26, bitscore:
                     91.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGATPPCAARPSPAGWGPRRPPGPFVAGEVDAVAETDAIDGTTPP
                     GVPRASAAPGGTAVGPALGAPAHEHPGTLPAYGPDAGAETHDRALGTASLLAARERGGP
                     WWLPGVVGQPPVREPDWAVFVREAVAAAPAAPADVPVADRDYPGLTGFELVVAPFADRA
                     AERVAHAPSGRGAGPCPAAVLDGFRQDVAGRLARLAARTLVLELHEARTGGRLAGDGTR
                     ERFRDFLRLAGSRSRLGSLATRYPVLARVLAQTALDAADAFAEMLGRLAADREPLASSG
                     VLGSGGTPGGCGPEALTGVVPGAGDSHRGGRSVMLLRFADGTRLVYKPRPLAAHRHYTT
                     LVDWFNSLAGSPDLLTPRVLDRGAYGWAEFVEDGPCRSVEETALFYRRLGALLALLHVL
                     DGTDLHHENLIARGPHPVLVDVETLFHPPLAPTGFTDPAARALHASVHRVGLLPQLLVG
                     DTSALDVSAVGGGRAASSPVEGAGWAAAGTDTMHLVRTAGRFTESANRPRLDGVRTDPS
                     AFTDALCEGFRAAYTAVSDARDELLGENGLLRLFSRDEVRFVPRPTWAYATLLHESTHP
                     DLMRDATERQRVFALLRTGALGPSALPGLEDEEIAELWRGDVPVFTTRPDTTDLWSGTG
                     RAVPGPAGATGLERVEAKVRALDTVDRQDQERIIRTAMASTSTEPPHRAVTGGRARVAA
                     AAPEPERLLSAARSVGDQLVSLAYHDAGRTNWIGLELLGERYWRLTPMAADLACGYTGP
                     ALFLAQLASLTGESRYADTARAALSPVPGLLDALHQRVDDLGPLGSGAFAGLGGIAYAL
                     AEAGTLLDDPQVLDWAGPATRLSCAASSAEDGYGVRGGAAGGLVSLLAVHRTTGRAEAW
                     RGAERCAERIAAAPLPAAGGFADGAAGIGWALLRYAGAGGGPRYREAGLSALRRAVRGA
                     HEGQAWCEGTTGIALALADSPDALADPELSGWLAGRTGELAETGPLADDSLCHGELGVL
                     ELLGHGALPQARPHWLRRTGTLLAAADRAQPHCGTPGHVPHPGLLTGLSGIGHGLLRAG
                     FPDRIGSALLMRHSPGADHRTPELSTTDQ"
     misc_feature    13246..13259
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            13246..13443
                     /locus_tag="SACTE_RS10940"
                     /old_locus_tag="SACTE_2217"
     CDS             13246..13443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046097.1"
                     /locus_tag="SACTE_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2217"
                     /product="hypothetical protein"
                     /protein_id="WP_014046097.1"
                     /transl_table=11
                     /translation="MTQISESARYTDSTAAGEGAAEHPAGRVTLRSGGALGQRGRLLSM
                     ADGDAGYGPELPVTTFTGPF"
     gene            13523..16441
                     /locus_tag="SACTE_RS10945"
                     /old_locus_tag="SACTE_2218"
     CDS             13523..16441
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124639.1"
                     /locus_tag="SACTE_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2218"
                     /product="AAA family ATPase"
                     /protein_id="WP_014046098.1"
                     /transl_table=11
                     /translation="MAATSPVTIGRDEEIGQLDSALDAARRRSGRALFLLGEAGIGKSR
                     LVGECAYRAYGLGMPVLRGRAGSTGLVVPFRPLVEALSSHFRAAGIPTDPELVPYHPAL
                     SRLVPEWRNGTASGWTETVVELAEALLRLLSLLGRETGCVLLLEDLHDCDTETLAVVEY
                     LVDNLADLPVLLLGTLRPDPVTALDLARSAEQRRTAVVRELGALGDDEARALVAACLEA
                     PPEQLPPVVLRRLVERAEGSPYLIEVLLADLLDTGRLRRTENGWEAADLPDGGLPSRVL
                     RGWARRLDRLDEPVRDLLLTAATLGSQFSVPVLQTVTGMEDRALFTHLRSAVEMGVIAP
                     DGAAPDRYTFRHTLTAEALISTVAPAERAALARRAATAVENSGVPLEEDRRQLLASLEL
                     AAGNRAGAAVRFAEAGRRMLGAGSHGSAVVLLERAHSLAADADRSAVAESLAVARAESG
                     DLDGALALVGALPPVPARSQAAARRGDAHIKIAWVAVMAERAADTAGQIGAARELIGPS
                     PSPARCASLAVVDGHLSLLPGEEGRGDRKAVERAALDAARTAEAEGLPVVACQAWQLLA
                     LLRREEGFDAADMCLERMLTLATEHGLPLWRVEALVRLGANGFMRTGDAARLRSAREAA
                     AELGSLLLAQTVDALLAMNAVMCARWEEAAEVVERSVEVSARIGNLAAHRYLLLAGATT
                     AVHRGRRREAERWLTAFRRAGGEQSPLVPLRLGFCGAIGALLEEDRDRARAELEAVLAW
                     ERAHPSYYYLSGRHGLRPLLRVLAGEAGRAEYEAVAAAPGAALAWNRQFLDLAEAVLLG
                     REGQGAAAERRMAAFDIRSAVFPVARHLGLRLVADAALADGWGEPVSWLRGAEEFFYDA
                     GVQPVAAACRAALRQAGVSVTQHRDGRDRIPSPLRTHGVTPREYEVFVLLAERPGNQQI
                     ARRLSISPRTVEKHLASLLSKTGRANRAALCEFAAECLVDHA"
     misc_feature    13558..13572
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    14201..14203
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16520..16534
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.56"
                     /tool="antismash"
     gene            16656..18530
                     /locus_tag="SACTE_RS10950"
                     /old_locus_tag="SACTE_2219"
     CDS             16656..18530
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046099.1"
                     /locus_tag="SACTE_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2219"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_014046099.1"
                     /transl_table=11
                     /translation="MSRPAACPGPAGAVYFSLLGPLTAVVDGRPLPLGPRKQRLVLATL
                     LSRPNTPVPVDVLTDVVWPDAPPRTARKNLQVYVSAARTLFAAVDGGDRDRVVHGCGGY
                     RLRIEEGELDTLRFRALARAGRAAGERGDLRTAARLLREALDLWGERPPLHDLRDSDVV
                     AQEAERLEARCLTVYEEWAEAEIETGRAAVAVDGLRDLVERHPLRERLRAAWMNSLHQS
                     GRQSEALAVYDDYRQLLARELGLEPSPALAALYGRVLGRGASPRPSAGRKAACDVSLPA
                     DLRDFTGREDELARLLPVAGAPDGGVAVVTGPAGVGKSVLAVRAAHLLGEGFPDGRIHV
                     RARRQDGAARTRTDLLEELVRLCGADTPGRPDAAEAENTWQDWLSRHRALVVLDDVVDE
                     ASVRGLLPRTGRSSVVLTARGQLAGLAPVHRIALCVPEDGEALDLLERLIGPDRLRTDP
                     AAALRIVRACGALPLAVAVSGMRLAVLRHLPLAEYAARVEDPGAALDELVAGDVSVRSR
                     IAAGWQDLSARDRTALARLAGLSSDCGFTLERAMAALRRDERETIRAVEALIGTGAVTS
                     PAGEVTAHAAWYEVPRLLCLYARETAGHEDADAPGASRGPALQLLSRG"
     gene            complement(18517..21096)
                     /gene="lanKC"
                     /locus_tag="SACTE_RS10955"
                     /old_locus_tag="SACTE_2220"
     CDS             complement(18517..21096)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380882.1"
                     /locus_tag="SACTE_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2220"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_014046100.1"
                     /sec_met_domain="micKC (E-value: 3.9e-199, bitscore: 662.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGTQETQMYCLADRTYFETPARLPDEESRYRLDTDPPPAGWRRE
                     AVGLWTSLVPEHAEPAEQGWKIHVSTVPGEAEDTLRDTARICVRHGVPFKFLRSGRALS
                     VMADKYMNRSGAGKFIAVYPPDETVFLTLAGELSQALAGRSGPYVLSDLRIGDAPVYTR
                     YGAFVPRWCTDADGRRVLALRDPSGTLVPDERGVVFRTPAWVEVPEALRPHLAARAAAR
                     DDTFPYTVTEALQFSNAGGIYLAVDRETGRRVVLREARPHCGLDGAGDDAVTRLHREHR
                     ALTTLAGLDCVPEVYGVRTVWEHHFLIEEHIEGNTLLEEIVARFSLVRGEGSAAELATY
                     VAWTDSVVGELTRALEEIHARGLRFGDLHPSNVIVRPDGRIALVDFEYATALDDEDTPL
                     AGAQGLQAPPGTPGAEADAYALWATWLGMLMPVMEMAGLERAKALTLERWARRRYGLPA
                     GAGPRRPALLRGLDASRRREAEVAALFEGPDVDWAGVRARLLAGIHAGATPGRTDRLFP
                     GGPELFANGGTDLAHGAAGVLYALHRVGAPVPEEWTDWLARAALRRDPAGAGGFFDGLP
                     GTAVVLTLLGRAEQGRELWDRAASAAPPTAADLLTGRAGIALAALRMARAGGTDLDGKL
                     IDEALRTARDLDRLVRGEAVDGMRLPESAGLLRGLSGAALLDLELHTLTGETWLVRAAR
                     TALGREAGHIVGMPDGTLQVRHGRRHLLYLDQGSSGVALVSQAYETRHRAPALSALIPG
                     VRKGCVMEFVREPGLFTGRTGLVAAAAQLGPGPRTGGGVLASVRNLPWHLVADGDRLLV
                     PGRTLRRFSADLASGAAGVLLGLHFLSGGEGGAGQDPAGLLELLTLG"
     gene            complement(21173..22462)
                     /locus_tag="SACTE_RS10960"
                     /old_locus_tag="SACTE_2221"
     CDS             complement(21173..22462)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046101.1"
                     /locus_tag="SACTE_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2221"
                     /product="MFS transporter"
                     /protein_id="WP_014046101.1"
                     /transl_table=11
                     /translation="MTTPLRDNRDFRLLWMSGLFAVLGGQMSALALPLLVLKETGSAVQ
                     AGSVGTVSVGAVLIAMLPGGVMADRVERRRLMRLCDVGSLLVVTALATAVWFGHAPMAL
                     VLLVAAAGAVISSVYGPAVFGLMRAVVPADQMGTATARLQARTQTVRLVGPLVGGALFG
                     LHPALPFAAEALGLLLSTVCVALVRTRSRAETAAGPVFSRRELTAGLSFLWTIPYLRTI
                     LLIFGLGMNFAFGALTFTALSVFSEGGRSGVGGGFVITCVSAGALAGALLAPRINPDRY
                     SRALILATCWTCVAAAGTMAWLRNPLAAGAMCALCMCLSTIASIGFLSTLLIVTPEDRV
                     GRVQSGASFLSSLVQPFGPLAGGALLTAFGARWAFTLTGCVLAASALVVTFAPSARAEP
                     SPHDEAEPADPPEPGPGSTPAGARHAVPGD"
     CDS             complement(22459..22668)
                     /gene="allorf_2484670_2484879"
                     /locus_tag="allorf_2484670_2484879"
                     /protein_id="allorf_2484670_2484879"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MDRGIGLPRGARPVGEWGGSVVDGDRPVAASGPSRPGSAFRRTTA
                     PGFRPGGRPARTTCHDPMTTGSYR"
     CDS_motif       complement(22576..22668)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDRGIGLPRGARPVGEWGGSVVDGDRPVAAS"
                     /locus_tag="allorf_2484670_2484879_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22459..22575)
                     /prepeptide="core"
                     /locus_tag="allorf_2484670_2484879_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="3899.3"
                     /monoisotopic_mass="3897.0"
                     /core_sequence="GPSRPGSAFRRTTAPGFRPGGRPARTTCHDPMTTGSYR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDRGIGLPRGARPVGEWGGSVVDGDRPVAAS"
                     /leader_location="[22575:22668](-)"
                     /alternative_weights="3917.3"
                     /alternative_weights="3935.3"
                     /alternative_weights="3953.4"
                     /alternative_weights="3971.4"
                     /alternative_weights="3989.4"
                     /alternative_weights="4007.4"
                     /alternative_weights="4025.4"
                     /alternative_weights="4043.5"
     gene            complement(22694..22849)
                     /locus_tag="SACTE_RS34580"
                     /old_locus_tag="SACTE_2222"
     CDS             complement(22694..22849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046102.1"
                     /locus_tag="SACTE_RS34580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2222"
                     /product="hypothetical protein"
                     /protein_id="WP_014046102.1"
                     /transl_table=11
                     /translation="MSENTKPAADDNNETPEVEAHSVLDLQETAVDKVIAPGNCVSLVS
                     VVENAN"
     CDS             22868..23062
                     /gene="allorf_2485079_2485273"
                     /locus_tag="allorf_2485079_2485273"
                     /protein_id="allorf_2485079_2485273"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTALVPGGPEVPGSGGASRCPPLPRKLGGPACGTLRRRYGAGIAP
                     ARRGCTASRAARPRPARSG"
     CDS_motif       22868..22909
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTALVPGGPEVPGS"
                     /locus_tag="allorf_2485079_2485273_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22910..23062
                     /prepeptide="core"
                     /locus_tag="allorf_2485079_2485273_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="4995.8"
                     /monoisotopic_mass="4992.7"
                     /core_sequence="GGASRCPPLPRKLGGPACGTLRRRYGAGIAPARRGCTASRAAR
                     PRPARSG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTALVPGGPEVPGS"
                     /leader_location="[22867:22909](+)"
                     /alternative_weights="5013.8"
                     /alternative_weights="5031.8"
     misc_feature    23028..23042
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.37"
                     /tool="antismash"
     gene            23171..24265
                     /locus_tag="SACTE_RS10965"
                     /old_locus_tag="SACTE_2223"
     CDS             23171..24265
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046103.1"
                     /locus_tag="SACTE_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2223"
                     /product="radical SAM protein"
                     /protein_id="WP_014046103.1"
                     /sec_met_domain="PF04055 (E-value: 9.9e-13, bitscore: 47.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELGELVGRRPFPAAGLLLGLTRRCPLSCAHCSTGSDPTVREAPD
                     AGRLVRFVGSFTSENRPDVVMLTGGEPLLLPGLVEELSALARRAGSRTALLSGMFFARS
                     RHIPAPILRAITGVDHFSASLDVHHEREVGRADVFRALHRIREAGVAVSFHLTGTGASD
                     PYLADLTRDVEEEFGGQVPSLVNEVRPFGRAASWAGPARGTPDAGAASPCSMAAWPVVA
                     FDGAVLACCNQDTVDLRPAPAHLYLGHIATDDWAAVRRRALESPVLRMIRTVGPAHLAD
                     RSGVPPRGGTYCDGCRALGGDARVAATAGAVAAGAAGALLDLAAARRGAAQGPEGVVRR
                     HGCAAYAPLVVAGAPGAGAVGGSR"
     gene            24262..24996
                     /locus_tag="SACTE_RS10970"
                     /old_locus_tag="SACTE_2224"
     CDS             24262..24996
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046104.1"
                     /locus_tag="SACTE_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2224"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_014046104.1"
                     /transl_table=11
                     /translation="MSAARPSTSARLRVTLGLLDGELLAAMEHLWRPEDLLPRYRAYLC
                     AMHTVVRASVPLMLRARERARLLDACGDPVAGPLAAYLTEHIREEEGHDAWLLDDLLAA
                     GATPGDALRPMPEPVVAALAGSQYYWIEHHHPVALLGYIAVLEGYAPAATLTARIARTT
                     GLPDAALRTVREHAALDTGHLDDLHALLDRLPLTEGQQADVTVSAMHSLDALARLFVRL
                     GRSGTAPPPRGAGHPSPMGVSP"
     gene            24993..25214
                     /locus_tag="SACTE_RS10975"
                     /old_locus_tag="SACTE_2225"
     CDS             24993..25214
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959336.1"
                     /locus_tag="SACTE_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2225"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_014046105.1"
                     /transl_table=11
                     /translation="MTRPPESDDEQPVLPDALYEAGLPVDLLSHEQRLVLSRLTPQELG
                     VLLDIKSRLDAVEPEVQAHGEIAGGALF"
     gene            25291..28476
                     /locus_tag="SACTE_RS10980"
                     /old_locus_tag="SACTE_2226"
     CDS             25291..28476
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156177.1"
                     /locus_tag="SACTE_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2226"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_014046106.1"
                     /transl_table=11
                     /translation="MTCPSCRQDLPPDARFCSSCGTPCATAPAPGDDERKPVTVLFCDL
                     VGSTALSGVLDPETLRTVTLRYFEAMSDRIVAEGGTPEKFIGDAVMAVFGVPVVREDDA
                     RRALAAALGMRDALAELNEELHAALGIRLATRIGVNTGQVVAGGDATARQALVSGETVN
                     IAARLEQNAAAGEILIGPDTLLAAGPTVSAEPTGPLRLKGKQDSVEAYRLLALGTDDPA
                     QLRRFDVPFVGRSAEQEALDAALADTVRCGRAGLLRVTGEAGVGKTRLVREWLARRSAS
                     GELAYGAGRCRSHGEQGTLTPLADALRALPALAGGPVDASGAVDASGAAVEDDAAALLS
                     AGLLRDGTPNAPFEDMCAALTTVLARAARARPVVVVLDDAHAAAPLLLRTLDRLTEGAG
                     PPGVLVVCVGRPDGTADGAGGLPVTGLPPEEAARLAALLARLDGRDGPVDERLLARAEG
                     NPLYLEQLLVDGRADGVGAGGPDAGLPPTLQALLGARIGALARAERTTVDLAAVIGREF
                     TAAELVLLEVSARLAERPPPAVVAVPSGERARRLARVEEVLAALGRRRLVEPAPAGDPE
                     TAAYRFSSGLVHEVTYGSLSKRAKADRHAWAAELPSVLRAGDGAVGGHLERAYRYRAEL
                     GLLDEATGRLRGRAARALGRAGAQAAARSDLPWAHSLLERAVGLDPDDAASVRRLGEVR
                     VALGDTEAGTALLRRVRDLESAPVEAAHARLALVVLDPGGPGPGLTATARAVLPVFEAA
                     GDSVGRARAHLRLAQRLQQAGRHEEAERDQARALEQAVLAGAEPERAGALGAIGISLWR
                     GPVPAPDAVERCRALLAAHGGGRPTVRLTLNCPLAVLYALQDRPREAHGCLAEADELAE
                     KLRFAEAEVFLPVFRAAVESLLGRGPVALELLARADAAARHTGAAGMRTAVALDAARIE
                     LDSGRTRRAATRLAGIGDGTELSHADAVDLRGMRGRLSAAEGRAFEAVGHADRAVAASL
                     LTDSPLVQATAELDRARTLDALGRRAQARASARTAAARFAAKGHLPGVRRAARCVPEEP
                     VPEGNALTTRERS"
     gene            28480..29364
                     /locus_tag="SACTE_RS10985"
                     /old_locus_tag="SACTE_2227"
     CDS             28480..29364
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946474.1"
                     /locus_tag="SACTE_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2227"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_014046107.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.9e-22, bitscore:
                     78.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVTTTGTAAGQGLTWSLRGRGPEDVPVPADPGPPGGRPARRATG
                     RGVRVCVVDSGVERDHPLVGTVDGSWVVVKDGESGAITVEPTTTGDTCGHGTACAGIIR
                     RTAPDCEIHSVRVLGERFSGTGDVLMAGLRWAVEQRFDVVNLSLSTTRTRFAPELHHLA
                     DRAYFARTVIVASAHNTPVESFPWRFASVISVGSHQEDDPELHLYNPEPPVEFFGPGQN
                     VTVPWLGGRTIRTTGNSFATPYVAGLCARVLSAHPSMTAFQLKNALYLSAANVHAGPRP
                     STAAGDIRDDSEN"
     gene            29366..29944
                     /locus_tag="SACTE_RS10990"
                     /old_locus_tag="SACTE_2228"
     CDS             29366..29944
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046108.1"
                     /locus_tag="SACTE_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2228"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_014046108.1"
                     /transl_table=11
                     /translation="MTLTPSPAPGDAARRELLQSVVDVARAIFGAAASSVFLLDEEADE
                     LVFQAVSGEGEEFLVGRRFPAGRGIAGWVVTSGEPMVVDDLSSDASFDRALAESTAYVP
                     DAIMAAPLISDSRVLGVLEVLDPSPQARSGVRELDLLAMFARQAAAALRVLAPAPAGVP
                     EAGRTLDGARREDALELLGSLERLLRGTG"
     gene            30022..30810
                     /locus_tag="SACTE_RS10995"
                     /old_locus_tag="SACTE_2229"
     CDS             30022..30810
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959340.1"
                     /locus_tag="SACTE_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_2229"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_014046109.1"
                     /transl_table=11
                     /translation="MKLAFSTLGVPGMSVTEVVRLAAANGYQGVELRAHPEEPVHPGLT
                     PLERGSVAEEFKRGGVEVLTVAGYARVAAEGDDEPVLAELAGLVELARDLGAPYVRVFP
                     GGGGLDPDEADATAARRLGAAAPHAADLGVRILLETHDSHRAGADVARVVGTVGHGSIG
                     AIWDVMHTWLAGEEAPASHAVLAPHLGYVQVKDIASVEDTTPLALGAGVLPLRTCLDGL
                     DPDAWVCWEYEKRWYPEAAELPGLLAEGREYLLRLGAPKQ"
     misc_feature    30023..30037
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 ggtgacgcgc ttctacgacg aactggccga cgactaccac ctgatctata cggactggga
       61 cacgagcatc cgtcggcagg gagactcgtt ggacgccttg atcggccagg agcgagtggc
      121 ggtcctcgac tgttcctgcg gcatcggcac ccaggccatc ggcctggcac tgcgcggaca
      181 ccgagtcacc gggaccgacc tcagcccccg cgccgccgcc cgagctgccc gcgaggccgc
      241 ccgctggaac ctgagcctgc gcacggccgc cgccgacatg cgacgcctcc cgttccctga
      301 cggccggttc gacaccgtcg tctgcgccga caactcgctg cctcacctgc tgaccgagca
      361 tgatgtgcgc gcggccctga ccgagatgcg acgtgtgctg cgtcccggcg gcctgctgct
      421 ggtcagcaca cgcgactacg acgacctgct gcgcgaccgc ccggcctcga cgcctccgca
      481 ggtccacggg aacgtcgact gcgccgacgg cgaggagcga accgtcacct tccagctctg
      541 gcactggcac gacgacggcg agcactacga cctggagcac ttccaactcc gcccggcgga
      601 cggggaatgg cgcgcccagg tccgccgtac cacgtactgg gcactcggcc gggaccggat
      661 ggcatccctc gcggccgagg ccgggttcgt cgatcccgag tggcggatgc cgcaggagac
      721 gggcttcttc cagccgctgc tcgtggcccg cgccggcggg taggtgactc cgcctcccgg
      781 cacgggaggc cggacaccag tcggcctcgg gacctcccac gcgtgatcgg gtgcacgcct
      841 gtccccctgc ccagcgaccc tgacggcgag gcgagggccc cgaaaacctc tcgcacccgc
      901 tcgccctgcc cgatacggtc accggcgtgt tcccgtgcgt tgagcccagg agctccgccc
      961 acggccgtcc ccgcagtccc ccgctgaaag caggtcacgt ccatggcatg tcgtatcagt
     1021 gagctcgtgc tcggttgccg cgaccccgag gtgctggctc ggttctggtg cgaggtcctg
     1081 gatttcgtcg tgctcgatcg cgagggggac gactgcttcg agatcggccc gcgcgagggg
     1141 ttcggcggcc cgcagccgac gatcatcctc agccgcaggg acgagccgga gccggggaag
     1201 acccggctgc acatcgacgt caacgccacc gaccgcgatc aggacgccga gctcgaacgc
     1261 cttctggagc tcggcgcgcg cccggccgac atcggccaga ccggcgagga gcagtggcac
     1321 gtcctggccg accccgaggg caacgaattc tgcctgctca aggcccgcct caacccgctc
     1381 tgacgggttc tgagccccgg cacgccctag gacttgtgtc aaaagtcccg cctgtccggc
     1441 gacgcctggc acgcaccctc gcggcgttac cgggatcacc ccgatacatc cagtatcggg
     1501 gcgaccctcc gccttgcgat cgcacgcacc agacgccgcc ggacccgccc tccgggcgga
     1561 cggcgctact ttcgcaacaa gccctagccg ttctgcccgt cctccgtccc ctgcgcgcgc
     1621 gaacgacggc ttcggaagcg ctccagcacg gctgtgccga ggagcacggc tccgatggcc
     1681 acgaccttgc tcgccccgta gccgcccacc ggatcgtcct cggcggaccc caggaacgcc
     1741 cacagcacac cggcgacccc gacgacgacg aggagagcgg ccccgaccgg accggtaccc
     1801 caccaccacg gcgcctgggg gtgttcgtgg gaccggtggc gttcgtcgtg tgccaaggct
     1861 gttctcccat gcgtcaggcg ggtaccggcg ccgtcacggg cccgggaaca ggagagacgc
     1921 gtggcgcgga ccatctggtt gcctgtggcg cggctctgcc ttgccggctg tcgcaggccc
     1981 tcgaaaagag agcgtctccc agtcttggca ctcctccgtc gcgccgtgca cctcggccca
     2041 ggcgaggacg gtggcttcac cgtgattcga cttcgcaccg gatactcggt tcatccggtc
     2101 gaccagtgct tccagttcgg tcaggtcgtc gacgtggacg atctccagcc actctgttcc
     2161 ggccagtggc agacggaagt ggctgatctc gctgaccacc gcctgggtcg tgacgtttct
     2221 acgggtacgg ccctgatggt tccgggcgat gtcgcccaga gtctcgatat gcccgccttg
     2281 atggcgtgaa gtagaggaga ggtgtcccag acgaggagcg aacccggtaa ccgcctgggg
     2341 ctcatcgaac gtgttctgtt gacgacggcg ctccacgaca tccggtacga ggccgagagg
     2401 gcgatcatgg tcgtcctggg tgcctatccg tctcgttcgc cgtccgacca gacgcgccgc
     2461 acgtcggcct cgggcagcag gaactcctcg acgaaccggt cgatgagccg ttccccctcg
     2521 tcccggccgg ccgccacgcc ggcatcgctg tggtactcgt cctgcatcaa gtggtgcccg
     2581 agttcgtgcg cggccgtcca gcggcgccgc cccggcgtga cctgaccgct gatcaccgcc
     2641 accccgtaac ccttgagcag gagtgaggcg ccctcggccg cctcgtcgac cgcggtcgga
     2701 tacaggccga agcgctccag gacatcggcc ggcgccccca gagggcccga agggcacccc
     2761 gcgacctgcc gagccgcagc cgccaacgcg accgggtcga cgaggtccgg cgtgcgccgc
     2821 aggcggacat cggatgccgg ggggacgagg tagccgtggc cgaccagcca ctcggcgtgg
     2881 cgggcgtgtt cctccaggcg ggcgtccagt cggtaccgcg cacgggatgc ctcgtccgcg
     2941 ctttcctcca acgtgcttcg gcgatccgct cgcccacgtc cgtccagctc cgcgcggcat
     3001 gcatgtgtgt gctttttgca cacctcccgc cccgaaggtg cccccggcgc cgccccccgc
     3061 gcccgggatc cacgcggaaa acagggctca ggggagccgg aaacaccccg ttggcgcccc
     3121 ggaaaggccg tgtgcggggc gtgcccgacc ggccgggagg cagtcggcgc gcaccgtgcc
     3181 ccggggcctc caccgcgccc cctggagagc cacccgcacc cctcctgacc tgggcatacg
     3241 cgagctctgc ggctagagtc caggcatcgg aaagggggtt ccggatggac cggaatgtgc
     3301 gctcggtcga ggatgtgctg cggctcatgg acggcctgtt cgcgccggag gccgaccggt
     3361 ggaccagcgg ggcgggcgca tggtgggacg ggttctacga ggaccggtcg aggccggtgc
     3421 cgttcttcgt ggcgaagccg gacgagaacc tcgtgtccta cgtccgacgg ggcctggtcg
     3481 ccccgggccg cgccctggat ctcggctgcg ggccggggcg caacagcctg tatctcgcct
     3541 cgctcggctt cacggtggac gccgtcgatc tgtcgccggg ggccgtcgcg tgggccgagg
     3601 agcgtgcccg ggaggcgggg gcggacatcc gcttccggtg cggcgacgcc ttcgccgagg
     3661 gtgagggcgc gccggccggg ccgtacgacc tcgtccacga ctccggctgc ttccaccacc
     3721 tgccgccgca ccggcgcgtc agctacctcg ctctcgtgga ccgcgtcctc gcccccggcg
     3781 ggcacctggc cctcaactgt ttcgcctccg gcgcgatggg gtccgagctg cccgacgccg
     3841 agctctacgg cacagccgag ctgcacggcg ggctcgccta cacgcctaag tccctgcgcc
     3901 gcatcttcgc ggggctggag gaggtggagc tgcgccggat gcgggacgag ccggccgact
     3961 ccccgtggtt cggtgaggag ttcctgtggt cggcgctgtt ccggcggccg gaccggccct
     4021 gagtcgcggg gcgggacgcg ttcggtcgag acctcggtgg cctccacctc ggccaggtgc
     4081 tccgggacgt cctacacgct cggcttcacc acgtcgtcga aggtgacggt ggtgccgaag
     4141 gtcgggtacg ccctgagtgg gtcgggccag gggccgcgcg gaaccgtcgg cgtgacgggc
     4201 gaccggcccc accggcacct cggccgcatc tggggcggcc cgccgcgtct tcgacgctcc
     4261 ggacgcctga acgaccggac cggcacggca ggtcccggaa agccgaatgg ggcccggcca
     4321 taaggccgga cccccctcgc tttccccctc cgccgggtct tcccgttccc cccggacccc
     4381 tccccggaag ccccgacgcc gaatacgacc ggggagggta cggaaaggtt gcacgccttt
     4441 acgttctctt taccaacggg gtggtgaagg cccctcagca ggcgtgttcg aggtagcggg
     4501 cggcgacttc ggcgaccacc tcggcaccgt cacgcgccca caggtcctcg ttgaagatct
     4561 cgacctcgat cggaccgtcg aacccggtcg cctcgacgtg ccgccgaagg gagcggaagt
     4621 ccacgcttcc gtcgcccagt tgcccccggc ccacgagcac gcccgccggg agcggggtga
     4681 tccagtccgc cagctggaag gagtggatcc ggccacccgc gcccgcccgt gcgatctgcg
     4741 cgggcacctg gtcgtcccac cagatgtggt acgcgtccac gaccacgccg acctgctcgg
     4801 ccgggaagcg ctccgcgagg tccagggcct gggacagggt ggagaccacg cagcggtccg
     4861 acgcgaacat cgggtgcagc ggctcgatcg cgagccgtac accccgttcc cccgcgtacg
     4921 gggcgagttc ggcgagggcg tctgcgatgc gctcgcgggc gccgtgcagg tccttgtcgc
     4981 cgggcgggag cccgccggag accaggacca gggtgtcggt gcccacgccc gccgcctcgt
     5041 cgaccgccgc ccggttgtcc tccagggcgc gggcccgctc ggcagggccg gtcgcggtga
     5101 ggaagccgcc ccggcagagg ctcgtgacgg tgagcccggc gtccttcatc agcttgccgg
     5161 cgcgctcgat cccgtactcc cgcacggggg cgcgccacag gccgacctgg ccgacgcccg
     5221 ccttggcgca gctctcggcg agttcgggca gggagagctg cctgacggtc tcctggttga
     5281 ccgacagacg ggagagttcg gggctcatcg ggtgcctcca tggacggaca gcagcgcgcg
     5341 catccgggcc tcggccagct cggggtcggg gaacaggccg agccggtcgg ccagttcgta
     5401 cgccttggcc aggtggggca gcgggcgggc ggactggagg ccgccgacca tcgtgaagtg
     5461 gtcctggtgg cccgccagcc aggcgaggag gaccacgccc gtcttgtagt agcgggtcgg
     5521 cgcccggaag aggtgccggg acagctcgac cgtggggtcg agcagggcgc ggaagccctc
     5581 ggtgtccccg gtgtccagga cgcgtacggc gtgggcggcc agcgggccca gcgggtcgaa
     5641 gatgcccagc agggcgtggc tgaagccccg gtcgtcgccg gcgatcagct cggggtagtt
     5701 gaagtcgtcg ccggtgtagc agcggacccc gctcgggagg cggcggcgga catcgatctc
     5761 gcgggcggcg tccaggagcg acatcttgat gccgtcgacc ttgtccgggt gttccgcgat
     5821 gacctcgagg aaggtgtcgg tggcggcgtc caggtcggcg gagccccagt agccctccag
     5881 cgcggggtcg aacatcggcc cgagccagtg caggacgacg ggttcggtgg cctggcgcag
     5941 gaggtgggcg taggtctcca ggtagtcctc ggggccgtcg gccgcggcgg ccagcgcgcg
     6001 ggaggccatc aggatggcct gggcgccgct ctcctcgacg acggcgagct gctcctcgta
     6061 ggccgcgcgc acctcggcga gcgtcgcggg gccggtgagc tggtcggtgc cgacgccgca
     6121 ggcgatccgg ccgccgaccg ccttcgcctc ggcggcggag cggcggatca gctcggcggc
     6181 accggcccag tccaggccca tgccgcgctg cgcggtgtcc atggcctcgg cgacgcccag
     6241 cccgtgcgac cagaggtggc ggcggaaggc gagggtggcg tcccagtcga cggcggccgg
     6301 gtcgtcgggt ccggcgtcgg cgtacgggtc ggcgacgacg tgggcggccg agaagacggt
     6361 gcgggaggcg agcgcggcac cgttcggggc gaggtcgagc ggggtggtgc gcggctcgta
     6421 cgggccctgc gggaggtgga tggtcatggg gtcggctccg tcgctccggg ggtggtccgg
     6481 ccggtcacag ggacagctcc gggacgtcga agcggcggcc ctcggcggcg gacctcaggc
     6541 cgagctcggc gagctggaca ccacgggcgc ccgccatcag gtcccaggtg tagggctcgt
     6601 cgaggacgac gtggcgcagg aacagctccc actgggcctt gaagccgttg tcgaagacgg
     6661 cgttgtcggg gacctcctgc cactggtcgc ggaaggactc ggtgaccggc agatcggggt
     6721 tccagaccgg cttgggggtg gcggagcggt gctggacccg gcagttgcgc aggcccgcga
     6781 cggcggagcc gtgggtgccg tcgacctgga actcgacgag ctcgtcgcgg ttgacgcgga
     6841 ccgcccagga ggagttgatc tgggcgacgg cgccgccggc cagctggaag gtgccgtagg
     6901 cggcgtcgtc ggcggtggcg gcgtagggct tgccgtgctc gtcccagcgc tgcgggatgt
     6961 gcgtccggac gtgcgccgag acggtggtga ccttgccgaa cagctcgtgc aggacgtact
     7021 cccagtgcgg gaacatgtcg acgacgatgc cgccgccgtc ctccgcgcgg tagttccagg
     7081 acggccgctg ggcctcctgc cagtcgccct cgaagaccca gtagccgaac tcgccgcgta
     7141 cggagaggat ctcgccgaag aagccgccgt cgatgaggcg cttcagcttc agcaggcccg
     7201 gcaggaagat cttgtcctgg acgacgccgt gcttgatccc ggcgtcgcgg gccagccggg
     7261 ccagttcgag ggcgccctcg acgtcggtgg cggtgggctt ctcggtgtag acgtgcttgc
     7321 cggccgcgat cgccttcttg atcgcctcga cgcgggccga ggtgacctgg gcgtcgaagt
     7381 agatgtcgat cgactcgtcg gcgaggaccg cgtccaggtc ggtggaccac tcggtcaggc
     7441 cgtgctgctc ggcgagggcc cggagcgcgt gcgcacggcg gccgacgagc acgggctccg
     7501 gccacagcac ctcgccgtca ccgaggtcga ggccgccctg ctccctgatc gcgaggatcg
     7561 agcgcaccag gtgctgccgg tatcccatgc gtcccgtgac gccgttcatg gcgatgcgca
     7621 ctgtcctgcg tgtcacgaaa gttccctcca tacagcggta gcaagcgctt tctatgcggt
     7681 atgacgctag cctgcgacag cgacccggac aagaggggcc gctccacgac tcccccggag
     7741 gagagcgatg acagtcacgc ttgcggacgt ggcggcccgc gcccgggtct ccccggccac
     7801 cgtgtcccgc gtactgaacg gcaactaccc ggtggccacg tccacccggg accgggtgct
     7861 gcgcgcggtg gacgagctgg actacgtact caacggtccg gccagctcgt tggcggccgc
     7921 gacgtccgac ctggtcggga tcctggtcaa cgacatcgcc gacccgttct tcgggatcat
     7981 ggcgggcgcg gcgcagagcc agatcggcgg gccgggcgac ggatcgggcc gcgcgggcgg
     8041 cgagaagctg gccgtcgtct gcaacaccgg cggctccccg gagcgtgaac tgacctatct
     8101 caccctgctc cagcgccagc gtgccgccgc ggtggtcctc accggcggcg cgctggagga
     8161 cccctcccac caggcggcca tggccgtgaa gctggcgaag ctcgcggacg cgggcacccg
     8221 gatcgtcttc tgcgggcggc ccccgctgcc cgactcggac gccgtcaccg cctcactggc
     8281 cttcgacaac cggggcggcg cccgccggct cacggaacac ctgctggaac tgggccaccg
     8341 gcacatcggc tacgtcgcgg gcccgctgga acgcaccacg acccggcacc gtctggaagg
     8401 ccaccgcgag gcgatgaagg cggcggggct gcacggcgac gaggagagcc tcaccgtcca
     8461 cggcccctac gaccggcgct ccggatacga cgccacgcgc gaactcctgg cccgcgaggg
     8521 cgaggtgacg gcggtggtcg ccgcgaacga cacggtggcc ctgggagcct gcgcggcggt
     8581 ccgggaccac ggactccgta tccccgagga cgtctcggtg gcgggcttcg acgacctgcc
     8641 gttctcggtg gacgcgatgc cggccctgac gaccgtacgg ctgccgctgg cggaggcggg
     8701 ggcgcgggcg ggccggctgg cggtgggcaa ggagaaggcg ccggccgggg gcatcgcgac
     8761 gatcgacgcg gagctgatgg cacgcgggtc gacggcggcc ccgcggggct gacgggacgg
     8821 gcggagaagc gtggcggctg ccccgatcgg gccaggcgcc cggcctgccg gggcatcgag
     8881 ggcgtaccgc ccggtcaggg cgtggaccgc atcccgatcc tcgtgtcccc ctgcccggca
     8941 ctgtaggcgc ggcggcaccc tcggcgccgc cgcaccgccc tgcggcccgc gaccgacctt
     9001 cgtcgcgggc cgcagcgacg aaggcccacc acggtgaccg gccggcgggg ccgaggcgtg
     9061 tcgaccgccc ggtaccaccc ggcacgtcgc ggactcctcg gcgcccggtg cccccctctc
     9121 gtcgcgcgac cggttacggc gcgtccacca gcacacgtcc gtcggccggg gcgcgggaca
     9181 cgaggccgcc cgcgtaggcg gactggacgc gggagcgctc ggccgcgttc ggcaccgcgt
     9241 tcgtgcagct ggtccccgca ctggatcccg acatcaactg ggagcacggg ccgggcttgg
     9301 tgtccggcag gcccagactg tggccgagct catgggcggc gatacgcgtc ttgtcgtggc
     9361 cctctgcgac cgcctggctg cccagttcca ccctcgcctg cccgccggga cggaccgggc
     9421 cgagtgtggc ctgcggccag ccgctggtgg cgacgatctg tatctcggcg cgggtaccgg
     9481 gcgcggcctc gacgagcttg acgttgctga cgttcgcgtt ccacgaggcg accccggcgg
     9541 cgatcgccgc ctcccagccg acggcgcggc tgtcgtcgta gcggagcgtc accgcggctg
     9601 ccgagctctc cgccgccggt tccggcgcgg gaacggcgtg cgccgccgtg accgtggcca
     9661 gggtcatcgc cgcggtgaca ccggccgcct tgaaccatct ggaatccagc atcgctgtcc
     9721 tttcgtccac gggaggctcg gctccgcgcg gagccgaacg agggagaggg ccggcggttc
     9781 gcggggcccg aaggactccg acggccgttt gcgctcctcc cggacggatc tgtgccgcga
     9841 tcccgccttg atcatgcacc tgacataaaa tgaggccgga aacagacccc gcacccgtcg
     9901 gacgagatac cccgcgagcc cacgacggcc ggaagctcgc cgaccctgac ggcgcctccg
     9961 ggcccgctac ccccaccgcc cacggcccgc ccccggaaag atgggggcca ctcccccatg
    10021 tgccgcccgc ccctcccccg caggatgggg tccgagaagg ccgccggggc ctttcgtggc
    10081 cggggaggtg gatgcggtgg cggagaccga tgcgatcgac gggacgacac cgcccggcgt
    10141 gccccgcgcc tccgcggccc ccggcggtac ggccgtcggc cccgcactcg gcgccccggc
    10201 gcacgagcat cccggcacct tgccggcgta cggccccgac gccggagccg aaacccacga
    10261 ccgggcgctc ggcaccgcgt ccctcctcgc cgcccgtgag cgcggcgggc cgtggtggct
    10321 gcccggtgtc gtcgggcagc cgcccgtacg tgagccggac tgggccgtgt tcgtccggga
    10381 ggccgtggcc gccgcaccgg ccgcgcccgc cgacgtcccg gtcgcggacc gggactaccc
    10441 ggggctgacc ggcttcgagc tggtcgtggc gccgttcgcg gaccgggccg ccgagcgggt
    10501 ggcgcacgcg ccgtccggac gcggcgccgg accctgcccc gccgccgtgc tggacggctt
    10561 ccggcaggac gtggccgggc gcctggcgcg gctcgcggcg cggacgctcg tcctggagct
    10621 gcacgaggcg cggaccgggg gacggctggc cggggacggg acgcgggagc ggttccggga
    10681 cttcctgcgg ctcgccggga gccggtcccg gctcggctcg ctggccaccc ggtaccccgt
    10741 gctcgccagg gtgctggccc agaccgcgct ggacgccgcc gacgccttcg cggagatgct
    10801 cggcagactc gcggccgacc gggagccgtt ggcctcctcc ggagtgctcg gcagcggggg
    10861 aacgcccggc ggctgcgggc ccgaggccct gaccggtgtc gttccgggtg ccggtgacag
    10921 tcatcgcggg ggccggtcgg tgatgctgct gcggttcgcc gacggtaccc gcctggtcta
    10981 caagccgcgc ccgctcgccg cgcaccggca ctacaccacg ctggtcgact ggttcaactc
    11041 ccttgccggc agccctgatc tgctgacgcc acgggtgctc gaccgggggg cgtacggctg
    11101 ggccgagttc gtcgaggacg ggccctgccg ctcggtggag gagaccgccc tcttctaccg
    11161 gcgcctgggc gcgctgctgg cgctgctgca cgtcctggac ggcaccgacc tgcaccacga
    11221 gaacctgatc gcccgggggc cgcaccccgt cctggtggac gtggagacgc tcttccatcc
    11281 gccgctggcc ccgacggggt tcaccgaccc ggccgcccgc gccctgcacg cctcggtcca
    11341 ccgggtcggg ctgctgccgc agctgctggt cggggacacg agcgcgctgg acgtgtccgc
    11401 cgtcggcggg ggccgggcgg cctcgtcgcc cgtcgagggc gccggctggg cggcggccgg
    11461 gaccgacacc atgcacctgg tgcgtacggc gggccgcttc accgagtcgg ccaaccggcc
    11521 ccggctcgac ggggtgcgga ccgacccgtc cgcgttcacc gacgcgctct gcgagggatt
    11581 ccgcgcggcg tacaccgccg tcagcgacgc ccgtgacgaa ctgctgggtg aaaacggcct
    11641 gttgcggctc ttctcccggg acgaggtccg cttcgtaccc cgtccgacct gggcgtacgc
    11701 cacgttgctg cacgagtcga cccaccccga cctgatgcgg gacgccaccg aacggcagcg
    11761 ggtgttcgca ctgctgcgca ccggcgccct gggcccgtcc gcgctgccgg ggctggagga
    11821 cgaggagatc gcggagctgt ggcggggcga tgtgcccgtg ttcaccaccc ggccggacac
    11881 cacggacctg tggagcggca ccgggcgcgc ggtgccgggc cccgcgggag ccaccgggct
    11941 ggagcgggtc gaggccaagg tccgggccct ggacacggtc gaccggcagg accaggaacg
    12001 gatcatccgg accgccatgg ccagtacgtc caccgagccc ccgcaccgcg cggtcaccgg
    12061 cggccgggcc cgggtggcgg ccgccgcacc cgaaccggag cggctgctct ccgccgcgcg
    12121 gtcggtgggc gaccagctcg tctcgctcgc ctaccacgac gcgggccgca ccaactggat
    12181 cggcctggag ctgctcggcg aacgctactg gcggctcaca ccgatggcgg cggacctggc
    12241 gtgcggctac accggccctg cgctcttcct cgcccaactg gcttcactga caggggagtc
    12301 gcggtacgcc gacaccgccc gtgcggccct gtcgccggtg cccggactgc tggacgccct
    12361 gcaccagcgg gtggacgacc tcggtccgct cggttccggc gccttcgcgg gcctcggcgg
    12421 tatcgcgtac gccctggccg aggcggggac gctgctcgac gacccgcagg tgctggactg
    12481 ggcgggaccg gccaccaggc tgagctgcgc ggcgagttcg gccgaggacg ggtacggggt
    12541 gcgcggcggg gcggcgggcg ggctggtgtc gctgctcgcg gtgcaccgga ccaccggccg
    12601 ggcggaggcg tggcggggcg ccgaacgctg tgcggagcgg atcgccgcgg caccgctgcc
    12661 ggcggccgga ggcttcgcgg acggggcggc gggcatcggc tgggcgctcc tgcggtacgc
    12721 cggcgcgggc ggcggtccgc gctaccgcga ggcggggctg agcgccctgc ggcgcgcggt
    12781 acgcggcgcc cacgagggcc aggcgtggtg cgagggcacg acgggcatcg cactcgcgct
    12841 cgccgacagc cccgacgccc tggccgatcc cgagctgtcc ggctggctgg cgggccggac
    12901 cggcgagctg gccgagaccg gcccgctcgc cgacgacagc ctctgccacg gcgaactggg
    12961 tgtcctggag ctgctgggcc acggcgccct gccccaggcc cgcccccact ggctgcgccg
    13021 gaccggcacc ctgctggccg ccgccgaccg ggcgcagccg cactgcggga cgcccggaca
    13081 cgtaccgcac cccgggctgc tcaccggcct gtcaggaatc gggcacgggc tgctgcgggc
    13141 gggttttccc gaccggatcg gctccgccct gctcatgcgc cactcccccg gtgcggacca
    13201 ccgcacccct gagttgtcga ccaccgacca gtaagtgagg cagagatgac gcagatcagc
    13261 gaatcggccc ggtacacgga ctccaccgcg gcgggcgagg gagcggccga acacccggcg
    13321 ggccgtgtga cgctccgctc cggcggggcg ctggggcagc gcggccgcct cctgagcatg
    13381 gcggacggcg acgccggata cggacccgaa ctgccggtga ccaccttcac gggcccgttc
    13441 tgatccctgg cccgacagcg cgtccgtccg gtggcgacca cgcctactgc cgcgcccggc
    13501 acggctccag tagcctgcgc ccatggcagc gacttcaccg gtcaccatcg gcagagacga
    13561 ggagatcggc cagctggaca gcgccctgga cgccgcgcgg cggcgttcgg ggcgcgcgct
    13621 gttcctcctc ggcgaggcgg gcatcggcaa gtcccggctg gtgggtgaat gcgcctaccg
    13681 cgcctacggg ttgggcatgc cggtgctgcg cgggcgggcc gggtcgaccg ggctggtcgt
    13741 acccttccgc ccgctggtgg aggccctgtc ctcgcacttc cgggcggcgg ggatccccac
    13801 cgaccccgaa ctggtcccgt accacccggc gttgtcccgc ctggtgcccg agtggagaaa
    13861 cggtacggcg tccggctgga cggagaccgt ggtcgagctc gccgaggctc tgctgcggct
    13921 gctgtccctg ctgggccgcg agaccggatg cgtgctcctc ctggaggatc tgcacgactg
    13981 cgacacggag accctcgcgg tcgtcgagta cctcgtggac aacctggcgg acctgccggt
    14041 cctgctgctc ggcaccctgc gccccgaccc cgtcaccgcg ctggacctcg cacgctccgc
    14101 cgagcagcgc cgcacggcgg tggtacggga gttgggcgcg ctcggggacg acgaggcgcg
    14161 ggcgctcgtc gccgcctgtc tggaggcgcc acccgagcag ttaccgccgg tggtcctgcg
    14221 aaggctggtg gagagggccg aggggagccc gtacctgatc gaggtgctgc tggccgacct
    14281 gctcgacacc ggccggctca gacgcaccga gaacggctgg gaggctgccg atctgccgga
    14341 cggcgggctc ccctcccgcg tccttcgggg ctgggcccgc aggctcgacc ggctggacga
    14401 accggtgcgg gacctgctgc tgacggcggc caccctgggc agccagttct ccgtgccggt
    14461 gctccagacg gtcaccggta tggaggaccg ggccctgttc acccatctgc ggtccgccgt
    14521 cgagatgggc gtgatcgcac ccgacggcgc ggcccccgac cgctacacgt tccggcacac
    14581 cctcaccgcg gaggccctga tctccacggt cgcgccggcc gagcgcgccg cactggcccg
    14641 ccgcgccgcc acggccgtcg agaactccgg tgtcccgctg gaggaggacc ggcgccagtt
    14701 gctggcgtcg ctggaactcg cggcgggcaa ccgcgcgggc gcggctgtgc ggttcgccga
    14761 ggcgggacgg cggatgctcg gagcggggtc gcacggttcg gccgtggtgc tgctggagcg
    14821 ggcccactca ctggccgccg acgccgaccg gtccgcggtc gccgagtcgc tggcggtggc
    14881 cagggccgag agcggggacc tggacggcgc cctggccctg gtcggcgcgc tgccgcccgt
    14941 ccccgcccgg tcacaggccg ctgcccggcg tggtgacgcc cacatcaaga tcgcctgggt
    15001 ggcggtgatg gcggagcggg ccgccgacac cgctggccag atcggcgccg cacgcgagct
    15061 gatcggcccg tcgccctccc ccgcgcggtg cgcgtcgctc gcggtggtcg acggccatct
    15121 ctcgttgctc ccgggagagg aggggcgcgg cgatcggaag gcggtcgagc gggcggccct
    15181 cgacgcggca cgtaccgccg aggccgaggg actgccggtg gtggcctgtc aggcctggca
    15241 gttgttggcg ctgctccgcc gggaggaggg gttcgacgcg gccgacatgt gcctggagcg
    15301 gatgctgacc ctggccaccg agcacggcct gccgctgtgg cgggtggagg ccctggtgcg
    15361 gctgggggcc aacggcttca tgcggacggg cgacgccgcc cggttgcgtt cggcgcggga
    15421 ggcggctgcg gagctgggtt cgctgctgct ggcccagacg gtcgacgccc tgctcgcgat
    15481 gaacgcggtc atgtgtgccc gctgggagga ggcggcggag gtcgtcgaac ggtcggtgga
    15541 ggtgagcgcc cgtatcggca acctggccgc gcaccgctac ctcctgctgg ccggggcgac
    15601 cacggccgtc caccgggggc gccggcggga ggccgagcgg tggctcaccg cgttccgccg
    15661 ggcgggcggc gagcagtcgc ctctggtgcc gctgcggctg ggcttctgcg gggccatcgg
    15721 ggcgctgctg gaggaggacc gggaccgcgc gcgggcggag ctggaggccg tgctcgcctg
    15781 ggaacgcgct cacccgagct actactacct gagcggccgg cacgggctgc gccccctgct
    15841 gcgggtactc gcgggcgagg cgggccgggc ggagtacgag gcggtggcgg cggcccccgg
    15901 ggccgcgctc gcctggaacc ggcagttcct ggacctggcg gaggcggtgc tgctgggccg
    15961 ggagggccaa ggggccgctg ccgaacggcg gatggcggcc ttcgacatcc ggtccgcggt
    16021 cttcccggtg gcccgccacc tcggtctgcg actggtcgcg gacgcggccc tcgccgacgg
    16081 gtggggggag ccggtgtcgt ggctgcgcgg cgccgaggag ttcttctacg acgccggggt
    16141 gcagccggtg gcggcggcct gccgggcggc cctgcggcag gccggcgtga gcgtgacgca
    16201 gcaccgcgac ggccgggacc ggatcccttc gccgctgcgc acccacgggg tgaccccccg
    16261 ggagtacgag gtgttcgtcc tgctggccga gcgcccgggc aaccagcaga tagcccgccg
    16321 gctgtccatc tcgccccgca cggtggagaa gcacctggcc agcctgctca gcaagacggg
    16381 ccgggcgaac cgggcggcac tgtgcgagtt cgccgcggag tgcctcgtcg accacgcctg
    16441 aggccacggg ccccgccctg gtgggggcgc accccggcaa catgggggca cggggcggtg
    16501 gaggtcgggt gcgccgcccg gaagatgcgg gccactcacc gatgtgcccc ggtacgcgga
    16561 ccggaaggat cggccggtgt acggaagccc gtcccccgtc cggtcggccg gggtgcggcg
    16621 gcccgttccc cgtccccctc cctggaggcc cgccgatgtc ccgacctgcc gcctgtcccg
    16681 gccccgccgg cgcggtgtac ttctcgctgc tcggcccgct caccgccgtg gtcgacggca
    16741 ggccgctgcc gctcggcccc cgcaagcagc ggctggtcct ggccaccctg ctgtcccggc
    16801 ccaacacccc cgtaccggtc gacgtgctga ccgacgtggt gtggccggac gcgccgccgc
    16861 ggaccgcccg caagaacctc caggtctacg tcagcgccgc ccgcacgctc ttcgcggccg
    16921 tggacggggg cgaccgggac cgggtggtgc acggctgcgg cggctaccgg ctgcggatcg
    16981 aggagggcga gctggacacc ctgcgctttc gcgcgctggc ccgggcgggc cgggcggccg
    17041 gtgagcgggg ggacctgcgc accgcggcgc ggctcctgcg ggaggcactg gatctctggg
    17101 gcgagcggcc gccgctgcac gatctgcgcg actccgacgt ggtggcccag gaggcggagc
    17161 ggctggaggc ccgctgcctg acggtctacg aggagtgggc tgaggccgag atcgagacgg
    17221 gccgggcggc cgtcgcggtg gacgggctgc gggacctggt ggagcgccac ccgctgcggg
    17281 agcggctgcg ggcggcctgg atgaactccc tgcaccagtc agggcgtcag tccgaggcgc
    17341 tggcggtgta cgacgactac cggcagttgc tggccaggga gctgggactg gagcccagtc
    17401 cggcgctggc cgccctctac gggagggttc tcggccgcgg ggcctcgccc cggccgtccg
    17461 cgggccgcaa ggcggcgtgc gacgtgtcgc tgcccgcgga cctccgggac ttcaccggcc
    17521 gcgaggacga gctggcgcgg ctgctgccgg tggcgggtgc cccggacggt ggtgtggccg
    17581 tcgtgaccgg tcccgccggg gtgggaaagt cggtgctggc cgtgcgggcg gcgcacctcc
    17641 tcggggaggg gttccccgac gggcggatcc atgtgcgggc ccgccgccag gacggcgcgg
    17701 cccgcacccg gaccgacctg ctggaggagc tggtacgcct gtgcggcgcg gacacgccgg
    17761 gccggccgga cgcggcggag gccgagaaca cctggcagga ctggctgtcc cggcaccggg
    17821 ccctggtcgt cctggacgac gtggtggacg aggcgtcggt acgcgggctg ctgccccgga
    17881 cgggacggag ctcggtggtc ctgaccgcac gggggcagct ggccggtctc gccccggtgc
    17941 accggatcgc cctgtgcgtg cccgaggacg gggaggccct ggacctgctg gagcggctga
    18001 tcgggccgga ccggctgcgc acggatcccg ccgccgccct gcggatcgta cgggcctgcg
    18061 gggcgctgcc gttggcggtc gcggtcagcg gtatgcggct ggcggtgctg cggcatctgc
    18121 cgctggcgga gtacgcggcg cgggtcgagg acccgggcgc ggccctggac gaactggtgg
    18181 ccggggacgt ctccgtacgg tcgcggatcg ccgcgggctg gcaggacctg agcgcccgtg
    18241 accgcacggc actggcccgg ctcgccgggc tctcgtcgga ctgcggcttc accctggagc
    18301 gggcgatggc ggcgctgcgc cgcgacgagc gggagaccat ccgcgccgtc gaggcgctca
    18361 tcggcaccgg ggcggtgacc tcgcccgccg gtgaggtcac cgcccatgcc gcctggtacg
    18421 aggtgccgcg cctgctctgc ctgtacgccc gcgagaccgc gggtcacgag gacgccgatg
    18481 cccccggggc atcccggggg ccggcgctcc agctcctcag ccgagggtga gcagttccag
    18541 cagaccggcg gggtcctgac cggccccgcc ctcgcccccg gacaggaagt gcaggccgag
    18601 cagcaccccg gccgcccccg aggcgaggtc ggcggagaag cgccgcagcg tcctgcccgg
    18661 gacgagcagc cggtccccgt cggcgaccag gtgccagggc aggttgcgta cggaggccag
    18721 gacgccgccc ccggtccggg gtcccggacc gagctgggcg gctgcggcga cgagccccgt
    18781 ccgcccggtg aacagccccg gttcgcggac gaactccatg acgcagccct tgcgtacacc
    18841 ggggatcagg gcgctcagtg cgggggccct gtgccgggtc tcgtacgcct gggacaccag
    18901 cgcgacgccc gagcttccct ggtcgaggta gagcaggtgg cgtcggccgt gtctcacctg
    18961 gagcgtgccg tccggcatgc ccacgatgtg tccggcctcc cgccccaggg cggtgcgcgc
    19021 ggcccggacg agccaggtct ccccggtcag cgtgtgcagt tccaggtcga gcagggccgc
    19081 accgctcagc ccgcgcagca gtcccgccga ctccgggagg cgcatcccgt ccaccgcctc
    19141 gccccgcacc agccggtcca ggtcgcgggc ggtgcgcagg gcttcgtcga tcagcttgcc
    19201 gtccaggtcc gtgccgccgg cccgggccat gcgcagggcg gccagcgcga tgcccgctcg
    19261 cccggtcagc aggtccgccg ccgtcggcgg tgcggcggac gccgcccggt cccacagctc
    19321 ccgcccctgc tcggcgcggc ccaggagcgt gagcaccacc gcggtgcccg gcagcccgtc
    19381 gaagaagccg cccgccccgg cggggtccct gcgcagcgcc gcccgggcga gccagtcggt
    19441 ccactcctcg gggacggggg cgcccacccg gtgcagggcg tacaggacac cggccgcgcc
    19501 gtgcgcgagg tcggtcccgc cgttggcgaa gagctccggg ccgcccggga agagacggtc
    19561 cgtccgcccg ggtgtggccc cggcgtggat cccggccagc agacgggcgc ggacccccgc
    19621 ccagtccacg tccggccctt cgaacagggc ggccacctcg gcctcgcgtc gccgtgaggc
    19681 gtccagcccg cgcagcagcg caggtcggcg tggtcccgcc ccggccggca gaccgtaccg
    19741 ccggcgggcc cagcgttcca gggtgagggc cttcgccctt tcgagtcctg ccatctccat
    19801 gaccggcatc agcatgccga gccaggtcgc ccagagcgcg taggcgtcgg cctccgcacc
    19861 gggggtgccg gggggcgcct ggaggccttg ggcaccggcc agcggggtgt cctcgtcgtc
    19921 gagcgcggtg gcgtactcga agtcgacgag ggcgatgcgc ccgtcgggcc ggacgatgac
    19981 gttggagggg tgcaggtcgc cgaagcgcag gccgcgcgcg tggatctcct ccagtgcccg
    20041 ggtgagctcg cccacgaccg agtcggtcca cgcgacgtag gtggccagtt cggccgcgga
    20101 gccctccccg cgtacgaggg agaagcgggc gacgatctcc tccagcagcg tgttcccctc
    20161 gatgtgttcc tcgatcagga agtggtgctc ccagacggtc cgtaccccgt acacctcggg
    20221 gacgcagtcc agcccggcca gcgtcgtcag cgcccggtgc tcgcggtgca gacgggtgac
    20281 ggcgtcgtcg cccgcgccgt cgaggccgca gtgcgggcgc gcctcccgca gcaccacgcg
    20341 gcggcccgtc tcccggtcca cggccagata gatcccgccg gcgttggaga actggagggc
    20401 ctcggtgacc gtgtagggga aggtgtcgtc gcgggcggcg gcgcgcgccg cgaggtgcgg
    20461 gcgcagggcc tcggggacct cgacccacgc gggtgtccgg aagaccaccc cgcgttcgtc
    20521 cggtacgagc gtcccggagg ggtcccgcag ggcgaggacc cggcggccgt cggcatcggt
    20581 gcaccagcgg gggacgaagg caccgtagcg ggtgtagacc ggggcgtcgc cgatccgcag
    20641 gtcgctgagg acgtaggggc cgctgcgccc cgccagcgcc tgggacagct ccccggcgag
    20701 cgtcaggaac acggtctcgt ccggcgggta gaccgcgatg aacttgcccg ccccgctgcg
    20761 gttcatgtac ttgtccgcca tcaccgacaa cgcccgccca ctgcgcagga atttgaacgg
    20821 cacgccgtgg cggacgcaga tgcgcgcggt gtcccgcagg gtgtcctcgg cctcgccggg
    20881 gacggtggac acatggatct tccagccctg ttcggccggt tcggcgtgct cgggcaccag
    20941 cgaggtccac aggccgacgg cctcgcggcg ccagccggcc gggggcgggt cggtgtcgag
    21001 ccggtaccgg gactcctcgt cgggcagccg ggccggggtc tcgaagtacg tacggtcggc
    21061 gaggcagtac atctgggttt cctgggtgcc tggcacgctc ggctctctct tctggaggcc
    21121 cgccacgggt gcggacggtg acggtggggc ggcgggggtc ccggtgcgcg ggtcagtccc
    21181 cggggacggc gtgccgcgcg ccggccgggg tgctcccggg gccgggctcc ggcgggtcgg
    21241 ctggctccgc ctcgtcgtgc ggggagggtt ccgcccgcgc cgacggggcg aaggtgacca
    21301 cgagggcgga cgcggccagc acgcaaccgg tcagggtgaa ggcccagcgg gcgccgaagg
    21361 cggtcagcag ggcaccaccg gccagcggcc cgaacggctg aacgagggag gagaggaagc
    21421 tcgccccgct ctgcacccgg cccacccggt cctcgggggt cacgatcagc agcgtcgaga
    21481 ggaagccgat gctggcgatc gtcgacaggc acatgcagag cgcgcacatg gccccggcgg
    21541 ccagtgggtt gcggagccac gccatcgtcc cggcggcagc cacacacgtc cagcaggtgg
    21601 cgaggatcag agcccgggag taccggtcgg ggttgatccg tggtgcgagc agcgctccgg
    21661 ccagcgctcc ggcggagacg caggtgatga cgaagccgcc accgacaccg gagcggcccc
    21721 cttcggagaa caccgagagc gcggtgaagg tgagcgcacc gaacgcgaag ttcatgccca
    21781 ggccgaagat cagaaggatc gtacgcagat aggggatagt ccacaaaaag ctcagccccg
    21841 cggtgagttc acgtcggctg aacaccggac ccgccgcggt ctcggcccgg gagcgggtac
    21901 gcacgagagc cacgcagacg gtggacagga gaaggcccag cgcctccgcc gcgaacggca
    21961 gagcagggtg gaggccgaac agagcgccac cgacgagcgg cccgaccagc cggaccgttt
    22021 gggtgcgggc ctgaagccgc gcggtggcgg tgcccatctg gtcggccggc acgaccgccc
    22081 gcatcaggcc gaagacggcc ggtccgtaga cgctgctgat caccgcgccc gctgccgcga
    22141 cgagcaggac gagcgccatg ggggcgtgcc cgaaccagac cgcggtggcg agtgcggtga
    22201 cgacgagcag actgccgacg tcgcacaacc gcatcagccg gcggcgctcg acgcggtccg
    22261 ccatgacacc gccggggagc atcgcgatca gcacggcacc cacggacacg gtgccgacgg
    22321 acccggcctg cacggcggag ccggtctcct tgagcaccaa cagggggagg gcgagggcac
    22381 tcatctgccc tcccaggacc gcgaagaggc cgctcatcca gagcagccgg aaatcccggt
    22441 tgtcgcgcaa cggggtggtc atcgataact cccggtggtc atcggatcgt ggcaggtggt
    22501 gcgggcggga cggccgccgg gccggaatcc gggtgccgtg gtcctgcgga acgcggagcc
    22561 cgggcgggac ggtccggaag cggcgacggg gcggtctccg tccacgacgg agccgcccca
    22621 ctcaccgacc ggccgggcac cgcgggggag gcctatgcct cggtccaccg cggcgccgac
    22681 ccggttcgtc cgatcagttg gcgttctcga cgacgctgac caggctcacg cagttgcccg
    22741 gcgcgatgac cttgtcgacg gccgtctcct ggaggtccag cacggagtgc gcctcgacct
    22801 cgggggtctc gttgttgtcg tcggccgcgg gcttggtgtt ctcggacatg gtggtctccg
    22861 tccactcgtg actgcgctgg ttccgggagg ccctgaggtg ccgggttccg gtggggcgag
    22921 ccgttgcccg ccgttgccga gaaagttagg aggccccgcc tgcgggacgc ttcggcggcg
    22981 gtatggcgcc ggtatcgcgc cagctcggcg gggatgtacg gcctcccggg ccgcccggcc
    23041 ccgtccggcc cggtccgggt gacctgcgcc cataccgccc ctgaagcggc cgtggaccgc
    23101 ctccgaaccg ccgcccgcca gcctgggtac gcacccgacg cgcaccggcc ctcgaaggag
    23161 gcggccccgc atggaactcg gcgaactcgt cggacggcgg ccgttccccg ccgccggcct
    23221 gctgctcgga ctgacccggc gctgccccct gagctgcgcc cactgctcga ccggatcgga
    23281 cccgaccgtg cgggaggcgc cggacgccgg ccgtctcgtg cgtttcgtcg gctcgttcac
    23341 ctcggagaac cgtcccgacg tggtgatgct gaccggcggt gaaccgctgc tgctgccggg
    23401 gctcgtcgag gagctgagcg cactcgcccg ccgggccgga tcgcgtaccg cgctgctcag
    23461 cggcatgttc ttcgcccgct cgcggcacat cccggccccg atcctgcggg cgatcaccgg
    23521 ggtcgaccac ttctcggcca gtctcgacgt ccaccacgag cgggaggtgg ggcgggccga
    23581 cgtcttccgt gccctgcacc gcatccggga ggcgggggtg gcggtgagct tccatctgac
    23641 cgggacggga gcctcggacc cctatctcgc ggacctcacc cgggacgtcg aggaggagtt
    23701 cggcggccag gtgccgtcgc tggtcaacga ggtgcggccg ttcgggcggg cggcgtcctg
    23761 ggccgggccc gcgcgcggca ccccggacgc gggcgcggcc tccccgtgct ccatggccgc
    23821 ctggccggtg gtcgccttcg acggcgcggt gctggcctgc tgcaaccagg acaccgtcga
    23881 cctgcggccc gcccccgccc atctgtacct cgggcacatc gccaccgacg actgggcggc
    23941 ggtacgccgg cgcgccctgg agtcgccggt gctgcgcatg atccgtacgg tcggccccgc
    24001 ccatctggcg gaccgctccg gcgtgccgcc ccggggcggc acctactgcg acggatgccg
    24061 ggccctgggc ggcgacgcac gggtggccgc cacggccggg gcggtggcgg ccggcgcggc
    24121 gggcgcgctg ctggacctgg ccgccgcccg gcggggcgcc gcccagggcc cggagggggt
    24181 cgtacgacgc cacggctgcg cggcgtacgc ccctctcgtc gtcgcggggg ctcccggagc
    24241 cggggccgtg ggcgggtccc ggtgagcgcc gcacggccga gcacctcggc gcggctgcgg
    24301 gtcaccttgg ggctgctgga cggcgagctg ctggcggcga tggagcacct gtggcgcccg
    24361 gaggacctgc tgccgcggta ccgcgcctat ctgtgcgcca tgcacacggt ggtgcgggcg
    24421 tccgtaccgc tgatgctgcg ggcccgggag cgcgcccggc tgctggacgc ctgcggtgat
    24481 ccggtggcgg gcccgctggc ggcctatctg accgagcaca tccgggagga ggagggccac
    24541 gacgcctggt tgctggacga cctgctggcc gcgggtgcca cgcccgggga cgcgctgcgg
    24601 ccgatgcccg agccggtcgt cgccgccctc gccggctccc agtactactg gatcgagcac
    24661 caccaccccg tcgcgctgct cggctacatc gcggtgctgg agggctacgc gcccgccgcg
    24721 accctgaccg cccgcatcgc caggacgacc ggactgccgg acgccgccct gcggaccgta
    24781 cgggagcacg cggcgctgga cacgggccat ctggacgacc tccacgcgct gctggaccgg
    24841 ctgccgctga ccgagggtca gcaggcggac gtgaccgtca gcgccatgca ctccctcgac
    24901 gcgctcgccc gtctgttcgt ccggctcggg cgctccggga cggcaccgcc gccccgggga
    24961 gccggacacc cctcaccgat gggagtctcc ccatgacccg accacccgag agcgacgacg
    25021 aacagccggt gctgcccgac gcgttgtacg aggccggcct gccggtggac ctgctcagcc
    25081 acgagcagcg tctcgtgctc agccggctga caccccagga gctgggcgtg ctgctcgaca
    25141 tcaagagccg gctggacgcg gtggaaccgg aagtccaggc acacggcgag atcgccggcg
    25201 gcgcgctgtt ctgagcagcg tccgcgcgcc ccggcccgcc tgtcccgggg cgcgcggggg
    25261 ggcccgaccc ctcggagaga aggaatcgtc atgacctgcc cctcgtgccg tcaggacctg
    25321 ccgccggacg cccggttctg ctcgtcctgc ggaacgccgt gcgccaccgc gcccgccccc
    25381 ggggacgacg aacgcaaacc ggtgacggtc ctcttctgcg atctcgtggg ctcgacggcg
    25441 ctgtcgggcg tactggaccc ggagaccctg cgtacggtca cgctgcggta cttcgaggcg
    25501 atgagcgacc ggatcgtggc cgagggcggc accccggaga agttcatcgg cgacgccgtg
    25561 atggcggtgt tcggcgtgcc cgtggtccgg gaggacgacg cccggcgggc gctggccgcg
    25621 gcgctcggga tgcgggacgc gctggccgag ctcaacgagg agctgcacgc ggcgctcggc
    25681 atccggctgg cgaccaggat cggcgtcaac accggccagg tggtggccgg tggcgacgcg
    25741 acggcccgcc aggccctggt gtcgggcgag accgtcaaca tcgcggcccg gctggagcag
    25801 aacgccgccg ccggcgagat cctcatcggc ccggacaccc tgctggcggc cggcccgacg
    25861 gtgtccgccg agcccaccgg gccgctccgg ctgaagggca agcaggacag tgtggaggcc
    25921 taccggctgc tcgccctggg caccgacgac ccggcccagc tgcgccgctt cgacgtcccc
    25981 ttcgtgggaa ggagcgccga gcaggaggcc ctggacgcgg cgctcgcgga caccgtgcgg
    26041 tgcggccgcg cggggctgct gcgggtcacc ggtgaggcgg gcgtcggcaa gacccggctg
    26101 gtccgggagt ggctggcgcg gcgttccgcc tcgggggaac tcgcctacgg cgcgggccgg
    26161 tgccgcagcc acggggagca gggcacgctc actccgctcg ccgacgccct gcgggccctg
    26221 ccggcgctcg ccggtgggcc ggtggacgcc tccggggcgg tggacgcctc cggggcggcg
    26281 gtcgaggacg acgcggcggc cctgctgtcg gcgggcctgc tgcgggacgg caccccgaac
    26341 gcgccgttcg aggacatgtg cgccgcgctg acgacggtcc tggcccgggc cgcccgggcc
    26401 cggccggtcg tggtggtcct ggacgacgcg cacgcggccg cgcccctgct gcttcggacg
    26461 ctggaccggc tgacggaggg ggcggggccc ccgggtgtgc tggtggtctg tgtgggccgc
    26521 ccggacggta cggccgacgg cgcgggcggg ctcccggtca ccgggctgcc ccccgaggaa
    26581 gccgcacggc tcgccgcgct gctggcccgg ctggacggcc gggacgggcc ggtggacgag
    26641 cgtctcctcg cccgtgccga gggcaatccg ctctacctgg agcaactgct cgtggacggg
    26701 cgggcggacg gcgtgggagc cggggggccg gacgccggtc tgccgccgac gctccaggcg
    26761 ctgctcggcg cccgaatcgg cgcgctggcc agggcggagc ggaccacggt cgatctcgcc
    26821 gccgtgatcg gccgcgagtt caccgcggcg gagctggtcc tgctggaggt gtccgcacgg
    26881 ctcgcggagc gaccgccgcc cgccgtggtg gccgtgccgt ccggggaacg ggcgcggcgg
    26941 ctggcgcgcg tcgaggaggt gctcgcggcg ctgggccggc gccggctggt ggagccggca
    27001 ccggcggggg acccggagac cgcggcgtac cggttcagca gcgggctggt gcacgaggtg
    27061 acgtacggct cgctgtccaa gcgggccaag gccgaccgtc acgcctgggc ggcggagctg
    27121 cccagtgtgc tgcgcgccgg ggacggcgcc gtcggcggac atctggagcg cgcctaccgc
    27181 taccgcgccg agctcgggct gctggacgag gcgaccgggc ggctgcgcgg ccgggcggcc
    27241 cgggcgctgg gccgggccgg ggcccaggcc gccgcccggt ccgacctgcc ctgggcgcac
    27301 agcctgctgg agcgggcggt cggcctcgac ccggacgacg cggcgtcggt gcgcaggctg
    27361 ggcgaggtgc gggtggccct cggggacacc gaggcgggga cggccctgct gcgccgggtg
    27421 cgggacctgg agtccgcgcc ggtggaggcc gcgcacgccc ggctggcgct cgtggtgctc
    27481 gaccccggcg gcccggggcc cggactcacc gcgacggccc gggcggtgct gccggtcttc
    27541 gaggccgccg gggactcggt gggccgggcc cgggcacatc tgcggctggc ccagcggctc
    27601 cagcaggcgg gccggcacga ggaggcggag cgcgaccagg cgcgggcgct ggagcaggcg
    27661 gtgctggccg gggccgaacc ggagcgcgcc ggggcgctcg gggccatcgg catctccctg
    27721 tggcgcggcc cggtgccggc gcccgatgcg gtggaacgct gccgtgccct gctcgcggcg
    27781 cacggcgggg gccgcccgac ggtccggctc accctgaact gtccgctggc ggtgctgtac
    27841 gcccttcagg accggccccg tgaggcgcac ggctgcctgg cggaggccga cgagctggcc
    27901 gaaaagctgc ggttcgccga ggcggaggtg ttcctgccgg tgttccgggc ggcggtggag
    27961 tcgctgctcg gccgcggccc ggtcgccctg gagctgctgg cccgcgccga cgcggcggcc
    28021 cggcacaccg gcgcggccgg gatgcggacg gccgtcgcgc tggacgcggc ccggatcgag
    28081 ctcgactcgg gccgtacgcg ccgggcggcc acccggctcg cgggcatcgg tgacgggacg
    28141 gagctgagcc acgccgacgc ggtcgacctg cgcgggatgc ggggccggct gtcggccgcc
    28201 gaagggcgcg cgttcgaggc ggtgggccac gcggaccggg cggtggcggc ctcgctgctc
    28261 acggactccc ccctggtcca ggcgacggcc gagctggacc gggcccgcac cctggacgcc
    28321 ctgggccggc gggcacaggc gcgggcctcc gcacggaccg cggcggcccg cttcgcggcc
    28381 aagggccatc tgccgggggt ccgccgggcc gcccgctgtg taccggagga gccggtgccg
    28441 gaggggaacg cgctcaccac gagggagagg agctgaccga tgggtgtcac cacgacgggc
    28501 acggcggcgg ggcaggggct gacctggagc ctgcgcgggc gcggccccga ggacgtaccg
    28561 gtgcccgccg acccgggacc gccgggcggc cggcccgcgc ggcgggcgac ggggcgcggg
    28621 gtgcgggtgt gcgtggtcga ttcgggcgtg gagcgcgacc atccgctggt cggcacggtg
    28681 gacggctcct gggtggtggt caaggacggg gagagcggtg cgatcaccgt ggagccgacc
    28741 acgaccggtg acacctgcgg gcacggcacg gcgtgcgcgg gcatcatccg ccgtaccgcc
    28801 cccgactgcg agatccacag cgtccgggtg ctcggcgagc gcttctcggg cacgggtgac
    28861 gtgctgatgg cggggctgcg ctgggcggtg gagcagcgct tcgacgtggt gaacctcagc
    28921 ctgtcgacca cccggacccg gttcgccccg gagctgcacc acctggccga ccgcgcctac
    28981 ttcgcccgta cggtgatcgt cgcctccgcg cacaacaccc cggtggagag cttcccgtgg
    29041 aggttcgcct cggtgatctc cgtcggcagc caccaggagg acgaccccga gctccatctg
    29101 tacaaccccg agcccccggt ggagttcttc gggccgggcc agaacgtgac ggtgccgtgg
    29161 ctgggcggcc ggaccatccg tacgaccggc aacagcttcg ccacgcccta cgtcgccggg
    29221 ctctgcgccc gggtcctctc cgcgcacccc agcatgacgg cctttcagct caagaacgcc
    29281 ctctatctgt ccgcggccaa cgtgcacgcg ggcccgcgtc cttccacagc ggcaggagac
    29341 atccgtgacg actccgagaa ctgacatgac gctcaccccc tcccccgccc cgggcgacgc
    29401 ggcccggcgc gaactgctcc agtcggtcgt cgacgtcgcc cgcgcgatct tcggggccgc
    29461 ggccagctcc gtcttcctgc tcgacgagga ggcggacgag ctggtcttcc aggcggtctc
    29521 cggggagggc gaggagttcc tggtgggacg gcgcttcccg gccgggcggg gcatcgcggg
    29581 ctgggtggtg acctccggcg agccgatggt ggtggacgac ctgagcagcg acgcgtcctt
    29641 cgaccgcgcc ctggcggagt ccacggcgta cgtccccgac gcgatcatgg cggccccgct
    29701 gatcagcgac tcccgggtgc tgggggtcct ggaggtgctg gacccgtcgc cgcaggcgcg
    29761 gtcgggcgtc cgcgagctgg acctgctggc gatgttcgct cggcaggcgg ccgccgcgct
    29821 gcgggtcctc gccccggcac cggccggggt gccggaagcc gggcgcaccc tggacggcgc
    29881 ccgccgggag gacgccctgg agctgctcgg cagtctggaa cggctgttgc ggggcacggg
    29941 ctgaggagac gatacgtacg ctgggccgcg cgggagtgac gtcccgcgcc caccggcccg
    30001 tgcaggacgg aaggactcgc cgtgaagctc gctttctcga ccctcggagt gccggggatg
    30061 tccgtgaccg aggtggtgcg cctcgccgcc gcgaacggat accagggggt ggagctgcgc
    30121 gcccaccccg aggagccggt gcacccgggc ctcaccccgc tcgaacgggg ctcggtggcc
    30181 gaggagttca agcggggcgg ggtggaggtc ctgaccgtcg ccggatacgc cagggtcgcc
    30241 gccgagggcg acgacgaacc ggtgctggcc gagctcgccg ggctggtgga gctggcccgc
    30301 gacctgggcg cgccgtacgt ccgggtgttc cccggcggcg ggggcctgga cccggacgag
    30361 gcggacgcga ccgccgcccg gcggctgggc gcggccgctc cgcacgccgc cgacctgggc
    30421 gtacggatcc tgctggagac ccatgactcg caccgcgccg gggccgacgt ggcccgggtg
    30481 gtgggcacgg tggggcacgg gtcgatcggg gcgatctggg acgtgatgca cacctggctg
    30541 gccggcgagg aggcaccggc cagccacgcg gtgctcgccc cgcacctggg ctacgtccag
    30601 gtcaaggaca tcgcctcggt cgaggacacc accccgctcg ccctcggagc cggggtgctg
    30661 ccgctgcgga cgtgtctgga cgggctggac cccgacgcct gggtctgctg ggagtacgag
    30721 aagcgctggt acccggaggc ggcggagctg ccggggctgc tggccgaggg acgggagtac
    30781 ctgctgcggc tgggcgcgcc gaagcagtag cgcggccccg cgccccctcg gccacgggga
    30841 gcggcggtgc ggcggcgggg cgcggccggg ccagggaggt cagggccacc ccgccgacca
    30901 gcagcagcgc cgcgcaccat cgcagcaggc tcaccggctc gcccaggacg agggccgccg
    30961 aggacatccc gaagacgggc accagcagcg tgaacggggc gacggacgag gccgggtggt
    31021 ggcggagcag gaagccccag gccccgaagc cgaagacggt ggagacccag gcgacgtaga
    31081 ggagtgtccc ggcgcc
//
