LOCUS NZ_GG657754 12382 bp DNA linear CON 01-MAY-2024 DEFINITION Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome shotgun sequence. ACCESSION NZ_GG657754 VERSION NZ_GG657754.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces himastatinicus ATCC 53653 ORGANISM Streptomyces himastatinicus ATCC 53653 Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group. REFERENCE 1 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D., Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Annotation of Streptomyces hygroscopicus strain ATCC 53653 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA REFERENCE 3 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Arachne v. April 2007 Genome Coverage :: 6x Sequencing Technology :: ABI ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_000158915.1-RS_2024_05_01 Annotation Date :: 05/01/2024 03:02:38 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.7 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 9,680 CDSs (total) :: 9,608 Genes (coding) :: 8,720 CDSs (with protein) :: 8,720 Genes (RNA) :: 72 rRNAs :: 4, 1 (5S, 16S) complete rRNAs :: 4, 1 (5S, 16S) tRNAs :: 64 ncRNAs :: 3 Pseudo Genes (total) :: 888 CDSs (without protein) :: 888 Pseudo Genes (ambiguous residues) :: 0 of 888 Pseudo Genes (frameshifted) :: 423 of 888 Pseudo Genes (incomplete) :: 530 of 888 Pseudo Genes (internal stop) :: 36 of 888 Pseudo Genes (multiple problems) :: 97 of 888 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 20:01:42 NOTE :: This is a single region extracted from a larger record! Orig. start :: 6601727 Orig. end :: 6614109 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to GG657754.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation was added to the scaffolds in August 2010. FEATURES Location/Qualifiers region 1..12382 /candidate_cluster_numbers="1" /contig_edge="False" /product="RiPP-like" /region_number="26" /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))" /tool="antismash" cand_cluster 1..12382 /candidate_cluster_number="1" /contig_edge="False" /detection_rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))" /kind="single" /product="RiPP-like" /protoclusters="1" /tool="antismash" protocluster 1..12382 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="False" /core_location="[5000:7382](-)" /cutoff="20000" /detection_rule="(strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))" /neighbourhood="5000" /product="RiPP-like" /protocluster_number="1" /tool="antismash" proto_core complement(5001..7382) /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))" /neighbourhood="5000" /product="RiPP-like" /protocluster_number="1" gene 1163..2413 /locus_tag="SSOG_RS57565" /old_locus_tag="SSOG_05576" CDS 1163..2413 /NRPS_PKS="Domain: AMP-binding (12-312). E-value: 9.7e-44. Score: 141.5. Matches aSDomain: nrpspksdomains_SSOG_RS57565_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF012711.4" /locus_tag="SSOG_RS57565" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05576" /product="AMP-binding protein" /protein_id="WP_050799990.1" /sec_met_domain="AMP-binding (E-value: 1.2e-39, bitscore: 135.2, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MPRHANLAEALRERARDGGDHTVALAHPDGTGGERRISYAELDAR AAAVAAWLRGRDAAGRRVLIVLDPGPHIAAALLGCLYAGAVAVPVPAPTASRTAAERTA AIAKDAAVDLVLTETAHATETSRRLSLVGRADLTCLPVDRLGPDGGTGHTSDAPSARTD PDSLALLAYDSGPATAPRGARLTHGNLLAAMHALRATLGTGPRSRIGGWLPRRHTPGLI GQVLHPLWLGATAVPLPARPFRTDPAAWLRAISRHGITEAVAPDTQYARCAALTADEQP AGLDLSRWRTALNAGEPVSSATMAAFTRRYAAAGLRTGTPGRRIRPRRRRAPAARRGPG PRCPARSSASSTRSSCRRLTGGGRRGRSGRAAPPSPPATGGGRRTPCRSSPPGPPTARA DSCAPATSASPRAAASA" aSDomain 1199..2098 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS57565_AMP-binding.1" /evalue="9.70E-44" /label="SSOG_RS57565_AMP-binding.1" /locus_tag="SSOG_RS57565" /protein_end="312" /protein_start="12" /score="141.5" /specificity="substrate consensus: X" /tool="antismash" /translation="ERARDGGDHTVALAHPDGTGGERRISYAELDARAAAVAAWLRGRD AAGRRVLIVLDPGPHIAAALLGCLYAGAVAVPVPAPTASRTAAERTAAIAKDAAVDLVL TETAHATETSRRLSLVGRADLTCLPVDRLGPDGGTGHTSDAPSARTDPDSLALLAYDSG PATAPRGARLTHGNLLAAMHALRATLGTGPRSRIGGWLPRRHTPGLIGQVLHPLWLGAT AVPLPARPFRTDPAAWLRAISRHGITEAVAPDTQYARCAALTADEQPAGLDLSRWRTAL NAGEPVSSATMAAFTRRYA" CDS_motif 1394..1432 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS57565_0001" /evalue="7.10E-03" /label="NRPS-A_a2" /locus_tag="SSOG_RS57565" /protein_end="90" /protein_start="77" /score="10.1" /tool="antismash" /translation="LGCLYAGAVAVPV" CDS_motif 1562..1591 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS57565_0002" /evalue="7.50E+01" /label="NRPS-A_a2" /locus_tag="SSOG_RS57565" /protein_end="143" /protein_start="133" /score="-2.0" /tool="antismash" /translation="RADLTCLPVD" CDS_motif 1847..1876 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS57565_0003" /evalue="5.80E+00" /label="NRPS-A_a2" /locus_tag="SSOG_RS57565" /protein_end="238" /protein_start="228" /score="1.3" /tool="antismash" /translation="LWLGATAVPL" gene 2320..2817 /locus_tag="SSOG_RS57570" CDS 2320..2817 /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS57570" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /product="hypothetical protein" /protein_id="WP_050799991.1" /transl_table=11 /translation="MPLFAARAADGPGGFLRTGDLGLAAGGGIRMTGRVHDGLLVDGVT LHPQDVERELLGCGRALGSARVFCAGPGAGPLVVVQEVRTAGAARTGLPRLAARIRARV AEEFGVTTGAVLLVRPGTVRRDGAVKVRRAVLREWYLRGELRALHADYAPAPTEPCRGG AA" gene 2937..3542 /locus_tag="SSOG_RS28195" /old_locus_tag="SSOG_05577" CDS 2937..3542 /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_process="GO:0000160 - phosphorelay signal transduction system [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family DNA-binding response regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009717663.1" /locus_tag="SSOG_RS28195" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05577" /product="response regulator transcription factor" /protein_id="WP_009717663.1" /transl_table=11 /translation="MVRVLIAEDMHMLRKALVALLEFEPDIEVVAEFSSGADILPQARQ LRPDVAILDIDLPGMDGLTAAAELHTAVPECRTMMLTSLGRPGNLRRALAAHVAGFLLK DSSPATLCDAIRAVARGERVIDPQLALAALDDGPQPLTPRELEVLRMASEGEEAARIAA RLFLSVGTVRNYLTSAVTKLDARNRVDAIRIAREAGWL" misc_feature 2953..2969 /note="TFBS match to NuR, Nickel-responsive regulator, confidence: weak, score: 19.79" /tool="antismash" gene complement(3600..4850) /locus_tag="SSOG_RS28200" /old_locus_tag="SSOG_05578" CDS complement(3600..4850) /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]" /GO_function="GO:0046983 - protein dimerization activity [Evidence IEA]" /GO_process="GO:0000160 - phosphorelay signal transduction system [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1048: sensor histidine kinase" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014179409.1" /locus_tag="SSOG_RS28200" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05578" /product="histidine kinase" /protein_id="WP_245606398.1" /transl_table=11 /translation="MPDDAGKKPPRDHDDLAPRLAVVITVVVLLGYFTVAVTYVVEGLP PGSAVDAVVRMLEVLPLLAALLGIQLLHSFPGLAPRLAAGRHWTLLLQAMLTFLPFAVF EQAWLGMPGFLAGSGLLVLAPAVAWPTFAAILVITDVLLFQVGFGWDKVAYTTVSTTIT GLVVFGLSRLSGLVAEVSRSRAELARLAVAQERLRFSRDVHDLLGLSLSTITLKCELVH RLVPRQNDRAQQELAEILQTSRQALADVRAVASGYRTMSLSAEAETARSMLAAAGIRAT ADIDCGPLPERVDTVLASVLREGLTNVLRHSKADHCAITARRSGPTVRLTLVNDGVGKP STILRADSVAGAAGTDGGSGIGNLRVRLSGLGGRLYADVRSDGRFELRAELELSTQAPR GGRGRGTEEERGPAVPG" gene complement(5001..7382) /locus_tag="SSOG_RS28205" /old_locus_tag="SSOG_05579" CDS complement(5001..7382) /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) RiPP-like: TIGR03604" /gene_functions="biosynthetic (rule-based-clusters) RiPP-like: YcaO" /gene_functions="biosynthetic-additional (rule-based-clusters) Cyanobactin_D_RRE" /gene_functions="biosynthetic-additional (rule-based-clusters) Goadsporin_CD_RRE" /gene_functions="biosynthetic-additional (rule-based-clusters) NHLP_CD_RRE" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014060947.1" /locus_tag="SSOG_RS28205" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05579" /product="TOMM precursor leader peptide-binding protein" /protein_id="WP_039938896.1" /sec_met_domain="Cyanobactin_D_RRE (E-value: 8.4e-13, bitscore: 47.3, seeds: 10, tool: rule-based-clusters)" /sec_met_domain="Goadsporin_CD_RRE (E-value: 9.6e-19, bitscore: 66.4, seeds: 8, tool: rule-based-clusters)" /sec_met_domain="NHLP_CD_RRE (E-value: 8.1e-16, bitscore: 56.9, seeds: 8, tool: rule-based-clusters)" /sec_met_domain="YcaO (E-value: 3.3e-82, bitscore: 276.0, seeds: 127, tool: rule-based-clusters)" /sec_met_domain="TIGR03604 (E-value: 5.3e-72, bitscore: 241.8, seeds: 25, tool: rule-based-clusters)" /transl_table=11 /translation="MTGELGFTPHLRVEPVPGEAVYLVSEHGVTALHGRAIAALAPLLD GSRDLAHILTEAARAAGLPGAVPAGQAERVIARLRAAGLVSEREPTHAPGPEEAYWELA SLGGGDGRSIRPAARPAAASVASVILGSADPAEVLRALRAAGLRAAGPADAEGAGDDRA AAPAAQGRECRWAVRQVGPRQHGAAELTLVVCDDYLDPRLAAVDAAHRAAGRRWLPVKP VGTRAWLGPFLGAPEDPCWACLADRLWRGRQAEAYLQRRLGRPGPVPRPPASLPASRAA ALQLAALEAAKWLAGHRHPGQQALCTLDSLTATVDRHPLARRPQCPGCGNPALVAERIR APLAVPSPREPHENHVDATDDASPRRVMERYGHLVDPVTGLVTEIRRDPRGPAFLNCYH ARHPSYAAYATSPGGLDAVRAGLGAAAHGKGRTAEQARASALCEALEHYSGHFQGDEPR QRARYRALDPADAVHPDTVQLVDPRQLARPYPDQRAPRHRLPDPFDEDAELDWTPVWSL TAERHRLLPTALLYYGAPQPPGRRCCRADSNGAAAGSTLADAVVRGFLELVERDAVALW WYNRTRQPALPLDAFDDPWLAELRRAHGGLRREVWALDLTTDFGIPVVAALSRRTDKPA EDITLGFGAHFDRHAALCHAFAELNQMLPAVVEARADGGGYGAADAEALRWFRTATTAN GPYLTPDPDAVPPPGMAAPPDGDALAAVREAVRARGMELLVLDQTRPDVGLPVAKVLVP GLRPHWPRFAPGRLYDVPVALGRLRRPTAYRDLNPVPLFL" aSDomain complement(7065..7373) /aSDomain="Goadsporin_CD_RRE" /aSTool="RREfinder" /database="RREFam.hmm" /description="RRE-containing CD fusion protein in a goadsporin cluster" /detection="hmmscan" /domain_id="rrefinder_SSOG_RS28205_Goadsporin_CD_RRE.1" /evalue="2.80E-21" /identifier="RREFam013.1" /label="SSOG_RS28205" /locus_tag="SSOG_RS28205" /protein_end="106" /protein_start="3" /score="66.4" /tool="antismash" /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGRAIAALAPLLDGSR DLAHILTEAARAAGLPGAVPAGQAERVIARLRAAGLVSEREPTHAPGPEEAYWELASL" aSDomain complement(7077..7373) /aSDomain="NHLP_CD_RRE" /aSTool="RREfinder" /database="RREFam.hmm" /description="RRE-containing CD fusion protein in a NHLP/Nif11 LAP cluster" /detection="hmmscan" /domain_id="rrefinder_SSOG_RS28205_NHLP_CD_RRE.1" /evalue="2.40E-18" /identifier="RREFam015.1" /label="SSOG_RS28205" /locus_tag="SSOG_RS28205" /protein_end="102" /protein_start="3" /score="56.9" /tool="antismash" /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGRAIAALAPLLDGSR DLAHILTEAARAAGLPGAVPAGQAERVIARLRAAGLVSEREPTHAPGPEEAYWE" aSDomain complement(7128..7373) /aSDomain="Cyanobactin_D_RRE" /aSTool="RREfinder" /database="RREFam.hmm" /description="RRE-containing D protein in a cyanobactin cluster" /detection="hmmscan" /domain_id="rrefinder_SSOG_RS28205_Cyanobactin_D_RRE.1" /evalue="2.50E-15" /identifier="RREFam007.1" /label="SSOG_RS28205" /locus_tag="SSOG_RS28205" /protein_end="85" /protein_start="3" /score="47.3" /tool="antismash" /translation="ELGFTPHLRVEPVPGEAVYLVSEHGVTALHGRAIAALAPLLDGSR DLAHILTEAARAAGLPGAVPAGQAERVIARLRAAGLV" gene complement(7396..7596) /locus_tag="SSOG_RS28210" /old_locus_tag="SSOG_05580" CDS complement(7396..7596) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS28210" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_05580" /product="hypothetical protein" /protein_id="WP_039938898.1" /transl_table=11 /translation="MTEASIPPQPAADGGVPAAPDPDPDPNALDALDDLHDLDDLVIED LTGASWPAVAPRICICTFGGE" gene 7846..8670 /locus_tag="SSOG_RS28215" /old_locus_tag="SSOG_05581" CDS 7846..8670 /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1041: transcriptional regulator, SARP family" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014060945.1" /locus_tag="SSOG_RS28215" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05581" /product="AfsR/SARP family transcriptional regulator" /protein_id="WP_009717667.1" /transl_table=11 /translation="MDIKVLGPLSVEACGQSIVPSAGKPRQILALLSVYANQMLPVPTL MEEIWGTQMPRSAPTTLQTYILQLRRRLAAAYGPQAPQASKDVLATRYGGYVLEAQPGA VDIHEYDRLVAAGRDALDAGDDVEASLLLREALAVWRGPALVDVRVGPVLEIELARLEE SRLGVLERRIEADLRLGRHAELLTELTELTARHPLHEGLHAQCMAALYRAGRPWQALEV YQGLRARLVEDLGLEPSPRLQKLQQAVLASDPALDLDLEGHWRRPVLDLFAA" gene <9035..9607 /locus_tag="SSOG_RS28220" /pseudo="" CDS <9035..9607 /GO_function="GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014179413.1" /locus_tag="SSOG_RS28220" /note="incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /product="cyclase family protein" /pseudo="" /transl_table=11 /translation="TPVDAPVPCGASGARGMSRVIDRMPMEWFLRPAHVLDITGADPDT RTAGVEDIEKALARTGCRPRPLDVVLLHTGAACWAGTPRYFTDFTGLDGPATDYLLDLG VRVIGTDAFSLDAPFHDMIRRYHATGDRSALWPAHFAGRRREYCQIERLARLDTLPSTG FRVACFPVKTAGAGAGWTRAVALLDEV" gene 9613..10860 /locus_tag="SSOG_RS28225" /old_locus_tag="SSOG_05582" CDS 9613..10860 /GO_function="GO:0071949 - FAD binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1050: monooxygenase FAD-binding" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014060944.1" /locus_tag="SSOG_RS28225" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_05582" /product="FAD-dependent monooxygenase" /protein_id="WP_039938899.1" /transl_table=11 /translation="MATAHQEIDTEVCVVGGGPAGLVLALLMLRSGARVTVLERSRAHE RETRGEILQPGAQALLDELGVLAGARARGAQEHDRFRLFEGDRMLLEADYRLLPAPYDH LLSLPRTHLLDELLAHCRRSPGFRYLPGRRVGGLVWRDGRIAGVTADGPDGRCTVRARA VVGADGRYSRVRRLAGIGAGRTEALHHVLLWCTLRAGGADAPPLRDVRVFRTGDGPVVV YGSWPDRIHLGWTLPQHGHRALTALGPDRVRERLARAVPPYATAIREQIRALGDLGLMD VFSARARRWVDDGLVLIGDAAHTHGPIAAQGITLAIQDAVVLHPVLAGALAAGDVGADR LAAFEGRRGPDVAAVVRMQTRQSRALLSGGAFATRVRPYLARALRHTPLHRRMLQRIAY GGPAIRVMDARACGRP" misc_feature complement(11902..11917) /note="TFBS match to RutR, Regulator of the pyrimidine and purine metabolism, confidence: weak, score: 19.64" /tool="antismash" ORIGIN 1 tcttcctgtc cttcccggac gccgcccccc aggtcacccc cgcccggctg gccgccgacc 61 acacccccgc gaccggcgac ttcttccagc gcgcctccta cgggcgcttc tcgctgcgcg 121 tccacccgct gcggcgctgg atcaccatgc cgaaggcgtc caccgcgtac gccatacagc 181 gcgactggaa ctccgcgcgc cgcgccgcgt atctgcgcga cgccatccgc gccgccgatc 241 cgcacctgga cttcggccgc tacgacatcg tgtatctggt cgccgacccc gatgccccgg 301 gcgtcgacgc cgacgcgacc aaagtggtca acttcgaacg gcccctgcgc gccgacggta 361 aggatctgcg ccgcctggtg actgtcttcg agcaccatcc gcccgatcgc aatgtcctcg 421 cccatgagac cgggcacgtc ttcgacctgc ccgacctcta ccaccggccc agcaccgccg 481 acaacagcgg cgactgggac acctacgtcg gcgactggga cctgatgggc agccagttcg 541 gactgtcccc ggaccccttc ggctggcaca agtggaaact cggctggctc accggccggc 601 aggtggtctg cgcccgggcc ctcggcccga agatgtacac cctccagccc ctcagcgccc 661 ccatggaggg ccgccccggc gccgacaccc gcacccggct gatcgtggtc cgcaccggcc 721 ccaccaccgc cctggccatc gaggcgcgcg gcgcgtacgg caacgacgcg ggcacctgca 781 ccgaaggcgt cctggtctac cgggtacgca acgacgccgc ctccggcgag ggcccggtcc 841 gggtgctgga cggccacccc gccacctcgg cctgctggaa cgagtccgtc taccccgagc 901 tggccgacgc cccgcttggc gtcggcgact ccctcctggc cagggaggaa gcggtccgcg 961 tgaccgtcac cggccgcgcc accggaggct cctgggccgt ccaggtcagc cgcggcgagc 1021 gcgactagaa cggctgcgga cgtctcctga accggtcgac accgtagcgc aggtcccggc 1081 acccgaacgg tgatcaagca gcgttcgagg tggcgctccg agactgtggc ctcgttttga 1141 tctccggcgc ccgggagcga ccatgccacg acacgcgaat ctggccgagg cactgagaga 1201 acgggcccgg gacggcgggg accacaccgt ggcgctggcc cacccggacg gaaccggcgg 1261 cgagcggcgg atctcctacg ccgaactcga cgcccgcgcc gcggccgtcg ccgcctggct 1321 gcgcggacgc gacgccgccg ggcgccgggt gctcatcgtc ctggaccccg gcccgcacat 1381 cgcggccgcc ctgctcggct gcctgtacgc gggcgccgtc gccgtccccg tccccgcgcc 1441 cactgcctcc cgcaccgccg ccgagcgcac cgcggcgatt gccaaggacg ccgccgtgga 1501 cctcgtcctc accgaaaccg cgcacgccac cgagacctcg cgccgtctct ccctcgtcgg 1561 ccgcgccgac ctcacctgtc tgcccgtcga ccggctgggg ccggacggcg gcaccggcca 1621 cacctccgac gccccgtccg cgcgcaccga ccccgacagc ctcgccctgc tggcgtacga 1681 ctccgggccc gccaccgccc cgcgcggcgc ccggctcacc cacggcaacc tcctcgccgc 1741 catgcacgcc ctgcgcgcca ccctgggcac cggaccccgc tcccggatcg gcggctggct 1801 gccccgccgc cacacccccg gcctgatcgg gcaggtgctg cacccgctgt ggctgggcgc 1861 caccgccgtc ccgctgcccg cgcgcccgtt ccgtaccgac ccggccgcct ggctgcgggc 1921 catcagccgc cacggcatca ccgaagccgt cgcccccgac acccagtacg cccgctgcgc 1981 cgcgctgacc gcggacgaac agcccgccgg gctcgacctc tcccgctggc ggaccgcgct 2041 caacgccggg gagccggtct cgtccgccac catggccgcc ttcacccgcc gctacgccgc 2101 cgcggggctg cgcaccggaa cccctggtcg ccgtatacgc ccccgccgaa ggcgcgcccc 2161 tgctgctcgc cgagggcccg gcccccggtg cccggcgcgg agttcggcgt cgtcgacccg 2221 ctcatcttgc cgtcgcttga ccggaggagg ccgtcgggga agatctgggc gcgcggcgcc 2281 gccgtcgcca ccggccactg ggggcggccg ccggacaccg tgccgctctt cgccgcccgg 2341 gccgccgacg gcccgggcgg attcctgcgc accggcgacc tcggcctcgc cgcgggcggc 2401 ggcatccgca tgaccggccg ggtccacgac ggactcctgg tcgacggcgt caccctgcac 2461 ccccaggacg tcgagcgcga actcctcggc tgcgggcggg ccctggggtc ggcccgggtg 2521 ttctgcgcgg gcccgggcgc cgggccgctg gtcgtcgtcc aggaggtccg tacggcgggc 2581 gccgcccgga ccggactgcc tcggctcgcc gcccggatcc gggcccgggt ggcggaggag 2641 ttcggcgtca ccaccggcgc ggtgctgctc gtccgccccg gtacggtgcg ccgggacgga 2701 gcggtgaagg tgcgccgcgc cgtgctgcgc gagtggtatc tgcgtggtga actgcgcgcc 2761 ctgcacgcgg attacgcgcc cgcacccacc gaaccgtgcc ggggcggcgc ggcctgaaca 2821 acggccgcgg taatactgct gttcgacaag agaatcgggc ggaaagagct gcgaggcccg 2881 gaaacacggg ggaataatcg tcctgcgggg gccggtgggg gaaggggcag ggcgaaatgg 2941 tcagagtgct cattgccgaa gacatgcata tgctgcgcaa ggcactggtc gccctgctgg 3001 aattcgaacc cgatatcgag gtcgtggccg aattctccag cggcgccgat attctgccgc 3061 aggcccgtca gctccgcccg gacgtcgcga tcctcgacat cgacctgccc gggatggacg 3121 ggctgaccgc cgccgccgag ctgcacacgg ccgttcccga atgccggacc atgatgctca 3181 ccagcctcgg caggcccgga aatctgcggc gcgccctcgc ggcccatgtc gccggatttc 3241 tgctgaagga cagcagcccg gccaccctgt gcgacgccat tcgcgcggtc gcgcggggcg 3301 agcgggtcat cgatccccaa ctcgccctgg ccgccctgga cgacggcccg cagccgctga 3361 ccccgcgcga actggaggtg ctgcggatgg cctccgaggg cgaggaggcc gcccgtatcg 3421 cggcccggct ctttctctcg gtggggacgg tgcgcaatta cctgacctca gccgtcacca 3481 aactcgacgc gcgcaaccgg gtcgacgcca tccggatcgc ccgcgaggcg ggctggctgt 3541 agcgggcgct tccgcagcgg gcctcatacg gaggccgaac gctacgccgc ggcccggcgt 3601 caccccggca ccgccgggcc ccgctcctcc tccgtaccgc gcccccgacc gccgcgcggc 3661 gcctgggtgg acagctccag ctcggcccgt agctcgaacc ggccgtcgga ccgtacgtcc 3721 gcgtacagcc gcccgcccag gcccgacagc cgcacccgga ggttgccgat cccgctgccg 3781 ccgtcggtgc ccgcggcacc ggcgacgctg tcggcgcgca ggatggtgga cggcttgccc 3841 accccgtcgt tcaccagcgt cagccgcacc gtgggccccg accgccgggc cgtgatcgcg 3901 cagtggtcgg ccttgctgtg ccgcagcaca ttggtcagcc cctcgcgcag cacgctcgcc 3961 agcaccgtgt ccacccgctc gggcagcggc ccgcagtcga tgtccgcggt ggcgcggatg 4021 cccgccgcgg ccagcatcga ccgggccgtc tccgcctccg cggacagcga catcgtgcgg 4081 tagccgctgg ccaccgccct tacatcggcc aacgcctgac gggaggtctg gaggatctcg 4141 gccagctcct gctgcgcccg gtcgttctgc cggggcacca gccggtgcac cagctcgcat 4201 ttgagggtga tggtggagag gctgaggccg agcaggtcgt ggacgtcccg cgagaaccgc 4261 agccgctcct gcgcgaccgc cagccgggcc agctccgcac gcgaccggga gacctcggcg 4321 accagcccgg agagccggga gaggccgaag accaccagcc cggtgatcgt ggtggacacg 4381 gtggtgtacg cgaccttgtc ccagccgaac ccgacctgga acagcagcac atcggtgatc 4441 accaggatcg cggcgaacgt cggccaggcc accgccggag ccagcaccag cagcccggag 4501 cccgccagga aaccgggcat gcccagccac gcctgctcga agacggcgaa cggcaggaag 4561 gtcagcatcg cctggagcag cagcgtccag tgccgtccgg cggccagccg gggcgcaaga 4621 ccggggaagg agtgcagcag ttggatgccc agcagcgcgg ccagcaacgg caggacctcc 4681 agcatccgca ccaccgcgtc caccgcgctc cccgggggga gcccttcgac cacatacgtc 4741 acggcgacgg tgaagtagcc cagcagcacc acgaccgtga tcaccacggc caggcgcggc 4801 gccagatcgt cgtggtcgcg cggcggcttt ttcccggcat cgtcgggcaa gaggctcccc 4861 tgcactcgtc ctccggatgg tcgggccgga ttgggcggct tgcccgagag tatccgatct 4921 tttgcggggg aggagagggt gcggagaagg ctcatggcgt acacagagtt acgggttgtc 4981 accggggatc acaggaagaa tcacaggaaa aggggaacgg ggttcaggtc gcggtacgcg 5041 gtcggccgcc gcagccgccc cagggccacc gggacgtcgt acagccgccc gggggcgaac 5101 cggggccagt gcgggcgcag tccgggcacc agcaccttgg ccacgggcag ccccacatcc 5161 ggccgggtct ggtccagcac cagcagctcc atcccgcgcg cacggaccgc ctcccgtacg 5221 gcggccaggg cgtcgccgtc cgggggagcg gccatcccgg gcggcggcac cgcatccgga 5281 tcgggcgtca gatagggccc gttggcggtc gtcgcggtgc ggaaccagcg cagcgcctcc 5341 gcgtcggccg cgccgtatcc gccgccgtcg gcgcgggcct cgaccaccgc gggcagcatc 5401 tggttcagct cggcgaaggc gtggcacagc gcggcgtgcc ggtcgaagtg ggcgccgaat 5461 cccagcgtga tgtcctcggc gggcttgtcg gtacggcggg agagcgcggc gaccaccggg 5521 atgccgaagt cggtggtgag gtccagcgcc cacacctcgc gccgcagtcc gccgtgggcg 5581 cggcgcagtt cggccagcca cgggtcgtcg aaggcgtcaa gggggagcgc gggctgacgg 5641 gtgcggttgt accaccacag ggcgaccgcg tcccgctcga ccagctcaag gaagccccgt 5701 acgacggcgt cggcgagcgt ggacccggcc gccgcgccgt tggagtccgc ccggcagcag 5761 cgccgccccg ggggctgcgg ggcgccgtag tacagcagcg cggtgggcag cagccggtgc 5821 cgctcggcgg tgagcgacca cactggcgtc cagtccagct cggcgtcctc gtcgaacgga 5881 tcggggagcc ggtggcgcgg cgccctctgg tccggatacg gccgtgccaa ctgccgtgga 5941 tccacgagct ggacggtgtc cggatgcacc gcgtccgccg gatccagcgc gcggtagcgg 6001 gcgcgctggc gcggctcgtc gccctggaag tggccgctgt agtgctcgag ggcctcgcac 6061 agggcgctcg cccgggcctg ctcggcggtc cgccccttgc cgtgcgcggc ggcccccagc 6121 ccggcgcgta cggcgtccag cccgcccgga gaggtggcgt acgcggcgta cgaagggtgc 6181 cgggcgtggt agcagttgag gaacgccggg ccgcgcggat cgcggcggat ctcggtaacc 6241 agcccggtga cggggtccac cagatggccg taacgctcca tgacgcggcg cggtgaggcg 6301 tcgtcggtgg cgtctacgtg gttttcatgg ggctcgcgcg gcgacggcac ggccagcggc 6361 gcccgtatcc gctccgcgac cagcgccgga ttcccgcatc cggggcactg cgggcggcgg 6421 gcgagcggat ggcggtccac ggtggcggtg aggctgtcca gggtgcacag cgcctgctgg 6481 cccggatgcc ggtgcccggc cagccacttg gcggcctcca gcgcggccag ctggagcgcg 6541 gccgcgcggc tcgcgggcag tgaggcgggc ggccgcggca ccggccccgg gcggcccagc 6601 ctgcgctgga ggtacgcctc ggcctgccgc ccccgccaca gccggtcggc cagacacgcc 6661 cagcacgggt cctcgggggc gccgaggaac gggccgagcc acgcccgggt gcccaccggt 6721 ttgacgggca gccagcggcg gcccgcggcg cgatgggcgg cgtcgaccgc ggcgagccgc 6781 ggatcgagat agtcgtcgca caccacaagg gtgagttctg cggcgccgtg ttgacggggg 6841 ccgacttgac gtacggccca tcggcactcc cggccctgcg cggccggggc cgccgcccgg 6901 tcgtccccgg ctccctccgc gtctgccggg cccgccgccc gcagccccgc cgcccgcagc 6961 gcccggagga cttcggcagg gtcggccgac ccgaggatca ccgacgccac tgaggcggct 7021 gccgggcgtg ccgccgggcg tatggagcgc ccgtccccgc cgcccagact ggccagctcc 7081 cagtacgcct cctcgggccc gggagcgtgc gtgggctccc gctcggacac cagccccgcg 7141 gcccgcagcc gcgcgatgac ccgctccgcc tgcccggcgg gcaccgcgcc cggcagaccg 7201 gccgcgcggg cggcctcggt gaggatgtgc gcgaggtccc gcgacccgtc cagcagcggc 7261 gcgagcgccg cgatcgcccg cccgtgcagc gcggtgacgc cgtgctcgga gaccaggtag 7321 acggcctcgc ccggcaccgg ttcgacccgc agatgcgggg tgaagcccag ttcgcccgtc 7381 atgcgtccgc gtccctcatt ccccgccgaa cgtgcagatg cagatgcgtg gcgcgacggc 7441 cggccaggag gcgccggtca gatcctcgat gaccaggtcg tccagatcgt gcagatcatc 7501 cagagcgtcc agggcattcg gatccggatc ggggtccggc gcggccggga caccgccgtc 7561 ggccgcgggt tgcgggggga tggaggcttc cgtcatcaca ggctctcctc ggggtgggag 7621 gcggtcgtgg cccgggggcc gcggcggggc cgccgccgcg gttcagcgcc gccgtcatcg 7681 ccagggtgtg aatttgtcat gggtcgacct cccaggactc ataccgagtt cggtattccg 7741 gcactggtcg gaggcaccgc tcacccgcga gtcttttgtg tgcctcgatg gcacggccgc 7801 gcggccagga ggcacctgac ggaccgttga cggaggtaca ggaccatgga catcaaggtg 7861 ttggggccgc tgagcgtcga ggcgtgcggt cagtcgatcg tgcccagcgc gggcaagccg 7921 cggcagatcc ttgcactgct ttccgtctac gccaaccaga tgctgccggt gcccactctt 7981 atggaggaaa tctggggcac gcagatgccg cgcagcgcac ccaccacctt gcagacgtac 8041 atccttcagc tccgccgcag gctggccgcc gcttacggcc cccaggcacc gcaggcgtcg 8101 aaggatgtgc tggccacccg gtacggcggc tatgtcctgg aggcgcagcc gggcgcggtc 8161 gacatccatg agtacgaccg cctggtggcc gcggggcgtg acgcgctcga cgccggggac 8221 gatgtcgagg cgtccctgct gctgcgcgag gcgctcgcgg tctggcgcgg tccggcgctg 8281 gtggacgtgc gggtcggtcc ggtcctggag atcgagctgg cccggctgga ggagagccgt 8341 ctcggcgtcc tggagcgccg catcgaggcc gatctgcggc tcggccgcca tgccgagctg 8401 ctgaccgagc tgaccgagtt gaccgcccgt catccgctgc acgaggggct gcacgcccag 8461 tgcatggccg cgctgtaccg ggcgggccgc ccgtggcagg cgctggaggt ctaccagggg 8521 ctgcgcgccc ggctcgttga ggacctgggg ctcgagccct cgccgcggct ccagaagctc 8581 cagcaggcgg tgctcgcctc cgaccccgcg ctcgacctcg acctcgaagg gcactggcgc 8641 cgcccggtgc tcgacctgtt cgccgcctga cccgccgatc cgtacggtcc gttccgcgcc 8701 ccgccccgct tgaccgctcc acccgccgca caggccccgt cacctcccca gggcccgccc 8761 ggtgaccctc cccccgaacg cccggcgccg cccttcagcc gggtctgcta cggctccgct 8821 gcccgatccc cccgcgcggg caagcggagc cgtagtgcat ttcccgccca acgcccgcct 8881 gacctcgccg atccggatcc gatccggatc cgatccgatc cgacccgacc cgacaccgac 8941 ccgacaccga cccgatccga cctcccaccg acctcccgcc gaccgctcgt ccgacaccag 9001 ccgagggggc gccttgcgca tcgtcgacct gtccacaccg gtggacgccc ccgtgccctg 9061 cggcgcctcc ggcgcgcgcg ggatgtcgcg cgtcatcgac cggatgccga tggagtggtt 9121 cctgcgcccg gcgcacgtcc tggacatcac cggcgccgac ccggacaccc gcaccgccgg 9181 ggtcgaggac atcgagaagg cgctcgcccg gaccggctgc cgaccccgcc cgctggacgt 9241 cgtcctgctg cacaccggcg ccgcctgctg ggccggtacg ccgcgctact tcaccgactt 9301 caccggcctc gacggccccg ccaccgacta cctcctcgac ctgggggtcc gggtgatcgg 9361 caccgacgcg ttcagcctcg acgcgccctt ccacgacatg atccgccgct accacgccac 9421 cggcgaccgg tcggcgctgt ggcccgcgca cttcgcgggc cgccgccggg agtactgcca 9481 gatcgagcgg ctggcgcggc tggacaccct gccgtccacc gggttccggg tcgcctgctt 9541 ccccgtgaag accgcgggtg cgggcgcggg ctggacccgc gcggtggccc tgctcgacga 9601 ggtgtgagtc cggtggcgac ggcgcaccag gagatcgata ccgaggtctg tgtggtcggc 9661 ggcggcccgg ccggtctcgt gctggcgttg ctgatgctgc gctcgggggc gcgggtgacg 9721 gtgctggagc gctcccgcgc gcacgagcgg gagacccgcg gcgagatcct ccagcccggc 9781 gcgcaggcgc tgctggacga gctgggggtg ctcgccgggg cgcgggcgcg cggtgcccag 9841 gagcacgacc ggttccggct gttcgagggc gaccggatgc tgctggaggc cgactaccgg 9901 ctcctccccg ccccgtacga ccatctgctg tccctccccc ggacacatct gctggacgaa 9961 ctcctcgccc actgccgccg ctcgcccggc ttccgctatc tgcccggccg gagggtcggc 10021 ggcctggtgt ggcgggacgg gcggatcgcc ggggtcaccg ccgacgggcc ggacggccgc 10081 tgcaccgtgc gggcccgggc cgtggtcggt gcggacggcc gctactcccg cgtccggcgg 10141 ctggccggaa tcggcgcggg ccgcaccgag gcgcttcacc atgtgctgct gtggtgcacc 10201 ctcagggcgg gcggcgcgga cgccccgccg ctccgcgacg tgcgggtgtt ccgcaccggg 10261 gacggcccgg tggtggtcta cggctcctgg ccggaccgca tacacctcgg ctggacgctg 10321 ccgcagcacg gccaccgcgc cctcaccgcg ctcggcccgg accgggtcag ggagcggctc 10381 gcgcgcgccg tgccgccgta cgccacggcc atccgcgaac agatccgcgc cctgggcgac 10441 ctcgggctga tggacgtctt ctcggcccgc gcccggcgct gggtggacga cgggctggtg 10501 ctgatcggcg acgccgccca cacccacggc ccgatcgccg cccagggcat cacccttgcc 10561 atccaggacg cggtggtgct gcaccccgtg ctggccggtg cgctggccgc gggcgacgtc 10621 ggtgcggatc gcctcgccgc cttcgagggg cgccgggggc ccgatgtcgc ggccgtcgta 10681 cggatgcaga cccggcagag ccgggccctg ctctcgggcg gcgcgttcgc cactcgtgtg 10741 cgcccctacc tcgcccgggc gctgcgtcac accccactgc accgcaggat gctccaacgc 10801 atcgcgtacg ggggcccggc gatccgcgtc atggacgcca gggcgtgcgg gcgtccctga 10861 gcgggcggcg gcgcggcggc ccggtccggg gcggccccgg cgccgggtcg aggcgggctc 10921 aagtcacggc ggcgaccatg gcgttctcac aagaacgcca tccgggtacg accgcgagga 10981 gggggccgat ggtgccgagg gtgtcagatg cagcggggct gtccgtcgtg gtgctcggcg 11041 gcaccggcgc cctgggcggt gcggtccagc gcgcgttcga ggccgcgggc gcccgggtgc 11101 tggtgatctc ccgccgggag ccggagcccg gtgaggccgt ctcctgggcc gggctggatc 11161 tgaccagcgc cccgtccggg cagctcgccg ccctcctcgc cggggccgcc gccgacgtcg 11221 tggtgaacgc ggccgggctc acccgcggcg gcaccgagga gcagttggcc gctgccaacg 11281 ccgggctggt gcgcaccctg gtggaggccg ccgctgcgct gccgtaccgg ccgcggctgg 11341 tgcagctggg caccgtcgac gagtacggcc cggtgtgccg cggcgtcggc atcaccgagg 11401 atctgccgcc cgcaccggtc agcgcgtacg gccgcaccaa gctgctcggc gcgcaagccc 11461 tgctgggcgc cacccggtcc ggtgcggtgg acggcacggt gctgcggatc gcccatgtct 11521 tcggccccgg cgcgccccgc accgacctcc tgggcaccgc ggcccgtcat ctggcctccc 11581 actgccccgg tccgctgcgg ctggaaccgc tggaggggcg ctgggacttc gtggacgtca 11641 gggatgtcgc cgccgcggcc ctcgcggcgg cgacggcgcc ccgggcgagc ggacaggtcg 11701 tcaacatcgg ctgtggtcag gcgctgagcg tgcgccggct ggtggagcgc atgatcgtgc 11761 tcagcgggct cggcgtgccg ctggtggagg agccgggcgc cggcggtcat cccgcgggcc 11821 ccgcctggca gcgggtggac atctcccggg cccggctgct gctcggctgg cggccgcggt 11881 tcggcacggt ccggtcgctg cgcgaccagc tggccaaagc cggggcgccg aaccgcgcga 11941 tggtggcgcg cccaagatgg acctcgggcc tggacgggcg cacggccctg gtcaccgggg 12001 ccaccggcct cgtcggcgag ccgccgcccg cgccttctcg gcaaaagaat acggatgggc 12061 tggctttcag gaaccccggg aggccggtaa aggagattag cggggatctg gagggcccga 12121 cggataccaa gtcttccgat ggcagccgaa ttggaagatt ccacgcgccg ctctgggtcg 12181 tggccgccgt cgaggagcgc tggggcgcgc tcgacgtcct ggtggcgaac gcatggcggc 12241 ggggcgcgcg atgcgatccg cgcgcccgtt tcgaggacat ccccgagggt gactggctgc 12301 cggtcgtcgc ggacagcctc gccccggtga tccgtacggt gcagcgcgcc gtcgtcggga 12361 tgcgagagcg cggctggggc cg //