LOCUS       NZ_GG657757            21086 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Streptomyces viridochromogenes DSM 40736 supercont1.1, whole genome
            shotgun sequence.
ACCESSION   NZ_GG657757
VERSION     NZ_GG657757.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces viridochromogenes DSM 40736
  ORGANISM  Streptomyces viridochromogenes DSM 40736
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8653262)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Annotation of Streptomyces viridochromogenes strain DSM 40736
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8653262)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q.,
            Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z.,
            Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A.,
            Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L.,
            Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S.,
            Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   3  (bases 1 to 8653262)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q.,
            Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z.,
            Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A.,
            Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L.,
            Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S.,
            Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Arachne v. April 2007
            Genome Coverage                   :: 8x
            Sequencing Technology             :: ABI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000158955.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 10:17:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,837
            CDSs (total)                      :: 7,762
            Genes (coding)                    :: 7,256
            CDSs (with protein)               :: 7,256
            Genes (RNA)                       :: 75
            rRNAs                             :: 6 (5S)
            complete rRNAs                    :: 6 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 506
            CDSs (without protein)            :: 506
            Pseudo Genes (ambiguous residues) :: 0 of 506
            Pseudo Genes (frameshifted)       :: 293 of 506
            Pseudo Genes (incomplete)         :: 267 of 506
            Pseudo Genes (internal stop)      :: 21 of 506
            Pseudo Genes (multiple problems)  :: 72 of 506
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:49:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5873531
            Orig. end                         :: 5894617
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG657757.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation was added to the scaffolds in August 2010.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(173..1489)
                     /gene="aroA"
                     /locus_tag="SSQG_RS25985"
                     /old_locus_tag="SSQG_05260"
     CDS             complement(173..1489)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="SSQG_RS25985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05260"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_003992841.1"
                     /transl_table=11
                     /translation="MAPNTADTALWPAPHASGAVDATVHVPGSKSVTNRALVLASLSSE
                     PGWLRRPLRSRDTLLMAGALRAMGIEIEEGVGPDGTGEAWRVLPTGLRGPATVDVGNAG
                     TVMRFLPPVAALADGPVRFDGDPRSYERPLTGVIDALRQLGARIDDDGRGALPLTVHGS
                     GALEGGQVAIDASSSSQFVSALLLSGPRFNQGVEVRHTGSTLPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLVIEPDLSNAQPFLAAALVTGGKVVIPDWPAHT
                     TQPGDRLREIFTEMGGSCELTEYGLVFTGSGSVHGIDVDLGEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYDDHRM
                     ATAGAILGLGVEGVQIENVATTAKTLPDFPDLWTGMLGA"
     misc_feature    complement(1492..1508)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            complement(1600..2322)
                     /locus_tag="SSQG_RS25990"
                     /old_locus_tag="SSQG_05261"
     CDS             complement(1600..2322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="SSQG_RS25990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05261"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_003992842.1"
                     /transl_table=11
                     /translation="MDSTATASLASLWDEVSGTQPDPDLWVVIATLAAALAVVVPHGLW
                     RISRNAITIAHEGGHGLVALLTGRTLTGIRLHSDTSGLTVSRGKPHGIGMILTAAAGYT
                     APPLLGLGGAALLGAGRITLLLWVATALLLAMLVMIRNAYGALTLIITGGLFVVVSWLA
                     GPQVQAAFAYVVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCSLIGGGRWLLGL"
     gene            2373..3188
                     /locus_tag="SSQG_RS25995"
                     /old_locus_tag="SSQG_05262"
     CDS             2373..3188
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="SSQG_RS25995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05262"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_003992843.1"
                     /transl_table=11
                     /translation="MCGRYSASRRPEDLAGIFEVEKWEPEETLEPDYNVAPTKEVYAVL
                     DRPLKDVADPRPVRQLRKLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYYEWVTGTQERELEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDRTLP
                     DDHPQAWWVTCSVITTEAEQSPLAVAPADGPRALADIHPRMPLMLTSDRWDAWLDPSRT
                     DAGDLLELLAPPPAGLMRAYPVTTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            3190..3837
                     /locus_tag="SSQG_RS26000"
                     /old_locus_tag="SSQG_05263"
     CDS             3190..3837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522885.1"
                     /locus_tag="SSQG_RS26000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05263"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_039933627.1"
                     /transl_table=11
                     /translation="MTHVTNATTETVETDAGPARITWHEAKKARLVLAVSHGAGGGIEA
                     RDLKALAAVLPAHGVTVARVEQPWRVAGKKLAPAPRTLDVGWRGIWPALAGPGQPVVSG
                     GRSAGARVACRTATELGAHAVLALSFPLHPPGKPEKSRAEELLGSGVPTLVVQGGNDPF
                     GKPEEFPEGPYRLVEVPHGDHGFAVPKRAEISQDEAVAVITDAVVEWTGALG"
     gene            4094..4780
                     /gene="sigR"
                     /locus_tag="SSQG_RS26005"
                     /old_locus_tag="SSQG_05264"
     CDS             4094..4780
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="SSQG_RS26005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05264"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_039933629.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPDGQGGTAAETAAQRSARFERDALEFL
                     DQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRK
                     KQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKEALQAIPEEFRIA
                     VYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGMVPAGAGESNE
                     AKGSGS"
     misc_feature    4116..4131
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            4777..5088
                     /gene="rsrA"
                     /locus_tag="SSQG_RS26010"
                     /old_locus_tag="SSQG_05265"
     CDS             4777..5088
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="SSQG_RS26010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05265"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_003992846.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDREMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPGDLRAKVMGRIDLIRSGQAVPDKDVTASPATPTES"
     gene            5240..6571
                     /locus_tag="SSQG_RS26015"
                     /old_locus_tag="SSQG_05266"
     CDS             5240..6571
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047597.1"
                     /locus_tag="SSQG_RS26015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05266"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_039933630.1"
                     /transl_table=11
                     /translation="MEAVPARTRVYVACVALAALLCLLPPPGIRTPWWAVALLAALYAG
                     CERVARSRFVGISHPAGTFYPVLLAGAFLLPAPAAALVAVPGALLSPAGQRPVALRRIW
                     RAAQLVLGVWTAARVHTALGGRNAVLEGDVPYALGPAGAAVLAFCLVLALLDGGILVVA
                     ERVPVRRAWRGLVERSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVSWWAFAQ
                     YHRERAAHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMADERVEVLRFAGI
                     LHDVGKLGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIGFLGEARAAVLHHHERL
                     DGSGYPYGLLGRQIPESARVVAVADAFDAMTSTRSYSRARPVAVALAELERCAGSQFDP
                     VMVAALVEAVGRVGWRPAVTADDARTPRVPPPGAPLPSRPGAHR"
     gene            6568..7815
                     /locus_tag="SSQG_RS26020"
                     /old_locus_tag="SSQG_05267"
     CDS             6568..7815
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047595.1"
                     /locus_tag="SSQG_RS26020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05267"
                     /product="HD domain-containing protein"
                     /protein_id="WP_003992848.1"
                     /transl_table=11
                     /translation="MSAYRPPPLFTLVHACAALLAAGSLAATNNNGLEERRVALAFGVL
                     VTVGELTRRNGAQVREPAPLGAAAALSYALLGEAGGRPTHHGVAQAVAVVLAASLLGSV
                     PHVARGQGPTLDHLARRMLTVGFVAVCFQPPYNRGMFDHWGGPAYALLLLALLSLTALC
                     DAVLAAALAHSRTGWPFGPVLRDELRAVLGIGSAVIATGAVMALAVAVVGLWALPVFSV
                     PLLLAQMSFRRYAAVRATYRQTIASLARATEVAGYTPCGHARRVAALSQAVGRDLGLTE
                     PELTVLEYAALMHDIGQLSLVDPVPAGATAVLPAAEQRRIALLGGAVVRQTGVDEAVAV
                     VVERQADPYAEQPLAARIVRAVNAYEEKSREGGPGGPLTALEELRLATAGEYAPEVVES
                     LARVLARSSLTLPVAG"
     gene            7933..8913
                     /locus_tag="SSQG_RS26025"
                     /old_locus_tag="SSQG_05268"
     CDS             7933..8913
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="SSQG_RS26025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05268"
                     /product="hypothetical protein"
                     /protein_id="WP_003992849.1"
                     /transl_table=11
                     /translation="MRIFGKGRNRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRAPGAAHDAGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTAAGHTYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGLAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9044..9694
                     /gene="def"
                     /locus_tag="SSQG_RS26030"
                     /old_locus_tag="SSQG_05269"
     CDS             9044..9694
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="SSQG_RS26030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05269"
                     /product="peptide deformylase"
                     /protein_id="WP_003992850.1"
                     /transl_table=11
                     /translation="MAQQDTDQQRAGVLPVDDEGYVVDTEDCEEREAAWRERGTSRPIT
                     VVGNPVLHKECKDVTDFGDEFQQLVADMFASQRTAEGVGLAANQIGVDAKVFVYDCPDD
                     EGVRHTGVVCNPKLVELPAEKRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            10001..11086
                     /gene="cyc1"
                     /locus_tag="SSQG_RS26035"
                     /old_locus_tag="SSQG_05270"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="SSQG_RS26035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05270"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_003992851.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-64, bitscore: 217.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALSHGTTSTPTTIAVPPSLSLPVIEATFTRQLHAYWPKCQEKT
                     RAWLLEKRLMPADKVEEYADGLCYTDLMAGYYVGAPDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPVAWRRLRDRLHSALDAPAEHLHHEDPLVAGFADSVSRLYAFLPRTWNLRFAR
                     HFHAVIDAYDREFHNRTRGIVPTVEEYLRLRRLTFAHWIWTDLLEPAAGCELPDAVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHEGLTLEQAIVEVRRRVE
                     TCITEFLDIEEEAIRFADDLADGTVRGKELSAAVRACVSNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     gene            11083..12453
                     /locus_tag="SSQG_RS26040"
                     /old_locus_tag="SSQG_05271"
     CDS             11083..12453
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="SSQG_RS26040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05271"
                     /product="cytochrome P450"
                     /protein_id="WP_003992852.1"
                     /sec_met_domain="p450 (E-value: 1.3e-71, bitscore: 240.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESAQPEAPPAPDLREPPRAGGGVPFLGHGWKLVRDPLEFMSR
                     LRDHGDVVRLKLGPKTVYAVTTPELTGALALSNDFIIAGPLWESLEGLLGKEGVATANG
                     PVHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWKPGETIDCTSESFRVAVRVAAR
                     CLLRGDYMDERAERLCVALATVFRGMYRRMVVPLGPLYMLPLPANREFNRALADLHLLI
                     DEIVAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETVASTIMWL
                     LHMLAEHPEHADKVREEVEAVTGGRPVAFQDVRNLRHTNNVVVEAMRLRPAVWILTRRA
                     VRDTELGGYRIPAGADIVYSPYAIQRDAKSYERNLEFDPDRWLPDRVKDIPKHAMSPFS
                     TGNRKCPSDHFSMAQLTLITAALATSYRFEQVAGSNAATRVGITLRPHDLRLRPVRR"
     gene            complement(12467..13429)
                     /locus_tag="SSQG_RS26045"
                     /old_locus_tag="SSQG_05272"
     CDS             complement(12467..13429)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700022.1"
                     /locus_tag="SSQG_RS26045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05272"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_039933633.1"
                     /transl_table=11
                     /translation="MLQNVAVALLDGVNPFELGVVCEVFGTDRSDDGLPVYDFAVASAE
                     GPVLRMNSGFSLQVGHGLERLEAADLIAVPAGHSYASRDFPPDLLDALRHAVDRGARVL
                     SVCSGVFVLAAAGLLDGRRCATHWKHAKDLARQYPRVVVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGSEVANKIARRMVVPPHRDGGQAQYIERPLPHPEGDTIGEVLAWME
                     RHLDEEVTVEQLAVHAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETMD
                     AIAGRTGFGNAATLRHHFVRAVGTTPNTYRRTFRGPEAA"
     gene            13523..13765
                     /locus_tag="SSQG_RS41940"
                     /old_locus_tag="SSQG_05273"
     CDS             13523..13765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="SSQG_RS41940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05273"
                     /product="hypothetical protein"
                     /protein_id="WP_167545767.1"
                     /transl_table=11
                     /translation="MNTNQIEALIGLTATFGILVLLILPSVFGLVRERRIDRQIREAQE
                     ARESEPAQKSSSRSTVPSTATWYAEGRRSKKLVNS"
     gene            complement(13678..14685)
                     /locus_tag="SSQG_RS26055"
                     /old_locus_tag="SSQG_05274"
     CDS             complement(13678..14685)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190555.1"
                     /locus_tag="SSQG_RS26055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05274"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_039933635.1"
                     /transl_table=11
                     /translation="MSTQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSD
                     VADLAKLSPAEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAV
                     HVQFYLTLLDTYLPDPEDRTAAFAAVENIPSIREKASFCFKWMDSVEKLDRLETQADRR
                     RFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFDVV
                     DTVRKEEPELFDDQLRQEVTDMLREAVEAELQFARDLCGDGLPGMNTESMRQYLECVAD
                     QRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(14685..17042)
                     /locus_tag="SSQG_RS26060"
                     /old_locus_tag="SSQG_05275"
     CDS             complement(14685..17042)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="SSQG_RS26060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05275"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_039933636.1"
                     /transl_table=11
                     /translation="MTIAPADPVSAAAEQHDGPGAALLRTLTELTADLPDTDPGRVAAA
                     ALRGRSARADEAELRDLATEAAAGLISEDPAYSRLAARLLTIGIRAEAASQGVTSFTES
                     VVVGHREGLIADRTAEFVRLHAARLDALIDPAADDRFGYFGLRTLHSRYLLRHPLTRKV
                     VETPQHFMLRVAAGLAEDHTARSVDEVAALYELMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPKDELDSIYDRYHQVARLSKHAGGIGLAYSRIRARGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDVEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADAQWSLFSPSDVPELVDLWGEEFDTAYRAAEAKGLAKRTLPARELYGRMMRT
                     LAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTSDGETAVCNLGSVNLGA
                     FVDTSTGDLDWDRLDATVRTAVTFLDRVVDINFYPTEQAGRSNSRWRPVGLGAMGLQDV
                     FFKLRLPFDSPEAKALSTRIAERIMLAAYEASADLAERSGPLPAWEKTRTARGVLHPDH
                     YDVELTWPERWAALRERIAATGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVDELKRLGVWDARSREALREASGSVQDFAWIPEDVRALYRTAWEIPQ
                     RGLIDMAAARTPFLDQSQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIA
                     RAAQATVPAQATPDPEAVACSLENPESCEACQ"
     regulatory      complement(17188..17270)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17285..17298)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17292..17306)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17323..17337)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            complement(17348..17854)
                     /locus_tag="SSQG_RS26065"
                     /old_locus_tag="SSQG_05276"
     CDS             complement(17348..17854)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="SSQG_RS26065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05276"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_003992857.1"
                     /transl_table=11
                     /translation="MDILIRRVKPAEHDALGEITAQAYLKDGLLDFGESDWYLGELRDV
                     AKRAAAADVLVATQGEHLLGGVTFVPSGGPMTDIARPGEAEIRMLAVAHEARGRGAGEA
                     LVRACVDRARATDGCVRVVLSTQRTMHSAHRIYERLGFVRVPERDWNPIPELPDITLLT
                     YELTL"
     gene            complement(17926..19551)
                     /locus_tag="SSQG_RS26070"
                     /old_locus_tag="SSQG_05277"
     CDS             complement(17926..19551)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="SSQG_RS26070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05277"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_003992858.1"
                     /transl_table=11
                     /translation="MKDGVNGVALAVFIFFFLAVTAMGFLAARWRKAENDSLDEWGLGG
                     RSFGTWITWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLWS
                     VSHKHGYVTTSDFVRGRFGSKGLSLAVALTGILATMPYIALQLVGIQAVLDVMGVGGGE
                     NTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGGF
                     DDIFAKAGDAFSQTNPATGAPRGALAPPETGQWTYATLALGSALALFMYPHSITATLSS
                     KSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGIKVQNGQLAIPQLFETMFPDWFAGV
                     AFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGALV
                     FVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTVAAYG
                     VASPTQKHFGGSAKEIPGIGEIGYIGLTAFVLNVVVTVVLTFVLKAVKAPDGIDETRPE
                     DYTADAGDPGVQVELPPATAGTSH"
     gene            complement(19548..19814)
                     /locus_tag="SSQG_RS26075"
                     /old_locus_tag="SSQG_05278"
     CDS             complement(19548..19814)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925869.1"
                     /locus_tag="SSQG_RS26075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05278"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_003992859.1"
                     /transl_table=11
                     /translation="MSQAPEASRGPVVTPMRVVIAVCLIAPFVAMLWVGSYAKTDPAFI
                     GIPFFYWYQMAWVLISTALTMIAYKLWQRDQRARSAAKGGASE"
     misc_feature    complement(19885..19899)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            complement(19964..20728)
                     /locus_tag="SSQG_RS26080"
                     /old_locus_tag="SSQG_05279"
     CDS             complement(19964..20728)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="SSQG_RS26080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSQG_05279"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003992860.1"
                     /transl_table=11
                     /translation="MSTDVSSAENENGAPVRTARVPKYYRLKKHLLDMTDTQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDVGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDREGQPVEWVRSVYRGDRYKFVARLKRPAE"
     misc_feature    20759..20774
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    20764..20782
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.03"
                     /tool="antismash"
     misc_feature    20788..20803
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.46"
                     /tool="antismash"
     misc_feature    complement(20956..20971)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.29"
                     /tool="antismash"
ORIGIN
        1 accaggcagg tcagacggcc ccggtcgact gtgagcacga gcccctcggc ggcgtcctcg
       61 tgcttggggc ggatgttcgt ccggggccgg gtgttccggc ggcccgggcg ggtgcggatg
      121 tcgtcctcgt cggtgtgctt gccgtagcgc cgcatgacgt gatccctgcg ccctacgccc
      181 cgagcatccc ggtccacagg tcggggaagt cgggcagggt cttcgccgtc gtcgccacgt
      241 tctcgatctg cactccctcc accccgaggc cgaggatcgc gccggccgtg gccatgcggt
      301 ggtcgtcgta cgtgtggaag accccgccgt gcaggcggcg cgggcggatg tgcagcccgt
      361 cggcggtctc ggtgacgtca ccgccgagtt cgttgatctc cttcgtcagc gcggccagcc
      421 ggtccgtctc gtgcagccgc aggtgggcca cgccgcgcag ggtcgacggc gagtccgcga
      481 gggccgcgac cgcggcgatg cccggcgtca gctcgccgac ctcgcccagg tcgacgtcga
      541 tgccgtggac cgagcccgag ccggtgaaca cgagcccgta ctcggtcagt tcgcaggagc
      601 cgcccatctc ggtgaagatc tcgcgcagcc ggtcaccggg ctgggtggtg tgggccggcc
      661 agtcggggat gacgaccttg ccgccggtca ccagggccgc cgcgaggaac ggctgggcgt
      721 tggacaggtc cggctcgatg acgaggtccc ggccgagcag ggcgcccggc gtgacccgcc
      781 agacgttcgg ctcgccgccc gactcgggcg tgtccacctg cgcgccgacc gcgcgcagca
      841 tgtcgacggt catccggatg tgcggcatgg agggcagcgt gctgccggtg tggcggacct
      901 cgacgccctg gttgaagcgg gggccggaca gcagcagggc gctcacgaac tgcgacgagg
      961 aggacgcgtc gatcgcgacc tggccgccct ccagggcgcc gctgccgtgc acggtcaggg
     1021 gcagtgcgcc acggccgtcg tcgtcgatcc gggcgccgag ctgacgcagc gcgtcgatga
     1081 caccggtcag gggacgctcg taggagcggg ggtcgccgtc gaaccggacg ggaccgtcgg
     1141 cgagcgcggc gaccggcggc aggaaccgca tcaccgtgcc ggcgttgccg acgtcgaccg
     1201 tggccgggcc gcgcaggccc gtggggagca cccgccaggc ctcgccggtg ccgtcggggc
     1261 ccacgccctc ctcgatctcg atgcccatgg cacgcagcgc gccggccatc agcagggtgt
     1321 cgcgggagcg gagcgggcgg cggagccagc cgggctcgga ggacagggag gcgaggacca
     1381 aggcgcggtt ggtgaccgac ttggaccccg gcacgtggac cgtcgcgtcg acggctccgc
     1441 tcgcgtgcgg ggcgggccag agggcggtgt ctgcggtgtt cggggccatg gcccccactt
     1501 tataagcagg cagtggttcg agtgctgctg cgtcgtggct ggtcgcgccc cacggcggag
     1561 ccgcagatcg gcacagcccc gcgccctgag gtgggctggt cacaagccca gtagccagcg
     1621 ccctcccccg atcagcgagc acaacgacac cgcgtggaac aggaagagcc acaagcccgc
     1681 cggcacatgt gtcagccgcg acagctggtc ggcgtccgag tcacccgcac cgccccgcga
     1741 ccgcttcgcc tggagctcga acgccggccg caccccgccc agcaacagga accacaccac
     1801 cacgtaggcg aaggccgcct gtacctgcgg accggccagc caggagacca cgacgaacag
     1861 cccgccggtg atgatcaggg tcagggcgcc gtaggcgttg cggatcatca cgagcatggc
     1921 caggagcagg gccgtggcca cccacagcag gagcgtgatg cggccggcgc cgagcagggc
     1981 cgcgccgccg aggcccagca ggggaggggc ggtgtagccg gcggccgcgg tgaggatcat
     2041 gccgatgccg tgcggcttgc cgcggctgac ggtcaggccg ctggtgtccg agtgcagacg
     2101 tatgccggtg agggtgcggc cggtgagcag ggccacgagc ccgtggccgc cctcgtgggc
     2161 gatggtgatg gcgttgcggg agatgcgcca cagaccgtgc gggaccacca cggccagcgc
     2221 ggcggccagg gtcgcgatca ccacccagag gtcggggtcg ggctgcgtac cggagacctc
     2281 gtcccagagg gaggcgagcg aggcggttgc ggtgctgtcc atgtaaggcg ttggctccct
     2341 gtgggcggat ggaatctggc agtgtggcac gtatgtgcgg acggtattca gcgagtcgta
     2401 ggccagagga tctcgcagga atctttgagg tcgagaagtg ggagcccgag gagactctgg
     2461 agccggacta caacgtcgcg cccaccaaag aggtctacgc cgtcctcgac cgccctttga
     2521 aagacgtggc cgacccgcgc ccggttcgcc agctgcgcaa gctgaagtgg ggcctcgtcc
     2581 cgtcctggtc gaagaccccc gagggcggtg cccggatgat caacgcacgg gcggagaccg
     2641 tccacgagaa gccgtcctac cgtcgcgcct tcacctcccg gcgctgcatc ctgcccgccg
     2701 acggctacta cgagtgggtc accggcacgc aggagcgcga gctggaggtc gagggcaaga
     2761 agaagcgccc gcgcaagcag ccctacttcg tgacgcccgc ggacgggtcg gtcttcgcga
     2821 tggccgggct gtacgagttc tggcgggacc gcacgctgcc ggacgaccac ccgcaggcct
     2881 ggtgggtgac gtgctcggtc atcacgacgg aggcggagca gagccccctc gcggtggccc
     2941 cggccgacgg gccccgggcc ctggccgaca tccatccccg gatgccgctg atgctgacgt
     3001 ccgaccgctg ggacgcctgg ctggacccgt cccgcacgga cgccggcgac ctgctcgaac
     3061 tgctcgcccc gccgcccgcc gggctgatgc gcgcctaccc cgtcaccacg gccgtcagca
     3121 acgtccgcaa caacgggccg gagctgctga aggagctgga agggcccgaa gagggcacac
     3181 tcttctgacg tgacgcatgt gacgaacgcg acgacggaaa ccgtcgagac cgacgccggc
     3241 cccgcccgca tcacctggca cgaggcgaag aaggcgcggc tggttctcgc cgtcagccac
     3301 ggcgccggcg gcggcatcga ggcccgtgac ctgaaggccc tggccgccgt cctgcccgcg
     3361 cacggcgtga ccgtggcccg cgtggagcag ccctggcggg tggccgggaa gaaactggca
     3421 cccgcgccca ggaccctgga cgtcggctgg cgcggcatct ggcccgcgct ggccgggccc
     3481 ggccagcccg tggtgtccgg cgggcgcagc gccggggccc gggtcgcctg ccgcaccgcc
     3541 accgagctcg gcgcccacgc cgtcctcgcc ctcagcttcc cgctgcaccc gccgggcaag
     3601 cccgagaagt cccgagcgga ggaactgctg ggttcagggg tgcccacgct ggtcgtccag
     3661 ggcggcaacg acccgttcgg gaagccggag gagttccccg aggggcccta ccggctcgtg
     3721 gaggttccgc acggggatca cggcttcgcc gtgccgaagc gtgcggagat ctcgcaggac
     3781 gaggccgtgg cggtcatcac ggacgcggtc gtcgagtgga ccggggcgct cgggtaaagc
     3841 ttcgggaatg ccggggcggc ggtcactgtt gtgcgggacg tacgtgctgg agaccagcac
     3901 cgacgccgta ggagagggag tccgccgcat gggttcgacc atctgcccga cccgcagcag
     3961 ccgcgccgac ctggactgga cggtgctgca cgcggccagg accgccccga ttcgggcggc
     4021 gggcgggccg gatcgtcgtc tatcctccga ttcgggtgag accgctttcg gtctcacgag
     4081 aacacttgag gaggtgggtc cggtcacagg gaccgacgca gggaccgaac acggccaggc
     4141 ggagcagccc gacggccagg gcggcacggc cgccgagacg gccgcgcagc gcagtgcgcg
     4201 cttcgaacgg gacgcgctcg agttcctcga ccagatgtac tcggccgcgc tgcgcatgac
     4261 gcgcaacccg gccgacgccg aagacctggt gcaggagacg tacgccaagg cgtacgcgtc
     4321 cttccaccag ttccgcgagg gcaccaacct caaggcgtgg ctgtaccgga tcctcaccaa
     4381 caccttcatc aactcgtacc gcaagaagca gcgcgaacct cagcgcagcg cggccgagga
     4441 gatcgaggac tggcagctcg cccgcgccga gtcgcacatg tcgacgggtc tgcgctccgc
     4501 ggagtcgcag gcgctcgacc acctgcccga ctcggacgtg aaggaagcgc tccaggcgat
     4561 ccccgaggag ttccgcatcg ccgtgtatct ggcggacgtc gaggggtttg cctacaagga
     4621 gatcgccgac atcatgggga cacccatcgg tacggtgatg tcccggctgc accggggccg
     4681 ccgtcagctg cgcggcatgc tggaggacta cgcccgcgac cgtgggatgg tcccggccgg
     4741 cgccggagag tcgaacgaag cgaaaggctc ggggtcatga gctgcggaga gccgcacgag
     4801 acggattgca gcgaaatcct cgatcatctc tacgagttcc tcgaccgtga gatgccggac
     4861 tcggactgcg tgaagttcga gcaccacttc gaggaatgct cgccctgcct cgagaagtac
     4921 gggctcgagc aggccgtgaa aaagctggtc aagcgttgct gcgggcatga cgacgtgccg
     4981 ggcgacctgc gcgccaaggt catggggcgg atcgacctga tccgctccgg ccaggcggtc
     5041 cccgacaagg acgtcaccgc ctcgcccgcc acgccgacgg agtcctgaga ctcctgcgcc
     5101 tttcaactac ccccctcccg agggggtagt catcctcgaa ggcgtcactc gaacgtgcta
     5161 acccgcgggc tatcggcccg cggagccccc tctggcgtcc taggctccgg gcctgacggt
     5221 catggccggg gaggggctca tggaagcggt accggcgcgg acacgtgtgt atgtcgcctg
     5281 tgtcgccctg gccgccctgc tctgcctgct gccgccgccg ggcatccgca cgccctggtg
     5341 ggccgtcgcg ctgctcgccg cgctgtacgc gggctgcgag cgtgtcgccc ggtcccggtt
     5401 cgtcgggatc tcccaccccg ccgggacctt ctaccccgtg ctgctcgcgg gtgccttcct
     5461 gctgcccgcg cccgccgccg ccctggtggc ggtgcccggt gcgctgctgt ctcccgccgg
     5521 gcagcggccg gtggcgctgc gccggatctg gcgggcggcc cagctcgtcc tcggcgtgtg
     5581 gaccgcggcc cgggtgcaca cggcgctcgg cggacggaac gccgtgctcg aaggcgacgt
     5641 cccctacgcc ctcggaccgg ccggggcggc cgtgctggcg ttctgcctgg tgctcgcgct
     5701 gctggacggc ggaatcctgg tcgtggcgga gcgggtgccg gtgcggcggg cctggcgggg
     5761 gctggtggag cgctccctgg cgccgatcgc cgtgcacggg ctggccgggc tgatgatggc
     5821 cgtgctgtgg cgcagcccgt acggacccgt ggccgcgctg ctcgtgctgc tgccgatgtg
     5881 cgtctcctgg tgggccttcg cgcagtacca ccgggaacgg gccgcccacc aggcgaccat
     5941 ccgggcactg gtccaggccg tcgacatcaa ggacggctac acgcgcgggc acagcgagcg
     6001 cgtcgggcag gcctccatga tgatcgcgcg tgagctgggc atggccgacg agcgcgtcga
     6061 ggtgctccgc ttcgccggga tcctgcacga cgtcggcaag ctcggcgtgc ccacccggct
     6121 gctcaggaag gacgggccgc tgacgcccga ggagcggcgg gtgatcgagc tgcaccccga
     6181 gtacgggcac gagatggtgc ggggcatcgg cttcctcggc gaggcccgcg cagccgtact
     6241 gcaccaccac gaacggctgg acggcagcgg gtacccgtac gggctgctgg gccgtcagat
     6301 cccggaatcc gcccgggtgg tggcggtcgc ggacgccttc gacgcgatga cctccacccg
     6361 gagctacagc cgggcccggc ccgtcgcggt ggccctggcg gagctggagc ggtgcgccgg
     6421 cagccagttc gacccggtga tggtcgcggc tctcgtggag gccgtcggcc gggtgggatg
     6481 gcgccccgcc gtgaccgccg acgacgcccg cacgccccgc gttcccccgc ccggcgcgcc
     6541 cctccccagc aggccgggag cacaccgatg agcgcctacc ggccgccccc gctgttcacc
     6601 ctcgtccacg cctgtgccgc cctcctcgcc gccggatccc tcgccgcaac aaacaacaac
     6661 gggctggagg aacgccgggt cgctctcgcc ttcggcgtcc tcgtcaccgt gggggagctc
     6721 acacggcgca acggggcgca ggtcagggaa cccgcgccgc tcggcgccgc cgcggccctg
     6781 tcgtacgcgc tgctcggcga ggccggcggc cggcccacgc accacggtgt cgcccaggcc
     6841 gtcgccgtcg tcctggccgc ctcgctgctc ggcagcgtgc cgcacgtcgc ccggggacag
     6901 gggcccacgc tcgaccacct ggcccgccgg atgctcaccg tcgggttcgt cgccgtgtgc
     6961 ttccagcccc cgtacaaccg gggcatgttc gaccactggg gcggccccgc ctacgcgctg
     7021 ctgctgctcg cgctgctctc cctgaccgcg ctgtgcgacg cggtgctcgc cgccgcgctg
     7081 gcccactccc gcaccggctg gcccttcggg cccgtgctgc gggacgagct gcgcgccgtg
     7141 ctcggcatcg ggtcggccgt catcgccacg ggtgcggtga tggcgctggc ggtcgccgtc
     7201 gtcggcctgt gggcgctgcc cgtcttctcc gtgcccctgc tgctcgccca gatgtccttc
     7261 cggcgctacg cagccgtccg ggcgacctac cggcagacca tcgcctccct cgcgcgggcc
     7321 accgaggtcg ccgggtacac cccctgcggg cacgcccggc gggtggccgc gctcagccag
     7381 gcggtggggc gtgacctggg cctcaccgag cccgagctga cagtgctgga gtacgccgcg
     7441 ctcatgcacg acatcggcca gctgagcctc gtcgacccgg tcccggcggg cgccaccgcc
     7501 gttctgcccg ccgcggaaca gcggcgtatc gcactgctcg gcggggccgt cgtccggcag
     7561 acgggcgtcg acgaagcggt ggccgtggtc gtggagcggc aggccgaccc ctacgccgaa
     7621 cagccgctcg ccgcgcggat cgtccgtgcg gtgaatgcgt acgaggagaa gtcccgggaa
     7681 ggtggtcccg gcgggccgct gacggcgctg gaggaactcc ggctcgccac cgccggggag
     7741 tacgccccgg aggtggtgga atcactggcc cgggtactgg caaggagcag tctgaccctg
     7801 cccgtggctg ggtaacccat gggtaatgag cgccctcgag gccgcacgtg gttggatgcg
     7861 aaggagaagg tgtccggggg ctcgcaacac agctatggcc agcccaccgc acggaactgg
     7921 caggcgggaa tcgtgaggat cttcggcaag ggacggaacc ggccctccgc ctcctggcgg
     7981 caggccacag accgggcgtt cacactcatc ggcgacggcc ggtacgagga cgccggcgcg
     8041 ctgttgacac gtgccgccga cctggagccg tggctctccg agtcctggtt caacctcgct
     8101 ctgctgcaca agttccggca cgactgggaa caggcgcggg cggcgggcct gagggccgtg
     8161 gccctgctcg accgggacac cggcgcgccc gactggtgga acgtcggcat cgccgcgacc
     8221 gccctccagg actggccgct ggcccggcgc gcctggcagg cctacgggct gcgggcgccg
     8281 ggggccgccc acgacgccgg tgagcccgtc ggcatggacc tcggcagcgc ggccgtccgg
     8341 ctgtccccgg aaggggaggc cgaggtcgtg tgggggcggc ggctggatcc cgcgcggatc
     8401 gaggtgctgt ccattccgct gccgtcgtcg gggcggcgct ggggcgaggt cgtcctgcac
     8461 gacggcgtgc cgcacgggga gcggaccacg gccgccgggc acacgtaccc ggtgttcgac
     8521 gagatcgagc tgtgggcgcc gtccccggtg ccgacctggg tggtgctgct ggaggcggcg
     8581 accgagtcgg accgggacgc gctggagcag ctcgcggcgg acgccgggtt cgccgcggag
     8641 gactggtcct cttcggtgcg gttgctgtgc cggatgtgct cggagtcacg gatgccctcc
     8701 gacgagggcg acggggagca tctcgacccg catgatcaca gtgagccggg gcatcccggg
     8761 ccgctggggc accggacgga cgggcagctg tgggtgccgg agcgggagtg cgggttggct
     8821 gcgccggctt cgctggtcag ggggcttttg gacgggtggg tggccgacag tccggattct
     8881 cgtgactggc gggatctgga agaggtgtgc taggtcgtcc gacgggtgcg gcgctgtggt
     8941 gggggttgat cgcgcagttc cccgcgcccc tgagggggcg ccttccccgt accctgtatc
     9001 agcatcccag cttggatttg ttcaggaagg cgtacgtaac gtcatggctc agcaggacac
     9061 cgatcagcag cgtgcgggcg tgcttcccgt cgacgacgag gggtacgtgg tcgacacgga
     9121 ggactgcgag gagcgcgagg cggcctggcg ggagcggggg acctcgcggc cgatcacggt
     9181 ggtcgggaac ccggtgctgc acaaggagtg caaggacgtc accgacttcg gcgacgagtt
     9241 ccagcagctc gtcgcggaca tgttcgccag ccagcgcacc gccgagggcg tcggtctcgc
     9301 cgccaaccag atcggcgtcg acgcgaaggt cttcgtctac gactgccccg acgacgaggg
     9361 cgtccggcac accggtgtcg tctgcaaccc caagctcgtg gaactgcccg ccgagaagcg
     9421 ccggctggac gacagcaacg agggctgcct gtcggtgccc accgcgtacg cgccgctcgc
     9481 ccggcccgac tacgccgagg tgaccgggca ggacgagaag ggcaacccga tcaaggtgcg
     9541 cggcaccgga tacttcgctc ggtgtttgca gcacgagacg gatcacctgt acggctacct
     9601 gtacatcgac cggctctcca agcgggaacg caaggacgcg ctgcggcaga tggccgagaa
     9661 cgagccccgc taccccgtgg tggccaacga ctgaggcgtc ggcctcacct cagcctcacc
     9721 aggagaacgg cgtctgttcg ggtttctcat cccgaacagg cgccgttcgt ctgtgccgtt
     9781 cgtctgtgcg tcgcacgttc gatcgcatct gctcttcttg tgatccggtg cccgtcacac
     9841 accgggagga tcccggcact gtggggtagt gaatgaagca aatgcgttcc cagaagagtc
     9901 agttgtggtg ctgaatgggg tgagcggggt atgcaacggc gcacgcccgg cacgaaggga
     9961 ggggcgctcg cgccaactgg cggctgagag gggttagttc gtgcatgctt tgtcacacgg
    10021 caccacatcg acaccgacca cgatcgcagt tccaccgtcg ctctctctcc cggtgatcga
    10081 ggcgacgttt acccggcaac tccacgcgta ttggccgaag tgccaggaga agacccgcgc
    10141 ctggctgctc gaaaagcggc tcatgcccgc ggacaaggtt gaggaatatg ccgacggcct
    10201 gtgctacacg gacctcatgg cggggtacta cgtcggcgcc cccgacgagg tcatgcaggc
    10261 gatagcggac tacagcgcct ggttcttcgt ctgggacgac cggcacgatc gcgacatcgt
    10321 gcacggtcgt ccggtcgcct ggcggcgcct gcgggaccgc ctgcactcgg cgctcgacgc
    10381 accggcggag cacctgcacc acgaggaccc actggtcgcc gggttcgcgg acagcgtgtc
    10441 gcggctgtac gcgtttctgc cgcggacgtg gaacctccgg ttcgcccggc acttccacgc
    10501 ggtgatcgac gcctacgacc gggagttcca caaccgcacc cgcggaatcg tgcccacggt
    10561 cgaggaatat ctccgtctgc gccggctcac cttcgcccac tggatctgga cggacctgct
    10621 ggagccagcc gcgggctgcg aactcccgga cgccgtccgg aaacacccgg catatcgacg
    10681 ggcggcactg ctgagccagg agttcgccgc ctggtacaac gacctctgct cactgccgaa
    10741 ggaaatagcg ggcgacgagg tgcacaatct cggaatcagt ctcatcaccc atgaggggct
    10801 gacgctggaa caggcgatcg tggaagtccg gcgccgtgtc gagacctgca taacggaatt
    10861 cctcgacatc gaagaggaag caatacggtt cgccgacgac ctcgccgacg gtaccgtgcg
    10921 gggaaaggaa ctgagcgccg ccgtgcgggc ctgtgtgagc aatatgcgga actggttcag
    10981 ttccgtctac tggttccatc acgagtccgg ccggtacatg gtcgacagct gggacgaccg
    11041 gtccacgccc ccgtacgtca acaacgaagc ggcaggtgag aaatgaccgt cgagtctgca
    11101 cagcccgaag cccctcccgc tcccgacctg cgtgagccgc cccgggcagg cggcggtgtg
    11161 cctttcctcg ggcacggctg gaagctggtg cgcgatccgc tggagttcat gtcccggctc
    11221 cgggaccacg gtgacgtggt ccggctgaaa ctcgggccga agacggtgta cgcggtgacc
    11281 accccggagc tcaccggcgc gctcgcgctg agcaacgact tcatcatcgc cgggccgctg
    11341 tgggagtccc tggagggcct gctcggcaag gagggcgtgg ccacggcgaa cggcccggtg
    11401 caccggcgcc agcggcgcac catccagccc gccttccggc tcgacgccat ccccgcctac
    11461 gggccgatca tggaggagga ggcgcatgcg ctgaccgagc gctggaagcc gggggagacc
    11521 atcgactgca cctccgagtc ctttcgggtg gccgtgcgcg tcgcggcccg ctgcctgctg
    11581 cgcggcgact atatggacga gcgggcggag cggctgtgcg tcgcgctcgc caccgtcttc
    11641 cgcgggatgt accggcggat ggtggtgccg ctcggaccgc tctacatgct gccgcttcct
    11701 gccaaccgcg aattcaaccg ggcattggcc gatttgcatc tcctgatcga cgagatcgtc
    11761 gccgagcgcc gagcatccgg tcaaaagccg gacgatttgc tgacggcatt gctggaggcg
    11821 aaggacgaca atggcgaccc catcggggaa caggagatcc acgaccaggt cgtcgcgatc
    11881 ctcactcccg gcagcgaaac cgtcgcgtcc acgatcatgt ggctcctgca catgctcgcg
    11941 gaacatccgg aacacgcgga caaggtgcgc gaggaagtag aagccgtcac cggtgggagg
    12001 ccggtggcat tccaggacgt ccggaacctc aggcacacca acaatgtcgt cgtggaggcg
    12061 atgcgtttgc gtcccgccgt ctggattctg acgcggcggg cggtgcggga cacggaactc
    12121 ggtggatatc gcattccggc cggtgcggac atcgtctaca gcccgtacgc gatccagcgc
    12181 gatgcgaagt cgtacgagcg gaacctggag ttcgaccccg accgctggct cccggaccgg
    12241 gtcaaggaca tcccgaagca cgccatgagc ccgttcagca ccggcaaccg caagtgcccg
    12301 agcgaccact tctccatggc gcagctgacg ctgatcacgg cggccctggc caccagctac
    12361 cgcttcgaac aggtggccgg ttcgaatgcc gcaacgcggg tcggcatcac gctccggccg
    12421 cacgacctgc ggctgcggcc ggtgcggagg tgacagccgt gtcgcctcag gccgcttcgg
    12481 ggcctctgaa cgtcctccgg taggtgttcg gtgtcgtccc caccgcccgg acgaagtggt
    12541 ggcgcagcgt cgccgcgttg ccgaaccccg ttcggccggc gatcgcgtcc atcgtctcgt
    12601 ccgtcgcttc cagcaaccgc tgggccagca gaacgcgctg gcgcaggatc cagcggtagg
    12661 gagtcgtccc cgtctcctgc tggaagcggc gggcgaaggt gcgcggggac atgtgggcgt
    12721 ggacggcgag ctgctcgacg gtgacctcct cgtcgagatg acgctccatc cacgccagga
    12781 cctcgccgat cgtgtcgccc tcggggtggg ggagcgggcg ctcgatgtac tgcgcctggc
    12841 cgccgtcgcg gtgcggtggc accaccatcc gccgggcgat cttgttggcg acctcggagc
    12901 cctgttcctt gcgcaccagg tggaggcagg cgtcgatgcc ggcggccgtg ccggcggagg
    12961 tgatcaccgg gtcctcgtcg acgtagagca cgtccggttc gacgaccacc cgtgggtact
    13021 gccgggcgag gtccttcgcg tgcttccagt gcgtggcaca gcggcggccg tccagcagcc
    13081 cggccgcggc cagcacgaag accccggagc agacgctcag cacccgggcg ccgcggtcga
    13141 ccgcgtgacg cagggcgtcc agcagatccg gcgggaagtc ccggctcgcg tagctgtgcc
    13201 cggccggcac ggcgatcaga tcggccgcct ccagccgctc caggccgtgc ccgacctgga
    13261 gcgagaagcc cgagttcatg cgcagcaccg gcccctcggc cgaggcgacg gcgaagtcgt
    13321 acaccggcag gccgtcgtcg ctgcggtcgg tgccgaagac ctcgcacacc acaccgagtt
    13381 cgaaggggtt cacaccgtcg aggagggcga cggccacgtt ctgcagcatg cccccagtgt
    13441 gcctcgtcct tggcagtaat tcgagggtct acggcagtac tgccactgac ggtaaggagc
    13501 aatcggcgcg acagtggtgt ccatgaacac gaaccagatc gaagccctga tcggactgac
    13561 cgccaccttc gggatcctgg tcctcctgat cctcccgtcc gtgttcggcc tggtgcgcga
    13621 gaggcgcatc gaccgtcaga tccgggaggc ccaggaggcc agggagagcg agccggctca
    13681 gaagtcctcg tccaggtcga cggtgccctc caccgccacc tggtacgcgg agggccgccg
    13741 ctcgaagaag ttggtcaact cctgaacccc ctggagctcc atgaaggaga aggggttctc
    13801 ggagccgtac accggagcga agccgagccg ggtgagccgc tggtcggcga cgcactccag
    13861 gtactgccgc atcgactcgg tgttcatgcc cgggaggccg tcaccgcaca ggtcgcgcgc
    13921 gaactgcagc tcggcctcga ccgcctcccg gagcatgtcc gtcacctcct gccggagctg
    13981 gtcgtcgaac agctccggct cctccttgcg gacggtgtcg accacgtcga aggcgaagga
    14041 catgtgcatc gtctcgtcgc ggaacaccca gttggtgccg gtggcgaggc cgtgcagcag
    14101 gccccggctg cggaaccagt agacgtaggc gaaggcgccg tagaagaaca gtccctcgat
    14161 gcacgcggcg aagcagatca ggttcagcag gaagcggcgg cggtccgcct gcgtctccag
    14221 ccggtccagc ttctccaccg agtccatcca cttgaagcag aacgacgcct tctcgcggat
    14281 ggacgggatg ttctccacgg ccgcgaaggc cgccgtgcgg tcctccgggt cggggagata
    14341 ggtgtcgagg agcgtcaggt agaactggac gtgcacggcc tcctcgaaga gctggcggct
    14401 cagatacagc cgcgcctcgg gggagttgat gtgcttgtac agcgtcagca ccaggttgtt
    14461 cgcgacgatc gagtcgcccg tggcgaagaa ggcgaccagg cggccgatca ggtgctgctc
    14521 cgccggtgac agcttggcga ggtcggcgac gtccgagtgg aggtcgacct cctccacggt
    14581 ccaggtgttc ttgatggcgt cccggtagcg ctcgtagaag tccgggtagc gcatggggcg
    14641 cagggtgagc tcgaagccgg ggtcgagaag gttctgggtg ctcattactg gcaggcctcg
    14701 caggactcgg ggttttccag ggagcaggcg accgcttcgg gatccggggt ggcctgcgcg
    14761 gggacggtgg cctgggcggc gcgggcgatg cgggtcgccg ggcgcgagcg caggtagtac
    14821 gtcgtcttca gcccggactt ccaggcgtag gcgtacatcg aggagagctt gccgatggtc
    14881 ggcgtctcca ggaagaggtt cagggactgg gactggtcca ggaacggggt cctggccgcc
    14941 gccatgtcga tcaggccgcg ctgcgggatc tcccacgcag tgcggtagag ggcgcgcacg
    15001 tcctcgggga tccaggcgaa gtcctgcacc gagccgctgg cctcgcgcag ggcctcccgg
    15061 ctgcgggcgt cccacacgcc gagccgcttg agctcgtcca ccaggtagga gttgacctgg
    15121 aggaactcgc ccgacagcgt ctcgcgcttg aacaggttgg acacctgcgg ctcgatgcac
    15181 tcgtacacgc ccgcgatcga ggcgatggtg gccgtggggg cgatcgcgag gagcagcgag
    15241 ttgcgcatgc cggtcgcggc gatgcgctcc cgcagcgccg cccagcgctc cggccaggtc
    15301 agctccacgt cgtagtggtc ggggtgcagc acgccccggg ccgtacgggt cttctcccag
    15361 gccggcagcg gaccgctccg ctcggcgagg tcggccgagg cctcgtacgc ggcgagcatg
    15421 atccgctcgg cgatacgggt ggagagggcc ttggcctccg gcgagtcgaa gggcaggcgc
    15481 agcttgaaga agacgtcctg aaggcccatc gcgccgaggc cgaccggacg ccagcgggag
    15541 ttggaccgcc cggcctgttc ggtcgggtag aagttgatgt cgacgacacg gtccaggaag
    15601 gtcacggcgg tgcggacggt ggcgtccagc cggtcccagt cgaggtcacc ggtcgatgtg
    15661 tcgacgaagg cgccgaggtt gaccgagccg aggttgcaga ccgccgtctc cccgtcgctg
    15721 gtgacctcca ggatctccgt gcagaggttg gaggagtgga cgacgtggcc gggctcggcc
    15781 gtctggttgg cggtgcggtt ggcggcgtcc ttgaaggtca tccagccgtt gccggtctgc
    15841 gcgagggtgc gcatcatgcg gccgtacagc tcgcgggcgg gcagggtcct cttcgccagg
    15901 cccttcgcct cggccgcccg gtacgcggtg tcgaactcct cgccccacag gtcgaccagc
    15961 tcgggcacgt ccgaggggga gaacagcgac cactgcgcgt cggcgttcac ccgccgcatg
    16021 aactcgtccg gcacccagtg cgcgaggttc aggttgtgcg tacggcgggc gtcctcgccg
    16081 gtgttgtcgc gcagctccag gaactcctcg acgtcggagt gccaggtctc caggtagacc
    16141 gcggcggcgc ccttgcggcg gccgccctgg ttcacggcgg cgaccgaggc gtccagggtc
    16201 ttcaggaacg ggacgatgcc gttggagtgg ccgttggtgc cgcggatcag cgaaccgcgg
    16261 gcgcggatac gggagtacgc gaggccgatg cccccggcgt gcttcgacag ccgcgccacc
    16321 tggtggtacc ggtcgtagat cgagtccagc tcgtccttgg gggagtcgag gaggtagcag
    16381 gacgacatct gggggtgccg ggtgccggag ttgaacaggg tgggggagga ggggaggtag
    16441 tcgagccggc tcatgagctc gtagagcgcg gccacttcgt cgacggacct ggcggtgtgg
    16501 tcctccgcta gaccggcggc gacgcgcagc atgaagtgct ggggtgtctc gacgaccttg
    16561 cgggtgaggg ggtgccggag caggtagcgg ctgtggagcg tgcgcagtcc gaagtagccg
    16621 aagcggtcgt cggcggccgg gtcgatcagg gcgtcgagcc gggccgcgtg cagccgtacg
    16681 aactcggcgg tccggtcggc gatgaggccc tcccggtgcc cgaccacgac ggactcggtg
    16741 aaggacgtga cgccctggga ggcggcctcg gcgcggatgc cgatcgtcag caggcgggcg
    16801 gccagccggg agtaagcggg gtcctcggag atcagaccgg ccgcggcctc cgtcgccagg
    16861 tcccgcaact ccgcctcgtc ggcccgcgcc gaccggccgc gcaacgcggc ggcggcgacc
    16921 cggccggggt cggtgtcggg gaggtcggcg gtcagctcgg tcagggtccg caacagcgcg
    16981 gcaccgggac cgtcgtgctg ttctgcggcg gctgagaccg gatcggctgg cgcgatggtc
    17041 acgtggggct ctccctcgct cggcacgggg gcctcgtcga gggcaggggg cagcacacga
    17101 gcgcacacgg cgtcgcgtcc accgacccac tccgcgaggc ccggacgtca gggcgcaccg
    17161 gccgggcggc cgggcgcgct gtcggcaggt cctcggactg actcccatac acgcataaga
    17221 aggcatgggc acaccgttgc gggacagttc cggattcgca ccggattccc ctgcggcgac
    17281 agcgagcatg agcatacatc ttgtgccggg tggtgaaagc acccctagat gtagtgtcgc
    17341 gacggtttca cagcgtcaac tcgtaggtga ggagagtgat gtcgggaagc tccggaatcg
    17401 ggttccagtc gcgctctggg acacggacga agccgaggcg ttcgtagatg cggtgggcgg
    17461 agtgcatggt gcgctgcgtc gacaggacga cgcggacaca gccgtccgtc gcacgggcgc
    17521 ggtcgacgca ggcgcggacg agggcctctc cggcgccgcg gccgcgggcc tcgtgggcga
    17581 cggcgagcat ccgtatctcg gcctccccgg gccgggcgat gtcggtcatg ggaccgccgg
    17641 aggggacgaa ggtgacgcca ccgaggaggt gttcgccttg ggtggccacc aggacgtccg
    17701 ccgcggcggc ccgcttggcc acgtccctga gttcgccgag gtaccagtcg ctctccccga
    17761 agtcgaggag gccgtccttc aggtaggcct gggcggtgat ctcgccgagg gcgtcgtgtt
    17821 cggcgggctt cacccgccgg atgaggatgt ccatggtccg agtgtggcgg acgggtatga
    17881 caacgggccg ccggtttctc accggcggcc cgtgtcacct gcgactcagt gcgaggtgcc
    17941 cgccgtcgcc ggcggaagct ccacctggac cccggggtcg cccgcgtccg ccgtgtagtc
    18001 ctccggcctg gtctcgtcga tgccgtcggg ggccttgacg gccttcagga cgaaggtcag
    18061 gaccaccgtc accaccacgt tcaggacgaa cgccgtgagg ccgatgtagc cgatctcgcc
    18121 gatgccgggg atctccttgg cggagccgcc gaagtgcttc tgggtgggag aggcgacacc
    18181 gtacgcggcg accgtgccgt agaccatgcc gaccgcccag cccgcgagca gcgcccagcg
    18241 gtggaaccag cgggtgaaca ggccgccgac cagcgccggg aaggtctgga ggatccagat
    18301 gccgccgagg agctggaagt tgatggcgac cgtcttgtcc atggtgagga cgaagaccag
    18361 tgcgcccacc ttcaccagca gcgagaccag cttggagacc ttggtctcct gtgcgggcgt
    18421 ggcgtcgggc ttgatgaagt ccttgtagat gttgcgggtg aagaggttcg cggccgcgat
    18481 ggacatgatg gccgcgggca cgagcgctcc gatgccgatc gccgcgaagg ccacacccgc
    18541 gaaccagtcc gggaacatgg tctcgaacag ctgcgggatc gccagctgcc cgttctgcac
    18601 cttgatcccg gccgcgatgg ccatgaagcc gagcagcgcc agcaggccca gcatcaggga
    18661 gtacagcggc aggatcgtgg tgttgcggcg gatcacctca cggctcttcg aggacagcgt
    18721 cgccgtgatg gagtgcgggt acatgaagag ggcgagcgcg gagcccagcg ccagcgtggc
    18781 gtaggtccac tggcccgtct ccggcggggc cagcgcaccg cgtggcgcgc ccgtcgccgg
    18841 gttggtctgg ctgaacgcgt cgcccgcctt ggcgaagatg tcgtcgaagc cgcccagctt
    18901 gatcgggatg tagatgatcg ccaccgcgat gacgatgtag atcagcgtgt ccttcacgaa
    18961 cgcgatcagc gcgggggccc gcagacccga cgagtacgtg tacgccgcca gcacaccgaa
    19021 ggcgatcagc agcggcaggt ccttgatgaa ccagttggtg ttctcaccgc cgccgacacc
    19081 catcacgtcc agcacggcct ggatgccgac cagctggagc gcgatgtacg gcatcgtcgc
    19141 gaggatgccg gtgagggcca cggccaggga gagccccttg gagccgaaac ggccgcgcac
    19201 gaagtcggag gtcgtgacgt acccgtgctt gtgggacacc gaccacaggc gggggaggaa
    19261 cgtgaagatc agggggtaga ccaggatggt gtacggcacg gcgaagaagc cggccgcgcc
    19321 cgccgcgtag atcgccgccg gcacggcgac gaaggtgtac gccgtgtaca ggtcaccgcc
    19381 gagcaggaac caggtgatcc aggtcccgaa cgaacggccg cccaggcccc actcgtcgag
    19441 gctgtcgttc tcggccttgc gccagcgcgc ggccaggaag cccatggccg tcacggccag
    19501 gaagaagaag atgaagacgg cgagcgcgac gccgttcacg ccgtccttca ctccgacgca
    19561 ccgcccttcg cggccgagcg ggcgcgctgg tcacgctgcc acagcttgta ggcgatcatc
    19621 gtcagcgcgg tggagatcag cacccacgcc atctggtacc agtagaagaa cgggatcccg
    19681 atgaaggccg ggtcggtctt ggcgtaggag ccgacccaca gcatggccac gaagggcgct
    19741 atgaggcaga cggcgatgac gacgcgcatc ggcgtcacca ctggccctct actggcttct
    19801 ggggcttgcg acatcaggcg gctccgtccc ctcagtgatc acctgtgtaa tgcgcaggca
    19861 atctaggtca gggtgagccg cgtacggaac ccctcgtccg taatgcggta cccaaccgaa
    19921 acccggcccc agcagcggtg gagccccgtc cttcattccg ctttcactcc gcgggccgct
    19981 tcagccgcgc gacgaacttg taccggtccc cgcggtacac cgaccgcacc cattccaccg
    20041 gctggccctc gcggtccagt gagtgccggg agagcatcag catcggcagg ccgacgtccg
    20101 tgccgagcag gccggcctcg cgcggggtgg ccagcgaggt ctctatggtc tcctcggcct
    20161 ccgcgagatg gacgtcgtag acctcggcga gcgcggtgta gagggacgtg tacttcacca
    20221 gcgaccggcg cagcgccggg aagcgcttgg cgctcaggtg ggtggtctcg atggccatcg
    20281 gctcgccgtt ggccatgcgc agccgctcga tgcgcagcac ccgtccgccg gccgtgatgt
    20341 cgagcaggcc ggccaggcgg tcgtcggcgg tgatgtagcc gacgtccagc agctgcgagg
    20401 tgggttcgag gccctgggcg cgcatgtcct cggtgtacga ggtcagctgc agagcctgcg
    20461 agaccttcgg cttggcgacg aaggtgccct tgccctggat gcgttccagc cgaccctcga
    20521 cgaccagctc ctggagcgcc tggcgcacgg tcgtgcgcga ggtgtcgaac tccgccgcga
    20581 gcgtgcgctc gggcgggacc ggcgtgccgg gcgcctgtgt gtcggtcatg tcgagcaggt
    20641 gcttcttcag gcggtagtac ttgggcacgc gtgcggtacg gacgggcgcc ccgttctcgt
    20701 tctccgcact gctgacgtcg gtgctcatgc tccgccttcc cggctcctct gccgacacga
    20761 tcccacttgt ataccgtcgg cgcctctttt ggtctagtcc acaaatccga gtggtctacc
    20821 tggagtatgc cgtgcccgcc tgggttttcg ctggcttctt acttaaaggt tcctgcatat
    20881 gtaggtcgca taacggctgg tcagagccta taccggaccc ttgacaggcc tgctggtctg
    20941 gtccaagctc cccgtactgg tctacaccat tggtccaggt cctggtgccc cacgttcacc
    21001 gcggggagca ggggggttcg tggcatccct gaggagggtg gcgtgaagcg caagctgata
    21061 tccgcgatcg gtatcgcggg catgat
//
