LOCUS NZ_GG657754 58717 bp DNA linear CON 01-MAY-2024 DEFINITION Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome shotgun sequence. ACCESSION NZ_GG657754 VERSION NZ_GG657754.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces himastatinicus ATCC 53653 ORGANISM Streptomyces himastatinicus ATCC 53653 Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group. REFERENCE 1 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D., Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Annotation of Streptomyces hygroscopicus strain ATCC 53653 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA REFERENCE 3 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Arachne v. April 2007 Genome Coverage :: 6x Sequencing Technology :: ABI ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_000158915.1-RS_2024_05_01 Annotation Date :: 05/01/2024 03:02:38 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.7 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 9,680 CDSs (total) :: 9,608 Genes (coding) :: 8,720 CDSs (with protein) :: 8,720 Genes (RNA) :: 72 rRNAs :: 4, 1 (5S, 16S) complete rRNAs :: 4, 1 (5S, 16S) tRNAs :: 64 ncRNAs :: 3 Pseudo Genes (total) :: 888 CDSs (without protein) :: 888 Pseudo Genes (ambiguous residues) :: 0 of 888 Pseudo Genes (frameshifted) :: 423 of 888 Pseudo Genes (incomplete) :: 530 of 888 Pseudo Genes (internal stop) :: 36 of 888 Pseudo Genes (multiple problems) :: 97 of 888 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 20:01:42 NOTE :: This is a single region extracted from a larger record! Orig. start :: 8919629 Orig. end :: >8978346 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to GG657754.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation was added to the scaffolds in August 2010. FEATURES Location/Qualifiers region 1..>58717 /candidate_cluster_numbers="1" /contig_edge="False" /product="T1PKS" /region_number="33" /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /tool="antismash" cand_cluster 1..>58717 /SMILES="CC(=O)C(C)=CC(=O)O" /candidate_cluster_number="1" /contig_edge="False" /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /kind="single" /product="T1PKS" /protoclusters="1" /tool="antismash" protocluster 1..>58717 /aStool="rule-based-clusters" /category="PKS" /contig_edge="False" /core_location="[20000:>38717](+)" /cutoff="20000" /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /neighbourhood="20000" /product="T1PKS" /protocluster_number="1" /tool="antismash" proto_core 20001..>38717 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))" /neighbourhood="20000" /product="T1PKS" /protocluster_number="1" gene 269..1258 /locus_tag="SSOG_RS38070" /old_locus_tag="SSOG_07551" CDS 269..1258 /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1067: putative ABC transporter permease protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009719635.1" /locus_tag="SSOG_RS38070" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07551" /product="sugar ABC transporter permease" /protein_id="WP_009719635.1" /transl_table=11 /translation="MKTVEPAPAAPSRREQGPPVNPVKRARPVRTNRDWAHGLLMSAPA VAGLIAFVGIPFGYAVVLSFYNVRLGSPLEPTFFGIEQYRRLFTDPDLSGPFLRALLNN LTFAVVVVPLQTGLALGLAILLNRKLKGIGLFRSLFFMPVVFPMALVAVIWRLILARSD EGLLNSALHAVSFGNWGAFDWLGDGATAMASIIVLSVWQGVGFQMVILLAGLQQIPGEL YEAAELDRAPRWQQFRHVTLPGIRGTLVFVAMLTSVLSFRVFDQVYVLIHGGGLDEDAT RTVMYQAVTTAFDQNNIGQASAITVVFFLIVVALTLIQRRLVRPDNED" gene 1265..2107 /locus_tag="SSOG_RS38075" /old_locus_tag="SSOG_07552" CDS 1265..2107 /GO_process="GO:0008643 - carbohydrate transport [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1069: putative ABC transporter permease protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003994489.1" /locus_tag="SSOG_RS38075" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07552" /product="carbohydrate ABC transporter permease" /protein_id="WP_009719636.1" /transl_table=11 /translation="MATTRAPLRRFADYAVLGILAFIFVLPVLYLLLGSLKPSDEVLNG LTGFLPTHLSFDNYAAVLDALNSDSTGYFWRFMGISLLVAFVVVTGGLFVNSMAAYGMS RLKWRGREAVFTLVLLLMLVPFESVAVPLFYMFNDQRDTIFIQAVPFIANAFSIYQFHT FFRSIPPSIEEAARLDGAGPWRTFFAVIVPMSKPVFASVAILTFLMQWGSFLWPVLMVS DPSVRPLPLEMSVFQGQQPPDWGQILAFGVLLVLPVLIVFAFFQRWFVQGVASSAVKG" misc_feature complement(2127..2142) /note="TFBS match to DasR, N-acetylglucosamine dependent repressor, confidence: medium, score: 22.93" /tool="antismash" gene 2243..3511 /locus_tag="SSOG_RS38080" /old_locus_tag="SSOG_07553" CDS 2243..3511 /GO_function="GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]" /GO_process="GO:0005975 - carbohydrate metabolic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014152519.1" /locus_tag="SSOG_RS38080" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07553" /product="glycoside hydrolase family 16 protein" /protein_id="WP_039939673.1" /transl_table=11 /translation="MDSPRLPRRLLLSFASVLALMSLSTGLAQGAPVSAVDPAAPPAAA AAVTFSDEFDGPAGSAVDGGKWQIETGDNVNNHERQYYTAGNRNAALDGQGHLVITARR ENPGNYQCWYGRCEYTSARLNTSGKFTTTYGRVEARMKVPRGQGMWPAFWMLGNDIGQV GWPNSGEIDIMENVGFEPSTVHGTLHGPGYSGSGGIGAGYTLPGGQAFADAFHTFAVDW SPNAITWSVDGTVYQRRTPADLGGRQWAFNKPFFLILNLAVGGYWPGDPDGSTAFPQQL LVDYVRVSTDSAQPGGGAITGVGGKCVDVAGADNANGTPVQLYDCNGSAAQQWTVGSDG TIRALGKCLDVASGGTADGTPVQLYDCNGSAAQQWAVPAARDIVNPQADKCLDATGGGS ANGTRLQIWTCTGAANQKWTVTR" misc_feature 2270..2272 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene 3625..4092 /locus_tag="SSOG_RS38085" CDS 3625..4092 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003995120.1" /locus_tag="SSOG_RS38085" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="DUF3592 domain-containing protein" /protein_id="WP_039942384.1" /transl_table=11 /translation="MRFQVRGRGGRRWVPFVVIAFGALFLAIGLILAGVSASFLTDAKR ARGTVVSLEWRNDHETSPRTQTDDKPAAYPVVAFTSADGAPRKFEDSTGSNPPSYELGE RVEVLYAPGSPEDARINGFASLWLMPLIFGGIGFVIAGIGTGVAVATRRRS" gene 4112..4525 /locus_tag="SSOG_RS38090" /old_locus_tag="SSOG_07554" CDS 4112..4525 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018534391.1" /locus_tag="SSOG_RS38090" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07554" /product="hypothetical protein" /protein_id="WP_039939674.1" /transl_table=11 /translation="MPRHPKKPRRLVAEGRAYLWTLRHSHRVLDSGRAADCRETLTLYP QPPGTGGPLRIVFADGPGRYVPGGFPLGSGDVGYVRGGSLNLHEPGAVRALLDAASARG WQPGDRRAAEVDGWPLLEAAVAARAGDVGPHGP" tRNA 4516..4618 /anticodon=(pos:8924208..8924210,aa:Pro,seq:ggg) /inference="COORDINATES: profile:tRNAscan-SE:2.0.12" /locus_tag="SSOG_RS52755" /note="Derived by automated computational analysis using gene prediction method: tRNAscan-SE." /product="tRNA-Pro" gene 4516..4618 /locus_tag="SSOG_RS52755" gene complement(5135..>5415) /locus_tag="SSOG_RS38095" /old_locus_tag="SSOG_07555" /pseudo="" CDS complement(5135..>5415) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020123585.1" /locus_tag="SSOG_RS38095" /note="frameshifted; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07555" /product="DNA-binding protein" /pseudo="" /transl_table=11 /translation="TSGATLVEAARPRINRPALE" gene 5541..5900 /locus_tag="SSOG_RS38100" /old_locus_tag="SSOG_07556" CDS 5541..5900 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018523664.1" /locus_tag="SSOG_RS38100" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07556" /product="hypothetical protein" /protein_id="WP_009719640.1" /transl_table=11 /translation="MGSGSGGGRVLDIKVADIKSVSPTFHHQAVKLSEALTTLINTLDG YGGPWGDDKPGKDFAKHYKPNQKHIESATGVLVLGLTSIHEAMQDMADGHVDNDKLIEG MFTKAKNAPGKDGHK" gene 5954..9544 /locus_tag="SSOG_RS38105" /old_locus_tag="SSOG_07557" CDS 5954..9544 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF040127.3" /locus_tag="SSOG_RS38105" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07557" /product="DUF6531 domain-containing protein" /protein_id="WP_342634381.1" /transl_table=11 /translation="MWWPDANSGTLRHAADAWRTFADTVDDVRAATNKAATTLIHNNKG EAIDAFETFWGRYAKGKDEGWLSDLATSARSMAKALDKFADKVDEAIEELWTQIAIDAV AIVAGGLLTLPTGGASDAVAGEIIAMAAGLGVAVEGAVATIAAEMLVGAVYTSIASVTV DLAVAQPAKIALGQQGGFSLDEVNAAAKDGMIYGGLFGAGAGVLKPGVLPKTGGVPGLL KPPGIRPNLIGKGPAGRFAKETPKVGEPIDIATGAMLMEQTDLTLPGSLPLVFERTHMS SYRGGVSFGPTWSCLLDERIQLDSEGVVFAAADGMRLVYPVPEPDVPTLPEKGARWPLE WDGKPDGVMTVTDPGTGVVRTFTRPAPTEESSAVHLWLESLQDRNGTRIDIERALAGNP LAIRHSGGYYVAVDTDEHRRVTALRLLDEAPSIYEPQGRDGAGTMVMRYAYDEAGHLAE VINSSNQPMRYTYDAQGRVTSWTDRNGTSFAYVYGPDGRVIRTEGSDGVYNGTLEYDDA ARTTVYTDSLGHRTTYRYNTDGQVTEETDPLGHTTLTTWNTRGDRRLSVTDPMGHTTRY AYDEDGNLTAVTLPDGSEARATYNDLCQPVEVTEPGGTTWRHVYDGAGNLLTTTDPMGS TSTYGYTERGHLAEVTDALGSTTRLTPDRTGLPNAVTDPLGHTTSVRRDPFGRVVEATD PLGRTTRMGWTTEGKPGWREEPDGARESWTWDGEGNLLTHTGPAGNTTHQTSTHFDVPA TRTEPDGASYAFAYDTELRLTQVTNPQGLTWTYTYDPAGRLTAETDFNGRTLTYTHDAA GDLRTRTNGAGETLHFTRDVLGRTTEQRDESGARTTYAYDAQGTLTQATNPDVELTLER DAVGRVLSETVNGRTTTYAYDAAGRRIERTTPSGLRSVWTYDESGRPAQLTTGTAGTLT FTYDAAGRETERRIGESVTLTQTWDRADRLATQTINAGHRRETGRILQHRSYAYRLDGY LAEIRELTSGTRRFDLDSVGRVTAVHAHGWTETYAYDTAGNLTHATAPDHETPGDRSFT GTIIHRAGRTTYEHDAQGRLTRRTRKLLNGQTRTWTYTWNPEDRLTNATTPDGEHWHYT YDPLGRRISKQRLAADGTVAESVTFAWEDTRLAEQSTPEGKHTTWDYAPDTHRPLTQTD HTSLVREPGLATPHHPLGHGLPLPSKPGGR" gene 9591..10067 /locus_tag="SSOG_RS57995" CDS 9591..10067 /codon_start=1 /inference="COORDINATES: protein motif:HMM:TIGR03696.1" /locus_tag="SSOG_RS57995" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="RHS repeat-associated core domain-containing protein" /protein_id="WP_342634382.1" /transl_table=11 /translation="MHYNYHRHYDAETARYITPDPLGIEPALNDYAYVADPLSWIDPLG LAGCKAGKVNWVTEGTTRSAAADAYESGAHGARSEVSSQKRLVPSLDYVKADGTPGAVR FDGLRDGQLIDRKLGVATTPKSKLGRDQAIHGSRPERANSCLGGGGSTCVPAGY" gene 10119..10367 /locus_tag="SSOG_RS38110" /old_locus_tag="SSOG_07558" CDS 10119..10367 /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS38110" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_07558" /product="hypothetical protein" /protein_id="WP_009719642.1" /transl_table=11 /translation="MNAIIARALIELLVSLELSDEESVSVEASAALAEDAATSLGALSD TERAELISIITQMAEEAGDEDRRQVLLDLPEGLGLTE" gene complement(10661..11299) /locus_tag="SSOG_RS38115" /old_locus_tag="SSOG_07559" CDS complement(10661..11299) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS38115" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_07559" /product="leucine-rich repeat domain-containing protein" /protein_id="WP_009719643.1" /transl_table=11 /translation="MEPAIAEAITLEVGHPAPFRDEELDSIMDLVVHHARGSSGLERCK SLRILILSGHGSNKIPDLGGFPALESLTVSDSDVRDIGAVRTAPSLLVLSVERNLVADI SPTLECARLTLLDVRGNPLSDMSYREVIPELRDKGVDVQASEEREWALTRALHAAGLPF SYYQYGDHHRLSRPGLTRTDTPEGGHIKITPQELEHLLVTSPSDIEALF" gene complement(11303..15508) /locus_tag="SSOG_RS38120" /old_locus_tag="SSOG_07560" CDS complement(11303..15508) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014057304.1" /locus_tag="SSOG_RS38120" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07560" /product="hypothetical protein" /protein_id="WP_167542532.1" /transl_table=11 /translation="MAGNAAMAAAMGGAPPGAGPGPFPSWWAGQLLPGGQDLIGNQAVA AQAGALPAAQQSPSAQLPEQQQSARKPDAKKPEPKPVRKAKAPPAPRPVQKDQQDQKDR KETEDRPGKGAKKQEATGPRSPGADPKFQALKKDVAAKKQRVASSHPPPAAEAGAAQGA AVPPADDQEARGKAAHAEDMDAAQPKEFDKQSFIAAVEKAIKDRAPKNLDEADKFGESG KAEEVKTEVQGKVGEGKDAAGQEIADTTAATPEPAPDAKEVVPLAADSVPGKPGAPNPN QAAPDALPKSATDMSAGPDQVNQQMASAQVTEQQLSMKNSGEPAFDKAVRDKKTMEAHS AAAPKELRAGEAAELKKVKATAATSGAAAMGALHATRVATGQQVTTGKEGTKGRDEDKR TKVTALLQKVFDETKGDVEEILSGLDKKVDTQFTNGEKRARDRFTDEHTRGMDEYKSRR YSGLRGKARWVKDLFADLPEEANRIYERARDNYLTAMRQVISDVADTVEGELRHAKDRI AKGRKDLQHTVDTLPKDLRAIGREAAADFQGKFDELSDTVNDKGTELVDTLATKYTEAV KSVDAEIAAEKEKNKGLVSKAADAIGGVINTIKELGRLLMGVLRKAASAVGLILKDPVG FLGRLITGVGGGLNLFMKNAGRHLQQGVLAWLLGSGVTAGLVLPTSFDVLGILVMIAGL LGLSWPNIRARLARKVNPKTMAAAETGKDAIPIVVEAKRRGVAGLWSDLKSRVGDLKKD LISKLVSYLLPTIIIAGVTWIVSLFNPASAFIRACKMIIDIVRFIVTQGRQIIEFVNTV LDAVIAIARGGTGGVPALVERALARSIPVLIGALAAILGIGGIAGKVKQIFQALSRPVS RAIDWVITKITGLLKKLAAKLKPKRKKPKRPQHRRKPTRPRRPRRPAKPKRPRKAKKPD RRKNRKREDRRTDQDKRRALDAAIRDANRLIGDGNATVKSVRAGLPDIKRRHRLTSISL KKSGDLHHIRLAINPNGKSKDAALEFDFANTGKVFAEKVHTSWWDKLLSKAKSGSNKQL WQRSVLDKTESEAVKYAGSQSVTQFREKHPRAADNKEVAVTYLFKAGSAIRTTFLDKLG GDEGALPKLKTTGKKAAEGDEKTVNDVEEMVFDPALGTYGRWDPFPSRDADADKDLVAA VKLAGGLDGFLETMVRTRRVGDVNWTRFGWLWDNDTPSREFIKGHFRDLNPGTHEWIPT NYILQVLEVAIAQHKRGNVEKGLDWLRLQDALRSPTNVVIWRILDGEGLVSLGAHVGTF YTDDRKPTLTNGTKEFHDRLRALYMQNRTGTARAYVTLLIEMLGSDAQAGPSGFQLMWS GGVGAIPSEALGRSIDVLFREKPGDLKKLTLLELSGKQKKAFAAVRLTFAKARDALKG" misc_feature 15731..15746 /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2, activator of antibiotic production, confidence: strong, score: 18.33" /tool="antismash" gene complement(15764..16372) /locus_tag="SSOG_RS38125" /old_locus_tag="SSOG_07561" CDS complement(15764..16372) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1215: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006125313.1" /locus_tag="SSOG_RS38125" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07561" /product="TetR family transcriptional regulator" /protein_id="WP_009719645.1" /transl_table=11 /translation="MTTRPEVSLAQRKRQLVSDELTEAALKLLARKGFDAVTVDEIVIA AGVSKRTFFRYFASKEDVVIQFLAEMGTGMRAELASRPAQESPSVALRHTVWVSIDACA GHADQALRVVQLILGTPALRARFLERQAQWRDGLATEVADRLDLDPATDLYPQLAAGIA LTAFDAVLQRWSDSDGVEDPAALTDRAFAVIAPALDAVA" misc_feature 16340..16358 /note="TFBS match to DmdR1, Iron(II)-dependent repressor, confidence: weak, score: 22.52" /tool="antismash" gene 16456..17391 /locus_tag="SSOG_RS38130" /old_locus_tag="SSOG_07562" CDS 16456..17391 /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /NRPS_PKS="Domain: PKS_KR (18-108). E-value: 1.8e-09. Score: 29.7. Matches aSDomain: nrpspksdomains_SSOG_RS38130_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1001: short-chain dehydrogenase/reductase SDR" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018105641.1" /locus_tag="SSOG_RS38130" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07562" /product="oxidoreductase" /protein_id="WP_039939676.1" /transl_table=11 /translation="MSNQQRWTAERIPDQSKRVVLVTGANSGLGLATTRALARKGAHVI LAVRDEAKGRRAVAEITAEYPAAQLEVRQLDLADLESVRAFSGQLHADHAHLDVLINNA GLMAPPRTLSPQGHEVQFAANHLGHFALTGLLLDLLEAGDNPRVVTVSSPNHRQGTIFF DDLSGERKYSPMGYYNQSKLANAVFGWELHKRLTAAGSPVRSVLAHPGYTSTNLQTSSP VGMVKFLFGRLLLPLAQSPDQGALSQLYAATAPGVEGGQFIGPDGMAELRGAPKRVALA ERASDAETCRRLWELSEELSDVRFAFSAAA" CDS_motif 16510..16593 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38130_0001" /evalue="2.70E-06" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38130" /protein_end="46" /protein_start="18" /score="20.0" /tool="antismash" /translation="VVLVTGANSGLGLATTRALARKGAHVIL" aSDomain 16510..16779 /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38130_PKS_KR.1" /evalue="1.80E-09" /label="SSOG_RS38130_PKS_KR.1" /locus_tag="SSOG_RS38130" /protein_end="108" /protein_start="18" /score="29.7" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C1" /tool="antismash" /translation="VVLVTGANSGLGLATTRALARKGAHVILAVRDEAKGRRAVAEITA EYPAAQLEVRQLDLADLESVRAFSGQLHADHAHLDVLINNAGLMA" misc_feature complement(17468..17483) /note="TFBS match to CRP, Cyclic AMP receptor protein, confidence: medium, score: 17.13" /tool="antismash" misc_feature complement(17586..17596) /note="TFBS match to HypR, L-hydroxyproline utilization repressor, confidence: weak, score: 18.59" /tool="antismash" misc_feature 17653..17668 /note="TFBS match to CopR, Copper-responsive regulator, confidence: weak, score: 17.85" /tool="antismash" gene 17819..18808 /locus_tag="SSOG_RS38135" /old_locus_tag="SSOG_07563" CDS 17819..18808 /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) p450" /gene_functions="biosynthetic-additional (smcogs) SMCOG1007: cytochrome P450" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012296.4" /locus_tag="SSOG_RS38135" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07563" /product="cytochrome P450" /protein_id="WP_208867403.1" /sec_met_domain="p450 (E-value: 9.6e-22, bitscore: 76.4, seeds: 50, tool: rule-based-clusters)" /transl_table=11 /translation="MLNPIPPKQDDASGLFIFMDGDAHSRFRRMLTAEFMIKNIRRIEP LIEKDVIEALERMRSLGAPADLMNEFALPVPSMTICHLLGVPYADHDFFQHHSRVIMDR KSGPAEVEEALGALTVLLGNLVKAKRTDPGEDLLSRLVAERVVPGELREDELVSLAMLL LVAGHETTANMIGLSALVLLEHPEHLAALREDPGLAPGMVEELLRYLTVVRTGLPRLAL EDAEIGGQKIRAGEGVVAMLAMSNRDSSVFGDPDEFDPKRREAHRHMAFGFGLHQCIGQ PLARAELRIALLELARRFPGLRSERALADVPQRPMAVTFGVAELPVTW" gene 18811..19020 /locus_tag="SSOG_RS38140" /old_locus_tag="SSOG_07564" CDS 18811..19020 /GO_function="GO:0005506 - iron ion binding [Evidence IEA]" /GO_function="GO:0009055 - electron transfer activity [Evidence IEA]" /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]" /codon_start=1 /gene_functions="other (smcogs) SMCOG1265: ferredoxin" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_008414609.1" /locus_tag="SSOG_RS38140" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07564" /product="ferredoxin" /protein_id="WP_039942389.1" /transl_table=11 /translation="MRITVNRELCVGSGNCVANVPEVFDQDDEEGLVRLQITEPPEELH ELVEVAAQMCPVGAIDVQYRVTTQ" misc_feature 19132..19150 /note="TFBS match to LexA_variant_3, Repressor of DNA damage response, confidence: weak, score: 19.77" /tool="antismash" gene 19258..19794 /locus_tag="SSOG_RS38145" /old_locus_tag="SSOG_07565" CDS 19258..19794 /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_process="GO:0000160 - phosphorelay signal transduction system [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family DNA-binding response regulator" /gene_kind="regulatory" /inference="COORDINATES: protein motif:HMM:NF012422.4" /locus_tag="SSOG_RS38145" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07565" /product="response regulator transcription factor" /protein_id="WP_009719649.1" /transl_table=11 /translation="MVVGEAGDIVELLSAVNPCVPDVVVLEGQSQIGHVQELTGIDAAL VVVGDVDTTTRWIGLTQANVHALVHCDDPEEELVEAVRRASDGTGYVSPGLSGALLRFT RAMLPRHLSAVPTHAPLTSRESEVLQLVRKGMANKEIARRLGLSEKTVKFHVSNVLAKA HVASRAQLIASGAAM" gene 20001..29231 /locus_tag="SSOG_RS55125" /old_locus_tag="SSOG_07566" CDS 20001..29231 /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (14-427). E-value: 1e-164. Score: 540.4. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_KS.1" /NRPS_PKS="Domain: PKS_AT (527-804). E-value: 1.3e-91. Score: 299.0. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_AT.1" /NRPS_PKS="Domain: ACP (898-966). E-value: 1.7e-23. Score: 74.7. Matches aSDomain: nrpspksdomains_SSOG_RS55125_ACP.1" /NRPS_PKS="Domain: PKS_KS(Modular-KS) (991-1417). E-value: 2.1e-184. Score: 605.3. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_KS.2" /NRPS_PKS="Domain: PKS_AT (1525-1819). E-value: 6.3e-106. Score: 346.0. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_AT.2" /NRPS_PKS="Domain: PKS_DH (1885-2054). E-value: 1.3e-61. Score: 199.7. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_DH.1" /NRPS_PKS="Domain: PKS_KR (2308-2485). E-value: 3.5e-58. Score: 188.5. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_KR.1" /NRPS_PKS="Domain: ACP (2592-2664). E-value: 1.2e-27. Score: 88.0. Matches aSDomain: nrpspksdomains_SSOG_RS55125_ACP.2" /NRPS_PKS="Domain: PKS_KS(Modular-KS) (2686-3073). E-value: 7e-165. Score: 541.0. Matches aSDomain: nrpspksdomains_SSOG_RS55125_PKS_KS.3" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) T1PKS: mod_KS" /gene_functions="biosynthetic (rule-based-clusters) T1PKS: PKS_KS" /gene_functions="biosynthetic (rule-based-clusters) T1PKS: PKS_AT" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) ketoacyl-synt" /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (smcogs) SMCOG1021: malonyl CoA-acyl carrier protein transacylase" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:NF012901.4" /locus_tag="SSOG_RS55125" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07566" /product="type I polyketide synthase" /protein_id="WP_050800088.1" /sec_met_domain="PKS_KS (E-value: 1.6e-162, bitscore: 540.4, seeds: 2284, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore: 47.0, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="mod_KS (E-value: 1.4e-227, bitscore: 754.7, seeds: 217, tool: rule-based-clusters)" /sec_met_domain="ketoacyl-synt (E-value: 1.7e-93, bitscore: 311.9, seeds: 77, tool: rule-based-clusters)" /sec_met_domain="PKS_AT (E-value: 1e-103, bitscore: 346.0, seeds: 1682, tool: rule-based-clusters)" /sec_met_domain="adh_short (E-value: 4.1e-59, bitscore: 198.5, seeds: 230, tool: rule-based-clusters)" /transl_table=11 /translation="MSGVQETGGARDTAIAVIGAACRVPSASSPAEFWRLLSEGTDAVS PWPTERGEGSRSWRGGFLDEVGTFDAAFFGMEPDEAAAVDPQQRLALELVWEAMEDAGV RGERLRGSRTGVFVGVSSDDYAALAARGDRAGRGELHDFTGRHRAIVANRVSWSFGLQG PSLAVDAAQASSLVAVHLACESLRRGDSDLAFAGGVNLILSADSMRTTAGLGALSAKGR CAAFDESADGFVRGEGGGVVLLKPLARAVADGDPIYCVIQGSAVNNDGGGDRLTDPDVA GQRDVLHRAYADARISPETVQYVELHGTGTPVGDPVEAAAVSDVIGRSSGDRGPLRVGS VKTNVGHLEAAAGIVGLLKAALSLRHRQLPPSLHFSTPNPAIPLAELNLRVQTELDAWP APDAPLVAGVSSFGIGGTNCHVVLAEAPYTGRPDTAVNRPETARPVPWVLSARTGRALD AQATRLLTHLEQQPDTHVADIARSLAVGRSTFEHRAVVVGTDRDGLTSSLARLHDDAVN GIATSGRTAFLFSGGGSQRVGMGRELYETYPVFADALDEVLDHFVPGLDLREVLLGGLD DDAAADALDGMRYMQPALFAFQVALYRLVTSWGVTPDLLVGHSFGEIVAAHVSGALPLA HAAALVAARGELMEELPPGGAMIAVEATEEEALAALDGVDDVSIGVINGPRAVVLSGAD EAVTRIADEFRARGHRTSRLRVQNAAHSPLTAPMLDEFARRIRGLAVSEPGIPIVSTVT GRTGAALTEDYWIGHLGATVRFHDAIAACREQGVTRFLELGPGSALTPLVPTSDTDLAV ALQHRDRPEPQALLTGLAEAWCAGVSVDWAETVGEARTVGLPTYAFQRRRYWLDERPAA AEAEQHVSSATLALRERIGTEPDGFLIRWLADHMAETTGAAPADPDATFRDLGLDSVLS VQLRNRLVSATGLRMPASILFDYPTPSALAAHLHDQILGVLGTVDDTRTTAPVTTATDD DPIAIVGMACHLPGGIDSPQELWQALVTEVDATSEFPTDRGWDLAGLYDPDPDHPGTTY SRRGGFLAGATDFDAEFFGISPREAAAMDPQQRLLLETAWEALERSGVDPASLRGSRTG VFVGAMNMEYGPHLHAPVDGTEGFRLTGNTSSVASGRISYQLGLEGPAMTVDTACSSSL VALHLAVQSLRNGECSMALAGGVTVLSTPGMFVEFSRQRGLAADGRCKPFSDDADGTGW AEGVGMLVVERLSEAEKHGHQVLAVVRGSAVNQDGGSNGLTAPNGPSQQRVIRDALAGA RLTSADVDVVEAHGTGTSLGDPIEAQALLATYGQGRDADRPLWLGSVKSNIGHTQAAAG VAGVIKMVQAMRNGVLPRSLHVSVPSRHVDWESGDVRVLTSHQEWPELERPRRSAVSSF GISGTNAHVILEAAPAEVGAAVQEVEPVRESSVPWVLSARSEAALAEQAARLLARVGDG ADLDARDVGFTLAGGRAVLEHRAVVLGGDGAELKAGLAELAAGRLASNVVEGRAGAGAS SGVVLVFPGQGSQWVGMARELLEFSPVFASRMAECAAALEPYVDGWSLLDVVRGGDEDV LRRVDVVQPVLFAVMVSLAELWGSLGVRPAAVVGHSQGEIAAACVAGGLSLEDAARVVA LRSRAILRLSGRGGMVSVLAPEEQVAGRLSEGLQIAVVNGPEQVVVSGAPDELEVFLAG CEADGVQARRIAVDYASHSPQVEDLREELLDVLAGIEPRSGHVPLFSTVYGEVIDTADM DAEYWFTNLRETVRFDAALQKLLEAGHRVFVESSPHPVLVGAVTQAAEGSGVAGVTAVG TLRRREDERARLLQSVAEVFVAGVEVDWSSWVAGGRLVELPTYAFQRRRHWLPAGRSVV DAAGLGLRPAGHPLLGAAVPLAPQEGLVLTGQLSLHTHPWLEDHAVFGTVLLPGTAFVE MALRAGDEVGCAVVEELTLERPLVLSAEALVAMQVSVGAPDDRGRRSVSVHSRVQGADA GAEAGVEWVRHAVGVLAAAGPVAEERLEGVWPPSGAESVDVAEAYELLSGVGYGYGPVF RGLRSVWRAGDELFAEVQLPAEPDAFGVHPALLDAALHPLPSGDMKVPFSWSGVRLHSV GASVVRVRLSPRGDGAVSVAAFDGAGLPVVTVDELRLQSMSQEQLGSAVAADPLYEVRW TDVPVPDGSGGVPPEVVVEYVEPGGDVRTSVAEVLESVQRFLAESADAESADREDTRGG MTGTQDPATAAVWGLLRSAQAEHPGRIVVVDTAEGADPNEAVALALASEPQVALKEGRF LVPRLVAHAPEAATAPDWKPDGTVLITGAGGALGQLVARHLVAEHGVRQLLLVSRRGGE GSEELVAELTEAGATVAFAACDVADREALSVALAGIPGEHPLTAVIHAAGVLDDGVVTA LTRERVDTVMRPKADGARLLDELTRDADLAAFVLFSSAAGVMGTAGQGNYAAANAFLDA LALSRRAEGLAATSMAWGLWTSDSAMTAHLDDADIARLSRSGLGSMSTSQGLALLDAAL AADRPTIVPARLDLSALRNHAARGTLPAVFKSLVRAPARRAAAVVGTGQSSSWIADMAA LDDGDRAAALLELVGTQVSLVLGHGSALSVEADRAFRDLGFDSLTGLELRQRLQAATGL RLPSTLVFDYPTSNALVGFLEEQIRGTDAAPTGPVAVATATDDDPVVIVGMACRLPGGI DSPQALWQAALDGVDAITEFPDDRGWDIADLYDPDPDRAGKTYTRQGGFLHDAAVFDPG FFGISPREAAAMDPQQRLLLETAWEALERSGVDPTSLRGSRTGVFTGLMPMEYGPPLHE PIEGMDGFRMLGNASSVASGRIAYQLGLEGPAMTVDTACSSSLVALHLAAQALRNGECS LALAGGVTVMSTPTTFVEFSRQRAMSVDGRCKAFSDDADGAGWSEGVGLLVVERLSDAR RNGHQILAVVRGSAVNQDGGSNGLTAPNGPSQQRVIRDALAGARLTSADVDVVEAHGTG TSLGDPIEAQALLATYGQGRDEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVQAMRYGVM PRTLHADTPSQHVDWTSGPSAC" aSDomain 20043..21281 /ASF="found active site cysteine: False, scaffold matched GSSS: False" /ASF="found active site histidines: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_KS.1" /domain_subtypes="Hybrid-KS" /evalue="1.00E-164" /label="SSOG_RS55125_PKS_KS.1" /locus_tag="SSOG_RS55125" /protein_end="427" /protein_start="14" /score="540.4" /tool="antismash" /translation="IAVIGAACRVPSASSPAEFWRLLSEGTDAVSPWPTERGEGSRSWR GGFLDEVGTFDAAFFGMEPDEAAAVDPQQRLALELVWEAMEDAGVRGERLRGSRTGVFV GVSSDDYAALAARGDRAGRGELHDFTGRHRAIVANRVSWSFGLQGPSLAVDAAQASSLV AVHLACESLRRGDSDLAFAGGVNLILSADSMRTTAGLGALSAKGRCAAFDESADGFVRG EGGGVVLLKPLARAVADGDPIYCVIQGSAVNNDGGGDRLTDPDVAGQRDVLHRAYADAR ISPETVQYVELHGTGTPVGDPVEAAAVSDVIGRSSGDRGPLRVGSVKTNVGHLEAAAGI VGLLKAALSLRHRQLPPSLHFSTPNPAIPLAELNLRVQTELDAWPAPDAPLVAGVSSFG IGGTNCHVVLAEAP" aSModule 20043..22898 /complete /domains="nrpspksdomains_SSOG_RS55125_PKS_KS.1" /domains="nrpspksdomains_SSOG_RS55125_PKS_AT.1" /domains="nrpspksdomains_SSOG_RS55125_ACP.1" /locus_tags="SSOG_RS55125" /monomer_pairings="mal -> mal" /tool="antismash" /type="pks" CDS_motif 20253..20279 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0001" /evalue="7.30E-02" /label="PKSI-KS_m2" /locus_tag="SSOG_RS55125" /protein_end="93" /protein_start="84" /score="6.4" /tool="antismash" /translation="DPQQRLALE" CDS_motif 20487..20534 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0002" /evalue="7.60E-03" /label="PKSI-KS_m3" /locus_tag="SSOG_RS55125" /protein_end="178" /protein_start="162" /score="9.1" /tool="antismash" /translation="GPSLAVDAAQASSLVA" CDS_motif 20676..20714 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0003" /evalue="5.00E-04" /label="PKSI-KS_m4" /locus_tag="SSOG_RS55125" /protein_end="238" /protein_start="225" /score="13.2" /tool="antismash" /translation="FDESADGFVRGEG" CDS_motif 20907..20954 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0004" /evalue="9.80E-04" /label="PKSI-KS_m5" /locus_tag="SSOG_RS55125" /protein_end="318" /protein_start="302" /score="11.6" /tool="antismash" /translation="YVELHGTGTPVGDPVE" CDS_motif 21015..21059 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0005" /evalue="9.30E-04" /label="PKSI-KS_m6" /locus_tag="SSOG_RS55125" /protein_end="353" /protein_start="338" /score="11.7" /tool="antismash" /translation="GSVKTNVGHLEAAAG" CDS_motif 21579..21632 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0006" /evalue="4.00E-04" /label="PKSI-AT-mM_m1" /locus_tag="SSOG_RS55125" /protein_end="544" /protein_start="526" /score="13.1" /tool="antismash" /translation="FLFSGGGSQRVGMGRELY" aSDomain 21582..22412 /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific" /ASF="found active site serine: True, scaffold matched GHGE: True" /aSDomain="PKS_AT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_AT.1" /evalue="1.30E-91" /label="SSOG_RS55125_PKS_AT.1" /locus_tag="SSOG_RS55125" /protein_end="804" /protein_start="527" /score="299.0" /specificity="substrate consensus: mal" /specificity="PKS signature: Malonyl-CoA" /specificity="Minowa: mal" /tool="antismash" /translation="LFSGGGSQRVGMGRELYETYPVFADALDEVLDHFVPGLDLREVLL GGLDDDAAADALDGMRYMQPALFAFQVALYRLVTSWGVTPDLLVGHSFGEIVAAHVSGA LPLAHAAALVAARGELMEELPPGGAMIAVEATEEEALAALDGVDDVSIGVINGPRAVVL SGADEAVTRIADEFRARGHRTSRLRVQNAAHSPLTAPMLDEFARRIRGLAVSEPGIPIV STVTGRTGAALTEDYWIGHLGATVRFHDAIAACREQGVTRFLELGPGSALTPLVP" CDS_motif 21759..21812 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0007" /evalue="1.20E-02" /label="PKSI-AT-mM_m2" /locus_tag="SSOG_RS55125" /protein_end="604" /protein_start="586" /score="9.1" /tool="antismash" /translation="MRYMQPALFAFQVALYRL" CDS_motif 21825..21947 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0008" /evalue="6.40E-17" /label="PKSI-AT-M_m3" /locus_tag="SSOG_RS55125" /protein_end="649" /protein_start="608" /score="53.7" /tool="antismash" /translation="GVTPDLLVGHSFGEIVAAHVSGALPLAHAAALVAARGELME" CDS_motif 22044..22076 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0009" /evalue="4.80E-02" /label="PKSI-AT-M_m5" /locus_tag="SSOG_RS55125" /protein_end="692" /protein_start="681" /score="7.3" /tool="antismash" /translation="INGPRAVVLSG" CDS_motif 22290..22325 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0010" /evalue="7.20E-01" /label="PKSI-AT-M_m8" /locus_tag="SSOG_RS55125" /protein_end="775" /protein_start="763" /score="3.9" /tool="antismash" /translation="YWIGHLGATVRF" aSDomain 22695..22898 /ASF="found active site serine: True" /ASF="non-beta-branching ACP" /aSDomain="ACP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_ACP.1" /evalue="1.70E-23" /label="SSOG_RS55125_ACP.1" /locus_tag="SSOG_RS55125" /protein_end="966" /protein_start="898" /score="74.7" /tool="antismash" /translation="RWLADHMAETTGAAPADPDATFRDLGLDSVLSVQLRNRLVSATGL RMPASILFDYPTPSALAAHLHDQ" aSDomain 22974..24251 /ASF="found active site cysteine: True, scaffold matched GSSS: True" /ASF="found active site histidines: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_KS.2" /domain_subtypes="Modular-KS" /evalue="2.10E-184" /label="SSOG_RS55125_PKS_KS.2" /locus_tag="SSOG_RS55125" /protein_end="1417" /protein_start="991" /score="605.3" /tool="antismash" /translation="IAIVGMACHLPGGIDSPQELWQALVTEVDATSEFPTDRGWDLAGL YDPDPDHPGTTYSRRGGFLAGATDFDAEFFGISPREAAAMDPQQRLLLETAWEALERSG VDPASLRGSRTGVFVGAMNMEYGPHLHAPVDGTEGFRLTGNTSSVASGRISYQLGLEGP AMTVDTACSSSLVALHLAVQSLRNGECSMALAGGVTVLSTPGMFVEFSRQRGLAADGRC KPFSDDADGTGWAEGVGMLVVERLSEAEKHGHQVLAVVRGSAVNQDGGSNGLTAPNGPS QQRVIRDALAGARLTSADVDVVEAHGTGTSLGDPIEAQALLATYGQGRDADRPLWLGSV KSNIGHTQAAAGVAGVIKMVQAMRNGVLPRSLHVSVPSRHVDWESGDVRVLTSHQEWPE LERPRRSAVSSFGISGTNAHVILEAAP" aSModule 22974..27992 /complete /domains="nrpspksdomains_SSOG_RS55125_PKS_KS.2" /domains="nrpspksdomains_SSOG_RS55125_PKS_AT.2" /domains="nrpspksdomains_SSOG_RS55125_PKS_DH.1" /domains="nrpspksdomains_SSOG_RS55125_PKS_KR.1" /domains="nrpspksdomains_SSOG_RS55125_ACP.2" /locus_tags="SSOG_RS55125" /monomer_pairings="mmal -> Me-ccmal" /tool="antismash" /type="pks" CDS_motif 23229..23255 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0011" /evalue="5.60E-02" /label="PKSI-KS_m2" /locus_tag="SSOG_RS55125" /protein_end="1085" /protein_start="1076" /score="6.8" /tool="antismash" /translation="DPQQRLLLE" CDS_motif 23457..23504 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0012" /evalue="7.50E-07" /label="PKSI-KS_m3" /locus_tag="SSOG_RS55125" /protein_end="1168" /protein_start="1152" /score="21.0" /tool="antismash" /translation="GPAMTVDTACSSSLVA" CDS_motif 23646..23684 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0013" /evalue="2.60E-01" /label="PKSI-KS_m4" /locus_tag="SSOG_RS55125" /protein_end="1228" /protein_start="1215" /score="5.2" /tool="antismash" /translation="FSDDADGTGWAEG" CDS_motif 23880..23924 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0014" /evalue="6.50E-04" /label="PKSI-KS_m5" /locus_tag="SSOG_RS55125" /protein_end="1308" /protein_start="1293" /score="12.0" /tool="antismash" /translation="VEAHGTGTSLGDPIE" CDS_motif 23985..24029 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0015" /evalue="1.30E-03" /label="PKSI-KS_m6" /locus_tag="SSOG_RS55125" /protein_end="1343" /protein_start="1328" /score="11.3" /tool="antismash" /translation="GSVKSNIGHTQAAAG" CDS_motif 24570..24626 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0016" /evalue="3.90E-09" /label="PKSI-AT-mM_m1" /locus_tag="SSOG_RS55125" /protein_end="1542" /protein_start="1523" /score="28.2" /tool="antismash" /translation="VLVFPGQGSQWVGMARELL" aSDomain 24576..25457 /ASF="Methylmalonyl-CoA specific" /ASF="found active site serine: True, scaffold matched GHGE: True" /aSDomain="PKS_AT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_AT.2" /evalue="6.30E-106" /label="SSOG_RS55125_PKS_AT.2" /locus_tag="SSOG_RS55125" /protein_end="1819" /protein_start="1525" /score="346.0" /specificity="substrate consensus: mmal" /specificity="PKS signature: Methylmalonyl-CoA" /specificity="Minowa: mmal" /tool="antismash" /translation="VFPGQGSQWVGMARELLEFSPVFASRMAECAAALEPYVDGWSLLD VVRGGDEDVLRRVDVVQPVLFAVMVSLAELWGSLGVRPAAVVGHSQGEIAAACVAGGLS LEDAARVVALRSRAILRLSGRGGMVSVLAPEEQVAGRLSEGLQIAVVNGPEQVVVSGAP DELEVFLAGCEADGVQARRIAVDYASHSPQVEDLREELLDVLAGIEPRSGHVPLFSTVY GEVIDTADMDAEYWFTNLRETVRFDAALQKLLEAGHRVFVESSPHPVLVGAVTQAAEGS GVAGVTAVGTLRR" CDS_motif 24741..24806 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0017" /evalue="4.10E-10" /label="PKSI-AT-mM_m2" /locus_tag="SSOG_RS55125" /protein_end="1602" /protein_start="1580" /score="31.7" /tool="antismash" /translation="RRVDVVQPVLFAVMVSLAELWG" CDS_motif 24813..24923 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0018" /evalue="1.50E-18" /label="PKSI-AT-mM_m3" /locus_tag="SSOG_RS55125" /protein_end="1641" /protein_start="1604" /score="58.5" /tool="antismash" /translation="GVRPAAVVGHSQGEIAAACVAGGLSLEDAARVVALRS" CDS_motif 25020..25058 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0019" /evalue="1.20E-03" /label="PKSI-AT-M_m5" /locus_tag="SSOG_RS55125" /protein_end="1686" /protein_start="1673" /score="12.2" /tool="antismash" /translation="AVVNGPEQVVVSG" CDS_motif 25128..25160 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0020" /evalue="4.40E-04" /label="PKSI-AT-mM_m6" /locus_tag="SSOG_RS55125" /protein_end="1720" /protein_start="1709" /score="13.0" /tool="antismash" /translation="VDYASHSPQVE" CDS_motif 25266..25313 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0021" /evalue="3.30E-05" /label="PKSI-AT-mM_m8" /locus_tag="SSOG_RS55125" /protein_end="1771" /protein_start="1755" /score="16.0" /tool="antismash" /translation="MDAEYWFTNLRETVRF" aSDomain 25656..26162 /ASF="catalytic triad H,G,P found: False" /aSDomain="PKS_DH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_DH.1" /evalue="1.30E-61" /label="SSOG_RS55125_PKS_DH.1" /locus_tag="SSOG_RS55125" /protein_end="2054" /protein_start="1885" /score="199.7" /tool="antismash" /translation="HPLLGAAVPLAPQEGLVLTGQLSLHTHPWLEDHAVFGTVLLPGTA FVEMALRAGDEVGCAVVEELTLERPLVLSAEALVAMQVSVGAPDDRGRRSVSVHSRVQG ADAGAEAGVEWVRHAVGVLAAAGPVAEERLEGVWPPSGAESVDVAEAYELLSGVGYGYG PVFRGL" CDS_motif 25740..25814 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0022" /evalue="1.90E-11" /label="PKSI-DH_m2" /locus_tag="SSOG_RS55125" /protein_end="1938" /protein_start="1913" /score="36.3" /tool="antismash" /translation="WLEDHAVFGTVLLPGTAFVEMALRA" aSDomain 26925..27455 /ASF="KR domain putatively catalyzing D-configuration product formation" /ASF="catalytic triad S,Y,N inconclusive" /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_KR.1" /evalue="3.50E-58" /label="SSOG_RS55125_PKS_KR.1" /locus_tag="SSOG_RS55125" /protein_end="2485" /protein_start="2308" /score="188.5" /specificity="KR activity: active" /specificity="KR stereochemistry: B1" /tool="antismash" /translation="GTVLITGAGGALGQLVARHLVAEHGVRQLLLVSRRGGEGSEELVA ELTEAGATVAFAACDVADREALSVALAGIPGEHPLTAVIHAAGVLDDGVVTALTRERVD TVMRPKADGARLLDELTRDADLAAFVLFSSAAGVMGTAGQGNYAAANAFLDALALSRRA EGLAATSMAWGLWT" CDS_motif 26928..27029 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0023" /evalue="5.70E-08" /label="PKSI-KR_m1" /locus_tag="SSOG_RS55125" /protein_end="2343" /protein_start="2309" /score="25.4" /tool="antismash" /translation="TVLITGAGGALGQLVARHLVAEHGVRQLLLVSRR" CDS_motif 27303..27410 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0024" /evalue="2.20E-18" /label="PKSI-KR_m4" /locus_tag="SSOG_RS55125" /protein_end="2470" /protein_start="2434" /score="58.8" /tool="antismash" /translation="AAFVLFSSAAGVMGTAGQGNYAAANAFLDALALSRR" aSDomain 27777..27992 /ASF="found active site serine: True" /ASF="non-beta-branching ACP" /aSDomain="ACP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_ACP.2" /evalue="1.20E-27" /label="SSOG_RS55125_ACP.2" /locus_tag="SSOG_RS55125" /protein_end="2664" /protein_start="2592" /score="88.0" /tool="antismash" /translation="LELVGTQVSLVLGHGSALSVEADRAFRDLGFDSLTGLELRQRLQA ATGLRLPSTLVFDYPTSNALVGFLEEQ" aSDomain 28059..29219 /ASF="found active site cysteine: True, scaffold matched GSSS: True" /ASF="found active site histidines: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55125_PKS_KS.3" /domain_subtypes="Modular-KS" /evalue="7.00E-165" /label="SSOG_RS55125_PKS_KS.3" /locus_tag="SSOG_RS55125" /protein_end="3073" /protein_start="2686" /score="541.0" /tool="antismash" /translation="VVIVGMACRLPGGIDSPQALWQAALDGVDAITEFPDDRGWDIADL YDPDPDRAGKTYTRQGGFLHDAAVFDPGFFGISPREAAAMDPQQRLLLETAWEALERSG VDPTSLRGSRTGVFTGLMPMEYGPPLHEPIEGMDGFRMLGNASSVASGRIAYQLGLEGP AMTVDTACSSSLVALHLAAQALRNGECSLALAGGVTVMSTPTTFVEFSRQRAMSVDGRC KAFSDDADGAGWSEGVGLLVVERLSDARRNGHQILAVVRGSAVNQDGGSNGLTAPNGPS QQRVIRDALAGARLTSADVDVVEAHGTGTSLGDPIEAQALLATYGQGRDEDRPLWLGSV KSNIGHTQAAAGVAGVIKMVQAMRYGVMPRTLHADTPSQHVDWTSGP" CDS_motif 28314..28340 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0025" /evalue="5.60E-02" /label="PKSI-KS_m2" /locus_tag="SSOG_RS55125" /protein_end="2780" /protein_start="2771" /score="6.8" /tool="antismash" /translation="DPQQRLLLE" CDS_motif 28542..28589 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0026" /evalue="7.50E-07" /label="PKSI-KS_m3" /locus_tag="SSOG_RS55125" /protein_end="2863" /protein_start="2847" /score="21.0" /tool="antismash" /translation="GPAMTVDTACSSSLVA" CDS_motif 28731..28769 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0027" /evalue="1.20E+00" /label="PKSI-KS_m4" /locus_tag="SSOG_RS55125" /protein_end="2923" /protein_start="2910" /score="3.2" /tool="antismash" /translation="FSDDADGAGWSEG" CDS_motif 28965..29009 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0028" /evalue="6.50E-04" /label="PKSI-KS_m5" /locus_tag="SSOG_RS55125" /protein_end="3003" /protein_start="2988" /score="12.0" /tool="antismash" /translation="VEAHGTGTSLGDPIE" CDS_motif 29070..29114 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55125_0029" /evalue="1.30E-03" /label="PKSI-KS_m6" /locus_tag="SSOG_RS55125" /protein_end="3038" /protein_start="3023" /score="11.3" /tool="antismash" /translation="GSVKSNIGHTQAAAG" gene 29228..>31190 /locus_tag="SSOG_RS55130" /old_locus_tag="SSOG_07567" CDS 29228..>31190 /NRPS_PKS="Domain: PKS_AT (143-446). E-value: 4.5e-104. Score: 339.9. Matches aSDomain: nrpspksdomains_SSOG_RS55130_PKS_AT.1" /NRPS_PKS="Domain: PKS_DH (517-625). E-value: 1e-40. Score: 131.8. Matches aSDomain: nrpspksdomains_SSOG_RS55130_PKS_DH.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PKS_AT" /gene_functions="biosynthetic-additional (smcogs) SMCOG1021: malonyl CoA-acyl carrier protein transacylase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012901.4" /locus_tag="SSOG_RS55130" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07567" /product="type I polyketide synthase" /protein_id="WP_245606670.1" /sec_met_domain="PKS_AT (E-value: 7.1e-102, bitscore: 339.9, seeds: 1682, tool: rule-based-clusters)" /transl_table=11 /translation="MTSHQSWPESDRPRRSAVSSFGISGKNAHVILEAAPEDTTAPDPG PAPEAPMIPWALSAKTSAGVRRQAARLLARITDDPGLDPRDVGYTLATGRALMEHRAVV LGAGLDELTGSLTALARGEDVPAAVAGAVPAAGAGGLALVFSGQGSQRPGTGRELYERY PVFAEAFDAVCAAVDEQLDGYAEHPLRDVAFAPEGSPLAPLLQQSMYTQTGLFALEVAL LELLKAWGVRPDHVMGHSLGEVTAVYAADALSLADACTLVAARGRLMQALPEGGAMVAI AVAEQEAEAYIAEASLQDAVGIAAVNGPRAVVVSGDEAAVVDVAEHFRAAGHRVRRLSV SHAFHSHRMDAMLDEFADVVAGLTFRAPRIPVVSNVTGGPIDTERLCTPQHWVEHVRRG VRFADGVRSLADQGVTAYLEVGPEAVVTPMVHATLDAVLGDDGYVAVAALKSGQGEALA LTRALARTFVAGTPVAWELLLPGGRRTELPGYPFAGHRYWQDASESTVGIRAAGLNATR HPLLGAAVHLADGQAVLTGRVLPGAHPWLADHAVGGTVLLPGTAFLDLALHAGHEVGCP LVEELTLRTPLVLSAGTAVNLQVALGAPDETGRRSVTVYSSPAAVSGTEPLGPARDRHA VRGTPARRRSVDLGRLPTP" aSDomain 29657..30565 /ASF="(Methyl)Malonyl-CoA specificity inconclusive" /ASF="found active site serine: True, scaffold matched GHGE: True" /aSDomain="PKS_AT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55130_PKS_AT.1" /evalue="4.50E-104" /label="SSOG_RS55130_PKS_AT.1" /locus_tag="SSOG_RS55130" /protein_end="446" /protein_start="143" /score="339.9" /specificity="substrate consensus: mal" /specificity="PKS signature: Malonyl-CoA" /specificity="Minowa: mal" /tool="antismash" /translation="VFSGQGSQRPGTGRELYERYPVFAEAFDAVCAAVDEQLDGYAEHP LRDVAFAPEGSPLAPLLQQSMYTQTGLFALEVALLELLKAWGVRPDHVMGHSLGEVTAV YAADALSLADACTLVAARGRLMQALPEGGAMVAIAVAEQEAEAYIAEASLQDAVGIAAV NGPRAVVVSGDEAAVVDVAEHFRAAGHRVRRLSVSHAFHSHRMDAMLDEFADVVAGLTF RAPRIPVVSNVTGGPIDTERLCTPQHWVEHVRRGVRFADGVRSLADQGVTAYLEVGPEA VVTPMVHATLDAVLGDDGYVAV" aSModule 29657..31102 /domains="nrpspksdomains_SSOG_RS55130_PKS_AT.1" /domains="nrpspksdomains_SSOG_RS55130_PKS_DH.1" /incomplete /locus_tags="SSOG_RS55130" /starter_module /tool="antismash" /type="pks" CDS_motif 29660..29707 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0001" /evalue="2.60E-05" /label="PKSI-AT-M_m1" /locus_tag="SSOG_RS55130" /protein_end="160" /protein_start="144" /score="16.8" /tool="antismash" /translation="FSGQGSQRPGTGRELY" CDS_motif 29915..30037 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0002" /evalue="4.70E-19" /label="PKSI-AT-M_m3" /locus_tag="SSOG_RS55130" /protein_end="270" /protein_start="229" /score="60.5" /tool="antismash" /translation="GVRPDHVMGHSLGEVTAVYAADALSLADACTLVAARGRLMQ" CDS_motif 30137..30175 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0003" /evalue="1.40E-04" /label="PKSI-AT-M_m5" /locus_tag="SSOG_RS55130" /protein_end="316" /protein_start="303" /score="15.0" /tool="antismash" /translation="AAVNGPRAVVVSG" CDS_motif 30239..30265 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0004" /evalue="1.70E-02" /label="PKSI-AT-M_m6" /locus_tag="SSOG_RS55130" /protein_end="346" /protein_start="337" /score="8.4" /tool="antismash" /translation="LSVSHAFHS" CDS_motif 30329..30361 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0005" /evalue="1.50E-03" /label="PKSI-AT-M_m7" /locus_tag="SSOG_RS55130" /protein_end="378" /protein_start="367" /score="11.2" /tool="antismash" /translation="PRIPVVSNVTG" aSDomain 30779..31102 /ASF="catalytic triad H,G,P found: False" /aSDomain="PKS_DH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55130_PKS_DH.1" /evalue="1.00E-40" /label="SSOG_RS55130_PKS_DH.1" /locus_tag="SSOG_RS55130" /protein_end="625" /protein_start="517" /score="131.8" /tool="antismash" /translation="HPLLGAAVHLADGQAVLTGRVLPGAHPWLADHAVGGTVLLPGTAF LDLALHAGHEVGCPLVEELTLRTPLVLSAGTAVNLQVALGAPDETGRRSVTVYSSPAAV SGTE" CDS_motif 30839..30934 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55130_0006" /evalue="7.10E-11" /label="PKSI-DH_m2" /locus_tag="SSOG_RS55130" /protein_end="569" /protein_start="537" /score="34.5" /tool="antismash" /translation="VLPGAHPWLADHAVGGTVLLPGTAFLDLALHA" gap 31191..32718 /estimated_length=1528 gene <32719..>33291 /locus_tag="SSOG_RS38155" /old_locus_tag="SSOG_07568" CDS 32721..>33291 /NRPS_PKS="Domain: PKS_KR (47-191). E-value: 4.5e-43. Score: 139.2. Matches aSDomain: nrpspksdomains_SSOG_RS38155_PKS_KR.1" /codon_start=2 /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (smcogs) SMCOG1001: short-chain dehydrogenase/reductase SDR" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF020243.4" /locus_tag="SSOG_RS38155" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07568" /product="SDR family NAD(P)-dependent oxidoreductase" /protein_id="WP_039939678.1" /sec_met_domain="adh_short (E-value: 7.8e-48, bitscore: 161.9, seeds: 230, tool: rule-based-clusters)" /transl_table=11 /translation="MFDTGALRALPVTAYDIRAAATAYRRLDEEAHTGGAVLTIPRPLD PDGTVLVTGASGTLGQLVLRRLVSEHGVRNVLLLSRSGGEAPEDLVERGVRVQSVACDA ADREQLARALARIPAEHPLTAVVHTAGVLDDGVLEALTPERLATVLRPKADAVGALHEL TADADLAAFVVFSSVAGVLGSPGQANYA" aSDomain 32863..>33291 /ASF="KR domain putatively catalyzing D-configuration product formation" /ASF="catalytic triad S,Y,N inconclusive" /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38155_PKS_KR.1" /evalue="4.50E-43" /label="SSOG_RS38155_PKS_KR.1" /locus_tag="SSOG_RS38155" /protein_end="191" /protein_start="47" /score="139.2" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C2" /tool="antismash" /translation="GTVLVTGASGTLGQLVLRRLVSEHGVRNVLLLSRSGGEAPEDLVE RGVRVQSVACDAADREQLARALARIPAEHPLTAVVHTAGVLDDGVLEALTPERLATVLR PKADAVGALHELTADADLAAFVVFSSVAGVLGSPGQANYA" CDS_motif 32866..33009 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38155_0001" /evalue="1.00E-07" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38155" /protein_end="96" /protein_start="48" /score="24.6" /tool="antismash" /translation="TVLVTGASGTLGQLVLRRLVSEHGVRNVLLLSRSGGEAPEDLVER GVR" CDS_motif 33229..>33291 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38155_0002" /evalue="1.70E-11" /label="PKSI-KR_m4" /locus_tag="SSOG_RS38155" /protein_end="191" /protein_start="169" /score="36.7" /tool="antismash" /translation="AAFVVFSSVAGVLGSPGQANYA" gap 33292..33460 /estimated_length=169 gene <33461..34248 /locus_tag="SSOG_RS47180" /old_locus_tag="SSOG_07569" CDS <33465..34248 /NRPS_PKS="Domain: PKS_PP (71-157). E-value: 9.7e-31. Score: 98.0. Matches aSDomain: nrpspksdomains_SSOG_RS47180_PKS_PP.1" /NRPS_PKS="Domain: PKS_Docking_Cterm (174-245). E-value: 2.6e-12. Score: 39.4. Matches aSDomain: nrpspksdomains_SSOG_RS47180_PKS_Docking_Cterm.1" /codon_start=3 /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012759.4" /locus_tag="SSOG_RS47180" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07569" /product="acyl carrier protein" /protein_id="WP_215490552.1" /sec_met_domain="PP-binding (E-value: 2.2e-14, bitscore: 52.8, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="GLLPTSTEEGLAAFDRALVGALPTVVPVRVDTAALRAADTVPPLL RELAPAPNRRAAASAPAAPAESLESRLRGLPAEQRSTLLLDLVLKDVALVLGHGDPRGI SADGAFRDLGFDSLTAVELRNKINHRTGLKLSATAVFDHPSPRALVDHLLDRLTAAPET ARDAEEPSYERVVADLTRVGNSLAALELTATQRAALAEVFRGLAEPWTGGEPVAAADEP ASADLESATAAEVLDFVTNSLGISISGDISGDGSPTDPS" misc_feature complement(33495..33504) /note="TFBS match to AbrC3, Antibiotic production activator, confidence: strong, score: 18.07" /tool="antismash" aSDomain 33679..33936 /aSDomain="PKS_PP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47180_PKS_PP.1" /evalue="9.70E-31" /label="SSOG_RS47180_PKS_PP.1" /locus_tag="SSOG_RS47180" /protein_end="157" /protein_start="71" /score="98.0" /tool="antismash" /translation="LRGLPAEQRSTLLLDLVLKDVALVLGHGDPRGISADGAFRDLGFD SLTAVELRNKINHRTGLKLSATAVFDHPSPRALVDHLLDRL" aSDomain 33988..34200 /aSDomain="PKS_Docking_Cterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS47180_PKS_Docking_Cterm.1 " /evalue="2.60E-12" /label="SSOG_RS47180_PKS_Docking_Cterm.1" /locus_tag="SSOG_RS47180" /protein_end="245" /protein_start="174" /score="39.4" /tool="antismash" /translation="VVADLTRVGNSLAALELTATQRAALAEVFRGLAEPWTGGEPVAAA DEPASADLESATAAEVLDFVTNSLGI" gene 34259..35179 /locus_tag="SSOG_RS55135" /old_locus_tag="SSOG_07570" CDS 34259..35179 /NRPS_PKS="Domain: PKS_Docking_Nterm (3-31). E-value: 4.1e-07. Score: 21.5. Matches aSDomain: nrpspksdomains_SSOG_RS55135_PKS_Docking_Nterm.1" /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-302). E-value: 2.9e-110. Score: 361.0. Matches aSDomain: nrpspksdomains_SSOG_RS55135_PKS_KS.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) mod_KS" /gene_functions="biosynthetic-additional (rule-based-clusters) ketoacyl-synt" /gene_functions="biosynthetic-additional (smcogs) SMCOG1022: Beta-ketoacyl synthase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012337.4" /locus_tag="SSOG_RS55135" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07570" /product="beta-ketoacyl synthase N-terminal-like domain-containing protein" /protein_id="WP_050800089.1" /sec_met_domain="mod_KS (E-value: 5.2e-132, bitscore: 439.8, seeds: 217, tool: rule-based-clusters)" /sec_met_domain="ketoacyl-synt (E-value: 6.9e-87, bitscore: 290.3, seeds: 77, tool: rule-based-clusters)" /transl_table=11 /translation="MPTEDELLKYLKAVSEELHVARGRLQTLEGRRSEPVAIVGMSCRL PGGVSSPDHLWDVVAKGEDAIGAFPADRGWDVDALYDPEPGTPGKTYTRSGGFLHDAAD FDPAFFGITPREAHGMDPQQRLMLEASWQALESAGINPQTLKGTRTGVFAGSFHHDYDP GGGSVGSLVSGRVAYALGLQGPAVTVDTACSSSLVALHQAVQSLREGECALALAGGVTV LSTPGVFIEFSRQRGLAADGRCKSYATAADGTGWGEGVAVLALERLSDAERHGHRVLAL VRGTAVNQDGASNGQTAPNGPHSSG" aSDomain 34268..34351 /aSDomain="PKS_Docking_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55135_PKS_Docking_Nterm.1 " /evalue="4.10E-07" /label="SSOG_RS55135_PKS_Docking_Nterm.1" /locus_tag="SSOG_RS55135" /protein_end="31" /protein_start="3" /score="21.5" /tool="antismash" /translation="EDELLKYLKAVSEELHVARGRLQTLEGR" aSDomain 34364..35164 /ASF="found active site cysteine: True, scaffold matched GSSS: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55135_PKS_KS.1" /domain_subtypes="Modular-KS" /evalue="2.90E-110" /label="SSOG_RS55135_PKS_KS.1" /locus_tag="SSOG_RS55135" /protein_end="302" /protein_start="35" /score="361.0" /tool="antismash" /translation="VAIVGMSCRLPGGVSSPDHLWDVVAKGEDAIGAFPADRGWDVDAL YDPEPGTPGKTYTRSGGFLHDAADFDPAFFGITPREAHGMDPQQRLMLEASWQALESAG INPQTLKGTRTGVFAGSFHHDYDPGGGSVGSLVSGRVAYALGLQGPAVTVDTACSSSLV ALHQAVQSLREGECALALAGGVTVLSTPGVFIEFSRQRGLAADGRCKSYATAADGTGWG EGVAVLALERLSDAERHGHRVLALVRGTAVNQDGASNGQTAPNGP" CDS_motif 34619..34645 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55135_0001" /evalue="4.30E-03" /label="PKSI-KS_m2" /locus_tag="SSOG_RS55135" /protein_end="129" /protein_start="120" /score="9.9" /tool="antismash" /translation="DPQQRLMLE" CDS_motif 34808..34855 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55135_0002" /evalue="1.00E-07" /label="PKSI-KS_m3" /locus_tag="SSOG_RS55135" /protein_end="199" /protein_start="183" /score="23.5" /tool="antismash" /translation="GPAVTVDTACSSSLVA" gene 35176..>38717 /locus_tag="SSOG_RS55140" /old_locus_tag="SSOG_07571" CDS 35176..>38717 /NRPS_PKS="Domain: PKS_AT (243-538). E-value: 9.3e-106. Score: 345.5. Matches aSDomain: nrpspksdomains_SSOG_RS55140_PKS_AT.1" /NRPS_PKS="Domain: PKS_DH (602-769). E-value: 3.3e-62. Score: 201.7. Matches aSDomain: nrpspksdomains_SSOG_RS55140_PKS_DH.1" /NRPS_PKS="Domain: PKS_KR (1057-1180). E-value: 1.2e-35. Score: 115.1. Matches aSDomain: nrpspksdomains_SSOG_RS55140_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) T1PKS: mod_KS" /gene_functions="biosynthetic (rule-based-clusters) T1PKS: PKS_AT" /gene_functions="biosynthetic-additional (rule-based-clusters) adh_short" /gene_functions="biosynthetic-additional (rule-based-clusters) Polysacc_synt_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1022: Beta-ketoacyl synthase" /gene_kind="biosynthetic" /inference="COORDINATES: protein motif:HMM:NF012901.4" /locus_tag="SSOG_RS55140" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07571" /product="type I polyketide synthase" /protein_id="WP_154686030.1" /sec_met_domain="mod_KS (E-value: 1.6e-72, bitscore: 243.8, seeds: 217, tool: rule-based-clusters)" /sec_met_domain="PKS_AT (E-value: 1.5e-103, bitscore: 345.5, seeds: 1682, tool: rule-based-clusters)" /sec_met_domain="adh_short (E-value: 2.8e-39, bitscore: 134.0, seeds: 230, tool: rule-based-clusters)" /sec_met_domain="Polysacc_synt_2 (E-value: 7.9e-05, bitscore: 21.0, seeds: 77, tool: rule-based-clusters)" /transl_table=11 /translation="MIQDALASARLTSADVDVVEGHGTGTTLGDPIEAQALLATYGQGR DEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVQAMRYGVMPRTLHVDEPSHHVDWSEGQV RLLTEDRAWPELERPRRAGVSSFGYSGTNAHVILEGAAPVQEAGPVRGGVLPWVLSARS EAALAEQAARLLARVGDGADLDPRDVGFTLAGGRAVLEHRAVVLGESDSELAAGLGELA AGRPVAGVVAGRAVSSGGVVLVFPGQGSQWVGMARELLEFSPVFASRMAECAAALGPYV DGWSLLDVVRGGDEDVLRRVDVVQPVLFAVMVSLAELWGSLGVRPAAVVGHSQGEIAAA CVAGGLSLEDAARVVALRSRAILRLSGRGGMVSVLAPEDQVAGRLSEGLQIAVVNGPEQ VVVSGAPDELEVFLAGCEADGVQARRIAVDYASHSPQVEDLKAELIDVLGEIEPRTGHI PLFSTVYGEVIDTADMDAEYWFTNLRETVRFDAALQKLLEAGHRVFVESSPHPVLLGAV TQNADHLRTTGVSAIGTLRRNEGEEAQLLRSLAEVFVAGVDVDWSPWVAGGRLVELPTY AFQRRRYWQPAASAADVGSAGLDAVRHPLLGAAVRLAGSDDVVLTGRISRATHPWLEDH AVFGTVLLPGTAFVEMALRAADEVGCDALRDLTLHAPLALPEQGEIDIQVQIGAGTGTG RPLDIYSRPRRHDGTAEWTQHASAVLATDAVPADINGPLFGAAWPPAGAERLDAADHYD TMAAAGLEYGPAFQGLSDVWRLGDEILAQVTLPGRQAEEAQRFALHPALLDAALQAAAV DGLDGRTPLPFSFGTVALHGRGASEVRVRIAPTGADTFTVEAADPSGTPVARIDSLLVR PVTAGDLATADGSTTALLSVEWSPYAADADASAVDPGADAPDVTLLKAADAGPAAGDEA ARARAVLRDTLRGVQEWLAQDRPASARLVVLTRRAVLTGAEEPDAAVDLAHAAVWGLAR AARAENPGRVVLLDVDGELDGLDEAAVHDALRTGRHELALREGKLYVPALRRQETAPVA DGVAEALGTGTVLITGGTSGLGAQVARHAARHGARHLLLLSRRGSAAEGAEALRDELAA SGARVTVRACDVADRDQLERALRDVPDAYPLTAVVHAAGVLHDAVVESIDAYGLDAVLR PKTDAAWHLHELTAG" CDS_motif 35230..35274 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0001" /evalue="1.60E-03" /label="PKSI-KS_m5" /locus_tag="SSOG_RS55140" /protein_end="33" /protein_start="18" /score="11.0" /tool="antismash" /translation="VEGHGTGTTLGDPIE" CDS_motif 35335..35379 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0002" /evalue="4.00E-04" /label="PKSI-KS_m6" /locus_tag="SSOG_RS55140" /protein_end="68" /protein_start="53" /score="12.7" /tool="antismash" /translation="GSVKSNIGHTQAAAG" CDS_motif 35899..35955 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0003" /evalue="1.30E-09" /label="PKSI-AT-mM_m1" /locus_tag="SSOG_RS55140" /protein_end="260" /protein_start="241" /score="29.6" /tool="antismash" /translation="VLVFPGQGSQWVGMARELL" aSDomain 35905..36789 /ASF="Methylmalonyl-CoA specific" /ASF="found active site serine: True, scaffold matched GHGE: True" /aSDomain="PKS_AT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55140_PKS_AT.1" /evalue="9.30E-106" /label="SSOG_RS55140_PKS_AT.1" /locus_tag="SSOG_RS55140" /protein_end="538" /protein_start="243" /score="345.5" /specificity="substrate consensus: mmal" /specificity="PKS signature: Methylmalonyl-CoA" /specificity="Minowa: mmal" /tool="antismash" /translation="VFPGQGSQWVGMARELLEFSPVFASRMAECAAALGPYVDGWSLLD VVRGGDEDVLRRVDVVQPVLFAVMVSLAELWGSLGVRPAAVVGHSQGEIAAACVAGGLS LEDAARVVALRSRAILRLSGRGGMVSVLAPEDQVAGRLSEGLQIAVVNGPEQVVVSGAP DELEVFLAGCEADGVQARRIAVDYASHSPQVEDLKAELIDVLGEIEPRTGHIPLFSTVY GEVIDTADMDAEYWFTNLRETVRFDAALQKLLEAGHRVFVESSPHPVLLGAVTQNADHL RTTGVSAIGTLRRN" aSModule 35905..38715 /domains="nrpspksdomains_SSOG_RS55140_PKS_AT.1" /domains="nrpspksdomains_SSOG_RS55140_PKS_DH.1" /domains="nrpspksdomains_SSOG_RS55140_PKS_KR.1" /incomplete /locus_tags="SSOG_RS55140" /starter_module /tool="antismash" /type="pks" CDS_motif 36070..36135 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0004" /evalue="1.40E-10" /label="PKSI-AT-mM_m2" /locus_tag="SSOG_RS55140" /protein_end="320" /protein_start="298" /score="33.2" /tool="antismash" /translation="RRVDVVQPVLFAVMVSLAELWG" CDS_motif 36142..36252 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0005" /evalue="5.20E-19" /label="PKSI-AT-mM_m3" /locus_tag="SSOG_RS55140" /protein_end="359" /protein_start="322" /score="60.0" /tool="antismash" /translation="GVRPAAVVGHSQGEIAAACVAGGLSLEDAARVVALRS" CDS_motif 36349..36387 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0006" /evalue="4.00E-04" /label="PKSI-AT-M_m5" /locus_tag="SSOG_RS55140" /protein_end="404" /protein_start="391" /score="13.6" /tool="antismash" /translation="AVVNGPEQVVVSG" CDS_motif 36457..36489 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0007" /evalue="1.50E-04" /label="PKSI-AT-mM_m6" /locus_tag="SSOG_RS55140" /protein_end="438" /protein_start="427" /score="14.4" /tool="antismash" /translation="VDYASHSPQVE" CDS_motif 36595..36642 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0008" /evalue="1.10E-05" /label="PKSI-AT-mM_m8" /locus_tag="SSOG_RS55140" /protein_end="489" /protein_start="473" /score="17.4" /tool="antismash" /translation="MDAEYWFTNLRETVRF" aSDomain 36982..37482 /ASF="catalytic triad H,G,P found: False" /aSDomain="PKS_DH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55140_PKS_DH.1" /evalue="3.30E-62" /label="SSOG_RS55140_PKS_DH.1" /locus_tag="SSOG_RS55140" /protein_end="769" /protein_start="602" /score="201.7" /tool="antismash" /translation="HPLLGAAVRLAGSDDVVLTGRISRATHPWLEDHAVFGTVLLPGTA FVEMALRAADEVGCDALRDLTLHAPLALPEQGEIDIQVQIGAGTGTGRPLDIYSRPRRH DGTAEWTQHASAVLATDAVPADINGPLFGAAWPPAGAERLDAADHYDTMAAAGLEYGPA FQGL" CDS_motif 37066..37143 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0009" /evalue="3.80E-12" /label="PKSI-DH_m2" /locus_tag="SSOG_RS55140" /protein_end="656" /protein_start="630" /score="38.5" /tool="antismash" /translation="WLEDHAVFGTVLLPGTAFVEMALRAA" CDS_motif 37450..37482 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0010" /evalue="2.80E-03" /label="PKSI-DH_m3" /locus_tag="SSOG_RS55140" /protein_end="769" /protein_start="758" /score="10.6" /tool="antismash" /translation="GLEYGPAFQGL" aSDomain 38347..38715 /ASF="KR domain putatively catalyzing D-configuration product formation" /ASF="catalytic triad S,Y,N inconclusive" /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS55140_PKS_KR.1" /evalue="1.20E-35" /label="SSOG_RS55140_PKS_KR.1" /locus_tag="SSOG_RS55140" /protein_end="1180" /protein_start="1057" /score="115.1" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C1" /tool="antismash" /translation="GTVLITGGTSGLGAQVARHAARHGARHLLLLSRRGSAAEGAEALR DELAASGARVTVRACDVADRDQLERALRDVPDAYPLTAVVHAAGVLHDAVVESIDAYGL DAVLRPKTDAAWHLHELTA" CDS_motif 38350..38448 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS55140_0011" /evalue="5.70E-13" /label="PKSI-KR_m1" /locus_tag="SSOG_RS55140" /protein_end="1091" /protein_start="1058" /score="41.4" /tool="antismash" /translation="TVLITGGTSGLGAQVARHAARHGARHLLLLSRR" gap 38718..38817 /estimated_length=unknown gene <38818..42434 /locus_tag="SSOG_RS38170" /old_locus_tag="SSOG_07572" CDS <38822..42434 /NRPS_PKS="Domain: PP-binding (130-195). E-value: 9.4e-13. Score: 40.3. Matches aSDomain: nrpspksdomains_SSOG_RS38170_PP-binding.1" /NRPS_PKS="Domain: Condensation_LCL (237-502). E-value: 5.5e-32. Score: 102.9. Matches aSDomain: nrpspksdomains_SSOG_RS38170_Condensation_LCL.1" /NRPS_PKS="Domain: FkbH (854-984). E-value: 2.7e-38. Score: 123.0. Matches aSDomain: nrpspksdomains_SSOG_RS38170_FkbH.1" /codon_start=3 /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) Condensation" /gene_functions="biosynthetic-additional (smcogs) SMCOG1256: FkbH like protein" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012873.4" /locus_tag="SSOG_RS38170" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07572" /product="HAD-IIIC family phosphatase" /protein_id="WP_039939679.1" /sec_met_domain="PP-binding (E-value: 1.8e-08, bitscore: 33.8, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 3.1e-23, bitscore: 81.4, seeds: 42, tool: rule-based-clusters)" /transl_table=11 /translation="AFLDALAQQRRRTGRPGLSLAWGLWAEATGMTGHLGAADLERIKR GGVAALDTDQGLGLLDAALARDTDDALLLAAALDEPVLRATAPGLLPPLLAGLFPPRRR VAVARAGRAAGADGRMALDSRDAVVDRLRYRFAGTMGFDTTEIDPAAPLVGQGLDSVMA MQMRSLIESDFGQALPVGSLFNGASVESIADQLIAGAGRTVDGPDASGGTEDAEDIPDV VRHPATRDVVRLLRAEQHGTPGVTHHIGLAVRLTAPTTPDRLAEVIASLTARHAALRTA IVPDADGGLRLEVRRSLDDDLVRWSPVDEGTDVDERLRALMEPPFDLSLAPLWRFELLA YPSGEQVLVFGAHHAVSDLASLMLVAHGLGAGLGGAEPPAAVTNRDIDLLLRAQAERPA DEQGPSAAWREDFVGARRLDLELAGPRPVERSFRSAMHLADLPQDLHEKVAARANRLGI TPAAFWLGVLTVHLARLRERNRFVLAVPVDTRLHVSAPDAVGYFGLPIPYAAQVEAGEA AVDVLRRTDSRLSRVLERGVTFFDAMSALVEEGLYRKDAPLVEVYFNYMPPHAGAAEGL RIVPAGTGYSDLDLMVTVMPGLGKVGLEYNADVLDEANCADLARGCLALAAEIADGPDT LLALPEGPTTVAPEPATAIEPAVAPEPAQRIAVAATFALGNLPAMLSVALEDAGVDGGP FDVAEAPYHQVLASLHDPGSVLARTPTVASLVLLRPGDLTRFADTGDGGDLLAQLADEY PTALRALADRTRTPLVVAFLPERSDDERLRAWERQVTARLADRPGIAVLPSDTWNDDDY PVADVFDAHTDTMAHLPFQDEFQAVVALRLADVVWKVRRRAPKVIVVDGDETLWSGVAG EIGPGNVDLTGPRALLAQRLLQWREAGVLLALVSNNDEDTVHRILDRPDSPLHREHFAA ISAAWEPKWTRIVKIAEELRLGLDSFLFLDDNPVEIAGVRAQLPEVLCVTCPGAGELAD FVARLWPMVPRAATAEDSARAEFYRQEQVRGEARAHLGFAEFLENLQLELDIEPVSEET AERTVQLSRRTNQFNLRPRPLDAAGLERLREDGEVWTATARDRFGAYGQIGVLAVTADN DALEVVAWMMSCRVLGRGVEDRLLQWLADRAEAHGCGTVRLVADHTPRNIPARRLVSRL GGGDVEAPRLEVAVPVAQLREFRSWDLGSENAAEVSNA" aSDomain 39213..39407 /aSDomain="PP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38170_PP-binding.1" /evalue="9.40E-13" /label="SSOG_RS38170_PP-binding.1" /locus_tag="SSOG_RS38170" /protein_end="195" /protein_start="130" /score="40.3" /tool="antismash" /translation="RLRYRFAGTMGFDTTEIDPAAPLVGQGLDSVMAMQMRSLIESDFG QALPVGSLFNGASVESIADQ" aSDomain 39534..40328 /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38170_Condensation_LCL.1" /domain_subtypes="Condensation_LCL" /evalue="5.50E-32" /label="SSOG_RS38170_Condensation_LCL.1" /locus_tag="SSOG_RS38170" /protein_end="502" /protein_start="237" /score="102.9" /specificity="C activity: active" /specificity="Active site motif: HHAVSDL" /tool="antismash" /translation="EQHGTPGVTHHIGLAVRLTAPTTPDRLAEVIASLTARHAALRTAI VPDADGGLRLEVRRSLDDDLVRWSPVDEGTDVDERLRALMEPPFDLSLAPLWRFELLAY PSGEQVLVFGAHHAVSDLASLMLVAHGLGAGLGGAEPPAAVTNRDIDLLLRAQAERPAD EQGPSAAWREDFVGARRLDLELAGPRPVERSFRSAMHLADLPQDLHEKVAARANRLGIT PAAFWLGVLTVHLARLRERNRFVLAVPVDTRLHVSAPDAVGYF" aSModule 39534..41774 /domains="nrpspksdomains_SSOG_RS38170_Condensation_LCL.1" /domains="nrpspksdomains_SSOG_RS38170_FkbH.1" /incomplete /locus_tags="SSOG_RS38170" /tool="antismash" /type="nrps" CDS_motif 39564..39671 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38170_0001" /evalue="3.40E-07" /label="C2_DCL_024-062" /locus_tag="SSOG_RS38170" /protein_end="283" /protein_start="247" /score="22.6" /tool="antismash" /translation="HIGLAVRLTAPTTPDRLAEVIASLTARHAALRTAIV" aSDomain 41385..41774 /aSDomain="FkbH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38170_FkbH.1" /evalue="2.70E-38" /label="SSOG_RS38170_FkbH.1" /locus_tag="SSOG_RS38170" /protein_end="984" /protein_start="854" /score="123.0" /tool="antismash" /translation="KVIVVDGDETLWSGVAGEIGPGNVDLTGPRALLAQRLLQWREAGV LLALVSNNDEDTVHRILDRPDSPLHREHFAAISAAWEPKWTRIVKIAEELRLGLDSFLF LDDNPVEIAGVRAQLPEVLCVTCPGA" gene 42427..44829 /locus_tag="SSOG_RS38175" /old_locus_tag="SSOG_07573" CDS 42427..44829 /NRPS_PKS="Domain: PP-binding (68-130). E-value: 3.6e-11. Score: 35.2. Matches aSDomain: nrpspksdomains_SSOG_RS38175_PP-binding.1" /NRPS_PKS="Domain: TD (207-444). E-value: 9.7e-70. Score: 226.5. Matches aSDomain: nrpspksdomains_SSOG_RS38175_TD.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) RmlD_sub_bind" /gene_functions="biosynthetic-additional (rule-based-clusters) NAD_binding_4" /gene_functions="biosynthetic-additional (smcogs) SMCOG1010: NAD-dependent epimerase/dehydratase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014181759.1" /locus_tag="SSOG_RS38175" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07573" /product="thioester reductase domain-containing protein" /protein_id="WP_009719657.1" /sec_met_domain="PP-binding (E-value: 8.9e-09, bitscore: 34.8, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="RmlD_sub_bind (E-value: 2.9e-05, bitscore: 22.4, seeds: 37, tool: rule-based-clusters)" /sec_met_domain="NAD_binding_4 (E-value: 2.7e-58, bitscore: 196.1, seeds: 102, tool: rule-based-clusters)" /transl_table=11 /translation="MPEAGSGTSRNRSVNRRPEEEVIERRGPGRAQATDLLARFRKTAE RAAPEPAPADGAGARGVMEVAADIVARAARFLPGNTPDAETDLFDAGLSSVDAVELVAV MARELDVRVSLDDVFADARPRRLAQRWAAAAGLPTAVPDARPDAPSPSTPTTSSSNGSP SIAPVVVRASDGGADEDLEMILADLALADRLPFSHQADRVPPRRILLTGATGYLGSHLL LDLLRQRDAHVVCLVRAADDAAAERRLADALASFDQPWSSEVRRRVTVLAADLRQPRLG LSPEGWESLAQEIDAIVNVAAAVDFLRGYPSLRQTNVLGPLVLAELAMTGRPKPLHHIS SVAVFNEVGIEKMGEDDPVAHIDRLVAGYDKSKWAAEAVLRRAREHGLTVTFLRPGAIG GHTRTGVYNPRDLSTGLIGAFSRYRTVPAFKFMNLAPVDWISKVVAAVVFDPQAWGQNY NVTGRAETLPELVKDMKLAGMNVRVANWRDWRDDLLQRHAAEPVPELDFLVRILRSPTA MKLFEALMFGPEAGSERTETFVTRHRLPMAERYGGQAQLKAFERMAKDGVARLPSREDP PYLSFRERTKGHVGPIGEDRDTRCRMALTLSIASMYQVVRHRKIDVRGEVTCERLHPEP LTVEAGEIWVRPDEGVPLRHGSDHPLLRYRLVLVDRDGGRWWLEGWKTARASRDFWKQT RTIEVTIGREGEPAGLSGVVKVPGKSYVPDQIDGIRVDPRLSSQEQRLAKLAWLSWFFV QVGMGLAEPSLRVAAELLDLRRDAIDRDKDKLQRKIRKLMIKREQTR" aSDomain 42631..42816 /aSDomain="PP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38175_PP-binding.1" /evalue="3.60E-11" /label="SSOG_RS38175_PP-binding.1" /locus_tag="SSOG_RS38175" /protein_end="130" /protein_start="68" /score="35.2" /tool="antismash" /translation="IVARAARFLPGNTPDAETDLFDAGLSSVDAVELVAVMARELDVRV SLDDVFADARPRRLAQR" aSModule 42631..43758 /domains="nrpspksdomains_SSOG_RS38175_PP-binding.1" /domains="nrpspksdomains_SSOG_RS38175_TD.1" /final_module /incomplete /locus_tags="SSOG_RS38175" /tool="antismash" /type="unknown" aSDomain 43048..43758 /aSDomain="TD" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38175_TD.1" /evalue="9.70E-70" /label="SSOG_RS38175_TD.1" /locus_tag="SSOG_RS38175" /protein_end="444" /protein_start="207" /score="226.5" /tool="antismash" /translation="ILLTGATGYLGSHLLLDLLRQRDAHVVCLVRAADDAAAERRLADA LASFDQPWSSEVRRRVTVLAADLRQPRLGLSPEGWESLAQEIDAIVNVAAAVDFLRGYP SLRQTNVLGPLVLAELAMTGRPKPLHHISSVAVFNEVGIEKMGEDDPVAHIDRLVAGYD KSKWAAEAVLRRAREHGLTVTFLRPGAIGGHTRTGVYNPRDLSTGLIGAFSRYRTVPAF KFMNLAPVDWISKVV" CDS_motif 43051..43140 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38175_0001" /evalue="4.40E-03" /label="PKSI-KR_m1" /locus_tag="SSOG_RS38175" /protein_end="238" /protein_start="208" /score="9.7" /tool="antismash" /translation="LLTGATGYLGSHLLLDLLRQRDAHVVCLVR" gene 44826..45932 /locus_tag="SSOG_RS38180" /old_locus_tag="SSOG_07574" CDS 44826..45932 /NRPS_PKS="Domain: Abhydrolase_1 (41-162). E-value: 4.1e-11. Score: 34.9. Matches aSDomain: nrpspksdomains_SSOG_RS38180_Abhydrolase_1.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014181758.1" /locus_tag="SSOG_RS38180" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07574" /product="alpha/beta fold hydrolase" /protein_id="WP_009719658.1" /sec_met_domain="PF00561 (E-value: 1.3e-08, bitscore: 33.9, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-08, bitscore: 33.7, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MTLRPLHHALGDRVEEIPFTASDGTELGLCRVAPEDGATDRPAVL ILHGLTASADMFTLPETRNLVDVLLDAGYEPWLLDWRGSCRLPYNEGRVRYTFDDVALY DIPEAVSLIRERIDGRELLVVAHCIGAMCLSLSMAAGLVPGLAGVVAQGVFLTPKMSWK TRARLHFGGELLRSRLVNIPTDFKKVGLWSKHSLIFAEVSLGAECKDPNCQILNNDSWG VGGSLFEHDNLDDVTHDRLADLYGTVPMWILPHLRSIELAHTMMRYNDADGRYDALPKN ALDNAGKFDIPLMLLSGSDNRFWYDSNELCHDVLTRRYPEMDVRYVEVPGYGHLDTFIG RNAALDVFGHIVDFLDECRSVNATAVRE" aSDomain 44949..45311 /aSDomain="Abhydrolase_1" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38180_Abhydrolase_1.1" /evalue="4.10E-11" /label="SSOG_RS38180_Abhydrolase_1.1" /locus_tag="SSOG_RS38180" /protein_end="162" /protein_start="41" /score="34.9" /tool="antismash" /translation="PAVLILHGLTASADMFTLPETRNLVDVLLDAGYEPWLLDWRGSCR LPYNEGRVRYTFDDVALYDIPEAVSLIRERIDGRELLVVAHCIGAMCLSLSMAAGLVPG LAGVVAQGVFLTPKMSW" gene 45946..47421 /locus_tag="SSOG_RS38185" /old_locus_tag="SSOG_07575" CDS 45946..47421 /codon_start=1 /gene_functions="transport (smcogs) SMCOG1005: Drug resistance transporter, EmrB/QacA" /gene_kind="transport" /inference="COORDINATES: protein motif:HMM:NF019310.4" /locus_tag="SSOG_RS38185" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07575" /product="MFS transporter" /protein_id="WP_009719659.1" /transl_table=11 /translation="MTSEIEQSGAAPSGARLVMPIILLTIFTVPLSISGTAVSLGDIAD DLGSSSTGEQWALNGYTLTFACSTLIWGSIADIIGRWRALMSGLVIFGVGSAMSLVAAN YLVLDVARLVAGAGAGAVFSVGTAVVSSNFEGERRTRAFALLGSVAGLSLAFGPSLCGL FTQVVGWRFVYGFQLGCLVIACLGMPLIRRAAAHEKRYAARIDVAGAVLFCVATTLTLG GLALGSATGWLSLPFLLCTAAGFVAYGLFAWRESTAPSPLLSLRTLRNKRFSGMTLVVA VSSFTFTNAVAYLPVFFQGAYGSSPGASGAFLMFLTMPVLISPLIAGRLAARGTAVDTI LIWSIALMVVGLVATGAVAEQGLAWMTFPMVVVGAGFGLQAGLIDGEALAQVPAKEAGM AAGWINTVRLGSEAIAVSLFGSLFASFAGNADHASRQGFAGITIGSTLFAAVIGLLSIL LLRRGRQSETPPREQRLIARGSGPAPRRGARSE" gene complement(47369..48292) /locus_tag="SSOG_RS38190" /old_locus_tag="SSOG_07576" CDS complement(47369..48292) /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_function="GO:0043565 - sequence-specific DNA binding [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1287: AraC family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009719137.1" /locus_tag="SSOG_RS38190" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07576" /product="AraC family transcriptional regulator" /protein_id="WP_009719660.1" /transl_table=11 /translation="MDVLSELLDGVRARGALFQRTVMNRPWSLRFASGSPLTLATMLRG RAWIVPENGEPVPVGPGDIAILRGRAPYTVADDPATPPQTVITSADYCVRDADKNETAE DPDGSALLLSGAYTGRGEISERLLHALPDVTVLPDADCHRPLRDLVIEEIARDRPGQQA MRDRLLDLMLLSTLRTWFDQSEAHAPPWYRAMDDPAVSHALQLLHDDPAHPWTVASLAA TSGVSRAALARRFTAQVGEPPMTYLASWRVDVAADLLRETDATVGSIARKVGYANTFAL SVAFKRLRGITPTEHRAAAQAPSPGR" gene 48373..49209 /locus_tag="SSOG_RS38195" /old_locus_tag="SSOG_07577" CDS 48373..49209 /codon_start=1 /gene_functions="other (smcogs) SMCOG1199: NmrA family protein" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020549460.1" /locus_tag="SSOG_RS38195" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07577" /product="NAD(P)H-binding protein" /protein_id="WP_039939681.1" /transl_table=11 /translation="MTKHPILVTGGTGKTGGRVVSRLRAQGAPVRVASRSGEPPFDWFD RATWDAALDGVKAVYLVPIDGELLTRPFIERAVELGVERVVLLSGRGVDVPGYSGEANI AGATHVDGETAVLDSGIAWTILRPAWFAQNFSEGSFLDAILAGELRLPAGDGAASFVDA EDIAAVAAAALTEDGHGGQIYELSGPRALTIADAVAEISGATGRDIRYVPLTPEEFVAE LTGQGWSSAEAEDYAEAVSPIRRGMDSHLSDGVRRALGRQPRDFTDYVKASVKAWP" gene complement(49193..50095) /locus_tag="SSOG_RS38200" /old_locus_tag="SSOG_07578" CDS complement(49193..50095) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1014: LysR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014669745.1" /locus_tag="SSOG_RS38200" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07578" /product="LysR family transcriptional regulator" /protein_id="WP_009719662.1" /transl_table=11 /translation="MLDVRRILLFTEVARRGSVTATARALNYTPSAVSQQVSRLETEAG QPLLERHARGVTLTDAGRALALRGERIERELTAAENELADFAGLRAGTLRIGTFPTVGA SLLPRAVIAFREAHPDVRLTVRSARIAGLWAMLENREVEMSLMWDYDWNRIDREDIVVT SLADDPPALLVSKDHPLADRPMAALADFANDPWITRADHHPVAEALARSCHTAGFEPQI AYEAHDYQEAQAMVAAGIGVALAPTLALEGIRGGVSVLPLQPPAPVRRILLVRMADHAL TPAAQSFAGFLRDSATATP" gene 50228..51346 /locus_tag="SSOG_RS38205" /old_locus_tag="SSOG_07579" CDS 50228..51346 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020134905.1" /locus_tag="SSOG_RS38205" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07579" /product="PrpF domain-containing protein" /protein_id="WP_009719663.1" /transl_table=11 /translation="MLRLQGEMIRGGTSKCWIFDHHDVVATGVDADTLLLAAYNAADPR QIDGVGGASSTTSKAAIVQASAEPGVDVEYAFAQVGIGDERVEWTSNCGNCATAVALYA VHNGLVPITPDTTTVRMLNVNTGARLTGTIPTPGSTAPHEGTAGVPGTAALGVPVLLGF EDPAGTTTGRALPTGRALDTLTGPAGPVEASLIDAGAPAALFEAKAFGLDGTESLTEFA AAVPALTALRREAALAMSLADQGEPVSHAVPKVGVVARSVSYHTTHGTLVAPDEYDLAV RMVSMHAPHPAIGLTSAVALATAAAIPGTLAHRVARQTADGTLRLGTPAGVITAQAVPA TNGACPTVLLHRAARRIARAELLVPVLEGRPA" gene 51343..52752 /gene="dctA" /locus_tag="SSOG_RS38210" /old_locus_tag="SSOG_07580" CDS 51343..52752 /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0015293 - symporter activity [Evidence IEA]" /GO_process="GO:0006835 - dicarboxylic acid transport [Evidence IEA]" /codon_start=1 /gene="dctA" /gene_functions="transport (smcogs) SMCOG1212: sodium:dicarboxylate symporter" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020134904.1" /locus_tag="SSOG_RS38210" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07580" /product="C4-dicarboxylate transporter DctA" /protein_id="WP_009719664.1" /transl_table=11 /translation="MSRNDAAPGTVTAPPHRIRRLLSLLYVQCLVGVVAGAAVGWLWPS FGADLKPLGDGFIALVRMMIAPIIFCTVVHGIASMGNARAVGRVSLKALLYFEVLTTVA MVIGLVVVNVVQPGSGLHVDTSTLSTEGLPPEATASHESFAGFVLAMIPDTLLSALTGH EILPVLVISVLFGFGLHASGEAGLGIARGIEKLSKVLFTLIRWVMRLAPLGAFGSMAFT IGNYGLDTLRHLFLLVGSFWLTALFFVLVVLGTVMRLNGLRLLPFLRYIREELLIVLGT SSTEPVLPRMMGKLQHVGASKPVVGITLPAGYSFNLDGTAIYLTMGSVFLAQALGIDLS LTQQLSMLAVMLLTSKGAAGVTGSGFIALAATLSAVPHVPVAALALIFGIDRFMSEARA LTSLVGNGVATLAVAKWEGQLDEDRAKAVLRGDIPYPSGPEAGPVPGEKPVDDGPKATA GTDRDPVAAVG" gene complement(52749..53093) /locus_tag="SSOG_RS38215" /old_locus_tag="SSOG_07581" CDS complement(52749..53093) /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020127220.1" /locus_tag="SSOG_RS38215" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07581" /product="helix-turn-helix transcriptional regulator" /protein_id="WP_009719665.1" /transl_table=11 /translation="MASQATGSGHRAAPVHTDPAEVSVLTALSALADPVRIQLVRELAG SAEWTRSCGSFDVSVGKAALSHHFSVLRGAGLVEQRDQGPRRVNRLRREEFDARFPGLL DLVLRPDGSP" misc_feature 53193..53211 /note="TFBS match to HgtR, Hydrogen-dependent regulator, confidence: weak, score: 20.41" /tool="antismash" gene 53207..54184 /locus_tag="SSOG_RS38220" /old_locus_tag="SSOG_07582" CDS 53207..54184 /NRPS_PKS="Domain: PKS_ER (14-321). E-value: 1.8e-62. Score: 203.2. Matches aSDomain: nrpspksdomains_SSOG_RS38220_PKS_ER.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) ADH_N" /gene_functions="biosynthetic-additional (rule-based-clusters) ADH_zinc_N" /gene_functions="biosynthetic-additional (smcogs) SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018543394.1" /locus_tag="SSOG_RS38220" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07582" /product="zinc-binding dehydrogenase" /protein_id="WP_009719666.1" /sec_met_domain="ADH_N (E-value: 4.8e-09, bitscore: 35.2, seeds: 66, tool: rule-based-clusters)" /sec_met_domain="ADH_zinc_N (E-value: 1.5e-23, bitscore: 82.3, seeds: 86, tool: rule-based-clusters)" /transl_table=11 /translation="MRTVAFQEYGGPEVLQVVRAEPPEPGPGQVTIDVAYAGVNFADLK ARAEGYRVASLPYVPGLEVSGRIRAVGPGVEGLRPGQDVAALVGGGAYAEVVAAEAATV FPLPEGLDLRTAATLPTVLPTAHALLHEVGRLRAGESVLVHGAAGGVGTVAGQLARAAG AGAVYGVVSSAAKAGHALEHGYDEVFTTDTFPGDVHRATGGRGVDLVLDPVGGDTLRRG LDALAVFGRLVSFGNASGAEPWHAGQADLAARGRSVAGFSILALAQTAPEALRSLTERA FRTATDGTVTLPVTAEFPLADAAEAHRLMGGRTSTGKLLLRMAD" aSDomain 53249..54169 /ASF="ER configuration inconclusive" /aSDomain="PKS_ER" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS38220_PKS_ER.1" /evalue="1.80E-62" /label="SSOG_RS38220_PKS_ER.1" /locus_tag="SSOG_RS38220" /protein_end="321" /protein_start="14" /score="203.2" /tool="antismash" /translation="LQVVRAEPPEPGPGQVTIDVAYAGVNFADLKARAEGYRVASLPYV PGLEVSGRIRAVGPGVEGLRPGQDVAALVGGGAYAEVVAAEAATVFPLPEGLDLRTAAT LPTVLPTAHALLHEVGRLRAGESVLVHGAAGGVGTVAGQLARAAGAGAVYGVVSSAAKA GHALEHGYDEVFTTDTFPGDVHRATGGRGVDLVLDPVGGDTLRRGLDALAVFGRLVSFG NASGAEPWHAGQADLAARGRSVAGFSILALAQTAPEALRSLTERAFRTATDGTVTLPVT AEFPLADAAEAHRLMGGRTSTGKLLL" CDS_motif 53621..53683 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38220_0001" /evalue="1.20E-06" /label="PKSI-ER_m5" /locus_tag="SSOG_RS38220" /protein_end="159" /protein_start="138" /score="21.0" /tool="antismash" /translation="GESVLVHGAAGGVGTVAGQLA" CDS_motif 53810..53842 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS38220_0002" /evalue="9.30E-04" /label="PKSI-ER_m7" /locus_tag="SSOG_RS38220" /protein_end="212" /protein_start="201" /score="11.9" /tool="antismash" /translation="TGGRGVDLVLD" gene 54227..55186 /locus_tag="SSOG_RS38225" /old_locus_tag="SSOG_07583" CDS 54227..55186 /GO_component="GO:0016020 - membrane [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1166: transporter, EamA family" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018093179.1" /locus_tag="SSOG_RS38225" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07583" /product="EamA family transporter" /protein_id="WP_009719667.1" /transl_table=11 /translation="MTDSSVTRGFTRVAGNIPAPALVLGGVCGIQFGAAFSPQIYPQVG APGVVFLRLLIAGVLLCLVWRPRRQALDSVKGAWGTVIGAGALLAGHHLAFYEAVNHIP LGAVATIEFLGPFAIALAGSRRAVDLLPACLAAAGVLLLGGGGVPLDPGGLALAAVAAC CWGGYILVSSRMARRLSGGQGLALAVLWAALLSTPYGLVRAGSAVLDPHVLWVAAVVAV ASSVLPYSLNLEALRRIPPRVFGVLTSLEPAAGALFGLLILGQRLAWPQWLGIAAVACA SVIATFLGAGGRRNSRVRAKSASPDAGQPALCETGPAR" gene 55750..56535 /locus_tag="SSOG_RS38230" /old_locus_tag="SSOG_07584" CDS 55750..56535 /EC_number="3.5.2.9" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]" /GO_function="GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing) activity [Evidence IEA]" /GO_process="GO:0005975 - carbohydrate metabolic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020684231.1" /locus_tag="SSOG_RS38230" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07584" /product="5-oxoprolinase subunit PxpA" /protein_id="WP_039939684.1" /transl_table=11 /translation="MPVVDLVADLGESFGAYTMGNDAELLDLLTSANVACGFHAGDPRV MDATVRSCVERGVGVGAHPSFPDLVGFGRRAMDLAPNEVRTDVLYQIGALSAFTCAHGT RINHLAPHGRLGNLVVVRRDYAEAVADAVEAFDPSLVILMQEGEMAAVARERGLRMAMV GIADRAYEDDGTLVSRSEPGAVLHDPDEVTRRTIRMVTEGVITSRHGTDLPVRTDCVQL HGDGPAALELARRIRGELLEAGVGLAPLDEVLDARAQAA" gene 56546..57289 /locus_tag="SSOG_RS38235" /old_locus_tag="SSOG_07585" CDS 56546..57289 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF014712.4" /locus_tag="SSOG_RS38235" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07585" /product="carboxyltransferase domain-containing protein" /protein_id="WP_009719669.1" /transl_table=11 /translation="MTVMRTTAKIDISPCGDAALRVTVDGDDTDVVWAAVHRLAGWLNR GDIHPTVSAVPTYDAVLVEFDPYHTTGDAIMSYIRSWDAAPDVASAVPSGVIDVPVLFG GDAGPDLEWVAGVVGASVAEVVRLVCAKEHLIRCLGGPAASAMTDGPEFGVPVPRLATP RLRVPPGAISVAGRQAVIGPVAAPSGWRQIGRTPLTILRTDGSGHTGSDSVVPYRPGDR VRFFPVDEGTYAALLGVPMRYRNHD" gene 57282..58253 /locus_tag="SSOG_RS38240" /old_locus_tag="SSOG_07586" CDS 57282..58253 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF014663.4" /locus_tag="SSOG_RS38240" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_07586" /product="biotin-dependent carboxyltransferase family protein" /protein_id="WP_050800090.1" /transl_table=11 /translation="MTDRPELSVEAATACVVTDLGRTSGPARGLAVNGALDQFAARAAN ALVGNAPTAPLIEATGFGVTLRPSHDILLAVTGAPAEPAVDGLPHPAWSPLSVRAGETV RVGISDAGLRAYVAVHGSFDVPMLMGSCAPDSMIEFGTPVTAGMSLTLHRSHPPLVNRR FGATVFDFGIPRDIGRVPAVLDVIEGPDAAEFGTGLQRLFDSPYTVTPRINHVGLRVAG HVPQRTVTGEVLSRGVPVGAVEAPAGDELLVLMRGRGITAGYPVLAVLTSRALDVAAQL RPGQEIRFRRTSATAATAAYLERRRLLDRVALRARTAFAALS" ORIGIN 1 gacccgcccg gtcaccgccg gataccccac cgtcaccgcc aagttcagcg acgccctgaa 61 cgcgatatac ggcggcgccg acccgaaggg cgccctggag aaggccgcac gcgccatcga 121 ccgggacttc tccgacaacg ccggttacaa gatcccgtag tcccgtaacc ccgtcatccc 181 gtaggacgct tcggccgggg cgggaccgct cacgacgcgc aggacgcgta cggcggcacg 241 cccgtcccgg ccgggaacag gacaccccgt gaagaccgtg gaacccgcgc ccgccgcgcc 301 ctcgaggagg gagcagggcc cgcccgtgaa ccccgtgaag cgcgcgcggc cggtgcgtac 361 gaaccgagac tgggcgcacg gactgctcat gtccgcgccc gccgtcgccg gactcatcgc 421 cttcgtcggc atcccgttcg gctacgccgt cgtcctctcc ttctacaacg tgcgcctcgg 481 ctccccgctg gagcccacct tcttcgggat cgagcagtac cggcgcctgt tcaccgaccc 541 ggacctgtcc ggcccgttcc tgcgggccct gctcaacaac ctcaccttcg ccgtggtcgt 601 cgtaccgctc cagacgggcc tggcgctggg cctggccatc ctgctcaacc gcaagctgaa 661 ggggatcggc ctgttccggt cgctgttctt catgccggtc gtcttcccca tggccctggt 721 cgccgtgatc tggcggctca tcctcgcccg cagcgacgag ggtctgctca actccgcgct 781 gcacgcggtg agcttcggca actggggcgc cttcgactgg ctcggcgacg gcgccaccgc 841 gatggcctcg atcatcgtgc tgtcggtgtg gcagggcgtc ggcttccaga tggtcatcct 901 gctcgccggg ctccagcaga tccccggcga gctctacgag gccgccgaac tcgaccgggc 961 cccccggtgg cagcagttcc gccacgtcac cctgcccggc atccgcggca ccctcgtctt 1021 cgtcgccatg ctgacctccg tgctgtcctt ccgggtcttc gaccaggtct acgtcctcat 1081 tcacggcgga ggtctcgacg aggacgccac ccgcacggtc atgtaccagg ccgtcaccac 1141 cgccttcgac cagaacaaca tcggccaggc gtccgcgatc acggtcgtct tcttcctgat 1201 cgtcgtcgcc ctgaccctca tccagcgccg cctcgtccgg cccgacaacg aggactgacc 1261 cacgatggcc acgacccgcg cacccctgcg ccgtttcgcc gactacgccg tcctcggtat 1321 cctggcgttc atcttcgtgc tgcccgtcct gtacctgctc ctgggcagcc tcaagccctc 1381 ggacgaggtg ctgaacggtc tgaccggctt cctccccacc cacttgtcct tcgacaacta 1441 cgcggccgtc ctggacgccc tcaactccga cagcaccggc tacttctggc gcttcatggg 1501 catctcgctg ctcgtcgcgt tcgtggtcgt gaccggcggc ctcttcgtca actcgatggc 1561 cgcgtacggc atgtcacggc tgaagtggcg cggccgggag gccgtcttca cgctcgtgct 1621 gctgctgatg ctggtcccgt tcgagtcggt ggccgtgccg ctcttctaca tgttcaacga 1681 ccagcgcgac accatcttca tccaggcggt cccgttcatc gccaacgcct tctcgatcta 1741 ccagttccac accttcttcc gctcgatccc gccgagcatc gaggaggccg cccggctgga 1801 cggtgcgggc ccctggcgca cgttcttcgc ggtcatcgtg ccgatgtcga agccggtgtt 1861 cgcctcggtc gcgatcctca ccttcctcat gcagtggggc tcgttcctct ggccggtcct 1921 gatggtctcc gacccctccg tccgccccct ccccctggag atgagcgtct tccaaggcca 1981 gcaacccccg gactggggcc agatcctcgc cttcggcgtc ctcctcgtcc tgcccgtcct 2041 gatcgtcttc gccttcttcc agcgctggtt cgtccagggt gtcgccagct ccgccgtcaa 2101 gggctgacca ctgagaggca cggcggactg gtccagacca aactcttgac agggtttccc 2161 ttcacttctt aaatcacgta gtgaactgag tatctgtcat gttccgctca ccccccactc 2221 cggacgtctg gaagggagag tcatggactc cccgcgtctg ccccggcgat tactgctgtc 2281 cttcgcctcg gttctcgccc tcatgtcgct gtccaccgga ctggcgcagg gtgcgcccgt 2341 ttccgccgtg gatcccgccg cgccaccggc ggctgccgcc gccgtcacgt tctccgacga 2401 gttcgacggg cccgcgggct ccgccgtcga cggcggcaag tggcagatcg agacgggaga 2461 caacgtcaac aaccatgagc ggcagtacta cacggcaggc aaccgcaacg ccgccctcga 2521 cggacagggc catctggtca tcaccgcccg ccgcgagaac cccggcaact accagtgctg 2581 gtacggaaga tgcgagtaca cctccgcccg gctgaacacg tccggcaagt tcaccaccac 2641 gtacggccgg gtcgaggccc ggatgaaggt tccgcgcggg cagggcatgt ggccggcgtt 2701 ctggatgctc ggcaacgaca tcggacaggt cggctggccc aactcgggtg agatcgacat 2761 catggagaac gtgggcttcg agccgtccac cgtccacggc accctccacg gccccggata 2821 ctcggggtcc ggcggcatcg gcgccgggta caccctgccc ggcggccagg cgttcgccga 2881 cgccttccac accttcgccg tcgactggag cccgaacgcg atcacctggt ccgtcgacgg 2941 aaccgtgtac cagcggcgca cccccgccga cctcggcgga cggcagtggg cgttcaacaa 3001 gcccttcttc ctgatcctca acctcgcggt cggcggctac tggcccgggg acccagacgg 3061 cagcacggcc ttcccccagc agctcctcgt cgactacgtc cgggtcagca ccgacagcgc 3121 acaaccgggc ggcggcgcca tcaccggcgt cggcggcaaa tgcgtggacg tggcgggcgc 3181 cgacaacgcc aacggcacgc ccgtacagct ctatgactgc aacggctcgg ccgcacagca 3241 gtggaccgtc ggcagcgacg gcacgatccg cgcgctgggc aagtgtctgg acgtggcatc 3301 gggcggcacg gccgacggca ccccggtcca gctctacgac tgcaatggca gcgcggccca 3361 gcagtgggcc gtccccgcgg cccgcgacat cgtcaacccg caggccgaca agtgcctgga 3421 cgccaccggc ggcggttcgg ccaacggcac ccggctccag atatggacct gcaccggcgc 3481 cgccaaccag aagtggacgg tgacccggta accacgcggc gccaccgacg acagccggac 3541 cgttccgaag tgcgggacgg gaacacggcg actgggatgt cagggatagc gtccctctca 3601 caccggacaa gtgaggggga catcgtgagg tttcaggtgc gtgggcgggg tggccgccgg 3661 tgggtcccgt tcgtggtgat cgcgttcggg gcgctgttct tggccatcgg gctgatcctc 3721 gcgggggtgt cggcgtcgtt cctgacggac gcgaagcgtg cccgggggac ggtggtgtcc 3781 ttggagtggc ggaacgacca cgagacctcc cccaggacgc agacggacga caagcccgcg 3841 gcgtacccgg tggtcgcgtt cacctcggcg gacggcgcgc cgaggaagtt cgaggactcc 3901 acggggtcca acccaccgtc gtacgagctg ggtgagcggg tcgaggtgct ctacgccccg 3961 ggttcccccg aggacgcgcg gatcaacggg ttcgcctcgc tgtggctgat gccgctgatc 4021 ttcggtggga tcgggttcgt gatcgcaggg atcgggacag gggttgcggt ggcgacgcga 4081 cgacgttcct aggccgcgta ctgtcggccc cgtgccccgc cacccgaaga agccccgccg 4141 cttggtcgcc gaagggcgcg cgtacctgtg gacgctccgc cacagccacc gcgtgctgga 4201 cagcggccgg gccgcggact gccgcgagac cctcacgctg tacccccaac cgcccggcac 4261 cggcggcccg ctgcgcatcg tcttcgccga cggcccgggc cggtacgtcc cgggcgggtt 4321 cccgctgggc tccggggacg tgggatacgt ccggggcggc tccctgaacc tgcacgaacc 4381 gggcgccgtc cgggccctgc tcgacgcggc gtcggcccgc ggatggcagc cgggggaccg 4441 gcgggcggcg gaggtcgacg gctggcccct gctggaggcg gcggtggcgg cgcgagccgg 4501 tgacgtcggc ccgcacgggc cgtagggggt ggctccggca tcccctcact ttcccgggaa 4561 tcgggggcac acttgactgg gggtcaaggg ggcgcaggtt caaatcctgt cgtcccgacg 4621 gtgcgggaag gcccgctggc agggagaaac cccgggccag cgggcctttc gttgatcctt 4681 cgcgaccgag tacgcgcggg cccactggcc cgggcgggtg gcgaagaccc gggacgaggt 4741 cagcgacgcg ctgacagctg tcacagtggc gatgctgtgg gaccttcctg gccggccgaa 4801 cgggcagctg ctgcgtcgtg ccctgcggca ctgggcgttc ctcgtgcctg ggccggggga 4861 ggtgccggcg gaggaccggc tggtcctgca gtgggtggcg aaggcgtccc ggccccctgg 4921 tgcacctgca cgatccggtc ctggtgcgcg atgtgctgga gtcgctgcgc cgccgtatga 4981 cttgtggcac tcggcgctgt ccacctggct gtgtgcggac gcggacccag ctgaggttgc 5041 ccagcgcgcc ggtaacagtg tcgcgctcct gctgagccgg tacgcgaagt gcctgtctgg 5101 tccgagaagc gcagccccgc ggtgaggtgc cgggtcagac cttgattacg gtggcccgtc 5161 cgccgcacag cacggtcaga tcttcgggat ccgaggtgag gatggcgacc agtacgggcg 5221 tggcgagggc gatggcgctg agcatggcgt tgatggcgta cgtgtggccg tgcaggccgg 5281 cgtcggcgag gagcgcggca gcgtggcgtg cgatcggctc ggtgacaggt tcgacgacca 5341 ggcgcgacag agtcactcca gggccgggcg gttgatccgg gggcgggccg cctctaccag 5401 ggtggcgcct gacgtggtcg gtccacgtat gaccacggct ttgcgcatgt catacccctg 5461 attggctgag tccccgttca tgacctcata tagtgaaccc tttgccatgc gttcgttcgg 5521 tcgaaagggg gaggcgtcgc atgggcagcg gcagcggcgg cggcagggtc ctggacatca 5581 aggtggcgga catcaagtcc gtgtcgccga cgttccatca ccaggcggtc aagctgagtg 5641 aggcgctgac cacgctgatc aatacgctgg acggctatgg cgggccgtgg ggggacgaca 5701 agccgggcaa ggacttcgcg aagcactaca agccgaacca gaagcacatc gagtcggcga 5761 ccggcgtcct cgtcctcggc ctgaccagca tccacgaggc gatgcaggac atggccgacg 5821 gccacgtcga caacgacaag ctgatcgagg gcatgttcac caaggcgaag aacgcgcctg 5881 gcaaggacgg ccacaagtga gcatcggtag cacggtcgag gagaaggcca aggcaattct 5941 gctgtagctg ggcatgtggt ggccggacgc caactccggc accctgcgcc acgccgccga 6001 cgcctggcgg accttcgctg acacggtgga tgacgtgcgc gccgcgacca acaaggccgc 6061 caccacgctc atccacaaca acaagggcga ggcgatcgac gccttcgaga ccttctgggg 6121 gcgttatgcc aagggcaagg acgagggctg gctgagcgac ctggccacgt ccgcccgcag 6181 tatggccaag gcgctggaca agttcgccga caaggtcgat gaggcgatcg aggagctgtg 6241 gacgcagatc gccatcgatg ccgtggcgat tgtcgccggc gggctgctga ccctgccgac 6301 cgggggcgct tccgacgcgg tcgccgggga gatcatcgcg atggcggcgg gcctgggtgt 6361 cgcggtggag ggggcggtgg ccaccatcgc cgcggagatg ctggtcggcg ccgtgtacac 6421 cagcatcgcg tcggtcaccg tcgatctcgc cgtcgcgcag ccggccaaga tcgccctcgg 6481 tcagcagggt gggttcagcc tggatgaggt gaacgccgcc gccaaggacg gcatgatcta 6541 cgggggcctc ttcggcgccg gggcgggtgt gctcaagccc ggcgtgctcc ccaagaccgg 6601 cggcgttccc ggcttgttga agccgcccgg gatccgcccc aacctcattg ggaagggccc 6661 cgccggtcgt tttgccaagg agactccgaa ggtgggcgaa cccattgaca tcgcgacggg 6721 cgcgatgctg atggagcaga ccgacctcac gctccccggc tccctgccgc tggtcttcga 6781 acgcacccat atgtcgtcct accggggcgg cgtcagcttc ggcccgacct ggtcctgtct 6841 gctggacgag cgcatccagc tcgactccga gggcgtcgtc ttcgccgccg ccgatggcat 6901 gcggctggtg tacccggtgc cggagcccga cgttcccacc ctgccggaga agggcgcgcg 6961 ctggccgctg gagtgggacg ggaagccgga cggcgtcatg accgtcaccg acccggggac 7021 cggtgtcgta cggaccttca cccgccccgc cccgacggag gagtccagcg cggtccacct 7081 gtggctggaa agcctccagg accgcaacgg cacacgcatc gacatcgaac gcgccctggc 7141 aggcaacccc ctggcgatcc gccactccgg cggctactac gtggccgtcg acaccgacga 7201 gcaccggcgc gttaccgccc tgcgcctgct cgacgaggcg ccctcgatct acgagcccca 7261 gggccgcgac ggtgccggca cgatggtgat gcgctacgcg tacgacgagg ccggtcacct 7321 cgccgaggtc atcaactcca gcaaccagcc gatgcgctac acctacgacg cgcagggccg 7381 ggtcacatcc tggaccgacc gcaacggcac gtcgttcgcg tacgtctacg gcccggacgg 7441 ccgggtgatc cgcaccgagg gcagcgacgg cgtctacaac ggcaccctcg aatacgacga 7501 cgccgcgcgc accaccgtct acaccgactc cctcggccac cgcaccacct accgctacaa 7561 caccgacggc caggtgaccg aggagaccga cccgctcggc cacaccaccc tcaccacgtg 7621 gaacacccga ggcgaccgcc gcctctcggt caccgacccc atgggtcaca ccacccgcta 7681 cgcctacgac gaggacggca acctcaccgc tgtcaccctc cccgacggca gcgaggcccg 7741 ggccacgtac aacgatctct gccagcctgt ggaggtcacc gaaccgggcg gcaccacctg 7801 gcgccacgtc tacgacgggg ccggaaatct cctcaccacc accgacccca tggggtcgac 7861 ctccacttac ggctacaccg agcggggcca cttggccgag gtgacggacg cgctgggcag 7921 caccacgcgc ctgaccccgg accggaccgg gctccccaac gccgtaacgg acccgctggg 7981 acacaccacg agcgtccgcc gggacccctt cggccgggtg gtggaggcga cggatccgtt 8041 gggccgcaca acccgtatgg gctggacgac cgagggcaaa ccggggtggc gggaggagcc 8101 ggacggcgcc cgggagagct ggacctggga cggcgagggt aacctcctca cccacacggg 8161 cccggcaggc aacaccaccc accagacgtc cacccacttc gacgtccccg ccacccgcac 8221 ggagcccgac ggcgcgagct acgccttcgc ctacgacacc gagctgcgcc tgacccaggt 8281 caccaacccc cagggcctga cctggacgta cacctacgac ccggcgggcc gcctcaccgc 8341 cgagaccgac ttcaacggcc gcaccctcac ctacacccac gacgcggcgg gcgacctgcg 8401 gacccgcacc aacggcgcgg gcgaaaccct ccacttcacc cgggacgtgc tgggccgcac 8461 gacggaacaa cgcgatgagt ccggcgcacg gacgacatat gcctacgacg cgcagggcac 8521 cctgacccaa gcgacgaatc cggacgtcga actgaccctc gaacgggacg cggtgggccg 8581 agtcctgtca gaaacggtca acggtcggac gacgacgtac gcgtatgacg ccgcaggccg 8641 ccgtatcgaa cgcacgacgc cctcgggcct gaggagtgtc tggacctacg acgagtcagg 8701 ccgccccgcc caactgacca cgggcacggc cggcaccctg accttcacgt acgacgctgc 8761 gggccgcgag acggaacgcc gcatcggcga gtccgtgacg ctgacgcaga cctgggacag 8821 ggcagaccgc ctcgccaccc aaacgatcaa cgcaggccac cgccgcgaga cgggccggat 8881 cctccaacac cgctcctacg cctaccgcct ggacggctac ctcgccgaga tccgcgaact 8941 cacctcgggc acgcgccgct tcgacctcga ctcggtcggc cgcgtcaccg ccgtgcatgc 9001 gcacggctgg accgagacgt acgcctacga cacggcgggc aacctcaccc acgccacggc 9061 cccggatcac gaaacccccg gcgaccgctc cttcaccggc acgatcatcc accgcgcggg 9121 ccgcaccacc tacgaacacg acgcccaggg ccgcctcacc cgccgcaccc gcaaactcct 9181 caacggccag acccgcacct ggacctacac ctggaacccc gaagaccgcc tgacgaacgc 9241 gaccaccccc gacggcgagc actggcacta cacgtacgac cccctcggac gccgcatatc 9301 caaacaacgc ctggccgcgg acggcacggt ggcggaatcg gtgaccttcg catgggaaga 9361 cacccgcctc gcggagcaat ccacaccaga gggcaagcac accacctggg actacgcccc 9421 agacacccac cgccccctga cccaaaccga ccacacgtca ctggtgcgcg agcccggcct 9481 ggcaacaccg caccaccctc tggggcacgg acttcccctc cccagtaagc ccggaggccg 9541 ttgactgccc tctccgcttc cccggccaat acgcggacgc agaaacgggg ttgcactaca 9601 actatcaccg ccattacgac gccgagacgg cccgctacat cacccccgat cctctaggca 9661 tcgaaccggc gctaaatgac tatgcgtatg ttgctgatcc gctcagctgg attgacccgc 9721 tgggcctggc gggatgcaaa gctggaaagg tcaattgggt tacagagggt acaacccgat 9781 cggcagccgc agatgcgtat gaatctggcg cacatggggc tcgaagtgag gtttcctcac 9841 agaagaggct tgtcccttcg cttgattatg taaaagcaga cggcactcct ggggcggttc 9901 gcttcgatgg gctccgcgat ggccagttga tcgatcggaa actcggtgtc gctaccactc 9961 ccaagtcgaa gctgggccgc gaccaggcaa tccatggctc tcgaccagaa cgggcgaaca 10021 gctgtctggg aggtggcgga tcaacgtgcg taccggcggg ctactagaat gctcgggcag 10081 cagaacatca tcaatatcaa ggtgaggata gtttcgccat gaatgccatc attgctcgcg 10141 cgctgatcga gctgcttgta tcccttgagc tgtccgacga agagtctgtc tccgtggagg 10201 cgtcggcggc tcttgccgag gatgccgcca cgtcgctagg ggctctgtcg gataccgagc 10261 gagcggaact catctcgatc attacccaga tggctgaaga agccggggac gaggatcgtc 10321 ggcaagttct cctggacctc cctgaagggc ttggccttac cgagtgacca atgtgctcga 10381 cctttgtgaa tgcatcccgg catcgtcagc tcggcgcgcc ccaggcggcg gtgggatctc 10441 tgccgtcgcg ccgagtaccc gcacgcgccg ggtgagttgg tggcgcaggg ctccacccat 10501 gctggtgtgg gggaggctgg gtcggcgcgt acaacgctat cggtgcggcc ccacctgcac 10561 ggcgcaggcg atcacctggc tcgcatagcc ccttcggtcg agggagggca gtcaagcgtg 10621 gtctcacgct cagagcttgc cggagacttg ggtcgggtcg tcaaaagagg gcttcgatgt 10681 cgctgggact ggtgaccagc aggtgttcca gttcttgagg ggtgattttg atgtggccgc 10741 cctccggggt gtcggtgcga gtcaggccag gacgggacaa gcggtggtga tcgccgtact 10801 gatagtagga gaacgggagc cccgccgcgt gcagtgcgcg ggtgagggcc cattcccgtt 10861 cttctgaagc ctgtacgtcg acgcccttgt cccgcagctc ggggatgacc tcccggtatg 10921 acatgtccga cagcgggttg cctctgacgt cgagcaaggt cagtctcgcg cactccaggg 10981 tgggcgaaat gtccgcgacg aggttgcgtt ccacgctcag cacgagcagc gagggtgccg 11041 tgcggaccgc tccgatgtca cggacgtcgc tgtcggagac cgtgaggctc tcgagtgcgg 11101 ggaatccgcc caggtccggg atcttgttgc tgccgtggcc agacaggatc aggattcgca 11161 gggacttaca gcgctcgagc ccggagctgc cacgggcatg gtggaccacc aagtccatga 11221 tgctgtcgag ttcctcatcc cggaacggtg ccgggtgtcc gacttcgagg gtgatcgctt 11281 cggcgatagc cggttccatc ggtcatcctt tgagggcgtc cctggccttc gcgaacgtta 11341 gtcgcaccgc cgcgaatgcc ttcttctgtt tgccggagag ttccaacagg gtgagtttct 11401 tcaaatcgcc aggcttctcc ctgaacagta catcgatcga acgtccgagc gcctcgcttg 11461 gaatggcgcc gacacccccg ctccacatga gctggaatcc ggacggaccc gcctgtgcgt 11521 cgctgcccag catctcgatg agcagggtga cgtacgcccg ggcggtgcct gtcctgttct 11581 gcatgtagag ggcgcggagc cgatcgtgga actccttggt gccgttggtc agggtcggtt 11641 tgcggtcgtc agtgtagaag gtgcccacgt gcgcacccag cgacacgagg ccttcgccgt 11701 ccagaatgcg ccagatgaca acgttcgtcg gcgatcgcag ggcatcctgc aggcgcagcc 11761 agtccaggcc cttctcgacg ttgcctctct tgtgttgcgc gatggcgacc tcgaggacct 11821 gcaggatgta gttggtgggt atccactcgt gcgtacccgg gttgaggtcg cggaagtggc 11881 ccttgatgaa ctcacggctt ggcgtgtcgt tgtcccagag ccagccgaac ctcgtccagt 11941 tgacgtcgcc gacgcgccgc gtgcgcacca tggtctccag aaacccgtcc agcccaccgg 12001 cgagtttgac cgccgccacc aggtccttgt cggcgtccgc atcccggctg gggaatggat 12061 cccaccgccc gtaggtacca agagcggggt cgaagaccat ctcctcgacg tcgttgacgg 12121 tcttctcatc accttcagcg gccttcttcc cggtggtctt gagtttcggc agcgcgccct 12181 cgtcgccgcc gagtttgtcg aggaacgtcg tacgaatggc ggacccggcc ttgaacaggt 12241 aggtgacggc gacttccttg ttgtccgccg ctctcgggtg cttctcgcgg aactgggtca 12301 cgctctgact gccggcatac ttgacggctt cggactcggt cttgtccagc acggaacgct 12361 gccacagttg cttgttcgag ccggacttgg ccttgctgag caatttgtcc caccacgacg 12421 tgtggacctt ctccgcgaag accttcccgg tgttggcgaa gtcgaactcc agtgccgcgt 12481 ccttcgactt gccattcggg ttgatggcca gcctgatgtg gtggaggtcc ccggacttct 12541 tcaggcttat ggaggtcagg cgatgccgac gcttgatgtc gggcagcccg gcccggaccg 12601 acttcacggt ggcgtttccg tcaccgatga gccggttcgc gtcgcggatg gcggcgtcca 12661 gggcgcgccg cttgtcctgg tccgtgcggc ggtcctcgcg tttgcggttc ttccggcggt 12721 ccggcttctt cgccttgcgc ggtcgcttcg gtttcgccgg tctgcgcggc cttctcggtc 12781 tcgtgggctt gcggcggtgt tgcgggcgct tgggcttctt ccgtttgggc ttgagcttgg 12841 ccgccagttt cttgagcagt ccggtgatct tggtgatgac ccagtcgatg gcgcggctca 12901 ccggccggga cagggcctgg aatatctgct tgaccttgcc cgcgatcccc ccgatgccga 12961 ggatcgcggc cagggccccg atgaggaccg ggatcgaccg tgccaacgcg cgttccacca 13021 gggccgggac gccgccggtg ccgccgcggg cgatggcgat cacggcatcc aggaccgtgt 13081 tgacgaactc gatgatctga cggccctggg tgacgatgaa ccggacgatg tcgatgatca 13141 tcttgcaggc gcggatgaac gccgacgccg ggttgaacag cgacacgatc cacgtcacgc 13201 ccgcgatgat gatcgtcggc agcaggtagg acaccagctt gctgatcagg tccttcttca 13261 ggtccccgac ccgcgacttc aggtccgacc acaagcccgc gacgccgcgt ctcttggcct 13321 ccacgacgat cgggatcgcg tccttgcccg tttccgccgc cgccatcgtc ttcgggttga 13381 ccttgcgggc caggcgggcg cggatgttcg gccatgacag cccgagcaga ccggcgatca 13441 tcaccaggat gccgaggacg tcgaagctcg tcggcaggac caggcccgcc gtgacgccgg 13501 agcccagcag ccaggccagc acgccttgtt ggaggtggcg gcctgcgttc ttcatgaaca 13561 gattgagccc gccgccgaca ccggtgatga gccggccgag gaagccgacc gggtccttga 13621 ggatcaggcc gaccgccgac gcggccttgc gcaggacgcc catcagcagg cggccgagtt 13681 ccttgatcgt gttgatgacg ccgccgatgg cgtcggcggc cttggagacc aggcccttgt 13741 tcttctcctt ctccgccgcg atctcggcgt cgaccgactt gaccgcttcg gtgtacttgg 13801 tggccagagt gtcgaccagt tcggtgccct tgtcgttgac cgtgtccgac agctcgtcga 13861 acttgccctg gaagtccgcg gccgcttccc tgccgatggc acggaggtcc ttgggcaggg 13921 tgtcgaccgt gtgctggagg tccttgcggc ccttggcgat acggtccttg gcatggcgta 13981 gctcgccctc gaccgtgtcg gcgacgtcgg agatgacctg gcgcatcgcg gtcaggtagt 14041 tgtcccgagc gcgttcgtag atccggttgg cctcttccgg gaggtcggcg aacaggtcct 14101 tgacccagcg ggccttgccc cgcagcccgg agtagcggcg ggacttgtac tcgtccatgc 14161 cccgggtgtg ctcgtcggtg aaccggtccc tcgcccgctt ctcgccgttg gtgaactggg 14221 tgtcgacctt cttgtccagg ccggacagga tctcctcgac gtcgcccttg gtctcgtcga 14281 acaccttctg gagcagggcg gtgaccttcg tccgcttgtc ctcgtcgcgg cccttcgtgc 14341 cctccttgcc ggtggtgacc tgctggccgg tggcgacccg cgtggcgtgg agggcaccca 14401 tcgcggccgc gccgctcgtg gcggcggtcg ccttgacctt cttcagctcg gcggcctccc 14461 cggcacgcag ctccttcggg gcggccgccg agtgggcctc catcgtcttc ttgtcccgca 14521 ccgccttgtc gaacgcgggc tcgcccgagt tcttcatcga cagctgctgc tcggtgacct 14581 gcgccgatgc catctgctgg ttgacctggt ccggcccggc cgacatgtcc gtggccgact 14641 tcggcaacgc gtccggggcc gcctggttcg ggttcggggc acccggtttc cccggcaccg 14701 agtccgccgc cagcggcacg acctccttgg cgtccggggc cggttccggc gtggcggcgg 14761 tggtgtcggc gatctcctgg cccgcggcgt ccttgccctc accgaccttg ccctggacct 14821 cggtcttgac ctcttccgcc ttgcccgact ccccgaactt gtcggcctcg tccaggttct 14881 tcggggcccg gtccttgatg gccttctcca ccgcggcgat gaacgactgc ttgtcgaact 14941 ccttcggctg agcggcgtcc atgtcctccg cgtgcgccgc cttgccgcgg gcctcctggt 15001 cgtcggccgg cggcaccgcg gctccctgcg cggcaccggc ctccgcggcc ggcggcgggt 15061 ggctcgacgc cacccgctgc ttcttggccg cgacgtcctt cttcaacgcc tggaacttcg 15121 ggtccgcacc cggtgaccgc ggccctgtcg cttcctgttt cttcgctccc ttgccggggc 15181 ggtcctcggt ttccttcctg tccttctggt cctgctggtc cttctggacc gggcgaggtg 15241 cgggcggggc cttcgccttc cggacaggct tcggctccgg cttcttcgcg tccggcttcc 15301 gcgccgactg ctgctgttcc gggagctgtg ccgaggggga ttgctgagct gcgggcagcg 15361 cacccgcctg agccgcgacg gcctggttgc cgatcaggtc ctgcccgccc ggcagcagct 15421 gcccggccca ccaggacggg aacgggcccg gcccggcacc cggtggcgcc ccacccatcg 15481 ccgccgccat cgccgcgttt ccggccacgg cccgcgtccg cgcgacgacc gacgggccag 15541 gttccacggc cgatcccgac gcacgcgcgg tcgggccccg caggtccgac acctccgccc 15601 cgctccgcat gcgtgcatcg cgcaccgggg gcaccgccgg tgtcgtcggg cgcggagtgc 15661 ggacctttat ctgcacaggc atggtggccg caggttcgca ctcgccccgt cgcggcagtg 15721 ccttcgcggc gtcacggggg cgtctccgga gtgcccggcc ttgctacgcg acggcgtcca 15781 gcgccggggc gatgacggcg aaggcccggt cggtcagtgc ggcggggtcc tcgacgccgt 15841 cgctgtcact ccaccgttgc agcacggcgt cgaaggcggt caaggcaatt ccggcggcca 15901 gctgcgggta caggtccgtc gcggggtcca ggtccagccg gtcggcgacc tccgtcgcga 15961 gaccgtcgcg ccactgtgcc tgacgctcca ggaaacgggc gcggagggcg ggcgtgccca 16021 ggatcagctg caccacgcgc agcgcctggt cggcatggcc ggcgcaggcg tcgatggaga 16081 cccagacggt gtgccgcagc gccaccgacg gcgactcctg agcggggcgg ctcgccagct 16141 ccgcgcgcat gccggtgccc atttcggcca agaactggat gaccacgtcc tccttggacg 16201 cgaagtaccg gaagaaggtc cgcttggaca caccggcggc gatcacgatc tcgtcgaccg 16261 tgaccgcgtc gaaccccttc cgggccagca gcttcagcgc ggcctcggtc agctcgtccg 16321 agacgagctg acgcttgcgt tgggccaggc tcacttcagg gcgagtagtc acccctccat 16381 cgtatatgcc gatgccatcg atggcataaa ggatcgacct tgacaccgaa tgccacatgg 16441 ggcagcttgt gccgtatgag caatcagcag cgctggaccg ccgagcggat ccccgaccag 16501 agcaagcgcg tggtcctcgt caccggagcc aacagcggcc tcggcctggc gaccacccgg 16561 gcactcgccc gcaagggcgc gcacgtgata ctcgccgtac gggacgaggc caaggggcgc 16621 cgggcggtcg cggagatcac cgcggagtac ccggccgcgc agctcgaggt gcgccaactc 16681 gacctggccg acctggagtc ggtccgcgcc ttctccgggc agctgcacgc cgaccacgcg 16741 cacctggacg tgctcatcaa caacgccggc ttgatggcgc cgccccggac gctcagcccg 16801 cagggtcacg aagtgcagtt cgcggccaac cacctcggcc acttcgcgct caccggtctg 16861 ctgctcgatc tgctggaggc cggggacaac ccccgtgtcg tcacggtgag ttcgcccaac 16921 caccggcagg gcaccatctt cttcgacgac ctctccggtg agcgcaagta ctcgcccatg 16981 gggtactaca accagtcgaa gctggccaac gccgtcttcg gctgggaact ccacaagcgg 17041 ctcaccgcgg ccggcagccc ggtgcgaagc gtgctcgccc accccggcta cacctcgacc 17101 aacctccaga cgagttcgcc ggtcggcatg gtgaagttcc tgttcggccg cctcctcctc 17161 ccgctcgccc agtccccgga ccagggcgcg ctctcccagc tgtacgcggc gaccgccccg 17221 ggcgtggagg gcgggcagtt catcggccct gacggcatgg ccgagctgcg cggtgcgccg 17281 aagcgggtgg cgctggccga gcgggcctcc gacgccgaga cctgccgccg cctgtgggag 17341 ctgtcggaag agctgtccga cgtgcggttc gcgttctcgg ccgcggcctg agcccggact 17401 cgatactact ggtgcagagg gctttctctg acagatttac ggcattgaac tgatctattt 17461 ctgcgtgtgt gatctgtgtc accaatgggc gtttcttgac cattctcctt gttagggtga 17521 accactcttt ccaatgccgc tgtgaggtgt tgaagtcgtg ggggacttaa tgggggacgc 17581 cgtgggggac atggcagaga tagatgtggc cggtcttccg gcctatccat tcatcggtcc 17641 ggatgacgat ccatttactc ctgtcaaggg atctgacctg gatcgattcg aggggcccat 17701 cggaaaggtc cggcttccgt ttggcggctg ggcctggctc gtcacccggc atgaagacgt 17761 gcggcagctg ctgcggcacc cgggtttcag ttccgatcag tacaagcccg ggtttccggt 17821 gctgaatccg attccgccga agcaggacga cgcctctggt ctgttcatct tcatggacgg 17881 cgacgcgcac agccgcttcc ggcggatgct gaccgccgag tttatgatca agaacatccg 17941 gcggatcgag ccgctgatcg agaaagacgt gatcgaggcg ttggagcgga tgcgctccct 18001 cggggctccc gcggacctga tgaacgagtt cgcgctgccc gtgccgtcga tgacgatctg 18061 tcacctgctc ggcgttccgt acgccgacca tgacttcttc cagcatcaca gccgcgtgat 18121 catggaccgg aagtccggcc cggcggaggt cgaggaggcc ctcggtgccc tgaccgtcct 18181 cctcgggaac ctcgtcaagg ccaagcggac cgaccccggt gaggatctcc tcagccggct 18241 ggtggccgag cgcgtggtgc cgggcgagct ccgggaggac gaactcgtca gcctggccat 18301 gctcctgctc gtcgcgggcc atgagacgac cgcgaacatg atcgggctct ccgccctcgt 18361 gctcctcgag caccccgagc acctggcggc cctgcgcgag gacccgggcc tggcgccggg 18421 catggtcgag gagctgctcc ggtacctcac cgtcgtacgc accggcctgc cccgtctcgc 18481 cctggaggac gccgagatcg gcggtcagaa gatccgcgcg ggcgagggtg tcgtggcgat 18541 gctggcgatg tccaaccggg acagctcggt cttcggcgac ccggacgagt tcgacccgaa 18601 gcggcgcgag gcgcaccggc acatggcgtt cggcttcggc ctgcaccagt gcatcggcca 18661 gccgctggcc cgcgccgagc tgcggatcgc tctcctcgag ctggcccgcc gcttccccgg 18721 gctgcggtcc gagagggccc tggccgacgt cccgcagcgt cccatggcgg tgacgttcgg 18781 cgtggccgag ctgccggtga cgtggtgacc atgcgcatca cggtgaacag ggagctgtgc 18841 gtcggttccg ggaattgcgt ggcgaacgtc ccggaggtat tcgaccagga cgacgaggag 18901 ggcctggtgc ggcttcagat caccgagccg cccgaggaac ttcatgaact ggtcgaggtg 18961 gctgcccaga tgtgtccagt gggtgcgatc gacgtccagt atcgcgtgac cacgcagtaa 19021 cggcgtcatg cacgggggag tgcgccgtca tgctgtccat tcacgcccgg attcgggaat 19081 ggttcatcgg catgtgtttt ttcgctcccg tgtgaattcc acgcaacagg agagtggata 19141 aattaatagg gggcgttcga gttgaacggt gtaaggcagg cgcgagtcat cgtatgcgat 19201 ccacatccct acgcgcgccg tggcattcgt agagcgcttg agcaggatcc cgcactcatg 19261 gtggtcggtg aggccgggga tatcgtcgaa ctcctttcgg cggtgaatcc gtgcgtaccg 19321 gatgtcgtgg tgctggaggg gcagtcacag atcggccatg tgcaggaact caccggcatc 19381 gacgccgcct tggtcgtcgt gggagacgtc gatacgacta cgcgctggat cggcctgacc 19441 caggccaatg tgcatgccct cgtccactgt gacgaccccg aggaggagct ggtggaggcg 19501 gtccgccggg cgagcgacgg caccggctac gtctcgcccg gcctcagcgg ggcgctgctc 19561 aggttcacgc gcgccatgct gccgcggcac ttgtcggccg tgcccacgca cgcgccgctg 19621 acgtcgcgcg agtccgaagt gctccaactg gtacgaaagg gaatggccaa caaggagatc 19681 gcccgccgcc tgggcctgag cgagaagacg gtcaagttcc atgtctccaa cgtgctcgcg 19741 aaggctcatg tggcgtccag ggcccagctg atcgcgtcgg gcgcggccat gtaagagctg 19801 cgcgagcggg ccgcacgagc gggggcgtac gcacggtgaa ccgtgcgtac gcccccgtcg 19861 tcatgtccgc gcacccgagc ctggtcgaaa gtcctggttc cacgggacgg tcctgcaccg 19921 aagcccggct gccgagcccc atcctctggc cgaagtcgtg cccccgttcg aaaaccaata 19981 attcccttat gaatccatcc atgtcaggtg tccaggagac cggcggggcg cgcgacaccg 20041 ccatcgcggt gatcggagct gcctgccggg tgccctcggc gtccagcccg gcagagttct 20101 ggcgcctgct gtcggagggg accgacgccg tctcgccctg gccgacggag cgcggcgagg 20161 gcagccggtc ctggcgtggt ggctttctgg acgaggtcgg caccttcgac gccgccttct 20221 tcggcatgga gccggacgag gcggccgccg tggatccgca gcagcggctc gcgctggagc 20281 tggtctggga ggcgatggag gacgccggtg tccgcggcga gcggctgcgg ggctcacgca 20341 ccggagtgtt cgtaggcgtc tcctccgacg actacgccgc cctcgccgcc cgtggcgacc 20401 gggcagggcg cggcgagctg cacgacttca cggggcggca ccgcgccatc gtcgccaacc 20461 gggtctcctg gtccttcgga ctccaggggc ccagcctcgc cgtcgacgcg gcgcaggcgt 20521 cgtccctggt cgccgtccac ttggcctgcg agagcctccg ccgcggggac tccgacctcg 20581 ccttcgcagg cggggtgaac ctgatcctct cggcggacag catgcggacc acggccggtc 20641 tcggcgcgct gtccgccaag gggcgctgcg ccgccttcga cgagagcgcc gacgggttcg 20701 tacgcggtga gggcggcgga gtggtcctgc tcaagccgct cgcccgggcc gtcgccgacg 20761 gcgaccccat ctactgcgtc atccagggca gcgccgtcaa caacgacggc ggcggcgacc 20821 gcctcaccga ccccgacgtc gcgggccagc gggacgtcct gcaccgggcc tacgccgacg 20881 cccggatcag ccccgagacc gtccagtacg tcgaactcca cggcaccggc accccggtcg 20941 gagaccccgt cgaggccgcc gccgtatccg atgtcatcgg ccggagcagc ggggaccgcg 21001 ggccgctgcg ggtgggctcg gtgaagacga acgtcggcca cctcgaggcc gccgcaggga 21061 tcgtgggcct gctcaaggcc gcgctgtccc tgcgccaccg tcaactgccg cccagcctgc 21121 acttcagcac ccccaacccg gcgatacccc tggccgagct gaacctccgg gtgcagaccg 21181 aactcgacgc ctggcccgcc cccgatgccc cgctcgtagc gggcgtcagc tcgttcggca 21241 tcggcggcac caactgccac gtcgtcctcg ccgaagcgcc gtacaccggc cgccccgaca 21301 ccgcggtgaa ccgcccggag accgcacggc ccgtgccctg ggtgctgtcc gcccgcaccg 21361 gccgcgccct ggacgcgcag gccacccgtc tgctcaccca tctcgagcag cagccggaca 21421 cccacgtcgc cgacatcgcc cggtcgttgg cggtcggccg gtccacgttc gaacaccgcg 21481 cggtcgtcgt cggcacggac agggacgggc tcacatcgag cctggcccgc ctccacgacg 21541 acgcggtgaa cggcatcgcc acgtcgggcc ggacggcctt cctcttctcc ggcggtggct 21601 cccagcgcgt cggcatgggg cgggaactgt acgagacgta cccggtcttc gccgacgccc 21661 tcgacgaggt gctcgaccac ttcgtgcccg gtctcgacct gcgcgaggtg ctgctcggcg 21721 gactcgacga cgatgccgcc gccgacgccc tcgacggcat gcgctacatg cagcccgccc 21781 tgttcgcctt ccaggtcgcc ctctaccgcc tggtcacctc ctggggcgtc acgcccgacc 21841 tgctcgtcgg ccactccttc ggcgagatcg tcgccgccca tgtgtccggg gccctgcccc 21901 tggcccacgc cgccgccctc gtcgccgcgc gcggggagct gatggaggaa ctgccgcccg 21961 gtggcgccat gatcgcggtc gaggcgacgg aagaggaagc gctcgcggcc ctcgacggcg 22021 tcgacgacgt ctcgatcggc gtcatcaacg ggccacgggc cgtcgtgctc tccggcgccg 22081 acgaggcggt cacccggatc gcggacgagt tccgcgcccg cggccaccgc acgagccgac 22141 tgcgggtgca gaacgccgcc cactcgccgc tgacggcccc catgctggac gagttcgccc 22201 gcaggatccg gggcctcgcc gtctccgaac ccggcatccc catcgtctcc accgtcaccg 22261 ggcggaccgg ggccgccctg acggaggact actggatcgg gcacctcggc gccacggtgc 22321 gcttccacga cgcgatcgcc gcctgccgtg agcagggcgt gacccggttc ctcgaactcg 22381 gcccgggcag cgcgctgacc ccgctcgtcc ccacgtccga cacggacctc gcggtggcat 22441 tgcagcaccg cgaccgcccc gagccgcagg cgctgctcac cggcctcgcc gaagcctggt 22501 gcgccggtgt ctccgtcgac tgggccgaga cggtcggcga ggcccgaacc gtcggcctgc 22561 ccacctacgc cttccagcgc cggcgctact ggctcgacga acgcccggcc gccgccgagg 22621 ccgagcagca cgtcagctcc gccaccctcg ccctgcgcga gcgcatcggc accgagccgg 22681 acggattcct gatccgctgg ctggccgacc acatggcgga gaccaccggc gccgcccccg 22741 ccgaccccga cgcgaccttc cgcgacctgg gcctggactc ggtcctctcc gtgcagctgc 22801 gcaatcgcct cgtctcggcg accggcctgc ggatgcccgc gagcatcctc ttcgactacc 22861 cgacgccgag cgccctcgcc gcgcatctgc acgaccagat cctcggcgtc ctgggcaccg 22921 tggacgacac ccggaccacc gcccccgtga cgaccgccac cgacgacgat ccgatcgcca 22981 tcgtcggcat ggcctgccat ctgcccggtg gaatcgactc gccgcaggag ctgtggcagg 23041 cactcgtcac cgaggtggac gccacgtccg agtttcccac cgaccgcggc tgggacctgg 23101 ccggcctcta cgacccggac ccggaccacc ccggcaccac ctactcccgc cggggcggct 23161 tcctggccgg ggccaccgac ttcgacgccg agttcttcgg gatcagcccg cgtgaggccg 23221 cggcgatgga tccgcagcag cggctgctgc tggagaccgc ctgggaggcc ctggagcgga 23281 gtggtgtcga tccggcctcg ctgcgcggca gcaggaccgg cgtgttcgtc ggcgccatga 23341 acatggagta cggaccgcat ctgcacgccc cggtcgacgg caccgagggc ttccgcctca 23401 ccggcaacac ctccagcgtc gcgtcggggc gcatctcgta tcaactgggg ctcgagggcc 23461 cggcgatgac ggtggacacg gcgtgctcgt cgtcgctggt ggcgctgcat ctggcggtgc 23521 agtcgctgcg caacggcgag tgctccatgg cgctcgccgg tggtgtgacg gtgctgtcca 23581 cgccgggcat gttcgtcgaa ttctcccgcc agcgcggcct cgccgccgac ggccgctgca 23641 agccgttctc cgatgacgcc gatggcacgg gctgggccga aggcgtgggc atgctcgtgg 23701 tcgagcggct ctccgaggcc gagaagcacg gtcatcaggt cctggcggtg gtgcgtggtt 23761 ccgcggtgaa ccaggacggt ggcagcaatg gtctgaccgc gccgaatggt ccttcgcagc 23821 agcgtgtgat ccgtgatgcg ctggccggtg cgcggttgac gtcggcggat gtggatgtgg 23881 tggaggcgca cggtacgggc acgtcgttgg gcgacccgat cgaggcgcag gcgctgctgg 23941 caacgtatgg ccaggggcgt gacgccgacc ggccgttgtg gctggggtcg gtgaagtcca 24001 acatcgggca cacgcaggcg gcggcgggcg tggccggtgt catcaagatg gtgcaggcga 24061 tgcgcaacgg ggttctgccg cgctcgctgc acgtctccgt gccgtcgcgc catgtcgact 24121 gggagtccgg tgacgtccgt gtgctgacgt cgcaccagga gtggccggag ctggagcggc 24181 cgcgccgttc ggcggtgtcg tccttcggta tcagcgggac gaacgcgcac gtgatcctgg 24241 aggcggcgcc ggccgaggtg ggggcggccg tccaggaggt tgagccggta cgtgagagca 24301 gcgtgccgtg ggtgttgtcg gcccgcagcg aggcggcgtt ggcggaacag gcggcgcggc 24361 tgctggcgcg ggtcggtgat ggtgctgatc tggatgcgcg ggatgtgggg ttcacgctgg 24421 ccggggggcg tgcggtgctg gagcaccgag cggtcgtcct cggtggggac ggtgctgaac 24481 tgaaggctgg attggcggag ttggccgccg gccgcctggc ctcgaatgtg gtcgagggcc 24541 gggcgggggc cggggcgtcc agtggtgtgg tgttggtgtt cccgggtcag ggttcgcagt 24601 gggtggggat ggcgcgggag ttgttggagt tctcgccggt gtttgcgtcg cggatggcgg 24661 agtgtgcggc ggcgttggag ccgtacgttg atggctggtc gctgttggat gtggtgcggg 24721 gtggggacga ggacgtactg cgccgtgttg atgtggtgca gccggttctg ttcgcggtga 24781 tggtgtcgct tgcggagttg tgggggtcgt tgggtgtgcg gcctgcggcg gtggtggggc 24841 attcgcaagg ggagatcgcg gcggcgtgtg tggccggtgg gctgtcgttg gaggatgcgg 24901 cgcgggtggt ggcgttgcgg agtcgggcga tcctgcggtt gtccgggcgt ggcgggatgg 24961 tgtcggtgct ggcgcctgag gagcaggtgg ccgggcggtt gtccgagggt ttgcagatcg 25021 cggtggtcaa cggtcccgag caggtcgtgg tgtcgggtgc gccggatgag ctggaggtgt 25081 tcctcgccgg gtgtgaggcg gatggggttc aggcgcggcg tatcgcggtg gactatgcct 25141 cgcactcgcc gcaggtggag gatctgaggg aggaacttct cgacgttctg gccggtatcg 25201 agcctcgcag tggccatgta ccgctgttct cgacggtgta tggcgaggtc atcgacacgg 25261 ccgacatgga cgcggagtac tggttcacca acctccgtga gacggtccgt tttgatgccg 25321 ctcttcagaa gctgctggaa gccgggcacc gcgtgttcgt cgagagcagt ccgcaccccg 25381 ttctggtcgg ggcggtgacc caggccgcgg agggcagcgg ggtggccggg gtgacggcgg 25441 tgggcacgtt gcgtcgtcgt gaggatgagc gggcgcggct gttgcagagt gtggccgagg 25501 tgttcgtggc cggtgtggag gtggactggt cgtcgtgggt ggcgggcggt cggctggtgg 25561 agttgccgac gtacgccttc cagcggcgtc gtcactggct tcccgcgggg cgttcggtgg 25621 tggatgcggc aggtcttggt ctgcgtccgg ccggtcaccc gctgctcggc gcggccgttc 25681 ccctcgcgcc ccaggagggc cttgtcctca ccggtcagct gtccctgcac acgcacccgt 25741 ggctggagga ccacgccgtc ttcggcacgg tgctgctccc gggaaccgcc ttcgtggaaa 25801 tggccctccg cgcgggcgac gaggtcggtt gcgcggtggt ggaggagctg acgctggagc 25861 ggccgctggt gttgtcggcg gaggctctgg tggcgatgca ggtgtcggtg ggggctccgg 25921 acgacagggg gcgccggtcg gtctcggtgc actcccgtgt ccagggcgcg gacgctggcg 25981 ccgaagcggg ggtggagtgg gtccggcacg ccgtgggcgt gctggccgcg gccggtcccg 26041 tggcggagga gcgccttgag ggtgtgtggc cgccctccgg ggccgagtcc gtggatgtcg 26101 ccgaggcgta cgagctgctg tccggcgtgg gatacggata cgggcccgtg ttccggggcc 26161 tgcgctcggt gtggcgagcg ggcgacgagc tgttcgccga ggtccaactt ccggccgaac 26221 ccgacgcgtt cggcgttcac ccggcgctgt tggatgccgc gctgcacccg ctgccgtcgg 26281 gtgacatgaa ggtgccgttc tcctggagcg gggtgcgact gcactcggtg ggcgcgtcgg 26341 tcgtacgggt gcgcctgtcg ccgcgtggcg acggggccgt gagcgtggcc gcgttcgacg 26401 gcgccggtct gccggtggtg acggtggacg agctgcgctt gcagtcgatg tcgcaggagc 26461 agctgggctc cgcggtggcc gccgacccgc tgtacgaggt gcggtggacg gatgtgccgg 26521 tgccggacgg ctccggtggg gtgccgccgg aggtcgtggt cgagtatgtc gagcccggtg 26581 gggacgtccg tacgagcgtg gccgaggtgc tggagtccgt ccagcgcttc ctggccgagt 26641 cggcggacgc cgagtcggcg gaccgtgagg acacccgggg cgggatgacg ggtacgcagg 26701 atccggcgac ggccgcggtg tggggtctgt tgcgttcggc gcaggccgag caccccggac 26761 gcatcgtggt cgtcgacacg gccgaagggg cggacccgaa cgaagccgtg gcactggccc 26821 ttgcttctga gccacaagtc gccctgaagg aaggtcggtt cctcgtaccc cgactggtcg 26881 cgcacgcccc tgaggcggcg acggcgccgg actggaagcc ggacggtacg gtcctgatca 26941 ccggtgccgg tggggcgctg ggccagttgg tggcccggca cctggtcgcc gagcacggcg 27001 tacggcaact gctgctggtg agccgtcggg gtggcgaggg ttcggaggag ctggtcgccg 27061 agctgacgga ggccggggcg acggtggcct tcgcggcctg cgacgtggcc gatcgcgagg 27121 cgctgtccgt ggcgttggcg ggcattcccg gtgagcatcc gctgaccgct gtcatccacg 27181 cggcgggtgt gctggatgac ggtgtggtga ccgcgttgac gcgtgagcgg gtcgacacgg 27241 tgatgcggcc gaaggccgac ggtgcccggc tgctggatga gttgacgcgt gatgccgatc 27301 tggctgcctt tgtgttgttc tcgtcggctg ccggtgtgat gggtacggcg gggcagggca 27361 actacgctgc ggccaacgcc ttcctggatg cgctggcgct gtcgcgtcgg gcggaggggc 27421 tggctgccac gtcgatggcc tgggggctgt ggaccagtga cagcgcgatg accgcgcatc 27481 tggacgacgc cgacatcgcc cgcctttcgc gcagtggcct ggggtcgatg tcgacgtccc 27541 agggcctcgc gctcctcgac gcggccctcg cggccgaccg gccgaccatc gtcccggccc 27601 gcctggacct gtccgccctg cggaaccatg cggcgcgggg caccctgccc gccgtcttca 27661 agtccctggt ccgcgccccg gcacgccgtg cggcggcggt cgtcggcacc ggtcagtcgt 27721 cgtcgtggat cgccgacatg gcggcgctgg acgacgggga ccgtgcggcc gcgttgctcg 27781 aactggtcgg cacgcaggtc tccttggtcc tcggccatgg ttcggcgttg tcggtggagg 27841 cggatcgtgc tttccgtgat ctgggcttcg actcgctgac gggtctggag ttgcggcagc 27901 ggttgcaggc cgcgaccggt ctgcggctgc cgtcgacgct ggtcttcgac taccccacgt 27961 cgaacgcgct ggtcggattt ctggaggagc agatccgggg caccgacgcg gccccgaccg 28021 gacctgtggc ggtcgccacg gccaccgacg acgacccggt cgtcatcgtc ggcatggcct 28081 gccgactgcc cggcgggatc gactccccgc aggcgttgtg gcaggcggcc ctggacggcg 28141 tcgacgcgat caccgagttc ccggacgacc gcggctggga catcgcggac ctctacgacc 28201 ccgatcccga ccgggcaggg aagacgtaca cgcgacaggg gggattcctg cacgacgcag 28261 cggtgttcga tcccgggttc ttcgggatca gcccgcgtga ggccgcggcg atggatccgc 28321 agcagcggct gctgctggag accgcctggg aggccctgga gcggagtggc gtcgacccga 28381 cctcgctgcg tggcagcagg accggcgtgt tcaccggact gatgcccatg gagtacggac 28441 cgccgctgca cgagccgatc gagggcatgg acggtttccg catgctcggc aacgcgtcga 28501 gcgtggcgtc gggtcgtatc gcgtatcagc tggggctcga gggtccggcg atgacggtgg 28561 atacggcgtg ctcgtcgtcg ttggtggcgt tgcatctggc ggcgcaggct ctgcgcaatg 28621 gtgagtgctc gttggcgctg gccggtggtg tgacggtgat gtcgacgccg acgacgttcg 28681 tggagttctc gcggcagcgg gcgatgtcgg tggacggccg gtgcaaggcg ttctccgatg 28741 acgcggacgg tgcggggtgg tcggagggtg tcgggctgct cgtggtcgag cggctctcgg 28801 acgcgcggcg caacggccat cagatcctgg cggtcgtacg cggctccgcg gtgaaccagg 28861 acggtggcag caacggtctg accgcgccga acggcccctc gcagcagcgt gtgatccgtg 28921 atgcgctggc cggtgcgcgg ttgacgtcgg cggatgtgga tgtggtggag gcgcacggta 28981 cgggtacgtc gctgggcgac ccgatcgagg cgcaggcgct gctggcgacg tacggccagg 29041 ggcgggatga ggaccggccg ttgtggctgg ggtcggtgaa gtccaacatc gggcacaccc 29101 aggccgccgc gggtgtcgcg ggcgtcatca agatggtgca ggccatgagg tacggcgtca 29161 tgccgcgcac cctgcacgcg gacaccccct cccagcacgt cgactggaca tcgggcccgt 29221 cagcctgctg acgtcacacc agtcgtggcc ggagagcgac cggccacgcc gttcggcggt 29281 gtcgtccttc ggcatcagcg ggaagaacgc gcacgtgatc ctggaagcgg cgcccgagga 29341 caccacggcc ccggaccccg gcccggcgcc ggaagcgccg atgatcccgt gggcactgtc 29401 ggcgaagacc tccgccgggg tacggcggca ggccgcacgg ctgctcgcgc ggatcaccga 29461 cgaccccggc ctcgaccccc gggacgtcgg atacaccctg gccacggggc gggccctgat 29521 ggagcaccgg gccgtcgtcc tgggggccgg gctcgacgag ctgaccggat cgctgacggc 29581 cctcgcccgg ggcgaggacg tgcccgccgc cgtggccggt gccgtccccg ccgccggagc 29641 gggcgggctc gcgctggtct tctccggcca gggctcgcag cggcccggca ccggccggga 29701 gctgtacgag cggtacccgg tcttcgccga ggcgttcgac gccgtgtgcg cggccgtgga 29761 cgagcagctc gacgggtacg ccgaacaccc gctgcgcgac gtggcgttcg cccccgaggg 29821 ctccccgctg gccccgctcc tccagcagag catgtacacc cagaccggcc tgttcgcgct 29881 ggaggtcgcg ctcctcgaac tgctcaaggc gtggggggtg cgccccgacc acgtcatggg 29941 ccactccctg ggtgaggtca ccgcggtgta cgcggcggac gcgctctcgc tggccgacgc 30001 gtgcaccctc gtggcggcgc gcggtcgcct catgcaggcc ctgccggagg gcggggcgat 30061 ggtggccatc gccgtcgccg agcaggaggc cgaggcgtac atcgcggagg cgtccctcca 30121 ggacgccgtc gggatcgccg cggtcaacgg gccgcgggcc gtggtcgtct cgggtgacga 30181 ggccgccgtg gtcgacgtcg ccgagcattt ccgggccgcg gggcaccggg tgcgccgcct 30241 ctccgtctcg cacgcgttcc actcgcaccg catggacgcg atgctcgacg agttcgccga 30301 cgtggtcgcg ggactcacct tccgggcacc gcggatcccc gtggtgtcga acgtcaccgg 30361 cggtccgatc gacactgagc gcctgtgcac cccccagcac tgggtggagc acgtccgccg 30421 gggcgtccgc ttcgccgacg gcgtgcggag cctggccgac cagggggtca ccgcctacct 30481 ggaagtcggc cccgaggccg tggtgacccc gatggtgcac gccaccctcg acgcggtcct 30541 cggcgacgac ggatacgtgg ccgtggcggc gctcaagtcc ggtcaggggg aagccctcgc 30601 gctcacccgg gcgctcgccc ggacgttcgt cgccggtaca ccggtggcgt gggagctgct 30661 gctgcccggc ggacgccgca ccgaactgcc gggctacccg ttcgcgggac accgctactg 30721 gcaggacgcg tccgagtcga cggtcggcat ccgggccgcc ggtctgaacg ccacccggca 30781 cccgctgctc ggcgcggccg tgcacctggc cgacggccag gcggtgctca ccggccgggt 30841 actgcccggc gcgcatccct ggctcgccga ccacgccgtg ggtggcaccg tactgctgcc 30901 cggcaccgcc ttcctcgacc tggccctcca cgcgggccac gaggtgggct gccccctcgt 30961 cgaggaactg acgctccgga cgcccctggt cctgtcggcc ggcaccgccg tgaacctcca 31021 ggtcgccctc ggcgccccgg acgagacggg ccgccggtcc gtcaccgtct actcctcgcc 31081 cgccgcggtc tccggcaccg agccgctggg tccggcacgc gaccggcacg ctgtccgcgg 31141 cacccccgcc cgccgccgaa gcgtggacct gggccgcctg ccgacgccga nnnnnnnnnn 31201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 31981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 32701 nnnnnnnnnn nnnnnnnncc tgttcgacac cggcgcgctg cgcgccctgc cggtcacggc 32761 gtacgacata cgggcggcgg caacggccta ccgccgcctg gacgaggagg cacacaccgg 32821 aggggccgtc ctgacgatcc cgcgcccgct cgatccggac ggcacggtcc tcgtcaccgg 32881 cgcgagcggc accctgggac agctcgtcct gcggcggctc gtctccgaac acggcgtccg 32941 caacgtattg ctgctcagtc gcagcggcgg cgaggcgccc gaggacctgg tggagcgcgg 33001 cgtacgggtg cagtccgtcg cctgcgacgc cgcggaccgc gagcagctcg cgagggccct 33061 cgcccgtatc cccgcggagc atccgctgac cgccgtggtg cacacggccg gtgtcctcga 33121 cgacggtgtc ctcgaggccc tgacacccga gcggctcgcc accgtgctgc ggccgaaggc 33181 ggacgcggtg ggtgcgctgc acgagctgac cgccgacgcg gacctggcgg ccttcgtggt 33241 gttctcctcg gtcgccggtg tgctcggctc cccggggcag gcgaactacg cnnnnnnnnn 33301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 33361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 33421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn cggggctgct gcccacctcc 33481 acggaggagg gcctcgccgc cttcgaccgg gccctggtgg gcgccctgcc caccgtcgtc 33541 ccggtacgtg tcgacacggc cgcgctgcgc gccgcggaca ccgttccgcc actcctgcgg 33601 gaactggcgc ccgccccgaa ccggcgggcc gcggcgagcg ccccggcggc accggccgag 33661 tccctggaga gcaggctgcg cggccttccg gccgaacagc gcagcaccct cctgctcgac 33721 ctggtcctga aggacgtcgc cctggtactc gggcacggcg acccgcgcgg catctccgcc 33781 gacggggcgt tccgcgacct gggcttcgac tcgctgacgg ccgtcgaact ccgcaacaag 33841 atcaaccatc gcaccggcct gaagctgagc gcgaccgcgg tcttcgacca tccgagcccg 33901 cgcgccctgg tcgaccacct gctcgaccgg ctcaccgcgg cacccgaaac ggcgcgagac 33961 gccgaagagc cgagctacga acgggtcgtc gccgacctca ccagggtcgg gaacagcctg 34021 gccgcgctgg agctcaccgc cacccaacga gccgccctcg ccgaggtctt ccgtggcctg 34081 gccgagccct ggacgggcgg agagcccgtg gcggcggccg acgaaccggc gtcggccgac 34141 ctcgaatccg cgaccgcggc ggaagtcctc gacttcgtca ccaacagcct cggcatctcc 34201 atctccggcg acatctccgg cgacggatcg cccaccgacc cgagttgaga gtgagttcat 34261 gcccaccgaa gacgagctgc tgaaatacct caaggcggtt tccgaggaac tgcacgtcgc 34321 tcgcgggcgg ttgcagacac tcgaaggccg ccgcagcgaa cctgtggcga tcgtcggcat 34381 gagctgccgg ctgcccggag gcgtgtcctc gccggaccac ctgtgggacg tcgtcgccaa 34441 gggagaggac gcgatcggcg cgttcccggc ggaccgcggt tgggatgtcg acgcgctgta 34501 cgaccccgaa ccggggaccc ccggcaagac ctacacccgc tccggtgggt tcctgcacga 34561 cgcggcggac ttcgatccgg cgttcttcgg gatcaccccg cgcgaggcgc acgggatgga 34621 cccgcagcag cgcctgatgc tcgaggcgtc gtggcaggcc ctggagagcg cgggcatcaa 34681 cccgcagacc ctcaagggca cccgcaccgg tgtcttcgcc gggtccttcc accacgacta 34741 cgacccgggc ggcggcagcg tcggcagcct cgtctcggga cgcgtcgcgt acgcactggg 34801 cctccagggg cccgccgtca cggtcgacac ggcctgttcg tcgtcgctgg tcgcgctgca 34861 ccaggcggtg cagtcgctgc gcgagggcga gtgcgcgttg gccctggccg gtggtgtgac 34921 ggtgctgtcc accccgggtg tcttcatcga gttctcccga cagcgcggcc tcgccgccga 34981 cggccgctgc aagtcgtacg ccacggccgc ggacggcacc ggctggggcg agggcgtggc 35041 cgtgctcgcc ctggaacgcc tctccgacgc cgagcgccac ggccaccggg tcctggcgct 35101 cgtccgcggt acggcggtca accaggacgg cgcgtccaac ggccagacag cacccaacgg 35161 cccgcacagc agcgggtgat ccaggacgcc ctggccagcg cgcggctgac ctccgccgac 35221 gtcgacgtcg tcgaaggaca cggcacaggc acgaccctcg gcgacccgat cgaggcgcag 35281 gcgctgctgg cgacgtacgg ccaggggcgg gatgaggacc ggccgttgtg gctggggtcg 35341 gtgaagtcca acatcgggca cacgcaggcg gcggcgggcg tggccggtgt catcaagatg 35401 gtgcaggcga tgcggtacgg cgtcatgccg cgcaccctgc acgtggacga gccctcgcac 35461 cacgtcgact ggagcgaggg tcaggtcagg ctcctgacgg aggacagggc gtggccggag 35521 ctggagcgtc cccgccgggc cggtgtgtcg tccttcggct acagcgggac gaacgcgcat 35581 gtgattttgg agggggcggc gccggttcag gaggccgggc cggttcgtgg cggggtcttg 35641 ccgtgggtgt tgtcggcgcg cagtgaggcg gcgttggcgg agcaggcggc gcggctgctg 35701 gccagggtcg gtgacggtgc tgatctcgat ccgcgggatg tgggcttcac gctggccggg 35761 gggcgtgcgg tgctggagca ccgggcggtc gtcctcgggg agagtgacag tgaactcgcc 35821 gccggattgg gtgagttggc tgcggggcgt ccggtggcgg gtgttgtcgc ggggcgtgcg 35881 gtgtcttccg gtggtgtggt gttggtgttc ccgggtcagg gttcgcagtg ggtggggatg 35941 gcgcgggagc tgttggagtt ctccccggtg ttcgcgtcgc ggatggcgga gtgtgcggcg 36001 gcgctggggc cgtacgttga tggctggtcg ctgctggatg tggtgcgggg tggggacgag 36061 gacgtactgc gccgtgtcga tgtggtgcag ccggttctgt tcgcggtgat ggtgtcgctt 36121 gcggagctgt gggggtcgtt gggtgtgcgg cctgcggcgg tggtggggca ttcgcagggt 36181 gagatcgcgg cggcgtgtgt ggccggtggt ttgtcgttgg aggatgcggc gcgggtggtg 36241 gcgttgcgga gtcgggcgat cctgcggttg tccgggcgtg gcgggatggt gtcggtgctg 36301 gcgcctgagg atcaggtggc cgggcggttg tccgagggtt tgcagatcgc ggtggtcaac 36361 ggacccgagc aggtcgtggt gtcgggtgcg ccggacgagc tggaggtgtt cctcgccggg 36421 tgtgaggcgg atggggttca ggcgcggcgt atcgcggtgg actatgcctc gcactcgccg 36481 caggtggagg acctgaaggc cgaactcatc gatgtcctcg gggagattga gccgcgtacg 36541 ggtcacatac cgctgttctc gacggtgtat ggcgaggtca tcgacacggc cgacatggac 36601 gcggagtact ggttcaccaa cctccgcgag acggtccgtt tcgacgccgc tcttcagaag 36661 ctgctggagg ccgggcaccg cgtcttcgtc gagagcagcc cgcaccccgt cctgctcggc 36721 gccgtgacgc agaacgccga tcaccttcgt acgaccggag tcagcgccat cggcacgctc 36781 cgccgcaacg agggcgagga ggcccaactg ctgcggagcc tggccgaggt gttcgtcgcg 36841 ggcgtcgatg tggactggtc gccgtgggtg gcgggcgggc ggctggtgga gttgccgacg 36901 tacgccttcc agcggcgccg gtactggcag cccgccgcct cggccgccga cgtcggctcc 36961 gcgggtctgg acgcggtgcg gcatccgctg ctcggtgcgg ccgtacgcct cgcgggcagc 37021 gacgacgtcg tgctcaccgg acgcatatcc cgcgccacgc acccgtggct ggaggaccac 37081 gccgtcttcg gcacggtgct gctcccggga accgccttcg tggaaatggc cctccgtgcg 37141 gccgacgagg tcggctgcga cgcgctgcgg gacctgaccc tgcacgcacc gctggcgctt 37201 cccgaacagg gcgagatcga catacaggtg cagatcgggg ccggaaccgg taccggccgt 37261 ccgctggaca tctactcccg gccccgtcgg cacgacggca cggccgagtg gacccagcac 37321 gcgagcgccg tactcgccac ggacgccgtc cccgccgaca tcaacgggcc gctgttcggc 37381 gccgcgtggc cgcccgccgg tgcggagcgc ctggacgccg ccgaccacta cgacacgatg 37441 gccgccgcag gtctggagta cggaccggcg ttccagggcc tctccgatgt gtggcggctc 37501 ggcgacgaga tcctcgccca ggtcaccctg cccgggcggc aggcggagga ggcgcagcgg 37561 ttcgccctgc accccgccct cctcgacgcg gcgctccagg ccgcggcggt ggacggtctg 37621 gacggccgta cgccgctgcc gttctccttc ggaacggtcg ccctgcacgg ccgcggtgcg 37681 agcgaggtgc gtgtgcgcat cgcccccacc ggggcggaca ccttcacggt ggaggcggcc 37741 gatccgtccg gcacgccggt cgcccggatc gactcgctcc tcgtacgccc ggtgacggcg 37801 ggcgacctgg ccacggcgga cggcagcacg acggcgctgc tgtccgtcga gtggtcgccg 37861 tacgcggcgg acgcggacgc ctcggccgtg gacccgggcg cggacgcacc ggacgtgacg 37921 ctcttgaagg ctgccgatgc cggacccgcc gccggtgacg aggccgcccg ggcgcgggcg 37981 gtgctgcggg acaccctgcg cggtgtgcag gagtggctgg cccaggaccg gcccgcctcc 38041 gcgcgcctgg tcgtgctgac ccgccgagcc gtgctcaccg gcgccgagga gcccgacgcc 38101 gccgtcgacc tcgcccatgc ggccgtgtgg gggctggcca gggccgcccg tgcggagaac 38161 cccggccgcg tcgtcctcct ggacgtcgac ggcgagctgg acggtctcga cgaggccgcg 38221 gtccacgatg cgctgcgtac cggacgccat gaactggcct tgagggaagg gaagttgtac 38281 gttcccgccc tgcgccgcca ggagacggca ccggtggccg acggcgtggc cgaggcactc 38341 ggcacgggca ccgtcctgat caccggcggg acgagcggcc tcggcgcaca ggtggcccgg 38401 cacgccgccc ggcacggggc ccggcatctg ctcctgctgt cccggcgcgg ctccgcggcc 38461 gagggggccg aggcgctgcg cgacgaactc gccgcctccg gggcccgggt caccgtgcgg 38521 gcctgcgacg tggccgaccg cgaccagttg gagcgcgcgc tgcgcgatgt gcccgacgcg 38581 tatccgctga ccgccgtcgt ccatgccgcg ggcgtgctcc acgacgccgt cgtcgagtcg 38641 atcgacgcgt acggcctgga cgccgtgctg cgcccgaaga ccgacgccgc ctggcatctg 38701 cacgaactga ccgccggnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 38761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnacg 38821 cgttcctcga cgcgctggcg cagcagcgcc gccgcaccgg tcggcccgga ctgtccctgg 38881 cctggggcct gtgggcggag gccaccggca tgaccgggca cctcggcgcc gcggacctgg 38941 agcggatcaa gcgcggcggg gtcgccgccc tggacaccga ccaggggctc gggctcctgg 39001 acgccgcgct cgcccgggac acggacgatg cgctgctcct cgccgccgcc ctcgacgagc 39061 ccgtcctgcg cgccaccgcg cctggcctgc tgcccccgct cctcgccggt ctgttcccgc 39121 cgcgccgccg cgtcgccgtg gcccgcgccg ggcgggcggc gggcgcggac ggccgcatgg 39181 cgctcgactc gcgggacgcg gtcgtggacc ggctgcggta ccggttcgcc ggaaccatgg 39241 ggttcgacac cacggagatc gaccccgccg cgccgctcgt cggccagggc ctcgactccg 39301 tgatggccat gcagatgcgc agcctgatcg agtcggactt cggccaggcc ctgcccgttg 39361 gctcgctgtt caacggcgcc agcgtcgaga gcatcgccga ccagctcatc gcgggcgcgg 39421 gccggaccgt cgacggccct gacgcgagcg ggggcaccga ggacgccgag gacatcccgg 39481 acgtcgtacg ccaccccgcc acccgggacg tcgtacgcct gctccgcgcc gagcagcacg 39541 gcacgcccgg cgtcacccac cacatcggcc tcgccgtgcg gctcacggcc ccgacgacgc 39601 cggaccgcct ggccgaggtg atcgcctcgc tgaccgcccg gcacgccgcg ctgcgcaccg 39661 cgatcgtccc ggacgccgac ggcgggctgc ggctggaggt ccggcgttcc ctcgacgacg 39721 acctggtgcg ctggtcaccg gtggacgagg gcacggacgt ggacgagcgg ctgcgcgcgc 39781 tgatggagcc gccgttcgac ctgtccctcg ccccgctgtg gcggttcgag ctgctcgcgt 39841 acccgtccgg tgagcaggtt ctcgtgttcg gcgcgcacca cgcggtctcc gatctggcct 39901 cgctgatgct ggtggcccac ggcctcggcg ccggactcgg tggcgccgag ccgcccgcag 39961 ccgtcaccaa ccgcgacatc gacctgctgc tgcgggcaca ggccgagcgc ccggcggacg 40021 agcagggccc gtcggccgcc tggcgcgagg acttcgtggg ggcccggcgc ctcgacctgg 40081 aactggccgg gccgcggccg gtggagcggt cgttccgctc ggccatgcac ctggccgacc 40141 tgccgcagga cctccacgag aaggtggcgg cccgggcgaa ccgcctcggc atcacgcccg 40201 ccgccttctg gctcggtgtc ctgacggtgc acctcgcccg gctgcgcgag cggaacaggt 40261 tcgtcctcgc ggtccccgtg gacacccgcc tgcacgtgtc cgccccggac gcggtcgggt 40321 acttcggcct gcccatcccg tacgccgccc aggtggaggc gggggaggcg gcagtcgacg 40381 tactgcggcg caccgacagc cggctgagcc gggtcctgga acgcggcgtc acgttcttcg 40441 acgcgatgtc cgccctcgtc gaggaggggc tgtaccgcaa ggacgcgccg ctcgtcgagg 40501 tctacttcaa ctacatgccg ccgcacgccg gtgccgcgga gggcctgcgg atcgtcccgg 40561 cgggcaccgg ctactccgac ctcgacctga tggtcaccgt gatgccgggg ctcgggaagg 40621 tcggcctcga atacaacgcc gacgtcctcg acgaggcgaa ctgcgcggac ctcgcgcgcg 40681 gctgcctcgc cctcgccgcc gagatcgccg acggccccga caccctcctc gcgctaccgg 40741 aaggacccac caccgtggcc cccgagcccg cgacggccat cgagcccgcc gtggcccccg 40801 aacccgcgca gcggatagcc gtcgcggcca ccttcgccct cggcaatctc ccggccatgc 40861 tgtcggtcgc cctggaggac gccggtgtcg acggcgggcc cttcgacgtg gccgaggccc 40921 cctaccacca ggtcctggcg agcctgcacg acccgggcag cgtcctcgcc cggacgccga 40981 cggtcgcgag cctcgtcctg ctgcgtcccg gcgacctgac gcgcttcgcg gacaccggcg 41041 acggcggcga cctgctcgcc cagctcgccg acgagtaccc gaccgccctg cgcgccctcg 41101 ccgaccgcac ccgcaccccg ctcgtcgtgg ccttcctgcc ggagcgctcc gacgatgaac 41161 ggctgcgcgc gtgggagcga caggtcacgg cgcgcctcgc cgaccggccg ggcatcgccg 41221 tactgccctc ggacacgtgg aacgacgacg actacccggt ggccgacgtg ttcgacgcgc 41281 acaccgacac catggcccac ctgccgttcc aggacgagtt ccaggcggtc gtggcgctgc 41341 ggctcgccga tgtcgtctgg aaggtccgcc gccgggcgcc caaggtgatc gtcgtcgacg 41401 gcgacgagac gctgtggagc ggtgtggccg gtgagatcgg ccccggcaac gtcgacctga 41461 ccggtccgcg cgccctgctc gcgcagcggc tgctccagtg gcgggaggcc ggagtgctgc 41521 tcgccctggt ctccaacaac gacgaggaca cggtgcaccg gatcctcgac cgtccggaca 41581 gcccgctgca ccgggagcac ttcgccgcga tctccgcggc gtgggagccg aagtggacgc 41641 ggatcgtgaa gatcgccgag gagctgcggc tcggcctcga cagcttcctg ttcctcgacg 41701 acaacccggt ggagatcgcc ggggtgcgcg cccagttgcc cgaggtgctg tgcgtcacct 41761 gcccgggcgc cggcgaactc gccgacttcg tcgcccggct gtggccgatg gtgccgcggg 41821 ccgcgacggc ggaggactcc gccagggccg agttctaccg gcaggagcag gtgcgcggcg 41881 aggcccgggc gcacctgggc ttcgccgagt tcctggagaa cctccagctc gaactcgaca 41941 tcgagcccgt gtccgaggag acggccgagc gcaccgtcca actgagcagg cgcaccaacc 42001 agttcaacct gcggccccgc cctctggacg ccgccggact ggagcggctg cgggaggacg 42061 gcgaggtgtg gacggcgacc gcacgcgacc ggttcggcgc gtacgggcag atcggcgtcc 42121 tggccgtcac cgcggacaac gacgcactcg aagtggtcgc ctggatgatg agctgccgcg 42181 tgctcggccg gggcgtggag gaccggctgc tccagtggct ggccgaccgg gccgaggccc 42241 acggatgcgg cacggtgcgt ctcgtcgccg accacacgcc ccgcaacatt cctgcccggc 42301 gcctggtctc ccgcctgggc ggcggcgacg tcgaggcacc gcgcctggag gtggcggtgc 42361 cggtggcaca actccgggag ttccgttcct gggacctcgg atccgaaaac gcagcggagg 42421 tcagcaatgc ctgaggcggg cagcggcacc agccgcaacc gcagtgtcaa ccgccgtccc 42481 gaggaggagg tgatcgagcg gcgcggcccc ggccgcgccc aggccaccga cctcctggcg 42541 cgcttccgga agacggccga acgcgccgcc ccggaaccgg cacccgccga cggggcgggg 42601 gcccgcggtg tcatggaggt cgccgcggac atcgtcgccc gggccgcccg cttcctgccg 42661 gggaacacgc ccgacgccga gacggacctg ttcgacgccg gtctgtcgtc ggtcgacgcg 42721 gtcgagctcg tcgcggtcat ggcccgggaa ctggacgtac gggtgagcct ggacgacgtc 42781 ttcgcggacg cgcggccccg acgcctcgcc cagcgctggg ccgccgctgc ggggctgccc 42841 accgcggtgc ccgacgcccg gccggacgcc ccgtcaccga gcacgccgac cacgtcgtcg 42901 tcgaacggtt cgccgtcgat cgcgccggtc gtcgtccgcg cgtcggacgg cggggcggac 42961 gaggacctgg agatgatcct ggccgacctc gcgctcgccg accggctgcc gttcagccac 43021 caggccgacc gggttccgcc gcgccgcatc ctgctcaccg gcgccaccgg ctacctcggc 43081 agccacctcc tgctcgacct gctgcggcag cgcgacgccc atgtggtgtg cctggtgcgc 43141 gcggcggatg acgccgccgc cgaacgccgc ctggccgacg ccctggcgag cttcgaccag 43201 ccctggtcca gcgaggtccg gcggcgggtc acggtgctcg cggcggacct caggcagccg 43261 cgcctcggcc tgtcgccgga gggctgggag agcctggccc aggagatcga cgcgatcgtc 43321 aacgtcgccg ccgcggtcga cttcctgcgc ggctacccgt cgctgcgcca gaccaatgtg 43381 ctcggcccgc tggtcctcgc cgagctggcg atgaccgggc ggcccaaacc gctgcaccac 43441 atctcgtcgg tcgccgtgtt caacgaggtc ggcatcgaga agatgggcga ggacgacccg 43501 gtcgcccaca tcgaccggct cgtcgcgggc tacgacaagt cgaagtgggc cgccgaggcc 43561 gtgctgcggc gggcccgcga gcacggcctg accgtgacgt tcctgcgccc gggcgcgatc 43621 ggcggccaca cccggaccgg tgtgtacaac ccgcgcgacc tcagtaccgg tctgatcggg 43681 gcgttctccc ggtaccggac cgtcccggcg ttcaagttca tgaacctggc gccggtggac 43741 tggatcagca aggtggtggc cgcggtggtc ttcgatcccc aggcatgggg ccagaactac 43801 aacgtgaccg gccgtgccga gacgctgccg gaactggtca aggacatgaa gctggccggt 43861 atgaacgtac gggtggccaa ctggcgggac tggcgcgacg acctgcttca gcggcatgcg 43921 gccgagccgg tgcccgaact cgacttcctg gtccggatct tgcgcagccc caccgcgatg 43981 aagctgttcg aggcgctgat gttcggcccc gaggccggat cggaacgcac cgagacgttc 44041 gtgacgcggc accgcctgcc gatggccgaa cggtacggcg gccaggcaca gttgaaggca 44101 ttcgagcgga tggcgaagga cggcgtggcg cggctgccca gccgcgagga cccgccctac 44161 ctgtcgttcc gcgagcgtac gaagggccat gtgggcccga tcggggagga tcgcgacacc 44221 aggtgccgga tggccctcac cctgtccatc gcgagcatgt accaggtcgt acggcaccgg 44281 aagatcgacg tccgaggcga ggtgacctgc gagcggctgc acccggagcc gctgacggtg 44341 gaggcgggcg agatctgggt ccgtcccgac gagggcgttc cgctccggca cggcagtgac 44401 caccccctgc tgcgctaccg cctggtgctg gtggaccggg acggcggccg ctggtggctg 44461 gagggctgga agacggcccg cgccagccgt gacttctgga agcagacccg gaccatcgag 44521 gtcaccatcg ggcgcgaggg cgagccggcc ggcctgtccg gtgtggtcaa ggtgccaggc 44581 aagagctacg tcccggacca gatcgacggg atcagggtcg atccgcggct gtcgtcgcag 44641 gagcagcggc tcgccaaact ggcctggctg tcgtggttct tcgtccaggt gggcatgggg 44701 ctcgccgagc cttccctgcg cgtcgccgcc gaactcctgg acctgcgccg ggacgcgatc 44761 gaccgggaca aggacaagct gcaacgcaag atcaggaagc tgatgatcaa aagggagcag 44821 acccgatgac gctgaggccc ctccaccacg cgctcgggga ccgggtcgag gagatcccct 44881 tcacggcctc cgacggcacg gagctcggcc tgtgccgggt cgcccccgag gacggtgcca 44941 ccgaccgccc ggccgtgctg atcctgcacg gtctcaccgc ctcggcggac atgttcacgc 45001 tgcccgagac ccgcaacctg gtcgacgtcc tgctcgacgc gggctacgag ccctggctgc 45061 tcgactggcg cggcagctgc cgtcttccgt acaacgaggg ccgggtgcgc tacaccttcg 45121 acgatgtggc gctctacgac atccccgagg cggtgtcgct gatcagggaa cggatcgacg 45181 gccgcgagct gctggtcgtc gcgcactgca tcggggcgat gtgcctgtcg ctgagcatgg 45241 cggcggggct ggtgcccggc ctggccggcg tcgtcgcgca gggggtgttc ctcacgccga 45301 agatgtcctg gaagacgcgg gcgcgcctgc acttcggcgg ggagctgctc cggtcccggc 45361 tggtcaacat ccccaccgac ttcaagaagg tgggcctgtg gtcgaagcac tcgctgatct 45421 tcgcggaggt ctcgctgggc gccgagtgca aggaccccaa ctgccagatc ctcaacaacg 45481 actcgtgggg cgtgggtggt tcgctcttcg agcacgacaa cctcgatgac gtaacccacg 45541 accgcctggc cgatctgtac ggtacggtgc cgatgtggat attgccgcat ctgcgcagca 45601 tcgagctggc ccacacgatg atgcggtaca acgacgccga cggccgttac gacgcgctgc 45661 cgaagaacgc gctcgacaac gcggggaagt tcgacatccc gctgatgctt ctgtccggca 45721 gcgacaaccg cttctggtac gactccaacg agctctgcca cgacgtcctg acccgccggt 45781 accccgagat ggacgtccgc tatgtggagg ttccgggata cggccacctc gacacgttca 45841 tcggccgcaa cgcggcgctg gacgtgttcg gccacatcgt ggacttcctc gacgagtgcc 45901 gatcggtcaa cgccactgcg gtgcgggagt aggtagacgc atacgatgac gtccgaaatc 45961 gagcagtcgg gtgccgcgcc gtccggtgcg cgcctggtga tgcccatcat cttgctcacc 46021 atcttcacgg tccccttgtc gatatccggg acagccgtgt ccctgggcga catcgcagac 46081 gacctggggt cctcgtcgac cggcgagcag tgggctctca acggatacac actcaccttc 46141 gcctgctcga ccctcatctg gggctccatc gcggacatca tcgggcgatg gcgagccctg 46201 atgtccgggt tggtgatctt cggtgtcggc tccgcgatga gcctggtcgc cgcgaactac 46261 ctggtgctgg acgtggcccg gctggtcgcg ggggccggcg cgggtgccgt cttctcggtg 46321 ggtacggcgg tggtgtcatc gaatttcgag ggtgagcgcc gaacccgtgc cttcgccctc 46381 ctgggatcgg tcgcgggtct gtccctggcc ttcggcccgt ccctgtgcgg tctgttcacc 46441 caggtcgtcg gctggcggtt cgtctacgga ttccagctgg gctgcctggt catcgcgtgc 46501 ctcggcatgc cgttgatccg ccgggcggcc gcccacgaga agcggtacgc ggcccggatc 46561 gacgtggccg gagcggtgct cttctgcgtg gcgaccacgc tgacgctcgg tggtttggca 46621 ctcggttcgg cgacggggtg gctgtcgctc cccttcctgc tgtgcacggc cgccgggttc 46681 gtcgcttacg gactgttcgc atggcgggaa tccaccgcgc cgagccccct gctgagcctg 46741 cgcactctgc ggaacaagcg cttctccgga atgacgttgg tggtggcggt gtcatccttc 46801 accttcacca acgcggtggc ctacctgccg gtcttcttcc agggcgccta tggctcctca 46861 ccgggcgcga gcggcgcgtt cttgatgttc ctgaccatgc cggtgctgat ctccccgctg 46921 atcgccggac gtctggctgc ccgggggacg gccgtggaca cgatcctgat ctggagcatc 46981 gcgctgatgg tcgtgggtct ggtggccacg ggcgcggtcg cggagcaggg cctcgcatgg 47041 atgacgttcc cgatggtggt cgtcggcgcc ggattcgggc tccaggccgg tctgatcgac 47101 ggcgaggcat tggcgcaggt gcccgcgaag gaggcgggca tggcggccgg atggatcaat 47161 accgtccggc tgggaagcga ggccatcgcg gtgtcgctgt tcggctcgct gttcgccagt 47221 ttcgcgggca acgccgacca cgcctcccgt cagggcttcg cgggcatcac gatcggctcc 47281 accttgttcg cggcggtgat cggtctgctg tcgatactcc tgctgcgccg aggccggcag 47341 agcgaaacgc caccgcggga gcagcgtctc atcgcccggg gctcggggcc tgcgccgcgg 47401 cgcggtgctc ggtcggagtg atgccgcgga gccgtttgaa ggcgacgctc agcgcgaagg 47461 tgttggcgta gccgaccttg cgggcgatcg agccgaccgt ggcgtccgtc tcgcgcagca 47521 ggtcggccgc cacgtcgacg cgccaggagg cgaggtaggt catcggtggt tcgccgacct 47581 gtgcggtgaa gcggcgggcg agcgcggcgc gggacactcc cgacgtggcc gccaggctcg 47641 ccacggtcca tgggtgggcc ggatcgtcgt ggagcagttg cagggcgtgg ctcaccgccg 47701 ggtcgtccat cgcgcggtac cacggcggtg cgtgggcctc cgactggtcg aaccaggtcc 47761 gcaacgtgga gaggagcatc aggtccagca gccggtcgcg catggcctgc tgcccgggtc 47821 tgtccctggc gatctcctcg atgaccagat cccgcagggg gcggtggcag tcggcgtcgg 47881 gaagcaccgt gacgtcgggc agggcgtgca gcagccgttc gctgatctcg ccccggccgg 47941 tgtaggcgcc gctgagcagg agggccgagc cgtcggggtc ctcggcggtc tcgttcttgt 48001 cggcgtcgcg tacacagtaa tcagcgctgg tgatcacggt ctgcggtggc gtggccgggt 48061 cgtccgcaac cgtgtacggc gcccggccgc ggaggatcgc gatgtctccg gggccgaccg 48121 gcaccggttc gccgttctcg gggacgatcc acgcccggcc gcgcagcatc gtggccagcg 48181 tcagaggtga gccgctggcg aaccgcaggg accacggccg gttcatgacg gtccgttgga 48241 acaaggcacc gcgtgcccgc accccgtcca gcagttcgga gagcacatcc atgcccctac 48301 cgtagacgcg cggacatcga agtgagtctc tgagccatgg accgtctcac gcgaagtggc 48361 ttggctggtc tcatgaccaa gcatccgatt ctggtaacgg gcggcacggg caagaccggc 48421 ggccgggtcg tgtcccgcct gcgagcgcag ggggcgccgg tccgggtggc gtcgcgctcc 48481 ggcgagccgc cgttcgactg gttcgaccgc gccacctggg acgccgcgct ggacggcgtg 48541 aaggcggtgt acctcgtacc gatcgacggg gaactcctca cccgcccgtt catcgagcgc 48601 gccgtcgaac tcggtgtcga gcgcgtcgtg ctgttgtcgg gccgcggcgt ggatgtgccg 48661 gggtactccg gcgaggccaa catcgcgggc gccacccatg tggacggtga gaccgcggtg 48721 ctcgacagcg gtatcgcgtg gacgatcctg cggcccgcct ggttcgccca gaacttcagc 48781 gagggcagct tcctggacgc gatcctcgcc ggtgagctga gactgcccgc cggggacggc 48841 gcggcctcct tcgtcgatgc cgaggacatc gccgcggtcg cggccgcggc cctcaccgag 48901 gacggccacg gtgggcagat ctacgaactc tccgggcccc gggccctgac catcgccgac 48961 gcggtcgcgg agatctccgg ggccaccggc cgcgatatcc gctacgtgcc gctgaccccc 49021 gaagagttcg tcgccgaact caccggacag ggatggtcgt cggccgaggc ggaggactac 49081 gcggaggcgg tgagcccgat ccggcgcggg atggacagcc acctgtccga cggagtgcgg 49141 cgcgcactcg gccggcagcc acgtgacttc accgactacg tgaaggcgtc cgtcaaggcg 49201 tggccgtagc actgtcgcgc aggaagccag cgaaggactg ggcggcgggg gtgagagcgt 49261 ggtcggccat gcgcaccagg aggatgcggc gcaccggggc ggggggttgc aggggcagga 49321 cgctgacgcc gccgcggatg ccctccaggg ccagggtggg ggcgagggcg acgccgattc 49381 cggcggcgac catggcctgg gcctcctggt agtcgtgggc ctcgtaggcg atctgcggct 49441 cgaaaccggc ggtgtggcaa ctgcgggcga gggcctcggc caccgggtgg tggtcggcac 49501 gggtgatcca ggggtcgttc gcgaagtcgg cgagggcggc catggggcgg tcggcgaggg 49561 ggtggtcctt gctgaccagg agggccgggg ggtcgtcggc gagtgaggtg acgacgatgt 49621 cctcgcggtc gatgcggttc cagtcgtagt cccacatcag ggacatctcg acttcccggt 49681 tctccagcat cgcccacagg cccgcgatgc gcgcgctgcg caccgtcagc cgtacgtcgg 49741 ggtgtgcttc ccggaaggcg atcacggccc gggggaggag ggaggcgccg acggtgggga 49801 aggtgccgat gcggagggtg cccgcgcgga gccccgcgaa gtcggccagc tcgttctccg 49861 cggccgtcag ttcgcgctcg atccgctccc cgcgcagcgc gagagcgcgc cccgcgtcgg 49921 tgagcgtgac gccccgtgcg tggcgctcca gcaacggttg cccggcctcc gtctccaggc 49981 ggctgacctg ctgggatacc gctgacggcg tgtagttgag cgcccgcgcg gtggcggtga 50041 ccgagccgcg gcgggcgacc tcggtgaaga gcaggatgcg tcgtacgtcg agcaccgcgc 50101 cgcctccagc gttaactcca acttaatacc cgtgcagatt tccgagattg tacttcacgc 50161 tctctgcgcc caccgtggat cacaccccgc acggaagtgc cgtcggggta tccatgagga 50221 gtctgttgtg ttgcgtctgc agggcgagat gatccgcgga ggaaccagca agtgctggat 50281 cttcgaccac cacgatgtgg tggcgaccgg tgtggacgcc gacaccctgc tgctcgccgc 50341 ctacaacgcc gccgaccccc gccagatcga cggcgtcggc ggtgcctcct ccaccacctc 50401 caaggccgcg atcgtccagg cctcggccga gccgggcgtc gatgtcgaat acgccttcgc 50461 gcaggtcggc atcggtgacg agcgcgtgga gtggaccagc aactgcggca actgcgccac 50521 cgccgtcgcc ctgtacgccg tccacaacgg cctggtgccg atcacaccgg acaccaccac 50581 ggtgcggatg ctcaacgtca acaccggcgc ccgcctcacc ggcaccatcc ccaccccggg 50641 aagcaccgcg ccccacgagg gcacagccgg ggtgccgggc accgcggcgc tcggtgtgcc 50701 ggtcctgctc ggcttcgagg acccggccgg tacgaccacg ggtcgcgccc tgccgaccgg 50761 ccgcgccctg gacaccctga ccgggcccgc cggtccggtc gaggcgtccc tgatcgacgc 50821 gggagccccg gccgcgctgt tcgaggccaa ggcgttcggc ctcgacggca ccgaatccct 50881 caccgagttc gcagcggcgg ttcccgcgct caccgcgctg cgccgcgagg ccgccctggc 50941 catgagtctg gccgaccagg gtgaaccggt gagccacgcc gttccgaagg tcggcgttgt 51001 tgcccgatct gtctcctatc acaccactca tggcactctg gtcgcaccgg acgagtacga 51061 cctggccgtg cgcatggtct ccatgcacgc accccacccg gcgatcggcc tcacctcggc 51121 cgtcgcgctg gccaccgcag ccgccatccc cggcaccctc gcccaccgcg ttgcccggca 51181 gaccgccgac ggcacgctgc gcctgggcac cccggcaggt gtcatcaccg cccaagccgt 51241 ccccgcgacg aacggcgcgt gccccacggt gctgctgcac cgcgccgccc gacgcatcgc 51301 ccgagccgaa cttctcgttc ccgtcctgga aggacgcccc gcatgagccg caacgatgcc 51361 gccccgggta ccgtcaccgc tccaccgcac cgcatccgcc ggctgctgtc cctgctctac 51421 gtccaatgcc tggtcggcgt cgtcgccggg gctgccgtcg gttggctgtg gccgtccttc 51481 ggagccgatc tgaagcccct cggcgacggc ttcatcgcgc tggtgcgcat gatgatcgcg 51541 ccgatcatct tctgtaccgt cgtccacggc atcgcctcca tgggcaacgc gcgcgccgtc 51601 ggccgggtca gcctcaaggc gctgctctac ttcgaggtgc tcaccaccgt cgccatggtg 51661 atcggtctgg tcgtcgtcaa cgtcgtccag cccggcagcg gactgcacgt cgacacctcc 51721 accctctcca ccgagggcct gcctccggag gccaccgcga gccacgagag cttcgccggc 51781 ttcgtcctcg ccatgattcc ggacaccctg ctcagcgcgc tgaccggcca cgagatcctg 51841 ccggtgctgg tgatctccgt actgttcggc ttcggtctgc acgccagtgg cgaggcggga 51901 ctgggaatcg cccggggcat cgagaagctg tccaaggtcc tgttcacgct catccgctgg 51961 gtcatgcggc tggccccgtt gggtgccttc ggctccatgg ccttcaccat cggcaactac 52021 ggcctggaca ccctgcgcca cctcttcctg ctggtcggct ccttctggct caccgcgctg 52081 ttcttcgtcc tggtcgtcct gggcacggtc atgcgcctca acggcctgcg cctgctgccc 52141 ttcctccgct acatcaggga ggagctgctg atcgtcctgg gcacctcgtc caccgagccg 52201 gtgctgccgc gcatgatggg caagctccaa cacgtgggcg cctccaagcc ggtggtcggc 52261 atcacgctgc ccgccgggta ctccttcaac ctcgacggca ccgcgatcta cctgaccatg 52321 ggctcggtct tccttgccca ggccctcggc atcgacctca gcctcaccca gcagctgtcc 52381 atgctcgccg tcatgctgct cacctccaag ggcgccgccg gggtcaccgg ttccggcttc 52441 atcgccctgg ccgccaccct cagcgccgtt ccgcacgtgc ccgtcgccgc cctggcgctc 52501 atcttcggca tcgaccgctt catgtccgag gcccgcgccc tgaccagcct ggtcggcaac 52561 ggtgtcgcca ccctggcggt ggccaaatgg gaggggcagc tcgacgagga ccgtgccaag 52621 gccgtcctcc gcggcgacat cccgtacccc tcgggtcccg aggccgggcc cgtccccggt 52681 gagaagcccg tggacgacgg cccgaaggca acggccggaa ccgaccgcga ccccgtggcg 52741 gccgtcggct aaggggagcc gtcggggcgg aggaccaggt cgagcagccc ggggaagcgc 52801 gcgtcgaact cctcgcggcg cagccggttg acccgcctcg gcccctggtc gcgctgttcc 52861 accagaccgg cgccgcgcag gaccgagaag tggtggctga gcgcggcctt gccgacggac 52921 acgtcgaagc tgccgcaact gcgcgtccat tcggcggagc ccgccagctc gcggaccagc 52981 tggatccgta ccggatcggc gagcgcggac agtgcggtca ggacggacac ctcggcgggg 53041 tcggtgtgca ccggtgcggc gcggtgaccg ctccccgtgg cctggctcgc catgtgcccc 53101 tccgatcacc ttgcccggtg ttcgatgaat atcttacagt ccccagtgtt cgcttttcat 53161 tgaacaccag cttttcatcg aacactgccg gaagggtgtg ttccgtatgc gtacggtcgc 53221 gttccaggaa tacggaggcc ccgaggtgct tcaggtcgtc cgggccgaac ccccggagcc 53281 ggggccgggc caggtcacca tcgacgtcgc ctacgcgggc gtgaacttcg cggacctcaa 53341 ggcgcgcgcc gaggggtacc gggtggcgtc gctgccctac gtccccggtc tggaggtctc 53401 cgggcggatc cgggccgtcg gccccggtgt cgaggggctg cgcccggggc aggacgtcgc 53461 cgccctcgtc ggcggtggcg cgtacgcgga ggtggtggcc gccgaagccg ccaccgtctt 53521 cccgctcccc gagggcctgg acctgcggac cgcggccacg ctccccaccg tgctgcccac 53581 cgcgcacgcg ctcctccacg aggtggggcg gctgcgcgcc ggggagagcg tgctggtgca 53641 cggcgccgcc ggaggcgtcg gcacggtggc cggacagctg gcccgggcgg cgggcgcggg 53701 tgcggtgtac ggcgtggtct cctcggcggc caaggccggg cacgctctgg agcacggcta 53761 cgacgaggtg ttcaccacgg acaccttccc cggcgacgtc caccgcgcca ccggcggcag 53821 gggcgtcgac ctggtcctcg acccggtcgg cggggacacc ctgcgccgcg gcctcgacgc 53881 gctggccgtc ttcgggcgcc tggtgtcctt cggcaacgcg agcggggccg agccgtggca 53941 cgcggggcag gcggacctcg ccgcgcgggg ccgttccgtc gcgggcttct ccatcctggc 54001 cctcgcgcag accgcgcccg aggcgctgcg ctcgctcacc gaacgcgcct tccgcacggc 54061 caccgacggc accgtgacgc ttccggtcac cgcggagttc ccgctggcgg acgcggccga 54121 ggcccaccgg ctgatgggcg ggcgcacctc cacgggcaag ttgctgctgc ggatggccga 54181 ttgaacgcga ccgccgtgcg caagccgatg gagatgtgga ccgagaatga ctgacagcag 54241 cgtgacccgg ggcttcacca gggtcgcggg gaacataccc gctcccgcgc tcgtgctggg 54301 cggtgtgtgc ggcatccagt tcggcgcggc cttctcgccc cagatatacc cgcaggtggg 54361 cgcgccgggc gtggtgttcc tccggctgct gatcgcgggt gtgctcctgt gcctggtgtg 54421 gcgcccgcgg cggcaggcgc tggactcggt gaagggcgcg tgggggacgg tgatcggcgc 54481 cggggccctg ctggcggggc atcacctcgc gttctacgag gcggtgaacc acatccccct 54541 gggggcggtg gctacgatcg agttcctcgg cccgttcgcc atcgccctgg ccggatcgcg 54601 gcgagcggtc gacctcctgc ccgcctgcct ggcggccgcc ggtgtcctcc tgctcggcgg 54661 tggcggcgtc cccctcgacc cgggtggcct ggccctggcc gcggtggcgg cgtgctgctg 54721 gggcggctac atcctggtct cctcccgcat ggcacgacgc ctcagcggcg gccagggtct 54781 ggcactggcg gtgctgtggg cggcgctgct gagcaccccg tacggcctcg tccgcgccgg 54841 gagcgccgtc ctggaccccc atgtgctgtg ggtggccgcc gtggtggcgg tggcgtccag 54901 cgtgctcccg tactcgctca acctggaggc gctgcgccgg atcccgccac gggtgttcgg 54961 cgtgctgaca agcctggagc ccgccgccgg tgccctcttc ggactcctca tcctcggtca 55021 gcggctcgcc tggccgcagt ggctcggcat cgccgcggtc gcctgtgcct ccgtcatcgc 55081 gacgttcctg ggggccgggg gacggcggaa ctcccgggtg agggccaaga gcgcctcgcc 55141 ggatgccggg cagcctgcgc tgtgtgagac cggcccggcg aggtgatgca cggcgcgccg 55201 tcgacacccg cgtccatgat cgcggtcatg gtcgagcggg gtggcgtgcg gcggcctccc 55261 ggacttcttc cgtaaggcgc tggcgcgtcg aggagcgcct gacggtcgat gaagtggctg 55321 cggggcgcgc ctccgccatc cccgacgcgc tcgccttcga gcaggcggcc gtcctgccgc 55381 tcaccctctc gaccgcggcc accggcctgt tccagcagga ccacctcgga ctcgcccgcg 55441 gggggacaac gcggtcggtc ccgcgatcta cgccggcttc ctcccggcgg ctctcgccac 55501 cggcgcctat cgcgccgcac cggacgcggt cgtcgtcggc gtcggccacg gactcgaccg 55561 cagatcggag aggtcacccg gagccatcag gatccgtact acaggcatgg gtcttcctga 55621 tgtgcccttc tttcccgggc cgcgccggac ctagtgtcca gcggaacacg gtccatgccg 55681 gaccggttcg cgtgagcgtc cgacgccgtt cggacgtcgt cccgacccct gcgggaaagg 55741 agcctcactg tgcctgttgt cgatctggtg gccgacctcg gagagagttt cggggcctac 55801 accatgggca atgacgccga gctgctggat cttctcacct cggcgaacgt cgcgtgcgga 55861 ttccacgcgg gcgatccgcg ggtgatggac gcgacggtgc gttcctgcgt ggagcgtggc 55921 gtcggcgtcg gcgctcatcc gagctttccc gatctggtgg gcttcgggcg ccgggcgatg 55981 gacctggcgc cgaacgaggt gcgcaccgac gtcctgtacc agatcggggc gctgtccgcg 56041 ttcacctgcg cgcacggcac ccgcatcaac catctggcac cgcacggccg cctcggcaac 56101 ctcgtggtcg tccggcggga ctacgccgag gcggtggcgg acgcggtgga ggcgttcgac 56161 ccgtccctcg tgatcctgat gcaggagggc gagatggcgg ccgtcgcgcg tgagcggggt 56221 ctgcggatgg ccatggtggg catcgcggac cgggcgtacg aggacgacgg caccctggtg 56281 tcccggtccg agcccggcgc cgtgctccac gacccggacg aggtcacccg ccggaccatc 56341 cgaatggtga ccgagggcgt gatcaccagc cgccacggta cggacctgcc ggtccgcacg 56401 gactgcgtcc agctgcacgg cgacggtccc gcggcgctgg agctggcgcg gcgcatccgc 56461 ggcgaactgc tggaggccgg agtcggactg gcgccactgg acgaggtgct ggatgcccgc 56521 gctcaggcgg catgagccga gcgccatgac ggtcatgcgg acgacggcca agatcgacat 56581 atcgccgtgc ggtgacgccg cgctgcgggt caccgtcgac ggcgacgaca ccgacgtggt 56641 gtgggcggcc gtgcaccggc tcgcgggatg gctgaaccgt ggcgacatcc accccacggt 56701 gtccgccgtg ccgacgtacg acgcggtgct cgtggagttc gacccgtacc acaccacggg 56761 cgacgcgatc atgtcgtaca tccgctcctg ggacgccgcc cccgacgtgg cgagcgcggt 56821 gccgtccggg gtcatcgacg tgccggtgct gttcggcggc gacgcgggtc ccgacctgga 56881 atgggtcgcc ggtgtggtgg gtgcgtcggt ggcggaggtc gtccgcctcg tctgcgcgaa 56941 ggagcacctc atccgctgtc tcggcgggcc cgccgcgtcg gccatgacgg acgggccgga 57001 attcggggtc cccgttcccc ggctcgccac gccccggctg cgggtgccgc cgggcgcgat 57061 ctccgtcgcg ggacgtcagg cggtgatcgg gcccgtcgcc gcgccgagcg gctggcggca 57121 gatcggccgt acgccgctga ccatcctgcg gaccgatggg agcggccaca ccggcagcga 57181 ctccgtcgtg ccgtaccggc ccggggaccg ggtccggttc ttcccggtcg acgagggcac 57241 gtacgccgcc ctgctcggcg tcccgatgcg gtaccggaac catgactgac cgccccgagc 57301 tgtccgtgga ggccgcgacg gcgtgcgtgg tcaccgacct cggccgcacc tcaggacccg 57361 cgcgcggtct cgcggtcaac ggcgcgctcg accagttcgc cgcgcgcgcc gcgaacgccc 57421 tggtcggcaa cgcgccgacc gcaccgctca tcgaggccac cggtttcggt gtcacgctcc 57481 ggcccagcca cgacatcctc ctggccgtca ccggcgcgcc cgccgaaccg gccgtcgacg 57541 gactgccgca ccccgcgtgg tcaccgctgt cggtgcgggc gggggagacg gtgcgggtgg 57601 gcatctccga tgcggggctg cgcgcgtacg tcgccgtgca cgggtcgttc gacgtgccga 57661 tgctgatggg gagctgcgcg ccggactcga tgatcgagtt cggcaccccg gtgaccgccg 57721 gtatgtccct caccctgcac cgctcccacc caccgctggt caaccggcgt ttcggggcca 57781 cggtcttcga cttcggcatc ccccgcgaca tcggccgggt gcccgcggtg ctggatgtga 57841 tcgagggacc cgacgccgcg gagttcggca ccgggctcca gcggctcttc gactccccgt 57901 acacggtcac cccacggatc aaccatgtcg gcctccgcgt ggccgggcat gtgccgcagc 57961 gcaccgtcac cggggaggtg ctgtcgcggg gcgtgccggt cggggcggtc gaggcccccg 58021 cgggcgatga gctgctcgtc ctgatgcgcg gccgcgggat caccgcgggc tacccggtgc 58081 tcgcggtgct cacctcgcgc gccctggatg tcgcggcgca gctcaggccc gggcaggaga 58141 tccgcttccg ccggaccagc gccaccgcag ccaccgccgc ctatctggag cggcggcggc 58201 tcctggaccg ggtcgcgctc cgcgcgcgca ccgccttcgc cgcactctcc tgaccacacc 58261 actccgctga caccaccatc cactgcacac gcaccatcga aggaggaaag ggatgtcctt 58321 tcccgacgta ctgcgcaccc ccgtgctggc cgagcggatg tcgcgcgtca aggaatcgcc 58381 cagttcccgg gtcgcggacc gggtgcgcgc ttttcaagcg gcgggccgca aggttcttcc 58441 gctgacgatc ggtgagcccg atttcgatac gccggaccat gtgaaggacg cggcgatcaa 58501 ggcaattcgc gagggcgaga cgaaatacac ctcggcgaac ggcacgcccg cgctccagaa 58561 atcgatcatt tcccggctgg agcgcaagac cggacagtcc tacggcaccg gcgagatctg 58621 cctgggcggc ggcgccaagc agctgatctt cctggcgttc gtggcgacgc tcgacgaggg 58681 cgacgaggtg atcgtcccgg cgccgtactg ggtgtcg //