LOCUS       NC_015953              21035 bp    DNA     linear   CON 08-MAY-2024
DEFINITION  Streptomyces sp. SirexAA-E, complete sequence.
ACCESSION   NC_015953
VERSION     NC_015953.1
KEYWORDS    GSC:MIGS:2.1; RefSeq.
SOURCE      Streptomyces sp. SirexAA-E
  ORGANISM  Streptomyces sp. SirexAA-E
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7414440)
  AUTHORS   Takasuka,T.E., Acheson,J.F., Bianchetti,C.M., Prom,B.M.,
            Bergeman,L.F., Book,A.J., Currie,C.R. and Fox,B.G.
  TITLE     Biochemical properties and atomic resolution structure of a
            proteolytically processed beta-mannanase from cellulolytic
            Streptomyces sp. SirexAA-E
  JOURNAL   PLoS One 9 (4), e94166 (2014)
   PUBMED   24710170
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Complete sequence of Streptomyces sp. SirexAA-E
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 7414440)
  AUTHORS   Lucas,S., Han,J., Lapidus,A., Cheng,J.-F., Goodwin,L., Pitluck,S.,
            Peters,L., Ovchinnikova,G., Davenport,K., Detter,J.C., Han,C.,
            Tapia,R., Land,M., Hauser,L., Kyrpides,N., Ivanova,N., Pagani,I.,
            Adams,A., Raffa,K., Adams,S., Book,A., Currie,C. and Woyke,T.
  CONSRTM   US DOE Joint Genome Institute
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2011) US DOE Joint Genome Institute, 2800 Mitchell
            Drive B310, Walnut Creek, CA 94598-1698, USA
COMMENT     ##MIGS-Data-START##
            investigation_type                :: bacteria_archaea
            project_name                      :: Streptomyces sp. SirexAA-E
            collection_date                   :: Missing
            lat_lon                           :: Missing
            depth                             :: Missing
            alt_elev                          :: Missing
            country                           :: Missing
            environment                       :: Soil, Terrestrial
            num_replicons                     :: 1
            ref_biomaterial                   :: Missing
            biotic_relationship               :: Free living
            trophic_level                     :: Missing
            rel_to_oxygen                     :: Aerobe
            isol_growth_condt                 :: Missing
            sequencing_meth                   :: WGS
            assembly                          :: Newbler v. 2.3 (pre-release)
            finishing_strategy                :: Finished
            GOLD Stamp ID                     :: Gi05895
            Funding Program                   :: DOE-GLBRC 2008
            Source of Isolate :: Cameron Currie (currie@bact.wisc.edu)
            Cell Shape                        :: Filament-shaped
            Motility                          :: Nonmotile
            Sporulation                       :: Sporulating
            Temperature Range                 :: Mesophile
            Gram Staining                     :: Gram+
            Diseases                          :: None
            ##MIGS-Data-END##
            ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Finished
            Current Finishing Status          :: Finished
            Assembly Method                   :: Newbler v. 2.3
            Genome Coverage                   :: 30x
            Sequencing Technology             :: 454/Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000177195.2-RS_2024_05_08
            Annotation Date                   :: 05/08/2024 02:12:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,619
            CDSs (total)                      :: 6,532
            Genes (coding)                    :: 6,385
            CDSs (with protein)               :: 6,385
            Genes (RNA)                       :: 87
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 147
            CDSs (without protein)            :: 147
            Pseudo Genes (ambiguous residues) :: 0 of 147
            Pseudo Genes (frameshifted)       :: 61 of 147
            Pseudo Genes (incomplete)         :: 120 of 147
            Pseudo Genes (internal stop)      :: 8 of 147
            Pseudo Genes (multiple problems)  :: 39 of 147
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 989126
            Orig. end                         :: 1010161
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP002993.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 4086644
            Source DNA and organism available from Cameron Currie
            (currie@bact.wisc.edu)
            Contacts: Cameron Currie (currie@bact.wisc.edu)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-LANL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. it is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21035
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21035
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21035
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11035](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11035
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            33..884
                     /locus_tag="SACTE_RS04185"
                     /old_locus_tag="SACTE_0864"
     CDS             33..884
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044784.1"
                     /locus_tag="SACTE_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0864"
                     /product="metallophosphoesterase"
                     /protein_id="WP_014044784.1"
                     /transl_table=11
                     /translation="MADGSGQLLAISDLHISHAENRAFVERMAPDSEDDWLIVAGDVSE
                     TVDDIRWALKTLAGRFRKVVWAPGNHELWTHPRDAVTLRGTARYEYLVEMCRELGVVTP
                     EDPYPVWDGPGGPVAVAPLFLLYDYTFLPAGCATKDEGLAYAHRTGVVCTDEYLLHPDP
                     YPSREAWCRDRVALTEQRLAALPEDMPTVLVNHYPLDRHPMEVLWYPEFAMWCGTRLTA
                     DWHRRFRVAAMVYGHLHIPRTTRHEGVRFEEVSVGYPREWRKRPGTPGRPRRILPVEGQ
                     DR"
     gene            881..1561
                     /locus_tag="SACTE_RS04190"
                     /old_locus_tag="SACTE_0865"
     CDS             881..1561
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (103-166). E-value: 2.8e-21. Score:
                     67.8. Matches aSDomain:
                     nrpspksdomains_SACTE_RS04190_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044785.1"
                     /locus_tag="SACTE_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0865"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_014044785.1"
                     /transl_table=11
                     /translation="MIEELFPDSVVAVESYGDDGADQAPLHPGEEAVVARSVDKRRREF
                     TAVRTCARRAMEKLGVPPQPVLPGERGAPRWPDGLRGSMTHCDGYRAAALVRATDLASL
                     GIDAEPHGPLPEGVLRSVALPVEQERLALLATRLPAVHWDRLLFSAKESVYKAWFPLTG
                     MWLGFEEADIEIHPDPGTEPCGRFRARLLVPGPVVGARRLGHFDGRWIVRQGLVTTAVT
                     VHHT"
     aSDomain        1190..1378
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SACTE_RS04190_ACPS.1"
                     /evalue="2.80E-21"
                     /label="SACTE_RS04190_ACPS.1"
                     /locus_tag="SACTE_RS04190"
                     /protein_end="166"
                     /protein_start="103"
                     /score="67.8"
                     /tool="antismash"
                     /translation="LGIDAEPHGPLPEGVLRSVALPVEQERLALLATRLPAVHWDRLLF
                     SAKESVYKAWFPLTGMWL"
     gene            complement(1689..2120)
                     /locus_tag="SACTE_RS04195"
                     /old_locus_tag="SACTE_0866"
     CDS             complement(1689..2120)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044786.1"
                     /locus_tag="SACTE_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0866"
                     /product="cold shock domain-containing protein"
                     /protein_id="WP_014044786.1"
                     /transl_table=11
                     /translation="MAAGRVIRFDGMRGYGFIAPEHGGEDVFMHVNDLLIPESAVRAGL
                     MVEFEIEDGDRGLKASEVRLASEAEGLTGVPPVPRTPVAPAPFTEGQEPMCDVLSSAEY
                     LREVTELLLTAAPDMTGHQIKAVRKQFALLGTRHGWIED"
     gene            2319..3029
                     /locus_tag="SACTE_RS04200"
                     /old_locus_tag="SACTE_0867"
     CDS             2319..3029
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123149.1"
                     /locus_tag="SACTE_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0867"
                     /product="DUF5995 family protein"
                     /protein_id="WP_014044787.1"
                     /transl_table=11
                     /translation="MDRFEQCAVPAVPGGPAADVGTVIARMRAYRSRWPPQDGVAVFNQ
                     VYLTVTEAVGGRIADGSFADPQAVSVLDVRFAELYLTAVETEASGGRAPDCWRALFAYR
                     RHPGVRPLQFALAGINAHIGHDLALAVVDTCRALDCAPEDLEGEFRRVGDLLVTLEEEI
                     REDLMPGPDLLEIADPLTHLASTWSLERAREASWAAARVLWRLRGVPPLAEEFRTRMDA
                     GVGLVGRLLLTPCR"
     gene            complement(3070..4761)
                     /locus_tag="SACTE_RS04205"
                     /old_locus_tag="SACTE_0868"
     CDS             complement(3070..4761)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671499.1"
                     /locus_tag="SACTE_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0868"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_014044788.1"
                     /transl_table=11
                     /translation="MTSTVPNAVQHTDAQPPITMFGPDFPYAYDDFLAHPAGIGQVPAT
                     EHGAEVAVVGGGLSGIITAYELMKMGLKPVVYEADRIGGRLRTVGFEGCDPSLTAEMGA
                     MRFPPSSTALQHYIDLVDLETRPFPNPLAPATPSTVVDLKGESHYARTIDDLPQVYRDV
                     AAAWNTCLEEGADFSDMNRAMRERDVPRIREIWSKLVEKLDNQTFYGFLCASDAFTSFR
                     HREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDHHRGIVGGSQQLPLRLWDREPQK
                     ITHWPLGTSLSSLHGGEPRPAVTRLDRTAGNRITVTDAAGDIRSYRAVVFTGQSWLLLS
                     KIACDDALFPIDHWTAMERTHYMESSKLFVPVDRPFWLDKDETTGRDTMSMTLTDRMTR
                     GTYLLDDGPDRPAVICLSYTWCDDSLKWLPLSPNERMEVMLKSLGEIYPGVDIRSHVIG
                     NPVTVSWENEPYFMGAFKANLPGHYRYQRRLFTHFMQDRLPADKRGLFLAGDDISWTAG
                     WAEGAVQTALNAVWGVMHQFGGGTDPSNPGPGDVFDEIAPVELPED"
     gene            complement(4841..5638)
                     /locus_tag="SACTE_RS04210"
                     /old_locus_tag="SACTE_0869"
     CDS             complement(4841..5638)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453202.1"
                     /locus_tag="SACTE_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0869"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_014044789.1"
                     /transl_table=11
                     /translation="MPSLRTALLQSSGRPGFVEHNLGLIDEAAGRAAAAGARLLVCSEL
                     FLTGYALGDDLPSLAEPADGPSAQAVSELCARHGIAVLYGYPERSGELVFNATRLVGPD
                     GTALADYRKTHLFGPFEQRWFTPGDRPVVQAELDGVRIGLLICYDVEFPENVRAHALAG
                     TGLLLVPTALMHPYPFVAESVVPVRAFENQMYIAYVNRTGPEGEFEFIGLSCLAGPDGT
                     ARVRAGRGEELLVGDVDPGLLDASRTANPYLRDRRPALYGALA"
     gene            5743..6087
                     /locus_tag="SACTE_RS34855"
     CDS             5743..6087
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SACTE_RS34855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_019993686.1"
                     /transl_table=11
                     /translation="MREKALWRRFVARRVVAGQKGDLGRCPPTASPTSATAATTRTYST
                     ALDPYPGRFVVHGPPAAVLEGGRPGGMVLIEGVGPGYGPAGRAEKLRAETEGSAAPPRT
                     DLPQAGGPWE"
     gene            complement(6063..6518)
                     /locus_tag="SACTE_RS04220"
                     /old_locus_tag="SACTE_0870"
     CDS             complement(6063..6518)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512479.1"
                     /locus_tag="SACTE_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0870"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_019993685.1"
                     /transl_table=11
                     /translation="MRLNDLDERIVHALAEDARRSYADIGALVGLSAPAVKRRVDRLRA
                     EGAITGFTVRVDPAALGWQTEGFIEIYCSRNTAPEAIKQGLARFPEVASASTVTGEADA
                     VVQVFAADMRHFEQVLERIAGEPYIERTKSVLVLSPLLRRYSQGPPA"
     misc_feature    6485..6499
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.18"
                     /tool="antismash"
     gene            complement(6616..8076)
                     /locus_tag="SACTE_RS04225"
                     /old_locus_tag="SACTE_0871"
     CDS             complement(6616..8076)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576365.1"
                     /locus_tag="SACTE_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0871"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_014044791.1"
                     /sec_met_domain="Aldedh (E-value: 1.5e-157, bitscore:
                     523.4, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSFFTDLALQYVDGEWRPGKGSWDIIDFNPYDGEKLASITVATA
                     GEVDQAYRAAERAQRGWADTNAYERRAVMEKALRVVEEREAEIAEAIVAELGGTRLKAA
                     FELHLAKEFLREAVQLALRPTGEILPSPVEGKENRVHRVPVGVVGVISPFNFPFLLSLK
                     SVAPALALGNAVVLKPHQNTPVCGGTLLAKVFEEAGLPAGLLNVVVTDIAEIGDALLEH
                     PVPQLISFTGSDKVGRHVATVCAAHLKRAVLELGGNSALIVLDDADIDYAVDAAVFSRY
                     VHQGQVCMAANRILVDRAVEEEFTEKFVAKVASLRVGDPADPATHIGPLINSSQADAVS
                     KIVDRTVEEGATALLHGRADGNLVSPSVLTGIPAGSPVLHEEIFGPVALLVPFDGEDEA
                     VRIANDTPYGLSGAVHTGNIERGVRVGRRIHTGMIHINDGTVHDEPVVPFGGEKNSGLG
                     RLNGDATLEAFTTQKWISVQYGRSRFPF"
     misc_feature    8070..8083
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(8070..8084)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.59"
                     /tool="antismash"
     misc_feature    complement(8116..8129)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.48"
                     /tool="antismash"
     misc_feature    8117..8130
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.26"
                     /tool="antismash"
     misc_feature    complement(8117..8132)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.13"
                     /tool="antismash"
     misc_feature    8118..8131
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.46"
                     /tool="antismash"
     misc_feature    complement(8119..8132)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.26"
                     /tool="antismash"
     misc_feature    8146..8160
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            complement(8239..9705)
                     /locus_tag="SACTE_RS04230"
                     /old_locus_tag="SACTE_0872"
     CDS             complement(8239..9705)
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103924.1"
                     /locus_tag="SACTE_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0872"
                     /product="GuaB1 family IMP dehydrogenase-related protein"
                     /protein_id="WP_019993684.1"
                     /transl_table=11
                     /translation="MRFLEPGTGRHTASPSVPYDLTYDDVFMVPGRSAVGSRQAVDLSS
                     PDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDIPLEVVTEVIGWVKKRHLVL
                     DTPIVLAPGQTVADALSLLHKRAHGAGIVVDSENRPVGVVTDHDLSGVDRFTQLSEVMS
                     KDLVVLDAGIEPRDAFNTLDGANRKLAPAVDADGRLVGILTRKAALRATLYTPATDDAG
                     RLRIAAAVGINGDVAGKARQLLDAGVDTLVVDTAHGHQESMLGAVAAVRALDPGVPLVA
                     GNVVAAEGVRDLVEAGADIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEARRHGKH
                     VWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQSADGRYYKESFGMASAR
                     AVRNRTSEESAYDRARKGLFEEGISTSRMFLDPARPGVEDLIDSIIAGVRSSCTYAGAG
                     SLEEFAEKAVVGVQSAAGYAEGKPLHASWN"
     misc_feature    complement(9695..9709)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    9696..9707
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.23"
                     /tool="antismash"
     misc_feature    9705..9719
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.9"
                     /tool="antismash"
     misc_feature    9712..9721
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9713..9726
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.76"
                     /tool="antismash"
     misc_feature    complement(9714..9727)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.18"
                     /tool="antismash"
     misc_feature    9715..9728
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    9716..9729
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.7"
                     /tool="antismash"
     gene            10001..11035
                     /locus_tag="SACTE_RS04235"
                     /old_locus_tag="SACTE_0873"
     CDS             10001..11035
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044793.1"
                     /locus_tag="SACTE_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0873"
                     /product="terpene cyclase"
                     /protein_id="WP_014044793.1"
                     /sec_met_domain="T1TS (E-value: 4.5e-85, bitscore: 285.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESELPDIYCPFPQRSNPHVAATRAHLDTWTRSTGLVHRDSARQR
                     FEQADFGAFVGMVHPTAGSEHLDLVADWFVWLFLVDDQLDDGHLGRSPERVRDVVARMR
                     AVVEGVAPHPLPGEEPPAAVVALCDLWERTVPRAAPHWRTRFTWHLMTYLTTATTWEAG
                     NRAGGVVPSEATYIAKRRHTGAIHVCMDLIEIVAGIEAPESLHNDPRFITALEASCNVV
                     CWANDVYSYEKEQVLGEIHNLVHLVRHHRGYGEQRALDHVCAEIAAETERFLTAEDELI
                     DMYPQLTDLLVPYLDGMRSWMRGNLDWSRQTPRYNPAAVSQYTAPGEYLEETVLGVATD
                     SAGH"
     gene            complement(11125..12117)
                     /locus_tag="SACTE_RS04240"
                     /old_locus_tag="SACTE_0874"
     CDS             complement(11125..12117)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157400.1"
                     /locus_tag="SACTE_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0874"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_050986357.1"
                     /transl_table=11
                     /translation="MRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLET
                     ALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPAEEQDDAADPENLGEVAAD
                     LLGELVNEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGVYDAGTAERGSVEAVRRAA
                     QVSGGEAHPIYAPMLLPDPATAAALRHQTGIARAFEYFDKVTVAAVSIGSWEPGISTVH
                     DMLSDEERAHYASLGVAAEMSAHLFDSDGRRVGRDLGERCITVEADRLRRIPEVVAIAG
                     GQRKAAAIGAVLRSGLVTSLVTDTAAADYLLTESAAGQRPALERADPDD"
     gene            complement(12249..12932)
                     /gene="rpe"
                     /locus_tag="SACTE_RS04245"
                     /old_locus_tag="SACTE_0875"
     CDS             complement(12249..12932)
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044795.1"
                     /locus_tag="SACTE_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0875"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_014044795.1"
                     /transl_table=11
                     /translation="MAQINPSILSADFARLAEEAKAVEGADWLHVDVMDNHFVPNLTLG
                     VPVVEALSKATDTPLDCHLMIEDADRWAPQYVEAGAGSVTFHVEAAAAPVRLAREIRAK
                     GARASMALKPATPVEPYEDLLPELDMLLIMTVEPGFGGQAFLDIMLPKIRRTRELISKH
                     GLELWLQVDGGVSASTIERCAEAGADVFVAGSAVYGAQDPADAVRALRARADAATAGAT
                     WACGH"
     misc_feature    complement(12919..12932)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            complement(13054..14487)
                     /locus_tag="SACTE_RS04250"
                     /old_locus_tag="SACTE_0876"
     CDS             complement(13054..14487)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551353.1"
                     /locus_tag="SACTE_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0876"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_014044796.1"
                     /transl_table=11
                     /translation="MNDQQRRRPAKQHRRPEKDPVRFLAFEALRAVDERDAYANLVLPP
                     LLKKARAKGDFDGRDAALATELVYGTLRRQGTYDAIVAACVDRPLREVDPPVLDVIEMG
                     VHQLLGTRIPTHAAVSASVELARVVLGEGRAKFVNAVLRKVSAHDLDGWLERVAPAYDE
                     DAEEHLSVVHSHPRWVVSALWDALGGGRAGIEDLLEADNERPEVTLVARPGRSTTDELL
                     AALGEESGLAGRWSPYAVRMAEGGEPGALTAVQEGRAGVQDEGSQLVAAALAQAPVEGR
                     DSRWLDGCAGPGGKAALLGALAAARGATLLAAEKQPHRARLVERALAGNPGPHQVITAD
                     GTRPPWRPGSFDRVLMDVPCSGLGALRRRPEARWRRRPQDLESFAPLQRGLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGASAEAEWVDARPLLPGVPALGDGPDIQL
                     WPHLHGTDAMYLALLRRTA"
     gene            complement(14571..15503)
                     /gene="fmt"
                     /locus_tag="SACTE_RS04255"
                     /old_locus_tag="SACTE_0877"
     CDS             complement(14571..15503)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490197.1"
                     /locus_tag="SACTE_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0877"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_014044797.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASERHEVAAVVTRPDAPAGRGRRLV
                     ASPVAERAEEAGIEILKPARPRDEDFLARLREIAPDCCPVVAYGALLPKSALEVPARGW
                     VNLHFSLLPAWRGAAPVQHSVMAGDEVTGASTFLIEEGLDSGPVYGVLTEEVRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDGTLHAVPQPAEGITLAPKITVEDAQVRWAEPALRVD
                     RVVRGCTPAPGAWTLFRGERLKLVQAVPVPDRTDLAPGELSAGKNNVYVGTGSYAVELL
                     WVQPQGKKPMRAADWARGVRIAHGELLGA"
     gene            15736..16290
                     /locus_tag="SACTE_RS04260"
                     /old_locus_tag="SACTE_0878"
     CDS             15736..16290
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057355.1"
                     /locus_tag="SACTE_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0878"
                     /product="hypothetical protein"
                     /protein_id="WP_014044798.1"
                     /transl_table=11
                     /translation="MADHATHDAQARASLHLLVRDIERVRRQVDALRTLTAQLGNVYRP
                     RRSGPSAGFVVYGRAPAPTVRLAQELRDSVETLVTAAVDFDRSLGFSWDAVGSALGVTK
                     QAVHRRYGSRRTTAQSAAGEAAETAARKQPAPAGTSAALPVVPAARSMPPQPSPGPASP
                     TDRAAPREELRPGAFPGPRNG"
     gene            complement(16350..18494)
                     /locus_tag="SACTE_RS04265"
                     /old_locus_tag="SACTE_0879"
     CDS             complement(16350..18494)
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044799.1"
                     /locus_tag="SACTE_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0879"
                     /product="primosomal protein N'"
                     /protein_id="WP_014044799.1"
                     /transl_table=11
                     /translation="MSSDNERSEEPDAGAPEQLALIRETVRRAKVPRAKPRTWRGAALA
                     EELPVARVLVNKGALHLDQYFDYAVPEELDADAQPGVRVRVRFGAGGRQVRGGRREGGG
                     LIDGFLVERRASSDYQGALAALAYVVSPEPVLGPELLALCRAVADRYAGSLADVLQLAV
                     PPRNGRAESKASPAPLPPPPVPSPGTWERYTQGPGFLRALAEGGAPRAVWTALPGPHWP
                     EEIARAVAATLASGRGALVVVPDGRAAGRVDAALTALLGKGHHALLTADSGPEKRYGQW
                     LAVRRGSVRAVVGTRAAMFAPVADPGLVAVWDDGDSSHSDDNAPFPHVREVLELRAAHG
                     RCGFLLGGINCTVEAAQLVESGWALPLRAERERLRSAAPLVRTVDDGELARDGAARSAR
                     LPSLAWQTVRDGLRGGPVLVQVPRRGYAPRLACERCREPARCRHCAGPLQATDRQDLDC
                     AWCGRAETAWRCGACGGVRLRAQIVGARRTAEELGRAFPAVPVRTSGRDHVLDSVPDQP
                     ALVVSTPGAEPVAEGGYAAALLLDGWAMVGRPDLRAGEEALRRWTAAAALVRGRSEGGT
                     VVVVAEPTLRPVQALVRWDPVGHARRELAERAELGFPPVSRMASVTGPPEALAAFLATA
                     ELPAQAEVLGPVPVPATAAGRPRRPGDAPPGEVWERALIRVPPGRGAALAHALKAASAA
                     RTARGSGDPVRIRIDPPDIG"
     gene            complement(18627..19835)
                     /gene="metK"
                     /locus_tag="SACTE_RS04270"
                     /old_locus_tag="SACTE_0880"
     CDS             complement(18627..19835)
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="SACTE_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SACTE_0880"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_014044800.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTILDALLREDPSSRVAVETL
                     ITTGLVHVAGEVTTKAYADIPNLVRSKVLEIGYDSSKKGFDGASCGVSVSIGAQSPDIA
                     QGVDTAYEKRVEGDEDELDKQGAGDQGLMFGYACDETPELMPLPIHLAHRLSRRLSEVR
                     KNGTIPYLRPDGKTQVTIEYDGDKALRLDTVVVSSQHASDIDLDSLLAPDIREFVVEHV
                     LNQLVEDGIKLDTEGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGMARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLAARCEVQVAYAIGKAEPVGLFVETFGTAAVDT
                     EKIEHAIGEVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRELPDFTWERTDRVDALRTA
                     AGL"
ORIGIN
        1 ggtcaggagc gtgcgggggc gggggagatc gagtggccga cggtagcggg cagttgctgg
       61 ccatcagcga cctgcacatc agccacgcgg agaaccgcgc cttcgtcgag cgcatggcgc
      121 cggactccga ggacgactgg ctgatcgtcg ccggggacgt ctccgagacc gtggacgaca
      181 tccgatgggc cctcaagacg ctggccggcc gcttccgcaa ggtcgtctgg gctcccggca
      241 accacgagct ctggacccac ccgcgcgacg ccgtcaccct ccgcggcacc gcccgctacg
      301 agtacctggt cgagatgtgc cgcgagctcg gcgtggtcac gcccgaggac ccctacccgg
      361 tctgggacgg ccccggcggc ccggtcgccg tggctccgct cttcctgctg tacgactaca
      421 ccttcctgcc ggccggctgc gccaccaagg acgaggggct cgcctacgcg cacaggacgg
      481 gcgtcgtctg caccgacgag tacctgctcc acccggatcc ctacccgagc cgcgaggcct
      541 ggtgccgtga ccgggtggcc ctgaccgagc agcggctcgc cgcgctcccc gaggacatgc
      601 cgacggtcct cgtcaaccac tatccgctgg accgccatcc catggaagtc ctgtggtacc
      661 cggagttcgc catgtggtgc ggcacccggc tcaccgccga ctggcaccgc cggttccggg
      721 tggccgccat ggtctacggc catctccaca tcccgcgtac gacccggcac gagggcgtcc
      781 gcttcgaaga ggtgtcggtg ggctatcccc gtgagtggcg caagcgcccg gggacgcccg
      841 gcagaccgcg ccgcatcctg ccggtggaag gacaggacag gtgatcgagg aactgttccc
      901 ggactccgtg gtggccgtgg agtcctacgg ggacgacggg gccgaccagg caccgctcca
      961 ccccggggag gaggcggtgg tggcccggtc ggtggacaag cgccgccgcg agttcaccgc
     1021 tgtgcgcacc tgcgcccgcc gcgccatgga gaagctcggt gtgccgcccc agcccgtcct
     1081 gcctggtgag cgcggcgcgc cgcgctggcc ggacggtctg cgcggcagta tgacccactg
     1141 cgacggctac cgtgccgccg ccctggtccg cgccaccgat ctggcctcgc tcggcatcga
     1201 cgccgagccc cacggtccgc tcccggaggg ggtcctgcgc agtgtcgcgc tccccgtcga
     1261 gcaggagcgg ctggccctgc tcgccacccg cctgcccgcc gtccactggg accggctgct
     1321 gttcagtgcg aaggagtccg tctacaaggc gtggttccct ctgacgggga tgtggctggg
     1381 cttcgaggag gccgacatcg agatccaccc ggatcccggc acggagccgt gcggccgctt
     1441 ccgcgcccgg ctgctcgtcc cggggccggt ggtgggcgcc cggcgcctcg gtcacttcga
     1501 cggccggtgg atcgtccgcc agggcctggt caccaccgcg gtgacggtcc accacacctg
     1561 atcaccgccc cgcgggaccg gtacggacgt gccgaacgaa cggccgaggc ggggccgccg
     1621 gacggccgcg cccgtcgaag ggagtcacgc gaccgccgaa gcgctccccc ggggccgcgc
     1681 ccgtgccgtc agtcctcgat ccacccgtgc cgggtgccga gcagcgcgaa ctgcttgcgc
     1741 accgctttga tctgatggcc cgtcatgtcc ggggcggcgg tcagcagcag ctcggtcacc
     1801 tcacggaggt actccgccga gctgagcacg tcgcacatcg gctcctggcc ctccgtgaag
     1861 ggagcggggg ccaccggggt ccgcgggacc ggcgggacgc ccgtcaggcc ctcggcctca
     1921 gaggccagcc gcacctcgga cgccttgagc cctcggtcgc cgtcctcgat ctcgaactcc
     1981 accatgagcc cggcgcgcac cgccgactcg gggatgagca gatcgttcac gtgcatgaag
     2041 acgtcttccc caccgtgctc cggcgcgatg aacccgtacc cacgcattcc gtcgaaacgg
     2101 atcacccgac ctgcagccat ccccagccct cactactcgc acacccgccc ggcgtttggc
     2161 cccgatcgta atcacatccc tccccgaggt cacggccgcg gcgggctcga cgccaccgcg
     2221 ccgtacgcgc ggcacccggc ccccggtgtt cgtccgttcc gatgaacgtc ccggccggtc
     2281 ggcgctccgg ccggccgccg ggctgggacg ctgccggcat ggaccggttc gagcagtgcg
     2341 cggttccggc cgtcccgggc ggcccggcgg ccgatgtcgg cacggtgatc gcgcggatgc
     2401 gcgcctatcg ctccaggtgg cctccccagg acggcgtcgc cgtcttcaac caggtctatc
     2461 tgacggtgac cgaggccgtc ggcgggcgga tcgccgacgg ttccttcgcg gacccgcaag
     2521 ccgtctccgt tctggacgtc cgcttcgcgg agctctatct gacggccgtg gagaccgagg
     2581 cctccggcgg gcgggcaccc gactgctggc gggcgctctt cgcctaccgg cgccatccgg
     2641 gtgtgcgccc gcttcagttc gcccttgccg ggatcaacgc gcacatcggt cacgacctcg
     2701 ccctggccgt ggtggacacc tgccgtgcgc tcgactgcgc cccggaggac ctggagggcg
     2761 agttccgccg ggtgggggac ctcctggtga cgctggagga ggagatccgc gaggacctga
     2821 tgccggggcc cgacctgctg gagatcgccg atccgctgac ccatctggcg agcacctgga
     2881 gtctggagcg cgcccgggag gcgtcctggg cggcggcccg ggtgctgtgg cggctgcgcg
     2941 gggtaccgcc gctcgccgag gagttccgga cgcgcatgga cgcgggggtg ggcctggtgg
     3001 ggcgcctgtt gctcaccccg tgccgctgag acgtctcgcc acccgcccct ctcccgcgcg
     3061 ccccctgcct cagtcctcgg gcagttcgac cggggcgatc tcgtcgaaga cgtcgccggg
     3121 gccggggttc gacgggtccg tgccgccgcc gaactggtgc atcacgcccc acacggcgtt
     3181 gagcgcggtc tgcacggcgc cctccgccca gcccgcggtc cacgagatgt cgtcgccggc
     3241 caggaacagg ccgcgcttgt cggcgggcag ccggtcctgc atgaagtggg tgaacaggcg
     3301 ccgctgatag cggtagtggc ccggcaggtt ggccttgaac gcgcccatga agtacggctc
     3361 gttctcccag gacacggtga ccgggttgcc gatgacgtgc gagcggatgt cgacgcccgg
     3421 gtagatctcc ccgagcgact tgagcatgac ctccatgcgc tcgttcggtg agagcgggag
     3481 ccacttcagg ctgtcgtcgc accaggtgta cgagaggcag atgacggcgg gccggtcggg
     3541 gccgtcgtcc agcaggtagg tgccccgggt catccggtcg gtgagggtca tggacatggt
     3601 gtcgcggccg gtcgtctcgt ccttgtccag ccagaacggc cggtcgacgg ggacgaacag
     3661 cttggacgac tccatgtagt gggtgcgctc catcgccgtc cagtggtcga tcgggaagag
     3721 cgcgtcgtcg caggcgatct tggagaggag cagccatgac tgccccgtga agaccacggc
     3781 acggtagctg cggatgtcgc cggcggcgtc ggtgacggtg atccggttcc ccgccgtgcg
     3841 gtcgagccgg gtcacggcgg gccggggctc cccgccgtgc agggaggaca gcgacgtgcc
     3901 gagcggccag tgcgtgatct tctgcggctc gcggtcccag agccgcagcg gaagctgctg
     3961 gctgccgccg acgatcccgc ggtggtggtc gtcggcctcg gtgtagacga cccgcaggat
     4021 ctccaggatg gagttgggga agtcggtgtc ccagccgccg gtgccgaagc cgacctggcc
     4081 gaagatctca cggtgccgga aggaggtgaa ggcgtccgag gcgcagagga agccgtagaa
     4141 ggtctggttg tcgagcttct cgaccagctt cgaccagatc tcccggatgc gcggtacgtc
     4201 gcgctcgcgc atcgcccggt tcatgtcgga gaagtcggcc ccctcctcca ggcaggtgtt
     4261 ccaggccgcg gccacgtcgc ggtagacctg gggcaggtcg tcgatggtcc gcgcgtagtg
     4321 cgactcgccc ttgaggtcca cgacggtgga cggggtggcc ggtgcgagcg ggttggggaa
     4381 cggcctggtc tccaggtcca cgaggtcgat gtagtgctgg agcgccgtcg aggagggcgg
     4441 gaagcgcatc gcacccatct cggcggtcag cgaggggtcg cagccctcga agccgacggt
     4501 ccgcagccgg ccaccgatcc ggtccgcctc gtagacgacc ggcttcaggc ccatcttcat
     4561 cagctcgtag gcggtgatga tgccggagag cccgccgccg acgacggcga cctcggcccc
     4621 gtgctcggtg gcgggtacct ggccgatgcc cgcggggtgg gcaaggaagt cgtcgtacgc
     4681 gtacgggaag tccggcccga acatggtgat cggcggctgg gcgtcggtgt gctggacggc
     4741 gttgggcacc gtggacgtca tggggtacgg actccttggc ggatggcagc gtgaggtcgg
     4801 ggggagaggc cgttctccca tggtcgcccg gagcgggtgc tcaggcgagc gcgccgtaca
     4861 acgcgggcct gcggtcccgg aggtacgggt tggccgtgcg cgaggcgtcg agcaggccgg
     4921 ggtccacgtc gccgacgagg agttcctcgc cgcgaccggc ccggacccgc gcggtgccgt
     4981 cggggccggc caggcagctg agcccgatga actcgaactc gccttccggg ccggtcctgt
     5041 tcacgtaggc gatgtacatc tggttctcga acgcgcggac cggcacgacc gattcggcga
     5101 cgaacggata ggggtgcatc agcgcggtcg gcaccagcag cagcccggtc ccggcgagcg
     5161 cgtgcgcccg gacgttctcc gggaactcga cgtcgtagca gatcagcagc ccgatccgga
     5221 cgccgtccag ctcggcctgg accaccgggc ggtcgccggg ggtgaaccag cgctgttcga
     5281 aggggccgaa gagatgggtc ttgcggtagt cggcgagcgc cgtcccgtcc gggccgacca
     5341 gccgtgtcgc gttgaagacc agctcgccgg agcgctccgg gtagccgtag aggacggcga
     5401 tgccgtgccg tgcgcagagc tcggagacgg cctgcgccga gggtccgtcg gcgggttcgg
     5461 ccaggctggg gaggtcgtcg ccgagggcgt atccggtgag gaacagctcg gagcagacca
     5521 gcagccgggc gccggcggcg gcggcccgcc cggccgcctc gtcgatcagg ccgagattgt
     5581 gttccacgaa gccggggcgt ccggagctct ggagcagggc ggtacgcaac gacggcatgg
     5641 ctgacctcgg acggtacggg cggggcgggg agacgtatcg acggtacggg gcggcgctcg
     5701 ggcccgacaa ggcgtggatg ttgcgcatcc accgtcgatt cgttgcgcga gaaggcgctg
     5761 tggcggcgat tcgttgcacg gcgcgtcgtc gcaggtcaga agggtgatct gggtcggtgt
     5821 ccgcctacgg cttcgcccac ctccgcgacc gccgccacca cccggacgta ctcgaccgcc
     5881 ctcgacccgt acccgggccg cttcgtcgtc cacggcccgc cggccgccgt cctggaggga
     5941 ggccggcccg gcggcatggt gctgatcgag ggcgtcggcc ccggctacgg ccccgccggg
     6001 cgtgcggaga agctacgggc cgagaccgag ggcagtgcgg ccccgccgcg gacggatctt
     6061 cctcaggcgg gcggtccctg ggagtagcgg cgcagcagcg gcgacagcac caggacggac
     6121 ttggtgcgct cgatgtaggg ctcgcccgcg atgcgttcga gtacctgctc gaagtggcgc
     6181 atgtcggcgg cgaagacctg gacgaccgcg tcggcctccc cggtcacggt ggaggcggag
     6241 gcgacctccg ggaagcgggc cagtccctgc ttgatcgcct cgggggcggt gttgcggctg
     6301 cagtagatct cgatgaagcc ctcggtctgc cagccgagcg cggccgggtc cacccggacg
     6361 gtgaagccgg tgatggctcc ttcggcgcgc agccggtcca cccggcgctt cacggcgggg
     6421 gcggacaggc cgacgagcgc tccgatgtcg gcgtaggagc gccgggcgtc ttcggcgagg
     6481 gcgtggacga tgcgttcatc gaggtcgttc aggcgcacgt cgggcggatc acttctctgc
     6541 ggtcggattc gggggcggcg cgggccgccc ccgaagtaga ccacgggacc cggtgacctg
     6601 cccgagcccg ccgggtcaga aggggaaccg cgaacggccg tactgcaccg agatccactt
     6661 ctgggtggtg aaggcctcca gggtggcgtc gccgttgaga cggccgaggc ccgagttctt
     6721 ctcgccgccg aacggtacga cgggctcgtc gtggaccgtg ccgtcgttga tgtggatcat
     6781 gccggtgtgg atgcggcggc ccacccgtac gccgcgctcg atgttgccgg tgtgtacggc
     6841 gccgctgagt ccgtagggcg tgtcgttggc gatccggacc gcctcgtcct cgccgtcgaa
     6901 gggcaccagc agggccacgg ggccgaagat ctcctcgtgc aggaccgggg atccggcggg
     6961 aatgccggtg agcaccgagg ggctcaccag gttgccgtcg gcgcggccgt gcagcagcgc
     7021 cgtggcaccc tcctccaccg tgcggtcgac gatcttggac accgcgtcgg cctgcgagga
     7081 gttgatcagg gggccgatgt gggtcgccgg gtcggcgggg tcgccgacgc gcagggaagc
     7141 gaccttggcg acgaacttct cggtgaactc ctcctcgacc gcgcggtcga cgaggatccg
     7201 gttggcagcc atgcagacct ggccctggtg cacgtaccgg ctgaagacgg cggcgtcgac
     7261 ggcgtagtcg atgtcggcgt cgtcgaggac gatcagggcg ctgttgccgc cgagttcgag
     7321 tacggcccgc ttgaggtggg cggcgcacac cgtggcgacg tggcgcccga ccttgtccga
     7381 gccggtgaag gagatgagct gcgggacggg gtgctccagc agcgcgtcgc cgatctcggc
     7441 gatgtcggtg accacgacgt tcagcagccc cgccgggagg ccggcctcct cgaacacctt
     7501 ggccagcagc gtgccgccgc agaccggggt gttctggtgc ggcttgagga cgacggcgtt
     7561 gccgagcgcc agggcgggcg ccacggactt gagcgagagc aggaagggga agttgaaggg
     7621 gctgatgacc ccgacgacgc ccacggggac gcggtggacg cggttctcct tgccctccac
     7681 cggcgacggc aggatctccc cggtgggccg cagcgcgagc tggactgcct cgcgcaggaa
     7741 ctccttggcc aggtgcagtt cgaacgcggc cttcagacgg gtgccgccca gctcggcgac
     7801 gatcgcctcg gcgatctccg cctcccgctc ctccacgacc cgcagcgcct tctccatcac
     7861 ggcccggcgc tcgtacgcgt tggtgtcggc ccagccccgc tgggcccgct cggccgcccg
     7921 gtacgcctgg tccacctcac cggccgtggc cacggtgatc gacgcgagct tctccccgtc
     7981 gtacgggttg aagtcgatga tgtcccagga ccccttcccc ggcctccact cgccgtcgac
     8041 gtactgaagg gccaggtcgg tgaagaagga ggacatgagt tcccttaccg cagagggggg
     8101 gcagctgatt gccgctcata ttacttataa atcagctgag ttgaaggacc gtccggccct
     8161 ggcggttcgg ccggaactca tgcgcgtggc ccctcccgga acactccggg aggggccacg
     8221 tgcgaggcgg tgcggggatc agttccagct ggcgtgcagc ggcttgccct ccgcgtaacc
     8281 ggccgcgctc tgcacgccca cgaccgcctt ctcggcgaac tcctccagcg agccggcacc
     8341 ggcgtaggtg cacgacgagc ggaccccggc gatgatcgag tcgatcaggt cctccacacc
     8401 cgggcgtgcc gggtcgagga acatccggga ggtggagatg ccctcctcga agagcccctt
     8461 gcgggcacgg tcgtaggcgg actcctcaga ggtgcggttc ctgaccgcac gggccgaggc
     8521 catcccgaag gactccttgt agtaccggcc gtccgcggac tgctggaggt cgcccggcga
     8581 ctcgtacgta ccggcgaacc aggaaccgat catcacgttg gacgcaccgg cggccagggc
     8641 catggcgacg tcacgcgggt gccggacacc gccgtcggcc cagacgtgct tgccgtgcct
     8701 gcgcgcctcg gcggcgcact ccaggacggc cgagaactga ggccgaccca caccggtcat
     8761 catccgggtg gtgcacatgg cgcccgggcc cacgccgacc ttgacgatgt cggcaccggc
     8821 ctcgacgagg tcgcgcacac cctcggccgc gacgacgttg cccgcgacca gcggcacccc
     8881 ggggtcgagc gcccgcaccg cggcgaccgc gccgagcatg gactcctggt ggccgtgggc
     8941 ggtgtccacg acgagggtgt ccacccccgc gtcgaggagc tgccgggcct tgccggcgac
     9001 gtccccgttg ataccgacgg cggcggcgat ccgcagccgt ccggcgtcgt ccgtcgccgg
     9061 ggtgtagagc gtcgcccgca gcgccgcctt gcgggtgagg atgccgacga gccggccgtc
     9121 cgcgtcgacg gcgggggcga gcttgcggtt ggccccgtcc agcgtgttga aggcgtcccg
     9181 gggctcgatg ccggcgtcga gcaccaccag gtccttggac atgacctcgg acagctgggt
     9241 gaagcggtcc acaccgctca ggtcgtggtc ggtcacgacg ccgaccggcc ggttctccga
     9301 gtcgacgacg atgcccgccc cgtgcgcccg cttgtgcagc aacgacaggg cgtcggcgac
     9361 ggtctgcccc ggggccagca cgatcggggt gtcgagcacg aggtgacgct tcttgaccca
     9421 gccgatcacc tcggtgacga cctcgagcgg gatgtcctgc gggatgacga ccaggccgcc
     9481 gcggcgggcc accgtctcgg ccatccggcg gccggcgatc gcggtcatgt tcgcgacgac
     9541 gagcgggatg gtggtgccgg tgccgtccgg cgaggagagg tccaccgcct gccgggaccc
     9601 tacggcggaa cggccgggga ccatgaagac gtcgtcgtac gtgaggtcgt aggggaccga
     9661 gggggaggcc gtgtgacgac cggtgccggg ctcaagaaaa cgcataacac tcattttttc
     9721 atacgaaacg gtgcaggtcg tttctccgaa gacacagcaa tgaacccccg cgttcgtatg
     9781 ttcctccgaa gaggcgaccg ggggggccgg gacaagcgga acctgcctta cccggggacc
     9841 ttacccgaac aggattcaac caatcgtgat cacgatccct ggaccaggtg acgaggggtc
     9901 aggtagcttc accaccgcag gatccgtggt aaccggcgca ccgctcacgg atgcccggaa
     9961 caccgtcacg cgttcgaccg gagaggatcc agatccacct gtggagagcg aactgcctga
    10021 catctactgc ccgttcccgc agcggagcaa cccgcacgtc gcggccaccc gcgcgcacct
    10081 cgacacctgg acgcgctcca ccggcctggt ccaccgggac tcggcgagac agcgcttcga
    10141 gcaggccgac ttcggtgcgt tcgtcggcat ggtccatccg acggccggca gcgagcacct
    10201 ggacctggtc gccgactggt tcgtctggct cttcctcgtc gacgaccagc tggacgacgg
    10261 ccatctgggc cgcagccccg agcgcgtacg cgacgtggtg gcccggatgc gggccgtggt
    10321 cgagggcgtc gctccgcacc cgctgcccgg cgaggagccg cccgcggccg tcgtcgccct
    10381 ctgcgacctg tgggaacgta cggtcccgcg ggcggccccg cactggcgca cccgtttcac
    10441 ctggcacctc atgacgtacc tgacgaccgc caccacctgg gaggccggca accgggccgg
    10501 cggtgtggtg ccgagcgagg cgacgtacat cgccaagcgc cgccacacgg gcgcgatcca
    10561 cgtgtgcatg gacctgatcg agatcgtggc gggcatagag gcgcccgagt ccctccacaa
    10621 cgatccccgg ttcatcacgg cgctggaggc atcgtgcaac gtcgtctgct gggccaacga
    10681 cgtctactcc tacgagaagg agcaggtgct cggcgagatc cacaacctcg tccacctggt
    10741 gcgccaccac cgcggttacg gtgagcagcg ggcgctcgac catgtctgcg ccgagatagc
    10801 cgcggagacc gagcggttcc tgaccgccga ggacgagctg atcgacatgt acccgcagct
    10861 cacggacctg ctcgtgccct atctcgacgg gatgcggagc tggatgcgcg gcaacctcga
    10921 ctggtcgcgg cagacccccc gctacaaccc ggcggccgtc agccagtaca cggcgcccgg
    10981 ggagtacctg gaggagacgg tgctcggcgt ggccacggac tcggcgggcc actgagcggc
    11041 cgggcggcga acggcacggc gaaggccagt caccccctgg ggtgaccggc cttcgccgtg
    11101 cccgcgcgga gccgcgggca cgggtcagtc gtcggggtcg gcccgctcca gtgccgggcg
    11161 ctgccccgcg gcggactccg tcagcaggta gtcggcggcg gccgtgtccg tgacgaggct
    11221 ggtgaccagg ccggagcgca ggaccgcccc gatcgccgcg gccttgcgct gccccccggc
    11281 gatggcgacg acctcgggga tccggcgcag ccggtccgcc tccacggtga tgcaccgctc
    11341 gccgaggtcg cggccgaccc ggcggccgtc ggagtcgaag aggtgggcgg acatctccgc
    11401 cgccaccccg agcgaggcgt agtgcgcccg ctcctcgtcc gagagcatgt cgtggacggt
    11461 ggagatgccg ggctcccagg aaccgatcga gaccgcggcg accgtcacct tgtcgaagta
    11521 ctcgaaggcg cgggcgatcc ccgtctggtg gcgcagcgcc gcggcggtcg ccgggtcggg
    11581 cagcagcatg ggcgcgtaga tggggtgggc ctcgccgccg gacacctgtg ccgcgcggcg
    11641 gaccgcctcg acggagccgc gctcggcggt cccggcgtcg tagaccccgg tgagctggac
    11701 cacggtgcac gggggcaggc ggtcgagcgc cgccgccatg tggatggtgg accggcccca
    11761 ggccaggccc agcacatcgc cctcgttcac cagctcgccg agcaggtcgg cggcgacctc
    11821 gcccaggttc tccggatcgg cggcgtcgtc ctgctcctcc gccggggact ccaccacgac
    11881 cgcgtgccgc aggccgtacc gtgcgcggag cgcgtcggag cgctccgcgt cgagctccgc
    11941 cggtacccgg atctcgatcc gtacgagatc acgctccagg gccgtctcca ggacccgggc
    12001 caccttgaag cggctgacgc cgaactcctc ggcgatctgg atcttcgact ttccctcgag
    12061 gtagaaccgg cgggccatgg ccgccgcctg caccagctcc gcgggtccca tccgcatggc
    12121 tgaccgaccc gccgagatgc cagacaccgc gatctccttc aactctctac gcgctcgata
    12181 cgccgtcatc ctgtcagatc cggcgatcct tgatcaggcc cgtggggccg cgttcatctg
    12241 ccctttgttc aatggccgca ggcccaggtg gccccggccg tggccgcgtc cgcccgggcg
    12301 cgcagcgccc ggaccgcgtc ggccgggtcc tgcgccccgt acaccgccga gcccgccacg
    12361 aagacgtccg caccggcctc cgcgcaccgc tcgatggtgg acgccgagac cccgccgtcg
    12421 acctggagcc acagttcgag cccgtgcttg gagatcagct cacgggtgcg gcggatcttc
    12481 ggcagcatga tgtcgaggaa cgcctggccc ccgaaccccg gctccaccgt catgatcagc
    12541 agcatgtcga gctcggggag caggtcctcg tagggctcga cgggcgtcgc gggcttgagc
    12601 gccatcgagg cgcgcgcccc cttcgcccgg atctcccgcg ccagccgtac gggcgccgcc
    12661 gcggcctcga cgtggaaggt gacggagccc gcaccggcct cgacgtactg cggggcccag
    12721 cggtccgcgt cctcgatcat cagatggcag tccagcgggg tgtccgtcgc cttgctcagc
    12781 gcctccacca ccggcacgcc gagggtcagg ttggggacga agtggttgtc catgacatcg
    12841 acgtgcagcc agtcggctcc ctcgacggcc ttcgcctcct cggcgagacg tgcgaagtcg
    12901 gcggacagga tgctggggtt gatctgcgcc atggaccaag cctgccatgc tccggcccac
    12961 ttccccgcct cggtgcgccc caaagcctca cgggatcatt acggttcgca caattccggc
    13021 ttttcaccct gcccgcagcg aggtgtgcgg cgctcaggcc gtccggcgca gcagggccag
    13081 gtacatcgcg tcggtgccgt gcaggtgcgg ccacagctgg atgtcggggc cgtcgcccag
    13141 cgccggtacg cccggcagca gcgggcgggc gtccacccac tccgcctccg cgctcgcacc
    13201 gccgcgtccc ttgagcacgt cctcgacgac cacccgggtc tccgcgaggt gcggggagca
    13261 ggtcgcgtag ccgaccacgc cgccgacccg gacggccttc aacgcctcgc gcagcagacc
    13321 gcgttgcagg ggggcgaagc tctccaggtc ctgcggccgg cgacgccagc gggcttccgg
    13381 ccggcggcgc agcgcgccga ggcccgagca cgggacgtcc atcaggaccc ggtcgaagga
    13441 gcccggccgc cacggcggcc gggtgccgtc ggcggtgatc acctggtgcg ggcccgggtt
    13501 gccggccagc gcgcgctcga cgaggcgggc gcggtgcggc tgcttctcgg cggccagcag
    13561 ggtggcgccg cgtgcggcgg cgagcgcgcc cagcagggcg gccttgcccc cggggcccgc
    13621 gcagccgtcg agccagcggc tgtcgcggcc ctcgacgggc gcctgggcga gggcggccgc
    13681 gacgagctgg ctgccctcgt cctgcacccc ggcccggccc tcctggacgg cggtcagggc
    13741 gccgggctcg ccgccctcgg ccatgcgtac ggcgtagggg gaccagcggc ccgccagccc
    13801 gctctcctca ccgagggccg ccagcagttc gtcggtggtg gagcggcccg gacgggcgac
    13861 cagcgtcacc tcggggcgtt cgttgtcggc ctccagcagg tcctcgatcc cggcccggcc
    13921 gccccccagc gcgtcccaga gggcggagac cacccagcgg gggtgggagt ggacgacgga
    13981 gaggtgctcc tcggcgtcct cgtcgtaggc cggggcgacc cgctccagcc agccgtcgag
    14041 gtcatgggcc gagaccttgc ggagcaccgc gttgacgaac ttcgcgcgcc cctcccccag
    14101 cacgacccgg gcgagctcga cgctggcgga cacggccgcg tgcgtcggga tgcgggtgcc
    14161 gagcagttgg tgcacgccca tctcgatgac gtccagcacc ggggggtcga cctcgcgcag
    14221 cggccggtcg acgcaggcgg cgacgatcgc gtcgtaggtg ccctggcggc gcagggtgcc
    14281 gtagaccagc tcggtggcca gcgccgcgtc gcggccgtcg aagtcgccct tggcgcgcgc
    14341 cttcttcagc agcggcggca ggacgaggtt ggcgtacgcg tcgcgttcgt cgacggccct
    14401 gagcgcttcg aaggcgagga accggacggg gtccttctcg gggcggcggt gctgcttggc
    14461 cggacggcga cgctgctggt cgttcacgtg aaaggtgctc cgcttgaggg tgaggggacg
    14521 atcgcctcca gcgtacgtcg ggccgccgcc gggtccgcgc ccgcgcccgc tcaggccccc
    14581 agcagctccc cgtgggcgat gcgcacaccg cgggcccagt cggcggcgcg catcggcttc
    14641 ttgccctgcg gctggaccca gaggagctcg acggcgtacg agccggtgcc cacgtacacg
    14701 ttgttcttgc ccgcggacag ttcgccgggg gccaggtcgg tgcggtcggg gacggggacg
    14761 gcctggacca gcttgaggcg ctcgccgcgg aagagcgtcc aggcccccgg tgcgggggtg
    14821 cagccgcgta cgacgcggtc gacccgcagc gccggctccg cccaccgcac ctgggcgtcc
    14881 tcgacggtga tcttgggggc gagggtgatg ccctcggcgg gctgcgggac ggcgtgcagg
    14941 gtgccgtcct cgatgccgtc catggtcgcc gcgagcagtc cggcgcccgc gaaggccagc
    15001 cgggtgagca ggtcgccgct ggtgtcggtg ggccggacct cctcggtgag gacgccgtag
    15061 acgggcccgg agtccagccc ctcctcgatc aggaaggtcg acgccccggt cacctcgtcg
    15121 ccggccatca ccgagtgctg gacgggggcg gcgccgcgcc aggcgggcag cagggagaag
    15181 tgcaggttga cccagccgcg ggcgggcacc tccagggcgg acttgggcag cagcgcgccg
    15241 taggcgacga ccgggcagca gtccggggcg atctcccgca gccgggccag gaagtcctcg
    15301 tcgcgcggcc tggccggctt gaggatctcg ataccggcct cctcggcccg ctcggccacg
    15361 gggctggcga ccagccggcg gccgcgcccg gcgggagcgt cggggcgggt gacgacggcc
    15421 gccacctcgt ggcgctcgga ggcgatcagg gcgtccaggg cggggacggc gacctcgggg
    15481 gtgcctgcga agaccagctt catgggtggc gcactgcctc tcggggcggg acgtacgggc
    15541 gagcagcgca ccagtctaag cgctgccccg tacggcggcg gggggcgtac gcacgcccgt
    15601 gcgccccgcg catatgcgca tacgcccctg ttgcgtgacc ccgaggccag gtgcggcgtt
    15661 ggtcaagtga gattgaccga agcggaccgt cgtacgcggt ccgatccctt caacgccggt
    15721 tcgagaggct tgttcatggc cgaccacgca acccacgacg cccaagcgcg tgcaagtctg
    15781 cacctgttgg tgcgggacat cgagcgggtc cggcggcagg tggacgcgtt gcgcacgctg
    15841 accgcgcagc tgggcaacgt ctaccgtccg cgccgctccg gcccgtccgc gggcttcgtc
    15901 gtctacggga gggcccccgc cccgacggtc cggctcgcgc aggaactgcg ggacagcgtg
    15961 gagacgctgg tgacggccgc ggtggacttc gaccgctcgc tgggcttctc gtgggacgcg
    16021 gtgggctccg ccctcggcgt caccaagcag gcggtgcacc gccgttacgg ttcgcgccgc
    16081 acgaccgcgc agtcggcggc gggtgaggcg gcggagacgg cggcccgcaa acagcccgcc
    16141 ccggcgggca cttcggccgc actgcccgtc gtgccggcgg cccgctccat gccgccgcag
    16201 ccctctcccg gaccggcttc cccgacggac cgtgcggcac ctcgcgagga actgcggccc
    16261 ggtgccttcc cgggcccgcg caacggctga cggtaccggg ctgcccgcac cggggcagcc
    16321 caccgtggtg cgcccggtcc tcgcccccct cagccgatgt ccggcggatc gatcctgatc
    16381 cgcaccgggt cgccgctccc ccgggccgta cgcgccgccg acgcagcctt caacgcgtgc
    16441 gcgagcgccg ctccgcgccc cggcggcacc ctgatcagtg cccgctccca gacctcgccc
    16501 ggcggggcgt cccccggcct gcggggccgc ccggccgccg tcgcgggcac cggtacgggc
    16561 ccgaggacct cggcctgtgc cggcagctcc gccgtggcca ggaacgcggc gagcgcttcg
    16621 ggcgggcccg tcaccgacgc catccgtgac accggcggga agccgagctc ggcccgttcg
    16681 gcgagctcac ggcgggcgtg gcccaccggg tcccagcgca ccagcgcctg cacgggccgc
    16741 agggtcggct cggcgacgac caccaccgtg cctccctcgg accggccgcg caccagggcg
    16801 gccgccgccg tccagcgccg cagcgcctcc tcccccgccc gcaggtcggg gcggcccacc
    16861 atcgcccagc cgtccagcag cagcgcagcc gcgtagcccc cttcggccac cggctcggcc
    16921 ccgggtgtgc tgacgaccag cgcgggctgg tccggtacgg aatcgagcac atggtcgcgg
    16981 cccgacgtcc gcacgggaac ggccgggaac gcccgcccca gctcctccgc ggtcctgcgg
    17041 gcgccgacga tctgcgcccg cagccgcacg ccaccgcagg ctccgcaccg ccaggccgtc
    17101 tcggccctcc cgcaccacgc gcagtcgagg tcctgccggt cggtggcctg caaggggccc
    17161 gcgcagtgcc ggcaccgcgc gggttcgcgg cagcgctcgc aggccagccg gggcgcgtaa
    17221 ccgcggcgcg gcacctggac gagcaccggg ccgccgcgca gcccgtcccg gacggtctgc
    17281 caggccaggc tgggcagccg cgccgaacgc gccgccccgt cgcgcgccag ctcgccgtcg
    17341 tcgaccgtac gcacgagggg tgctgctgac cgcagccgct cccgttccgc acgcagcggc
    17401 agcgcccagc cgctctcgac caactgggcg gcctccaccg tgcagttgat cccgcccagc
    17461 aggaatccgc accggccgtg cgccgcccgc agctccagta cctcccggac gtgcgggaag
    17521 ggggcgttgt cgtcgctgtg gctggagtcg ccgtcgtccc agacggccac cagtcccgga
    17581 tcggccacgg gggcgaacat cgcggcccgg gtcccgacca ccgcgcgcac ggacccgcgc
    17641 cggaccgcga gccactgccc gtaccgcttc tcgggcccgg agtcggcggt gagcagcgcg
    17701 tggtgcccct tgcccagcag cgcggtgagc gccgcgtcca cccgccccgc cgcccggccg
    17761 tccggtacga cgacgagcgc gcccctgccc gacgccaggg tcgcggcgac ggcccgggcg
    17821 atctcctcgg gccagtgcgg gccgggcagc gcggtccaca cggcccgggg cgccccgccc
    17881 tcggccagcg cccgcaggaa gccgggtccc tgggtgtacc gctcccaggt cccgggcgag
    17941 gggacgggcg gcggcggcag gggcgcgggc gaggccttgg actcggccct gccgttcctc
    18001 gggggcacgg cgagctggag cacgtcggcg aggctgcccg cgtagcggtc ggcgacggca
    18061 cggcagaggg cgagcagctc gggcccgagc accggctcgg gcgagacgac gtaggccagg
    18121 gccgcgaggg cgccctggta gtcggaggag gcgcgccgct cgacgaggaa cccgtcgatg
    18181 agcccgccgc cctcgcgccg tccgccgcgc acctgccgcc cgccggcgcc gaaccgcacc
    18241 cggacgcgga cgccgggctg tgcgtcggcg tcgagctcct cggggacggc gtagtcgaag
    18301 tactggtcga ggtggagcgc gcccttgttg accaggacgc gggcgacggg cagctcctcg
    18361 gcgagcgcgg cgccccgcca ggtccggggc ttcgcgcggg gcaccttggc ccggcgtacg
    18421 gtctcccgga tcagcgcaag ctgctccggt gccccggcgt cgggctcctc ggaccgctcg
    18481 ttgtcgctgc tcacagccac cttcctacca gaccccactg acagcggcgg ggcccggccg
    18541 ggcccgcggc gccccgcacg caccggggcc cgggcaccgt cgtgcggtgt ccgggccccg
    18601 gcgtacgtga cggcggcggc gggacctcag agccctgcgg ccgtgcgcag cgcgtccacc
    18661 cggtcggtgc gctcccaggt gaagtcgggg agctcccggc cgaagtggcc gtaggccgcg
    18721 gtctgggcgt agatcgggcg cagcaggtcg aggtcgcgga tgatcgcggc cgggcgcagg
    18781 tcgaagacct cgccgatcgc gtgctcgatc ttctccgtgt cgaccgcggc ggtgccgaag
    18841 gtctcgacga acaggcccac cggctcggcc ttgccgatcg cgtaggcgac ctggacctcg
    18901 cagcgggcgg cgagcccggc ggcgacgacg ttcttggcga cccagcgcat ggcgtaggcg
    18961 gccgagcggt cgaccttgga cgggtccttg ccggagaagg caccgccgcc gtggcgggcc
    19021 atgcccccgt aggtgtcgat gatgatcttg cggccggtca ggccggcgtc gcccatcggg
    19081 ccgccgatct cgaagcggcc cgtcgggttc accaggaggc ggtagccctc ggtgtcgagc
    19141 ttgatgccgt cctcgacgag ctggttcagg acgtgctcga cgacgaactc gcggatgtcg
    19201 ggcgcgagga gcgagtccag gtcgatgtcg gacgcgtgct gcgaggagac cacgaccgtg
    19261 tccaggcgga gcgccttgtc gccgtcgtac tcgatggtga cctgggtctt gccgtcgggc
    19321 cgcaggtagg ggatggtgcc gttcttgcgg acctcggaga ggcggcgcga gagccggtgc
    19381 gccaggtgga tcggcagcgg catcagctcg ggcgtctcgt cgcaggcgta gccgaacatc
    19441 agcccctggt cgcccgcgcc ctgcttgtcg agctcgtcct cgtcgccctc gacgcgcttc
    19501 tcgtaggcgg tgtcgacgcc ctgcgcgatg tccggggact gcgccccgat ggacaccgag
    19561 acaccacagg aagctccgtc gaagcccttc ttggaggagt cgtagccgat ctcgagcacc
    19621 ttgctgcgca cgaggttggg gatgtcggcg taggccttgg tcgtgacctc acccgcgaca
    19681 tgcaccagac cggtggtgat cagggtctcg acggcgacgc gcgaggaggg gtcctcgcgc
    19741 aggagcgcgt cgagaatcgt gtcgctgatc tggtcagcga tcttgtcggg gtggccctcg
    19801 gtgacggatt ccgaggtgaa gagacggcgg gacacatcgc tccctggggt tgcagcggct
    19861 gctggctgat catgggtgga cggccgggag ctgcgcccgg cacgtccgtc gaccagttta
    19921 tcggtcgctt ccggcggatg ggtcacgtgt ctcgcccctt gggagccctg tgacctgcgg
    19981 cactgttgac tgcggtacga caatcactcc ttccgggcgc ggtgacacgt gctggttcag
    20041 gcttctgccc gccggagcgg cgcataggca atctagccca accgggccgt cacgaggtcc
    20101 cagaccacgt cggcgagtgc ttccttcggc ccgtacggca ccggcgtctc ggagccgtcg
    20161 gcgccgagca cgaccgcctc gttctcctcg gagccgaacg tcttgcgctc accgacctcg
    20221 ttgacgacca gcaggtcgca gcccttgcgg cgcagcttgg cccggccgtt ggcgaggacg
    20281 tcgtcggtct cggcggcgaa tccgacgacg agctgtcccg ggcgggcccg ctcgccggcc
    20341 acctcggcga ggatgtcggg gttgcggacc agcgcgacgg gggcgggctc ctggccgtcc
    20401 ttcttcttga tcttgccggt ggcgtacgcg gcgggccgga agtcggcgac cgccgccgcc
    20461 atcaccacga cgtccgcgtc ggccgccgcc ttcagcacgg cctcgcgcag ctggacggcc
    20521 gtcccggcac gcaggacgtc ggcgccggcc gggtcgggca gcccggtgtt cgcctcgacc
    20581 agggtcaccc gggccccccg ggcgacggcg gtgcgcgcca gggcgtagcc ctgcttgccc
    20641 gaggagcggt tgccgaggta gcggaccggg tccaggggct cccgggtgcc gccggcgctg
    20701 acgacgacat gacggccggc caggtcacgc tcggcgggcc cgcggtccag gacacggcgg
    20761 cagacctcga agatctcccc ggggtcgggc agccgcccct tgccggtgtc cacgccggtg
    20821 agccggccga cggccggctc gatgacgacg gcgccgcgcc ggcgcagcgt cgcgacgttc
    20881 tcctgggtgg cggggtgctc ccacatctcc gtgtgcatgg ccggtgcgaa gacgaccgga
    20941 cagcgggcgg tgagcagggt gttggtgagc aggtcgtcgg cgaggccgtg ggcggccttg
    21001 gcgagcatgt cggcggtggc cggggcgacc accac
//
