LOCUS NZ_GG657754 21086 bp DNA linear CON 01-MAY-2024 DEFINITION Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome shotgun sequence. ACCESSION NZ_GG657754 VERSION NZ_GG657754.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces himastatinicus ATCC 53653 ORGANISM Streptomyces himastatinicus ATCC 53653 Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group. REFERENCE 1 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D., Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Annotation of Streptomyces hygroscopicus strain ATCC 53653 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA REFERENCE 3 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Arachne v. April 2007 Genome Coverage :: 6x Sequencing Technology :: ABI ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_000158915.1-RS_2024_05_01 Annotation Date :: 05/01/2024 03:02:38 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.7 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 9,680 CDSs (total) :: 9,608 Genes (coding) :: 8,720 CDSs (with protein) :: 8,720 Genes (RNA) :: 72 rRNAs :: 4, 1 (5S, 16S) complete rRNAs :: 4, 1 (5S, 16S) tRNAs :: 64 ncRNAs :: 3 Pseudo Genes (total) :: 888 CDSs (without protein) :: 888 Pseudo Genes (ambiguous residues) :: 0 of 888 Pseudo Genes (frameshifted) :: 423 of 888 Pseudo Genes (incomplete) :: 530 of 888 Pseudo Genes (internal stop) :: 36 of 888 Pseudo Genes (multiple problems) :: 97 of 888 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 20:01:42 NOTE :: This is a single region extracted from a larger record! Orig. start :: 1521334 Orig. end :: 1542420 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to GG657754.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation was added to the scaffolds in August 2010. FEATURES Location/Qualifiers region 1..21086 /candidate_cluster_numbers="1" /contig_edge="False" /product="terpene" /region_number="10" /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /tool="antismash" cand_cluster 1..21086 /candidate_cluster_number="1" /contig_edge="False" /detection_rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /kind="single" /product="terpene" /protoclusters="1" /tool="antismash" protocluster 1..21086 /aStool="rule-based-clusters" /category="terpene" /contig_edge="False" /core_location="[10000:11086](+)" /cutoff="20000" /detection_rule="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /neighbourhood="10000" /product="terpene" /protocluster_number="1" /tool="antismash" proto_core 10001..11086 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /neighbourhood="10000" /product="terpene" /protocluster_number="1" misc_feature complement(151..166) /note="TFBS match to RutR, Regulator of the pyrimidine and purine metabolism, confidence: weak, score: 20.26" /tool="antismash" misc_feature complement(385..397) /note="TFBS match to LuxO, Repressor of luminescence, confidence: weak, score: 19.4" /tool="antismash" misc_feature complement(413..425) /note="TFBS match to LuxO, Repressor of luminescence, confidence: weak, score: 17.42" /tool="antismash" gene 509..>1148 /locus_tag="SSOG_RS05755" /pseudo="" CDS 509..>1148 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010033044.1" /locus_tag="SSOG_RS05755" /note="incomplete; too short partial abutting assembly gap; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /product="aminoglycoside phosphotransferase family protein" /pseudo="" /transl_table=11 /translation="MYAASSSVSAPPRPYRRQLPGNGPYLDPAPGGRARRTAAVGSVPP SGRLDVSGPQGAQLRTAIAAVHRICPEFNPVQVLRRSGRSVLLVGSTGRTTAVAKCLLD HSPAWAERFRREIAMYRTFVRQRPPVRVPRLIAADPDNCALVIERMPGRVAAVQRHPAE APPRADVRAALGAICRINQWRPPGDLFDAPVDYAARLSRYHELGLLTDRD" gap 1149..1864 /estimated_length=716 gene 2189..3894 /locus_tag="SSOG_RS05760" /old_locus_tag="SSOG_01159" /pseudo="" CDS 2189..3894 /GO_function="GO:0042834 - peptidoglycan binding [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018569434.1" /locus_tag="SSOG_RS05760" /note="frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01159" /product="peptidoglycan recognition family protein" /pseudo="" /transl_table=11 /translation="MHLTDAFTALFSAPHHSQGTEDARGDLARPLKVPEASVPEPRQLP ARLRTLDRAAELTGLSAAELRGDAAANVRGGAALLAATQKRLGLPSSDDPADWYAAVAA YPGADSAAAAAVFADDVYDVIRGGAARTTGDGERVTLDAVPGVAPGTGGSCGRSACRPP SGIRTSRPPAMCPASGSRPPTSSSGTTTTATTTSATAPSPK" gene complement(3896..6223) /locus_tag="SSOG_RS05765" /old_locus_tag="SSOG_01160" CDS complement(3896..6223) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_004003908.1" /locus_tag="SSOG_RS05765" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01160" /product="glycoside hydrolase family 95 protein" /protein_id="WP_009713270.1" /transl_table=11 /translation="MARWTLWYDTPAADWEREALPIGNGTLGAMVFGGVARERIQFNEK SLWTGGPGGPGSAPYDSGNWREPRPGALAAVQRLIDEHGAAAPEDVAARLGQPRSRYGA YQPFGDLWLEIPGAPESPDSYRRLLEIRKGVALVKYTAQGVRHRREFFASYPDRVIVGR FDAAPGTVGFTLRHTSPRPGDHHVTAHDGRLTIRGALEDNGLRFEAQVRVMADGGTVTS GEDGTLTVTGAHSAWFVLAAGTDYADTHPHYRGEDPHRTVTGTVDAAADRGYLTLLSRH VRDHRALFDRTALDLGGRTPPRTPTDRQRAAYTGGESPADRALEELFFDYGRYLLIASS RPGAPLPANLQGIWNDSVRPAWSADYHTNINLQMAYWPAHALHLAETAEPLHRFITALR APGRITAREMFGARGWVVHNETNAYGFTGVHDWSTAFWFPEAAAWLVHHLYEHYRFTLD TGFLRDTAYPAMREAAAFWLDTLRPDPRDGTLVVSPGYSPEHGDFTAGPAMSQQIVHDL LTATLEAARTLGDDPALQAGLRRALDALDPGLRIGSWGQLQEWKADLDDPADTHRHASH LFALHPGRQIAPDGPWAGAAAVSLDARGDGGTGWSRAWKVNFWARLRDGDRAHRLLAGQ LTDSTLPNLWDTHPPFQIDGNFGAAAGIAQMLLQSHRAVLDVLPALPRRWPDGAVRGLR AHGDLTVDITWREGRARTLTVAAGHDGPVRIRSDLFARPYTAHDDTTGRETAVRDDPGS GDACTVTLAARGGRTYRFTARD" misc_feature complement(6083..6085) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene complement(6236..6736) /locus_tag="SSOG_RS05770" /old_locus_tag="SSOG_01161" CDS complement(6236..6736) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018550733.1" /locus_tag="SSOG_RS05770" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01161" /product="hypothetical protein" /protein_id="WP_009713271.1" /transl_table=11 /translation="MSFLRRRSAATPTGPDFDVLAMDPGDWPGDLGAGLLPAPDGTCQG VFLRYDLFGGRGPAMIIGNLPEGSPAREVAEGQAPFEVTQLLAALGNEEQVQVVDTEDT PVMHDDNLLIVRRIKLSEGRISCAQFDRSDGVLVTIASWDRPITDDLYRLLKPLPAEMF QQG" gap 6978..7154 /estimated_length=177 gene complement(<7155..9100) /locus_tag="SSOG_RS05775" /old_locus_tag="SSOG_01162" /pseudo="" CDS complement(<7155..9100) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="SSOG_RS05775" /note="incomplete; too short partial abutting assembly gap; missing C-terminus; Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="SSOG_01162" /product="ATP-binding protein" /pseudo="" /transl_table=11 /translation="MLDTAHPPGSQIVRDVLARADERLPRVLGVTGGNPFEVVELTAKV RDRDLKPQTVNLGALRELVAAAKDSGLGDRLTRLGTAAVRLAWAVAVLGIEATPSLTAN VAGLSETETAEQVARLADARILAPPRQSARGAQPLEFLHPLIATAVYQAIPGALRVAMH GQAATVVLAAGLGSAAAGRHLLEMHPEGDSWVVRHLREAAREYLRAGAPDAGRRCLARA LREPPAPEERAAVLYELGCSAQLTEPAVTVNHLRAALEEPDLGSDLREAITYRLAQAYG HSGRMEEAAQVVAAEVPRATSARTRLRMQAEQFMWSMFRADEKESPARSRRLARLADHL TGRGMAERYLLGLRAWDAMTRGEPAATALHYAEEALGSGLSWTDDDWGFEVPILVALIF LHCDQPGRAEALFNTGIAECERKGWRGSHLAFGITLLGYARLRRGALVEAEELAREGMR IADLVGSSTPAHWTAVGTLIETLISRGRIREAQEFAAGHGGEILPQAVLCPDVPTVRGE LLLASNLHGEARQQLADVGRRMDGRGMRNPVWCPWQLHMAQALALTDPNQAAEVADDAV RRARQFGTHSAIGRALHSAAAVAQGSERIKLLAEAVSHLERSPSAYDLAVALVDHGAAL RTRRPAPGGRGPA" gene complement(9159..9752) /locus_tag="SSOG_RS55670" CDS complement(9159..9752) /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: protein motif:HMM:NF024589.4" /locus_tag="SSOG_RS55670" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="ATP-binding protein" /protein_id="WP_245606576.1" /transl_table=11 /translation="MRDRQDRTRRALLEREAELAAVDHALTDLCGSDPGDPSGTRTGGV IAFAGPGGLGKTALLGEMRRRAAHRGCTVMSARGGEHEQGAAFHVVRQLFQPVLATTGE EEHRRILGSWYDIVAPAVGLVVSGSGGAPDPQGVRDGLDWLVTRFAVEHAPVVMILDDV HWADPESLDWLLRVRRPRRGTCPCCSPSATARKT" misc_feature 9815..9832 /note="TFBS match to HipB, Bacterial antitoxin HipB, confidence: weak, score: 20.89" /tool="antismash" gene 10001..11086 /locus_tag="SSOG_RS05780" /old_locus_tag="SSOG_01163" CDS 10001..11086 /EC_number="4.2.3.157" /GO_function="GO:0016829 - lyase activity [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) terpene: T1TS" /gene_functions="biosynthetic-additional (smcogs) SMCOG1052: Terpene synthase/cyclase metal-binding domain protein" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014058745.1" /locus_tag="SSOG_RS05780" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01163" /product="isoafricanol synthase" /protein_id="WP_009713273.1" /sec_met_domain="T1TS (E-value: 6.2e-73, bitscore: 245.7, seeds: 237, tool: rule-based-clusters)" /transl_table=11 /translation="MNATYTTTSRPHARHAALLSRAALLDIPASADPSPGTGAARVHTV QWLSRYGVFRAGGAVAEYDALRFDLLNGLFYPRTTGAELDVGNDLIGWYFVFDDQFDGE LGCRPEAVARMVRDVIRVTEEPDDAPGQGGGPLLESFRDLWRRIHAGRPPVWRERFRHH WLEYLHSYHREALDRSGTQGPPLSVDAVLALRRHSIGVQPCLDLNERFGGYALPAALHG GHPLARMREATDDVVVFTNDIASLDKELAAGDLHNTVIVRHQCHGGTLEDAVEHIAGLA NARYRWFEQTADRLPRLLADAGAGTDLRRDVDHYVDGMRDVMCGNLGWSLRTARYDERG IAAVSDGRQRPWAGLSAPGSG" gene 11146..11874 /locus_tag="SSOG_RS48200" /old_locus_tag="SSOG_01164" CDS 11146..11874 /GO_function="GO:0005515 - protein binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014173683.1" /locus_tag="SSOG_RS48200" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01164" /product="leucine-rich repeat domain-containing protein" /protein_id="WP_039940678.1" /transl_table=11 /translation="MNDTLNLWKAGLAEAPDAIWQHTGLRVLILADNALTRLPPALGRL LRLHTLDLGHNRLAGIPEEIGELSGLTRCLYLHDNRLPRLPRSLGRLDRLGYLNVGENP LGGLPEELGGMAGLVELRAQHAELTALPGSIGQLSALRELWLRGNRITALPAGVSALRA LRQLELRENALSEVPEPLRGLPRLRHLDLRGNRIRTLPDWVAELPALEKLDLRWNPLDE GVDDGPVVRALGERGCVVLG" gene complement(11944..12189) /locus_tag="SSOG_RS05790" /old_locus_tag="SSOG_01165" CDS complement(11944..12189) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009713275.1" /locus_tag="SSOG_RS05790" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01165" /product="DUF397 domain-containing protein" /protein_id="WP_009713275.1" /transl_table=11 /translation="MADTTTTAQPLRGNGEKPDLDLTSAQWQSSSQGVGDVEIAFVEGF IAMRHGRRPEGPALIFTPAEWRAFVLGAREGEFDLT" gene complement(12305..13471) /locus_tag="SSOG_RS05795" /old_locus_tag="SSOG_01166" CDS complement(12305..13471) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019057880.1" /locus_tag="SSOG_RS05795" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01166" /product="thiolase domain-containing protein" /protein_id="WP_009713276.1" /transl_table=11 /translation="MSKEPVAVVGIGQTKHTAARRDVSIAGLVREAAVRALEDAELTWA DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPPAIGA LVAYKDRRNALLNPYAHLHEQDLTLEKVQSSPMLWDPIRYSETCPSSDGACAMVLTDRT GASRAPRPPAWMHGGAMRSEPTLFAGKDCVSPRAGRDCAADVYRQAGITDPRREIDAIE MYVPFSWYEPMWLENLGFAAEGEGWKLTESGVTEIGGDLPVNPSGGVLSTNPIGASGML RFAEAALQVRGRAGEHQVEGVRTALGHAYGGGSQFFAMWVVGAAPPST" gene complement(13480..14541) /locus_tag="SSOG_RS05800" /old_locus_tag="SSOG_01167" CDS complement(13480..14541) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016433333.1" /locus_tag="SSOG_RS05800" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01167" /product="thiolase domain-containing protein" /protein_id="WP_009713277.1" /transl_table=11 /translation="MRDVAIVAFGQSGTRRTSAEVSEVEMLMPVLHQVLGAVGLRAGEI DFTCSGSSDYLAGRAFSFTMALDGVGAWPPIAESHVEMDGAWALYEAWVKLLTGEADTA LVYSYGKSSPGDLPEVLTRQLDPYYVAPLWPDSVSLAALQAQALIDAGDTDERALAEVA ARGRNAAADNRHAQVTRSAPPGALLDAPYLVRPLRRHDCPPIGDGAAAVVLAAGDTARR LCARPAWIRGMDHRIEPHGLGVRDLTRSPSTRLAATRAGAFEAPVDLAELHAPFTSQEI ILRRELELDDGVRLNPSGGAPAANPMMAAGLIRLGEAAAALHRGDADRALAHATSGPCL QQNLVAVLEGEAR" gene complement(14542..15501) /locus_tag="SSOG_RS05805" /old_locus_tag="SSOG_01168" CDS complement(14542..15501) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014058750.1" /locus_tag="SSOG_RS05805" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01168" /product="OB-fold domain-containing protein" /protein_id="WP_039936668.1" /transl_table=11 /translation="MTPAPAPEVLKAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRT AGGRVLVPPVEYDPDTAAELRDLVEVAPTGTVTTWAWNPAPRRGQPLSTPFAWALVRLD GADTALLHALDAPGPDAVRTGMRVRVRWAEEREGSITDIACFEPYDGPATHEPGPHDGV FADPVTGIVAPARLDYTYAPGRAQSRYLAALAGRKTVGERCPSCRKVYVPPRGACPTCG VATEEQVEVGPGGTVTTFCIVNIKARNLDIEVPYVYAHIALDGADLALHGRIGGIPYDQ VRMGLRVTPVWTEGGRYPDHYRPTGEPDADYDTYKELL" gene complement(15532..16338) /locus_tag="SSOG_RS05810" /old_locus_tag="SSOG_01169" CDS complement(15532..16338) /NRPS_PKS="Domain: ECH (15-260). E-value: 1.6e-50. Score: 163.6. Matches aSDomain: nrpspksdomains_SSOG_RS05810_ECH.1" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1023: enoyl-CoA hydratase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014173688.1" /locus_tag="SSOG_RS05810" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01169" /product="crotonase/enoyl-CoA hydratase family protein" /protein_id="WP_009713279.1" /transl_table=11 /translation="MPHGTEHLIVERIGATLVLTLNRPEAKNALSLPMLVGLYDGWIEA DEDDTVRSVVLTGAGGVFCAGMDLKALAGGGRMEGQHYRDRLKADPDLHWKAMLRHHRP RKPVIAAVEGHCVAGGTEILQGTDIRVAGRGATFGLYEVRRGLFPIGGSTVRLARQVPR THALEMLLTGRPYAAGEAERIGLIGQVVDDGTALKKALEIAELINANGPLAVEAVKASV YETAEMTETDGLASELERGWPIFDTADAKEGSKAFAEKRPPVYRRA" aSDomain complement(15559..16293) /aSDomain="ECH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS05810_ECH.1" /evalue="1.60E-50" /label="SSOG_RS05810_ECH.1" /locus_tag="SSOG_RS05810" /protein_end="260" /protein_start="15" /score="163.6" /tool="antismash" /translation="TLVLTLNRPEAKNALSLPMLVGLYDGWIEADEDDTVRSVVLTGAG GVFCAGMDLKALAGGGRMEGQHYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGHCVAG GTEILQGTDIRVAGRGATFGLYEVRRGLFPIGGSTVRLARQVPRTHALEMLLTGRPYAA GEAERIGLIGQVVDDGTALKKALEIAELINANGPLAVEAVKASVYETAEMTETDGLASE LERGWPIFDTADAKEGSKAFAEK" gene 16503..18119 /locus_tag="SSOG_RS05815" /old_locus_tag="SSOG_01170" CDS 16503..18119 /NRPS_PKS="Domain: AMP-binding (8-435). E-value: 3.1e-72. Score: 235.3. Matches aSDomain: nrpspksdomains_SSOG_RS05815_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007458480.1" /locus_tag="SSOG_RS05815" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01170" /product="acyl-CoA synthetase" /protein_id="WP_009713280.1" /sec_met_domain="AMP-binding (E-value: 9.4e-73, bitscore: 244.2, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MEYNLADLFESIVDTVPDREALVYADHPGTGAERRLSYAQLDAAA NRLAHHLRNSGVAPGEHVGLHLFNGVEYLQTVLACLKIRAVPVNVNYRYVEDELVYLYR DADLTALVYDAEFGDRVAAALPRTDTLRHLVQVGAGEGAPGAVPFAEAEASGAAGRGFA PRSADDRFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGVPVGRPEELAERVAASGD GLVFFPTAPLMHGTSTLTTFIGLNFGQKVVLHRKFVPEEVLRTIEKEKVSTVSLVGDAM LRPLVDALTGPLKDIDLSPLLSVSSSGAILSDTVRAQFAALAPHTLMLNNFGSSESGFN GTATEDSGPERGFRVRVNDRTAVVDPATHRPVAPGEPGRVAQRGHVPLGYYNDPKKTAE TFFEADGERWVLLGDMATVDEDGVITVLGRGSQCINTGGEKVYPEEVEQALKAHPDVYD ALVAGVPDERWGNRVAAVVQPREGADALTADAVRDHCRTRLAGYKIPRTVVFTDRIQRS PSGKADYRWARTVAAGDGTGA" aSDomain 16527..17807 /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS05815_AMP-binding.1" /evalue="3.10E-72" /label="SSOG_RS05815_AMP-binding.1" /locus_tag="SSOG_RS05815" /protein_end="435" /protein_start="8" /score="235.3" /specificity="substrate consensus: X" /tool="antismash" /translation="FESIVDTVPDREALVYADHPGTGAERRLSYAQLDAAANRLAHHLR NSGVAPGEHVGLHLFNGVEYLQTVLACLKIRAVPVNVNYRYVEDELVYLYRDADLTALV YDAEFGDRVAAALPRTDTLRHLVQVGAGEGAPGAVPFAEAEASGAAGRGFAPRSADDRF IIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGVPVGRPEELAERVAASGDGLVFFPTA PLMHGTSTLTTFIGLNFGQKVVLHRKFVPEEVLRTIEKEKVSTVSLVGDAMLRPLVDAL TGPLKDIDLSPLLSVSSSGAILSDTVRAQFAALAPHTLMLNNFGSSESGFNGTATEDSG PERGFRVRVNDRTAVVDPATHRPVAPGEPGRVAQRGHVPLGYYNDPKKTAETFFEADGE RWVLLGDMATVDEDGVITVLGRGSQCIN" CDS_motif 17013..17063 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS05815_0001" /evalue="3.00E-06" /label="NRPS-A_a3" /locus_tag="SSOG_RS05815" /protein_end="187" /protein_start="170" /score="19.8" /tool="antismash" /translation="FIIYTGGTTGMPKGVMW" CDS_motif 17658..17705 /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS05815_0002" /evalue="2.60E-04" /label="NRPS-A_a6" /locus_tag="SSOG_RS05815" /protein_end="401" /protein_start="385" /score="13.4" /tool="antismash" /translation="VPLGYYNDPKKTAETF" gene complement(18132..18959) /locus_tag="SSOG_RS05820" /old_locus_tag="SSOG_01171" CDS complement(18132..18959) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014174065.1" /locus_tag="SSOG_RS05820" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01171" /product="hydrolase" /protein_id="WP_039936669.1" /transl_table=11 /translation="MTPRIKTTKAFYRTGATTFFASQHDQRFSYSLHVPSVHETTTTPL PLLVIQHGTGRTAAEYRNAMAEFSERHGVVILTPLFPAAIGDPDDLHNFKFIEYDGIRY DRELLAIVDEVGTRFTVDTDRFMLQGFSGGGQFAHRFLYLHPERLCAVSIGAPGRVTLI DPDREWWLGTAGFEERFGAPVRLEEIRKVAVHMVVGAEDTETWEINNPGDSNWMDGADA LGRTRVERITALRDNYVALGIDVTLDIVPGVGHSGTGVLDAVRDFAARVLTTR" gene complement(19073..20146) /locus_tag="SSOG_RS05825" /old_locus_tag="SSOG_01172" CDS complement(19073..20146) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014174066.1" /locus_tag="SSOG_RS05825" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01172" /product="DUF5937 family protein" /protein_id="WP_009713282.1" /transl_table=11 /translation="MPVVIDLGPAPEERIAGRLSPLAELCACLHALDEPRHHPASRRWV GAVLQGADERLLARAAQWAPLWGAFRARYLLPLTPGPERSLEEELADIGELPEATFTAM TEQALIGQNSHQPTGVPGNTPERFLGRLRQMSDGRFALGVRLLAGPAAFREDLTDFLHA AADELFEGEWARLRRALEADVRMRFQKHRLDGARALADFPTARVEDDPPRVVFDKLYNG RASLADVPCLLVPSRHINPHVAIKHYPGYPVVVQYPVRGDGDGEPPAMDEVLRRVRALD EPLRVRVCRVLLRQSMTTTELASHFDTTPPQMSRHLRKLREAGMVHTHRQGARVHYQLD EEAVRTLGVDLLSALRR" misc_feature 21003..21022 /note="TFBS match to DosR, Hypoxia stress response regulator, confidence: medium, score: 23.92" /tool="antismash" ORIGIN 1 cggtgaagag gacggccagc accttgggca cgggatcgcg cggcgtctcg ccggtgtcga 61 tccaacgccg cacccgcgag gtgtcggttg ccagctgcgg gtggcccatg gccgccgcgc 121 gccggttcac gagcctcgcg agctcgccct tggaccagcc ggccaggccg aaaaggtccg 181 caagacgggt gttgggttcc ctcgtcacgt caagccccca ggatcctcgg ctgacttgac 241 agtaacgggc ccgtcacgag ccgtgcgact attcgccagg gttcgccagg gtccgccaga 301 tggtgtgcca cccgcgcgcg ggtgtgatgt aggagtgcgc tacccggccc ggtgcgggtt 361 ggaaaatccg cttggaaaat ccagttggaa aatgccagcg ggaaaccgcc cgttggaaaa 421 cgccagccgc attccccagg gtgcggcccc gccccggggc cgggagcgta cgtacatacg 481 tcggcacacg aagggatctg tctcgcccat gtacgcagcg tcgtcctccg tgtccgcccc 541 acctcggccg taccggcggc agctgcccgg caatgggccg tacctcgatc ccgctcccgg 601 cggccgcgca cggcgcaccg ccgccgtcgg ctccgtgccg cccagcggaa gactcgacgt 661 gtccggtccc cagggtgcgc agctgcgcac tgccatcgcc gcggtccatc gcatctgtcc 721 ggagttcaac ccggtccagg tgctccggcg cagcgggcgg tccgttctcc tggtcggttc 781 gacgggccgc accacggcgg tcgccaaatg cctgctggac cactccccgg cgtgggccga 841 gcggttccgc cgcgagatag cgatgtaccg gacgttcgta cgacagcgtc cacccgtccg 901 ggtgccgcgg ctgatcgccg ccgaccccga caactgcgcc ctggtcatcg agcggatgcc 961 cgggcgggtc gcggccgtgc agcgccatcc cgccgaggcg ccaccgcgcg ccgatgtgcg 1021 cgccgcgctc ggcgcgatct gccggatcaa ccagtggcgg ccgccggggg atctgttcga 1081 cgccccggtc gactatgccg cccggctctc ccgctaccac gagttggggc tgctgaccga 1141 ccgggacann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 1861 nnnngccccc gacaccacca gagacgcgga ccggaacggc gacagacccg tccccggccc 1921 cagccggagg acggcgctgc gcaccgcggg cgccgccgcg tccgccgcct ttctgctccc 1981 ggtcgtctcc gggaccccgg ccgcccgcgc cgatcagccg ccgggcggca caccgtcgcc 2041 ggaaggggcc ggggcgctgc aacgggcctt cgcggcggcg gcgaaggagc acggggtgcc 2101 gctgagcgtg ctgctgggcg tgtcgtatct ccagtcccgc tgggacggcc atcgtggcgc 2161 gcccagcgtc accggcggct acggcccgat gcacctcacc gacgccttca ccgccctctt 2221 ctcggccccg caccacagcc agggcaccga ggacgcccgc ggcgacctgg cgcggcccct 2281 caaggtgccg gaagcctccg taccggagcc gcggcagctg cccgcgcggc tgcgcacgct 2341 ggaccgggcc gcggagctga cggggctgtc cgccgccgag ctgcgcggcg acgcggcggc 2401 caatgtgcgc ggcggcgccg ccctgttggc ggccacgcag aagcggctgg ggctgccgtc 2461 gagcgacgat ccggcggact ggtacgcggc ggtggcggcc tacccgggcg ccgacagcgc 2521 cgcggcggcc gccgtgttcg ccgacgacgt ctacgacgtg atccgcggcg gcgccgcgcg 2581 caccacgggc gacggtgagc gggtcacgct cgacgccgtc cccggcgtcg cccccgggac 2641 cggcggcagc tgcggtcgct cggcctgccg tcccccaagc gggatccgca cgtcgaggcc 2701 cccggcaatg tgtcctgcga gtggatcccg gccccctacg agcagttcgg ggacaacgac 2761 tacggcaacc acgacctcgg caaccgcccc ctctcccaaa tgatcgacta catcgtcatc 2821 catgacaccg agggctcctg ggacaccacc atcaagctgg tccaggaccc gacgtatgtc 2881 tcctggcagt acacgctgcg ctcctccgac ggccatatcg cccagcacgt accgctcaag 2941 gacgtcgcct ggcacgcggg caactggtac gtcaacgcca agtccatcgg cctggagcac 3001 gagggctttc tgaccgcgcc cgacgcctgg tacacggagg cgatgtaccg ctcgtcggcc 3061 cggctggtga agtggctggc gcggcggtac ggcatcccgc tggaccggca gcacatcctg 3121 ggccacgaca atgtgcccgg cacgaccgcc accaccatca agggcatgca caccgacccg 3181 ggcccctact gggactgggc gcactacttc agcctcctcg gcgccccgtt ccaccgcacc 3241 gcgggcgcct ccggcgggct ggtcaccatc cgcccggact acgagacgaa cgaaccggtg 3301 tacaccggct gcgagacggc cggtcaggag tgcgccccgc acggttcgtc cgcggtgcgg 3361 ctgcacacgg cgccgagcga cgacgccccg ctggtcaagg acatcgggct gcgtccggac 3421 ggcgccgatt cgaccaccgg cgtcaacgac accggcgccc gcgccaccac cggccagcag 3481 tacgcgctcg cgggccgtca gggcgactgg acggcgatct ggtacctcgg ccagcaggcg 3541 tggttccgga acccgcggcg gcggcccacc gccgtgtacg gcaagggcct cgtcgtcacg 3601 ccgaagccgg gcctggcgga ggtcccggtg tacgggcgcg cctacccgga gaaggaggcg 3661 tacccggagg gcgtaccggt gcaggcggtc tcaccgctgc cgtacaagct gctcgccggg 3721 cagcggtacg cgctggggct gcggacccag ggcgagtatc tgtgggcgac cacgttcgat 3781 ggatccgggc acatcgtggt gcgcggtcag gacatctact accagatcca gttcgggcac 3841 cgggtggcgt tcgtccgggc cgcggatgta cgggtgcggc gctccggccg atgagtcagt 3901 cgcgggccgt gaagcggtag gtgcggccgc cgcgggccgc gagcgtgacc gtacaggcgt 3961 ccccggagcc ggggtcgtcg cgtacggccg tctcgcggcc cgtggtgtcg tcatgggcgg 4021 tgtacgggcg cgcgaacaga tcgctgcgta tccggaccgg cccgtcgtgt cccgccgcga 4081 cggtgagggt acgggcgcgc ccctctcgcc aggtgatgtc gaccgtgagg tcgccgtggg 4141 cgcgcagccc gcgcaccgcg ccgtccggcc agcggcgcgg cagggcgggc aggacgtcca 4201 gcacggcgcg gtggctctgg aggagcatct gggcgatccc ggcggcggcg ccgaagttgc 4261 cgtcgatctg gaacggcgga tgggtgtccc acaggttggg gagggtggaa tccgtcagct 4321 gtccggcgag cagccgatgg gcgcggtcgc cgtcgcgcag ccgggcccag aagttgacct 4381 tccacgcccg gctccagccg gtgccgccgt cgccgcgcgc gtccagggag accgcggcgg 4441 ccccggccca ggggccgtcc ggggcgatct gccgtccggg gtggagggcg aagaggtggg 4501 aggcgtgccg gtgggtgtcg gcggggtcgt ccagatcggc cttccactcc tggagctggc 4561 cccaggagcc gatgcgcagc cccgggtcga gggcgtccag ggcgcgccgc agcccggcct 4621 ggagggcggg gtcgtcgccg agggtgcggg ccgcctccag ggtggcggtg agcaggtcgt 4681 ggacgatctg ctgggacatg gcgggccccg cggtgaagtc gccgtgctcg ggcgagtagc 4741 cgggcgagac gacgagggtg ccgtcccggg ggtccgggcg cagcgtgtcc agccagaacg 4801 cggcggcctc ccgcatcgcc gggtacgcgg tgtcccgcag gaagccggtg tcgagggtga 4861 agcggtagtg ctcgtagagg tggtggacca gccaggcggc cgcctcgggg aaccagaagg 4921 cggtggacca gtcgtggacg ccggtgaagc cgtacgcatt ggtctcgttg tgcacgaccc 4981 agccgcgcgc gccgaacatc tcgcgggccg tgatccggcc gggggcgcgc agggcggtga 5041 tgaagcggtg caacggctcg gcggtctccg cgaggtgcag ggcgtgggcc ggccagtagg 5101 ccatctgaag gttgatgttg gtgtggtagt cggccgacca ggcgggcctg acgctgtcgt 5161 tccagatgcc ctggagattg gcggggagcg gggcgccggg gcgcgatgag gcgatgagga 5221 gatagcggcc gtagtcgaag aacagctcct ccagggcgcg gtcggccggg ctctcgccgc 5281 ccgtgtacgc ggcgcgttgc cggtcggtgg gcgtgcgggg cggggtccgg ccgccgagat 5341 ccagcgccgt acggtcgaac agggcgcggt ggtcgcggac atggcggctc agcagggtca 5401 gatagccacg gtccgcggcg gcgtccacgg tcccggtcac ggtccggtgg gggtcctcgc 5461 cgcggtagtg ggggtgggtg tcggcgtagt cggtcccggc cgcgaggacg aaccaggcgc 5521 tgtgggcgcc ggtgacggtg agtgtgccgt cctccccgga tgtcacggtg ccgccgtcgg 5581 ccatcacccg cacctgggcc tcgaagcgca gcccgttgtc ctccagcgcg ccgcggatcg 5641 tcaaccgccc gtcgtgcgcg gtgacgtggt ggtcgccggg gcggggtgag gtgtggcgca 5701 gggtgaagcc gaccgttccg ggggccgcgt cgaaccgtcc gacgatcacc cgatcggggt 5761 acgaggcgaa gaactcgcgc cggtgccgca cgccttgggc cgtgtacttc acgagggcca 5821 cgcccttgcg gatctccagg agtcgccgat agctgtccgg ggactcgggc gcacccggga 5881 tctccagcca cagatcgccg aagggctggt aggcgccgta gcgggagcgg ggctgtccga 5941 ggcgggccgc cacgtcctcg ggggcggccg caccgtgctc gtcgatcagc cgctggacgg 6001 cggcgagggc gcccgggcgc ggctcacgcc agttgccgga gtcgtacggc gcggatcccg 6061 gaccgccggg gcccccggtc cataacgact tctcgttgaa ctggatccgc tcccgggcca 6121 caccaccgaa gaccatggcg ccgagcgtgc cgttgccgat gggcagcgcc tcgcgctccc 6181 agtccgccgc gggggtgtcg taccagagcg tccagcgggc caccgggggt gtccctcagc 6241 cctgctggaa catctccgcg ggcagcggct tgagcagccg gtacaggtcg tcggtgatcg 6301 gccggtccca gctggcgatg gtgacgagga cgccgtcgct gcggtcgaac tgggcgcagg 6361 agatccggcc ttcggacagc ttgatccggc gcacgatgag gaggttgtcg tcgtgcatga 6421 ccggggtgtc ctcggtgtcc acgacctgga cctgctcctc gttgccgagt gcggccagca 6481 gctgggtcac ctcgaacgga gcctggccct cggccacctc acgggccggg gagccctcgg 6541 gcagattccc gatgatcatc gccgggccgc ggccgccgaa caggtcgtag cgcaggaaga 6601 cgccctgaca ggtgccgtcc ggcgcgggca gcagccccgc gcccagatcg ccgggccagt 6661 cccccgggtc catggccagg acatcgaagt ccggcccggt gggcgtggcg gcgctgcggc 6721 ggcggaggaa ggacatgcgg acatggtacg tggcccgcca ccgtccccct gctggggagc 6781 acccctcctc cggcccgccg tcacagcctc ttcacgggcc gccacacggc cccggcctcc 6841 ggctcagtcc cggctcagtc cccggggagc gggtgcgggg ggcggtcggg gcggggggtg 6901 cccagcaggg tggcgaggcc gccccggtcg gtgcccgcct tgcggtagac gccggacagc 6961 agccgggcca cctcgcgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 7081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 7141 nnnnnnnnnn nnnnagagcc ggtccccggc ctcctggggc aggccgacgc gtgcgcaggg 7201 cggcgccgtg gtcgaccagc gccacggcca ggtcgtacgc ggacggcgag cgctccagat 7261 ggctgacggc ctcggccagt agcttgatcc gctccgatcc ctgggccacg gcggcggcgc 7321 tgtgcagcgc ccggccgatc gcggagtggg tgccgaactg gcgggcgcgg cgcaccgcgt 7381 cgtcggcgac ctcggcggcc tggttcgggt cggtcagcgc gagggcctgg gccatgtgga 7441 gctgccaggg gcaccagacg gggttgcgca taccgcggcc gtccatccgg cggccgacgt 7501 cggcgagctg ctggcgggcc tcgccgtgca ggttggaggc gagcagcagt tcgccgcgga 7561 cggtgggcac gtcggggcag agcacggcct gcgggaggat ctcaccgccg tggccggccg 7621 cgaactcctg cgcctcccgg atccggccgc ggctgatcag ggtctcgatg agggtgccga 7681 cggcggtcca gtgcgcgggc gtcgaggagc ccacgaggtc ggcgatgcgc atgccctcgc 7741 gggccagctc ctccgcctcg acgagcgctc cgcggcgcag ccgggcgtat ccgaggaggg 7801 tgatcccgaa cgccaggtgg gagccgcgcc agcccttgcg ctcgcattcc gctatgccgg 7861 tgttgaacag cgcctcggcg cgtccgggct ggtcgcagtg gaggaagatc agggcgacca 7921 ggatcggcac ctcgaagccc cagtcgtcgt cggtccagct caggccggag cccagggcct 7981 cttccgcata gtgcagggcg gtggccgccg gttctccgcg cgtcatcgcg tcccaggcgc 8041 gcaggcccag cagatagcgc tcggccatgc cgcggccggt gaggtggtcg gcgagccggg 8101 cgaggcgccg ggagcgggcg ggggactcct tctcgtcggc gcggaacatg ctccacatga 8161 actgctcggc ctgcatgcgc agccgggtgc gggcgctggt ggcgcggggc acctcggccg 8221 cgacgacctg cgcggcctcc tccatgcggc cgctgtggcc gtacgcctgg gcgagccggt 8281 aggtgatcgc ctcgcgcagg tcggagccga ggtccggctc ctccagggcg gcccgcagat 8341 ggttgacggt gacggcgggc tcggtgagct gggcggagca gcccagctcg tacaggacgg 8401 cggcgcgctc ctccggggcg ggcggttcgc gcagggcgcg ggcgaggcag cggcgcccgg 8461 cgtcgggcgc cccggcccgc agatactccc gggcggcctc cctgaggtgg cgcaccaccc 8521 aggagtcgcc ctcggggtgc atctccagca gatggcgccc ggcggccgcg gagcccaggc 8581 ccgcggcgag caccacggtg gcggcctggc cgtgcatggc cacgcgcagc gcgccgggga 8641 tggcctggta gacggcggtg gcgatgagcg ggtggaggaa ttccagcggc tgggcaccgc 8701 gggcgctctg ccgcggcggg gcgaggatac gggcgtccgc gagccgcgcc acctgctcgg 8761 cggtctcggt ctcgctgagc ccggcgacgt tggccgtcag cgacggggtg gcctcgatac 8821 cgaggacggc gacggcccag gcgaggcgga cggcggcggt gccgagccgg gtcagccggt 8881 cgccgagacc gctgtccttc gcggcggcga ccagttcgcg cagggctccg aggttgaccg 8941 tctgcggttt cagatcgcgg tcacggacct tggcggtcag ctcgacgacc tcgaaggggt 9001 tgccgccggt cacgcccagc actcgcggca gacgctcgtc ggctctcgcg aggacgtccc 9061 gcacgatctg cgacccgggc ggatgagcgg tgtcgagcac atgcgcgcgc gagccttgcc 9121 tgttcggtga agccgcgcaa cgacgacggc gtcggcggtc aggtcttccg ggcggtagcc 9181 gacggcgagc agcaggggca ggttccacgg cgcgggcggc gaacccggag gagccagtcc 9241 agggattcgg ggtcggccca gtggacgtcg tccaggatca tgacgaccgg ggcgtgctcc 9301 accgcgaacc gggtgaccag ccagtccagg ccgtcgcgca cgccctgcgg atcgggcgcg 9361 ccgccgctcc cggagaccac caggcccacg gcgggcgcga cgatgtcgta ccagctgccc 9421 aggattctgc ggtgctcctc ctcgccggtg gtcgcgagca cgggctggaa gagctgccgt 9481 acgacgtgga acgcggcgcc ctgttcgtgc tcgccgccgc gcgccgacat cacggtgcag 9541 ccgcggtggg cggctctgcg gcgcatctcg ccgagcagcg cggtcttgcc gaggccgccc 9601 ggcccggcga aggcgatcac tccgccggtg cgggtgccgg acggatcgcc ggggtcggat 9661 ccgcacagat cggtcaacgc gtggtcgacc gccgcgagtt cggcctcccg ctccagcagt 9721 gcccgacgtg tccggtcctg ccggtccctc atgtccgcca cgttcgatcc ccttcggcga 9781 gtaacgccga gcgtagcctg tctggcacgc tccgtagccc ggtatgcggg tatttccttc 9841 tggcattgcc aatggcacac gccaattcaa ctcgcgctct atcgatggca cgttcaccac 9901 gcgaggatga ccggattcat cgggtcggcc cgtcgccgcg gggggttgtg gtattgggcg 9961 gcgcggcctt ccccggagcc cgaagggggg cgataccgcc atgaacgcga cgtacacgac 10021 tacttcgcgc ccgcacgccc ggcatgcggc actgctgagc cgggcggccc tgctcgacat 10081 tccggcctcg gccgacccca gccccggaac cggggccgcc agagtgcaca ccgtccagtg 10141 gctgtcgcgg tacggcgtgt tccgggccgg tggcgcggtc gccgagtacg acgcgctccg 10201 attcgacctg ctgaacggcc tgttctatcc ccggacgacc ggtgcggaac tggacgtggg 10261 caatgatctc atcggctggt acttcgtctt cgatgatcag ttcgacggtg aactcgggtg 10321 ccgtccggag gcggtggcgc ggatggtgcg ggacgtcata cgggtcaccg aggagccgga 10381 cgacgcaccg gggcagggcg gcgggcccct gctggagagc ttccgtgatc tgtggcggcg 10441 catccacgcg ggccgcccac cggtatggcg ggaacgtttc cgccaccact ggctggagta 10501 tctgcactcc tatcaccgcg aggcgctcga ccgctccggc acacaagggc cgccgctctc 10561 ggtggacgcc gtgctggcgc tgcgccgcca ctcgatcggc gtgcagccgt gcctggacct 10621 gaacgagcgc ttcggcggct acgccctccc cgccgcgctg cacggcggcc atccgctggc 10681 ccggatgcgg gaggccacgg acgacgtcgt cgtcttcacc aacgacatcg cctccctgga 10741 caaggagctg gccgccgggg acctccacaa caccgtcatc gtccgccacc agtgccacgg 10801 cggcaccctg gaggacgcgg tcgagcacat cgcgggcctc gccaacgcgc gctaccgctg 10861 gttcgagcag accgcggacc ggctgccccg gctgctcgcc gacgcgggtg cggggacgga 10921 tctgcgccgg gacgtggacc actacgtgga cgggatgcgt gacgtgatgt gcggcaacct 10981 gggctggtcc ctgcggacgg cccgctacga cgagcggggc atagcggcgg tcagcgacgg 11041 ccgccaacga ccgtgggccg gactcagcgc ccccggttcc ggctgaccgg atccgctacg 11101 tacgaacggc ccgccgcggc gggccgttcg ggtatcaagg ggcatgtgaa cgacaccctc 11161 aacctgtgga aggcggggct cgccgaggcc cccgacgcca tctggcagca caccggtctg 11221 cgcgtgctga tcctcgccga caacgcactc acccgcctcc cgcctgccct cggacggctg 11281 ctgcggctgc acaccctgga cctcggccac aaccggctcg ccgggatccc ggaggagatc 11341 ggcgagctgt cggggctgac ccgctgcctc tatctgcacg acaaccggct cccccggctg 11401 ccgcgttccc tcgggcggct cgaccggctg ggctacctca acgtcggcga gaacccgctc 11461 gggggtctgc cggaggaact cggcggcatg gcggggctgg tggagctgcg cgcgcagcac 11521 gccgaactga ccgcgctgcc cggctcgatc gggcagctca gcgcgctgcg ggagctgtgg 11581 ctgcgcggca accggatcac cgccctgccc gccggggtgt ccgcgctccg cgcgctgcgc 11641 cagctggagc tgcgggagaa cgcgctgagc gaggtgcccg agccgctgcg cgggctcccg 11701 cgcctgcgcc acctcgatct gcgcggcaac cggatccgga cgctccccga ctgggtcgcg 11761 gagctgcccg ccctggagaa gctcgacctg cgctggaacc cgctcgacga gggcgtcgac 11821 gacggcccgg tcgtccgggc gctcggcgag cggggctgcg tcgtgctcgg atgaggccgg 11881 ggccgcgccg cgccgaagcc cggacgaggc gtcaggtcag gacgccgagg cccggacgag 11941 gcgtcacgtc aggtcgaact cgccctcgcg cgcgcccagg acgaaggcgc gccactcggc 12001 cggggtgaag atcagggccg ggccttcggg acggcggccg tggcgcatcg cgatgaagcc 12061 ctcgacgaag gcgatctcga catcgcccac cccctggctg ctcgactgcc actgggcgct 12121 tgtgaggtcg aggtcgggct tctcgccatt gcccctgagc ggctgtgcgg tcgtggtggt 12181 gtctgccacg tgcggctcct cccggatcgt cgtcccggcc ccaccctagc gatcgcggcc 12241 ggtgccggac aggccacgaa aggaggacgt gatctgtccg gcgggtgtcg tccgggtgca 12301 tgcctcatgt ggacggaggg gccgccccga ccacccacat ggcgaagaac tgcgaacccc 12361 cgccgtaggc gtgaccgagc gccgtgcgca ccccctcgac ctggtgctcg cccgcccggc 12421 cgcggacctg gagggcggct tcggcgaagc ggagcatccc ggaggcgccg atcgggttgg 12481 tggacagcac cccgcccgag gggttgacgg ggaggtcgcc gccgatctcg gtcaccccgg 12541 actcggtgag cttccagccc tcgccctccg ccgcgaagcc caggttctcc agccacatcg 12601 gctcgtacca gctgaacggc acgtacatct cgatcgcgtc gatctcccgg cgcgggtcgg 12661 tgatcccggc ctgccggtag acgtcggcgg cgcagtcgcg cccggcgcgc ggcgagacgc 12721 agtccttgcc cgcgaagagc gtgggctcgc tgcgcatcgc gccgccgtgc atccaggcgg 12781 gcggccgggg ggcgcgggag gcaccggtgc ggtcggtgag caccatggcg cacgcgccgt 12841 cggaggaggg gcaggtctcg gagtagcgga tggggtccca cagcatcggc gaggactgca 12901 ccttctccag cgtcagatcc tgttcgtgga gatgggcgta ggggttgagc agggcgttgc 12961 ggcggtcctt gtacgcgacg agcgcgccga tcgccggggg cgcgcccgtg cgccgcatgt 13021 acgcgcggac gtgcggcgcg aagaatccgc ccgccccggc cagcagcggc tgctggaagg 13081 ggacgggcag cgagagcccc cacatggcgt tggactcgga ctgcttctcg aacgccaggg 13141 tgagcacggt gcggtggacg cgggcggcga ccaggttggc ggcgacgagc gcggtggagc 13201 cgccgaccga tccggcggtg tgcacgcgca gcatgggctt gccgaccgcg ccgagcgcgt 13261 cggcgaggta cagctcgggc atcatgacgc cctcgaagaa gtcgggcgcc ttgccgatga 13321 ccacggcgtc gatgtccgcc caggtcagct cggcgtcctc cagggcccgt acggcggcct 13381 cccggaccag tccggcgatc gagacgtcgc gccgggcggc ggtgtgcttg gtctggccga 13441 ttcctacgac ggccaccggt tccttgctca ctggacggct caccgggctt ccccttccag 13501 gacggcgacc aggttctgct ggaggcaggg gccggaggtg gcgtgggcca gcgcccggtc 13561 ggcgtcgccg cggtggaggg cggcggcggc ctcgccgagc cggatgagcc cggcggccat 13621 catggggttc gcggccggtg ccccgccgga cgggttgagg cgtacaccgt cgtccagctc 13681 cagttcgcgg cgcaggatga tctcctgcga ggtgaacggg gcgtggagtt cggcgaggtc 13741 gacgggcgcc tcgaaggccc cggcgcgggt cgcggcgagc cgggtcgacg gggagcgggt 13801 gaggtcccgg acgcccaggc cgtgcggttc gatgcggtgg tccatgccgc ggatccacgc 13861 ggggcgggcg cacagccgcc gcgcggtgtc cccggcggcg agcaccacgg cggccgcgcc 13921 gtcgccgatg ggcgggcagt cgtggcggcg cagcgggcgc accaggtacg gggcgtcgag 13981 gagggcgccg ggcggggcgg agcgggtcac ctgggcgtgc cggttgtccg cggcggcgtt 14041 gcggccgcgc gcggcgacct cggcgagggc gcgttcgtcg gtgtcgcccg cgtcgatgag 14101 cgcctgggcc tggagggcgg cgagggagac cgagtcgggc cacaaggggg cgacgtagta 14161 cgggtcgagc tggcgggtga ggacctcggg cagatcgccg ggcgaggact ttccgtagga 14221 gtagacgagc gcggtgtccg cctcgccggt cagcagcttg acccaggctt cgtagagcgc 14281 ccaggcgccg tccatctcga cgtgggactc ggcgatgggc ggccaggcgc cgacgccgtc 14341 gagcgccatg gtgaaggaga aggcgcggcc cgcgaggtag tcggaggagc cggagcaggt 14401 gaagtcgatc tcgcccgccc tcaagcccac cgcgccgagc acctggtgga ggacgggcat 14461 cagcatctcg acctcggaga cctccgcgct ggtgcgccgg gtgccgctct gcccgaaggc 14521 gacgatggcg acgtctcgca tctacaacag ctccttgtag gtgtcgtagt cggcgtcggg 14581 ttcgccggtg ggccggtagt ggtcggggta gcggccgccc tcggtccata cgggcgtcac 14641 ccgcagtccc atgcgcacct ggtcgtacgg gatgccgccg atgcggccgt gcagggcgag 14701 atcggcaccg tcgagggcga tgtgcgcgta gacgtacggc acttcgatat ccagattgcg 14761 ggccttgatg ttcacgatgc agaaagtggt gacggtgccg cccgggccca cctcgacctg 14821 ttcctcggtg gcgacgccgc aggtggggca ggcgccgcgg ggcggtacgt acaccttgcg 14881 gcaggacggg cagcgttcgc cgacggtctt ccgcccggcg agggcggcga ggtagcggga 14941 ctgggcgcgg ccgggcgcgt aggtgtagtc gagacgggcg ggggcgacga tgccggtgac 15001 ggggtcggcg aacaccccgt cgtgggggcc gggttcatga gtggccgggc cgtcgtacgg 15061 ttcgaagcag gcgatgtcgg tgatggagcc ctcgcgctcc tcggcccagc ggacccgtac 15121 ccgcatgccg gtgcgcacgg cgtccggccc cggcgcgtcg agggcgtgca gcagggcggt 15181 gtcggcgccg tcgagccgta ccagcgccca ggcgaagggg gtggacaggg gctggccgcg 15241 gcgcggggcc gggttccagg cccaggtggt gacggtgccg gtgggggcga cctcgaccag 15301 gtcgcgcagt tcggcggcgg tgtccgggtc gtattcgacg ggcgggacga gcacccggcc 15361 accggcggtc cgtacgccga gcacggtgcg ctcgcgcagg cccgtgagga aggcgctctg 15421 gacggggccg agggagcggg tgaaggggaa ctcgaccacg agaggggcct tcagcacctc 15481 gggggcggga gccggtgtca tggggcgtct ccttctgctg gcagcggggc cctaggcccg 15541 gcggtagacc ggggggcgtt tctccgcgaa ggccttcgat ccctctttgg cgtcggcggt 15601 gtcgaagatg ggccagccgc gctcgagttc ggacgcgagg ccatcggttt cggtcatctc 15661 ggcggtctcg tagacggatg ccttgaccgc ctcgacggcg agcgggccgt tggcgttgat 15721 gagttcggcg atctccaggg ccttcttcag cgcggtgccg tcgtccacca cctggccgat 15781 cagcccgatc cgctcggcct ccccggcggc gtacgggcgg ccggtgagca gcatctccag 15841 ggcgtgggtg cgcggcacct ggcgggccag ccggaccgtg gagccgccga tggggaagag 15901 cccgcgccgg acctcgtaca gcccgaaggt ggcgccgcgg cccgccaccc ggatgtcggt 15961 gccctggagg atctcggtgc cgcccgccac gcagtggccc tcgacggcgg cgatcaccgg 16021 tttgcgcggc cggtggtggc ggagcatggc cttccagtgg aggtcggggt cggccttcag 16081 ccggtcccgg tagtgctgcc cctccatccg gccgccgccc gcgagcgcct tgaggtccat 16141 cccggcgcag aagacaccgc cggcgccggt gagcacgacg gaccggacgg tgtcgtcctc 16201 gtcggcctcg atccagccgt cgtacagccc gaccagcatg ggcaacgaga gcgcgttctt 16261 ggcctcaggc cggttgagcg tcagcaccag cgtggcgcct atgcgctcga cgatgaggtg 16321 ttcggtcccg tgcggcacag cagtcctccc gtctcagacc tagaacaggt tgcaggagcg 16381 gcggagcgac ttcaatagga atctgatggg cagtcagatt ttttggccgc ggcccttccc 16441 acctctcccc cgcggtgctg tcatgagcgc cgagcccgcc cgatgtcagg tcaggaggag 16501 ccgtggagta caaccttgcc gacctgttcg agtcgatcgt ggacacggtg cccgacagag 16561 aagcgctggt gtacgccgac catccgggca ccggcgccga gcggcggctg agctacgccc 16621 agctggacgc cgccgccaac cggctcgccc accacctgag gaacagcggg gtcgcaccgg 16681 gcgagcatgt ggggctgcac ctgttcaacg gtgtcgagta cctccagacc gtcctggcct 16741 gcctgaagat ccgggccgtc ccggtgaacg tcaactaccg ctatgtggaa gacgagctgg 16801 tctatctcta ccgcgatgcc gatctgaccg ccctggtcta cgacgccgag ttcggcgacc 16861 gggtggccgc cgcgctgccg cgtacggaca ccctgcgcca cctggtccag gtgggcgccg 16921 gggagggcgc gcccggcgcc gtcccgttcg ccgaggccga ggcgtcgggc gcggccgggc 16981 gcggcttcgc gccccgctcc gcggacgacc gcttcatcat ctacaccggc ggcaccaccg 17041 gcatgcccaa gggcgtgatg tggcggcagg aggacctctt cttctccggg ctcggcggcg 17101 gcgcgccgac cggcgttccg gtcggccgcc ccgaggagct ggccgaacgg gtggcggcct 17161 ccggcgacgg cctggtcttc ttccccaccg caccgctgat gcacggcacc tcgaccctca 17221 cgaccttcat cggcctcaac ttcggtcaga aggtggtcct ccaccggaag ttcgtgcccg 17281 aggaggtgct gaggacgatc gaaaaggaga aggtcagtac cgtgtccctg gtcggggacg 17341 cgatgctgcg gcccctggtg gacgccctca ccggaccgct gaaggacatc gacctctccc 17401 cgctgctcag cgtcagcagc tccggggcga tcctctcgga caccgtgcgc gcccagttcg 17461 ccgcgctcgc gccgcacacc ctgatgctca acaacttcgg ctcatcggag tccgggttca 17521 acggcaccgc caccgaggac tccggccccg agcggggctt ccgcgtgcgt gtcaacgacc 17581 gtacggccgt cgtcgacccg gcgacccacc gtcccgtcgc gcccggggaa ccgggccggg 17641 tcgcccagcg cggccatgtg ccgctcggct actacaacga cccgaagaag acggccgaga 17701 ccttcttcga ggcggacggc gaacgctggg tgctcctcgg cgacatggcg acggtcgacg 17761 aggacggcgt gatcacggtc ctcggccggg gttcccagtg catcaacacc ggtggcgaga 17821 aggtgtaccc ggaggaggtc gaacaggccc tgaaggccca tccggacgtg tacgacgcgc 17881 tggtggcggg cgtccccgac gagcgctggg gcaatcgcgt ggcggccgtc gtccagccgc 17941 gggagggggc cgatgccctc accgccgacg cggtgcggga ccactgccgc acccggctcg 18001 ccgggtacaa gatcccccgt accgtcgtct tcaccgaccg catccagcgc tcccccagcg 18061 gcaaggccga ctaccgctgg gcccgcacgg tcgcggccgg agacggcacc ggggcgtagc 18121 ggcccgcgac cctatcgagt ggtcaggacg cgggcggcga agtcgcggac cgcgtccagg 18181 acgcccgtgc cgctgtgtcc gacccccggc acgatgtcga gggtgacgtc gatcccgagc 18241 gcgacgtagt tgtcgcgcag tgcggtgatc cgctcgaccc gggtccggcc cagggcgtcg 18301 gcgccgtcca tccagttgga gtcgcccggg ttgttgatct cccaggtctc ggtgtcctcg 18361 gcgccgacca ccatgtggac cgccacctta cggatctcct ccagccgcac cggcgcaccg 18421 aagcgctcct cgaaaccggc cgtgcccagc caccattcac ggtccgggtc gatcagcgtg 18481 acccggcccg gcgcgccgat cgacacggcg cacagccgct ccgggtggag gtagaggaag 18541 cggtgggcga actgcccgcc gcccgagaag ccctggagca tgaaccggtc ggtgtcgacg 18601 gtgaagcgcg tcccgacctc gtcgacgatc gccagcagct cccggtcgta gcggatgccg 18661 tcgtactcga tgaacttgaa gttgtgcagg tcgtccgggt cgccgatggc cgcggggaac 18721 agcggggtga ggatgacgac gccgtgccgc tcggagaact ccgccatcgc gttccggtac 18781 tcggccgccg tgcggccggt gccgtgctgg atcaccagca gcgggagcgg tgtggtggtg 18841 gtctcgtgca cggagggcac gtgcaggctg taggagaacc gctgatcgtg ctgtgaggcg 18901 aagaaggtgg tggcgccggt gcggtagaac gccttggtgg tcttgatgcg cggtgtcaca 18961 tgtcctcctg cgatgcgccg ccaccgacat ggggcggtgc ccgtcacgat cacgggtgcg 19021 tcggcggcgg ctcaagatga ttgccgcgca ggcgtcaatg accgggacgg tgtcagcggc 19081 gcagtgcgga gagcagatcg acgccgaggg tgcggacggc ttcctcgtcc agctggtaat 19141 gcacccgggc gccctgccgg tgggtgtgca ccattccggc ctcccggagt ttgcgcagat 19201 ggcgcgacat ctgcggcggg gtggtgtcga agtggctggc cagctcggtc gtcgtcatcg 19261 actgccgcag caggacgcgg cacacccgga cgcgcagggg ctcgtccagc gcccgcaccc 19321 ggcgcagcac ctcgtccatg gcgggcggct ccccgtcgcc gtctccccgc accgggtact 19381 gcacgaccac cggatagccg gggtagtgct tgatcgccac atgcgggttg atgtgccgcg 19441 agggcaccag caggcacggg acgtcggcga ggctggcccg accgttgtac agcttgtcga 19501 agacgacccg cggcggatcg tcctcgaccc gggcggtggg gaagtcggcg agcgcccggg 19561 cgccgtccag ccggtgcttc tggaagcgca tacggacgtc cgcctccagt gcgcggcgca 19621 gccgggccca ctccccctcg aacagctcgt cggcggcggc gtgcaggaag tcggtgaggt 19681 cctcccggaa cgcggcgggc ccggcgagca gccgcactcc cagcgcgaac cggccgtccg 19741 acatctgccg cagcctgccg aggaagcgtt cgggggtgtt gcccgggaca ccggtcggct 19801 ggtggctgtt ctggccgatc agggcctgtt cggtcatggc cgtgaacgtc gcctcgggca 19861 gctcgccgat gtcggccagc tcctcctcca gggagcgctc gggcccggga gtgaggggca 19921 gcagatagcg ggcgcggaac gcgccccaca gcggtgccca ctgcgcggcc cgcgccagca 19981 gccgctcgtc cgcgccctgg agcacggcgc cgacccagcg gcggctggcc ggatggtgcc 20041 ggggctcgtc cagcgcgtgc aggcaggcgc acagctcggc gagcggggac agccgtccgg 20101 cgatgcgctc ctcgggagcg gggcccaggt cgatcactac gggcatgcgt cgacggtccg 20161 ggattgacgc cttgctgtca atcgtcttgt ggccggttcg cgaggggcgc aggctccggt 20221 catcttcccg gccgcccccg atcccgcccc cgatttccgc acctctccgc gacggagcgt 20281 ttccatgccc cctctcctcc ggaacggtcc gcgcgtcgtg ctgaccgtca ccctgctggc 20341 cacggtgagc agcgcgtgca ccatcggttc cgccgacgac tccaccgcgg ccgccggcta 20401 cccctcccgc ggcctgtcca tcctggcccc cggcagcgtc ggcggcggct gggacgcccg 20461 ggcccgcggc atgagcgccg cgctcaccgg ctgcaagatc atcgacgagg acgtcacggt 20521 caccaacaag ccgggcgcgg gcggagccat cgggctcgcc cggatggtcg gccgcagcgg 20581 cgacccgtac cagctgatga ccatggacac ggtcaccatg gccgggggcg cggtgcagaa 20641 cgactccccg gtcggcctct cgtctctcac ccccatcgcc gggctgaccg tcagccccag 20701 cgtgatcgtg gtgcccgccc gctccccgta ccgcgatctg acgtcggtga tggcggccat 20761 gaagcggaac cccaagggca tgtcctgggt gggcggttcc ctgggcggcc ccgaccacat 20821 caccgtcgcc tccctcgcca aggcccgggg catccccgtc aagaagatca cctacgtgcc 20881 gaccggcggg ggcggcgaag tgctcaacct gctgctgagc ggggcgtcca aggtcggcat 20941 gtcgacactg accgagatcc gcccgcagat cgaggcgggc aagctccggg tcctcgcgat 21001 cagcggcgac gagcgtcccg aggggctgaa cgccccgacc ctcaaggacc tcggatacgg 21061 cggatcgagc gtggtgagca ccggcg //