LOCUS       NZ_GG667192            21095 bp    DNA     linear   CON 01-MAY-2024
DEFINITION  Corynebacterium lipophiloflavum DSM 44291 SCAFFOLD2, whole genome
            shotgun sequence.
ACCESSION   NZ_GG667192
VERSION     NZ_GG667192.1
KEYWORDS    WGS; RefSeq.
SOURCE      Corynebacterium lipophiloflavum DSM 44291
  ORGANISM  Corynebacterium lipophiloflavum DSM 44291
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Corynebacteriaceae; Corynebacterium.
REFERENCE   1  (bases 1 to 749727)
  AUTHORS   Qin,X., Bachman,B., Battles,P., Bell,A., Bess,C., Bickham,C.,
            Chaboub,L., Chen,D., Coyle,M., Deiros,D.R., Dinh,H., Forbes,L.,
            Fowler,G., Francisco,L., Fu,Q., Gubbala,S., Hale,W., Han,Y.,
            Hemphill,L., Highlander,S.K., Hirani,K., Hogues,M., Jackson,L.,
            Jakkamsetti,A., Javaid,M., Jiang,H., Korchina,V., Kovar,C., Lara,F.,
            Lee,S., Mata,R., Mathew,T., Moen,C., Morales,K., Munidasa,M.,
            Nazareth,L., Ngo,R., Nguyen,L., Okwuonu,G., Ongeri,F., Patil,S.,
            Petrosino,J., Pham,C., Pham,P., Pu,L.-L., Puazo,M., Raj,R., Reid,J.,
            Rouhana,J., Saada,N., Shang,Y., Simmons,D., Thornton,R., Warren,J.,
            Weissenberger,G., Zhang,J., Zhang,L., Zhou,C., Zhu,D., Muzny,D.,
            Worley,K. and Gibbs,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2009) Human Genome Sequencing Center, Baylor
            College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
REFERENCE   2  (bases 1 to 749727)
  AUTHORS   Qin,X., Bachman,B., Battles,P., Bell,A., Bess,C., Bickham,C.,
            Chaboub,L., Chen,D., Coyle,M., Deiros,D.R., Dinh,H., Forbes,L.,
            Fowler,G., Francisco,L., Fu,Q., Gubbala,S., Hale,W., Han,Y.,
            Hemphill,L., Highlander,S.K., Hirani,K., Hogues,M., Jackson,L.,
            Jakkamsetti,A., Javaid,M., Jiang,H., Korchina,V., Kovar,C., Lara,F.,
            Lee,S., Mata,R., Mathew,T., Moen,C., Morales,K., Munidasa,M.,
            Nazareth,L., Ngo,R., Nguyen,L., Okwuonu,G., Ongeri,F., Patil,S.,
            Petrosino,J., Pham,C., Pham,P., Pu,L.-L., Puazo,M., Raj,R., Reid,J.,
            Rouhana,J., Saada,N., Shang,Y., Simmons,D., Thornton,R., Warren,J.,
            Weissenberger,G., Zhang,J., Zhang,L., Zhou,C., Zhu,D., Muzny,D.,
            Worley,K. and Gibbs,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2009) Human Genome Sequencing Center, Baylor
            College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000159635.1-RS_2024_05_01
            Annotation Date                   :: 05/01/2024 01:00:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,353
            CDSs (total)                      :: 2,297
            Genes (coding)                    :: 2,213
            CDSs (with protein)               :: 2,213
            Genes (RNA)                       :: 56
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 21 of 84
            Pseudo Genes (incomplete)         :: 64 of 84
            Pseudo Genes (internal stop)      :: 11 of 84
            Pseudo Genes (multiple problems)  :: 11 of 84
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:27:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 281818
            Orig. end                         :: 302913
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG667192.1.
            This sequence is generated as a part of the Human Microbiome
            Project (HMP), funded by the National Institutes of Health (NIH),
            National Human Genome Research Institute (NHGRI) Large-Scale
            Sequencing Research Network and the National Institute of Allergy
            and Infectious Diseases (NIAID) Microbial Genome Sequencing Centers
            Program.  The mission of the HMP is to generate resources to enable
            the characterization of the human microbiota, the microbial
            communities living within human bodies, and analyze the role of
            these organisms in human health and disease.  See
            http://www.hmpdacc.org/ for more information.
            The sequenced strain was obtained from DSMZ.  The genomic DNA was
            prepared from a single bacterial isolate.  The sequence generated
            included at least 10 fold coverage of Roche/454 Lifesciences FLX
            fragment data and at least 8 fold clone coverage of Roche/454
            Lifesciences paired-end data.
            The Roche/454 Lifesciences sequence was assembled using the
            Roche/454 Lifescience Newbler assembler.  The contigs from the
            Newbler assembly were aligned with mapping tools such as Mosaic and
            Crossmatch and these data were used for error correction for this
            version of the draft assembly.  This draft assembly meets the HMP
            draft quality standards (more than 90% of the genome is included in
            contigs, more than 90% of a core set of bacterial genes are found
            with > 30% identity and > 30% length; more than 90% of the bases in
            the assembly have more than 5 fold sequence coverage, the contig
            N50 length is greater than 5kb, the scaffold N50 length is greater
            than 20kb, and there is less than 1 gap per 5kb).
            This is a reference genome for the Human Microbiome Project.
            This project is co-owned with the Human Microbiome Project DACC.
            Genome Coverage: 32x
            Sequencing Technology: 454; ABI
            Annotation was added to the contigs in April 2009.
            Product names were updated in June 2013.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21095
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11095](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11095)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(584..604)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    complement(704..721)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     misc_feature    718..731
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.77"
                     /tool="antismash"
     gene            750..1796
                     /locus_tag="HMPREF0298_RS04500"
                     /old_locus_tag="HMPREF0298_1203"
     CDS             750..1796
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018016735.1"
                     /locus_tag="HMPREF0298_RS04500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1203"
                     /product="C40 family peptidase"
                     /protein_id="WP_040422495.1"
                     /transl_table=11
                     /translation="MGKHSLPPRARRSAGTIAYTTVSLAVAGATVAGLVSPAHAEDLDT
                     LIAELGTVSDEATAKMEQIKDLEGQLEQARAELDDSARAAAAAQARAEEVRGARAMQQG
                     DVNAVATSTYRTLQVDNVVNTLGSATPQEVIDKTTYLGSISRKRQEQLDGLRAANEEAI
                     QAAREADVAKATAQYNRVKLDTQLAQLEKERADIEARIKDVEARVDALSPAAREAWTNQ
                     ANPVPADMLDPGAFGNAITAAALAQLGKPYGWGAAGPDAFDCSGLMVWAYSQNGKSIPR
                     TSQAQLAGGTPVSMSDLQPGDIVGYYPGVTHVGMYIGNGQVVHASDYGIPVQVVPLNSM
                     PVQGAVRY"
     gene            1798..2934
                     /locus_tag="HMPREF0298_RS04505"
                     /old_locus_tag="HMPREF0298_1204"
     CDS             1798..2934
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006063923.1"
                     /locus_tag="HMPREF0298_RS04505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1204"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_006839930.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.8e-37,
                     bitscore: 124.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLLVTNDFPPAVGGIQSYVRDFADEFVRRAGPDELLVFASTQD
                     ADAARRWDSNVGYTVVRWPRRVMLPTPATVREMRRLIREHGVDTVWFGAAAPLALMGAA
                     AKSAGARRVLASTHGHEVGWSMLPGARQVLSVIGRRADVVTYVSEYAVGRFRSAFGAMP
                     RFEALPSGVDKQFFRPASEPERAAVRSELGIRGPMIVCASRLVRRKGQDTLIDALPSII
                     DAYPDARLVIVGEGPYARALTRRARPLAESVVFTGAVDRARLRDIVAAADVFAMPARTR
                     GAGLDVEGLGIVYLEAQACAVPVVVGDSGGAPETVTDQTGVVVDGRDHDAVAAAIISLL
                     GDPARRREMGRAGRAHVERAFSWEALGDRLYNLLSPTG"
     gene            2946..3917
                     /locus_tag="HMPREF0298_RS04510"
                     /old_locus_tag="HMPREF0298_1205"
     CDS             2946..3917
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014800667.1"
                     /locus_tag="HMPREF0298_RS04510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1205"
                     /product="ROK family protein"
                     /protein_id="WP_006839931.1"
                     /transl_table=11
                     /translation="MLPETRRADAAPLTIGFDIGGTNTRAGVVTAAGEIIDSRSIETPH
                     DADELTASITRLVAEVRRDHDIAAVGAAIAGFLDPACEKVRFAPHLPWRNDAPVKAMLE
                     DAIGLPVRLEHDANSAAWGEYKFGAAKNAETWVFFAVGTGIGATLMHRGEIYRGAFGTA
                     PEFGHLTVVPGGRVCSCGKHGCLERYASGTALVDTAVEVASAGGYKACGLYRKVVDKRA
                     NGHDVMAAARSGDALGRAAVDTFADWLGQGLSIVADVLDPELIVLGGGVSDDADLFIDR
                     ARGAMTRDIVGAGYRPLPTLIRTELGPEAGMIGVADLARKLV"
     gene            3929..4666
                     /locus_tag="HMPREF0298_RS04515"
                     /old_locus_tag="HMPREF0298_1206"
     CDS             3929..4666
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005328940.1"
                     /locus_tag="HMPREF0298_RS04515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1206"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_006839932.1"
                     /transl_table=11
                     /translation="MVNKWYAVFKAILGPPLLVWNRPTIEGAHNIPRTGTAILASNHQA
                     VMDSFYLPLMVWRQLTFPAKKEYFTTPGVGGAIQRFFFSSVGQIPVDRSSSGAADDLER
                     AAEEVFADGKLMGFYPEGTRSPDGRLYKGRTGMARIAMKNNVDVIPVAMIGTRNANPIG
                     TFVPRPRRVRIKVGEPISPHAWARENGCDPDSREVARPFTDFIMEKLSELSGYEYVDAY
                     ASEVKKSLEAGHGYPAGTEPKTP"
     misc_feature    3938..3956
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            4682..4885
                     /locus_tag="HMPREF0298_RS04520"
                     /old_locus_tag="HMPREF0298_1207"
     CDS             4682..4885
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HMPREF0298_RS04520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HMPREF0298_1207"
                     /product="hypothetical protein"
                     /protein_id="WP_157464378.1"
                     /transl_table=11
                     /translation="MDRDLLIRVALCCVLVAAVMVATQTGRYINVVAPLAVIGVAVVMF
                     WPRRRGASAPDPAERDDASGRG"
     gene            4887..5420
                     /locus_tag="HMPREF0298_RS04525"
                     /old_locus_tag="HMPREF0298_1208"
     CDS             4887..5420
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018580626.1"
                     /locus_tag="HMPREF0298_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1208"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_040422497.1"
                     /transl_table=11
                     /translation="MRYFYDTEFIEDGATIELVSIGIVAEDGREYYAVSTDFDAAKANR
                     WVRDNVLDKLPSPGESEWKPNSAIRREVLEFVTAGPGHPELWAWVGAYDHVVLAQLWGD
                     MSALPKALPRYTRELKQYWEMAGRPKLPSLPKGNHNALVDARHNLAKFTACTAALPLGD
                     NGQVSIVREHHSTR"
     gene            5480..6868
                     /locus_tag="HMPREF0298_RS04530"
                     /old_locus_tag="HMPREF0298_1209"
     CDS             5480..6868
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018016741.1"
                     /locus_tag="HMPREF0298_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1209"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_006839935.1"
                     /transl_table=11
                     /translation="MSWTIDIPKDVLPDLPPLPGDLNERFQDVISRDAKQQPTWDANEA
                     GYVRKILESVPPVVLAPEIEVLKGQLADVALGKAFLLQGGDCAETFESNTEPHIRANVR
                     TLLQMAAVLTYGASVPVVKLGRIAGQYAKPRSSDLDENGLPNYRGDIVNGVEPTPEDRR
                     HDPARMVRAYANASAAMNLVRALTSSGTADLNHIHDWNRQFVASSPAGARYEALAREIS
                     RSLDFMRACGVNDEHLRTSEIYASHEALLVDYERAMLRLAEDSHGETKLYDLSAHQLWI
                     GERTRGMEDFHVNFAAMINNPIGIKLGPKATPEEAVAYAEKLDPNREPGRLTMVIRMGH
                     DNVRSVLPGIVKAVEASGHKVVWQSDPMHGNTFTASNGYKTRHFDKIIDEAQGFFEVHR
                     ELGTHPGGVHIELTGENVTECLGGAQDITDLDLPGRYESACDPRLNTEQALELAFLVAE
                     MLRY"
     gene            complement(<6914..8137)
                     /locus_tag="HMPREF0298_RS04535"
                     /old_locus_tag="HMPREF0298_1210"
                     /pseudo=""
     CDS             complement(<6914..8137)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003852190.1"
                     /locus_tag="HMPREF0298_RS04535"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1210"
                     /product="protein kinase"
                     /pseudo=""
                     /sec_met_domain="Pkinase (E-value: 2.3e-56, bitscore:
                     186.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELAVGDYLDNRYVIDRPIARGGMSTVYRCVDVRLGREVAAKVM
                     DNRYVDDHLFLTRFRREARAMAQLSHPNLVNVYDFSHEGDHVFLIMELIRGGTLRELLA
                     ERGPMPPHAAAAVMRATLTGLSIAHRKGMVHRDIKPDNILINLDHRVKLADFGLVRAAA
                     DATHSTDQIVGTVSYLSPEQVDGSPMGPASDVYSAGIVLFELLTGGVPFSGETPLAHAY
                     ARLNRDVPAPSSRIEGVPKLVDELVATATSRRPEDRFVDAAEFLAALDDVAAALGLPDY
                     VVPVPRDSAANRAAAHPTAVTLLNTPQPQPAPPAFERRLFPESGSTRVAGAAPQPPVTP
                     VPAAPPPAAPSPVPVAPPPVAPPPKPLTNRSALGTAIFVALSLLVIALVAIGAWWFGSG
                     MYGELPALI"
     gene            8208..8576
                     /locus_tag="HMPREF0298_RS04540"
                     /old_locus_tag="HMPREF0298_1211"
     CDS             8208..8576
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018297095.1"
                     /locus_tag="HMPREF0298_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1211"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_040422499.1"
                     /transl_table=11
                     /translation="MTTPNIDLDGLLANETLLPLPDVAEYLGVPVTKVHDLVGAHKLLV
                     YRKDGVKYVPERLLGEDGELSKFVGGAIMVLHDGGYSADEILHYLFTDDESLPGRPIDA
                     LHSHGAREVIRRAQAMAF"
     gene            complement(8548..10062)
                     /locus_tag="HMPREF0298_RS04545"
                     /old_locus_tag="HMPREF0298_1212"
     CDS             complement(8548..10062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015401327.1"
                     /locus_tag="HMPREF0298_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1212"
                     /product="alpha-(1->6)-mannopyranosyltransferase A"
                     /protein_id="WP_083789512.1"
                     /transl_table=11
                     /translation="MARLRTRCVIWRFGRRSAVPRSVWLGLAAGIVIALGSYGAGATRN
                     RGGVMRELGLGHLMYGHGRSIMDALLTAGIIALVVAWVWFGRDLTRQHAGEAETKRATW
                     LWAAGLAFAAPILSRDVYSYLMQGAMLRDGFDPYTEGAAVNPGPYLYEVSHDWRNTTTP
                     YGPLHLWIGERITTLVGDNVTLGILAYKLLTLAGFAAIVWAVPRIAAELGGNPALALWL
                     GVANPVMLLHMVGGMHNEAIMVGLVSVGLLACLRNRFVLGIVVISLAVSLKATAAIALP
                     FVVWMAYNRRRSDTATLARNAVDFVLVGAVSVVLTMAVLWAVTVLSGSSFGWVAEISGN
                     SKVVNPLAGPTLVADAFTPLAQLFDEHFRYNAALALARRIGAVLMLVGLALTWFIFRRN
                     DREAVAGIACAYAVAFVANAVTFPWYYASLLSLLGTVSTPLWVRRATVFFSVVVALAFT
                     GSGNHRFYDGWFIVVSFAAAWIAAEVVYPRAPTTPAEARTPSPALA"
     gene            complement(10001..11095)
                     /locus_tag="HMPREF0298_RS04550"
                     /old_locus_tag="HMPREF0298_1213"
     CDS             complement(10001..11095)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018016745.1"
                     /locus_tag="HMPREF0298_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1213"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_040422676.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.8e-48, bitscore:
                     158.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAREDANPADFPSAVKGALEAFLDERYAEVEKIGPPVTRSVQHLR
                     DFILGGGKRIRPLYAWTGFFGARAAGGVGSEDPEAVLRAVSSLELIQACALIHDDIIDA
                     SDTRRGNPTVHRAVEARHSKDDLFGDSADYGRNEAILIGDFALIWAEDMWRYSGLSEAA
                     LTRAAEPWRGMRTEVIGGQLLDIALEAAANESVEMANNVNRYKTAAYTIERPLHLGAAI
                     AGAPADTIEAFRGYGRDIGIAFQLRDDLLGVFGDEAVTGKPAGDDLREGKRTVLLAAAL
                     NRLDATDPVSAARLRDRVGRTSDRDELAELAAIVESSGAIADVEKQIADLTESGLAHLS
                     RAGIDGEVANTLRDLAIRATERRA"
     gene            complement(11159..11776)
                     /locus_tag="HMPREF0298_RS04555"
                     /old_locus_tag="HMPREF0298_1214"
     CDS             complement(11159..11776)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005324493.1"
                     /locus_tag="HMPREF0298_RS04555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1214"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_006839940.1"
                     /transl_table=11
                     /translation="MTVTYRRLSGPEFAILAPDLVDIYITAMGYDPAIRSGRISVWQRE
                     IVWPGFTAVAAIERTATAAGSMGGAVDGAVDETVVGIAYGFIGSRERWWDQQLIRGLRQ
                     NGGISPQHSAMLRDYFEIAEIHVHPSRQGAGIGRALLSRLLWNAPARWALLSTPEVANE
                     SNNAFGLYRSMGFRDILRDFYYAGDDRPFAILGRTLPLHAGG"
     misc_feature    complement(11837..11851)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.1"
                     /tool="antismash"
     misc_feature    11838..11851
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.84"
                     /tool="antismash"
     misc_feature    11838..11852
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.08"
                     /tool="antismash"
     misc_feature    11869..11884
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.67"
                     /tool="antismash"
     misc_feature    complement(11870..11883)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.51"
                     /tool="antismash"
     gene            11936..12376
                     /locus_tag="HMPREF0298_RS04560"
                     /old_locus_tag="HMPREF0298_1215"
     CDS             11936..12376
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018580619.1"
                     /locus_tag="HMPREF0298_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1215"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_006839941.1"
                     /transl_table=11
                     /translation="MSSIVSATTKATYGAAAHGTRREQFFRSAHVLLAQARTDYEAGAL
                     DMAMENAYRAALRAAGAVNAGSPVIRKRKRLPASAWDKLALTSDRGKEWASTFSAFSAP
                     RNRAITGIEPNPDANVVLRLIALVEEFLEESTPGSTKAPLVA"
     gene            12505..12891
                     /locus_tag="HMPREF0298_RS04565"
                     /old_locus_tag="HMPREF0298_1216"
     CDS             12505..12891
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005324498.1"
                     /locus_tag="HMPREF0298_RS04565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1216"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_006839942.1"
                     /transl_table=11
                     /translation="MSLSEQEQRTLREIEQSLLAEDPKFGDRVPQGSGFAGQAGGGRLT
                     MRSAALMVTGLVLLIGGVALATVSVWLVAVSVIGFIVMLAGGVMALTTPSGESSPQPRP
                     VAATRRPARSSKMEENFKRRFEGQ"
     misc_feature    complement(13101..13115)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.41"
                     /tool="antismash"
     misc_feature    13156..13170
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.85"
                     /tool="antismash"
     gene            13333..13767
                     /gene="mraZ"
                     /locus_tag="HMPREF0298_RS04570"
                     /old_locus_tag="HMPREF0298_1217"
     CDS             13333..13767
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0051302 - regulation of cell division
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mraZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013911875.1"
                     /locus_tag="HMPREF0298_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1217"
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="WP_006839943.1"
                     /transl_table=11
                     /translation="MFLGTYTPKLDDKGRLTLPAKFREDLADGLMVTKGQDHSLAVYPR
                     EEFAARARKAAAASRTNPKARAFIRNLAASADEQTLDGSGRITLSPAHREYAHLSKECV
                     VIGSVDFLEIWDAESWANYQQETEAAFAAADDDDILSGLL"
     gene            14009..15010
                     /gene="rsmH"
                     /locus_tag="HMPREF0298_RS04575"
                     /old_locus_tag="HMPREF0298_1218"
     CDS             14009..15010
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015651693.1"
                     /locus_tag="HMPREF0298_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1218"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_040422678.1"
                     /transl_table=11
                     /translation="MDFRVDPNHGHVPVMRDRMADLLAPAVEVFGAGAVIVDATLGAGG
                     HTEHFLRRFPGASVIGVDRDPAALRDATERLAPFADRFVGVQARFDDIGTAIRDRDGAI
                     FDAARTHGVAGALFDLGVSSMQLDQEERGFAYKVDAPLDMRMDPTTTLTAADVLNTYSH
                     GELARILKTYGDERFAGKIASHILKEREKAPFERSARLVELLYQAIPAATRRTGGHPAK
                     RTFQALRIEVNGELDALRAVIPVITDLLGPGGRAVFMSYQSLEDKIVKNALTSLTTSTT
                     PTGLPMDLPGTAATFRWITHGAEKASEAEIDQNSRAAPVRVRGVEKLRTDNP"
     gene            15011..15802
                     /locus_tag="HMPREF0298_RS04580"
                     /old_locus_tag="HMPREF0298_1219"
     CDS             15011..15802
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018297087.1"
                     /locus_tag="HMPREF0298_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1219"
                     /product="hypothetical protein"
                     /protein_id="WP_006839945.1"
                     /transl_table=11
                     /translation="MTMMTTTKGSNAMGASRDLTAAARSGTATLERPAVRRPRTTTPRT
                     TATPQPVRRYAPHALHPRNTQGVGRLGSKQVVSVRGRRVGEVSEIKRTFSTMSVIAVPL
                     LILGVLIAMFLSGLSTSQSFTIQELQSRERALSNEVETLNRDAENAKSSAEIARKAADA
                     GMVVSHAPGILSVGADGAVEETRPFDPEATQKIDDVTSAGGQRGTEDRATSDRDATARV
                     SDSLTSVPGGNVLDQGNPPAPEAAPLANNLAPYAPRVATGN"
     misc_feature    complement(15012..15026)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(15855..15871)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.43"
                     /tool="antismash"
     gene            16020..17894
                     /locus_tag="HMPREF0298_RS04585"
                     /old_locus_tag="HMPREF0298_1220"
     CDS             16020..17894
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018016752.1"
                     /locus_tag="HMPREF0298_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1220"
                     /product="penicillin-binding protein 2"
                     /protein_id="WP_157464398.1"
                     /transl_table=11
                     /translation="MTRKRASFIAAVFIVAAVVLVGRLAWVQIVWGPDLQTQAEAQRAR
                     VYIDPARRGEIIDRSGNQLAYTMQARSLTVSPVMLRKELREQQEGQVSVDGLSDDVIQA
                     QVDARVEDVLRTMANEIPRMIEGAHATDPAAAQARVSSKDILDKLHADSNYEVLVRNVD
                     PDVATKVAKKFHGVAADHQDIRQYPNGAVGENIVGKVSMDGQGQFGLEASSDSVLTGIN
                     GRSTEDVSADGQSIPGTLRDVVPAVDGSQVKLTIDVDLQTFVQRTLEQAKANSLAKDAE
                     AVVLDAHTGEVLAMANTGTIDPNGDLQKQLAEGRSFDNNSISHPYEPGSVAKVITAAAA
                     IEEGLTNPTEVHQVPGSIDMAGVTVKDAWSHGVAPYTTAGIFGKSSNVGTLQIAQRLGE
                     DKYWDYLQRFGIGQSTGIELPNESAGLVPVLEQWSGGTFANLPIGQGMSWTTLQMASVY
                     QTLANGGERIEPRIISEVIGPDGQSMEADAPARTRVVSEATAKTTVDMFRSTFQQDPMG
                     VNSGTAQGNEIEGYQLAGKTGTAQKVNPETGAYTQNQFWITFAGVAPADDPRFVVAVML
                     DEPQRGPLEGGSGGQSAAPVFREIASWLLNRENIPQSPPSEPYVLEQR"
     gene            17960..19597
                     /locus_tag="HMPREF0298_RS04590"
                     /old_locus_tag="HMPREF0298_1221"
     CDS             17960..19597
                     /EC_number="6.3.2.13"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018580613.1"
                     /locus_tag="HMPREF0298_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HMPREF0298_1221"
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="WP_006839947.1"
                     /transl_table=11
                     /translation="MDHRNENSAAGAPQAPVPLHELARIAGADVASSADNGWAGVAISS
                     VGLNAREVAPGGLFAALPGTRVHGAQFAAESPARAILTDREGLDIVEAAGDRRPVLVVD
                     DVRAVLGEVSAHVYGHPSRRMTLIGVTGTSGKTTTTYLLERGLIAAGAQVGLIGTTGTR
                     IRGRDVPTSLTTPEAPTLQALFARMAAEGVTHVVMEVSSHALSLGRVDGTSFDAAGFTN
                     LSQDHLDFHPTMDDYFQAKAAFFDPSSPVAASASVVCVDDEWGERMAELASHPLRVGTH
                     GQEGLDCSARLTAVRDNGAQDIELRIDGQTHEFTLPLPGAFNVANAALATALARVVGAD
                     MPQFVRGLENAAVPGRMERIDAGQDFVAVVDYAHKPAAIAAVLETLREQVDGRIGIAVG
                     AGGDRDTTKRAVMGQQAATRADLVIVTDDNPRTEDPAAIRAAVLRGAREAGSGAEIREC
                     GPRAEAIDQLVAWALPGDAIVVVGKGHEVGQIVGDTTHHFDDREEMRRALADNGYGEND
                     AHGTHQPDGLHGPQELADGKDFFAHDPT"
     misc_feature    20255..20275
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.04"
                     /tool="antismash"
     misc_feature    20460..20475
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    complement(20628..20641)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.61"
                     /tool="antismash"
ORIGIN
        1 cacccaccgg tgacgtcgca gctgcaatcg cggcagtcaa ggctgtgccg ggcgtaacca
       61 acatcccggg cttctccgac ttcctcgcgg aggctgagac ccgctacgcc accgccccgg
      121 ctgacacgtc cgcgcagacc gtcgaagctg ctgcggcacc ggcaatcgtc gctccggcac
      181 cctccgctgg ccagcagatc gttgacatcg cccgctccaa gatcggctcc ccgtacgtct
      241 acggcgcggc cggccccaac gccttcgact gctccggttt cacctcctgg gtccacgcac
      301 aggctggtaa gtccatcccg cgtacctctc aggcgcaggc ttccggcggc acccccgtca
      361 gcctgaacga catccagccg ggcgacgtcg ttgtctacta cagcggcgcc tcccacgtcg
      421 gcatctacgc cggcaacggc accatcatcg acgctttaaa ctccggctcc ccggttacgg
      481 agcgcccgct caacatgatg ccgatccact ccgtggttcg cttctaaacg cattctcaaa
      541 ctggccccgc gcgacggcgt gcggggccag ttttgcgcct caaaacaaat cgggggcaat
      601 gtcttgattc tcgggttcgg ggcgctatag tgtgtaacag ttctataaag ctcgagctgc
      661 ttagctgcgg ctccagcgcc gtgtccgttg cggatgcggc ccatatcctg ttaaagggtt
      721 ttacaaggaa agtgtcgagg aagtccaccg tgggtaagca ctctcttcct ccgcgcgctc
      781 gccgaagcgc cggaacaatt gcatacacaa ccgtttccct ggccgtcgcg ggtgccaccg
      841 tggccggact cgtttctccc gcacacgccg aagacctgga caccctcatt gcggaactag
      901 gtaccgtctc ggacgaagcg accgcgaaga tggagcagat taaggacctc gagggccagc
      961 tcgagcaggc gcgtgcggag ctcgatgata gcgctcgggc ggccgctgct gcccaggcta
     1021 gggccgagga ggtgcgtgga gcccgcgcca tgcagcaggg ggacgtcaac gctgtcgcga
     1081 cttcgaccta ccgcacgctg caggtggaca atgtggtgaa cacgctcggt tccgctaccc
     1141 cgcaggaggt cattgacaag accacctacc tcggatccat ttcccgcaag cgccaggagc
     1201 agcttgatgg cctgcgcgcc gcgaacgaag aggcgattca ggccgcgcgt gaagcggacg
     1261 tcgctaaggc gaccgcgcag tacaaccgcg tcaagctcga cacacagttg gcgcagctgg
     1321 aaaaggagcg tgctgacatc gaggcccgga tcaaagacgt tgaggcccgt gtggatgcgc
     1381 tctcgcccgc ggcgcgtgag gcttggacga accaggccaa cccggtgcct gcggacatgc
     1441 ttgacccggg tgcgttcggt aacgcgatca cggccgctgc gctcgcgcag ctgggcaagc
     1501 cctacggctg gggggccgcc gggcccgatg ctttcgactg ctccgggctg atggtgtggg
     1561 cgtactccca gaacgggaag tcgatcccgc gcacctccca ggcgcagctt gctggcggaa
     1621 cccccgtgtc catgtcggac ctgcaaccgg gtgacatcgt cggctactac ccgggtgtca
     1681 cgcatgtggg catgtacatc ggcaacggcc aggtcgtcca cgcatccgac tatggcatcc
     1741 ccgtccaggt cgtgccgttg aactcgatgc cggtgcaggg agcggtccgc tactagaatg
     1801 ccggtgctgc tcgtcactaa cgacttccca cccgctgtcg gtgggattca gtcgtatgtg
     1861 agggacttcg ccgatgagtt cgtgcggagg gccggccccg acgagctcct cgtgttcgcc
     1921 tccactcaag acgccgacgc ggctaggcgc tgggactcga acgttggcta caccgtggtg
     1981 cgctggccgc gccgcgtcat gctccccacc ccggcgacgg tccgcgagat gcgccgcctc
     2041 atccgcgaac acggcgtgga caccgtatgg ttcggagccg ctgcgcccct ggcgctgatg
     2101 ggggcggcgg cgaagtcggc tggagcgcgg cgggttctcg cctcgaccca cggccatgag
     2161 gtcggctggt cgatgctgcc tggcgcgcgt caggtgctct cggtcatcgg gcggcgcgcg
     2221 gacgtggtga cgtacgtgtc ggagtacgct gtcgggcgct tccggagcgc gtttggggcg
     2281 atgccgaggt tcgaggcgtt gccgtcgggc gtcgacaagc aattttttcg cccggccagc
     2341 gagcccgagc gtgccgccgt gcgctccgag ctgggcatcc gcgggccgat gattgtttgc
     2401 gcgtccaggc tcgtgcgccg caagggccag gacacgctta tcgacgccct ccccagcatc
     2461 atcgatgcct accccgacgc acgcctcgtc atcgtcggcg aggggcccta cgcacgcgcc
     2521 ttgacaaggc gcgcgagacc gctcgccgaa tccgtggtgt tcaccggagc cgtggatcgt
     2581 gcgcgtctgc gcgacatcgt cgcggcggcg gacgtgttcg cgatgcccgc gcggacgagg
     2641 ggagcgggcc tggacgtgga ggggctcggc attgtctacc tcgaagccca ggcgtgcgcc
     2701 gtgccggtcg tggtggggga ttcgggtggg gcgccggaga cggtgacgga tcaaaccggt
     2761 gtcgtggtcg acgggcgaga ccacgacgcg gtggccgctg cgatcatctc cctgctgggg
     2821 gatcctgcac gacgccgcga gatgggccga gccggccgcg cccacgtgga gcgggccttt
     2881 tcgtgggaag ccttgggaga caggctctac aaccttctga gcccgacggg ttaatatagt
     2941 tggctatgct ccccgaaacc cgacgcgcgg acgccgcgcc gttgaccatc ggcttcgata
     3001 ttggcggcac gaacacccga gctggcgtgg tcacggccgc cggagagatc atcgactcgc
     3061 gctcgattga aaccccgcac gacgcagatg agctcaccgc gtcgattacc cggctcgtcg
     3121 ccgaggtgcg ccgtgaccac gacattgcgg cggtcggtgc ggcgatcgcc gggtttttgg
     3181 accccgcctg cgagaaggtg cgctttgccc cgcacttgcc ctggcgtaac gacgctcccg
     3241 tcaaggccat gctggaagac gcgatcggtc tgcccgtgcg cctcgagcac gacgctaact
     3301 ccgcggcgtg gggggaatac aagttcggcg cggcgaagaa cgccgagacg tgggtgttct
     3361 tcgccgtcgg cacgggaatc ggcgccacgc tgatgcaccg cggcgagatc taccgcgggg
     3421 cgttcggcac ggccccggag ttcgggcacc tcaccgtcgt gccgggtggg cgggtgtgct
     3481 cctgcggcaa acacggctgt ctggagcgct acgcctccgg cacggctctg gtggataccg
     3541 ccgtggaggt cgcctccgcc ggcgggtaca aggcgtgcgg gctctaccgc aaagtagtgg
     3601 acaagcgcgc caacgggcac gacgtgatgg ctgcggcgcg gagcggggat gcgctggggc
     3661 gggcggccgt cgacacgttc gcggactggc tcggccaggg gctctccatc gtcgccgacg
     3721 tgctcgaccc cgagctcatc gtgctgggcg ggggtgtcag cgacgacgcg gatctcttca
     3781 tcgaccgggc gaggggtgcc atgacccgcg acatcgtggg cgccggctac cggccgctgc
     3841 cgacactcat tcgcaccgag ctcggccccg aggcaggtat gatcggcgtg gctgatttgg
     3901 cgcggaaact ggtgtaaagg aaaagcacat ggtgaacaaa tggtatgcgg tgttcaaggc
     3961 catcctaggc ccgccgttgc tggtgtggaa ccggccgacg atcgagggcg cgcacaacat
     4021 tccgcgcaca ggcaccgcca ttttggcgtc gaaccaccag gccgtgatgg attcgttcta
     4081 cctcccgctg atggtgtggc gccagctcac gttcccggcg aagaaggaat acttcaccac
     4141 cccgggtgtc ggcggagcga tccagcgctt cttcttcagc tcggtgggcc agatcccagt
     4201 agatcgcagc tcctccgggg ccgcagacga cctggagcgc gcggcggagg aggtcttcgc
     4261 cgacggaaag ctgatggggt tctaccccga gggcacccgc tcgccggacg ggcgcctgta
     4321 caaggggcgc accggcatgg cgcgtatcgc gatgaaaaac aacgtcgacg tcatcccggt
     4381 ggcgatgatt ggcacccgca acgccaaccc gattggcacc ttcgttccgc gtccccggcg
     4441 ggtgcgcatc aaggtcgggg agccgatcag cccgcacgcg tgggcgcgcg agaacggttg
     4501 cgaccccgac tcccgtgagg tggcgcgccc gttcaccgac ttcatcatgg aaaagctcag
     4561 tgagctgtcg ggctacgagt acgtggacgc atacgcgtcc gaggtgaaga agtcgctcga
     4621 ggccggccac ggctaccccg cgggtacgga acctaagacg ccgtaattta agatggtggc
     4681 catggaccga gaccttctca tccgcgtggc cttatgctgc gtgctcgtcg ccgcagtcat
     4741 ggtggccacc cagaccggcc gctacatcaa cgttgtcgcc ccgctcgcgg tgatcggcgt
     4801 ggcggtggtc atgttctggc cgcgccgacg cggggcatcc gccccggatc ccgcggagcg
     4861 cgatgacgcg tccgggcgtg ggtagggtgc gctacttcta cgacaccgag ttcatcgagg
     4921 acggcgctac catcgagctg gtctccatcg ggattgtcgc cgaggacggc cgcgagtatt
     4981 acgcggtgtc gacggacttc gacgcggcca aggcgaaccg gtgggtgcgc gacaacgtcc
     5041 tggacaagct tcccagcccc ggggagtccg agtggaaacc gaactccgcg atccggcgcg
     5101 aggtgctcga gtttgtcacc gccgggccgg gccacccgga gctgtgggcc tgggtgggcg
     5161 cctacgatca tgtggtcctg gcccagctgt ggggcgacat gagcgcgctt cctaaggcgc
     5221 tgccgcggta cacccgcgaa ctgaagcagt actgggagat ggcggggcgc ccgaagctgc
     5281 ccagtttgcc caagggcaac cacaacgcgc ttgtcgacgc ccgccacaac ctggccaagt
     5341 tcaccgcctg taccgcggcc ctgccgctgg gcgacaatgg gcaggtttcc atcgtgcggg
     5401 aacaccattc caccaggtga caatcgcctc ccgtgacctg gggtttcaaa tatgccccca
     5461 gcatgataaa acttgagggg tgagttggac tatcgacatc cccaaagacg ttctgcccga
     5521 tcttccgccg ttgccggggg atttgaacga acgattccag gacgtcatct cccgtgacgc
     5581 caaacagcag ccgacgtggg acgcgaacga ggccggctac gtgcgcaaga tcctcgagtc
     5641 cgttccgccc gtcgtactcg cacccgagat cgaggtgctc aagggccagc ttgccgacgt
     5701 cgccctgggc aaggcgttcc tcctgcaggg cggcgactgc gccgagacct tcgaatccaa
     5761 cacggagccg cacatccgcg ctaacgtgcg caccctgctg cagatggcgg ccgtgctgac
     5821 gtatggcgcc tcggtgcccg tggtcaagct cggccgcatc gctggccagt acgccaagcc
     5881 gcgctcgtcc gacctggacg aaaacggact gccgaactac cgtggcgaca ttgtcaacgg
     5941 tgtggagccc acccctgagg accgccgaca cgaccccgcc cgcatggtcc gtgcgtacgc
     6001 gaacgcctcg gcagccatga acttggtgcg tgcgctgacc tcgtcgggca cggcggatct
     6061 gaaccatatc cacgactgga accgccagtt cgtggcgtcg tcgccggctg gtgcccgcta
     6121 cgaggcgctg gcgcgcgaga tttcgcgctc gctcgatttc atgcgcgcct gcggtgtcaa
     6181 cgacgagcac ctgcgcacca gcgagatcta cgcctctcac gaggcgctgc ttgtggacta
     6241 cgagcgcgcc atgctgcgcc tcgcggagga ctcccacgga gaaaccaagc tctacgacct
     6301 ctccgcccat cagctctgga tcggtgagcg cacccgtggc atggaggact tccacgtcaa
     6361 cttcgccgcg atgatcaaca acccgatcgg gatcaagctc ggcccgaagg ccacccctga
     6421 ggaagccgtc gcgtacgccg agaagctgga tccgaaccgc gagccgggcc gacttaccat
     6481 ggtcattcgc atgggccatg acaacgtccg cagcgtgctg ccgggcatcg tcaaggccgt
     6541 cgaggcctcg ggccacaagg ttgtctggca gtccgacccg atgcacggca acaccttcac
     6601 cgcgtccaac gggtacaaga cccggcactt cgacaagatc attgatgagg cccagggctt
     6661 cttcgaggtc caccgcgagc tcggcaccca cccgggcggc gtgcacatcg agctcaccgg
     6721 tgagaacgtg accgagtgcc tcggcggagc gcaggacatc accgacctgg atttgccggg
     6781 ccgctacgag tccgcttgcg acccgcgcct gaacaccgag caggccctgg agctggcctt
     6841 cctcgtggcc gagatgctgc gctactaaaa gcgcccggtt aaaaactttc gcccagttct
     6901 ccccgcccta tctaatgagg gcggggagtt cgccgtacat gcccgagccg aaccaccacg
     6961 cgccgatggc cactagcgcg atgaccagca gcgacagcgc cacgaagatc gcggtgccaa
     7021 gcgcgctgcg attggtcaac ggcttcggcg gtggggcaac tggcggtggg gcaactggca
     7081 caggggaggg tgccgcaggc ggcggagctg ccggcaccgg ggtcaccggg ggttgtggcg
     7141 cggccccggc cacgcgggtg ctacccgatt cgggaaacag gcgtcgctca aacgcgggcg
     7201 gtgcgggctg cggctgcggg gtgttcagca acgtgacagc cgtcgggtgg gccgctgcgc
     7261 ggttcgcggc ggagtcgcgc ggcaccggca ccacgtagtc gggcaggcca agcgccgcgg
     7321 cgacgtcgtc aagcgcggcg aggaactcgg cagcgtcgac gaagcggtcc tcggggcggc
     7381 gggaggttgc tgtcgcaacg agctcgtcga caagcttggg cacgccctcg atgcgtgacg
     7441 acggcgccgg gacgtcccgg ttgagccgcg cgtacgcatg agccagcgga gtctcgcccg
     7501 agaatgggac acctcccgtg agcagctcga acaagacgat gccggcggag tagacatcag
     7561 aggccgggcc catcggggaa ccatcgactt gctcgggcga aagatagctg acagtgccca
     7621 cgatctgatc ggttgagtga gtggcatcgg cagcagcacg cacgaggccg aagtcggcaa
     7681 gtttcacgcg gtggtctaag ttgatcagaa tgttgtccgg cttgatgtcg cggtgcacca
     7741 ttcccttgcg gtgggcgatc gagagcccgg tcagcgtcgc gcgcatgacc gcggcggctg
     7801 cgtgcggggg catcgggccg cgctcggcca gcaactcgcg cagcgtgccg ccgcgaatca
     7861 gctccatgat gaggaaaacg tggtcgccct cgtgggaaaa gtcgtagacg ttgaccaggt
     7921 tggggtgcga cagctgagcc atggcgcggg cttcgcgccg gaagcgggta agaaagagat
     7981 gatcgtcgac gtagcggttg tccatcacct tcgccgcgac ctccctaccg aggcggacgt
     8041 cgacgcagcg gtacaccgtg gacatgccgc cgcgggcgat ggggcgatcg atgacgtagc
     8101 ggttgtccag ataatcaccc acggcaagct cagtcatgca ttccagtatg gccgacaggc
     8161 gcctccaaca gccaacccac agccagtgcg cgggtaaggt atctcacgtg actacgccga
     8221 atattgacct cgacggattg ctcgccaacg agacacttct gccgctgccg gatgtcgccg
     8281 agtacctcgg cgtgccggtg accaaggtgc acgacctcgt gggtgcgcac aagctgctcg
     8341 tctaccgcaa agacggggtg aagtacgtcc ccgagcgcct cttaggcgag gacggggagc
     8401 tgtccaagtt cgtcggcggc gccatcatgg tgcttcacga cggcggctac agcgccgacg
     8461 agatcctcca ctacctgttc accgacgacg agtcgctgcc cggccggccc atcgacgccc
     8521 tgcacagcca cggcgcacgt gaggtgatca ggcgagcgca ggcgatggcg ttctagcctc
     8581 agccggcgtt gtcggcgccc gcgggtagac cacctcggcg gcgatccagg cggcggcgaa
     8641 ggacacgacg atgaaccagc cgtcgtaaaa gcggtggttg ccgctgccgg tgaaggcgag
     8701 agcgaccacg acggagaaga agaccgtggc gcgccgcacc cacagcggcg tactcaccgt
     8761 gcccagcagg gagagcagcg aggcgtagta ccacgggaag gtcaccgcgt tggcgacgaa
     8821 cgccactgcg taggcacacg cgatgcccgc caccgcctcg cggtcgttgc ggcggaagat
     8881 aaaccacgtc agagccaggc cgacgagcat cagcaccgcg ccgatccggc gcgcgagtgc
     8941 gagtgccgcg ttgtagcgga agtgctcgtc aaaaagctgg gcgaggggag tgaacgcgtc
     9001 ggcgaccaag gtggggccgg cgagcgggtt gaccaccttt gagttcccgg agatctcggc
     9061 gacccagccg aaggaggagc cggagagcac agtaacggcc cacagcacgg ccatggtcag
     9121 cacgaccgac accgcgccga ccagcacgaa atcgacggcg ttgcgcgcga gggtcgcggt
     9181 gtcactgcgg cggcggttgt aggccatcca caccacgaac ggcagggcga tcgcggcggt
     9241 ggctttgagc gacaccgcga ggctaatcac cacgatgccg agcacgaaac ggttgcgcag
     9301 gcaggcgagc aggcccacgc tgacgagccc gaccataatc gcctcgttgt gcatcccgcc
     9361 gaccatgtgc agcagcatca ccgggttggc cacgccgagc cagagcgcga gggcggggtt
     9421 gccgccgagt tctgcggcga tgcggggcac ggcccagacg atcgccgcga acccggcgag
     9481 ggtaagcagc ttgtacgcca ggatccccaa ggtgacgttg tcgccgacga gggtggtaat
     9541 ccgctcgcca atccacaggt gcagcggccc gtagggggtg gtcgtgttgc gccagtcgtg
     9601 gctgacttcg tagaggtagg ggcccggatt gaccgcggcg ccttcggtgt aggggtcgaa
     9661 gccatcgcga agcatcgcgc cctgcatgag gtaggagtag acgtcacgcg acaggatcgg
     9721 cgcggcgaag gcaagcccgg cggcccatag ccaggtcgcg cgcttggtct ccgcctcgcc
     9781 cgcgtgttgg cgggtgaggt cgcgcccaaa ccagacccac gccaccacta gggcaataat
     9841 gccggcggtg agcagcgcgt ccatgatgga gcggccgtgg ccgtacatga ggtggcccaa
     9901 gccgagctcg cgcattacgc cgccgcggtt gcgggtggcg ccagcgccgt agctgccgag
     9961 ggcgataaca atccccgcgg cgaggccgag ccataccgac ctaggcacgg cgctccgtcg
    10021 cccgaatcgc cagatcacgc agcgtgttcg caacctcgcc atcaataccc gccctgctca
    10081 agtgggcaag cccggactca gttaagtccg caatttgctt ttcgacgtcc gcgatcgcgc
    10141 cgctggactc cacaatcgcc gcgagctccg caagctcgtc gcgatcgctc gtgcggccca
    10201 cgcgatcgcg caggcgggcg gcggagacgg ggtcggtggc gtcgagacga ttcagcgccg
    10261 cggcgagcag gaccgtccgc ttgccctcgc gcaggtcgtc gccagccggc ttgccggtga
    10321 cggcttcgtc gccgaagacg ccgagtaggt cgtcgcgaag ctggaaggcg atcccgatgt
    10381 cgcggccgta gccgcggaac gcctctatcg tgtccgctgg cgcgccggcg atcgcggcac
    10441 cgaggtgcag cgggcgctcg atggtgtagg cggccgtttt gtagcggttg acgttgttgg
    10501 ccatctcgac agactcgttg gcggcggcct cgagcgcgat gtcgagcagc tggccgccga
    10561 tgacttcggt gcgcatgccg cgccacggct cggcggcgcg ggtcagcgcg gcctcgctga
    10621 ggcccgagta acgccacatg tcttccgccc agatcagtgc gaagtcgccg atgaggatgg
    10681 cctcgttgcg cccgtagtcc gccgagtcgc cgaacaggtc gtctttactg tggcgggcct
    10741 ccacggcgcg gtgcactgtg gggttgccgc gccgggtatc ggaggcgtcg atgatgtcgt
    10801 cgtgaatcag cgcgcacgcc tggatcagtt cgagcgagct cacggcgcgc aggacagcct
    10861 ccgggtcctc ggagccaacc ccgcctgcgg cgcgcgcgcc gaagaagccg gtccaggcgt
    10921 acagggggcg gatccgcttg ccgccgccga ggatgaagtc gcgcaggtgc tgaacggagc
    10981 gggtgaccgg ggggccgatc ttctccacct cggcgtagcg ctcgtcgaga aacgcctcga
    11041 gcgcaccttt gacggctgaa gggaaatcgg ccgggtttgc gtcctccctg gccaacccgc
    11101 tcggcgcacc caccacaacg atctcctcat tacctatcga caatatttcg cctcaacact
    11161 acccgcccgc gtgcagggga agggtgcggc cgaggatggc gaaggggcga tcgtcgcccg
    11221 cgtagtagaa gtctcgcagg atgtcccgaa agcccatcga gcggtacagg ccgaacgcgt
    11281 tgttggattc gttcgcaacc tcgggggtgg acagcagggc ccatcgcgcc ggggcgttcc
    11341 acagcagacg ggaaagcagg gcccgcccga tccccgcacc ctggcgggag gggtggacgt
    11401 ggatttcggc gatttcgaag taatcacgaa gcatcgctga gtgctgcggg cttatcccac
    11461 cgttttgacg caggccacgg atgagctgtt ggtcccacca ccgttcgcgg ctgccgataa
    11521 atccgtacgc gatgccgact accgtctcgt caaccgcccc gtcaaccgcg ccgcccatgc
    11581 tgccggccgc tgttgctgtg cgttcgatgg cggcgacggc agtgaaaccg ggccagacaa
    11641 tctcgcgctg ccagacagaa atgcggccag agcgaatcgc cgggtcgtat cccattgccg
    11701 tgatgtagat gtcaacgagg tcgggggcga gaatcgcgaa ttcggggccg ctgaggcgac
    11761 gataagtcac agtcaccctt ctatcgaacc atgcggcgca cacgaagtgg tggtgttcgg
    11821 gacacaatga cccgattaga acaaatgttc caacattgcc ggggtatgtc gaacgtgcgt
    11881 tttagagtat cggcaatcaa caagattaaa cgacgcacaa ccccgggagg tacacatgtc
    11941 cagcatcgtc tcagccacca cgaaagccac ctacggagct gccgcgcacg gaacccggcg
    12001 tgaacagttc ttccgttccg cgcatgtgct tcttgcccag gcgcgcaccg attacgaggc
    12061 gggcgccctc gatatggcaa tggaaaacgc ctaccgcgcg gcccttcggg cggcgggagc
    12121 tgtcaacgcc ggctcgccgg tgatacgcaa acgcaagagg cttccggcta gtgcgtggga
    12181 caaactcgcg ttgacgtcgg atcgtggcaa agaatgggcc tcgacgtttt ccgcgttttc
    12241 cgccccgcgc aacagggcca tcacgggcat cgaaccaaac cccgatgcca acgttgtgct
    12301 ccgcctcatt gcgctggtag aagaattctt ggaagagtcc acccccggct ctacgaaggc
    12361 acccttagtt gcctagcgtg aacttggtag tcgggtgcgc atttcggaaa ggaaacctcg
    12421 ggtaggaaca atctggatac actggccgtt gtagtagatg taagccaagc acaatcgtcc
    12481 aacggtagag ctggagagta gacagtgtcc ctttctgagc aggaacagcg cacccttcgc
    12541 gagatcgagc aatcgcttct cgccgaggac cccaagtttg gtgacagggt gccccagggt
    12601 tccggtttcg caggccaagc aggcggcggc cgactcacca tgcgcagcgc cgcgctgatg
    12661 gtaaccggcc tggtcctgct cattggcggc gttgcactgg cgacagtgag tgtgtggctc
    12721 gttgccgtca gcgtcatcgg gtttatcgtc atgctcgccg gcggcgtgat ggctctgacc
    12781 actccttcgg gcgaatcctc gccgcagccg cgccccgttg ccgcaacgcg gcgtcccgcg
    12841 cgcagctcga agatggaaga aaatttcaag cgccgtttcg agggtcagta acttactggc
    12901 ggcaccaagc ccgccccgcg cacgcgcgtg gggcgggctt tttcttaccc accgaccccc
    12961 accttctcct cccactttct cccactctcg cggtactcct gccgccccag ggccgtgatc
    13021 tgcggtaaca cctggggaag ctggtatttc agtgctgtct agagaattgg agtggctgat
    13081 gtgaaccgcg tttcaagcga gggaaccgat tttcaggggt agatccacca ccaatttttg
    13141 ttccgttaac ctgcgatttt ccagaagttt tgcgacagga cgcgcctggg tgtggcgttt
    13201 gtgggggaaa gtgggataga gtggggcgca gcggagggcc gcggtggcat cttgactacg
    13261 tgcaaccacg attcgccgct tcggaaaagt tgaacagccg tagtcacaga gtgaaggaag
    13321 gtgggctttc ggatgtttct gggaacctac actcccaagc tcgacgacaa ggggcgcctg
    13381 acgctgcccg ccaagttccg ggaggatttg gcggacgggt tgatggtgac caaggggcag
    13441 gaccactctc tggcggtcta cccccgcgag gagttcgcgg cccgtgcccg caaggcagct
    13501 gcagcttcac gcacgaaccc gaaggcgcgc gccttcatcc gcaacctggc tgccagcgcg
    13561 gatgagcaaa cgctcgatgg ttccggtcgc atcacgctgt cgccggcgca ccgcgagtac
    13621 gcacacctgt ccaaggagtg cgtggtcatc ggctcggtcg attttctcga gatctgggac
    13681 gccgagtcct gggctaacta ccagcaagaa accgaggctg ccttcgcggc agctgatgac
    13741 gacgacattc tctccggcct cctgtagggc tgactacccc gcaggcaggc gctgaccaac
    13801 tgcggagagc gtgtacggac tctgtccgtg gcgtggagcg ttctggtgta cttccccgac
    13861 accagaacag ccgcctcggg cagggcccta tacgttcccc gaccgagaca cagcacgaca
    13921 caccgcacga caaccgcgca cgacggccag ccaaaccaag ggggtggatc caatggcaca
    13981 caaggacaac gctgctcaca tcgcggatat ggactttcga gtggatccca accacggcca
    14041 cgttcccgtc atgcgggacc gcatggcgga cttactcgcc ccggctgtcg aggtgttcgg
    14101 tgcgggcgcg gtcatcgtcg acgcgacact tggcgcgggc ggccacacag agcatttcct
    14161 gcggcgcttc ccaggggcgt cggtaattgg tgtagaccgc gaccccgcgg ccttgcgcga
    14221 cgcgaccgag cgccttgctc cgttcgccga ccgcttcgtc ggggtgcaag cgcgtttcga
    14281 cgacatcggc accgcaatcc gcgaccgcga cggcgccatc ttcgacgccg cccggacgca
    14341 cggggtagcg ggcgcgttgt tcgacctcgg tgtctcgtcc atgcagctag accaagagga
    14401 acgcggcttt gcctacaagg tcgacgcacc cttggacatg aggatggacc ccacgacgac
    14461 gctgacggcg gcggacgtgc tcaacaccta cagccacggc gagctggccc gcatcttaaa
    14521 aacctacggt gacgagcgtt tcgccggcaa gatcgcctca cacatcctga aagagcgcga
    14581 aaaggccccg tttgagcgca gcgcgcgact tgtggagctt ctctaccagg ccatcccggc
    14641 cgcaacccgg cgtacaggcg ggcacccggc aaagcggacg ttccaggcgc tgcgcatcga
    14701 ggtcaacggc gagctcgacg cgctgcgcgc ggtgatcccc gtgatcactg acctgctcgg
    14761 cccgggcggg cgcgcggtgt tcatgagcta ccagtcgctc gaggacaaaa tcgtcaaaaa
    14821 cgccctgacc tctttgacca catccacaac cccaaccggt ctgccgatgg acttgcccgg
    14881 caccgccgcc acgttccgct ggatcaccca cggcgcggaa aaagcgtccg aggcggaaat
    14941 tgaccaaaac tcccgggcag caccggtgcg tgtccggggc gtcgaaaagc ttcgcaccga
    15001 caacccgtag atgaccatga tgaccacgac gaaaggcagc aacgccatgg gagcaagccg
    15061 agacctcacc gcggcagccc gctcgggcac agccaccctc gaacggccgg cagtgcgccg
    15121 cccgcgcacg acgacgccgc ggacgacggc gacgccgcag ccggtgcgtc gatacgcgcc
    15181 tcatgcgctg cacccgcgca acacccaggg tgttggccgg ctcggctcca agcaggtcgt
    15241 gtccgtccgc ggccgcaggg tcggcgaagt aagcgaaatc aagcgcacct tctccaccat
    15301 gtccgtgatc gcggtgccgc tgctcatcct cggcgtactc atcgccatgt tcctctcggg
    15361 cctgtccacc tcgcagtcct ttaccatcca agagctccag tctcgcgagc gcgcgctgag
    15421 caacgaggtg gagaccctca acagggacgc ggaaaacgcg aaatcctcgg ccgagatcgc
    15481 gcgcaaggca gctgatgccg ggatggtcgt ctcgcacgcg cccggaatcc tgtccgtggg
    15541 tgccgacggc gcagtcgagg agacccggcc gtttgacccc gaggcgacgc aaaagattga
    15601 tgacgttacc tccgcaggcg gccagcgcgg caccgaggac cgggcgacca gcgaccgcga
    15661 cgccaccgcc cgcgtctcag acagcctgac ctccgtgccc ggcggcaacg ttctggacca
    15721 gggcaatcca ccggcaccgg aggctgcccc gctggcaaac aacctcgcgc cgtacgcgcc
    15781 gcgcgtggca accggaaact gaagggcgtg gcgctgccgt acacggggct gcgcggcggg
    15841 caagatgaag tgcgatgtga aacaacaacg aggcaggtga cttaagcgct gtgaataccc
    15901 cgagcgcccg ccgccggccg gagcatcgcg gtgagagcac ccgcgttgac aacctccgcc
    15961 cgcagcccgg cccgcacgcg cccggcccgc agtcgggccc gggcgcgccc cagaaggtga
    16021 tcacgcgcaa gcgcgcgagc ttcatcgcag ctgttttcat tgttgccgcg gttgtgctcg
    16081 tgggtaggtt ggcctgggtc caaatcgtgt gggggccgga cctgcagacc caggctgagg
    16141 cgcagcgcgc ccgggtctac atcgaccccg cccgccgcgg cgaaatcatc gaccgctccg
    16201 gcaaccagct cgcctacacc atgcaggcgc gctcgctcac tgtgtcgccg gtcatgctgc
    16261 gcaaggagtt gcgcgaacag caggaggggc aggtgagcgt cgacggcctg tcggatgacg
    16321 tcatccaggc ccaggtcgac gcgcgcgtgg aagacgttct gcgcacgatg gccaacgaga
    16381 tcccccgcat gattgagggg gcgcacgcca cagatccggc ggccgcgcag gcgcgagtga
    16441 gctcaaaaga catcctagac aagctgcacg cggattcaaa ctacgaggtt ctcgtgcgca
    16501 atgtcgaccc ggatgttgcc accaaggtgg ccaaaaagtt ccacggtgtc gcggcggatc
    16561 accaggatat tcgccaatac cccaatgggg cggtcgggga gaacatcgtc ggcaaggtct
    16621 ccatggacgg ccaggggcag ttcggcctcg aagcgtccag tgacagtgtc ctgaccggaa
    16681 ttaacggcag atccacggag gatgtctccg ctgacgggca gtcgattccg ggcacgctgc
    16741 gcgacgttgt cccggccgtc gacggatccc aggtcaagct caccatcgac gtcgatctgc
    16801 agacgttcgt gcagcgcacc ctcgagcaag cgaaggcgaa ctcgctggcg aaggacgccg
    16861 aggccgtcgt tctcgacgct cacacaggcg aggttctcgc gatggccaac accggcacga
    16921 ttgacccgaa tggtgatttg cagaaacagc tcgccgaggg gcgcagcttt gataacaact
    16981 ccatttcgca cccctacgag ccggggtctg tcgccaaggt gatcacggca gcggccgcca
    17041 tcgaggaggg gctgacaaac cccaccgagg tgcaccaggt tcccggctcc atcgacatgg
    17101 ccggcgtgac ggtcaaagac gcgtggtctc acggcgtggc cccctacacc acggcgggga
    17161 tcttcggtaa gtcctccaac gtgggcacgc tgcaaatcgc gcagcgcctc ggcgaggaca
    17221 agtactggga ctacctgcag cgcttcggta tcggacagtc gacgggaatc gagctcccca
    17281 acgaatctgc gggccttgta ccggtgctcg agcaatggtc gggcggcacc ttcgccaacc
    17341 tgcccattgg ccagggcatg agctggacga cgctgcagat ggccagcgtg taccaaaccc
    17401 tggccaacgg aggcgagaga atcgagccac gcattatctc ggaggtcatc ggccccgatg
    17461 ggcagtcgat ggaggctgac gccccggcgc gcacccgcgt ggtcagcgag gccaccgcga
    17521 agacgacggt ggacatgttc cgctccacgt tccagcagga ccctatgggt gtgaactccg
    17581 gtaccgccca gggcaacgag atcgagggct accagctggc gggaaagacc ggcacggccc
    17641 agaaagtcaa ccccgaaacc ggggcataca cgcagaacca gttctggatc accttcgccg
    17701 gtgtcgcgcc ggccgacgac cccaggtttg tcgtcgccgt catgctggat gaaccgcagc
    17761 gtggcccgct cgagggcgga tcgggcggcc agtcggccgc gccagtcttc cgtgagatcg
    17821 cgtcgtggct gctcaatcgc gaaaacatcc cgcagagccc gccctccgag ccgtacgtgc
    17881 tcgagcagcg ttaacccctt ttttcatgca agaggaatag aaaagacgta ggaccactac
    17941 cgagaggcga ggagaccagg tggaccaccg caacgagaac agtgccgcgg gcgcacccca
    18001 ggcgcccgtg ccgctgcacg agctcgcacg cattgccgga gccgatgtcg cgtcttcggc
    18061 tgataacggt tgggctggcg tagcgattag ctccgtgggg ctcaacgccc gcgaggtcgc
    18121 gccgggaggg ctgttcgccg ccctgccggg cacgcgtgtc cacggcgcgc agttcgccgc
    18181 ggagtctccc gcgcgcgcca tcctcaccga ccgcgagggc ctggacatcg tcgaagcggc
    18241 aggggatcgc cgccccgtgc tcgtcgtcga cgacgtccgc gccgtgctgg gcgaggtctc
    18301 ggcgcacgtc tacgggcacc cctcgcgccg catgacactt atcggggtca ccggcacgtc
    18361 gggcaagacg accaccacct acctgctgga gcgcgggctg atcgccgccg gcgcccaggt
    18421 cgggctaatc ggcacgacgg ggacgcgcat ccgcggccgc gacgtgccca cctccctgac
    18481 cacgccggag gcgcccaccc tgcaagcgct gtttgcgcgc atggcggccg agggcgtgac
    18541 gcacgtggtc atggaagtca gttcgcacgc gctgagcctg gggcgcgtgg acggcacctc
    18601 gttcgacgcg gccggtttta ccaacctcag ccaggatcac ctcgacttcc acccgacgat
    18661 ggatgactac ttccaggcga aggcagcgtt tttcgatccc tcatcgccgg tcgccgcgtc
    18721 ggcaagcgtc gtgtgcgtcg atgacgaatg gggcgagcgg atggccgagc tcgcgtcgca
    18781 cccgctgcgg gtgggaaccc acgggcagga agggctcgac tgcagcgcgc ggctgaccgc
    18841 ggttcgcgac aacggggctc aagacatcga gctgcgtatc gacggccaaa ctcacgagtt
    18901 tacgctgccc ctgcccgggg cattcaacgt ggccaatgcg gcgctggcga cggcgctggc
    18961 gcgcgtggtg ggcgcggaca tgccgcagtt tgtccgcggg ctcgaaaacg ccgccgtgcc
    19021 gggtcgcatg gagcgtatcg acgccggcca ggacttcgtg gcggtcgtcg actacgcgca
    19081 caaaccggcc gcgatcgccg ccgtgctgga aacgctgcgc gagcaggtcg acggcaggat
    19141 cggcatcgcg gtcggagccg gaggcgaccg cgacaccacg aaacgcgccg tgatgggcca
    19201 gcaggcggcc acgcgcgccg acctcgtgat cgtcaccgat gacaacccgc gcaccgagga
    19261 tccggccgcg atccgcgctg ctgttttgcg cggcgcgcgg gaggccggca gcggcgccga
    19321 gatcagggaa tgcggcccac gcgccgaggc aatcgaccag cttgtggcct gggcactgcc
    19381 cggcgacgcg atcgtggttg tgggcaaggg ccacgaggtg gggcaaattg tcggcgacac
    19441 gacacaccac ttcgacgatc gcgaggagat gcgcagggca ctggccgaca acggctacgg
    19501 tgaaaatgat gctcacggca cccaccagcc ggacggtctt cacgggccgc aagagcttgc
    19561 agacggtaag gacttcttcg cacatgatcc cacttgagtt agccgcgatc gccaggatca
    19621 cgggcggcag actgagcgac gatgcggacc cgcacgcggt agtcgacggg ttcgtggagt
    19681 tcgactcgcg caaaatcacc ccgggcggct tgttcgtcgc cctgccgggc aagcatgtcg
    19741 acggccacaa cttcgcgcgc gacgcaattg cgcagggcgc ggccggagtt ctcgcggcta
    19801 aggatgtcgg cgtggccgcg gtgatcatgc ccaaggccgc caagcgtgag ggagataact
    19861 ccgggctcgc cgcaaacgac cccgacggtt ccgcggccgg agtcgtctca ggcatgtcca
    19921 agctggccag ctacgtggcg tccacgctga ccgcagagca cggcctgtcc atcgtgggta
    19981 tcacgggttc cgccgggaag acctcgacga aagacctcgt tgcctctgtg ctctccgccg
    20041 ctggtcaaac cgtcgcgccc ccgggttcct tcaacaacga gctcggccat ccgtacacgg
    20101 tgttgcgctg caccgaatcg acgaagttcc tagtcgcgga aatgtccgcg cgcggcatcg
    20161 gccacattgc gcacttggcg acgatcgccc cgcccaagtt cggcgtggtg ctcaacatcg
    20221 gttccgcaca cctgggggag ttcggttcca aggaaaacat cgctgcggcg aaaggagagc
    20281 tcgtcgaggc gctgccttcg gccgcggagg gtggcgtggc catcctcaac gccgacgatc
    20341 ccctcgtcgc cggcatggcg ccgcgcacac gcgcgcgcgt ggtcaccttc tctgggcagc
    20401 acggcgccgc cgactattac gccacggaca tctcgcttga cgacgtcacg cgcgccagct
    20461 tcacgcttca ctcaccccac aacgagccgc agcgcgtcga gctcaacgtc ttcggcgccc
    20521 accaggtttc caacgccctc gccgccgcgg cggtcggcat cgaaagcggc atcgacgccg
    20581 ccaccgttgc acgcagcctc agcagcgcgc acggcgagtc cggcaaccgc atggatgtgc
    20641 aaacacgcgc cgacggggtc accgtcatca acgacgccta caacgccaac ccggactcga
    20701 tgcgggccgg catcgccgcg ttgggcttca cggccgccgc gcgccccggt gtgcgctcca
    20761 tcgcggtgct cggcgagatg ggggagctcg gcggcgactc ggtcagcgcg caccgcgaac
    20821 tcggcaacga actggcgcgc taccgcgtca cccacctcgt cgctgtcggg gacaacgatg
    20881 cgatggacgc cctgaaggac cgcgcgcggg atcggggcat ctacgtcgcc tccgcccggg
    20941 acgtcgagga ggccacatcg ctggtccagg cgatcctgtc ggtgccccca atgggggagg
    21001 agggttggta cgagcgcgat gcgcgcgatg tggtgctggt caaggcgtcg aatgcgctcg
    21061 ggctgtgggc ggtggcgaac gccctgttgc gagga
//
