LOCUS NZ_GG657754 72495 bp DNA linear CON 01-MAY-2024 DEFINITION Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome shotgun sequence. ACCESSION NZ_GG657754 VERSION NZ_GG657754.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces himastatinicus ATCC 53653 ORGANISM Streptomyces himastatinicus ATCC 53653 Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group. REFERENCE 1 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D., Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Annotation of Streptomyces hygroscopicus strain ATCC 53653 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA REFERENCE 3 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Arachne v. April 2007 Genome Coverage :: 6x Sequencing Technology :: ABI ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_000158915.1-RS_2024_05_01 Annotation Date :: 05/01/2024 03:02:38 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.7 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 9,680 CDSs (total) :: 9,608 Genes (coding) :: 8,720 CDSs (with protein) :: 8,720 Genes (RNA) :: 72 rRNAs :: 4, 1 (5S, 16S) complete rRNAs :: 4, 1 (5S, 16S) tRNAs :: 64 ncRNAs :: 3 Pseudo Genes (total) :: 888 CDSs (without protein) :: 888 Pseudo Genes (ambiguous residues) :: 0 of 888 Pseudo Genes (frameshifted) :: 423 of 888 Pseudo Genes (incomplete) :: 530 of 888 Pseudo Genes (internal stop) :: 36 of 888 Pseudo Genes (multiple problems) :: 97 of 888 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 20:01:42 NOTE :: This is a single region extracted from a larger record! Orig. start :: 8995743 Orig. end :: 9068238 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to GG657754.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation was added to the scaffolds in August 2010. FEATURES Location/Qualifiers region 1..72495 /candidate_cluster_numbers="1" /candidate_cluster_numbers="2" /candidate_cluster_numbers="3" /candidate_cluster_numbers="4" /contig_edge="False" /product="NRPS-like" /product="NRPS" /product="NRP-metallophore" /region_number="34" /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)" /rules="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /rules="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /tool="antismash" cand_cluster 1..72495 /SMILES="NC([*])C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC1=CN c2c1cccc2)C(=O)O" /candidate_cluster_number="1" /contig_edge="False" /detection_rules="cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)" /detection_rules="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /detection_rules="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /kind="neighbouring" /product="NRPS-like" /product="NRPS" /product="NRP-metallophore" /protoclusters="1" /protoclusters="2" /protoclusters="3" /tool="antismash" cand_cluster 1..42988 /SMILES="NC([*])C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)O" /candidate_cluster_number="2" /contig_edge="False" /detection_rules="cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)" /kind="single" /product="NRPS-like" /protoclusters="1" /tool="antismash" protocluster 1..42988 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="False" /core_location="[20000:22988](-)" /cutoff="0" /detection_rule="cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS-like" /protocluster_number="1" /tool="antismash" proto_core complement(20001..22988) /aStool="rule-based-clusters" /tool="antismash" /cutoff="0" /detection_rule="cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS-like" /protocluster_number="1" gene complement(176..1351) /locus_tag="SSOG_RS38330" /old_locus_tag="SSOG_07604" CDS complement(176..1351) /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /GO_function="GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) GFO_IDH_MocA" /gene_functions="biosynthetic-additional (rule-based-clusters) GFO_IDH_MocA_C3" /gene_functions="biosynthetic-additional (smcogs) SMCOG1079: oxidoreductase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010353500.1" /locus_tag="SSOG_RS38330" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07604" /product="Gfo/Idh/MocA family oxidoreductase" /protein_id="WP_009719688.1" /sec_met_domain="GFO_IDH_MocA (E-value: 1.2e-23, bitscore: 83.2, seeds: 39, tool: rule-based-clusters)" /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 2.4e-26, bitscore: 91.3, seeds: 4226, tool: rule-based-clusters)" /transl_table=11 /translation="MSQDIGVAVIGAGMAGRAHAHGYRSAGTVFSAGLPPVRLVSIADL NGDLARDTAARYGFERADTSWEAVVKADDIDVVSVVVANDLHREIVRELAAAGKHVLCE KPLAPSPEDARAMITDTEKAGIVARVGFTFRRAPGIGAVREQLRSGRLGRPLHVSAQYW TDYGSDPQAPMSWRYRGGPGSGALADLGSHLTDVAEFLLGPVETVHGAALSTTITERPL PLGHVVGHAHVEVSDEREPVGNDDWASYCARFASGATGDLSVSRIAFGHPNTLKFEVFC ENGALSYDQSRPGEFAIATGDLPGGVNGFRRVIVGVEHPYIAGGMAMDANGIGVGHNDS FVYQARAFLDEVAGLEEIPRCAAFAEGLHNLDVLEAVTRSATRNTTSAVAA" gene 1501..2544 /locus_tag="SSOG_RS38335" /old_locus_tag="SSOG_07605" CDS 1501..2544 /GO_function="GO:0000976 - transcription cis-regulatory region binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_function="GO:0043565 - sequence-specific DNA binding [Evidence IEA]" /GO_process="GO:0006351 - DNA-templated transcription [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /GO_process="GO:0045892 - negative regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1078: LacI family transcription regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006374995.1" /locus_tag="SSOG_RS38335" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07605" /product="LacI family DNA-binding transcriptional regulator" /protein_id="WP_063631614.1" /transl_table=11 /translation="MAGQDRTRGNAPGGRERKPTMADVARHVGVSRALVSIVFRGAEGA SEATRQRVLEGAAALGYRRDSLARGLRSNRTRNLGILFDLRRPFEVEFVEHTYPAVEKY GYHLLLGAVTPHRNQARVVEELLTYRCEGLIVLGPEPDGDRLESIADEVPLVEVGRGVT PGRVDVVRNDDALGTRQAVDHLVHLGHRAIAHIDGGTNPGARDRRAGYREAMTDHGLAH EIRVVAGGYTDEAGATAARQLLAEGLPTAVITANDQAVIGLLDVAVRAGLRIPEDLSVI GYDDSRFLRLPGIDLTSVRQDIPAMAELAVQAAVERIELPETEPRSVALPPQLVVRNTT KTPKNAE" gene complement(2557..4527) /locus_tag="SSOG_RS38340" /old_locus_tag="SSOG_07606" CDS complement(2557..4527) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018546770.1" /locus_tag="SSOG_RS38340" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07606" /product="APC family permease" /protein_id="WP_009719690.1" /transl_table=11 /translation="MATSTDVETPPENPSGGRLRSWMLEGLADMAKRQPGPHAQPSEGH QGKRWWRVMCLTGVDYFSTLGYQPGIAALAAGLLSPIATLVLVAVTLAGALPVYRRVAK ESPHGEGSIAMLERLLSFWQGKLFVLTLLGFAATDFLITITLSAADASTHLVENPHFTS LLHGHEVAITMGLVALLGAVFLKGFTEAIGVAVALVGAYLALNAVVVIVGLWHVATAAH VVTDWSQALTAQHSNPLVMVGLALVVFPKLALGLSGFETGVAVMPHVQGDPGDTEARPT GRIRDTRKLLTTAAVIMSGFLICTSFITTLLIPQDAFKAGGPANGRALAYLAHQYLGSV FGTVYDAATIGILWFAGASALAGLLNLMPRYLPRYGMAPHWARAVRPMVLVFTLIAFLV TWIFGADVDAQGGAYATGVLVLMTSAAVAVTIAARRARQRGWTIAFGTISVVFVYTTAV NVVERPDGVKIGACFIAGIIAVSLLSRLARAFELRVTDMELDDLAERFVRDTATRRIRF IANEPDNRDPAEYRDKTQQIRADNDIPAEEDLVFVEVTVRDPSDFESAVRVRGEVLHGR YRVLTLDGSSIPNSLAALLLHVRDETGCRPHIYFEWTEGSPFAQFLRFFLFGQGEVAPV TREVLREAEPDRARRPHVHVG" gene 4812..5372 /locus_tag="SSOG_RS38345" /old_locus_tag="SSOG_07607" CDS 4812..5372 /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1057: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014172694.1" /locus_tag="SSOG_RS38345" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07607" /product="TetR family transcriptional regulator" /protein_id="WP_009719691.1" /transl_table=11 /translation="MSAPARRTDAVQNRTRIVEAARAALAESRHVHLNEIAKRAGVGQG TLYRNFPNREALLAEVYRRDVEELVSAASALLAEHEPVEALRHWLDRVIDYAEIKRGVL AALEPVAWQDLVAHSHNPIEGALAQLLDAGKAAGSLRTDVDAHGALLLIAYLGRLERGE WESTARPLMNVILDGLRRPDADR" cand_cluster 5049..>69935 /SMILES="NC([*])C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC1=CN c2c1cccc2)C(=O)O" /candidate_cluster_number="3" /contig_edge="False" /detection_rules="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /kind="single" /product="NRPS" /protoclusters="2" /tool="antismash" protocluster 5049..>69935 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="False" /core_location="[25048:>49935](+)" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS" /protocluster_number="2" /tool="antismash" proto_core 25049..>49935 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS" /protocluster_number="2" gene 6146..6439 /locus_tag="SSOG_RS55160" /old_locus_tag="SSOG_07608" CDS 6146..6439 /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS55160" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_07608" /product="hypothetical protein" /protein_id="WP_208867408.1" /transl_table=11 /translation="MLVAARTAVAGAPLWATIGAHLTFLTINRAVLEGNERDAGVSVDQ TTPDAVLLVPAYLLVATVAFLAYGRIARRGSLTASSDLPRPDGQPYVRHHGG" gene 6429..7121 /locus_tag="SSOG_RS38355" /old_locus_tag="SSOG_07609" CDS 6429..7121 /GO_function="GO:0004177 - aminopeptidase activity [Evidence IEA]" /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /GO_process="GO:0006508 - proteolysis [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018567824.1" /locus_tag="SSOG_RS38355" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07609" /product="M24 family metallopeptidase" /protein_id="WP_039942419.1" /transl_table=11 /translation="MADDEHTRAARLLEAQAKAERLFAEVEERGLLAPGEGERAVSDRI RDLANEMFGTTRHWHKRIVRSGPNTLMPYRENPPDRVIGADDIVFADFGPIFEEYEADF GRTFVLGDDPVKQRLRDDLAEVFAAGKRYFESDPDITGKRLHAEVERLATEAGWELGGW HAGHLVGEFPHETIDGADTESYITPANDTPLRRTDKSGRHCHWIQEIHLVDRERGFGGF YEQLLTLS" gene complement(7254..8207) /locus_tag="SSOG_RS38360" /old_locus_tag="SSOG_07610" CDS complement(7254..8207) /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_function="GO:0043565 - sequence-specific DNA binding [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1287: AraC family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019356930.1" /locus_tag="SSOG_RS38360" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07610" /product="AraC family transcriptional regulator" /protein_id="WP_009719694.1" /transl_table=11 /translation="MDAFSDLIRGVRAHGSLFGSSTLTPPWALHFVDGAPLTLCTVLTG AGWIVPEGRPPELLRARETIVVRGPATFTFVDELHTPAEPLACGEHCATPEQGGTRHRL GWNDCGEDDAGDGRGATTLIVGAYPVRGEISRRLLDALPVVLRVGAGGTADAVLDHVAA EVAVDTPGQQVVLDRLLDWMLVCTLREWFDRPGGEPPAWWAAQRDPVVGDALRLLHAEP AAPWTVAALADRTGVSRSTLAKRFADLVGEPPLTYLTRWRMTLAADLLVEQEAATIADI ARTVGYADPFGFSAAFKRVRGANPSEFRRTATGSNA" gene 8304..9137 /locus_tag="SSOG_RS38365" /old_locus_tag="SSOG_07611" CDS 8304..9137 /codon_start=1 /gene_functions="other (smcogs) SMCOG1199: NmrA family protein" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010358978.1" /locus_tag="SSOG_RS38365" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07611" /product="NAD(P)H-binding protein" /protein_id="WP_009719695.1" /transl_table=11 /translation="MSNSNDTTLVLGATGKTGRRVAARLRLRGTPVRAASRSSRTRFDW SDPGGWDAALRDVAAVYVVAPQVPGPVHEFVARAEAAGVRRLVLLSGHGADTWGDSTFG LDMRSAEDAVRGSALEWTVLRPSNFAQNFDEDVFHAPLVAGELALPAGAVPEPFIDVED VADAAAAVLTEPGRHAGRIYELTGPRAITFGEAVELISRASGRALTYRRISPAEYAATL VGEGLSEDDAHHVAEMFVMMERGLIAATTDDLATLLGRAPRTFEDYVVRAAAAGA" gap 9214..9313 /estimated_length=unknown gene complement(<9314..9754) /gene="merB" /locus_tag="SSOG_RS38370" CDS complement(<9314..9754) /EC_number="4.99.1.2" /GO_function="GO:0018836 - alkylmercury lyase activity [Evidence IEA]" /GO_process="GO:0046413 - organomercury catabolic process [Evidence IEA]" /codon_start=1 /gene="merB" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020554704.1" /locus_tag="SSOG_RS38370" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="organomercurial lyase" /protein_id="WP_245606470.1" /transl_table=11 /translation="MPELAALTELTADEVRRELRALALHDSHDVVLDPRDHDRVVMAHP FASVPLGFSVMGAHTLWWGGCAWDSFALPHLLRDEPDVLVATRCPACDTPHAWVVGRAA PPHGDQVAHVLTPMHRAWDDVVPPASPPARTPGALEPGYTRRD" misc_feature 9823..9838 /note="TFBS match to LexA_variant_1, Repressor of DNA damage response, confidence: weak, score: 21.42" /tool="antismash" misc_feature 10010..10025 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 18.71" /tool="antismash" gene 10011..>10939 /locus_tag="SSOG_RS38375" /old_locus_tag="SSOG_07612" CDS 10011..>10939 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF013335.4" /locus_tag="SSOG_RS38375" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07612" /product="nucleoside hydrolase" /protein_id="WP_039942422.1" /transl_table=11 /translation="MRKIILDCDPGHDDAIAMLLAHGNPDVELVAVTTVVGNQTLEKVT RNALSVARIANITGVPFAAGCPRPLVRTAETAAGIHGESGIDGPAMPEPTLALDPRHAV DLIIDTVMAHEPGEITLVPTAGLTNIALAVRKEPRIAQRVREVVLMGGGYHTGNWSPVA EFNIKIDPEAAHIVFNESWPVTMVGLDLTHQALATPQVVDRIARVGTGPATFVNELLEF FGAMYLKEQGFEHPPVHDPCAVAYVIDPAVMTVRKAPVDIELTGTLTLGMTVTDLRAPA PDDCHTQVAVTLDHQRFWDLIVDALERIG" gap 10940..11039 /estimated_length=unknown gene 11145..12477 /locus_tag="SSOG_RS38380" /old_locus_tag="SSOG_07613" /pseudo="" CDS 11145..12477 /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018530798.1" /locus_tag="SSOG_RS38380" /note="frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07613" /product="MFS transporter" /pseudo="" /transl_table=11 /translation="MLSPALKSIEDSLGATSAEGGPEADRVLHLGGPLLALPAPPGRPH RPPQGPGRNAGADGRRLCDGGARRERPRALRGPRHPGRIRTHRAALPDHAAQRGPRAEE VRHPPRRHHRRQRRRRRCRLPRGRIPRRPPWLLVHLLGHGRRRRARHRPGRHPHPRVGR HRVRGS" gene 12474..12656 /locus_tag="SSOG_RS38385" /old_locus_tag="SSOG_07614" CDS 12474..12656 /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS38385" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_07614" /product="hypothetical protein" /protein_id="WP_009719698.1" /transl_table=11 /translation="MTLTTRHPLMVKRGVLAGALPVIWVLRWRPPRILDRIYAWAYVGL LTVVMAAMALSGVSG" gene 12734..13540 /locus_tag="SSOG_RS38390" /old_locus_tag="SSOG_07615" CDS 12734..13540 /EC_number="2.7.7.-" /GO_function="GO:0016779 - nucleotidyltransferase activity [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017945674.1" /locus_tag="SSOG_RS38390" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07615" /product="nucleotidyltransferase domain-containing protein" /protein_id="WP_039939695.1" /transl_table=11 /translation="MSERGLDHDGTIAREGALDRVPTAFVPVVDAARAHITGTFGGTRL HSAYLYGSIPRGTATPGVSDLDLQLALHDEPTEADRADVTAIETALDRAFPQINGAGIL VSSARFLLSGIERHDAGFFIACLCTPLLGPDLAEQLPRYRPTSLLARETNGDFARLLPH WRAKAAEAATDAERRSFGRRVGRRTVRTGFTLVMPRWGGWTSDLDQSAELFGRYYPERA EQMRAAASMGRTPSPDPAVLGMLIDDLGPWLAAEYTAVHGERAPRP" gene complement(13554..14150) /locus_tag="SSOG_RS38395" /old_locus_tag="SSOG_07616" CDS complement(13554..14150) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020551392.1" /locus_tag="SSOG_RS38395" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07616" /product="TetR/AcrR family transcriptional regulator" /protein_id="WP_009719700.1" /transl_table=11 /translation="MPTGVAIRDVRDQLFDAAERILLRDGPSALTSRAVTTEAGCAKGV LHRHFADFDAFLAELVLDRIARIDDLAAALRASAGTGTVADNLTQALMDVFGAVAVAIV SLVTSRDDLRSRLREVRPTGVPILTEAAIAIASYLTAERERGRITADADVDTLAPTLIG AAHMLFADRHGTPPEPGAVRKVVTAVMAGVEHEAP" misc_feature complement(14210..14226) /note="TFBS match to GnfM, Regulator of nitrogen-fixation genes, confidence: weak, score: 20.34" /tool="antismash" gene 14274..15038 /locus_tag="SSOG_RS38400" /old_locus_tag="SSOG_07617" CDS 14274..15038 /GO_function="GO:0008168 - methyltransferase activity [Evidence IEA]" /GO_function="GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1089: methyltransferase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003981737.1" /locus_tag="SSOG_RS38400" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07617" /product="methyltransferase domain-containing protein" /protein_id="WP_039939697.1" /transl_table=11 /translation="MAESFGSDAERYDRARPRYPQALVDRIVAAGPGPDVLDVGCGTGI VARQFAEAGSRVLGVEVDARMADLARRRGIDVEVASFEDWDPADRRFDAVVSGQTWHWV DPLAGPAKAAQALRPRGLLALFWNAAQPSPELTEAFTDVYRRVIPDSIAVRQWAVPAAE GYTALCAQTADRMREVGAFTDPEQWRFDWEQPYTRDEWLDQLPTQGAFTRLPQAELDEV LAGVGTAIDAAGGSFTMHYATVAVAATRTDSA" gene 15094..15837 /locus_tag="SSOG_RS38405" /old_locus_tag="SSOG_07618" CDS 15094..15837 /GO_function="GO:0008168 - methyltransferase activity [Evidence IEA]" /GO_function="GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014056189.1" /locus_tag="SSOG_RS38405" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07618" /product="methyltransferase domain-containing protein" /protein_id="WP_009719702.1" /transl_table=11 /translation="MATYDTLGATYARTRRPDPRIAAQIHAALGDVTDVINVGAGTGSY EPPRTVLAVEPSRVMLAQRPSGSAPAVRAVAERLPLGDDAADAVLAVLTVHHWTDLTAG IRELRRVARRRIVVLTWDQRIFRERFWLVRDYLPEAAAFDDTRAVPTEQLAALLGGARR EPVLVPHDCSDGFAAAYWRRPHAYLDPQVRAGISLLAQTGETVTAPGLARLADDVATGR WHLRHAELLGLEAIDVGYRLLVTDL" gene complement(15817..16173) /locus_tag="SSOG_RS38410" /old_locus_tag="SSOG_07619" CDS complement(15817..16173) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS38410" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_07619" /product="hypothetical protein" /protein_id="WP_039939700.1" /transl_table=11 /translation="MDFTPHADYLRHEPVAIADITGKAPGGSTPAGHIRLRFADAHSLE AAMTAFGPVTRDDEALAVYIPTDGGIPALRAVLDTLDSASIEAEALTVHTPDLDDIALA LTGPMRAASEVGHQ" gene complement(16206..17174) /gene="argB" /locus_tag="SSOG_RS38415" /old_locus_tag="SSOG_07620" CDS complement(16206..17174) /EC_number="2.7.2.8" /GO_function="GO:0003991 - acetylglutamate kinase activity [Evidence IEA]" /GO_process="GO:0006592 - ornithine biosynthetic process [Evidence IEA]" /codon_start=1 /gene="argB" /gene_functions="biosynthetic-additional (smcogs) SMCOG1174: acetylglutamate kinase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010471976.1" /locus_tag="SSOG_RS38415" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07620" /product="acetylglutamate kinase" /protein_id="WP_009719704.1" /transl_table=11 /translation="MTASAAQALPARHSAASGRKDRLTVIKLGGNAMVDGELEASFADD VVRMHRAGLQPVVVHGGGPQISAELERHGLTATFRGGLRVTTPRAMGVVRMVLAGRVQR ELVGLINRHGPLAVGMTGEDADTVTAVRHLPVIEGRPVDIGRVGEISAVDTTLLRTLLA DGRIPVVSPIARSADDDGIYNVNADTAAAALASALGAGELLLLTDVQGLYADWPDSHEV IERLTATELEALLPELSHGMTPKMAACLHAVRHGVDRARVLDGRVRHAALAGLRPDERS GTTVVPDAKPSPIDRMAPHMASRNSTCAYGPQGSSDERTDP" misc_feature complement(17106..17108) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" misc_feature complement(17148..17150) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene 17413..18057 /locus_tag="SSOG_RS38420" /old_locus_tag="SSOG_07621" CDS 17413..18057 /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) KtzT" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016641415.1" /locus_tag="SSOG_RS38420" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07621" /product="FMN-binding negative transcriptional regulator" /protein_id="WP_009719705.1" /sec_met_domain="KtzT (E-value: 1.7e-115, bitscore: 382.8, seeds: 5, tool: rule-based-clusters)" /transl_table=11 /translation="MFVPSHYREPDSSWMVDIIRGNPLALMMSNGAAGEPPFATHLPVI PDPAMTGDWSERLSEATLLGHMNRDNPQWQALEDGAVVRIAFSGPHAYVSPTLYGVTPA APTWNFTSVHVRGVVERIPSTEETLEVVKSTVRAFEADFGEGWDMAASIDYFRKIVPGV GAFRIMVRNVDGMFKLSQEQQPEVRDRVRKSFAGRECGRHQETAAYMSRLP" gene complement(18129..18374) /locus_tag="SSOG_RS56790" CDS complement(18129..18374) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS56790" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /product="hypothetical protein" /protein_id="WP_050800095.1" /transl_table=11 /translation="MGWTTKQLRHALRLAREDDINHGRATEPTRQLAVPGNRLQWWHKA AELSGTDLEQWVLATLDRAAERALEEVVEEPQEISG" gene complement(<18470..18820) /locus_tag="SSOG_RS56795" /pseudo="" CDS complement(<18470..18820) /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) LmbU" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF038070.1" /locus_tag="SSOG_RS56795" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /product="antibiotic biosynthesis protein" /pseudo="" /sec_met_domain="LmbU (E-value: 3.3e-41, bitscore: 140.2, seeds: 21, tool: rule-based-clusters)" /transl_table=11 /translation="MMNQSSDLDRPKVVLFGKRPDAERQRRTGPADTRGQVLTTNVGLR IPVGLTFDDWERAGRQLSSIVNSSSWWLGDWLVYGKHHYTDRYQRGIRTAGLQYQTLRN YAWVSRRFELHRR" misc_feature complement(18832..18845) /note="TFBS match to ArgR, Regulator of arginine biosynthesis genes, confidence: weak, score: 17.42" /tool="antismash" gene complement(19378..19935) /locus_tag="SSOG_RS38430" /old_locus_tag="SSOG_07623" CDS complement(19378..19935) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003962649.1" /locus_tag="SSOG_RS38430" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07623" /product="hypothetical protein" /protein_id="WP_039939702.1" /transl_table=11 /translation="MELMRYVDDLRQELITAAEAGDARTREVAERLVAPLSASVRLVLL DALSAAADEITRELAPGAVEVRLRGLDPGFVVTLPPSEEPSDESARPFAQPFNGTPPLA PPDAPAAPGAPGAKDGATARVNFRPPEQLKARIEEAASREGLSVNAWLVRAASAMLHHE DPGRRSERRAPQVSQNYTGWVK" gene complement(20001..22988) /locus_tag="SSOG_RS38435" /old_locus_tag="SSOG_07624" CDS complement(20001..22988) /NRPS_PKS="Domain: AMP-binding (386-782). E-value: 1.2e-105. Score: 345.4. Matches aSDomain: nrpspksdomains_SSOG_RS38435_AMP-binding.1" /NRPS_PKS="Domain: PP-binding (913-976). E-value: 1.8e-12. Score: 39.4. Matches aSDomain: nrpspksdomains_SSOG_RS38435_PP-binding.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRPS-like: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS-like: PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015577681.1" /locus_tag="SSOG_RS38435" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07624" /product="non-ribosomal peptide synthetase" /protein_id="WP_106516524.1" /sec_met_domain="AMP-binding (E-value: 6.6e-109, bitscore: 363.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1.6e-11, bitscore: 43.6, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MATHTGTPPHPNHRTRPDAAPVPDAAPPPGAGHPVLPSRRHLSGQ GRFCHALIADLPGPVDAGTLRRRLADAARRWGLTTEPRLHETAVPAPGDAPAARERLHR EALRPVRAELSPLRAVLLSYGDGSAHLVLVGVRGRVTRTALERLADVMVTGAAAGPEAP YSGAGSALPPAARWTPVDWGLGDPAARGIVSARPLTLPRAALSGHQLLGAAALATARYQ GEPTAEIGHLDTRPGAPEGARVRTVAVDEDLTPAGFLARLGGAPEQAAPEPPAVGLVVS DPAADGRTRLPALAPVFPLSLHCAERPDGTVEAAAWYDEGVIAPGVAEWFCRSVEHAAA QLAAGGDSAPLAALPVLPAEAAREVLRLGGAERDGEPEGGERIDRRFEAVASRRPDAVA LVDEHEELTYRQLNERADAMASGLHGLGIAPGTMVGVCLDRTASLVVALLAVLKAGCAY VPMDYRHPEDRLRYTAENAGLPLVIGEPGRFPATPGVRVVGVDELGRTPAAAAARRTSP DEAAYVIYTSGSTGRPKGVVVPHRNVTALLAATSADFGLGPDDVWTLFHSSAFDFSVWE IWGCLLTGGRLVVVPYWTARDTDEFHRLLAERRVTVLNQTPSAFAQLVRADRTTPRELS VRLLVFGGEPLDVRVLAPWFARHSPTWCRAVNMFGITETTVHVTAQTVTPAELVAGSRS VGRPLPGWFLSVRDAKGRVLPPGAAGEIYVGGAGVADRYLGQPELTAQRFVVDEATGER LYRSGDKGRLHPDGSLDHLGRLDNQVKIRGYRIELDEIRSVLAGDPAVSAAVVVAGQAT PGDSASSRIDAYVVLDERHGPAADTGRLLANARRILPDYMVPSTLTVIPAVPLTPNGKP DVAQLPPPAVHDRAAGRASADGGRTDEAAGTAGTAPADGVAREILEIWGQALRTPVTHE DNFFELGGNSLLVVHVLTTLRERGLPGVPLRDFYAHSTAGEFIRLVEGLHTDAVADGDA VPVPRG" aSDomain complement(20061..20249) /aSDomain="PP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38435_PP-binding.1" /evalue="1.80E-12" /label="SSOG_RS38435_PP-binding.1" /locus_tag="SSOG_RS38435" /protein_end="976" /protein_start="913" /score="39.4" /tool="antismash" /translation="EILEIWGQALRTPVTHEDNFFELGGNSLLVVHVLTTLRERGLPGV PLRDFYAHSTAGEFIRLV" aSModule complement(20061..21830) /complete /domains="nrpspksdomains_SSOG_RS38435_AMP-binding.1" /domains="nrpspksdomains_SSOG_RS38435_PP-binding.1" /locus_tags="SSOG_RS38435" /monomer_pairings="X -> X" /starter_module /tool="antismash" /type="nrps" CDS_motif complement(20616..20678) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38435_0005" /evalue="1.70E-10" /label="NRPS-A_a8" /locus_tag="SSOG_RS38435" /protein_end="791" /protein_start="770" /score="32.9" /tool="antismash" /translation="HLGRLDNQVKIRGYRIELDEI" aSDomain complement(20643..21830) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38435_AMP-binding.1" /evalue="1.20E-105" /label="SSOG_RS38435_AMP-binding.1" /locus_tag="SSOG_RS38435" /protein_end="782" /protein_start="386" /score="345.4" /specificity="substrate consensus: X" /tool="antismash" /translation="FEAVASRRPDAVALVDEHEELTYRQLNERADAMASGLHGLGIAPG TMVGVCLDRTASLVVALLAVLKAGCAYVPMDYRHPEDRLRYTAENAGLPLVIGEPGRFP ATPGVRVVGVDELGRTPAAAAARRTSPDEAAYVIYTSGSTGRPKGVVVPHRNVTALLAA TSADFGLGPDDVWTLFHSSAFDFSVWEIWGCLLTGGRLVVVPYWTARDTDEFHRLLAER RVTVLNQTPSAFAQLVRADRTTPRELSVRLLVFGGEPLDVRVLAPWFARHSPTWCRAVN MFGITETTVHVTAQTVTPAELVAGSRSVGRPLPGWFLSVRDAKGRVLPPGAAGEIYVGG AGVADRYLGQPELTAQRFVVDEATGERLYRSGDKGRLHPDGSLDHLGRLDNQVKIR" CDS_motif complement(20757..20846) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38435_0004" /evalue="5.50E-15" /label="NRPS-A_a6" /locus_tag="SSOG_RS38435" /protein_end="744" /protein_start="714" /score="47.5" /tool="antismash" /translation="PPGAAGEIYVGGAGVADRYLGQPELTAQRF" CDS_motif complement(21231..21257) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38435_0003" /evalue="5.60E+01" /label="NRPS-A_a2" /locus_tag="SSOG_RS38435" /protein_end="586" /protein_start="577" /score="-1.6" /tool="antismash" /translation="WGCLLTGGR" CDS_motif complement(21369..21428) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38435_0002" /evalue="5.30E-11" /label="NRPS-A_a3" /locus_tag="SSOG_RS38435" /protein_end="540" /protein_start="520" /score="34.2" /tool="antismash" /translation="AYVIYTSGSTGRPKGVVVPH" CDS_motif complement(21603..21644) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38435_0001" /evalue="5.90E-06" /label="NRPS-A_a2" /locus_tag="SSOG_RS38435" /protein_end="462" /protein_start="448" /score="19.3" /tool="antismash" /translation="LAVLKAGCAYVPMD" misc_feature complement(21891..21893) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene complement(23071..23901) /locus_tag="SSOG_RS38440" /old_locus_tag="SSOG_07625" CDS complement(23071..23901) /NRPS_PKS="Domain: PKS_KR (8-179). E-value: 3.8e-09. Score: 28.6. Matches aSDomain: nrpspksdomains_SSOG_RS38440_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (smcogs) SMCOG1001: short-chain dehydrogenase/reductase SDR" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010984630.1" /locus_tag="SSOG_RS38440" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07625" /product="SDR family oxidoreductase" /protein_id="WP_009719709.1" /sec_met_domain="adh_short (E-value: 3.2e-32, bitscore: 111.1, seeds: 230, tool: rule-based-clusters)" /transl_table=11 /translation="MGTSLQGKTVVITGAARGIGRECAVRFADEGADLALLDIAGDLDA VGYPLGSRSQLGHTAELCERRGSAVVAAAVDVRDTAQVDAAVKEALGRFHTVDVLVNNA GIAAPSGLVLHEISESDWSLMLDVDLTGAWRMMRAVAPVMVAQRSGSIINVSSTAGLVG YRNFSGYVTAKHGLIGLTKAAALDYAPHRVRVNALCPGSVRDNPLVEGRMLAEIAHSLD VPAGEYEELFLRDQPMNTLIETSDIAGAATWLAGDDSRQVTGAVITVDGGFTSR" aSDomain complement(23365..23877) /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38440_PKS_KR.1" /evalue="3.80E-09" /label="SSOG_RS38440_PKS_KR.1" /locus_tag="SSOG_RS38440" /protein_end="179" /protein_start="8" /score="28.6" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C2" /tool="antismash" /translation="TVVITGAARGIGRECAVRFADEGADLALLDIAGDLDAVGYPLGSR SQLGHTAELCERRGSAVVAAAVDVRDTAQVDAAVKEALGRFHTVDVLVNNAGIAAPSGL VLHEISESDWSLMLDVDLTGAWRMMRAVAPVMVAQRSGSIINVSSTAGLVGYRNFSGYV TAKHGLIG" CDS_motif complement(23806..23877) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38440_0001" /evalue="1.30E-05" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38440" /protein_end="32" /protein_start="8" /score="17.8" /tool="antismash" /translation="TVVITGAARGIGRECAVRFADEGA" gene complement(23916..24614) /locus_tag="SSOG_RS38445" /old_locus_tag="SSOG_07626" CDS complement(23916..24614) /NRPS_PKS="Domain: Thioesterase (6-230). E-value: 2e-38. Score: 125.0. Matches aSDomain: nrpspksdomains_SSOG_RS38445_Thioesterase.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Thioesterase" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004: thioesterase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019356277.1" /locus_tag="SSOG_RS38445" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07626" /product="alpha/beta fold hydrolase" /protein_id="WP_009719710.1" /sec_met_domain="Thioesterase (E-value: 1e-34, bitscore: 119.8, seeds: 16, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 3.5e-07, bitscore: 30.2, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MPSQPFPLVCLPFAGSGAGFYRAWTEGPDRGIKVIPVQLPGREEL FLDTPFTDALEAAAQLAPQIAELTAEFPAFGLFGHSLGAVLCYEIARELQRLGHPGPSH LYVSGSPGPWNGRDSRATGLNDEEFLERVQEFAGYRHAAFDNPDLRELLLPVLRADVAM HENYKPSSDEPLGLPVTSIRGETDALVSREHAQQWRDVTRDAFRYVELPGGHMYLADAA EALLRTIAER" aSDomain complement(23925..24596) /ASF="active site serine inconclusive" /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38445_Thioesterase.1" /evalue="2.00E-38" /label="SSOG_RS38445_Thioesterase.1" /locus_tag="SSOG_RS38445" /protein_end="230" /protein_start="6" /score="125.0" /tool="antismash" /translation="PLVCLPFAGSGAGFYRAWTEGPDRGIKVIPVQLPGREELFLDTPF TDALEAAAQLAPQIAELTAEFPAFGLFGHSLGAVLCYEIARELQRLGHPGPSHLYVSGS PGPWNGRDSRATGLNDEEFLERVQEFAGYRHAAFDNPDLRELLLPVLRADVAMHENYKP SSDEPLGLPVTSIRGETDALVSREHAQQWRDVTRDAFRYVELPGGHMYLADAAEALLRT IA" CDS_motif complement(24333..24386) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38445_0001" /evalue="3.90E-07" /label="NRPS-te1" /locus_tag="SSOG_RS38445" /protein_end="94" /protein_start="76" /score="22.6" /tool="antismash" /translation="LFGHSLGAVLCYEIAREL" misc_feature complement(24825..24842) /note="TFBS match to HipB, Bacterial antitoxin HipB, confidence: weak, score: 19.59" /tool="antismash" gene 25049..31225 /locus_tag="SSOG_RS38450" /old_locus_tag="SSOG_07627" CDS 25049..31225 /NRPS_PKS="Domain: AMP-binding (31-438). E-value: 5e-109. Score: 356.5. Matches aSDomain: nrpspksdomains_SSOG_RS38450_AMP-binding.1" /NRPS_PKS="Domain: PCP (552-618). E-value: 3.3e-24. Score: 76.9. Matches aSDomain: nrpspksdomains_SSOG_RS38450_PCP.1" /NRPS_PKS="Domain: Epimerization (643-946). E-value: 2.4e-114. Score: 374.6. Matches aSDomain: nrpspksdomains_SSOG_RS38450_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (959-1128). E-value: 4.1e-35. Score: 112.8. Matches aSDomain: nrpspksdomains_SSOG_RS38450_TIGR01720.1" /NRPS_PKS="Domain: Condensation_DCL (1137-1427). E-value: 5.6e-90. Score: 293.4. Matches aSDomain: nrpspksdomains_SSOG_RS38450_Condensation_DCL.1" /NRPS_PKS="Domain: PCP (1977-2042). E-value: 1.3e-25. Score: 81.4. Matches aSDomain: nrpspksdomains_SSOG_RS38450_PCP.2" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127: condensation domain-containing protein" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:NF012873.4" /locus_tag="SSOG_RS38450" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07627" /product="non-ribosomal peptide synthetase" /protein_id="WP_009719711.1" /sec_met_domain="AMP-binding (E-value: 1.2e-114, bitscore: 382.2, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 4.5e-53, bitscore: 179.4, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1.1e-15, bitscore: 57.0, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MDVHDPLERSLPLTAADDTAGRILGSTVPALFARQVRLAPDAVAV VSGDEELTYGELDARAGRLARGLVRRGVGPESLVAVALPRSAESVVALLAVLKSGAAYL PMDPGYPAERVGFMLRDARPALLLTADGTAPGDPGRCPAVTPAELEDEGAAGEPDDTAG EPDDTAGEPDGARHTAGLAYVIYTSGSTGTPKGIGVTHRDVVALATDRRWHGGAHDRVL LHSPLAFDASVYEIWVPLLRGGRIVVDPSTDLTPGVLAELVARHRVTALWLTSALFDLL VEEDVRCLTGLREVWVGGDRVSPRSVRRAVAACPGTVFVNGYGPTETTVFATSHRIDPD ATGDAEVPIGRPLDTLRAHVLDDRLRPVPPDATGELYVAGDGVARGYLHRGALTAERFV ACPFGAPGERMYRTGDLVTRNADGDLVYQGRADTQVKVRGFRIEPGEIESALLTHPAVA HAAVIVRQDRGAGTARHLVGYVVPARDDGPAPARTALPDELREHVARRLPEFMVPSAFV LLDRLPLTPNGKLDRAALPVPHLTGAAYRAPRPGTEETLAGIFTEVLGRARVGADDDFF ALGGDSIQSIQLVSRARAQGVAVSSRQIFEHRTVASLARAADTAVELGPAPVLAEFDGG GTGHQPLMPVARWIQETGPGFDSLLQAVVLELPPGIDRDGLAATLAAVVDRHDLLRATL RDDGLFVGPPGSVDVRPLIRDVACDGQWSGEPWRHLLVTELRALATRLDPAAGTVAQFV WFRPPSGPGRLLAGLHHMVVDGVSWRILMPDLAAAWKHVRAGTAPGLPAPVTSVRRWAH ALTDEARAAGRVAELPRWTSIVDGPDPVLGTRRLDPAVDVQSTVEKVRVLLPAPATEAL LTAVPAAFHGGVNDVLLAGLAMAVARWRRARGVDEPSTLLRLEGHGREEESVPGADLSR TVGWFTSVFPVRLDLGGIDLDEAFTGGPAAGDAVKAVKEQLLAVPGKGLGYGLLRYLNP ETAEVLRTRSMGQIGFNYLGRFSAADMPEELRGLGWTQTAELAEFTELAELDAGHDPAM PALSEVDINATVTDTPAGPRLGAVFGAPTGVLSPAEVRELAELWQRALEALVRHTGRPG AGGLTPSDVPLVSVAQDELTAWEKRHPGLVDVWPLTPLQAGMLHHAQLAGADTYQVQLL FGFDGPVDARRMRAAGQALLDRHPSLRTAYLPDAAGDTVQLVVSDVALPWRERALPEAE FERFLAEDRAVPFDTATPPLLRMTLVRVGADRTELLLTAHHVLFDGWSEPLLLRDLLWL YADPAALPEAPSFRDFLGVLAHRDRERSVRAHTDALDGIAGPTLLVPDRPDTDVDHDAV GSGFGEVELPVTADEARALALRAAETGTTLNTVLQASWAVVLAELTGSPDVLFGTTVSG RPPALAGVDTTVGLFINTLPVRARCAPGKTLAEVAAELQAAQAALLEHHDCGLTEIHEA TGFGALFDTLVVFQSYPFDSAGIAEASGAAGLPVPAFRNIAGSHYPVVVMADQDPELRL RLQYTNGALDRAAASALGDRLLRALRAFLADPHGRVGAVDVLTPQERHLPAVPAAPGES VPELFARLAAGDPDAVALDVAGATTGRGELDRRADRLADELLRGGVVPGSVVAVCASDP VDRVVALLAVMRAGGCALPMDPEDSPAWSDRVLRHAEAVAVVLDKEADGLPWGDLPRIR LAPATVDSGPAAPGTARPRPGHLALIDCTADAAGRPYGVVVTRAGLAAGIGRFAPDAPA EDAPLVTGPATPAADLLLALCAGRRVEVREGAPETRPVHADPARVRVLSPSLAPAAPGA VGELYVAGAYGHGCAGPGPGPVTAERFVADPYGPAGSRMYRTGVRGRITADGRVEETDG SGGTGRRAAETVLLTHPSVAHAAVVPSPSGGGDGDTGYVVATEGARIALDELRAFTRAR LPHRLVPRSLVVLDALPTTASGRLDPRRLPDVAGAPRRTAGNAREETLTRLFTEVLGRE RIGVDDDFFALGGNSLLATRLIGRIRHELAVEVSIRSVFQHATIAELAAHWDEITTASG PRLRKRS" aSDomain 25142..26362 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_AMP-binding.1" /evalue="5.00E-109" /label="SSOG_RS38450_AMP-binding.1" /locus_tag="SSOG_RS38450" /protein_end="438" /protein_start="31" /score="356.5" /specificity="substrate consensus: Val" /tool="antismash" /translation="FARQVRLAPDAVAVVSGDEELTYGELDARAGRLARGLVRRGVGPE SLVAVALPRSAESVVALLAVLKSGAAYLPMDPGYPAERVGFMLRDARPALLLTADGTAP GDPGRCPAVTPAELEDEGAAGEPDDTAGEPDDTAGEPDGARHTAGLAYVIYTSGSTGTP KGIGVTHRDVVALATDRRWHGGAHDRVLLHSPLAFDASVYEIWVPLLRGGRIVVDPSTD LTPGVLAELVARHRVTALWLTSALFDLLVEEDVRCLTGLREVWVGGDRVSPRSVRRAVA ACPGTVFVNGYGPTETTVFATSHRIDPDATGDAEVPIGRPLDTLRAHVLDDRLRPVPPD ATGELYVAGDGVARGYLHRGALTAERFVACPFGAPGERMYRTGDLVTRNADGDLVYQGR ADTQVKVR" aSModule 25142..28432 /complete /domains="nrpspksdomains_SSOG_RS38450_AMP-binding.1" /domains="nrpspksdomains_SSOG_RS38450_PCP.1" /domains="nrpspksdomains_SSOG_RS38450_Epimerization.1" /domains="nrpspksdomains_SSOG_RS38450_TIGR01720.1" /locus_tags="SSOG_RS38450" /monomer_pairings="Val -> D-Val" /starter_module /tool="antismash" /type="nrps" CDS_motif 25328..25369 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0001" /evalue="1.00E-04" /label="NRPS-A_a2" /locus_tag="SSOG_RS38450" /protein_end="107" /protein_start="93" /score="15.6" /tool="antismash" /translation="LAVLKSGAAYLPMD" CDS_motif 25592..25651 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0002" /evalue="3.10E-09" /label="NRPS-A_a3" /locus_tag="SSOG_RS38450" /protein_end="201" /protein_start="181" /score="28.9" /tool="antismash" /translation="AYVIYTSGSTGTPKGIGVTH" CDS_motif 26108..26137 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0003" /evalue="5.60E+00" /label="Cy2" /locus_tag="SSOG_RS38450" /protein_end="363" /protein_start="353" /score="0.1" /tool="antismash" /translation="DTLRAHVLDD" CDS_motif 26153..26242 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0004" /evalue="1.00E-14" /label="NRPS-A_a6" /locus_tag="SSOG_RS38450" /protein_end="398" /protein_start="368" /score="46.6" /tool="antismash" /translation="PPDATGELYVAGDGVARGYLHRGALTAERF" CDS_motif 26327..26392 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0005" /evalue="1.00E-11" /label="NRPS-A_a8" /locus_tag="SSOG_RS38450" /protein_end="448" /protein_start="426" /score="36.7" /tool="antismash" /translation="YQGRADTQVKVRGFRIEPGEIE" aSDomain 26705..26902 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_PCP.1" /evalue="3.30E-24" /label="SSOG_RS38450_PCP.1" /locus_tag="SSOG_RS38450" /protein_end="618" /protein_start="552" /score="76.9" /tool="antismash" /translation="EETLAGIFTEVLGRARVGADDDFFALGGDSIQSIQLVSRARAQGV AVSSRQIFEHRTVASLARAAD" aSDomain 26978..27886 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_Epimerization.1" /evalue="2.40E-114" /label="SSOG_RS38450_Epimerization.1" /locus_tag="SSOG_RS38450" /protein_end="946" /protein_start="643" /score="374.6" /specificity="E activity: active" /specificity="Active site motif: HHMVVDG" /tool="antismash" /translation="PVARWIQETGPGFDSLLQAVVLELPPGIDRDGLAATLAAVVDRHD LLRATLRDDGLFVGPPGSVDVRPLIRDVACDGQWSGEPWRHLLVTELRALATRLDPAAG TVAQFVWFRPPSGPGRLLAGLHHMVVDGVSWRILMPDLAAAWKHVRAGTAPGLPAPVTS VRRWAHALTDEARAAGRVAELPRWTSIVDGPDPVLGTRRLDPAVDVQSTVEKVRVLLPA PATEALLTAVPAAFHGGVNDVLLAGLAMAVARWRRARGVDEPSTLLRLEGHGREEESVP GADLSRTVGWFTSVFPVRLDLG" CDS_motif 27035..27133 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0006" /evalue="1.90E-06" /label="C2_DCL_024-062" /locus_tag="SSOG_RS38450" /protein_end="695" /protein_start="662" /score="20.2" /tool="antismash" /translation="VVLELPPGIDRDGLAATLAAVVDRHDLLRATLR" CDS_motif 27347..27403 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0007" /evalue="1.10E-09" /label="NRPS-E2" /locus_tag="SSOG_RS38450" /protein_end="785" /protein_start="766" /score="30.6" /tool="antismash" /translation="GLHHMVVDGVSWRILMPDL" CDS_motif 27827..27877 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0008" /evalue="7.10E-09" /label="NRPS-E5" /locus_tag="SSOG_RS38450" /protein_end="943" /protein_start="926" /score="27.6" /tool="antismash" /translation="DLSRTVGWFTSVFPVRL" aSDomain 27926..28432 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_TIGR01720.1" /evalue="4.10E-35" /label="SSOG_RS38450_TIGR01720.1" /locus_tag="SSOG_RS38450" /protein_end="1128" /protein_start="959" /score="112.8" /tool="antismash" /translation="AGDAVKAVKEQLLAVPGKGLGYGLLRYLNPETAEVLRTRSMGQIG FNYLGRFSAADMPEELRGLGWTQTAELAEFTELAELDAGHDPAMPALSEVDINATVTDT PAGPRLGAVFGAPTGVLSPAEVRELAELWQRALEALVRHTGRPGAGGLTPSDVPLVSVA QDELTA" CDS_motif 27947..28009 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0009" /evalue="2.10E-10" /label="NRPS-E6" /locus_tag="SSOG_RS38450" /protein_end="987" /protein_start="966" /score="32.7" /tool="antismash" /translation="VKEQLLAVPGKGLGYGLLRYL" aSDomain 28460..29329 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="5.60E-90" /label="SSOG_RS38450_Condensation_DCL.1" /locus_tag="SSOG_RS38450" /protein_end="1427" /protein_start="1137" /score="293.4" /specificity="C activity: active" /specificity="Active site motif: HHVLFDG" /tool="antismash" /translation="DVWPLTPLQAGMLHHAQLAGADTYQVQLLFGFDGPVDARRMRAAG QALLDRHPSLRTAYLPDAAGDTVQLVVSDVALPWRERALPEAEFERFLAEDRAVPFDTA TPPLLRMTLVRVGADRTELLLTAHHVLFDGWSEPLLLRDLLWLYADPAALPEAPSFRDF LGVLAHRDRERSVRAHTDALDGIAGPTLLVPDRPDTDVDHDAVGSGFGEVELPVTADEA RALALRAAETGTTLNTVLQASWAVVLAELTGSPDVLFGTTVSGRPPALAGVDTTVGLFI NTLPVRARC" aSModule 28460..31174 /domains="nrpspksdomains_SSOG_RS38450_Condensation_DCL.1" /domains="nrpspksdomains_SSOG_RS38450_PCP.2" /incomplete /locus_tags="SSOG_RS38450" /tool="antismash" /type="nrps" CDS_motif 28469..28504 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0010" /evalue="4.20E-03" /label="C1_dual_004-017" /locus_tag="SSOG_RS38450" /protein_end="1152" /protein_start="1140" /score="10.2" /tool="antismash" /translation="PLTPLQAGMLHH" CDS_motif 28523..28639 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0011" /evalue="2.00E-14" /label="C2_DCL_024-062" /locus_tag="SSOG_RS38450" /protein_end="1197" /protein_start="1158" /score="45.8" /tool="antismash" /translation="DTYQVQLLFGFDGPVDARRMRAAGQALLDRHPSLRTAYL" CDS_motif 28841..28903 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0012" /evalue="1.90E-07" /label="C3_DCL_135-156" /locus_tag="SSOG_RS38450" /protein_end="1285" /protein_start="1264" /score="23.6" /tool="antismash" /translation="HHVLFDGWSEPLLLRDLLWLY" CDS_motif 29225..29320 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0013" /evalue="2.00E-18" /label="C5_DCL_263-294" /locus_tag="SSOG_RS38450" /protein_end="1424" /protein_start="1392" /score="58.8" /tool="antismash" /translation="DVLFGTTVSGRPPALAGVDTTVGLFINTLPVR" CDS_motif 29369..29482 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0014" /evalue="4.40E-13" /label="C67_DCL_14fromHMM" /locus_tag="SSOG_RS38450" /protein_end="1478" /protein_start="1440" /score="41.6" /tool="antismash" /translation="QAAQAALLEHHDCGLTEIHEATGFGALFDTLVVFQSYP" CDS_motif 29984..30025 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0015" /evalue="9.80E-03" /label="NRPS-A_a2" /locus_tag="SSOG_RS38450" /protein_end="1659" /protein_start="1645" /score="9.7" /tool="antismash" /translation="LAVMRAGGCALPMD" CDS_motif 30221..30265 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38450_0016" /evalue="4.00E+00" /label="NRPS-A_a3" /locus_tag="SSOG_RS38450" /protein_end="1739" /protein_start="1724" /score="1.3" /tool="antismash" /translation="CTADAAGRPYGVVVT" aSDomain 30980..31174 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38450_PCP.2" /evalue="1.30E-25" /label="SSOG_RS38450_PCP.2" /locus_tag="SSOG_RS38450" /protein_end="2042" /protein_start="1977" /score="81.4" /tool="antismash" /translation="EETLTRLFTEVLGRERIGVDDDFFALGGNSLLATRLIGRIRHELA VEVSIRSVFQHATIAELAAH" cand_cluster 31197..72495 /SMILES="NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC1=CNc2c1cccc2)C( =O)O" /candidate_cluster_number="4" /contig_edge="False" /detection_rules="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /kind="single" /product="NRP-metallophore" /protoclusters="3" /tool="antismash" protocluster 31197..72495 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="False" /core_location="[51196:52495](+)" /cutoff="30000" /detection_rule="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /neighbourhood="20000" /product="NRP-metallophore" /protocluster_number="3" /tool="antismash" proto_core 51197..52495 /aStool="rule-based-clusters" /tool="antismash" /cutoff="30000" /detection_rule="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /neighbourhood="20000" /product="NRP-metallophore" /protocluster_number="3" gene 31241..32020 /locus_tag="SSOG_RS38455" /old_locus_tag="SSOG_07628" CDS 31241..32020 /NRPS_PKS="Domain: Thioesterase (25-248). E-value: 5.8e-47. Score: 153.0. Matches aSDomain: nrpspksdomains_SSOG_RS38455_Thioesterase.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Thioesterase" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004: thioesterase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF013166.4" /locus_tag="SSOG_RS38455" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07628" /product="alpha/beta fold hydrolase" /protein_id="WP_009719712.1" /sec_met_domain="Thioesterase (E-value: 4.4e-46, bitscore: 157.0, seeds: 16, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 5.8e-08, bitscore: 32.7, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MSVLSTELVAETPYVWRARKPGSRHRLICFPHAGAGATTYADWAP LLPPEIELVAVQLPGRQNRIAEKPFTDVAPLVGVVAQALRPVLGGSFSFFGHSCGAALA FELAKTLRTKGLPGPARLFLSAQPAPGATGVRHLHDLPEDAFRAEMIGLGGIDEEIARD EFVMDSLLPVLRADFRLWERHRTAQDPPLDCPITVLAGDGDPRAPKETVDGWRNQTNAE FGTVFYPGGHFYFLDSPGDVIALIAEQTLGAPERRPA" aSDomain 31316..31984 /ASF="active site serine inconclusive" /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38455_Thioesterase.1" /evalue="5.80E-47" /label="SSOG_RS38455_Thioesterase.1" /locus_tag="SSOG_RS38455" /protein_end="248" /protein_start="25" /score="153.0" /tool="antismash" /translation="RLICFPHAGAGATTYADWAPLLPPEIELVAVQLPGRQNRIAEKPF TDVAPLVGVVAQALRPVLGGSFSFFGHSCGAALAFELAKTLRTKGLPGPARLFLSAQPA PGATGVRHLHDLPEDAFRAEMIGLGGIDEEIARDEFVMDSLLPVLRADFRLWERHRTAQ DPPLDCPITVLAGDGDPRAPKETVDGWRNQTNAEFGTVFYPGGHFYFLDSPGDVIALIA E" CDS_motif 31472..31573 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38455_0001" /evalue="1.50E-05" /label="NRPS-te1" /locus_tag="SSOG_RS38455" /protein_end="111" /protein_start="77" /score="17.6" /tool="antismash" /translation="GVVAQALRPVLGGSFSFFGHSCGAALAFELAKTL" gene <32705..>35161 /locus_tag="SSOG_RS38460" /old_locus_tag="SSOG_07629" /pseudo="" CDS 32705..>35161 /NRPS_PKS="Domain: CAL_domain (78-313). E-value: 3e-56. Score: 182.0. Matches aSDomain: nrpspksdomains_SSOG_RS38460_CAL_domain.1" /NRPS_PKS="Domain: PKS_KR (636-819). E-value: 9.4e-31. Score: 99.1. Matches aSDomain: nrpspksdomains_SSOG_RS38460_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012711.4" /locus_tag="SSOG_RS38460" /note="incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07629" /product="SDR family NAD(P)-dependent oxidoreductase" /pseudo="" /sec_met_domain="AMP-binding (E-value: 1.4e-65, bitscore: 220.6, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="adh_short (E-value: 2e-30, bitscore: 105.2, seeds: 230, tool: rule-based-clusters)" /transl_table=11 /translation="MPVLNLLTSGSTGVPKCVHHTHASIVARSLSVARHCGLTGDDVSL IWMPFDHVTVAMYNVRDVFVRCLHINAKIEHSLGDPLLWLDWVDRYRATNLWAPNFVFA MVNECADEIRTKGSWDLSCLREITNAGEPVIASTSHRFLELLAPHGLAADAMRPVWGMS ETCSGVTYAAQHLHDRTAGTVAIDPSSLGGTIRHLDPGDPRAVVLSTVGRPIPGVRLRV VDDTGRVLPEGRMGELRIRGLTMMHGYFANEEANRAAYDEDGWFRTGDLAFVHHGEIVI AGRKKDQIIVRGVNYMAHEIESVVEQVEGVRVTFTAAAGLREPGDDSDRLVVFFVPLRW DPEVLDGVTDAIRATLAREAGIAPDLLVPVTEAEFPKTGSGKIQRGALLDGLRAGAFAG RTIGAAPDEGEDPWVFRRQWTEIPAAPDAPDAAGTGVRLVIAEEEDRARLRVDGPLVAV DRGGEPTRRAPGHYAARTHDRGELRRMLAAVTADHGPIGTVVLAPPLSGGADPRARLAA ATAELSALVGALADGEFGHPLLLLVTAGAQYVRDGDTVDLGTCALPALVRTAAAENPRL VIRQLDLPAEADAWPAALSAELADRDRTGVVAVRDGRRRQPRLAPVERDGADPAPPLLA GGLYLVTGGLGGIGHDIAGYLTAAYGARLLLVGRSPADGEKAARLAELTALGEVVYRQL DVTDAAALEAAVTDAETRWGRPLDGALHLAGADPTGQWADLERHTVANESGEVFAAQYG AKVAGTLAVAEVLATRPDASLVLFGSVNGEFGGHSFGAYSAANGFLAGFADHWHHERRR AVHCLAW" CDS_motif 32720..32770 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0001" /evalue="6.50E-05" /label="NRPS-A_a3" /locus_tag="SSOG_RS38460" /protein_end="22" /protein_start="5" /score="15.8" /tool="antismash" /translation="LLTSGSTGVPKCVHHTH" aSDomain 32939..33643 /aSDomain="CAL_domain" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38460_CAL_domain.1" /evalue="3.00E-56" /label="SSOG_RS38460_CAL_domain.1" /locus_tag="SSOG_RS38460" /protein_end="313" /protein_start="78" /score="182.0" /specificity="Minowa: Acetyl-CoA" /tool="antismash" /translation="GDPLLWLDWVDRYRATNLWAPNFVFAMVNECADEIRTKGSWDLSC LREITNAGEPVIASTSHRFLELLAPHGLAADAMRPVWGMSETCSGVTYAAQHLHDRTAG TVAIDPSSLGGTIRHLDPGDPRAVVLSTVGRPIPGVRLRVVDDTGRVLPEGRMGELRIR GLTMMHGYFANEEANRAAYDEDGWFRTGDLAFVHHGEIVIAGRKKDQIIVRGVNYMAHE IESVVEQVEGVRV" aSModule 32939..>35161 /domains="nrpspksdomains_SSOG_RS38460_CAL_domain.1" /domains="nrpspksdomains_SSOG_RS38460_PKS_KR.1" /incomplete /locus_tags="SSOG_RS38460" /starter_module /tool="antismash" /type="pks" CDS_motif 33395..33478 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0002" /evalue="2.90E-03" /label="NRPS-A_a6" /locus_tag="SSOG_RS38460" /protein_end="258" /protein_start="230" /score="10.1" /tool="antismash" /translation="PEGRMGELRIRGLTMMHGYFANEEANRA" CDS_motif 33548..33610 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0003" /evalue="5.60E-05" /label="NRPS-A_a8" /locus_tag="SSOG_RS38460" /protein_end="302" /protein_start="281" /score="15.8" /tool="antismash" /translation="AGRKKDQIIVRGVNYMAHEIE" aSDomain 34613..>35161 /ASF="KR domain putatively catalyzing L-configuration product formation" /ASF="catalytic triad S,Y,N inconclusive" /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38460_PKS_KR.1" /evalue="9.40E-31" /label="SSOG_RS38460_PKS_KR.1" /locus_tag="SSOG_RS38460" /protein_end="819" /protein_start="636" /score="99.1" /specificity="KR activity: active" /specificity="KR stereochemistry: (unknown)" /tool="antismash" /translation="GLYLVTGGLGGIGHDIAGYLTAAYGARLLLVGRSPADGEKAARLA ELTALGEVVYRQLDVTDAAALEAAVTDAETRWGRPLDGALHLAGADPTGQWADLERHTV ANESGEVFAAQYGAKVAGTLAVAEVLATRPDASLVLFGSVNGEFGGHSFGAYSAANGFL AGFADHWHHERRRAVHCLAW" CDS_motif 34619..34714 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0004" /evalue="9.00E-08" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38460" /protein_end="670" /protein_start="638" /score="24.8" /tool="antismash" /translation="YLVTGGLGGIGHDIAGYLTAAYGARLLLVGRS" CDS_motif 34982..35038 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0005" /evalue="5.40E+00" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38460" /protein_end="778" /protein_start="759" /score="-0.2" /tool="antismash" /translation="LAVAEVLATRPDASLVLFG" CDS_motif 35027..35125 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38460_0006" /evalue="1.70E-08" /label="PKSI-KR_m4" /locus_tag="SSOG_RS38460" /protein_end="807" /protein_start="774" /score="27.0" /tool="antismash" /translation="VLFGSVNGEFGGHSFGAYSAANGFLAGFADHWH" gene 35330..35803 /locus_tag="SSOG_RS57655" CDS 35330..35803 /NRPS_PKS="Domain: PCP (85-154). E-value: 5.9e-23. Score: 72.9. Matches aSDomain: nrpspksdomains_SSOG_RS57655_PCP.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012759.4" /locus_tag="SSOG_RS57655" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="phosphopantetheine-binding protein" /protein_id="WP_281048209.1" /sec_met_domain="PP-binding (E-value: 1.2e-14, bitscore: 53.7, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MDELVPEQLRTGEVLVAYTADDIDPETVRAAVAPSTRDRPVPVRL VRVDHLPRDAAGRVDTARLLAETAVGKPGRRTVTPPADDLERRVAALWSEALNCPEVGR DDSFFDLGGNSVRATRLLALVDDAFAVRVPTQRLYENPTVQAMAAVVAEATAP" aSDomain 35585..35791 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS57655_PCP.1" /evalue="5.90E-23" /label="SSOG_RS57655_PCP.1" /locus_tag="SSOG_RS57655" /protein_end="154" /protein_start="85" /score="72.9" /tool="antismash" /translation="ERRVAALWSEALNCPEVGRDDSFFDLGGNSVRATRLLALVDDAFA VRVPTQRLYENPTVQAMAAVVAEA" gene 36101..41101 /locus_tag="SSOG_RS47205" /old_locus_tag="SSOG_07630" CDS 36101..41101 /NRPS_PKS="Domain: Condensation_LCL (1-301). E-value: 1.6e-108. Score: 354.2. Matches aSDomain: nrpspksdomains_SSOG_RS47205_Condensation_LCL.1" /NRPS_PKS="Domain: AMP-binding (464-855). E-value: 2.6e-96. Score: 314.6. Matches aSDomain: nrpspksdomains_SSOG_RS47205_AMP-binding.1" /NRPS_PKS="Domain: PCP (976-1043). E-value: 1.1e-24. Score: 78.4. Matches aSDomain: nrpspksdomains_SSOG_RS47205_PCP.1" /NRPS_PKS="Domain: Epimerization (1063-1358). E-value: 1.4e-115. Score: 378.7. Matches aSDomain: nrpspksdomains_SSOG_RS47205_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (1372-1534). E-value: 2.3e-38. Score: 123.4. Matches aSDomain: nrpspksdomains_SSOG_RS47205_TIGR01720.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127: condensation domain-containing protein" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:NF012873.4" /locus_tag="SSOG_RS47205" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07630" /product="non-ribosomal peptide synthetase" /protein_id="WP_050800097.1" /sec_met_domain="Condensation (E-value: 4.6e-65, bitscore: 218.7, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 7.1e-106, bitscore: 353.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 7.9e-12, bitscore: 44.6, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MIPLSFAQRRLWFIDRFEGPSATYNIPFVLRLDGALDTAALSSAL RDVVIRHESLHTLFVEDADGMPVQQVRPADEVLMDVPVVDVASEGIDGLVMEAAAHRFD LSTEIPVRATLLRGGPSEHVLVLVVHHAAADGESMVPLSRDLATAYAARLRGEAPGWPE LAVQYGDYTLWQRELLGESDDPGSLLSTQLAYWRDELAGAPQQLRLPTDRPRPSEAGHR GDAVVFTVDRELVAAVQELARSRGLTLAMAMQSALAVLLHHLGGGEDVTIGSTIAGRTD EALNDLVGFFVNTWVLRTDLSGNPTLEQVLDHVQDKALSAYDHQAVPFERLVEALNPER STAYHPFFQVMFSWQSEARIDLDLPGLTATLEAVPTGTAKFDLEFNFAAVEDGVRCTLE YATDLFDRSTAAAAGERFVRVLRHLVAEPGARIGAIDVLSRAERELLSGRNETAAQLPG VTVPQLFAQQAARTPDAVAVTSGTRELTYRDLDERADRLARELVRRGIGPESLVGLALP RSADLVTAMLGILKSGAAYLPVDPRYPSARLGLILSEARPGLILTDAETEAVLPEGGAP RLLLGDVDLEHGTADAPAVALRPDHAAYVMYTSGSTGTPKGVVITHRGVVNGVTQLASA IGLAPGSRMLAGTSVNFDVSVFEIVTTLTTGGTVEIARDVLVLGERDGWSGSVISTVPS VFAELVDGIADRTDVECVVFAGEALPASLVRRVRDAFPGVRVVNAYGQSESFYATTYTA PDGATPDGSGSAPIGAPLGNMRTYVLGPGLTPVPPGVVGELYVAGEVGRGYHERPGLTA GRFVADPFGNPGDRMYRTGDLARWNSEGQLEFAGRDDAQMKVRGFRIEAGEVEAALTAH SGVAQAVVTTYDRPGGKQLVGYVVSTGASGGSVENLGELEVDLTAGVSAAELRAFVSER LPEFMVPSAFVMLDRLPLAPNGKLDHAALPAPEFTGGDYRAPRTAAEKILAGVFSEVLG LERVGVDDDFFAVGGDSIRSIQVVSRARARGMDVSPRQIFQSRTVAELAAVVGAGADGD AGGVLAELEGGGEGWMPLLPVSEFVLGLGGGVGRFAMSAVVDVPAEVDEAGLVAVLGAV VDRHDVLRSRLVPGGLVVGPRGSVDVAGLVRCVASGGDVQRELDDAAGLLDPAAGVMAR FVWLMDERQLLVVLHHLVVDGVSWRVLLPDLAEAWRLIRQGEVAELAAPVTSVRRWAHA LVEEAGRRERVAELGVWRSVVEGPDPLLGSRALDPAVDVQSALDSLWVRLPETVTHALL SDIPGAFRGGVNDGLLTGLALAVARWRRARGVEESSSLVRLEGHGREEGVVPGADLSRT VGWFTSVFPVRLDVAGVDVEEAFAGGPAAGVAVKAVKEQLLSIPDKGLGYGLLRYLNEE TGAELAPYSTGQIAFNYLGRFSSSDMPEHLRGLGWTRSPGTEGLMPRLDDDMPAMAALD INAYVTEGERGPRLTARFGFAPGVLSPEDVQELADLWCAALEGLAGHASRPDAGGLTPS DVPLVPVRQSEIDGWEERYPGLRDVWPLTDLQSGLLFHALLAGTTFDAYHMQMVYHLAG RVDPDRLHAAGQALLDRHANLRTAFVANTTGERVPFVIDGVQLPWRHLDLTTADAPERD RHSGRFLEERARTRTDHFRTRPGLRCCA" aSDomain 36104..37003 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47205_Condensation_LCL.1" /domain_subtypes="Condensation_LCL" /evalue="1.60E-108" /label="SSOG_RS47205_Condensation_LCL.1" /locus_tag="SSOG_RS47205" /protein_end="301" /protein_start="1" /score="354.2" /specificity="C activity: active" /specificity="Active site motif: HHAAADG" /tool="antismash" /translation="IPLSFAQRRLWFIDRFEGPSATYNIPFVLRLDGALDTAALSSALR DVVIRHESLHTLFVEDADGMPVQQVRPADEVLMDVPVVDVASEGIDGLVMEAAAHRFDL STEIPVRATLLRGGPSEHVLVLVVHHAAADGESMVPLSRDLATAYAARLRGEAPGWPEL AVQYGDYTLWQRELLGESDDPGSLLSTQLAYWRDELAGAPQQLRLPTDRPRPSEAGHRG DAVVFTVDRELVAAVQELARSRGLTLAMAMQSALAVLLHHLGGGEDVTIGSTIAGRTDE ALNDLVGFFVNTWVLRTDL" aSModule 36104..40702 /complete /domains="nrpspksdomains_SSOG_RS47205_Condensation_LCL.1" /domains="nrpspksdomains_SSOG_RS47205_AMP-binding.1" /domains="nrpspksdomains_SSOG_RS47205_PCP.1" /domains="nrpspksdomains_SSOG_RS47205_Epimerization.1" /domains="nrpspksdomains_SSOG_RS47205_TIGR01720.1" /locus_tags="SSOG_RS47205" /monomer_pairings="Leu -> D-Leu" /tool="antismash" /type="nrps" CDS_motif 36164..36280 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0001" /evalue="1.10E-16" /label="C2_LCL_024-062" /locus_tag="SSOG_RS47205" /protein_end="60" /protein_start="21" /score="53.1" /tool="antismash" /translation="ATYNIPFVLRLDGALDTAALSSALRDVVIRHESLHTLFV" CDS_motif 36485..36550 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0002" /evalue="2.90E-06" /label="C3_LCL_132-143" /locus_tag="SSOG_RS47205" /protein_end="150" /protein_start="128" /score="19.9" /tool="antismash" /translation="VHHAAADGESMVPLSRDLATAY" CDS_motif 36599..36637 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0003" /evalue="6.40E-05" /label="C4_LCL_164-176" /locus_tag="SSOG_RS47205" /protein_end="179" /protein_start="166" /score="15.5" /tool="antismash" /translation="QYGDYTLWQRELL" CDS_motif 36905..36994 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0004" /evalue="6.00E-14" /label="C5_LCL_267-296" /locus_tag="SSOG_RS47205" /protein_end="298" /protein_start="268" /score="44.3" /tool="antismash" /translation="DVTIGSTIAGRTDEALNDLVGFFVNTWVLR" CDS_motif 37043..37162 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0005" /evalue="7.60E-23" /label="C67_LCL_14fromHMM" /locus_tag="SSOG_RS47205" /protein_end="354" /protein_start="314" /score="73.0" /tool="antismash" /translation="QDKALSAYDHQAVPFERLVEALNPERSTAYHPFFQVMFSW" aSDomain 37493..38665 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47205_AMP-binding.1" /evalue="2.60E-96" /label="SSOG_RS47205_AMP-binding.1" /locus_tag="SSOG_RS47205" /protein_end="855" /protein_start="464" /score="314.6" /specificity="substrate consensus: Leu" /tool="antismash" /translation="FAQQAARTPDAVAVTSGTRELTYRDLDERADRLARELVRRGIGPE SLVGLALPRSADLVTAMLGILKSGAAYLPVDPRYPSARLGLILSEARPGLILTDAETEA VLPEGGAPRLLLGDVDLEHGTADAPAVALRPDHAAYVMYTSGSTGTPKGVVITHRGVVN GVTQLASAIGLAPGSRMLAGTSVNFDVSVFEIVTTLTTGGTVEIARDVLVLGERDGWSG SVISTVPSVFAELVDGIADRTDVECVVFAGEALPASLVRRVRDAFPGVRVVNAYGQSES FYATTYTAPDGATPDGSGSAPIGAPLGNMRTYVLGPGLTPVPPGVVGELYVAGEVGRGY HERPGLTAGRFVADPFGNPGDRMYRTGDLARWNSEGQLEFAGRDDAQMKVR" CDS_motif 37679..37720 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0006" /evalue="1.10E-04" /label="NRPS-A_a2" /locus_tag="SSOG_RS47205" /protein_end="540" /protein_start="526" /score="15.5" /tool="antismash" /translation="LGILKSGAAYLPVD" CDS_motif 37907..37966 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0007" /evalue="1.80E-10" /label="NRPS-A_a3" /locus_tag="SSOG_RS47205" /protein_end="622" /protein_start="602" /score="32.6" /tool="antismash" /translation="AYVMYTSGSTGTPKGVVITH" CDS_motif 38459..38545 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0008" /evalue="1.70E-11" /label="NRPS-A_a6" /locus_tag="SSOG_RS47205" /protein_end="815" /protein_start="786" /score="36.3" /tool="antismash" /translation="PPGVVGELYVAGEVGRGYHERPGLTAGRF" CDS_motif 38630..38695 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0009" /evalue="2.80E-08" /label="NRPS-A_a8" /locus_tag="SSOG_RS47205" /protein_end="865" /protein_start="843" /score="26.1" /tool="antismash" /translation="FAGRDDAQMKVRGFRIEAGEVE" aSDomain 39029..39229 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47205_PCP.1" /evalue="1.10E-24" /label="SSOG_RS47205_PCP.1" /locus_tag="SSOG_RS47205" /protein_end="1043" /protein_start="976" /score="78.4" /tool="antismash" /translation="EKILAGVFSEVLGLERVGVDDDFFAVGGDSIRSIQVVSRARARGM DVSPRQIFQSRTVAELAAVVGA" aSDomain 39290..40174 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47205_Epimerization.1" /evalue="1.40E-115" /label="SSOG_RS47205_Epimerization.1" /locus_tag="SSOG_RS47205" /protein_end="1358" /protein_start="1063" /score="378.7" /specificity="E activity: active" /specificity="Active site motif: HHLVVDG" /tool="antismash" /translation="MPLLPVSEFVLGLGGGVGRFAMSAVVDVPAEVDEAGLVAVLGAVV DRHDVLRSRLVPGGLVVGPRGSVDVAGLVRCVASGGDVQRELDDAAGLLDPAAGVMARF VWLMDERQLLVVLHHLVVDGVSWRVLLPDLAEAWRLIRQGEVAELAAPVTSVRRWAHAL VEEAGRRERVAELGVWRSVVEGPDPLLGSRALDPAVDVQSALDSLWVRLPETVTHALLS DIPGAFRGGVNDGLLTGLALAVARWRRARGVEESSSLVRLEGHGREEGVVPGADLSRTV GWFTSVFPVRLDVA" CDS_motif 39353..39454 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0010" /evalue="9.00E-06" /label="C2_LCL_024-062" /locus_tag="SSOG_RS47205" /protein_end="1118" /protein_start="1084" /score="18.1" /tool="antismash" /translation="MSAVVDVPAEVDEAGLVAVLGAVVDRHDVLRSRL" CDS_motif 39626..39691 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0011" /evalue="1.70E-10" /label="NRPS-E2" /locus_tag="SSOG_RS47205" /protein_end="1197" /protein_start="1175" /score="33.1" /tool="antismash" /translation="LLVVLHHLVVDGVSWRVLLPDL" misc_feature 39854..39856 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" CDS_motif 40115..40165 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0012" /evalue="5.60E-09" /label="NRPS-E5" /locus_tag="SSOG_RS47205" /protein_end="1355" /protein_start="1338" /score="27.9" /tool="antismash" /translation="DLSRTVGWFTSVFPVRL" aSDomain 40217..40702 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47205_TIGR01720.1" /evalue="2.30E-38" /label="SSOG_RS47205_TIGR01720.1" /locus_tag="SSOG_RS47205" /protein_end="1534" /protein_start="1372" /score="123.4" /tool="antismash" /translation="GVAVKAVKEQLLSIPDKGLGYGLLRYLNEETGAELAPYSTGQIAF NYLGRFSSSDMPEHLRGLGWTRSPGTEGLMPRLDDDMPAMAALDINAYVTEGERGPRLT ARFGFAPGVLSPEDVQELADLWCAALEGLAGHASRPDAGGLTPSDVPLVPVRQSEIDG" CDS_motif 40235..40297 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0013" /evalue="7.30E-11" /label="NRPS-E6" /locus_tag="SSOG_RS47205" /protein_end="1399" /protein_start="1378" /score="34.2" /tool="antismash" /translation="VKEQLLSIPDKGLGYGLLRYL" CDS_motif 40799..40915 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS47205_0014" /evalue="7.30E-18" /label="C2_DCL_024-062" /locus_tag="SSOG_RS47205" /protein_end="1605" /protein_start="1566" /score="56.9" /tool="antismash" /translation="DAYHMQMVYHLAGRVDPDRLHAAGQALLDRHANLRTAFV" gene 41098..>41220 /locus_tag="SSOG_RS57660" /pseudo="" CDS 41098..>41220 /GO_function="GO:0003824 - catalytic activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Condensation" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012873.4" /locus_tag="SSOG_RS57660" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /product="condensation domain-containing protein" /pseudo="" /sec_met_domain="Condensation (E-value: 1.3e-08, bitscore: 33.3, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="MTLLTTAPRRSELVLTAHHVLIDGWSVPLLMRDLLRLYGAG" gene 41527..>43554 /locus_tag="SSOG_RS38465" /old_locus_tag="SSOG_07631" CDS 41527..>43554 /NRPS_PKS="Domain: AMP-binding (197-586). E-value: 3.7e-109. Score: 357.0. Matches aSDomain: nrpspksdomains_SSOG_RS38465_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:TIGR01733.1" /locus_tag="SSOG_RS38465" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07631" /product="amino acid adenylation domain-containing protein" /protein_id="WP_167542534.1" /sec_met_domain="Condensation (E-value: 1.4e-08, bitscore: 33.3, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 7.5e-118, bitscore: 392.8, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MVFGTTVSGRPPAVPGVDEMVGMFINTLPVRADCAPGATVADLLT GLQERQAVLLDHHHYGLADIQQAIGLPSLFDTAVVFESYPVDRAGISAAHDEAEVAITG ITPFTGSHYPLVVTADADPHLRVALQYHHHVFDHETVTGFAARFERVLRQLAEDPGLLV GQVDVLDPAERQQWRAEWHAATRPVPAVSFPELVRAQAAARPDAIAVEDDRQWLGYGEL ERRANQLAHHLRGLGAGPERVVGLCVERGADLIVGLLGIMKAGAAYVPLDPGYPADRLA FMLRDSGAGLVVAEPGTRSALGATDAVVVDLAEDADRIRQQPVTVPEDGPRVTDLAYVI YTSGSTGRPKGVLVTHEGIANLAADMADRLRITPDSRVLQFASASFDGAVMEVLMALPN GATLVLPPHGPVIGEALHGFLRERRITHTLLVPSLVATLDPEGLDTLRTLVVGAEAASG DLVARWSADRLVVNAYGPTETTIVATLSEPLSGSAVPPIGSPVANTRVHLLDHALRPVP PGVAGDLYIAGPHLARGYHGRTALTAERFTADPYGELGSRMYRSGDVARRRGDGTLEYI GRADDQVKIRGFRIEPGEIEGVLGGHPKVAQAVVTVRDTGSGGRLLVAYVVPAADDTGR LTAELREHAEAGLPAHMVPSAFVLLDRLPTTASGKLDRAAL" CDS_motif 41530..41619 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0001" /evalue="9.70E-19" /label="C5_DCL_263-294" /locus_tag="SSOG_RS38465" /protein_end="31" /protein_start="1" /score="59.8" /tool="antismash" /translation="VFGTTVSGRPPAVPGVDEMVGMFINTLPVR" CDS_motif 41668..41781 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0002" /evalue="6.20E-15" /label="C67_DCL_14fromHMM" /locus_tag="SSOG_RS38465" /protein_end="85" /protein_start="47" /score="47.6" /tool="antismash" /translation="QERQAVLLDHHHYGLADIQQAIGLPSLFDTAVVFESYP" aSDomain 42118..43284 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38465_AMP-binding.1" /evalue="3.70E-109" /label="SSOG_RS38465_AMP-binding.1" /locus_tag="SSOG_RS38465" /protein_end="586" /protein_start="197" /score="357.0" /specificity="substrate consensus: Thr" /tool="antismash" /translation="RAQAAARPDAIAVEDDRQWLGYGELERRANQLAHHLRGLGAGPER VVGLCVERGADLIVGLLGIMKAGAAYVPLDPGYPADRLAFMLRDSGAGLVVAEPGTRSA LGATDAVVVDLAEDADRIRQQPVTVPEDGPRVTDLAYVIYTSGSTGRPKGVLVTHEGIA NLAADMADRLRITPDSRVLQFASASFDGAVMEVLMALPNGATLVLPPHGPVIGEALHGF LRERRITHTLLVPSLVATLDPEGLDTLRTLVVGAEAASGDLVARWSADRLVVNAYGPTE TTIVATLSEPLSGSAVPPIGSPVANTRVHLLDHALRPVPPGVAGDLYIAGPHLARGYHG RTALTAERFTADPYGELGSRMYRSGDVARRRGDGTLEYIGRADDQVKIR" CDS_motif 42301..42342 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0003" /evalue="1.40E-06" /label="NRPS-A_a2" /locus_tag="SSOG_RS38465" /protein_end="272" /protein_start="258" /score="21.2" /tool="antismash" /translation="LGIMKAGAAYVPLD" CDS_motif 42535..42594 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0004" /evalue="3.10E-11" /label="NRPS-A_a3" /locus_tag="SSOG_RS38465" /protein_end="356" /protein_start="336" /score="34.9" /tool="antismash" /translation="AYVIYTSGSTGRPKGVLVTH" CDS_motif 43075..43164 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0005" /evalue="1.30E-15" /label="NRPS-A_a6" /locus_tag="SSOG_RS38465" /protein_end="546" /protein_start="516" /score="49.4" /tool="antismash" /translation="PPGVAGDLYIAGPHLARGYHGRTALTAERF" CDS_motif 43249..43314 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0006" /evalue="1.60E-13" /label="NRPS-A_a8" /locus_tag="SSOG_RS38465" /protein_end="596" /protein_start="574" /score="42.3" /tool="antismash" /translation="YIGRADDQVKIRGFRIEPGEIE" CDS_motif 43396..43431 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38465_0007" /evalue="2.30E+01" /label="NRPS-A_a3" /locus_tag="SSOG_RS38465" /protein_end="635" /protein_start="623" /score="-1.1" /tool="antismash" /translation="AYVVPAADDTGR" gap 43555..45769 /estimated_length=2215 gene complement(<45770..46029) /locus_tag="SSOG_RS56800" CDS complement(<45770..46029) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS56800" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /product="hypothetical protein" /protein_id="WP_245606704.1" /transl_table=11 /translation="MPIHDRTQHGHQTRLIHARRDVHHRRHRKPAHTATKAQHELRDRQ QRHPPLTTTLQLRQRPARIPASTHHRGQPRHRAALEDLPGA" gene 45949..>49935 /locus_tag="SSOG_RS54335" /old_locus_tag="SSOG_07632" CDS 45949..>49935 /NRPS_PKS="Domain: Epimerization (1-274). E-value: 2.6e-115. Score: 377.8. Matches aSDomain: nrpspksdomains_SSOG_RS54335_Epimerization.1" /NRPS_PKS="Domain: TIGR01720 (288-450). E-value: 8.7e-39. Score: 124.8. Matches aSDomain: nrpspksdomains_SSOG_RS54335_TIGR01720.1" /NRPS_PKS="Domain: Condensation_DCL (459-756). E-value: 1e-106. Score: 348.4. Matches aSDomain: nrpspksdomains_SSOG_RS54335_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (918-1309). E-value: 5.2e-108. Score: 353.2. Matches aSDomain: nrpspksdomains_SSOG_RS54335_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127: condensation domain-containing protein" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:NF012873.4" /locus_tag="SSOG_RS54335" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07632" /product="amino acid adenylation domain-containing protein" /protein_id="WP_245606671.1" /sec_met_domain="Condensation (E-value: 3.7e-66, bitscore: 222.3, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 4.9e-111, bitscore: 370.3, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MSAVVDVPAGVDETGLVAVLGAVVDRHDVLRSRLVPGGLVVGPRG SVDVAGLVRCVASGGDVQEALDEAAGLLDPAAGVMARFVWLMDERQLLVVLHHLVVDGV SWRVLLPDLAEAWRLIRQGEVAELAAPVTSVRRWAHALVEEAGRRERVAELGVWRSVVE GPDPLLGSRALDPAVDVRSTVDTFSVRLPAQVTEALLTGIPAAFRSGVNDGLLAGLALA VARWRRARGVAESSSLVRLEGHGREEGVVPGADLSRTVGWFTSVFPVRLDVAGVDVEEA FAGGPAAGVAVKAVKEQLLAIPDKGLGYGLLRYLNQETGAELAPYSTGQIAFNYLGRFS SSDMPEHLRGLGWTPSPGTEGLMPRLDDDMPAMAVLDINAYVTDTPRGPELEARFDFPT GLLPEHEARELADLWCAALEGLATHASRPDTGGLTPSDVPLVPVRQSEIDGWEERYPGL RDVWPLTDLQSGLLFQSQLADGGHDAYHMQMVYHLAGRVDPDRLRAAGQALLDRHANLR TAFVANTTGERVQLVLDGVQLPWCHLDLTTADVPGRDQALRNFLDQDRAARFDPAQPPL LRMALVLTGEAEAELVLTAHHALFDGWSLPLLTQDLLRLYGSGGDPAVLPRVPGYRDFL AWLSRRDRAESARAWAAELDGMDEPTLLAPGAVAETGQGNVGHIDVPLADDVSQELSRR AAELGVTLNTVLQGAWGLVLAELTGRQDVVFGTTVSGRPPELADADAMVGLFINTLPVR VEVSPWDTLGSLLTGLQDRQAALLDHHHYGLAEIQRAVGLPALFDSVMVLESFPVDRAA IAEANSAAGISVTRVSSDGGTHYPLGVAATADPHLRVALQYQHALFGQGAAEDIAERFG RVLRQIAEDIDVPLGLVGTLPPAERERLLAEAGDTALPVPGGTIAEQFARQAAATPDAV AVHFEDVRLTYREVDTRANALAHELVRRQVGPGSVVAVSVRRSPDLVVALLAVLKAGGA YLPIDSTLPADRIAYMGTDSGARLALADATTEAALTGLPCPVLRVDGMDGALPDNARPV ASAARVDDLAYVIYTSGSTGRPKGVAVTHRGMASLVASHVERLHVTPDSRMLQLVSPSF DVSLCEVFTALLSGASLVLADAERLVPGPPLAETADRHGVTHLMLTPTMLAAMPDGSFG SVTCLVIGGEVAPPELVAAWSPGRRMVNVYGPTEITVCATMSLPLVEDGGARPIGRPIA NTRVYVLDGALRPVPAGVAGELYIAGPGLARAYVGRPDLTAARFVACPFGGSGERMYRT GDVVARTPDGDLVFLGRTDEQVKIRGFRIELGEIESALRAHPAVR" aSDomain 45952..46770 /aSDomain="Epimerization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS54335_Epimerization.1" /evalue="2.60E-115" /label="SSOG_RS54335_Epimerization.1" /locus_tag="SSOG_RS54335" /protein_end="274" /protein_start="1" /score="377.8" /specificity="E activity: active" /specificity="Active site motif: HHLVVDG" /tool="antismash" /translation="SAVVDVPAGVDETGLVAVLGAVVDRHDVLRSRLVPGGLVVGPRGS VDVAGLVRCVASGGDVQEALDEAAGLLDPAAGVMARFVWLMDERQLLVVLHHLVVDGVS WRVLLPDLAEAWRLIRQGEVAELAAPVTSVRRWAHALVEEAGRRERVAELGVWRSVVEG PDPLLGSRALDPAVDVRSTVDTFSVRLPAQVTEALLTGIPAAFRSGVNDGLLAGLALAV ARWRRARGVAESSSLVRLEGHGREEGVVPGADLSRTVGWFTSVFPVRLDVA" aSModule 45952..47298 /domains="nrpspksdomains_SSOG_RS54335_Epimerization.1" /domains="nrpspksdomains_SSOG_RS54335_TIGR01720.1" /incomplete /locus_tags="SSOG_RS54335" /tool="antismash" /type="unknown" CDS_motif 45979..46050 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0001" /evalue="6.50E-05" /label="C2_LCL_024-062" /locus_tag="SSOG_RS54335" /protein_end="34" /protein_start="10" /score="15.4" /tool="antismash" /translation="VDETGLVAVLGAVVDRHDVLRSRL" CDS_motif 46222..46287 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0002" /evalue="1.30E-10" /label="NRPS-E2" /locus_tag="SSOG_RS54335" /protein_end="113" /protein_start="91" /score="33.4" /tool="antismash" /translation="LLVVLHHLVVDGVSWRVLLPDL" CDS_motif 46711..46761 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0003" /evalue="4.40E-09" /label="NRPS-E5" /locus_tag="SSOG_RS54335" /protein_end="271" /protein_start="254" /score="28.3" /tool="antismash" /translation="DLSRTVGWFTSVFPVRL" aSDomain 46813..47298 /aSDomain="TIGR01720" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS54335_TIGR01720.1" /evalue="8.70E-39" /label="SSOG_RS54335_TIGR01720.1" /locus_tag="SSOG_RS54335" /protein_end="450" /protein_start="288" /score="124.8" /tool="antismash" /translation="GVAVKAVKEQLLAIPDKGLGYGLLRYLNQETGAELAPYSTGQIAF NYLGRFSSSDMPEHLRGLGWTPSPGTEGLMPRLDDDMPAMAVLDINAYVTDTPRGPELE ARFDFPTGLLPEHEARELADLWCAALEGLATHASRPDTGGLTPSDVPLVPVRQSEIDG" CDS_motif 46831..46893 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0004" /evalue="4.00E-11" /label="NRPS-E6" /locus_tag="SSOG_RS54335" /protein_end="315" /protein_start="294" /score="35.0" /tool="antismash" /translation="VKEQLLAIPDKGLGYGLLRYL" aSDomain 47326..48216 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS54335_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="1.00E-106" /label="SSOG_RS54335_Condensation_DCL.1" /locus_tag="SSOG_RS54335" /protein_end="756" /protein_start="459" /score="348.4" /specificity="C activity: active" /specificity="Active site motif: HHALFDG" /tool="antismash" /translation="DVWPLTDLQSGLLFQSQLADGGHDAYHMQMVYHLAGRVDPDRLRA AGQALLDRHANLRTAFVANTTGERVQLVLDGVQLPWCHLDLTTADVPGRDQALRNFLDQ DRAARFDPAQPPLLRMALVLTGEAEAELVLTAHHALFDGWSLPLLTQDLLRLYGSGGDP AVLPRVPGYRDFLAWLSRRDRAESARAWAAELDGMDEPTLLAPGAVAETGQGNVGHIDV PLADDVSQELSRRAAELGVTLNTVLQGAWGLVLAELTGRQDVVFGTTVSGRPPELADAD AMVGLFINTLPVRVEV" aSModule 47326..51074 /complete /domains="nrpspksdomains_SSOG_RS54335_Condensation_DCL.1" /domains="nrpspksdomains_SSOG_RS54335_AMP-binding.1" /domains="nrpspksdomains_SSOG_RS38475_PCP.1" /domains="nrpspksdomains_SSOG_RS38475_Thioesterase.1" /final_module /locus_tags="SSOG_RS38475" /locus_tags="SSOG_RS54335" /monomer_pairings="Trp -> Trp" /monomer_pairings="Trp -> Trp" /tool="antismash" /type="nrps" CDS_motif 47395..47511 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0005" /evalue="1.70E-18" /label="C2_DCL_024-062" /locus_tag="SSOG_RS54335" /protein_end="521" /protein_start="482" /score="58.9" /tool="antismash" /translation="DAYHMQMVYHLAGRVDPDRLRAAGQALLDRHANLRTAFV" CDS_motif 47734..47796 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0006" /evalue="1.50E-09" /label="C3_DCL_135-156" /locus_tag="SSOG_RS54335" /protein_end="616" /protein_start="595" /score="30.3" /tool="antismash" /translation="HHALFDGWSLPLLTQDLLRLY" CDS_motif 48112..48207 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0007" /evalue="7.00E-21" /label="C5_DCL_263-294" /locus_tag="SSOG_RS54335" /protein_end="753" /protein_start="721" /score="66.7" /tool="antismash" /translation="DVVFGTTVSGRPPELADADAMVGLFINTLPVR" CDS_motif 48256..48369 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0008" /evalue="6.70E-15" /label="C67_DCL_14fromHMM" /locus_tag="SSOG_RS54335" /protein_end="807" /protein_start="769" /score="47.4" /tool="antismash" /translation="QDRQAALLDHHHYGLAEIQRAVGLPALFDSVMVLESFP" aSDomain 48703..49875 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS54335_AMP-binding.1" /evalue="5.20E-108" /label="SSOG_RS54335_AMP-binding.1" /locus_tag="SSOG_RS54335" /protein_end="1309" /protein_start="918" /score="353.2" /specificity="substrate consensus: Trp" /tool="antismash" /translation="FARQAAATPDAVAVHFEDVRLTYREVDTRANALAHELVRRQVGPG SVVAVSVRRSPDLVVALLAVLKAGGAYLPIDSTLPADRIAYMGTDSGARLALADATTEA ALTGLPCPVLRVDGMDGALPDNARPVASAARVDDLAYVIYTSGSTGRPKGVAVTHRGMA SLVASHVERLHVTPDSRMLQLVSPSFDVSLCEVFTALLSGASLVLADAERLVPGPPLAE TADRHGVTHLMLTPTMLAAMPDGSFGSVTCLVIGGEVAPPELVAAWSPGRRMVNVYGPT EITVCATMSLPLVEDGGARPIGRPIANTRVYVLDGALRPVPAGVAGELYIAGPGLARAY VGRPDLTAARFVACPFGGSGERMYRTGDVVARTPDGDLVFLGRTDEQVKIR" CDS_motif 48889..48930 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0009" /evalue="1.10E-05" /label="NRPS-A_a2" /locus_tag="SSOG_RS54335" /protein_end="994" /protein_start="980" /score="18.5" /tool="antismash" /translation="LAVLKAGGAYLPID" CDS_motif 49120..49179 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0010" /evalue="7.40E-11" /label="NRPS-A_a3" /locus_tag="SSOG_RS54335" /protein_end="1077" /protein_start="1057" /score="33.8" /tool="antismash" /translation="AYVIYTSGSTGRPKGVAVTH" CDS_motif 49666..49755 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0011" /evalue="5.20E-16" /label="NRPS-A_a6" /locus_tag="SSOG_RS54335" /protein_end="1269" /protein_start="1239" /score="50.7" /tool="antismash" /translation="PAGVAGELYIAGPGLARAYVGRPDLTAARF" CDS_motif 49840..49905 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS54335_0012" /evalue="3.20E-12" /label="NRPS-A_a8" /locus_tag="SSOG_RS54335" /protein_end="1319" /protein_start="1297" /score="38.3" /tool="antismash" /translation="FLGRTDEQVKIRGFRIELGEIE" gap 49936..50123 /estimated_length=188 gene <50124..51131 /locus_tag="SSOG_RS38475" /old_locus_tag="SSOG_07633" CDS <50124..51131 /NRPS_PKS="Domain: PCP (22-91). E-value: 1.2e-26. Score: 84.6. Matches aSDomain: nrpspksdomains_SSOG_RS38475_PCP.1" /NRPS_PKS="Domain: Thioesterase (114-316). E-value: 2.8e-36. Score: 118.0. Matches aSDomain: nrpspksdomains_SSOG_RS38475_Thioesterase.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) Thioesterase" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF013166.4" /locus_tag="SSOG_RS38475" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07633" /product="alpha/beta fold hydrolase" /protein_id="WP_039939704.1" /sec_met_domain="PP-binding (E-value: 3e-16, bitscore: 58.8, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Thioesterase (E-value: 3.6e-25, bitscore: 88.6, seeds: 16, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 5.6e-07, bitscore: 29.5, seeds: 455, tool: rule-based-clusters)" /sec_met_domain="PF00561 (E-value: 6.5e-06, bitscore: 25.1, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="RRALPAPDYAVTSAGDAPRTAREAILCGLFAEVLGAGQVGVTDSF FALGGHSLLVNRLITRIRAVLGVEIPIRVVFQSPTVAELAAHLESENGPAGDADPFAPV LAITTEGDREPLWWVHPGGGLSWPYLGFAGLLPKDRPVYGIQAKGFDGSAPLPGSIAEM VADYVEEVLAVQPEGPFHLMGLSSGGTLAHAMAAELQRRGHRVALLALLDSVPSGRLAG RPLPTEADFRDYFAEHLTSLVGTEDYESFVDNAVAIGVNYTRLMRDFTAPVYRGDAVFF NAVPKPEGTYADLWRPYIHGTVHQHDIDSAHEDMYLPGPAAEICAVITHEVAGD" aSDomain 50193..50399 /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38475_PCP.1" /evalue="1.20E-26" /label="SSOG_RS38475_PCP.1" /locus_tag="SSOG_RS38475" /protein_end="91" /protein_start="22" /score="84.6" /tool="antismash" /translation="EAILCGLFAEVLGAGQVGVTDSFFALGGHSLLVNRLITRIRAVLG VEIPIRVVFQSPTVAELAAHLESE" CDS_motif 50196..50234 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38475_0001" /evalue="3.50E-03" /label="Cy4" /locus_tag="SSOG_RS38475" /protein_end="36" /protein_start="23" /score="10.5" /tool="antismash" /translation="AILCGLFAEVLGA" CDS_motif 50256..50285 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38475_0002" /evalue="5.60E-03" /label="PCP_mC" /locus_tag="SSOG_RS38475" /protein_end="53" /protein_start="43" /score="10.1" /tool="antismash" /translation="SFFALGGHSL" CDS_motif 50469..50498 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38475_0003" /evalue="3.40E-03" /label="NRPS-beforete1" /locus_tag="SSOG_RS38475" /protein_end="124" /protein_start="114" /score="10.4" /tool="antismash" /translation="PLWWVHPGGG" aSDomain 50469..51074 /ASF="active site serine present: True" /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38475_Thioesterase.1" /evalue="2.80E-36" /label="SSOG_RS38475_Thioesterase.1" /locus_tag="SSOG_RS38475" /protein_end="316" /protein_start="114" /score="118.0" /tool="antismash" /translation="PLWWVHPGGGLSWPYLGFAGLLPKDRPVYGIQAKGFDGSAPLPGS IAEMVADYVEEVLAVQPEGPFHLMGLSSGGTLAHAMAAELQRRGHRVALLALLDSVPSG RLAGRPLPTEADFRDYFAEHLTSLVGTEDYESFVDNAVAIGVNYTRLMRDFTAPVYRGD AVFFNAVPKPEGTYADLWRPYIHGTVHQHDIDSAHEDMY" CDS_motif 50649..50723 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38475_0004" /evalue="1.70E-12" /label="NRPS-te1" /locus_tag="SSOG_RS38475" /protein_end="199" /protein_start="174" /score="39.6" /tool="antismash" /translation="QPEGPFHLMGLSSGGTLAHAMAAEL" gene 51197..52495 /locus_tag="SSOG_RS38480" /old_locus_tag="SSOG_07634" CDS 51197..52495 /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: Orn_monoox" /gene_functions="biosynthetic-additional (rule-based-clusters) Pyr_redox_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1080: lysine/ornithine N-monooxygenase" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006344618.1" /locus_tag="SSOG_RS38480" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07634" /product="SidA/IucD/PvdA family monooxygenase" /protein_id="WP_009719718.1" /sec_met_domain="Orn_monoox (E-value: 1.8e-160, bitscore: 533.4, seeds: 18, tool: rule-based-clusters)" /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-07, bitscore: 28.8, seeds: 64, tool: rule-based-clusters)" /transl_table=11 /translation="MAHETEIYDVVGIGFGPSNLSLAIALEESPDPVTSLFFERQPTLG WHRGMLLPSAKMQVSFLKDLATFRNPASGFGFISYLHDMGRLTRFVNNQDFFPTRREFH DYLEWAASKLTGRVSYDSEVTAVSAVAAAGEGPADRVRVTVRGADGAPRQVEARNVVIS TGLVPRMPVNLEAGERVWHSSEFLHRFRQREGELTRVAVVGAGQSAAEIVRFLYDTLPE VRVSAVIPSFGYAIADDTPFANQVFDPDAVDSYYHGTQASKDAVWQYHKNTNYSVVDDE VIRGLYERAYEDELSGHGRLDFRNLARVLDAEPTGDGTRITVYSLVDDASYDLDVDVLI CATGYDPMNPARVLGELDKYCVHDTEGRHRVDRDYRLVTTSDLTCGIYLQGGTEHTHGL GSSLLSNIAVRSGDIAQSITARCAGAPKKGLTA" gene 52492..52707 /locus_tag="SSOG_RS38485" /old_locus_tag="SSOG_07635" CDS 52492..52707 /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1009: mbtH-like protein" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014173963.1" /locus_tag="SSOG_RS38485" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07635" /product="MbtH family protein" /protein_id="WP_009719719.1" /transl_table=11 /translation="MSTNPFDDENGRFYALVNEEGQHSLWPAFAPVPDGWRIAFGEDGR KECLEYVEANWADMRPRSLRESVTSD" gene 52730..53929 /locus_tag="SSOG_RS38490" /old_locus_tag="SSOG_07636" CDS 52730..53929 /GO_function="GO:0004497 - monooxygenase activity [Evidence IEA]" /GO_function="GO:0005506 - iron ion binding [Evidence IEA]" /GO_function="GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]" /GO_function="GO:0020037 - heme binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1007: cytochrome P450" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009719726.1" /locus_tag="SSOG_RS38490" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07636" /product="cytochrome P450" /protein_id="WP_009719720.1" /sec_met_domain="p450 (E-value: 4e-29, bitscore: 100.8, seeds: 50, tool: rule-based-clusters)" /transl_table=11 /translation="MTTPAERWGIHPEHFWLYGRRPRQMVEFDEKMNAWNVYGYAEAIE VLGDPGTFSSHMSRLLPMGADEAFTEGDLLQTDPPDHRELRKLVSHAFTPKVVAELEPR ITALTQELLDAVADRDTFDLMTALAYPLPVTVVAELLSIPSADRHLFEGWMTEIVHSLG DVSMEDAPEDQERIFEAGMAPMRKMLEYLREHAAECRRRPRGDLMGKLIEAEVDGRRLT DNHIVNFAKMLLIAGYLTTTMLIGNTVLCLDSYPEQAARVRADRSLIPGLLEESMRFLS PVAATYRATTRDVEVAGQRLSADQMVMVWFGAANRDARQFAEPELFDMTRGPNPHLGFG RGIHFCLGGPLARMEGRVALDHLLDRFPELYTDPERPPTFMPGFDTTGVSSLPLRTSLG " gene 54109..54612 /locus_tag="SSOG_RS38495" /old_locus_tag="SSOG_07637" CDS 54109..54612 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014151252.1" /locus_tag="SSOG_RS38495" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07637" /product="histidine kinase" /protein_id="WP_039939706.1" /transl_table=11 /translation="MDMTPYTDGLRREFLLAAEAAGEEALGVAERLVPSLDSAVRLTLL SALSTAAGEISRDLAPGAVDLRLRGLDPHFAVTLPWADPDAGDHPAGAGGEVLPGVEDE GAPARINFRPPEHLKARIEEAAGREGLSVNAWLVRAVAATLSGTARPGRHTPPGDQYSV GWVR" misc_feature complement(54648..54658) /note="TFBS match to HypR, L-hydroxyproline utilization repressor, confidence: weak, score: 18.59" /tool="antismash" gene 54653..55504 /locus_tag="SSOG_RS38500" /old_locus_tag="SSOG_07638" CDS 54653..55504 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF024743.4" /locus_tag="SSOG_RS38500" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07638" /product="DUF4097 family beta strand repeat-containing protein" /protein_id="WP_009719722.1" /transl_table=11 /translation="MATYDTPQPISARVEISTGTITVRASRRTDTVVEVRPTDDSNAAD VKAAEQARVDFAQGKLQVKAPPQMLNWPSASRRTGSVDVLIELPEGSDLRGSSSSVALR GEGRLGECRFEAAHGDFRIDEAGPLRLSTSRGEIAVTRAVGHARIANGSGGVRVDEIDG SALVGNDHGETRIGDATGELRLTGMNGDFHVERAHGNVVAKTAHGGIRLGEVVRGSVVV TASSAEIEIGIRQGTAAKLDVSTLTGTVRNALKVVDGPGETDEIVHVKVRTYSGDIVIH RS" misc_feature 55558..55572 /note="TFBS match to CodY, Regulator of stationary phase and virulence in Gram-positive bacteria, confidence: weak, score: 15.78" /tool="antismash" gene 55609..56517 /locus_tag="SSOG_RS38505" /old_locus_tag="SSOG_07639" CDS 55609..56517 /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1000: ABC transporter ATP-binding protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009081646.1" /locus_tag="SSOG_RS38505" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07639" /product="ABC transporter ATP-binding protein" /protein_id="WP_050800399.1" /transl_table=11 /translation="MRYGTTEVLKDVNLRVHHGEVVCLLGPNGAGKTTTLEILEGFRMR SAGRVEVLGTDPAHGGDDWRARVGVVLQSWRDHGRWRVRELLAHLGIYYAEYSTAQIRR PWDPDELLAAVGLTAQADKKVRMLSGGQRRRLDVAVGIVGRPELLFLDEPTAGLDPVAR REFHDLVERLADEQDTTIVLTTHDLHEAQKLTNRIMILSGGRIIADGTAEELAERIVGE DEVRWSHDGQSYVRSVPESTKFAFELFRKHGESITDLEIRKTTLEDTYLSLVRQSTGEQ ETVPEDAAGAASADSEGGTVR" misc_feature 55876..55878 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene 56514..57356 /locus_tag="SSOG_RS38510" /old_locus_tag="SSOG_07640" CDS 56514..57356 /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type transporter" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018837257.1" /locus_tag="SSOG_RS38510" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07640" /product="ABC transporter permease" /protein_id="WP_009719724.1" /transl_table=11 /translation="MNKTVMRAGWSRGVTELRQSFTNGGDLFNHFFWPVLMLVVLFLMR DVSFGDGEFELGTLVLPGILGMNAAMAMVTMSQLLTADREDGTLLRAKATPHGTPAYLV GKIISVSVGVVVDLAIFLIPALFIIPGLRVGSSEAWLTLGWVLVLGLVATLPIGAVLGS LFSSTRSQGLLTLPIMAMIGISGIFYPVTSMPEWVQGLAQVFPVYWLGLGMRSALLPDS AVIVEIGDAWRHLETVGVLSVWAVVGLVLAPIVLRRMARRESGSTMAERREKALQRVG" gene 57548..58741 /locus_tag="SSOG_RS38515" /old_locus_tag="SSOG_07641" CDS 57548..58741 /GO_function="GO:0004497 - monooxygenase activity [Evidence IEA]" /GO_function="GO:0005506 - iron ion binding [Evidence IEA]" /GO_function="GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]" /GO_function="GO:0020037 - heme binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1007: cytochrome P450" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009719720.1" /locus_tag="SSOG_RS38515" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07641" /product="cytochrome P450" /protein_id="WP_039939707.1" /sec_met_domain="p450 (E-value: 4.9e-18, bitscore: 64.2, seeds: 50, tool: rule-based-clusters)" /transl_table=11 /translation="MTSPVAQWEFHPGHFWMRGKRPDKIVDYDEELQLWNVYGYPESAA ILSNPKVFSSDTMRLDPIKLDEAIVEGDFAHTDPPKHRRLRGLVDHAFTPSLVAKMESR VHGIIHELLDGVEGKSQFDLVAEFAAPLPLIMISDLLGVPESDRALFRQWMDKMLDGSE KFESPETVLEQEEELHKELELLWEMRDYWHERAAESRKRPREDLISQLVHAEVDGQKLN DSQISNIANRLLVNGHLTTAMLIANTMLCLDAFSDQDARVRADRSLVPALLEESMRYMS PICGVGRATNSEVEVAGTVIPKDQLLLVWTGAANRDERQFEKPDVFDAGRSPNAHLGLG RGIHFCLGRQLARMESKAAVEILLDRLPTLRADPANPPTFLQVVDASGVATLPVVTQ" misc_feature 57647..57649 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene 58789..59982 /locus_tag="SSOG_RS38520" /old_locus_tag="SSOG_07642" CDS 58789..59982 /GO_function="GO:0004497 - monooxygenase activity [Evidence IEA]" /GO_function="GO:0005506 - iron ion binding [Evidence IEA]" /GO_function="GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]" /GO_function="GO:0020037 - heme binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1007: cytochrome P450" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009719720.1" /locus_tag="SSOG_RS38520" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07642" /product="cytochrome P450" /protein_id="WP_009719726.1" /sec_met_domain="p450 (E-value: 2.9e-33, bitscore: 114.4, seeds: 50, tool: rule-based-clusters)" /transl_table=11 /translation="MTTVVDRWNIHPDHLWLRGQRPESPVVFDETQGVWNVYGYPEAMD ILNDHDTFTSDLAHLLPVSVDAPLLEGDMSQMDPPRHRKYRQLVSRAFTPRLVADMETR VADITRELLDAVDGKPEIEIAADLAYPLPVIVIAELLGVPAGDRDLFKKWADDIIEGFS GFSFLDTSGQGEQDVRDATERLRPLLDYMAGHVTERRRTPREDLLTHLVQAEVDGERLT DNEIVNVANILLVTGHITTTMTLGNTVLCLDADPEVAAKVRADRSLVPGAIEEALRVLS PSAALARGTSREVEVAGTVIPKDQIVMLWLGAGNRDPRQFTDPEVYDPTRDPNPHFGFG RGIHFCLGAPLARLEGRVALNALFDRFPVLRTDPAKPPTFFPTPDMIGVNTLHLRTS" gene 60011..61069 /locus_tag="SSOG_RS38525" /old_locus_tag="SSOG_07643" CDS 60011..61069 /GO_function="GO:0008171 - O-methyltransferase activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1042: O-methyltransferase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF013087.4" /locus_tag="SSOG_RS38525" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07643" /product="methyltransferase" /protein_id="WP_050800098.1" /transl_table=11 /translation="MSADAGAAEAAPTEQSLSQIALGFVPARILYSAAELGIADALANG PRDYESLAKETGTDPGALRRLLRALAGLGVVRQLDTDRFSLTEFGGRLRSGTPDSERDD IMLSTAPELWAAWGELTAVVRSGEPARAPGTGRTAYEAMQEQPEVSAKLRAGMAQASAL FATGVAEAYDFSRFRTVVDYGGDEGTLIAAVLTAAPDLRAVLYDRPEALERSTATLSAA GVADRCEVVEGDLTSPPPSGADACVLNNIVRDRGDEKATELLRSLRAGLAPTGRILLVE TLMPPVLTPDESAAYGLTDLNNLVFAGGRERTRDEYAALLAAAGFTLGATVRVPVPTGM PDYHVIEAAPTS" CDS complement(61085..>62747) /codon_start=3 /gene_functions="regulatory (smcogs) SMCOG1041: transcriptional regulator, SARP family" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014146409.1" /locus_tag="SSOG_RS56805" /note="incomplete; too short partial abutting assembly gap; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07644" /product="AfsR/SARP family transcriptional regulator" /pseudo="" /transl_table=11 /translation="GSRTALPRHKTLRAVVDWSWELLTDAERMVLRRLSVFSGGASLEA AERVCAGDGVEREQVLELLTALTEKSLLLAEGGGTPRYRLTGMIQEYAGQRLAEAGEAD LARHAHLAHFTELAETAEPQLRRAGQLEWLARVEAEHDNLGAAMRGALAAGEARAAMRL AAGGGWYWWLGGRRTEGIELLTAAAGLPGEVADEVRATVCALIAGFVTSGLSDERRAAE WIHEAYRLSRHGRRSHPGLRLVAVLERMLQAPESSLSAFEPLLDDEDPWVRALARWHLG KMRIALGRDGQDGHDAGAYLEGALAEFRALGERYGISLALSELANLLALRGEFAGACER YEQAIAVVTEVGATEDVIRMRSWQAQLYWLLGDEDASAAAMAEAGRCAERVTWPDALAE LALSKAGLARWSGDTEEVHRQLGVAAALLGDDAEQADIRAVTHDLLGYLADDLGEARAH RAAACAAASETGHAPLIAHVLIGVADLALRRDEYEQAVRLLAASTGVRGLRTRSHPDMA RIERTARRRLGDVRFAEATREGTRVRWSQLVEVTLAT" gene complement(61085..>62751) /locus_tag="SSOG_RS56805" /old_locus_tag="SSOG_07644" /pseudo="" gap 62752..62851 /estimated_length=unknown gene complement(<62852..64297) /locus_tag="SSOG_RS56810" /old_locus_tag="SSOG_07645" CDS complement(<62852..64297) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1041: transcriptional regulator, SARP family" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014146409.1" /locus_tag="SSOG_RS56810" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07645" /product="BTAD domain-containing putative transcriptional regulator" /protein_id="WP_009719729.1" /transl_table=11 /translation="MQIGMLGPLEVRTDDGGSADVPGARLRGLLVALALKPGHVVPKAS LIDWIWGEHPPADATNALQRLVSRLRKALPGAVVEGRTEGYRLAVEPDAVDAVRFERLV TAGRSRTEEPPRRARLLGEALGLWRGAAMQDIGLRESAAFDAAVARLQELRLTAAEERA DAEVALGHGAEMVTELTDLVAAHPLREPLVAALMRALAAAGRDSEALLVYQRTREALAD ALGVGPSPELAALHIALLRGELRQGPGQREESRKTNLRAELTTFVGRGADVAAVRGLIA EHRLTTVIGPGGSGKTRLATETARTLLGDLPDGAWLVELAAIGADGDVAQAALTGLGLR DTLLGGAPKAELADRLIAAIRERDALLILDNCEHVIEAAAVFAHRVLGECRRLRILATS REPLGITGEALWQVEPLGLPEGDASPDEIESSPAVQLLRDRAGAVRRDLAVGHRTTMAR VCRALDGMPLAIELAAARLRTMSI" misc_feature complement(64314..64323) /note="TFBS match to AbrC3, Antibiotic production activator, confidence: strong, score: 18.16" /tool="antismash" gene complement(64346..65791) /locus_tag="SSOG_RS38535" CDS complement(64346..65791) /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_function="GO:0015295 - solute:proton symporter activity [Evidence IEA]" /GO_process="GO:0015718 - monocarboxylic acid transport [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014056497.1" /locus_tag="SSOG_RS38535" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="gluconate:H+ symporter" /protein_id="WP_039939710.1" /transl_table=11 /translation="MTAHTWFLLLTLMVGFSALIFLINSRLRVHPFVALIIVAVGTGLA AGEPVATLTESIEEGAGSTLGDVGLTLALGAMLGRLLSDSGATDAIAHAIVDRSSTRRL PWLVVAAAFVIGIPMFFEIGLIVLLPLIFSVARRLEDRGGTNGSPYVLLGVPAIAALCT LHGMLPPHPGPLTAMTGLHADLGLTLAVGIVCAVPTVILAGPVYARWIAPRLADVRPDA TLVTQFTGAGRHAGPEPTPAVASAGPGAQHRDEIRPRAGVPTGLAVTAVLVPVALMLLR AVAETALDESSRLRAALTFAGEPLVAMGGGLLFALGVTLVHQGRSGEETRTSLNDSLKS VATILLIIGGGGAFNQVLQDSGIGDAIASAAKGAHVNVIVLGWLIALLLSLTTGSATVG IVSATGIVAPLIGTGGGLEASLLVVAIGAGSLGLNYVNHAGFWLVKESFGMSLTQAAKT QTAVQTLVSVLGLGMALLLSILA" gene complement(65847..67124) /locus_tag="SSOG_RS38540" /old_locus_tag="SSOG_07647" CDS complement(65847..67124) /codon_start=1 /gene_functions="transport (smcogs) SMCOG1074: major facilitator family transporter" /gene_kind="transport" /inference="COORDINATES: protein motif:HMM:NF019310.4" /locus_tag="SSOG_RS38540" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07647" /product="MFS transporter" /protein_id="WP_009719731.1" /transl_table=11 /translation="MFAWYRDTDRPQRRAFWAAFGGWTLEAADAQLFGLVLPTLMTAWQ LSTGAAGRLASITLICTAIGGWLAGWASDRYGRVRVLQWTVLVYSTATVLIGFTTGYSQ LMVLRSVQGFGFGGEWAAGAVLVSEYMGTRHRGRALGAVQSGWAVGWGLALAAYTFLFT ALPEQWAWRSMFWLAALPAVLVIVIRRKVTDPPIYQQRVATSGNRVSLLRIFRTDLLRV TLLGGFLGLGSHGGYYALTTFLPTYLRTEHHLSVLKTSSYLAVFIAAAFFGYVVSGFLA DRIGRRRNIVFFAAMCLVSVVVYLFVPITETQMFFLGIPLGFFSAGIPAGLGSLFAELY PTAMRGTGQSFCYNFGRIVAAAFPALVGYLSDRIGVGASIGLFAGTAYGIAVVAALLLP ETSHRELDRPAALRAHDEQVPQPTGA" gene complement(67171..67842) /locus_tag="SSOG_RS38545" /old_locus_tag="SSOG_07648" CDS complement(67171..67842) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1136: GntR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: protein motif:HMM:NF019322.4" /locus_tag="SSOG_RS38545" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07648" /product="GntR family transcriptional regulator" /protein_id="WP_050800099.1" /transl_table=11 /translation="MIAERVRAGEWAPDQPLPAESTLVAYYDVSLGTIRRAFRDLVEEG LLERRQGSGTFVRRASLTASLFRFFRFGTAGDGFPQSRILSIARQVGTQTITSALGLEA GSEVLHLHRLRLYEEKPVLVEDIWLPLPLFEPMERIGQDDLGDLLYPLYERTCGQIVAA ATEELTVDVATAGDALLLQCARHDPVVVIDRVARSHDATPLEYRRSRGLARTFRYRIDL R" gene 68078..68890 /locus_tag="SSOG_RS38550" /old_locus_tag="SSOG_07649" CDS 68078..68890 /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF016777.4" /locus_tag="SSOG_RS38550" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07649" /product="amidohydrolase family protein" /protein_id="WP_050800100.1" /transl_table=11 /translation="MRFAPTRRYTPDYDATPDTYLSLLDTHGLDGGVLVQPSFLGTDNS YLLEALGKAPHRLWGVAVIDPGTSRDELDRLVRAGVCGIRLNLVGRPVPPLHEAVWQRL GRALAARNLHLEVQARAEQWNELSPWLLRWPGQVVVDHLGLPLDTTLSSPGAKALVSLL TADHVWVKASAPYRSARAAASAMLHHVLDTAGPARTLWGSDWPWTQHEEGRTYADTLSW LMRQLSATEITQVLCANPLRLLTGGRAGDLAAPVGGSVSRRSSRKLRG" misc_feature 69167..69180 /note="TFBS match to MogR, Repressor of flagellar motility genes, confidence: weak, score: 16.95" /tool="antismash" misc_feature 69168..69181 /note="TFBS match to MogR, Repressor of flagellar motility genes, confidence: weak, score: 19.05" /tool="antismash" misc_feature complement(69169..69182) /note="TFBS match to MogR, Repressor of flagellar motility genes, confidence: medium, score: 22.42" /tool="antismash" misc_feature 69169..69183 /note="TFBS match to CodY, Regulator of stationary phase and virulence in Gram-positive bacteria, confidence: weak, score: 17.5" /tool="antismash" misc_feature 69193..69207 /note="TFBS match to VqsM, Regulator of quorum-sensing signalling systems, confidence: medium, score: 18.37" /tool="antismash" misc_feature complement(69213..69228) /note="TFBS match to CopR, Copper-responsive regulator, confidence: weak, score: 19.69" /tool="antismash" misc_feature complement(69268..69281) /note="TFBS match to ArgR, Regulator of arginine biosynthesis genes, confidence: weak, score: 17.22" /tool="antismash" gene 69329..70126 /locus_tag="SSOG_RS38555" /old_locus_tag="SSOG_07650" CDS 69329..70126 /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1041: transcriptional regulator, SARP family" /gene_kind="regulatory" /inference="COORDINATES: protein motif:HMM:NF015649.4" /locus_tag="SSOG_RS38555" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07650" /product="AfsR/SARP family transcriptional regulator" /protein_id="WP_063631615.1" /transl_table=11 /translation="MGYSKGKSVQVLGMLRIADDGEVESLALAHKPRTVLAMLVAHPDQ VVSLPALVRELWGDHPPASALRVVQTYILQARKALSQATRLPIKVIIQEALTTHAGGYM FSESFARLDYRIYQGLVDSGRKALANGDLSAGVSYLGDALGIWRGSAFADVVVGRMLES RRRQYEESRLGALETLAEAKIEIGRHLEVTADLAALTTEYPYHEGLHSQYMRALEKAGR RAQALEVFHRLRVGLVSELGIEPGHTISRLQYSILNSSPVNGV" misc_feature 69494..69496 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene complement(70175..70924) /locus_tag="SSOG_RS38560" /old_locus_tag="SSOG_07651" CDS complement(70175..70924) /EC_number="1.-.-.-" /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /NRPS_PKS="Domain: PKS_KR (8-183). E-value: 2.1e-11. Score: 36.0. Matches aSDomain: nrpspksdomains_SSOG_RS38560_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (smcogs) SMCOG1001: short-chain dehydrogenase/reductase SDR" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009717248.1" /locus_tag="SSOG_RS38560" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07651" /product="SDR family oxidoreductase" /protein_id="WP_009719735.1" /sec_met_domain="adh_short (E-value: 1.1e-31, bitscore: 109.4, seeds: 230, tool: rule-based-clusters)" /transl_table=11 /translation="MESTLTGKTIVITGAGSGIGRATARAFADHGANVLAVGRTLEKLK ATAKGRPSITPVTADISEVDAPQAIISEAVAAFGGIDILVNSASVFRPTHLGMITPSEF DQFIAVNLRAPLLITQAALPCLERAEGTVVNISAAIGQHGWPGLCVYGATKAALDFFTR SWANELAQSCVRVVSVAPGPIETPILENNALDDQAVMTIHQTQEQIPMGRLGTAEEIAW WILNFTDPLASYATGAIFAVDGGYTVA" aSDomain complement(70376..70900) /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38560_PKS_KR.1" /evalue="2.10E-11" /label="SSOG_RS38560_PKS_KR.1" /locus_tag="SSOG_RS38560" /protein_end="183" /protein_start="8" /score="36.0" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C2" /tool="antismash" /translation="TIVITGAGSGIGRATARAFADHGANVLAVGRTLEKLKATAKGRPS ITPVTADISEVDAPQAIISEAVAAFGGIDILVNSASVFRPTHLGMITPSEFDQFIAVNL RAPLLITQAALPCLERAEGTVVNISAAIGQHGWPGLCVYGATKAALDFFTRSWANELAQ SCVRVVSVAPGP" misc_feature complement(70481..70483) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" CDS_motif complement(70820..70900) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38560_0001" /evalue="5.30E-07" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38560" /protein_end="35" /protein_start="8" /score="22.3" /tool="antismash" /translation="TIVITGAGSGIGRATARAFADHGANVL" misc_feature complement(70910..70912) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" misc_feature complement(70952..70970) /note="TFBS match to HgtR, Hydrogen-dependent regulator, confidence: weak, score: 19.04" /tool="antismash" misc_feature 70955..70973 /note="TFBS match to HgtR, Hydrogen-dependent regulator, confidence: weak, score: 18.28" /tool="antismash" gene complement(71047..72276) /locus_tag="SSOG_RS38565" /old_locus_tag="SSOG_07652" CDS complement(71047..72276) /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /NRPS_PKS="Domain: AMP-binding (27-375). E-value: 9.7e-47. Score: 151.4. Matches aSDomain: nrpspksdomains_SSOG_RS38565_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012711.4" /locus_tag="SSOG_RS38565" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07652" /product="class I adenylate-forming enzyme family protein" /protein_id="WP_078510508.1" /sec_met_domain="AMP-binding (E-value: 2.5e-29, bitscore: 101.2, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MAAYVDPEPDWWGADLLGAPPGSALWAQAGHGVTYQTLRTQVAQM RRLFDAYGIRSGHTVALQGAHSFSQLWALFALWSCGAQVMLMGPHVRGKELGRQLDWCR PQFHVSFDAPGHGQETFHDECEVFVRRLLRGRPAATDHCLVQFTSGSTGFAKAIGRTPE SLLTELERFKTVGGMPEPRSRVLVLGPLAHSFSLVGGVLYATSTRSTVLLAPHSGRRTV LRTAIRSGADTIIGSPQHFAALAQIDRPVRIPRLRLAISGGEQMAHRVYTRFAERHRVR IGQAYGTTETGIIATDPTGWYGPDTVGMPVPGLQLRLVDGELQVRLDRSPYLPQAGPPG RFLPDGEHTLAGWLRTRDLVEQDPSGALRVLGRFDPLADRRALTRGLDQILLADRTLVR HFERDGHPVG" aSDomain complement(71152..72195) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38565_AMP-binding.1" /evalue="9.70E-47" /label="SSOG_RS38565_AMP-binding.1" /locus_tag="SSOG_RS38565" /protein_end="375" /protein_start="27" /score="151.4" /specificity="substrate consensus: X" /tool="antismash" /translation="QAGHGVTYQTLRTQVAQMRRLFDAYGIRSGHTVALQGAHSFSQLW ALFALWSCGAQVMLMGPHVRGKELGRQLDWCRPQFHVSFDAPGHGQETFHDECEVFVRR LLRGRPAATDHCLVQFTSGSTGFAKAIGRTPESLLTELERFKTVGGMPEPRSRVLVLGP LAHSFSLVGGVLYATSTRSTVLLAPHSGRRTVLRTAIRSGADTIIGSPQHFAALAQIDR PVRIPRLRLAISGGEQMAHRVYTRFAERHRVRIGQAYGTTETGIIATDPTGWYGPDTVG MPVPGLQLRLVDGELQVRLDRSPYLPQAGPPGRFLPDGEHTLAGWLRTRDLVEQDPSGA LRVLGRFD" ORIGIN 1 gtatccggcc tgggcagcct cgtcgaggaa ctgctgccag ggcacctgcc gcgggtcgtc 61 ggggaaccag acgccccagg agtcgggcgc ggtgcccaga cgcagattgc tcagtgcgga 121 tggggtgggt gaatggactt cgtcgctgtt catggcgttc cctgtggtcc ggagatcagg 181 cggccactgc cgacgtggtg ttccgggtgg cggagcgggt cacggcctcc agaacgtcga 241 ggttgtgcag cccttcggcg aaggcggcgc agcgggggat ctcctccagc ccggcgacct 301 cgtcgaggaa cgcgcgcgcc tggtacacga agctgtcgtt gtggccgacc ccgatgccat 361 tggcgtccat ggccatccca ccggcgatgt acggatgctc gacaccgacg atcacccgcc 421 ggaagccgtt gaccccaccg ggcagatcgc cggtggcgat cgcgaactcg cccggccggc 481 tctggtcgta ggagagcgcg ccgttctcgc agaacacctc gaacttgagg gtgttggggt 541 gtccgaaggc gatacgggag acgctcagat caccggtggc gccgctggcg aagcgggcgc 601 agtagctggc ccagtcatcg ttcccgaccg gttcgcgctc gtcgctgacc tcgacgtgtg 661 cgtgtccgac cacatgaccc agcggcagtg gccgctcggt gatcgtggtc gagagcgccg 721 caccgtggac ggtctccacc ggtccgagca ggaactcggc gacgtcggtg aggtggctgc 781 cgaggtcggc cagcgcaccc gagccaggac cgccgcggta acgccagctc atcggggcct 841 gcgggtcgct gccgtagtcc gtccagtact gcgcgctcac gtgcaacggg cggcccaagc 901 ggccggaccg cagctgctcc cgcaccgcgc cgatgcccgg ggcccggcgg aaggtgaaac 961 ccacccgggc cacgatgccc gccttctcgg tgtcggtgat catcgcgcgg gcgtcctcgg 1021 gggagggggc caggggcttc tcgcacagca cgtgcttgcc cgccgccgcg agctcccgga 1081 cgatctcccg gtgcaggtcg ttggcgacga cgacgctgac cacatcgatg tcgtcggcct 1141 tcacgaccgc ttcccaactg gtgtcggcgc gctcgaagcc gtaacgggcg gcggtgtcgc 1201 gcgccaggtc cccgttcaga tccgcgatgg agaccagccg tacgggaggc agcccggccg 1261 agaagaccgt gcccgcggac cggtagccgt gagcatgggc ccggcctgcc attcccgctc 1321 cgatgacggc gacgccgatg tcctgactca tgtgaactct ccacgttgca aaggcagtga 1381 gaccggtggt ccaccggtct ggatcgatct actagatcga gctactagct cgatctagtt 1441 ttggtagtct gaggagcgtt cccccgggcg tcaaggggtg agcggaaggg agttcgtccg 1501 atggccgggc aggaccgaac gcgcggcaac gccccgggcg gccgggagcg caagccgacg 1561 atggccgacg tggccaggca tgtcggggtc tcccgcgccc tggtgtccat cgtgttccgc 1621 ggcgccgagg gcgcgtccga ggcgaccaga cagcgggtcc tggaaggtgc cgccgcactc 1681 ggctaccggc gggactcgct cgcccggggg ctgcgcagca accgcacccg caacctcgga 1741 atcctcttcg acctgcgccg tcccttcgag gtcgagttcg tcgagcacac ctacccggcc 1801 gtggagaaat acggctacca cctgctcctc ggcgcggtca ccccccatcg gaaccaggcc 1861 cgcgtggtgg aagagctgct gacgtaccgc tgcgaggggc tgatcgtgct ggggcctgag 1921 cccgacggcg accgccttga atccatcgcc gacgaagtac ccctggtgga ggtcgggcgc 1981 ggggtcactc cggggcgggt cgacgtggtc cgcaacgacg acgcgctcgg cacgcggcag 2041 gccgtggacc atctcgtcca cctgggccac cgcgccatcg cccacatcga cggcggcacc 2101 aacccgggag cgcgggaccg tcgcgccgga taccgcgagg cgatgaccga ccacggcctg 2161 gcccacgaga tccgcgtggt ggccggtggc tacaccgacg aagccggggc gacggcggcg 2221 cgccaactcc tcgccgaggg gctgccgacc gcggtcatca cggccaacga ccaggcggtc 2281 atcggcctgc tggacgtcgc ggtcagggcc ggtctgcgca tccccgagga cctctcggtg 2341 atcggatacg acgactcccg gttcctcagg ctgcccggga tcgacctcac gtccgtccgt 2401 caggacattc ccgcgatggc cgaactcgcg gtccaggcag cggtcgagcg gatcgagctg 2461 ccggagacgg aaccgcggag cgtcgccctg ccgcctcaac tcgtcgtgcg caatacgacg 2521 aagacaccga agaacgccga gtagggacgg agcgcgtcag ccgacgtgga cgtgagggcg 2581 gcgggcgcgg tcgggttcgg cttcgcggag gacttcgcgg gtcacggggg cgacctcgcc 2641 ctggccgaac aggaagaacc gcaggaactg ggcgaagggg ctgccttcgg tccactcgaa 2701 gtagatgtgc ggcctgcacc cggtctcgtc gcgtacgtgc agcagcaggg cggccagtga 2761 gttggggatg ctggagccgt cgagggtcag gacgcggtag cggccgtgca gcacctcgcc 2821 ccgtacccgt accgcggatt cgaagtcgga ggggtcgcgg acggtgacct cgacgaagac 2881 gaggtcctct tccgccggga tgtcgttgtc ggcgcgtatc tgctgggtct tgtcgcggta 2941 ctcggccggg tcgcggttgt cgggctcgtt ggcgatgaac cgtatccggc gggtggcggt 3001 gtcccggacg aagcgctcgg ccaggtcgtc cagctccatg tcggtgaccc gcagctcgaa 3061 ggcgcgggcg agccgggaca gcagggacac cgcgataatg cccgcgatga aacacgcgcc 3121 gatcttcaca ccgtcggggc gttccacgac gttgacggcc gtggtgtaga cgaagaccac 3181 ggagatggtc ccgaaggcga tggtccagcc ccgctgccgg gcgcggcggg cggcgatggt 3241 gacggcgacg gcggcggagg tcatcaggac cagcactccg gtggcgtagg cgccgccctg 3301 ggcgtccacg tcggcgccga agatccaggt gaccaggaag gcgatcaggg tgaagacgag 3361 caccatgggg cggaccgcgc gggcccagtg cggtgccatg ccgtaccggg gcagatagcg 3421 cggcatgagg ttgagcagtc cggccagcgc ggaggcgccc gcgaaccaca ggatgccgat 3481 ggtggcggcg tcgtagacgg tgccgaacac cgagcccagg tactggtggg cgaggtaggc 3541 cagggcgcgt ccgttggccg ggccgcccgc cttgaacgcg tcctgcggta tgagcagggt 3601 ggtgatgaag ctggtgcaga tcaggaagcc gctcatgatc accgcggcgg tggtgagcag 3661 cttccgggtg tcccggatcc ggccggtggg ccgcgcctcg gtgtcgccgg ggtcgccctg 3721 gacgtggggc atgaccgcca cgccggtctc gaacccggac aggccgaggg cgagcttggg 3781 gaagaccacc aacgccagcc cgaccatgac cagggggttg ctgtgctggg cggtcagcgc 3841 ctgcgaccag tcggtgacga cgtgggcggc ggtggccaca tgccacagcc cgacgatcac 3901 cacgaccgcg ttgagcgcga gatacgcacc caccagggcc accgccacgc cgatggcctc 3961 ggtgaacccc ttgaggaaga cggcgccgag cagggccacc agacccatgg tgatggcaac 4021 ctcatggccg tggaggaggc tggtgaagtg cgggttctcc accaggtggg tggaggcgtc 4081 ggccgcggag agggtgatcg tgatcaggaa gtccgtcgcg gcgaagccca gcagcgtcag 4141 cacgaagagc ttgccctgcc agaacgacag cagccgctcc agcatcgcga tcgacccctc 4201 gccgtgcggg ctctccttgg ccacccgccg gtacaccggc agcgccccgg ccagggtcac 4261 ggccaccagg acgagcgtgg cgatcgggga gagcagcccg gcggccaggg cggcgatacc 4321 gggctggtag ccgagcgtgg agaagtagtc cacgccggtc aggcacatca cccgccacca 4381 gcgctttccc tggtgtccct cggagggctg ggcgtgtggg cccggctggc gcttggccat 4441 atcggccagg ccctccagca tccaggaccg caggcgacca ccggaagggt tctccggagg 4501 ggtctccaca tcggtggagg ttgccatcgt gcactcctgt cacatcacaa ggaacaagcc 4561 gctcaaagag cggtccggcc agcgtaagcg ccgctgtccg gcatatgggg gtcagggggg 4621 ttgcgttacg gaacgtcctc ggcgggtcac aggtgccgag cgccgtcagc tttcgcaagt 4681 gcgagggatt gatggcctgt tggcttgcac aagctgggtg atcaggcggc atgggtcgta 4741 tgtgcgtttg ggcgggaggt cggttcgggt acggtcaccc gggagtacgt gaagaacatc 4801 aggagaggct catgagcgcg ccagcacgcc gtacggatgc ggtgcagaac cggacccgca 4861 tcgtggaggc cgcccgcgca gccctcgccg agtcccgcca cgtccacctc aacgagatcg 4921 ccaagcgcgc cggggtgggg cagggaacgc tctaccggaa cttccccaac cgcgaagcgc 4981 tcctggccga ggtctaccgg cgcgacgtcg aagaactcgt gagcgccgcc tccgccctgc 5041 tggcggagca cgagcccgtg gaagccctgc gccactggct ggaccgggtg atcgactacg 5101 ccgagatcaa gcgcggcgtc ctggcggcgc tggagccggt ggcctggcag gatctcgtcg 5161 cccacagcca caaccccatc gaaggcgccc tcgctcagct gctggacgcc gggaaagcgg 5221 ccggttccct ccgcacggac gtggacgccc acggggccct gctgctcatc gcctacctcg 5281 gccggctgga gcggggtgag tgggagtcga cggcacggcc cctgatgaac gttatcctcg 5341 acggccttcg ccgaccggac gcggaccggt gagcgcgttc cgtcaaagga tgtacatgcg 5401 tttcctcccc taggacgacg gtcatgacgt ggcggcaggt gaggctggag agcgcctgag 5461 acgcccagcc gcgagccgag agccgggaga accatgtccg cacttcgcca ccgagtatcc 5521 gtgtccgacc gtggcggggc cgtggcccgg gccctgggcg gtggcctcgt gatggccgtg 5581 gcgcttggtg tcggcaccgg gctcggcccg gccctcgccg acgcctgcgg ggtcggcggc 5641 ttgtcggctc ggctggtccc cgcagcgctc gtcagcgctg tggccgtacc cctgatcctt 5701 cgcgtggcac gccccggttc actcggtttc ggaaacgcgg gctcgcgtct gcgtgccttc 5761 ctcatcggcg tcggcgtgac ggccgccgcg gcggcgctcg tgctgggcgc gggcacggcc 5821 gccgggatgc tggagtgggc gcgacccgat cccgcggccc tcgtcggctt cgtcgtctcc 5881 aacgcactgg tcgcgttcct gctcgaagcg ctgcccgagg agaccacgct gcgcggctac 5941 gcctggacgt cactgcgcga gcggttcggg gcgatgggct cggcgctggg caccacggca 6001 gtcttcctgt tggtgcccgg tgtctcgacg gtggtggagg ccggggtggc gcggctggtc 6061 ggcgaggagc ctccgccgat cgggccggcg ccttccgggc cagcatccgg tcgactatct 6121 cgtccttctg accgtgttcg gcctgatgct cgtcgccgcc aggacggccg tggccggggc 6181 tccgctgtgg gccacgatag gcgcacacct cacctttctg accatcaacc gggccgtgct 6241 ggaaggcaac gagcgcgatg cgggtgtgtc cgtggaccag acgacaccgg acgcggtgct 6301 gctcgtcccc gcgtatctgc tggtcgccac cgtcgcgttc ctcgcgtatg gccgcatcgc 6361 acgtcggggc tccctcacgg cctcatccga tttgccgcgg cctgatgggc aaccgtacgt 6421 tcgccaccat ggcggatgac gaacacacgc gcgcggcgcg gttgctggaa gcccaggcga 6481 aggcggaacg gctcttcgcg gaggtcgagg agcgtgggct cctcgcgccc ggcgagggcg 6541 agcgggcggt cagcgaccgg atccgggatc tggccaacga gatgttcggt acgacccgcc 6601 actggcacaa gcgaatcgtg cgctcggggc cgaacacgct gatgccgtac cgggagaacc 6661 cgccggaccg cgtgatcggc gcggacgaca tcgtgttcgc cgacttcggg ccgatcttcg 6721 aggagtacga ggccgacttc gggcggacct tcgtcctcgg cgacgacccg gtcaagcagc 6781 gcctgcggga cgatctggcc gaggtcttcg cggcgggcaa gcgttacttc gagagcgacc 6841 cggacatcac cgggaagcgg ctgcacgccg aggtcgagcg gctggccacc gaggccggat 6901 gggagctggg cggctggcac gccggacacc tggtcggcga gttcccgcat gagacgatcg 6961 acggcgcgga cacggagtcg tacatcaccc ccgccaacga caccccgctg cgccgcaccg 7021 acaagtccgg gcgccactgc cactggatcc aggagatcca tctcgtcgac cgggaacggg 7081 gattcggcgg cttctacgag caactgctca ccctgagctg atccacctct ctacgcccct 7141 ccgccccgcc cgcgggagcg ggcctgatgg agccggacct tggcgcggtt tccgcagcgg 7201 tcatcgagca ccagcgccgg tttcgacgac taccgcgcct gaggcgggtg gattcaggcg 7261 ttcgagccgg tcgcggtgcg ccggaactcg ctcgggttgg cgcctcgtac ccgcttgaac 7321 gccgcgctga acccgaacgg gtcggcgtac cccacggtgc gggcgatgtc cgcgatggtc 7381 gcggcctcct gctcgaccag gaggtcggcc gcgagcgtca tgcgccagcg ggtgaggtag 7441 gtcagcggcg gttcgccgac caggtcggcg aaccgcttgg ccagcgtcga acgcgacacc 7501 ccggtgcggt cggccagcgc ggcgaccgtc cagggtgccg ccggttcggc gtgcagcagg 7561 cgcagcgcgt cgccgaccac cgggtcccgc tgggcggccc accaggccgg gggctcgccg 7621 ccgggccggt cgaaccactc ccgcagcgtg cagaccagca tccagtccag cagccggtcg 7681 aggacgacct gttggcccgg cgtgtcgacg gcgacctcgg cggcgacgtg gtccagcacg 7741 gcgtcggccg tgcccccggc gcctacgcgc agtacgacgg gcagcgcgtc cagcagtcgg 7801 cggctgatct cgccgcgcac cggataggcg ccgacgatca gggtcgtcgc accgcggccg 7861 tcaccggcgt cgtcctcgcc gcagtcgttc cagccgagcc ggtgccgggt cccgccctgt 7921 tcgggcgtcg cgcagtgctc gccgcatgcg agcggttcgg ccggggtgtg gagctcgtcg 7981 acgaaggtga acgtcgcggg gccgcgtacg acgatcgtct cgcgggcgcg aagcagctcg 8041 ggcggacgcc cctccggcac gatccagccc gccccggtga ggacggtgca cagggtcagc 8101 ggcgcgccgt ccacgaagtg gagggcccag ggcggggtca gggtcgagct gccgaacaac 8161 gagccgtggg ctcgtacccc ccggatcaga tcactgaacg cgtccacctc agcgagtcta 8221 gacgcatacg ttgagacgaa tacacaggcg atccggcttc ttgcccatgg gatcgtccga 8281 gtcggccgtg ttcaatcgac gtcatgagca acagcaacga caccactctc gtcctcggcg 8341 caaccggcaa gacggggcgg cgggtcgccg cccggttgcg gctgcgcggc acgccggtgc 8401 gcgccgcctc ccgatcgagc cggacccggt tcgactggtc cgaccccggc ggctgggacg 8461 cggccctgcg ggatgtggcc gccgtctacg tggtggcccc gcaggtgccg ggcccggtgc 8521 acgagttcgt ggcccgggcc gaggccgccg gagtgcggcg gctggtcctg ctctccgggc 8581 acggcgcgga cacctggggc gactccacgt tcgggctgga catgcggtcg gccgaggatg 8641 ccgtacgcgg ctcggcgctg gagtggaccg tcctgcggcc gtcgaacttc gcccagaact 8701 tcgacgagga cgtcttccac gccccgctgg tcgccgggga actggcgctt ccggccggtg 8761 cggttcccga gccgttcatc gacgtggagg acgtcgccga cgccgcggcc gcggtgctga 8821 ccgagcccgg tcggcacgcc ggacggatct acgaactgac cggaccgcgt gcgatcacct 8881 tcggcgaggc cgtcgagctg atctcccggg cgtccgggcg ggccctcacg taccggcgga 8941 tctcgcccgc cgagtacgcc gcgacgctgg tcggggaggg cttgagcgag gacgacgccc 9001 accacgtcgc cgagatgttc gtgatgatgg aacgcggact gatcgccgcg acgacggacg 9061 acctcgccac cctgctggga cgggcgcccc ggaccttcga ggactacgtg gtgcgggccg 9121 cggcggcggg ggcctgaggg cgatgatcgg caactaggga gagacctcag tcgggcagtt 9181 tccggaagga cccgtgcaga ccgacccccg agannnnnnn nnnnnnnnnn nnnnnnnnnn 9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 9301 nnnnnnnnnn nnngtcgcgg cgggtgtaac ccggttccag tgcgcccggt gtacgcgctg 9361 gtgggctcgc aggtgggacg acgtcgtccc aggcccggtg catgggggtg aggacgtggg 9421 ccacctggtc gccgtgcggg ggcgcggctc ggccgaccac ccaggcgtgc ggggtgtcgc 9481 aggccggaca gcgggtggcg accaggacgt cgggctcgtc cctgagcagg tgggggaggg 9541 cgaacgagtc ccaggcgcag ccgccccacc acagcgtgtg cgcccccatc acggagaagc 9601 cgagcggcac ggacgcgaac gggtgggcca tgaccacccg gtcgtggtcc cgcgggtcca 9661 ggaccacgtc atggctgtca tgaagggcaa gggcgcgcag ttcccgacgc acctcgtcgg 9721 cggtgagttc ggtgagcgcg gcgagttccg gcacgcccgg agcacggccg gtgcggggtg 9781 aggcgatggt gtccaggatg cgccgcgagg aggccgggag acttgaacgc ccgtgcgaca 9841 ccgagcgggg cgcatcgtcc caggtgatgc ggtgaaaggc ggcggaccct atcgcgttac 9901 ggtgtggaac cgacagcgac ggttgagggc ctcctcatgt cacccaccga gcggtcgagc 9961 gtccgtccgc ggcggacctc gacgtgcgac acgattccag agagaacccg atgagaaaga 10021 tcatcctcga ctgcgacccc gggcacgacg acgcgatcgc gatgctcctg gcgcacggca 10081 accccgacgt cgaactggtc gccgtcacca ccgtcgtcgg caaccagacc ctcgagaagg 10141 tcacccgcaa cgccctctcg gtcgcccgca tcgcgaacat caccggcgtc cccttcgccg 10201 cgggctgccc ccgccccctg gtgcgcaccg ccgaaacggc cgccgggatc cacggcgaga 10261 gcggcatcga cggccccgcg atgcccgagc ccaccctggc cctggacccc cggcacgccg 10321 tcgacctcat catcgacacg gtgatggccc atgagcccgg cgagatcacc ctcgtcccca 10381 ccgcgggtct gaccaacatc gccctggccg tacgcaagga gccccgcatc gcccagcgcg 10441 tgcgcgaggt cgtcctgatg ggcggcggct accacacggg caactggagc cccgtcgccg 10501 agttcaacat caagatcgac cccgaggccg cccacatcgt cttcaacgag agctggccgg 10561 tcaccatggt cggcctcgac ctcacccacc aggccctcgc caccccgcag gtcgtcgacc 10621 gcatcgcccg cgtcggcacc gggcccgcca cgttcgtcaa tgaactcctg gaattcttcg 10681 gcgccatgta cctcaaggag cagggcttcg aacacccccc ggtgcacgac ccgtgcgccg 10741 tcgcgtacgt catcgacccc gccgtcatga ccgtccgcaa ggccccggtg gacatcgagc 10801 tcaccggcac cctcaccctc ggcatgaccg tcaccgacct ccgcgcgccc gcccccgacg 10861 actgccacac ccaggtcgcg gtcaccctcg accaccagcg cttctgggat ctgatcgtgg 10921 acgccctcga gcggatcggn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 10981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnc 11041 cacccgcgcc ccgggggcag accgggcggc acacgacccg tccggatctg ggtccggaca 11101 ccgcgctcct gacgggctgc ttcgccttcc agctcaacgc gagcatgctc agccccgccc 11161 tgaagagcat cgaggactcc ctcggggcga cctcggccga aggggggcct gaggcagacc 11221 gcgttcttca cctcggcggc cctcttctcg ctcttcctgc cccgcctggg cgacctcatc 11281 ggccgccgca gggtcctggc cggaatgctg gcgctgatgg ccgtcggctg tgtgatggcg 11341 gcgctcgccg ggagcgtccc cgtgctcttc gcgggccgcg tcatccaggg cgtatccgga 11401 cccaccgtgc cgctctgcct gatcatgctg cgcaacgagg tccacgagcc gaagaagtac 11461 ggcaccctcc tcggcgtcat caccgccgtc aacggaggcg tcgccggtgt cgactccctc 11521 gcgggcggat acctcgccga ccaccatggc ttctcgtcca tcttctgggc catggccgcc 11581 gtcgccgcgc tcgccaccgt cctggtcgcc accctcaccc ccgagtcggt cgccaccgag 11641 tccgcgggag ctgagagccg tatggactgg cccggtgtcg ccctcctcgt cgtctccgtc 11701 ggagcggccc tgatcgccct gaacgaggcc gggaagctcg ccgacgccaa ctggccgctc 11761 gtcgccgccc tgttcgtcgt caccgccatc gccttcgccc tgttctggcg gaccgaggac 11821 cgcagcagcc accccctggt ggccacccac cacctcagtc agcgctccac ctgggccctg 11881 ctgctgacca ccgtgctcac catgaccggt gtgttcgccg tcatgaacgg cctgatcccc 11941 gccttcgccc aggacgccca ggcaggtttc ggcatgaccg ccgaacagtc cgcctggtgg 12001 accctgatcc cgtacgcgct cgcgggcctg gccatgggcc cgctcgccgg tcgcctcgcc 12061 gccacccacg gctacggccg catcctgcgc ctcggcctca tcggcgcggc cgccaccctc 12121 gccctgatgc tcctcaccct gcgagccgac tcccgcccgc tgctcctggc ggcgtcgatc 12181 ctcatcggca tcacctacgc gggcgtgggc aacatcgtcc tcaacggcct cggcatcgtc 12241 ctgtccccga aggagaaccc cggcttcctg ccgggcctga acgcgggcgc cttcaatctc 12301 ggcgcgggcc tcagcttcgc cctcgtctac gcggcgcaga ccgccgccga acccgcggac 12361 aagacgtcca ccaccggcta cggcgcgggc atcatcacgg gagccgcact catcgccgcc 12421 gccttcgtga cgtcgttcct catccccaag ccggtggagg ccgaagcgac gccgtgacgc 12481 tcacgacgcg ccatccgctc atggtgaagc gcggcgtgct cgccggtgcc ctgccggtca 12541 tctgggtgct gcggtggcgc ccaccgcgca tcctggaccg gatctacgcc tgggcttacg 12601 tcggtctgct caccgtggtg atggcggcga tggcgctgtc gggcgtctcg gggtgagcgt 12661 gtctggcagg ggcgacagcg ccgttgccga aatccgctcg gcagcgcaca gcggcacacg 12721 gcacagtggc cccatgagtg aacgagggct ggaccacgac ggaaccatcg cacgcgaagg 12781 cgcgctggac cgcgtgccga ccgcgttcgt ccccgtcgtc gatgccgccc gcgctcacat 12841 caccgggacg ttcggcggca cgcgcctgca cagcgcctac ctctacggca gcatcccccg 12901 tggcaccgcc acccccggcg tctccgacct cgacctccaa ctcgccctcc acgacgagcc 12961 caccgaggcc gaccgcgccg acgtcacagc gatcgagacc gcactcgacc gtgcgttccc 13021 gcagatcaac ggcgccggga tcctggtgag cagtgcgcgg ttcctgctca gcggcatcga 13081 acgtcacgac gccgggttct tcatcgcctg cctctgcacc ccgttgctgg gccccgacct 13141 cgcggaacaa ctgccccgtt accgccccac aagcctcctc gcccgggaga ccaacgggga 13201 cttcgcccgc ctgcttcccc actggcgggc gaaggcggcc gaagccgcca cggacgccga 13261 acgccggagc ttcgggcgcc gcgtcggccg gcgcaccgtc cgtaccggat tcaccctggt 13321 catgccccga tggggtggct ggaccagcga tctcgaccag tccgccgagc tgttcggccg 13381 ttactatccc gagcgcgccg agcagatgcg tgccgccgcg tccatgggcc gtacaccctc 13441 acccgacccg gcggtgctcg ggatgctcat cgacgacctc ggtccttggc tcgcggccga 13501 gtacaccgcc gtgcacggcg agagagcccc gcgtccctga acaggtctac gcatcacggc 13561 gcttcgtgct cgaccccggc catgaccgcg gtcacgacct tgcggacggc tccgggctcc 13621 ggcggggtgc cgtggcggtc ggcgaagagc atgtgcgcgg ccccgatcag ggtgggggcg 13681 agcgtgtcga cgtcggcatc cgcggtgatg cggccgcgtt cgcgctcggc ggtgaggtag 13741 gaggcgatcg cgatcgcggc ctcggtcagg atcggcacgc cggtgggcct gacctcgcgc 13801 agccgggagc gcaggtcgtc ccgggaggtc acgaggctga cgatggccac cgcgaccgcc 13861 ccgaacacgt ccatcagcgc ctgggtgagg ttgtccgcga cggtgccggt tccggcggac 13921 gcacgcaggg cggcggccag gtcgtcgatc cgggcgatgc ggtccagcac gagttcggcg 13981 aggaaggcgt cgaagtcggc gaagtgccgg tgcaggacgc ccttggcgca gcccgcctcc 14041 gtggtgaccg cccggctggt cagggcgctc ggcccgtccc ggagcaggat gcgctcggcg 14101 gcgtcgaaca gttggtcgcg cacatcgcgg atggctactc ccgtgggcac cgcgcaactc 14161 cttcttccct ttgacgagtg ggcatgtgcc ccactcatag gtgggcgcat gcccactttt 14221 accgccgggg cgagccccct cgccccgcac acacgactca tcgacaccga caggtggcgg 14281 agtccttcgg ttcggacgcc gaacgctacg accgggccag gccccgctac ccccaagccc 14341 tggtggaccg gatcgtcgcc gccggccccg gccctgacgt cctcgacgtc ggctgcggca 14401 ccggcatcgt ggcccggcag ttcgccgagg ccggttcccg ggtgctgggc gtcgaggtcg 14461 acgcccggat ggccgacctg gcgcgccggc gcggaatcga cgtcgaggtg gcgtccttcg 14521 aagactggga cccggccgac cggaggttcg acgccgtcgt gtccggacag acctggcact 14581 gggtggaccc gctcgccgga cccgccaagg cggcacaggc gctacgcccc cgtgggctgc 14641 tggccctgtt ctggaacgcg gcccagccct cgcccgaact gacggaagcc ttcaccgatg 14701 tctaccgccg cgtgatcccc gactcgatcg ccgtccgcca atgggcggtg cctgccgcgg 14761 aggggtacac cgcgctgtgc gcgcagacgg ccgaccggat gcgggaggtg ggcgcgttca 14821 ccgaccccga gcagtggcgg ttcgactggg aacagcccta cacgcgggac gagtggctgg 14881 accaactccc cacccagggc gccttcaccc ggctcccgca ggccgagctg gacgaggtgc 14941 tggcgggcgt cggcacggcc atcgacgccg cgggaggcag cttcacgatg cactacgcca 15001 ccgtggcggt cgccgcgacg cgaaccgatt ccgcctgacc gaggcgggtc ccttccgggc 15061 gaggggacac ggccgctggg cagacttacc ggcatggcga cctatgacac gctcggcgcg 15121 acatacgccc ggacccgacg acccgatccg cggatcgccg cgcagatcca cgccgcactc 15181 ggggacgtca cggatgtgat caacgtcggc gcgggcaccg gctcgtacga accgccgcgg 15241 acggtactcg cggtcgagcc cagccgcgtc atgctggccc agcgtccgtc cggatcggcg 15301 cccgcggtgc gggcggtcgc tgaacggctg ccgctgggcg acgatgccgc cgacgcggtc 15361 ttggcggtgc tgacggtcca ccactggacc gacctgacgg ccggaatcag ggaactgcgc 15421 cgggttgccc gccgccgcat cgtcgtcctg acgtgggacc agcgcatctt ccgcgaacgg 15481 ttctggctcg tacgggacta cctccccgag gccgccgcgt tcgacgacac ccgtgccgta 15541 cccaccgagc agttggccgc cctcctcggt ggcgcacgcc gggagccggt gctggtcccc 15601 catgactgct cggacgggtt cgccgccgcg tattggcggc gtccgcatgc ctacctcgac 15661 ccgcaggtgc gcgcggggat ctccctgctc gcgcagaccg gtgagaccgt caccgcaccc 15721 gggttggccc ggctcgcgga cgacgtggcg accggccgct ggcacctccg tcacgcggaa 15781 ctcctcgggc tcgaggccat cgacgtcggg taccggctac tggtgaccga cctctgacgc 15841 ggctcgcatg gggccggtga gggcgagggc gatgtcgtcg aggtcggggg tgtgcacggt 15901 gagggcctcg gcctcgatcg aggcgctgtc gagggtgtcc aggacggcgc ggagggcggg 15961 gatgccgccg tcggtgggga tgtacacggc gagcgcctcg tcgtcgcgcg tcaccgggcc 16021 gaaggcggtc atggccgctt cgagggagtg cgcgtcggcg aaccggagcc ggatgtgccc 16081 ggcgggcgtg ctgcctcccg gcgccttccc ggtgatgtcg gcgatggcca caggctcgtg 16141 tcggaggtag tcggcgtggg gggtgaagtc catgatgcca tcatgacgca tacgtggtgc 16201 caaagttaag ggtccgttcg ctcgtcagag gacccttgcg gaccataagc gcaggtggag 16261 ttgcgtgacg ccatgtgtgg cgccatgcgg tcaatcggcg acggcttggc gtccggtacg 16321 accgtggtgc cggaccgctc gtccggccgg agcccggcca gggcggcgtg gcggacgcgg 16381 ccgtcgagga cccgggccct gtcgaccccg tggcgcaccg cgtgcaggca ggccgccatc 16441 ttcggcgtca taccgtgcga caactccggg agcagcgcct ccagttccgt ggcggtcagg 16501 cgctcgatca cctcgtggct gtccggccag tccgcgtaga gcccctggac atcggtgagc 16561 aggagcagtt caccggcgcc cagggcggag gccagggccg cggccgcggt gtcggcgttg 16621 acgttgtaga tgccgtcgtc gtcggcgctg cgggcgatgg gggagaccac cggaatgcgg 16681 ccgtcggcga gcagcgtccg gagcagggtg gtgtccaccg cgctgatctc accgaccctg 16741 ccgatgtcca ccggtctgcc ctcgatcacc ggcaggtgcc gtacggcggt gacggtgtcc 16801 gcgtcctcgc ccgtcatgcc gaccgccagc gggccatggc ggttgatcag cccgaccagc 16861 tcgcgctgga cccggccggc cagcaccatc cggaccacgc ccatcgcgcg gggcgtggtg 16921 accctcaacc cgccccggaa cgttgccgtc agcccgtgcc gttccagctc ggcgctgatc 16981 tgcggaccgc cgccgtgcac cacgaccggc tggagcccgg cccggtgcat ccgtacgacg 17041 tcgtcggcga acgacgcctc cagctccccg tcgaccatgg cgttgccgcc cagtttgatg 17101 acggttaatc gatccttgcg cccggaggcg gcggagtgcc gggccggtaa agcctgtgct 17161 gctgaggcgg tcacgtgcgg ctcctccacg aggtggcggg aaatgcggcg ggccgaaaag 17221 tgcgggtggc gcggtgcgca ttattcttta tcgcaatgcc ggaacatacc gtgcgtccaa 17281 gattctgtcc cgccgacagg acaaccagac ccggttatcc gtttcctttt tcgccgctcg 17341 ggaaattcaa tggtagcgtc ccgggactga tgcacagacg tatctgtcca ttgccggaag 17401 gatgcctctc ggatgtttgt ccccagtcat taccgtgaac cggacagttc gtggatggtc 17461 gacatcatcc gcggaaatcc gctggccctg atgatgagca acggcgcggc gggcgagccc 17521 cccttcgcga cgcacctgcc ggtgataccg gaccccgcca tgaccggcga ctggtccgag 17581 cggctgtcgg aggcgaccct gctggggcac atgaaccggg acaaccccca gtggcaggcc 17641 ctggaggacg gcgcggtcgt ccgcatcgcc ttcagcggcc cgcacgcgta cgtctcgccg 17701 accctgtacg gggtgacacc ggcggccccg acctggaact tcacctcggt ccatgtgcgc 17761 ggggtcgtgg agcggattcc gtccaccgag gaaaccctgg aagtggtgaa atccaccgtg 17821 cgggctttcg aggccgattt cggtgagggc tgggacatgg ccgcatcgat cgactacttc 17881 cgcaagatcg tgcccggtgt cggggcattc cggatcatgg tgcggaacgt ggacgggatg 17941 ttcaagctca gccaggagca gcagccggag gtccgcgacc gggtgcggaa gtcgttcgcc 18001 gggcgggagt gcggccggca ccaggagacg gccgcgtaca tgagccgcct gccgtgacgg 18061 cccggagccc gcactgcgcc ggcagtgcgg gctccggacc gtgccgtccg gcgcggcgaa 18121 ggaggccgtc agccgctgat ctcctgcggc tcctccacga cctcctccag ggcccgttcg 18181 gcggccctgt cgagcgtggc gagcacccac tgttcgaggt cggtccccga gagctccgcg 18241 gccttgtgcc accactggag ccggttgccg ggcaccgcga gctgacgggt gggctcggtc 18301 gccctgccgt ggttgatgtc gtcctcgcgg gccagccgga gcgcgtggcg caactgcttg 18361 gtggtccacc ccatccattc tgctcgggcg cggtcgagcc attggttcct gctccctcga 18421 tcgagagcga ggccagttcc gcgtggtgct ggaacgtcag cgcggggcgg cggcggtgca 18481 gttcgaagcg ccgcgagacc catgcgtagt tccgcagcgt ctggtactgg agcccggcgg 18541 tgcggatacc gcgctggtag cggtcggtgt agtggtgctt gccgtagacc agccagtcgc 18601 ccagccacca ggaggaggag ttcacgatgc tggagagctg acgcccggcg cgttcccagt 18661 cgtcgaaggt caggcccacc gggatccgca gccccacgtt ggtcgtcagc acctggccac 18721 gcgtgtcggc gggccccgtt cttcgctgcc gttcggcgtc cggccgcttg ccgaacagga 18781 cgaccttggg gcggtcgaga tcgctggatt ggttcatcat cgtcctccgt atgcatgtgc 18841 gtccacgggg cgacggatcg cgtcgcgctc gcggacgagg agcggcttac gcgggtggcc 18901 gtcgaagggc atgcggctcc ggcgcgcagt ggtcgatgtc gcgcgcggtg atgtggaacc 18961 ggatgctcac ctgtcgcaga gtccgggcag aggcccgtgg gccgttcatc cgggtcaggc 19021 ggtgtccgaa tgcggtcgac ggctgtcaga aggagggcag gcgcggttgt atacgcgcgt 19081 catcgcccag cagtagccac tcgccccgta tgcctcgatc acaagtcccc ctacgcatgg 19141 cagtcacagc ccgcatccgg cgggcgtggt gagggtcccc cgaccccgtt tcaaggtggt 19201 atcagtagaa cccgcggctg cggaggattc aaggaaattg cggaacgccg agcgttaatt 19261 atcgagtggt gcggggcaat gctccgcgaa ctggtttaac gcgaaaatcg gaggattatg 19321 ttccgcaaca tttccccgac gggaagccgg acttcatgtg ctttggtccg gggaggtcta 19381 tttcacccag ccggtgtagt tctggctgac ttgcggggcc cgccgttcgc tgcggcggcc 19441 ggggtcctcg tggtgcagca tcgcggaggc cgcccgtacg agccaggcgt tgaccgagag 19501 cccctccctg ctcgcggcct cctcgatccg ggccttcagc tgctcgggcg gccggaagtt 19561 gacgcgcgcg gtggcgccat ccttggcgcc cggggcgcca ggcgcggccg gggcgtccgg 19621 cggggcgagc ggcggcgtgc cgttgaacgg ctgcgcgaag gggcgcgcgg actcgtccga 19681 gggctcctcg gacggcggga gcgtgaccac gaacccgggg tcgagccccc gcagccggac 19741 ctcgaccgcg cccggcgcca gctcgcgggt gatctcgtcc gcggcggccg acagggcgtc 19801 gagcaggacc agccgaacgc tggcggagag cggtgcgacg agacgctcgg cgacctcgcg 19861 ggtccgcgcg tcacccgcct cggcggcagt gatcagttcc tgccgcaggt cgtcgacgta 19921 ccgcatcagt tccatggtgt catcctcgcg ctgacgtggg gcgacctgca agtccgtccc 19981 ttcggggcgg cgcggcccgg ctacccccgc ggcaccggca cggcgtcccc gtccgccacg 20041 gcgtccgtgt gcaggccctc gaccagccgg atgaactccc cggccgtgga gtgcgcgtag 20101 aagtcgcgca gcggcacccc gggcagaccc ctctcgcgca gggtggtgag cacgtgcacc 20161 accaggagcg aattgccgcc gagctcgaag aagttgtcct cgtgggtcac cggcgtgcgg 20221 agggcctgtc cccatatctc caggatctcc cgggcgacgc cgtcggccgg tgccgtcccg 20281 gccgtcccag ccgcctcgtc cgtccgtccg ccgtctgcgc tggcccgccc ggcggcccgg 20341 tcgtggacgg cgggcggcgg gagctgtgcg acgtccggct tcccgttggg ggtgaggggg 20401 acggcgggga tcacggtgag cgtcgagggg accatgtagt cgggcaggat gcggcgggcg 20461 ttggcgagca gccggccggt gtcggcggcc gggccgtgcc gttcgtcgag gaccacgtac 20521 gcgtcgatcc ggctgctcgc ggaatcgccg ggcgtcgcct gtccggccac gacgacggcg 20581 gcgctcacgg ccgggtcgcc cgcgagcacg gaccggatct cgtccagttc gatgcggtag 20641 ccgcggatct tgacctggtt gtcgaggcgg ccgagatggt cgaggctgcc gtcggggtgc 20701 agccgcccct tgtccccgct gcggtagagg cgttcccccg tggcctcgtc cacgacgaac 20761 cgctgcgccg tcagctcggg ctgccccagg tagcggtccg ccaccccggc tccgccgaca 20821 tagatctccc cggccgcacc gggcggcagc acccggccct tggcgtcccg tacggacagg 20881 aaccagcccg gcagcgggcg tccgaccgaa cgggacccgg cgaccagctc ggccggggtg 20941 accgtctgcg cggtgacatg gacggtggtc tcggtgatgc cgaacatgtt caccgcacgg 21001 caccacgtcg gggagtggcg ggcgaaccac ggcgcgagca cccgcacgtc gagcggctcg 21061 ccgccgaaca ccaggagccg tacggacagt tcccggggcg tggtccggtc ggcgcgcacg 21121 agctgggcga aggcggacgg cgtctggttg agcaccgtca cccgccgttc ggccagcagc 21181 cggtggaact cgtcggtgtc acgggccgtc cagtacggga cgacgacgag ccggccgccg 21241 gtgagcagac agccccagat ctcccagacc gagaagtcga aggcgctgga gtggaagagg 21301 gtccagacat cgtcgggacc cagcccgaag tccgccgagg tggcggccag cagtgcggtc 21361 acgttccgat ggggcacgac cacgcccttc gggcggccgg tcgagcccga ggtgtagatc 21421 acgtaggcgg cctcgtcggg gctcgtgcgc cgcgcggcgg ccgccgcggg agtcctgccc 21481 agctcatcga cgcccaccac ccgtacgccc ggcgtcgcgg ggaaccgccc gggctcgccg 21541 atgaccaggg ggagccccgc gttctcggcg gtgtaccgca gccggtcctc ggggtggcgg 21601 tagtccatcg ggacgtaggc gcatccggcc ttgaggacgg cgaggagcgc cacgacgagg 21661 gaggcggtgc ggtccaggca gacaccgacc atggtgccgg gcgcgatgcc gagtccgtgc 21721 agaccggacg ccatcgcgtc ggcccgctca ttgagttgac ggtacgtcag ctcctcgtgc 21781 tcgtccacga gagcgacggc gtcggggcgc cgggaggcca cggcctcgaa gcgccggtcg 21841 atccgctcgc caccttcagg ctcgccgtcg cgctcggcgc ccccgagccg taacacctcc 21901 cgcgccgcct ccgcgggcag gaccggcagc gccgccagcg gggcgctgtc cccgccggcc 21961 gccagctggg cggccgcgtg ctcgacggac cggcagaacc actcggccac gcccggagcg 22021 atcacgccct cgtcgtacca ggccgcggcc tccaccgtgc cgtcgggccg ctccgcgcag 22081 tgcagggaga gggggaagac gggtgccagc gcgggcagcc gcgtccggcc gtccgccgcc 22141 gggtccgaca ccaccagacc gaccgcgggc ggctccggcg cggcctgttc gggtgcgccg 22201 ccgagccgcg ccagaaaacc ggccggggtc aggtcctcgt ccacggctac ggtgcgcact 22261 cgcgcaccct ccggggcgcc gggccgggtg tcgaggtgcc cgatctccgc ggtgggctcc 22321 ccctggtacc gggccgtggc cagggcggca gcgcccagca gttgatgtcc gctcagcgcg 22381 gcgcgcggca gggtgagcgg acgggccgag acgatgccgc gcgcggccgg gtccccgagc 22441 ccccagtcca ccggggtcca ccgcgcggcg ggcggcagcg cggacccggc gccggagtac 22501 ggtgcctccg gccccgccgc cgcgcccgtg accatgacgt cggccagccg ctccagcgcc 22561 gtacgcgtca cccggccccg tacccccacg aggacgagat gcgccgagcc gtcgccgtac 22621 gacagcaaca ccgcgcgcag cggggacagt tcggcccgca ccggccggag cgcctcccgg 22681 tgcagtcgct cccgggccgc cggagcgtca cccggcgcgg gtaccgcggt ttcgtgcagc 22741 cgcggttccg tggtgaggcc ccaccggcgg gccgcgtccg cgagccgtcg gcggagggtc 22801 ccggcgtcca ccggaccggg caggtccgcg atcagggcgt ggcagaagcg gccctgcccg 22861 gacaggtgcc gccgggaagg cagcacgggg tgtccggcgc cgggcggcgg cgcggcatcg 22921 ggcaccggcg cggcatcggg ccgggtccgg tggttcgggt gcgggggtgt tccggtgtgc 22981 gtcgccatga tccggtctcc tgccggtgtc ggagcggtct ggtgccgtcc ggtgtcggtg 23041 cggtctcgtg ccgttgccgc gcgcgggcgg tcacctgctg gtgaaacccc cgtcgacggt 23101 gatcaccgcg ccggtcacct gccgggagtc gtcccccgcg agccaggtgg ccgcgcccgc 23161 gatgtcggag gtctcgatca gcgtgttcat cggctggtcg cgcaggaaga gttcctcgta 23221 ctccccggcc gggacgtcga gcgagtgcgc gatctcggcg agcatgcgcc cctcgaccag 23281 cgggttgtcg cgtaccgaac ccgggcagag cgcgttcacc cggacccggt gcggggcgta 23341 gtccagcgcc gccgccttgg tcagcccgat gaggccgtgc ttggcggtga cgtagccgct 23401 gaagttgcgg tagccgacca gaccggcggt cgacgagacg ttgatgatgc tcccggaccg 23461 ctgcgcgacc atgaccggcg cgaccgcccg catcatccgc caggcgccgg tgaggtcgac 23521 gtccagcatc agcgaccagt cggactcgct gatctcgtgg agcaccagcc ccgacggggc 23581 cgcgatgccc gcgttgttga ccaggacgtc gacggtgtgg aagcgcccca gcgcctcctt 23641 gacggcagcg tccacctgcg ccgtgtcgcg cacgtccacc gccgccgcga ccacggcgct 23701 gccgcgccgc tcgcacagct ccgcggtgtg gcccagctgg ctccggctgc ccagcggata 23761 ccccaccgcg tccaggtccc cggcgatgtc gagcagcgcc agatcggcgc cctcgtccgc 23821 gaaccggacg gcgcactccc gtccgatgcc ccgggccgcg cccgtgatca cgacggtctt 23881 gccctgtagt gacgtgccca tgactccccg ctcgctcagc gctcggcgat ggtgcgcagc 23941 agtgcctcgg ccgcgtcggc cagatacatg tgcccgcccg gcagttcgac gtagcggaag 24001 gcgtccctgg tgacgtcgcg ccactgctgg gcgtgctccc gggagaccag ggcgtcggtc 24061 tcgccgcgga tcgaggtcac cggcaggccg agtggctcgt ccgacgacgg cttgtagttc 24121 tcgtgcatcg ccacgtccgc gcggagtacg ggcagcagca gctcccgcag atccgggttg 24181 tcgaacgccg cgtgccggta cccggcgaat tcctggacgc gctccaggaa ttcctcgtcg 24241 ttcaggccgg tcgcccggga gtcgcgcccg ttccacggcc cgggcgagcc gctcacatag 24301 agatgtgagg gacccgggtg gccgagccgt tgcaattccc tggcgatttc ataacacagc 24361 acggcaccca ggctgtgccc gaagagcccg aaagccggga attcggcggt gagctcggca 24421 atctgcggtg ccagctgagc ggcggcttcc agggcatcgg tgaagggcgt gtcgaggaac 24481 agctcctcgc gtccgggcag ctggaccgga atcaccttga ttccccggtc cggcccctcc 24541 gtccacgcac ggtagaagcc cgcaccactc ccggcgaagg gcaggcagac cagcggaaag 24601 ggctgtgacg gcatgattcc ccgttctttt tcgggcagtt gactgcggac ggcgcggcgg 24661 gtacgggacg tcccgggcgg ggcggccggt gtcccggcga caggacgccg ctggccgctc 24721 gggcgtaaag gaccgcggtc cctgtgccac cgtgccgatt tccggcgggt acgtggaaac 24781 tacgaaggga cgggcgccgc cgcaacaccg taaagccatt ccggtgtcct gtcgacggga 24841 catcgggaac gccttgtccc ggtgtcccgt tcactgcttg acccggccgc cccaagccgt 24901 gaaggtgtgg gggtcccggg cggtttggac gacacgcctc gaattcgccg acggtacgtc 24961 cggcgactat tcccgcccgg taattgaggc cgccggtgac agcgcgacgc gaaccgaatt 25021 cttccgatcc acttgtctgc atggggtgat ggatgtgcac gatccgttgg agcggtccct 25081 gccgctgacg gcggcggacg acacggccgg acggatcctc ggctcgacgg ttcccgcact 25141 gttcgcgcgg caggtccggc tggcgccgga cgccgtcgcc gtcgtctcgg gcgacgagga 25201 gctgacctac ggggagctgg acgccagggc cggccggctg gcccgcggcc tggtgcggcg 25261 cggcgtgggc ccggagtcgc tcgtcgccgt cgcgctgccc cgttccgcgg agtcggtcgt 25321 ggccctgctc gcggtgctga agtccggcgc ggcgtacctg ccgatggacc ccggctaccc 25381 cgccgagcgg gtcgggttca tgctgcgcga cgcccgcccg gccctgctgc tgaccgcgga 25441 cggcacggcg ccaggggacc cgggccgctg ccccgccgtg acaccggcgg aactggagga 25501 cgagggcgcc gccggagaac ccgacgacac cgccggagaa cccgacgaca ccgccggaga 25561 acccgacggc gcacggcata cggcggggct cgcctacgtg atctacacct ccggatcgac 25621 cggcaccccc aagggcatcg gggtgaccca ccgcgatgtg gtggccctcg ccacggaccg 25681 gaggtggcac ggcggcgccc atgaccgggt gctgctgcac tcaccgctgg cgttcgacgc 25741 gtccgtctac gagatctggg tcccgctcct gcgcggcggc cgcatcgtcg tggacccgtc 25801 caccgacctc acccccggtg tgctggcgga gctggtggcc cggcaccggg tcaccgcgct 25861 ctggctgacc agcgcgctct tcgacctcct ggtggaggag gacgtccgct gcctgaccgg 25921 cctccgggag gtgtgggtgg gcggcgaccg cgtctcgccc cgctccgtcc ggcgggccgt 25981 ggccgcctgc cccggcaccg tgttcgtgaa cggatacggg ccgacggaga ccaccgtctt 26041 cgccacgagc caccggatcg accccgacgc gaccggggac gccgaagtcc ccatcgggcg 26101 cccgctggac accctgcgcg cccatgtcct cgacgaccgg ctgcggcccg tcccgccgga 26161 cgccacgggc gagctgtacg tcgcgggcga cggagtggcg cgcggctatc tccaccgcgg 26221 ggccctgact gcggagcggt tcgtcgcctg ccccttcggc gctccgggcg agcggatgta 26281 ccgcaccggc gacctggtga ccaggaacgc ggacggcgac ctggtgtacc agggccgggc 26341 cgacacccag gtgaaggtgc gcggcttccg catcgaaccc ggcgagatcg aatcggcgct 26401 cctcacccac ccggccgtcg cacacgccgc cgtgattgtc cgtcaggacc gcggggcggg 26461 cacggcccgg cacctggtcg gctatgtggt gcccgcccgg gacgacgggc ccgcgcccgc 26521 ccgcacggcc ctgccggatg agctgcggga gcacgtggcg cggcgcctgc ccgagttcat 26581 ggtgccgtcc gcgttcgtcc tcctcgaccg gctgccgctg acccccaacg gcaagctgga 26641 ccgggccgcg ctgccggtgc cgcacctcac cggcgccgcg taccgggcac cgcggcccgg 26701 caccgaggag accctcgcgg gcatcttcac cgaggtcctc ggccgggccc gggtcggggc 26761 cgacgacgac ttcttcgccc tcggcggcga cagcatccag tccatccagc tggtgtcgcg 26821 ggccagggcg cagggcgtgg cggtcagctc gcggcagatc ttcgagcacc ggaccgtcgc 26881 ctcgctggcc cgggccgccg acaccgccgt cgaactcggc ccggcccccg tcctggccga 26941 gttcgacggc ggcggaacgg gccaccagcc gctgatgccg gtggcccggt ggatccagga 27001 gaccggcccc ggcttcgact cgctgctcca ggccgtggtc ctggaactgc cgcccggcat 27061 cgaccgggac gggctggccg cgaccctggc ggccgtggtc gaccgccacg atctgctgcg 27121 cgccacgctg cgggacgacg gactgttcgt cgggccgccg gggtccgtgg acgtacggcc 27181 gctgatccgc gacgtggcct gcgacggcca gtggtccggc gagccctggc gccacctgct 27241 cgtcaccgaa ctgcgcgccc tggccacccg gctggacccg gcggccggca ccgtggcgca 27301 gttcgtgtgg ttccggccgc cgtccgggcc gggccgactg ctggcgggcc tccaccacat 27361 ggtggtcgac ggggtgtcgt ggcggatcct catgccggac ctcgccgcgg cgtggaagca 27421 cgtacgggcc ggtaccgcac ccgggctgcc cgcgccggtg acctccgtac ggcgctgggc 27481 gcacgcgctg accgacgagg cgcgggccgc cgggcgggtg gccgaactcc cgcgctggac 27541 ctccatcgtc gacggacccg acccggtcct cgggacccgg cggctggacc cggcggtgga 27601 cgtgcagtcc accgtggaga aggtccgggt gctgctcccg gcaccggcga ccgaggccct 27661 gctgaccgcc gtccccgcgg ccttccacgg cggagtcaac gacgtcctgc tcgccggtct 27721 ggcgatggcc gtggcccggt ggcgccgggc caggggagtg gacgaaccct cgaccctgct 27781 gcggctggag ggccacggcc gggaggagga gtcggtgccc ggcgccgacc tgtcccggac 27841 cgtgggatgg ttcaccagcg tgttcccggt gcgcctggac ctgggcggga tcgacctcga 27901 cgaggcgttc accggcggcc cggccgccgg tgacgccgtc aaggcggtca aggagcagct 27961 gctcgccgtc cccggcaagg gacttggcta cgggctgctg cggtatctga acccggagac 28021 ggccgaggtg ttgcgcaccc gctcgatggg gcagatcggc ttcaactacc tgggccgctt 28081 ctcggccgcc gacatgcccg aggagctgcg gggcctcggc tggacccaga ccgcggaact 28141 cgccgagttc accgagctgg ccgaactgga cgccggacac gacccggcga tgcccgccct 28201 gtccgaggtg gacatcaacg cgacggtgac cgacaccccg gcgggccccc ggctcggcgc 28261 ggtgttcggc gcccccaccg gggtgctctc cccggcggag gtccgcgagc tggccgagct 28321 gtggcagcgg gcgctggaag cactggtccg gcacaccggc cgaccgggcg cgggcgggct 28381 gacgccctcc gacgtgccgc tggtctccgt cgcgcaggac gagctgacgg catgggagaa 28441 gcggcacccc ggcctggtcg acgtatggcc gctgaccccg ctccaggccg ggatgctcca 28501 ccacgcgcag ctggccgggg ccgacaccta ccaggtgcag ctgctcttcg ggttcgacgg 28561 cccggtcgac gcgcggcgga tgcgggcggc cggacaggcc ctgctcgacc ggcacccgag 28621 cctgcgcacc gcctatctgc ccgacgccgc gggggacacg gtccagctgg tggtgtcgga 28681 cgtggcgctg ccgtggcgcg agagggcgct gcccgaggcg gagttcgagc gcttcctcgc 28741 cgaggaccgc gccgtgccgt tcgacaccgc gacgcccccg ctgctgcgga tgacgctcgt 28801 ccgcgtcggg gcggaccgca ccgaactgct gctcaccgcg caccacgtcc tcttcgacgg 28861 atggtccgaa ccccttctcc tccgcgatct gctgtggctg tacgccgacc cggccgcact 28921 gcccgaggcc ccctccttcc gggacttcct cggcgtgctc gcacaccgcg accgggaacg 28981 gtcggtgcgg gcccacaccg acgcgctcga cggcatcgcg ggacccacgc tgctcgtccc 29041 ggaccggccc gacaccgacg tagaccacga cgctgtcggc tccggcttcg gcgaggtgga 29101 gctgccggtg acggccgacg aggcgagggc gctcgcgctc cgggccgccg agaccggcac 29161 cacgctcaac accgtcctcc aggcgtcctg ggcggtcgta ctcgccgaac tcaccggcag 29221 cccggacgtc ctgttcggca ccacggtctc ggggcgcccg cccgccctgg ccggggtgga 29281 caccaccgtc gggctgttca tcaacaccct cccggtccgg gcccggtgcg cacccgggaa 29341 gacgctcgcc gaggtcgcgg ccgagctaca ggccgcccag gccgccctgc tggagcacca 29401 cgactgcggg ctgacggaga tccacgaggc gaccgggttc ggcgcgctct tcgacaccct 29461 ggtcgtcttc cagtcgtatc ccttcgacag cgcgggcatc gccgaggcga gcggcgcggc 29521 cggactgccc gtgcccgcct tccgtaacat cgccggatcg cactatccgg tcgtcgtcat 29581 ggccgaccag gaccctgagc tgcggctgcg ccttcagtac acgaacggcg cactggaccg 29641 cgcggcggcg tccgccctcg gcgaccggct gctccgcgcg ctccgggcct tcctcgccga 29701 cccgcacggc cgggtcgggg cggtggacgt cctcaccccg caggagcgtc acctgcccgc 29761 cgtaccggca gcgcccgggg agtcggtccc ggagctgttc gcccgcctgg cggccgggga 29821 tccggacgcc gtggcgctcg acgtcgcggg ggcgacgacc ggccggggcg agctggaccg 29881 gcgggcggac cgcctcgcgg acgaactgct ccgcggcggt gtggttcccg gctccgtggt 29941 ggcggtctgc gcctccgatc ccgtggaccg ggtggtcgcc ctgctggccg tgatgcgggc 30001 gggcggctgc gccctgccca tggaccccga ggactccccg gcatggtcgg accgggtcct 30061 gcgccacgcg gaggcggtgg ccgtcgtgct cgacaaggag gccgacggcc tcccctgggg 30121 cgatctcccc cggatccggc tcgcccccgc caccgtggac tccggccccg ccgccccggg 30181 cacggcccgc ccccgccccg ggcacctcgc gctcatcgac tgcacggcgg acgcggcggg 30241 gcgtccgtac ggggtggtgg tcacgcgggc cggactggcg gccgggatcg gccggttcgc 30301 gccggacgcg cccgctgagg atgcgccgct ggtgaccggc ccggccaccc ccgcggccga 30361 cctgctgctc gccctgtgcg cgggccgcag ggtcgaggtc cgcgaggggg cgccggagac 30421 ccgaccggtc cacgcggacc cggcccgcgt ccgggtgctc agcccgtcgc tggccccggc 30481 cgcgccgggc gcggtgggcg agctgtacgt ggccggcgcg tacgggcacg gctgcgcggg 30541 tccgggtccg ggtccggtga ccgcggagcg cttcgtcgcg gacccctacg gcccggccgg 30601 atcccgtatg taccgcaccg gcgtacgcgg ccggatcacc gccgacggcc gggtggagga 30661 gaccgacggc agcggcggga cgggacggcg ggccgcggag acggtcctgc tgacccaccc 30721 gtccgtcgcg cacgccgcgg tcgtgccgtc cccgtccggc ggaggcgacg gcgacaccgg 30781 ctatgtcgtc gccaccgagg gcgcgcggat cgccctcgac gaactgcggg cctttacgcg 30841 ggcacggctg ccgcaccgcc tcgtcccccg ttcgctggtc gtgctggacg cgctgccgac 30901 gacggcgagc ggacggctcg acccccggcg gctgcccgac gtcgccggcg caccgcgccg 30961 cacggcgggc aacgcgcgcg aggagacgct gacccggctc ttcaccgaag tgctggggcg 31021 ggagcggatc ggcgtcgacg acgacttctt cgcactgggc ggaaactccc tgctcgcgac 31081 ccggctgatc ggccgcatcc gccatgaact cgccgtggag gtctccatcc gctcggtctt 31141 ccagcacgcc accatcgccg aactcgccgc gcactgggac gagatcacca cagcaagcgg 31201 tccccgcctg cgcaagagga gctagggaga acgtcacacc atgtccgtcc tgagcaccga 31261 actcgtcgcc gagaccccgt acgtctggcg cgccaggaag ccggggagcc gccatcggct 31321 gatctgcttc ccgcacgcgg gcgcgggcgc caccacctac gccgactggg cacccctgct 31381 gccgccggag atcgaactgg tcgccgtgca gctgccgggc cgccagaacc gcatcgccga 31441 gaagcccttc accgacgtcg ccccgctggt cggggtggtc gcccaggcgc tgcgccccgt 31501 cctcggcggc tcgttctcct tcttcggcca ctcctgcggc gcggcgctcg ccttcgaact 31561 ggcgaagacg ctgcgtacga agggtctgcc gggccccgcg cggctgttcc tgtccgcgca 31621 gcccgcgccc ggcgcgaccg gggtccgcca cctgcacgac ctgcccgagg acgcgttccg 31681 cgccgagatg atcgggctcg gcggcatcga cgaggagatc gcccgggacg agttcgtcat 31741 ggactccctc ctgccggtgc tccgcgcgga cttcaggctc tgggaacgcc accgcaccgc 31801 ccaggatccg ccgctggact gcccgatcac cgtcctggcg ggcgacggcg acccgcgcgc 31861 gcccaaggag accgtggacg ggtggcgtaa ccagacgaac gccgagttcg gcaccgtctt 31921 ctaccccggc gggcacttct acttcctcga ctcgcccggc gatgtgatcg cgctcatcgc 31981 cgagcagacc ctcggcgcgc cggagcggag gcccgcatga ccgtccacga tgccgaggga 32041 atcgacgccc tcgccgcggc cgtcctggag gtgcccggcg tccacgacgc cgtagccgtg 32101 gtgcgcaagg ccgtacgagg ggccgcgccc cggcccgcgg ccacaccgcc cgcacgggag 32161 ccggaacccg tggacgcgcc cccggccgac ctcgacggcg ggcccttcgc gatcccggag 32221 ggagccccca cgacgcttca ggaggccctg cgcgaggcgg cccggctggc gccggacaag 32281 gggacgatct acctcaccaa ggggcacgag gacgtgttcc agagctatcc cgcgctgctc 32341 gacgcggcgg agcgggtgct gacggggctg agggacgccg gtctgcggcc cggggacgcc 32401 gcgctgttcc agttcgacga caacaaggcg ttcctcaccg ccttctgggc ctgtgtgctc 32461 ggcggcttcg taccgacccc ggtcggcgtc gccacgacgt acgacgcacc gaacgagacc 32521 aaccgcaagc tgcacaacgc gtggaacctc ctcgggcgtc ccgtgctgct caccgacgac 32581 gccacggcgg acgcgctggc cggggtgcgc gcgctgtggg acgagccgga ggtgcgcatc 32641 ctgaccaccc ggcgccctcg ccgacggccc gcccgcccgc gactggttcg cggccacccc 32701 cgactccccg gtgctcaacc tgctcacctc gggcagcacc ggcgtcccca agtgcgtgca 32761 ccacacccac gcgagcatcg tggccaggtc gctgtccgtc gcccggcact gcgggctcac 32821 cggcgacgac gtcagcctca tctggatgcc cttcgaccac gtcacggtcg ccatgtacaa 32881 cgtgcgcgac gtgttcgtgc ggtgcctgca catcaacgcg aagatcgagc attcgctggg 32941 cgatccgctg ctgtggctgg actgggtcga ccgctaccgg gcgacgaacc tgtgggcgcc 33001 gaacttcgtc ttcgccatgg tcaacgagtg cgccgacgag atccgcacca agggctcatg 33061 ggacctgtcc tgtctgcgcg agatcaccaa cgccggtgag ccggtgatcg cctcgaccag 33121 ccaccggttc ctggaactgc tggcgccgca cgggctggcc gccgatgcca tgcgcccggt 33181 gtgggggatg tccgagacct gctccggggt cacctacgcc gcccagcacc tccacgaccg 33241 caccgcgggc accgtcgcca tcgacccgtc ctcgctcggc gggaccatcc gccacctcga 33301 ccccggtgac ccgcgcgccg tggtgctctc cacggtcggc cggcccatcc cgggggtccg 33361 gctgcgggtg gtggacgaca ccggccgggt gctgccggag ggccgcatgg gcgagctgcg 33421 catccgcggg ctgaccatga tgcacggcta cttcgccaac gaggaggcga accgcgcggc 33481 gtacgacgag gacggctggt tccgcaccgg ggacctggcg ttcgtgcacc acggcgagat 33541 cgtcatcgcg gggcgcaaga aggaccagat catcgtgcgc ggcgtcaact acatggcgca 33601 cgagatcgag agcgtcgtgg agcaggtcga gggggtgcgg gtcaccttca ccgccgccgc 33661 cgggctgcgc gaaccgggcg acgactccga ccggctcgtg gtcttcttcg tcccgctccg 33721 gtgggacccc gaggtgctcg acggtgtcac cgacgcgata cgcgccaccc tcgcccgcga 33781 ggccgggatc gcccccgatc tgctggtgcc cgtcaccgaa gccgagttcc ccaagaccgg 33841 gagcggaaag atccagcggg gggcgctcct ggacgggctg cgcgcgggcg cgttcgcggg 33901 ccggacgatc ggcgcggcgc ccgatgaggg cgaggacccc tgggtcttcc ggcggcagtg 33961 gaccgagatc cccgcggccc ccgacgcccc ggacgccgcc gggacgggcg tccggctggt 34021 catcgccgag gaggaggacc gggcgcggct gcgcgtcgac ggtccgctcg tcgccgtcga 34081 caggggaggg gagccgaccc ggcgggcgcc gggccactac gcggccagga cgcacgaccg 34141 cggggaactg cggcggatgc tcgcggccgt gaccgctgac cacggcccca tcggcacggt 34201 cgtcctcgcc ccgccgctgt ccggcggcgc cgacccccgc gcgcggctcg cggcggcgac 34261 cgcggagctg tccgccctcg tcggggcgct ggccgacggg gagttcggcc acccgctgct 34321 gctcctcgtc acggcgggcg cgcagtacgt acgcgacggg gacacggtcg acctcggcac 34381 ctgcgccctg cccgccctgg tacggaccgc cgcggccgag aatccgcggc tggtgatccg 34441 ccagctcgac ctgcccgccg aggccgacgc gtggcccgcg gccctgagcg ccgaactggc 34501 cgaccgggac cgcaccggcg tcgtcgccgt acgcgacgga cggcgcaggc agccgcgcct 34561 ggcaccggtc gagcgggacg gcgctgaccc cgcgccgccg ctgctcgcgg gcggtctcta 34621 cctggtcacc ggcggactgg gcgggatcgg gcacgacatc gccggctatc tcaccgccgc 34681 ctatggtgcg cggctgctgc ttgtcggccg gtcgcccgcc gacggggaga aggccgcccg 34741 gctggccgaa ctcaccgctc tcggcgaggt cgtgtaccgg cagctcgacg tcacggacgc 34801 cgccgcgctg gaggcggcgg tcacggacgc cgagacgcgg tggggccgcc cgctcgacgg 34861 ggcgctccac ctcgcgggag cggaccccac gggccagtgg gccgacctcg aacggcatac 34921 ggtggccaac gagtcggggg aggtcttcgc cgcccagtac ggggccaagg tggcgggcac 34981 cctcgccgtg gcggaggtgc tcgccacacg tcccgacgcc tcgctggtgc tcttcggctc 35041 cgtcaacgga gaattcggcg gccattcctt cggcgcgtat tccgcggcca atggattcct 35101 cgccggattc gccgaccact ggcaccacga acgccgcaga gccgtccact gcctcgcctg 35161 gagcatgtgg tccggaatcg gaatgaaccg cgatcagccc gccgcgcccg cccacagccg 35221 cggttttcgt tccatcgacg cgccggacgg tctgcggctg ttcctggagg cgatttccgt 35281 gccccaccac tatcaagtcg tgggcctcga cgcggcgaat cccgcggtca tggacgaatt 35341 ggtcccggaa cagctgcgga ccggcgaggt gctcgtcgcc tacaccgccg acgacatcga 35401 cccggagacc gtgcgcgccg ccgtcgcacc gagcacccgg gaccgtccgg tgccggtgcg 35461 cctggtccgg gtcgaccacc tgccgcggga cgccgcgggc cgggtcgaca ccgcccggct 35521 gctcgccgaa acggcggtcg gcaagcccgg acgccgtacc gtcacgcccc ccgcggacga 35581 cctggagcgc cgggtcgccg ccctctggtc cgaggcgctg aactgccccg aagtgggcag 35641 ggacgactcg ttcttcgacc tcggcggcaa ctccgtccgg gccacgcgcc tgctggcgct 35701 ggtcgacgac gccttcgcgg tccgggtccc gacacagcgg ctctacgaga acccgaccgt 35761 gcaggcgatg gcggccgtcg tcgccgaggc caccgcaccc tgaccgcccc gtacgtggac 35821 caaatcatgc caccaggaca tcggcccacg cccgggggct cgttcgcggt cctatccgct 35881 tgaccccgcg ccccacgggc cggaagtatt caccgtgaat tccgcggccc gcccgagagg 35941 aaatccgcgc gcggcgcgag gtgaaccgga aatacggctc acctgttccg agattcccga 36001 aaccccacga ccgtcgaacc gtcatgcgcc gtcgacgtcc gggtccgtac gtgttttcgg 36061 cccgtctgcg caggaagacc gatcgaggag tagacgcgaa atgatccctc tgtcctttgc 36121 gcagcgccgg ctgtggttca tcgaccgctt cgagggaccg tcggccacgt acaacatccc 36181 gttcgtactg cgcctggacg gagcactgga caccgcggcc ctgtcctccg ccctgcgcga 36241 cgtcgtcatc cgccacgaga gcctgcacac cctgttcgtc gaggacgccg acggcatgcc 36301 cgtgcagcag gtccggcccg ccgacgaggt gctgatggac gtaccggtcg tggacgtggc 36361 atccgagggc atcgacggtc tggtgatgga ggcggccgca caccggttcg acctctccac 36421 cgagatcccc gtgcgggcga cgctgctgcg cggcgggccc tcggaacacg tcctggtgct 36481 ggtcgtgcac cacgccgccg ccgacggcga gtcgatggtg ccgctcagcc gggacctggc 36541 caccgcctat gccgcgcggc tgcgcggcga ggcacccggg tggcccgaac tggcggtcca 36601 gtacggcgac tacaccctgt ggcagcggga actgctggga gagagtgacg accccgggag 36661 cctgctgtcc actcagctcg cctactggcg ggacgagctg gcgggcgcac cccagcagct 36721 gcggctgccc acggaccgcc cccgcccgtc ggaggccggc caccggggcg acgccgtcgt 36781 gttcaccgtc gaccgcgaac ttgtcgccgc cgtacaggag ttggcgcgct cccgggggct 36841 gaccctggcc atggcgatgc agtcggccct ggccgttctc ctgcaccacc tcggcggcgg 36901 cgaggacgtg accatcgggt ccaccatcgc gggacgcacc gacgaggcgc tgaacgacct 36961 ggtcggcttc ttcgtcaaca cctgggtgct gcgcacggac ctgtccggca accccacgct 37021 ggagcaggtg ctcgaccacg tccaggacaa ggcgctcagc gcctacgacc accaggccgt 37081 acccttcgag cggctggtcg aggccctgaa cccggagcgc tccaccgcct accacccctt 37141 cttccaggtg atgttcagct ggcagagcga ggccaggatc gacctcgacc ttccggggct 37201 caccgccacc ctggaggctg tccccacggg gacggccaag ttcgacctgg agttcaactt 37261 cgcggccgtc gaggacggtg tgcgctgcac cctcgaatac gcgacggacc tcttcgaccg 37321 gtccaccgcc gcggcagcgg gggagcgctt cgtccgcgta ctgcgccacc tcgtcgccga 37381 gccgggcgcg cggatcggcg cgatcgacgt gctgtcccgg gccgaacggg aactgctctc 37441 cggccgcaac gaaacagccg cccagctgcc cggggtgacc gtcccccagc tgttcgcgca 37501 gcaggccgcc cgcaccccgg acgcggtcgc ggtcacctcc ggcacccgcg agctgaccta 37561 ccgggacctg gacgagcggg ccgaccggct ggcgcgggag ctggtccggc gcggcatcgg 37621 cccggagtcg ctggtcgggc tcgcgctgcc gcgctccgcg gacctcgtga ccgccatgct 37681 gggcatcctc aagtccggcg cggcctacct gcccgtggac ccccgctacc cgagcgcacg 37741 cctcggcctc atcctctccg aggcccgccc cgggctgatc ctgaccgacg ccgagaccga 37801 ggcggtgctg cccgagggcg gcgccccccg gctcctcctc ggtgacgtgg acctggagca 37861 cgggacggcg gatgcccccg cggtcgccct gcgccccgac cacgccgcct acgtgatgta 37921 cacctccggc tccaccggca cccccaaggg cgtcgtgatc acccaccgcg gggtcgtcaa 37981 cggagtgacc cagctggcgt cggcgatcgg cctggccccc gggtcgcgga tgctggccgg 38041 tacctcggtc aacttcgatg tgtcggtctt cgagatcgtc accaccctga ccaccggggg 38101 caccgtcgag atcgcacgcg acgtgctggt cctgggggag cgggacggct ggtcgggcag 38161 tgtcatcagc accgttccgt cggtcttcgc cgaactggtc gacggcatcg cggaccgcac 38221 cgacgtcgag tgcgtggtgt tcgccggtga ggcgctgccc gcgtccctcg tccggcgggt 38281 ccgggacgcc ttcccgggcg tccgggtggt caacgcctac gggcagagcg agagcttcta 38341 cgccacgacg tacaccgccc ccgacggggc cacgccggac ggctcgggca gcgcgccgat 38401 cggtgccccg ctgggcaaca tgcggaccta tgtgctgggg ccgggcctga ccccggtacc 38461 gccgggcgtc gtgggggagc tgtacgtcgc gggcgaggtg ggccgcggct accacgaacg 38521 gcccggcctg accgccgggc ggttcgtcgc cgacccgttc gggaatcccg gggaccgcat 38581 gtaccgcacc ggcgacctcg cgcgctggaa ctccgaaggc cagctggagt tcgccgggcg 38641 cgacgacgcc cagatgaagg tcaggggctt ccggatcgag gcgggcgagg tcgaggcggc 38701 cctgaccgca cactccggag tggcacaggc cgtggtgacc acctacgacc ggcccggcgg 38761 caaacagctc gtcgggtacg tcgtctccac cggcgcgagc ggcggcagcg tcgagaacct 38821 cggcgagctg gaggtcgacc tgaccgccgg tgtctcggcg gccgagctgc gcgcgttcgt 38881 ctccgaacgg ctcccggagt tcatggtccc ctcggccttc gtgatgctgg accggctccc 38941 gctggccccc aacggaaagc tggaccacgc cgcgctgccc gccccggagt tcaccggggg 39001 cgactaccgg gcgccgcgca cggctgcgga aaagatcctg gcgggggtgt tctccgaggt 39061 gctgggcctg gagcgggtcg gcgtcgacga cgacttcttc gcggtcggcg gcgacagcat 39121 ccgctccatc caggtggtct cccgcgcccg ggcccgcggg atggacgtga gcccccggca 39181 gatcttccag agccgcacgg tggcggagct ggccgcggtg gtgggcgccg gcgccgatgg 39241 ggatgcgggc ggggtgctgg cggagctgga gggtggcggt gaggggtgga tgcctctgct 39301 gccggtctcg gagttcgtgc tgggccttgg tggcggtgtg ggccggttcg cgatgtcggc 39361 cgtggtggac gtcccggcgg aggtggacga ggccggtttg gtggccgtgt tgggtgcggt 39421 cgtggatcgg cacgatgtgt tgcggtcgcg gttggtgccg ggcggcttgg tcgtggggcc 39481 gcggggttcg gtggatgtgg cggggctggt ccggtgcgtg gcatcgggcg gtgacgtaca 39541 gcgggagctg gatgacgctg cggggttgct ggaccctgcg gcgggtgtga tggcgcggtt 39601 cgtatggctg atggacgagc gccaactgct ggtggtgctg caccacttgg tggtcgatgg 39661 ggtgtcgtgg cgggtgttgt tgccggatct ggcggaggcg tggcgtctca tccgtcaggg 39721 cgaagtggcg gagttggccg cgccggtgac atcggtgcgg cgctgggctc atgcgttggt 39781 ggaggaggcg ggccgtcggg agcgggtggc ggagctgggg gtgtggcgtt cggtggtcga 39841 gggcccggac ccgttactgg gctcgcgcgc cctggacccc gccgtcgacg tccagtccgc 39901 actggacagc ctgtgggtgc gattgcccga gacggtcacc cacgcgctcc tctccgacat 39961 ccccggcgcg ttccgcggag gtgtgaacga cggtctgctg accgggttgg cgcttgcggt 40021 ggccaggtgg cggcgagcgc gtggggtgga ggagtcctcg tcgctggtca ggctggaggg 40081 ccatggccgg gaagaaggtg tcgtccccgg ggcggatctg tcccggacgg tgggctggtt 40141 caccagcgtg ttccccgtac ggctggatgt ggcgggggtg gatgtcgagg aggcgttcgc 40201 cggtggtccg gcggccggtg tggcggtgaa ggcggtgaag gagcagcttc tgtcgatccc 40261 ggacaagggt cttggctatg gactgctgcg gtatctgaac gaggagacgg gcgcggagct 40321 ggcgccgtac tcgacggggc agatcgcctt caactacctg ggccgtttct cctcctccga 40381 catgcccgaa cacctccgcg gcctgggctg gactcgctcc ccgggcacgg aggggctgat 40441 gccgcggctg gacgacgaca tgcccgcgat ggccgccctc gacatcaacg cctatgtgac 40501 ggagggcgaa cggggacccc ggctgaccgc ccggttcggg ttcgcccccg gcgtactgtc 40561 ccccgaggac gtccaggagc tggcggacct gtggtgcgcg gcgctggagg ggctggccgg 40621 gcacgcgtcc cggccggacg ccggagggct gacgccttcg gacgtcccgc tggtgccggt 40681 gcggcagagc gagatcgacg gctgggagga gcggtatccg gggctacgcg acgtatggcc 40741 gctcaccgac ctccagtccg gcctgctctt ccacgcgctg ctggccggca ccacgttcga 40801 cgcctaccac atgcagatgg tgtaccacct ggccggacgc gtggaccccg accggctgca 40861 cgcggccggg caggcgctcc tggaccgcca cgccaatctg cgtaccgcct tcgtggcgaa 40921 caccaccggc gaacgtgtcc ctttcgtcat cgacggggtc caactgccct ggcgccacct 40981 cgacctgacc accgccgatg cacccgagcg cgacaggcac tccggccgct tcttggagga 41041 gagagcaagg acgaggactg atcactttcg aacccggccc ggcctccgct gctgcgcatg 41101 acgctgctga cgaccgcccc ccgacgctcc gaactcgtcc tcaccgccca ccacgtactg 41161 atcgacggct ggtccgtgcc gctgctcatg cgtgacctgc tgcgccttta cggggccggg 41221 ggcgaccccg ccgtactgcc cgcgagaccc ggctaccgcg acttcctggc ctggctgtca 41281 ggaggaccgt acggccgccg cccgcgcctg ggccgccgaa ctcgacggga tcgacgagcc 41341 cacgttcctc gcccctcacg ccgggacgcg gctccacacc gaggtgggcc aggtcggcgg 41401 tccccgtacc ggccgaactc gcccgcgccc tcgtccggcg cgccgcccac ctgggcatca 41461 ccctcaacac tctcgtgcag ggcggctggg ccctcctgct cattttttct tatcggacgg 41521 ccggacgtgg tgttcggcac caccgtctcc ggcaggccgc ccgccgtgcc cggcgtggac 41581 gagatggtcg gcatgttcat caacaccctg ccggtgcgcg ccgactgcgc ccccggcgcg 41641 accgtcgccg atctgctgac cgggctccag gagcggcagg cggtcctgct ggaccaccac 41701 cactacggac tggccgacat ccagcaggcc atcgggctgc cctcgctctt cgacaccgcc 41761 gtcgtcttcg agtcctatcc ggtcgaccgc gccgggatca gcgccgcgca cgacgaggcc 41821 gaggtcgcga tcaccggcat caccccgttc accggcagcc actacccgct ggtggtgacg 41881 gccgacgccg acccccatct gagggtggcg ctccagtacc accaccatgt cttcgaccac 41941 gagacggtga ccggattcgc cgcccgcttc gagcgggtgc tgcggcagct cgcggaggac 42001 cccgggctgc tggtcggcca ggtcgatgtg ctcgacccgg ccgaacggca gcagtggcgg 42061 gccgagtggc acgccgccac ccgccccgtc ccggccgtct ccttccccga actcgtgcgg 42121 gcgcaggccg ccgcgcgccc cgacgccatc gccgtcgagg acgaccggca gtggctcggc 42181 tacggggagc tggagcggcg cgccaaccag ctcgcccacc atctgcgcgg gctgggagcg 42241 ggccccgagc gggtcgtcgg gctgtgcgtc gaacggggag cggacctgat cgtcggcctg 42301 ctgggcatca tgaaggccgg tgccgcgtat gtgccgctgg accccggcta tccggcggac 42361 cggctggcgt tcatgctgcg cgactccggc gccggtctcg tggtggccga gcccggcacg 42421 cgctccgccc tgggcgccac cgacgccgtc gtcgtcgacc tcgccgagga cgcggaccgg 42481 atacggcagc agccggtgac cgtccccgag gacgggccgc gcgtcaccga cctcgcgtac 42541 gtcatctaca cctccggctc gaccggccgc cccaagggcg tcctcgtgac ccacgagggc 42601 atcgccaacc tggccgccga catggccgac cggctgcgca tcaccccgga cagccgggtc 42661 ctccagttcg cctccgccag cttcgacggc gccgtcatgg aggtgctgat ggcgctgccc 42721 aacggcgcca cgctcgtcct gccgccgcac ggccccgtca tcggggaggc cctccacggc 42781 ttcctccgcg agcggcgcat cacccacacc ctgctggtgc cctccctggt ggccaccctc 42841 gaccccgagg gtctggacac gttgcgcacc ctggtcgtgg gcgccgaggc ggcctcgggc 42901 gacctggtgg cccgctggtc agccgaccgc ctggtggtca acgcgtacgg gccgaccgag 42961 accaccatcg tggcgaccct cagcgaaccg ctgagcggct ccgccgtacc gcccatcggc 43021 agcccggtcg ccaacacccg cgtccatctg ctggaccatg ccctgcggcc ggtgcccccg 43081 ggcgtcgccg gcgacctgta catcgccgga ccgcatctgg cccgcggcta ccacggccgg 43141 acggcactga ccgcggagcg gttcaccgcc gacccgtacg gcgaattggg cagccggatg 43201 taccggtccg gcgatgtggc gcggcggcgc ggcgacggca cgctcgagta catcggccgc 43261 gccgacgatc aggtcaagat ccgcggcttc cgcatcgaac ccggcgagat cgaaggcgtg 43321 ctgggcggcc acccgaaggt ggcgcaggcc gtggtgaccg tccgggacac cggctccggc 43381 ggccgcctgc tggtggcgta cgtggtgccc gcggccgacg acaccggacg gctcaccgcg 43441 gaactccgtg agcacgccga ggccggtctg cccgcccata tggtcccgtc ggccttcgtg 43501 ctcctggacc gcctgccgac gaccgccagc ggcaagctgg accgggccgc cctgnnnnnn 43561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 43981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 44941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 45721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnt cagcccccgg 45781 cagatcttcg agtgccgcac ggtggcgggg ttggccgcgg tggtgggtgc tggcggggat 45841 gcgggcgggg cgctggcgga gctggagggt ggtggtgagg ggtggatgcc tctgctgccg 45901 gtctcggagt tcgtgctggg ccttggtggc ggtgtgggca ggtttgcgat gtcggcggtg 45961 gtggacgtcc cggcgggcgt ggatgagacg ggtttggtgg ccgtgttggg tgcggtcgtg 46021 gatcggcacg atgtgttgcg gtcgcggttg gtgccgggtg gcttggtcgt ggggccgcgg 46081 ggttcggtgg atgtggcggg gttggtccgg tgcgtggcat cgggtggcga tgtgcaggag 46141 gcgctggatg aggctgcggg gttgctcgat cctgcggcgg gtgtgatggc gcggttcgta 46201 tggctgatgg atgagcgcca actgctggtg gtgttgcacc acttggtggt cgatggggtg 46261 tcgtggcggg tgttgttgcc ggacctggcg gaggcgtggc gtctcatccg tcagggcgaa 46321 gtggcggagt tggcggcgcc ggtgacgtcg gtgcggcgct gggctcatgc gttggtggag 46381 gaggcgggcc gtcgggagcg ggtggcggag ctgggggtgt ggcgttcggt ggtcgagggc 46441 ccggacccgc tgctgggctc gcgcgccctg gacccggccg tcgacgtccg ctccacggtg 46501 gacacgttct ccgtacggct cccggcacag gtcaccgagg ccctgctgac gggcatcccc 46561 gccgccttcc ggagcggtgt gaacgacggt ctgctggccg gtttggcgct ggcggtggcc 46621 aggtggcggc gggcgcgtgg ggtggcggag tcctcgtcgc tggtgcggct ggagggccat 46681 ggccgggagg agggcgtggt tccgggggct gatctgtcgc ggacggtggg ctggttcacc 46741 agcgtgttcc ccgtacggct cgacgtggcg ggggtggatg tcgaggaggc gttcgccggt 46801 ggtccggcgg cgggcgtggc ggtgaaggcg gtgaaggaac agctcctggc gatcccggac 46861 aagggcctgg gctatggact gctgcggtat ctgaaccagg agacgggggc ggagctggcg 46921 ccgtactcga cggggcagat cgccttcaac tacctgggcc gtttctcctc ctccgatatg 46981 cccgaacacc tccgcggcct gggatggacc ccgtcccccg gtacggaggg gctgatgccg 47041 cggctggacg acgacatgcc cgcgatggcc gtcctcgaca tcaacgcgta cgtcaccgac 47101 accccgcgcg gccccgagct ggaggcacgg ttcgacttcc ccaccggact gctccccgag 47161 cacgaggcgc gggagctggc ggacctgtgg tgcgcggcgc tggaggggct ggcgacgcac 47221 gcgtcccgcc ctgacaccgg gggactgacg ccctcggacg ttccgctggt gccggtgcgg 47281 cagagcgaga tcgacggctg ggaggagcgg tatcccgggc tgcgcgacgt ctggccgctc 47341 accgacctcc agtccggcct gctcttccag tcccagctcg ccgacggcgg ccacgacgcc 47401 taccacatgc agatggtgta ccacctggcc ggacgcgtgg accccgaccg gctacgcgcc 47461 gccgggcagg cgctcctgga ccgccacgcc aatctgcgta ccgccttcgt ggcgaacacc 47521 accggcgaac gcgtccaact cgtcctcgac ggggttcaac tgccctggtg ccacctcgac 47581 ttgaccaccg cagacgtacc cgggcgcgac caggccctac gaaacttcct ggaccaggac 47641 cgggccgccc gcttcgaccc ggcccagccg cccctgctgc gcatggcgct cgtcctgacc 47701 ggcgaggcgg aagccgaact ggtcctcacc gcccaccacg cgctgttcga cggctggtcg 47761 ctgcccctgc tgacccagga cctgctgcgc ctgtacggct ccgggggcga ccccgccgta 47821 ctgccccgcg taccgggcta ccgcgacttc ctggcctggc tgtcccgccg ggaccgggcc 47881 gagtccgccc gggcgtgggc cgccgagctg gacgggatgg acgagcccac cctgctggct 47941 ccgggagcgg tggccgagac gggccagggg aacgtcggcc atatcgacgt gccgctggcg 48001 gacgacgtct cccaggagct gtcccggcgc gccgccgagc tgggcgtcac gctgaacacc 48061 gtcctccagg gcgcctgggg cctggtgctg gcagagctga cgggacgtca ggacgtggtg 48121 ttcggcacca ccgtctccgg caggccgccg gagctggcgg acgcggacgc gatggtcgga 48181 ctgttcatca acaccctgcc ggtccgcgtg gaggtgtccc cctgggacac cctcggctcc 48241 ctgctgaccg gactacagga ccggcaggcc gcgctgctgg accaccacca ctacgggctg 48301 gcggagatcc agcgggcggt cgggctgccc gccctcttcg acagcgtcat ggtcctggag 48361 tccttccccg tcgaccgcgc cgccatcgcc gaggcgaact ccgccgccgg gatctccgtc 48421 acccgcgtca gctcggacgg cggcacccac tacccgctcg gcgtggcggc caccgccgac 48481 ccgcatctgc gggtggcgct ccagtaccag cacgccctgt tcggccaggg cgcggccgag 48541 gacatcgccg agcggttcgg gcgggtcctg cggcagatcg ccgaggacat cgacgtgccc 48601 ctcggactgg tcggcacgct gccgcccgcc gagcgggaac ggctgctcgc cgaggcgggg 48661 gacaccgcgc tgcccgtgcc cggcggaacg atcgccgagc agttcgcgcg ccaggcggcg 48721 gcgacccccg acgcggtcgc ggtccacttc gaggacgtgc ggctgaccta ccgggaggtc 48781 gacacccgcg cgaacgcgct ggcgcacgag ctggtccgcc gccaggtggg ccccgggtcg 48841 gtcgtcgcgg tgtcggtacg gcgctcgccg gacctggtgg tggcgctgct ggccgtactg 48901 aaggcgggcg gggcctatct gccgatcgac tccaccttgc cggccgaccg catcgcctac 48961 atgggcacgg actccggggc ccgcctcgcc ctggccgacg ccaccaccga ggcggcgctc 49021 accgggctgc cgtgccccgt cctccgggtc gacgggatgg acggcgcgtt gcccgacaac 49081 gcccggcccg tcgcgtccgc cgcgcgcgtc gacgaccttg cctacgtcat ctacacctcc 49141 ggctccaccg gccgccccaa gggggtcgcc gtcacccacc gcgggatggc gagcctggtc 49201 gcctcgcatg tggagcggct ccacgtcacc ccggacagcc ggatgctcca gctcgtctcg 49261 ccgagcttcg acgtatcgct gtgcgaggtg ttcaccgcgc tgctgtcggg cgcgagcctg 49321 gtgctggccg acgccgagcg gctggtgccc gggccgccgc tggccgagac cgcggaccgg 49381 cacggggtga cccatctgat gctgaccccc acgatgctcg cggcgatgcc cgacgggtcg 49441 ttcggcagcg tcacctgcct ggtcatcggg ggcgaggtcg caccgccgga gctggtggcc 49501 gcgtggtcgc cagggcggcg catggtgaac gtctacgggc cgacggagat caccgtctgc 49561 gccaccatga gcctgcccct ggtggaggac ggcggcgccc gccccatcgg ccgacccatc 49621 gccaacaccc gggtgtacgt gctcgacggc gccctgcgac cggtaccggc cggagtggca 49681 ggcgagttgt acatcgcggg cccgggcctg gcccgcgcct atgtgggccg cccggacctg 49741 accgccgcgc gcttcgtcgc ctgcccgttc ggcggctccg gcgagcggat gtaccggacc 49801 ggtgacgtgg tcgcccgcac tcccgacggc gatctggtgt tcctcggccg gaccgacgaa 49861 caggtcaaga tccgtggctt ccgcatcgag ctgggcgaga tcgagtcggc cctgcgggcg 49921 caccccgcgg tgcggnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 49981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 50041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 50101 nnnnnnnnnn nnnnnnnnnn nnncggcggg ccctgcccgc cccggactac gcggtcacct 50161 cggccggtga cgccccgcgc accgcgcggg aggccatcct gtgcggtctg ttcgccgagg 50221 tgctgggggc cggtcaggtc ggcgtcaccg acagcttctt cgcgctcggc ggtcactccc 50281 tgctggtcaa ccggctcatc acccgcatcc gcgcggtgct gggcgtggag atcccgatcc 50341 gggtggtctt ccagtcgccc acggtcgcgg agctggccgc acacctggag tcggagaacg 50401 gcccggcggg cgacgcggac ccgttcgcgc cggtcctggc catcaccacc gagggggatc 50461 gggagccgct gtggtgggtc caccccggtg gcgggctgag ctggccgtac ctgggattcg 50521 ccggactgct tcccaaggac cgtccggtgt acggcatcca ggcgaagggg ttcgacggtt 50581 cggcaccgct gcccgggtcc atcgcggaga tggtcgccga ctacgtcgag gaggtgctgg 50641 ccgtccagcc ggagggcccg ttccacctga tggggctctc cagcggtggc accctggccc 50701 atgcgatggc cgccgaactc cagcggcgcg gacaccgggt ggcgctgctg gccctgctgg 50761 acagcgtgcc cagcggccgg ctggccgggc ggcccctgcc caccgaggcc gacttccggg 50821 actacttcgc cgaacacctc accagcctgg tgggcaccga ggactacgag tcgttcgtgg 50881 acaacgcggt cgcgatcggc gtcaactaca cccgtctgat gcgcgatttc accgcccccg 50941 tctaccgcgg cgacgccgtg ttcttcaacg cggtgccgaa accggagggg acgtacgcgg 51001 atctgtggcg cccgtacatc cacggcaccg tgcaccagca cgacatcgac agcgcccacg 51061 aggacatgta cctgccggga ccggcggccg agatctgcgc cgtcatcacc cacgaagtgg 51121 ccggggactg accggactcc aacgacgttc gtcggcggac ggaacggtcc ggcccccacg 51181 gaggaggcac ctttcaatgg ctcatgaaac ggaaatctac gatgtcgtcg gcatagggtt 51241 cggcccctcg aacctctcgc tggcgatcgc cctggaggag agtccggacc ccgtcacctc 51301 cctcttcttc gagcgtcagc ccacgctcgg ctggcaccgc ggcatgctgc tgccgtcggc 51361 caagatgcag gtgtcgttcc tgaaggacct ggccaccttc cgcaacccgg cgtccgggtt 51421 cggcttcatc tcgtatctgc acgacatggg ccggctcacc aggttcgtca acaaccagga 51481 cttcttcccg acccggcggg agttccacga ctacctcgaa tgggccgcgt cgaagctcac 51541 ggggcgggtc tcctacgact cggaggtcac cgcggtctcg gccgtcgccg cggcggggga 51601 ggggcccgcg gaccgggtgc gggtgacggt ccgcggtgcg gacggcgccc cgcgccaggt 51661 ggaggcgcgc aacgtcgtca tctccaccgg gctcgtcccc cggatgcccg tcaacctgga 51721 ggcgggcgaa cgcgtctggc acagctcgga gttcctgcac cggttccggc agcgggaggg 51781 cgagctgacc cgggtcgcgg tcgtcggcgc gggccagagc gccgccgaga tcgtccggtt 51841 cctgtacgac accctgccgg aggtcagggt ctcggcggtc atcccctcct tcggctacgc 51901 catcgcggac gacaccccgt tcgccaacca ggtcttcgac cccgacgccg tggacagcta 51961 ctaccacggg acgcaggcgt ccaaggacgc ggtgtggcag taccacaaga acaccaacta 52021 ctcggtggtg gacgacgagg tcatccgggg tctgtacgag cgcgcctacg aggacgagct 52081 gagcgggcac gggcggctgg acttccgcaa cctggcccgg gtgctcgacg ccgagcccac 52141 cggtgacggc acccggatca cggtctactc gctggtggac gacgcgtcgt acgacctcga 52201 cgtggacgtc ctgatctgcg cgaccggcta cgaccccatg aacccggccc gggtcctcgg 52261 cgagctggac aagtactgcg tgcacgacac ggaggggcgc caccgggtgg accgcgacta 52321 ccgcctggtc accacctccg acctgacctg cggcatctat ctccagggcg ggaccgagca 52381 cacccatgga ctggggtcgt cgctgctgtc gaacatcgcc gtccgcagcg gggacatcgc 52441 ccaatcgatc acggcccggt gcgcgggcgc accgaagaag ggactcaccg catgagcacc 52501 aacccgttcg acgacgagaa cggccgcttc tacgccctcg tcaacgagga gggccagcac 52561 tcgctgtggc ccgccttcgc ccccgtaccg gacggctggc ggatcgcctt cggcgaggac 52621 ggccgcaagg aatgcctcga gtacgtggaa gcgaactggg ccgatatgcg gccgcggagc 52681 ctgcgcgagt ccgtgacctc ggactgacga cgcgttgaag ggacgatcca tgaccactcc 52741 ggccgagcgg tggggcatcc acccggagca cttctggctg tacgggcgcc gaccgcgcca 52801 gatggtcgag ttcgacgaga agatgaacgc gtggaacgtc tacggctacg ccgaggccat 52861 cgaggtgctc ggcgacccgg ggacgttctc ctcgcacatg tcccgcctgc tgcccatggg 52921 ggccgacgag gcgttcacgg aaggggacct gctccagacc gacccaccgg accaccgcga 52981 actgcgcaag ctggtcagcc atgccttcac cccgaaggtc gtggccgaac tcgaaccccg 53041 gatcacggcg ctcacccagg aactgctgga cgcggtggcc gaccgggaca cgttcgacct 53101 gatgaccgcg ctcgcgtatc cgctgccggt gaccgtggtg gccgaactgc tgagcatccc 53161 gagcgccgac cgccatctct tcgagggatg gatgacggag atcgtgcaca gcctcggcga 53221 cgtctcgatg gaggacgcgc ccgaggacca ggagcggatc ttcgaggcgg gcatggcgcc 53281 catgcgcaag atgctcgaat acctccgcga gcatgcggcg gagtgccggc ggcggccccg 53341 cggagacctg atgggcaagc tcatcgaggc ggaggtcgac gggcggcggc tgaccgacaa 53401 ccacatcgtc aacttcgcga agatgctgct catcgccggg tatctgacca ccacgatgct 53461 catcggcaac acggtgctct gcctggacag ctacccggag caggcggcgc gggtccgggc 53521 cgaccggtcg ctcatcccgg ggctgctgga ggagtcgatg cggttcctga gcccggtggc 53581 ggccacctac cgggccacca cccgggacgt ggaggtcgcg gggcagcggc tgtcggccga 53641 ccagatggtc atggtgtggt tcggcgcggc gaaccgtgac gcccgccagt tcgccgagcc 53701 ggagctgttc gacatgaccc gcggccccaa tccgcacctc ggattcggcc gcggcatcca 53761 cttctgtctc ggcgggccgc tggcccggat ggagggcagg gtcgcgctcg accacctgct 53821 cgaccgcttc ccggagctgt acaccgatcc ggagcgtccg ccgaccttca tgccggggtt 53881 cgacacgacc ggggtcagca gcctcccgct gcgcacctcc ctcgggtagc gcaggagcgg 53941 aacgggacgt accgacgcat gggccactcg gggccatggc gatgccatcg tggcgcaatc 54001 gtcatggccc cgaattcttg ggcctgatcg cttcctgtcg agccttgccc gacgtgcctc 54061 catgcgaccc gggttgtcgt ggcgccatcg atgtgccact atggcgctat ggacatgacg 54121 ccctacaccg acggtctccg gcgcgagttc ctgctcgcgg ccgaggcggc cggcgaggag 54181 gccctcgggg tcgcggagcg actcgtcccg tcgctcgact cggcggtccg gctcaccctg 54241 ctcagcgccc tgtcgaccgc cgcgggcgag atctcgcgtg atctcgcgcc cggcgcggtc 54301 gacctgcggc tgcgcggtct cgacccccac ttcgcggtga ccctgccctg ggccgacccg 54361 gacgccgggg accatccggc gggggcgggc ggcgaggtgc ttccgggcgt cgaggacgag 54421 ggcgctccgg cgcgtatcaa cttccgtccg cccgagcacc tcaaggcccg gatcgaggag 54481 gccgcgggcc gcgaggggct ctcggtcaac gcctggcttg tccgggcggt ggccgccacg 54541 ctgagcggca cggcccggcc ggggcggcac acaccgccgg gggaccagta cagcgtcggc 54601 tgggtacggt agcgcgccgc gcatccgcaa gtggctcacc aggaaggctg acatggcaac 54661 gtacgacacc ccccaaccga tctccgccag ggtcgagatc tccacgggca ccatcacggt 54721 cagggcgagc cggcggaccg acacggtcgt cgaggtccgc ccgacggacg actccaacgc 54781 cgccgacgtc aaggcggcgg agcaggcgcg tgtcgacttc gcgcagggca agctccaggt 54841 caaggcgccc ccgcagatgc tgaactggcc cagcgcgtcg cgccgcaccg gctcggtcga 54901 cgtgctgatc gaacttcccg agggctccga tctgcgcggc agttcgtcct ccgtcgcgct 54961 gcgcggcgaa gggcggctgg gcgaatgccg tttcgaggcg gcgcacggcg acttccggat 55021 cgacgaggcc ggtccgctgc ggctgtccac gtcccggggt gagatcgccg tgacacgcgc 55081 ggtgggccac gccaggatcg ccaacggctc cgggggtgta cgcgtcgacg agatcgacgg 55141 gtccgccctg gtcggcaacg accacggcga gacccggatc ggcgacgcca ccggcgaact 55201 gcgcctgacc gggatgaacg gcgacttcca cgtggagcgg gcgcacggca acgtcgtggc 55261 caagaccgcc cacggcggca tccggctcgg cgaggtcgtg cggggctcgg tcgtggtgac 55321 ggcgtccagc gccgaaatcg agatcggcat ccggcagggc accgcggcca agctcgacgt 55381 gtccaccctg accggcaccg tccgcaacgc cctgaaggtc gtggacggtc cgggggagac 55441 cgacgagatc gtccacgtca aggtccgtac ctacagcggt gacatcgtca tccaccgttc 55501 ctgaaccgca tcgcccccgc aggcccgccc cggggaaacc cgtctacgaa tgagggaaat 55561 attgtgacaa cacatgaaag ggtcgtgctg gacgtcgaag gtctgcgcat gcgctacggc 55621 acgaccgagg tcctgaagga tgtgaatctc cgtgtgcacc acggggaagt ggtgtgcctg 55681 ctcgggccga acggggcggg gaagaccacc acgctggaga tcctggaggg cttccgcatg 55741 cgctcggccg gccgggtcga ggtgctgggc accgatccgg cgcacggcgg cgacgactgg 55801 cgggcccggg tgggcgtggt gctccagtcc tggcgcgacc acgggcgctg gcgggtgcgc 55861 gaactcctcg cccacttagg catctactac gccgagtact ccaccgccca gatccggcgg 55921 ccgtgggatc ccgacgaact cctcgccgcc gtcggtctga ccgcgcaggc ggacaagaag 55981 gtcaggatgc tctccggcgg ccagcggcgc aggctggacg tggccgtcgg catcgtcggc 56041 cgccccgaac tgctcttcct cgacgaaccc acggcgggtc tcgaccccgt cgcccggcgc 56101 gagttccatg acctcgtcga acgtctcgcc gacgagcagg acaccaccat cgtgctgacc 56161 acccacgatc tgcacgaggc gcagaagctc accaaccgca tcatgatcct cagcggtggc 56221 cgcatcatcg cggacggcac cgccgaggaa ctcgccgagc gcatcgtcgg cgaggacgag 56281 gtgcgctggt cccacgacgg ccagagctac gtccgttccg ttccggagtc cacgaaattc 56341 gccttcgaac tgttccggaa gcacggtgag tcgatcaccg atctggaaat ccggaagacc 56401 accctggagg atacctatct ctccctggtg cggcagtcca cgggcgaaca ggaaacagtg 56461 ccggaggacg ccgccggtgc ggcctcggcg gacagcgagg ggggcacggt ccgatgaaca 56521 agacggtcat gcgcgcgggc tggtcccgcg gtgtcacgga actgcgtcaa tcattcacaa 56581 atggcgggga cctcttcaac cacttcttct ggcccgtcct gatgctggtc gtgctgttcc 56641 tgatgcggga cgtctcgttc ggcgacggtg aattcgaact gggcaccctg gtgttgcccg 56701 gtatcctcgg aatgaacgcc gcgatggcca tggtcaccat gagccaactc ctcacggccg 56761 accgcgagga cggcacgctg ctgcgcgcca aggccacacc gcacggcacc cccgcctatc 56821 tggtcggaaa gatcatctcg gtgtccgtcg gcgtggtcgt cgacctcgcg atcttcctca 56881 tccccgcact gttcatcatc cccggtctgc gggtgggcag ttcggaggca tggctgaccc 56941 tgggctgggt gctggtgctc gggctggtgg ccaccctgcc catcggcgcg gtgctgggct 57001 cgctgttcag cagcacgcgc agccaggggc tgctgacgct cccgatcatg gcgatgatcg 57061 gcatctccgg catcttctat ccggtgacct ccatgcccga gtgggtgcag gggctggccc 57121 aggtgttccc ggtctactgg ctcggcctcg gcatgcgttc ggcactgctg ccggacagtg 57181 cggtcatcgt ggagatcggc gacgcctggc gccacctgga gacggtcggg gtgctgtcgg 57241 tctgggccgt ggtcggcctg gtcctcgcgc cgatcgtgct gcgccggatg gcgcggcggg 57301 aatccggctc gaccatggcc gagcgccgcg agaaggctct tcagcgggtc ggatgacgcg 57361 ccggtgcggt cccgtgggta acgggaccgc actctgcgga aaacataccg ttcccgcggg 57421 tcgccatgtc ctgtcgccag gacaggaaaa gcgcggtgcg gggggcgaac cttgacaccg 57481 taaggcggcg cttgaagact gggcgagcat gctgaattca ggccacaatt tccggaagga 57541 cacgcctgtg acctcgcccg tagcccagtg ggaattccat ccgggtcatt tctggatgcg 57601 tggaaagcgg ccggacaaga ttgtggacta cgacgaagag ctccagttat ggaatgtcta 57661 cggatatcct gagtcggccg cgatactcag caatccgaag gtcttctcca gcgatacgat 57721 gcggctggac ccgatcaagc tcgacgaggc gatcgtcgag ggcgacttcg ctcatacgga 57781 cccgccgaag caccgccggc tgcgcggtct cgtcgaccac gcgttcaccc cgtccctggt 57841 ggccaaaatg gagtcccgcg tccacgggat catccacgag ctgctcgacg gcgtcgaggg 57901 gaagagccag ttcgacctgg tggccgagtt cgcggcaccg ctcccgctga tcatgatctc 57961 ggatctgctg ggcgtaccgg agagcgaccg ggcgctgttc cggcagtgga tggacaagat 58021 gctcgacggc tcggagaagt tcgagtcccc ggagaccgtc ctggagcagg aggaggagct 58081 tcacaaggag ctcgaactgc tctgggagat gcgcgactac tggcacgagc gcgccgccga 58141 gagcaggaag cggccgcgtg aggatctgat cagccagctg gtgcacgccg aggtggacgg 58201 ccagaagctg aatgacagtc agatctccaa catcgccaac cgtctgctcg tcaacggcca 58261 cctcaccacg gcgatgctga tcgccaacac catgctctgc ctcgacgcct tctccgacca 58321 ggacgcacgg gtccgggccg accgctcgct cgtgcccgcg ctgctcgagg aatccatgcg 58381 ctacatgagc cccatctgcg gagtcgggcg ggcgaccaac agcgaggtgg aggtcgccgg 58441 cacggtcatc cccaaggatc agctgctgct cgtatggacc ggcgcggcca accgtgacga 58501 gcggcagttc gagaagccgg acgtgttcga tgcggggcga tcccccaacg cgcacctcgg 58561 tctgggccgc ggcatccatt tctgtctggg ccggcaactg gcccggatgg agagcaaggc 58621 ggcagtggaa atcctgctcg accgcctgcc caccctgcgt gcggacccgg cgaacccgcc 58681 gacgttcctc caggtggtgg atgccagcgg cgtcgccacc ctgcccgttg tcacccagta 58741 ggcccgttgt caccccgtag tccagcgata ccggcaagga gagatgcgat gacaacggtc 58801 gtcgaccggt ggaacatcca ccccgaccat ctgtggctgc gcggccagcg ccccgagtcc 58861 ccggtcgtct tcgacgagac ccagggcgtc tggaacgtct acggctatcc cgaggccatg 58921 gacatcctga acgatcacga caccttcacc tccgacctgg cgcacctgct gcccgtctcc 58981 gtcgacgcac cgctgctcga gggcgacatg tcgcagatgg acccgccccg ccaccgcaag 59041 taccgccagc tcgtcagccg ggccttcact ccgcggctgg tcgcggacat ggagacgcgg 59101 gtcgccgaca tcaccaggga gctgctcgac gcggtcgacg gcaagccgga gatcgagatc 59161 gccgccgatc tggcgtaccc gctgccggtc atcgtcatcg ccgaactgct cggcgtcccg 59221 gccggtgacc gcgacctgtt caagaagtgg gcggacgaca tcatcgaggg gttcagcggc 59281 ttctcgttcc tcgacacgag cgggcagggc gagcaggacg tccgcgacgc cacggagcgc 59341 ctgcgcccgt tgctcgacta catggccgga cacgtcaccg agcgccgccg caccccgcgc 59401 gaggacctgc tcacgcatct ggtccaggcc gaggtcgacg gtgaacgcct caccgacaac 59461 gagatcgtga acgtcgccaa catcctgctg gtcaccgggc acatcaccac gaccatgacc 59521 ctcggcaaca cggtcctgtg cctggacgcc gacccggagg tggccgcgaa ggtccgcgcg 59581 gaccggtcgc tggtgcccgg cgccatcgag gaggccctgc gggtgctctc cccgtccgcc 59641 gcgctcgccc gcggcaccag cagagaggtg gaggtcgcgg gcacggtcat ccccaaggac 59701 cagatcgtca tgctctggct gggcgcgggc aaccgggatc cgcggcagtt cacggacccc 59761 gaggtgtacg accccacccg cgaccccaac ccgcacttcg gtttcggccg cggcatccac 59821 ttctgcctcg gcgccccgct ggcccgcctc gaagggcgcg tcgcgctcaa cgccctgttc 59881 gaccgcttcc cggtgctgcg gaccgacccg gcgaagccgc cgaccttctt cccgacgccc 59941 gacatgatcg gcgtcaacac ccttcaccta cggacctctt gacccacccc accctttgag 60001 aggagacggc ttgtccgccg acgcgggggc agcggaagct gccccgacgg aacagtcgct 60061 gtcgcagatc gccctgggct tcgtaccggc gcgcatcctc tacagcgccg ccgagctggg 60121 catcgccgac gccctggcga acggcccgcg cgactacgag agcctcgcca aggagacggg 60181 cacggacccg ggggcgttgc gcagactgct cagggcgctc gccggactgg gcgtggtccg 60241 ccagctcgac accgatcgct tctcgctcac cgagttcggc ggccgcctga ggtcgggcac 60301 accggactcc gagcgggacg acatcatgct ctccaccgcg cccgaactct gggcagcatg 60361 gggcgagttg acggccgtgg tgcgcagcgg cgagcccgcc cgcgcccccg gcacgggccg 60421 cacggcctac gaggcgatgc aggagcagcc ggaggtgtcg gcgaagctcc gcgccggaat 60481 ggcccaggcg tcggcgctgt tcgccaccgg ggtcgccgag gcgtacgact tctcccggtt 60541 ccgtaccgtc gtcgactacg gcggcgacga gggcaccctg atcgcggcgg tcctgaccgc 60601 cgcgccggac ctgcgggccg tgctctacga ccggccggaa gccctggagc ggtcgaccgc 60661 cacgctgtcc gccgccggtg tcgccgaccg gtgcgaggtg gtcgaggggg acctcacctc 60721 gcccccgccg tccggcgcgg acgcctgcgt cctcaacaac atcgtgcgcg accggggcga 60781 cgagaaggcg acggagctgc tgcgctccct gcgcgccgga ctggcaccga cgggccgaat 60841 cctcctggtg gagaccctga tgccaccggt cctgacgccg gacgagtccg ccgcgtacgg 60901 actcacggac ctgaacaacc tggtcttcgc cggtggcagg gaacgcaccc gggacgagta 60961 cgccgcactg ctggccgccg ccggattcac cctcggcgcg acggtccggg tgcccgtgcc 61021 cacgggcatg cccgactacc acgtcatcga ggccgctccc acctcgtgac cgcggtcccc 61081 gcgctcaggt agcgagcgtg acctcgacca gctgggacca gcggacccgc gtcccctccc 61141 gggtcgcctc ggcgaaccgg acgtcgccga ggcggcgccg cgcggtccgc tcgatgcggg 61201 ccatgtccgg gtgggagcgg gtccggagcc cgcgtacgcc cgtgctcgcc gccagcagcc 61261 gtacggcctg ctcgtactcg tcgcggcgca gcgccaggtc cgcgaccccg atgagcacgt 61321 gcgcgatcag cggcgcgtgt cccgtctcgg acgccgccgc gcaggccgcc gcgcggtgcg 61381 cccgggcctc gccgaggtcg tcggcgaggt agccgagcag gtcgtgcgtc accgcgcgga 61441 tgtccgcctg ttccgcgtcg tcgcccaaca gggcagcggc gaccccgagt tgccggtgca 61501 cctcctcggt gtcgccgctc caccgggcga gtcccgcctt ggacagggcc agctcggcca 61561 gcgcgtccgg ccaggtgacc cgctccgcgc accgccctgc ctcggccatg gcggccgcgc 61621 tggcgtcctc gtcgcccagc agccagtaca gctgcgcctg ccacgaacgc atccggatga 61681 cgtcctcggt ggcaccgacc tcggtgacga ccgcgatcgc ctgctcgtag cgctcgcacg 61741 caccggcgaa ctcgccgcgc agggcgagca ggttcgccag ctcggacagg gcgagcgaga 61801 tcccgtaccg ctcgccgagc gcccggaact cggctagcgc cccctccagg tacgcgcccg 61861 catcgtggcc gtcctgcccg tcccggccga gcgcgatccg catcttgccc agatgccacc 61921 gggccagcgc gcgcacccag gggtcctcgt cgtccagcag cggttcgaac gcggacagcg 61981 acgactcggg cgcctggagc atgcgttcca gtacggccac gagcctcagc cccgggtggc 62041 tgcgccgacc gtgccgactg agccggtacg cctcgtggat ccactccgcg gcccggcgct 62101 cgtcgctcag ccctgaggtc acgaaacccg cgatcagcgc gcacaccgtg gcccggacct 62161 cgtcggccac ctcgccgggc agcccggcgg ccgcggtgag cagctcgatg ccctcggtcc 62221 tgcgcccgcc cagccaccag taccagcccc cgcccgccgc gagccgcatc gccgcccgcg 62281 cctcgcccgc cgcgagcgcg ccacgcatcg ccgcaccgag gttgtcgtgc tcggcctcga 62341 ccctggccag ccactccagt tgcccggcgc ggcgcagctg cggctccgcg gtctcggcga 62401 gttcggtgaa gtgggcgaga tgcgcgtggc gcgccaggtc cgcttccccc gcctccgcga 62461 gccgctgccc ggcgtactcc tggatcatgc cggtcaggcg gtagcgcggg gtgccgccgc 62521 cctcggcgag cagcagcgac ttctcggtca gcgcggtgag cagttcgagc acctgctccc 62581 gctcgacccc gtcaccggcg cagacccgct cggccgcctc caggctcgcc ccgcccgaga 62641 acaccgagag cctgcgcagg accatccgct cggcgtcggt gagcagctcc cagctccagt 62701 cgaccaccgc gcgcagtgtc ttgtgccgcg gcaacgccgt gcggctgccg cnnnnnnnnn 62761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 62821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngatggacat cgtgcgcagc cgtgccgcgg 62881 ccagttcgat cgccagcggc atcccgtcca gcgcccggca gacgcgcgcc atcgtcgtac 62941 ggtggccgac cgcgaggtca cggcgcaccg ccccggcccg gtcccgcagc aactggacgg 63001 cgggggagga ctcgatctcg tccgggctcg cgtccccctc cggcaggccc agcggctcga 63061 cctgccacag cgcctccccg gtgatgccga gcggctcccg gctcgtcgcc aggatccgca 63121 gccgccggca ctccccgagg acccggtggg cgaacaccgc cgcggcctcg atcacatgct 63181 cgcagttgtc caggatcagc agcgcgtccc gctcgcggat cgcggcgatg agccggtccg 63241 ccagctccgc cttcggggcc ccgcccagca gggtgtcccg caggcccagc ccggtgagcg 63301 ccgcctgcgc cacgtcgccg tccgcgccga tggcggcgag ctccaccagc cacgccccgt 63361 ccggcaggtc gccgagcagc gtgcgcgcgg tttccgtagc gagccgggtc ttgcccgaac 63421 cgcctggtcc gatcacggtg gtgagccggt gttcggcgat gagcccgcgg acggcggcga 63481 catcggcgcc cctgccgacg aaggtggtca gctcggcgcg cagattggtc ttacggctct 63541 cttcccgctg ccccggcccc tgcctcaact cgccccgcag cagcgcgata tgcagcgcgg 63601 ccagctccgg cgaggggccg acgcccagtg cgtcggccag ggcctccctc gtgcgctggt 63661 acaccagcag cgcctcgctg tcgcgaccgg ccgcggccag ggcgcgcatc agcgcggcga 63721 cgagcggttc ccgcagcgga tgcgcggcca ccaggtcggt cagctccgtg accatctccg 63781 ccccgtgccc gagggcgact tccgcgtccg cccgctcctc cgcggcggtc aggcgcagct 63841 cctggagccg ggcgaccgcg gcgtcgaacg cggcgctctc ccgcagaccg atgtcctgca 63901 tggccgcacc gcgccacagc ccgagggcct cgcccagcag ccgtgcgcgc cggggaggct 63961 cctcggtgcg ggaccggccc gcggtgacga ggcgttcgaa ccgtacggcg tcgacggcgt 64021 cgggctccac cgccagccgg tagccctctg tccgcccctc gacgaccgcg cccggcagcg 64081 ccttgcgcag ccgggacacc aggcgctgga gggcgttcgt cgcatcggcg ggcggatgct 64141 cgccccagat ccagtcgatg agcgacgcct tcgggacgac gtgacccggc ttgagcgcca 64201 gggcgaccag cagtccgcgc agccgcgcgc cggggacgtc ggccgagcca ccgtcgtcgg 64261 tacgcacctc gagtggaccc agcatcccga tctgcacccg ctgattttgc catggccgcc 64321 ttccacgcag ccggtagccg gaagttcagg cgaggatcga cagcaggagt gccattccca 64381 ggccgagcac gctgacgagt gtctgcaccg ccgtctgcgt cttcgccgcc tgggtgaggc 64441 tcatcccgaa cgactccttg accagccaga aaccggcgtg gttcacgtag ttgaggccga 64501 gggaaccggc gccgatggcc accacgagca gcgacgcctc caggccgcct ccggtgccga 64561 tcagcggagc gacgatgccg gtggcggaca cgatcccgac ggtggccgat ccggtcgtca 64621 gggacagcag cagggcgatc agccagccca gcacgatcac gttgacgtgg gcacccttgg 64681 ccgcggaggc gatggcatca ccgatgccgg agtcctggag gacctggttg aacgcgcccc 64741 cgccgccgat gatgagcagg atggtggcga cggacttgag gctgtcgttc agcgaggtgc 64801 gggtctcctc accggagcgg ccctggtgga cgagggtcac gccgagggcg aagagtaggc 64861 cgccgcccat cgccaccagc ggttcccccg cgaaggtgag ggcggcacgc agccggctgg 64921 actcgtcgag cgccgtctcg gcgacggcgc gcagcagcat gagcgcgacc ggaacgagca 64981 cggcggtgac ggccaggccc gtggggaccc cggcgcgggg ccgtatctcg tcgcgatgct 65041 gggcaccggg accggccgac gcgacggccg gggtcggctc gggcccggcg tgccgcccgg 65101 cgccggtgaa ctgggtgacc agcgtggcgt ccgggcgtac gtcagccagc cggggcgcga 65161 tccagcgggc gtagacgggc ccggccagga tcacggtggg gacggcgcag acgatgccga 65221 cggcgagggt caggccgagg tcggcatgga ggccggtcat ggcggtcagc gggccggggt 65281 ggggcgggag cataccgtgc agggtgcaca gcgcggcgat ggcgggcacc ccgagcagga 65341 cgtacggaga gccgttcgta ccgccccggt cctccagcct gcgcgccacg ctgaagatca 65401 gcggcaggag cacgatgagg ccgatctcga agaacatcgg aataccgatg acgaaggcgg 65461 cggccacgac gagccagggc aaccggcggg tgctggaccg gtcgacgatg gcgtgcgcga 65521 tggcgtcggt ggccccggag tcggacagca gacgtccgag catggcgccc agcgcgaggg 65581 tgagtcccac gtcgccgagg gtgcttccgg ctccttcctc gatggactcc gtcagcgtgg 65641 cgacgggttc gcccgccgcg agcccggtgc cgacggcgac gatgatgagc gcgacgaacg 65701 ggtggacgcg cagccgggag ttgatcagaa agatcaacgc ggagaacccc accatgaggg 65761 tgagcagcag aaaccaggtg tgggcggtca tgcgcggatt gcctttcgat gtctgaccgt 65821 tgagcgggcc ggcgcggcgc cggtgttcag gctccggtgg gctgggggac ctgctcgtcg 65881 tgcgcacgga gcgcggccgg gcggtcgagt tcccgatggg aggtctcggg gagcaggagg 65941 gcggccacga cggcgatgcc ataggccgtt ccggcgaaca ggccgatgct ggcgcccaca 66001 ccgatccggt cgctgaggta gccgacgagg gcggggaagg cggccgcgac gatacggccg 66061 aagttgtagc agaagctctg cccggtgccg cgcatggccg tgggatagag ctcggcgaag 66121 agcgagccga gaccggcggg aatgcccgcg gagaagaagc cgagagggat gccgaggaag 66181 aacatctgcg tctcggtgat cggtacgaag aggtagacga cgaccgagac caggcacatc 66241 gccgcgaaga agacgatgtt gcggcgacgg ccgatgcggt cggcgaggaa accggagacg 66301 acgtatccga agaaggcggc ggcgatgaac acggccagat aactgctggt cttgagcacg 66361 gacagatggt gctcggtgcg caggtacgtc ggcagaaagg tggtcagggc gtagtagccg 66421 ccgtggctgc cgaggccgag gaagccaccg agaagggtga cccgcagcag atcggtccgg 66481 aagatgcgca gcagcgagac ccggttcccg gacgtggcca cccgctgctg atagatcggc 66541 ggatcggtga ccttgcggcg gatgacgatg accaggacgg cgggcagcgc ggccagccag 66601 aacatcgaac gccaggccca ctgctcgggc agggcggtga acaggaaggt gtacgcggcc 66661 agtgcgaggc cccagcccac ggcccagccg ctctgcaccg cgcccagggc ccggccgcgg 66721 tggcgggtgc ccatgtactc gctgaccagg accgctccgg ccgcccactc accgccgaag 66781 ccgaatccct ggacgctgcg caacaccatg agctgggagt agccggtggt gaagccgatc 66841 agcacggtcg cggtggagta gacgaggacg gtccactgga gcacccggac ccggccgtac 66901 cggtccgagg cccacccggc gagccagccg ccgatcgccg tgcagatgag cgtgatcgag 66961 gcgagccttc cggcggctcc ggtgctcagc tgccaggcgg tcatcagggt gggcaggaca 67021 agaccgaaca gctgggcgtc ggccgcttcc agcgtccacc ccccgaacgc ggcccagaag 67081 gcccgtcgtt gtggcctgtc ggtgtcccgg taccaggcaa acatgagcgg ctcatttctc 67141 gtgcggggtg cccgcgccgg cgggggagtg tcagcgcagg tcgatgcggt agcggaaggt 67201 gcgggccagc ccgcgcgagc ggcggtattc cagcggagtg gcgtcatggg accgggcgac 67261 acggtcgatg acgacgacgg ggtcgtggcg cgcgcactgg agcagcaagg cgtcccccgc 67321 ggtggccacg tcgacggtga gttcctccgt ggcggccgcg acgatctgcc cgcaggtgcg 67381 ctcatagagg ggatagagaa ggtcgcccag gtcgtcctgg ccgatgcgct ccatcggttc 67441 gaacagcggg agcggcagcc agatgtcctc gaccaggacc ggcttctcct cgtacagccg 67501 cagccggtgc agatgcagca cctcgctccc ggcttccagg cccagggcgg aggtgatggt 67561 ctgcgtgccc acctggcggg cgatggagag gatgcggctc tgcgggaagc cgtcccccgc 67621 ggtgccgaac cggaagaacc ggaagaggga ggccgtcagg gaggcgcgcc ggacgaacgt 67681 gcccgacccc tgccgtcgct ccagcagccc ttcctcgacc aggtcgcgga aggcccgcct 67741 gatggtgccc agggacacgt cgtagtacgc gaccagagtg gactcggccg gaaggggctg 67801 atccggggcc cattccccgg cccggacgcg ttccgcgatc acttcacgga ggcgggcgtg 67861 caggggaagc cggggatccg tcctggcaag ggcggcctga cctgggctca cggcatcgtc 67921 aggggcgggc gacatcggct gcatgcccca caccctgccc ctgtttccta cagacgtcta 67981 gtccttcata gggaaaattc ttctgaggtg acttcgacca agcctgcacg cgcccccgac 68041 ggagctgtcg atacgcacgc ccatgtctcc ccgagcgatg agattcgccc ccactcgtcg 68101 ctacaccccg gactacgacg ccaccccgga cacttacctg tcgctcctgg acacccatgg 68161 gctggacggt ggggtgctgg tgcagccgag cttcctcggc accgacaact cgtatctgct 68221 ggaagccctg ggcaaggccc cccaccggct gtggggtgtc gccgtgatcg accccgggac 68281 ctcccgggac gagctggacc ggctggtgcg ggcgggcgtg tgcggcattc gcctcaatct 68341 ggtcggacgc ccggtcccgc ctctccatga ggccgtatgg cagcgcctcg gccgcgcgct 68401 cgcggcacgg aacctgcacc tggaagtcca ggcccgcgcg gagcagtgga acgagctgtc 68461 gccgtggctg ctccgctggc ccggacaggt ggtcgtcgac cacctgggcc ttcctctcga 68521 cacgaccctt tcctctcccg gggcgaaggc gctcgtctcg ctgctgacgg ccgatcatgt 68581 gtgggtgaag gcgtccgcgc cctaccgatc ggcccgcgcc gcggcgtcgg ccatgctgca 68641 ccacgtgctc gatacggccg gcccggccag gaccctatgg ggcagcgact ggccgtggac 68701 ccagcatgag gagggcagga cctacgccga cacgttgtcc tggctcatgc gacagctcag 68761 cgccacggag atcacccagg tgttgtgcgc caacccgctg aggctgctca ccggagggcg 68821 ggccggtgat ctggccgcgc cggtcggggg atcggtatcc cggcgttctt cgcggaagct 68881 gcgcggatga tttatcggcg cccacaagat ccctcaggag atcgtgccgc gagggttaac 68941 taagtgttcc cctacttctg ggagaggtaa gctatgtgct ttgtatttgc tgacgctccg 69001 ggaggtaata tcgggcgcaa cggccgtggc tgaattttcg ctattgactc gattcacttc 69061 ccggtatccg ggagttcatc tatggaatcc acgcctcttc gaacggcttc gccttggcta 69121 ttgggcctgg tgagagcggt tgtgtggccg gaaaccgatt cgcgtgtttt ttatcttaaa 69181 atgcgttccg gtggtcatga tcggccacgt tagttgacac atgtacttgg cagtcgtaac 69241 gtcccttggt aaggggaatg aagtgaatgc ctgcccatgc aggcctctga taaagcattg 69301 cactatatgc aacggcaggg ggagctggat ggggtattcc aagggaaaaa gtgtgcaggt 69361 tctcggtatg ttgcgtattg ccgacgacgg tgaggtggag agtctggcgt tggcccataa 69421 gcctcgcacc gtactggcga tgttggtggc tcaccccgat caggttgtgt cgctgcccgc 69481 actcgttcgt gaattatggg gtgatcaccc tccggccagt gctctcaggg tcgtccagac 69541 ctacatcctc caggcacgga aggcgctcag tcaggccacc cggcttccca tcaaggtcat 69601 catccaagag gccctcacga cgcatgccgg tggctacatg ttcagtgagt cgttcgcccg 69661 actcgactac cggatctatc aagggcttgt cgactcgggg cgcaaagcgc tggccaatgg 69721 tgatctttct gccggggtca gctatctggg tgacgctctg gggatctggc gagggtcggc 69781 gttcgctgat gtcgtcgtcg gaaggatgct ggaatcccgc cggcggcagt acgaggagtc 69841 ccggttgggg gcgttggaga cgctcgccga agcgaagatc gagattgggc gccacttgga 69901 ggtcaccgcc gacctcgccg cccttaccac cgagtatccc tatcatgagg ggttgcactc 69961 ccaatatatg cgcgccttgg agaaggccgg gcgccgggcg caggcactcg aagtgttcca 70021 tcgcctgcgc gtcgggctcg tgtccgagct gggtatcgag cccggccata cgattagccg 70081 tctgcaatac agcattctca actcctctcc ggtcaacggc gtctgacgtg cccctatggg 70141 cacggttcat tgatcgtccc tcggtccggc tcctttacgc gacggtgtat ccgccgtcca 70201 cggcgaagat ggctcctgtc gcataactgg ccagggggtc cgtgaagttc aggatccacc 70261 aagcgatctc ctcggccgtg cccaaccggc ccatcggtat ctgctcctgg gtctggtgga 70321 tggtcatcac tgcttggtcg tcaagcgcgt tgttctccag gatcggcgtc tcgatcggcc 70381 ccggagccac ggaaaccacc cggacgcagc tctgggccaa ttcgtttgcc caggagcggg 70441 tgaagaagtc gagcgccgcc ttggtggcgc catatacgca taagcccggc caaccgtgct 70501 ggccgatggc cgcgctgatg ttcaccacgg tcccttccgc acgctccagg cagggcagtg 70561 cggcctgggt gatcagcagc ggggcccgga gattcacggc gatgaattgg tcgaactccg 70621 atggagtgat catgccaagg tgcgttggcc ggaagacgct ggcgctgttg accaggatgt 70681 cgatgccacc gaaggccgcc actgcctccg agatgatcgc ctgaggggcg tccacctcgc 70741 tgatgtccgc ggtcaccggt gtgatcgacg gccgcccctt cgcggtggcc ttgagctttt 70801 cgagtgtcct tcccacggcc agcacattcg ccccgtggtc agcgaaagcg cgcgccgtgg 70861 cgcgaccgat cccgctgccg gcccccgtga tgacgatggt cttgccggtt aaggtggact 70921 ccatcgaaaa gctctccctg gctgcctcgg cgatgtgctg tacacactat gaacaccgta 70981 tgcgcccagg gagttgcaca ccgttaaggg cggctttgtg cggaagtgcc ccgcggagcg 71041 cgctcgtcag cccacgggat gaccatcccg ctcgaagtgc cgcaccaggg tgcggtcggc 71101 gagcaggatc tggtcgagac cgcgagtgag cgcacgtcgg tcggccagcg ggtcgaaacg 71161 gccgaggacc cgcagcgctc cgctcggatc ctgctccacc aggtcacggg tccgcagcca 71221 gccggccagg gtgtgctcac catcgggaag gaagcggccg ggaggccccg cctgcggcag 71281 atacggcgaa cggtcgaggc gcacctgcaa ctccccgtcc accagccgca gctggaggcc 71341 gggcaccggc atcccgacgg tgtcgggccc gtaccagccg gtggggtccg tggcgatgat 71401 cccggtttcc gtggtgccgt aggcctgccc gatccgcacc cgatgacgct cggcgaagcg 71461 ggtgtacacc cggtgggcca tctgctcacc gccggagatc gccagccgta gccgagggat 71521 ccgcacggga cggtcgatct gggcgagagc ggcgaagtgc tggggggacc cgatgatggt 71581 gtcggccccc gaccggatcg ccgtacgcag cacggtgcgg cggcccgagt ggggagccag 71641 caggaccgtg ctccgggtgc tcgtcgcgta cagcacgccg ccgaccaggc tgaaggagtg 71701 cgcgagcgga ccgaggacca ggacccggga ccttggctcg ggcataccgc cgacggtctt 71761 gaaccgctcc agctcggtca gcagcgactc gggtgtgcgg ccgatggcct tggcgaaccc 71821 ggtgctcccg gaggtgaact ggaccaggca gtgatcggtg gcggcggggc ggcctctcag 71881 gaggcggcgg acgaagacct cgcactcgtc gtggaaggtc tcctggccgt ggcccggcgc 71941 gtcgaaggag acatggaact ggggccggca ccagtccagc tggcggccca gctccttgcc 72001 gcgcacatgc gggcccatga gcatgacctg ggcgccgcag gaccacaggg cgaacagggc 72061 ccatagctga ctgaagctat gggcaccctg gagggcgacg gtgtgtccgg aacggatccc 72121 ataggcatcg aagagccgcc gcatctgggc gacttgggta cgcaacgttt gataggtgac 72181 gccgtgcccg gcctgggccc agagggcgct gcccggtggt gcgcccagca gatcggcacc 72241 ccaccagtcg ggctccgggt ccacatatgc agccatgacg ggttcccctt cccgctccac 72301 cgctcggcgc cggagaggac ctcatgcgcc gtctctggga aaacaccgga cagccgccga 72361 aggttgcatc ggaggtgcgt cggagtcgcg tcggagttgc agaggagggg aaccggtgcg 72421 cggcggaaag cgatcggcga ccgcgaatct ccccgtcagg cggccgcttc cgtcgcgagc 72481 aggtagcgct tggcg //