LOCUS       NZ_GG657754            21086 bp    DNA     linear   CON 01-MAY-2024
DEFINITION  Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome
            shotgun sequence.
ACCESSION   NZ_GG657754
VERSION     NZ_GG657754.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces himastatinicus ATCC 53653
  ORGANISM  Streptomyces himastatinicus ATCC 53653
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group.
REFERENCE   1  (bases 1 to 10901646)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Annotation of Streptomyces hygroscopicus strain ATCC 53653
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10901646)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q.,
            Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z.,
            Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A.,
            Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L.,
            Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S.,
            Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   3  (bases 1 to 10901646)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q.,
            Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z.,
            Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A.,
            Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L.,
            Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S.,
            Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Arachne v. April 2007
            Genome Coverage                   :: 6x
            Sequencing Technology             :: ABI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_000158915.1-RS_2024_05_01
            Annotation Date                   :: 05/01/2024 03:02:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,680
            CDSs (total)                      :: 9,608
            Genes (coding)                    :: 8,720
            CDSs (with protein)               :: 8,720
            Genes (RNA)                       :: 72
            rRNAs                             :: 4, 1 (5S, 16S)
            complete rRNAs                    :: 4, 1 (5S, 16S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 888
            CDSs (without protein)            :: 888
            Pseudo Genes (ambiguous residues) :: 0 of 888
            Pseudo Genes (frameshifted)       :: 423 of 888
            Pseudo Genes (incomplete)         :: 530 of 888
            Pseudo Genes (internal stop)      :: 36 of 888
            Pseudo Genes (multiple problems)  :: 97 of 888
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:01:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1521334
            Orig. end                         :: 1542420
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG657754.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation was added to the scaffolds in August 2010.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(151..166)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     misc_feature    complement(385..397)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     misc_feature    complement(413..425)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            509..>1148
                     /locus_tag="SSOG_RS05755"
                     /pseudo=""
     CDS             509..>1148
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033044.1"
                     /locus_tag="SSOG_RS05755"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYAASSSVSAPPRPYRRQLPGNGPYLDPAPGGRARRTAAVGSVPP
                     SGRLDVSGPQGAQLRTAIAAVHRICPEFNPVQVLRRSGRSVLLVGSTGRTTAVAKCLLD
                     HSPAWAERFRREIAMYRTFVRQRPPVRVPRLIAADPDNCALVIERMPGRVAAVQRHPAE
                     APPRADVRAALGAICRINQWRPPGDLFDAPVDYAARLSRYHELGLLTDRD"
     gap             1149..1864
                     /estimated_length=716
     gene            2189..3894
                     /locus_tag="SSOG_RS05760"
                     /old_locus_tag="SSOG_01159"
                     /pseudo=""
     CDS             2189..3894
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569434.1"
                     /locus_tag="SSOG_RS05760"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01159"
                     /product="peptidoglycan recognition family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHLTDAFTALFSAPHHSQGTEDARGDLARPLKVPEASVPEPRQLP
                     ARLRTLDRAAELTGLSAAELRGDAAANVRGGAALLAATQKRLGLPSSDDPADWYAAVAA
                     YPGADSAAAAAVFADDVYDVIRGGAARTTGDGERVTLDAVPGVAPGTGGSCGRSACRPP
                     SGIRTSRPPAMCPASGSRPPTSSSGTTTTATTTSATAPSPK"
     gene            complement(3896..6223)
                     /locus_tag="SSOG_RS05765"
                     /old_locus_tag="SSOG_01160"
     CDS             complement(3896..6223)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003908.1"
                     /locus_tag="SSOG_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01160"
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="WP_009713270.1"
                     /transl_table=11
                     /translation="MARWTLWYDTPAADWEREALPIGNGTLGAMVFGGVARERIQFNEK
                     SLWTGGPGGPGSAPYDSGNWREPRPGALAAVQRLIDEHGAAAPEDVAARLGQPRSRYGA
                     YQPFGDLWLEIPGAPESPDSYRRLLEIRKGVALVKYTAQGVRHRREFFASYPDRVIVGR
                     FDAAPGTVGFTLRHTSPRPGDHHVTAHDGRLTIRGALEDNGLRFEAQVRVMADGGTVTS
                     GEDGTLTVTGAHSAWFVLAAGTDYADTHPHYRGEDPHRTVTGTVDAAADRGYLTLLSRH
                     VRDHRALFDRTALDLGGRTPPRTPTDRQRAAYTGGESPADRALEELFFDYGRYLLIASS
                     RPGAPLPANLQGIWNDSVRPAWSADYHTNINLQMAYWPAHALHLAETAEPLHRFITALR
                     APGRITAREMFGARGWVVHNETNAYGFTGVHDWSTAFWFPEAAAWLVHHLYEHYRFTLD
                     TGFLRDTAYPAMREAAAFWLDTLRPDPRDGTLVVSPGYSPEHGDFTAGPAMSQQIVHDL
                     LTATLEAARTLGDDPALQAGLRRALDALDPGLRIGSWGQLQEWKADLDDPADTHRHASH
                     LFALHPGRQIAPDGPWAGAAAVSLDARGDGGTGWSRAWKVNFWARLRDGDRAHRLLAGQ
                     LTDSTLPNLWDTHPPFQIDGNFGAAAGIAQMLLQSHRAVLDVLPALPRRWPDGAVRGLR
                     AHGDLTVDITWREGRARTLTVAAGHDGPVRIRSDLFARPYTAHDDTTGRETAVRDDPGS
                     GDACTVTLAARGGRTYRFTARD"
     misc_feature    complement(6083..6085)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6236..6736)
                     /locus_tag="SSOG_RS05770"
                     /old_locus_tag="SSOG_01161"
     CDS             complement(6236..6736)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="SSOG_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01161"
                     /product="hypothetical protein"
                     /protein_id="WP_009713271.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPTGPDFDVLAMDPGDWPGDLGAGLLPAPDGTCQG
                     VFLRYDLFGGRGPAMIIGNLPEGSPAREVAEGQAPFEVTQLLAALGNEEQVQVVDTEDT
                     PVMHDDNLLIVRRIKLSEGRISCAQFDRSDGVLVTIASWDRPITDDLYRLLKPLPAEMF
                     QQG"
     gap             6978..7154
                     /estimated_length=177
     gene            complement(<7155..9100)
                     /locus_tag="SSOG_RS05775"
                     /old_locus_tag="SSOG_01162"
                     /pseudo=""
     CDS             complement(<7155..9100)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSOG_RS05775"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSOG_01162"
                     /product="ATP-binding protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLDTAHPPGSQIVRDVLARADERLPRVLGVTGGNPFEVVELTAKV
                     RDRDLKPQTVNLGALRELVAAAKDSGLGDRLTRLGTAAVRLAWAVAVLGIEATPSLTAN
                     VAGLSETETAEQVARLADARILAPPRQSARGAQPLEFLHPLIATAVYQAIPGALRVAMH
                     GQAATVVLAAGLGSAAAGRHLLEMHPEGDSWVVRHLREAAREYLRAGAPDAGRRCLARA
                     LREPPAPEERAAVLYELGCSAQLTEPAVTVNHLRAALEEPDLGSDLREAITYRLAQAYG
                     HSGRMEEAAQVVAAEVPRATSARTRLRMQAEQFMWSMFRADEKESPARSRRLARLADHL
                     TGRGMAERYLLGLRAWDAMTRGEPAATALHYAEEALGSGLSWTDDDWGFEVPILVALIF
                     LHCDQPGRAEALFNTGIAECERKGWRGSHLAFGITLLGYARLRRGALVEAEELAREGMR
                     IADLVGSSTPAHWTAVGTLIETLISRGRIREAQEFAAGHGGEILPQAVLCPDVPTVRGE
                     LLLASNLHGEARQQLADVGRRMDGRGMRNPVWCPWQLHMAQALALTDPNQAAEVADDAV
                     RRARQFGTHSAIGRALHSAAAVAQGSERIKLLAEAVSHLERSPSAYDLAVALVDHGAAL
                     RTRRPAPGGRGPA"
     gene            complement(9159..9752)
                     /locus_tag="SSOG_RS55670"
     CDS             complement(9159..9752)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="SSOG_RS55670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_245606576.1"
                     /transl_table=11
                     /translation="MRDRQDRTRRALLEREAELAAVDHALTDLCGSDPGDPSGTRTGGV
                     IAFAGPGGLGKTALLGEMRRRAAHRGCTVMSARGGEHEQGAAFHVVRQLFQPVLATTGE
                     EEHRRILGSWYDIVAPAVGLVVSGSGGAPDPQGVRDGLDWLVTRFAVEHAPVVMILDDV
                     HWADPESLDWLLRVRRPRRGTCPCCSPSATARKT"
     misc_feature    9815..9832
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            10001..11086
                     /locus_tag="SSOG_RS05780"
                     /old_locus_tag="SSOG_01163"
     CDS             10001..11086
                     /EC_number="4.2.3.157"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058745.1"
                     /locus_tag="SSOG_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01163"
                     /product="isoafricanol synthase"
                     /protein_id="WP_009713273.1"
                     /sec_met_domain="T1TS (E-value: 6.2e-73, bitscore: 245.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATYTTTSRPHARHAALLSRAALLDIPASADPSPGTGAARVHTV
                     QWLSRYGVFRAGGAVAEYDALRFDLLNGLFYPRTTGAELDVGNDLIGWYFVFDDQFDGE
                     LGCRPEAVARMVRDVIRVTEEPDDAPGQGGGPLLESFRDLWRRIHAGRPPVWRERFRHH
                     WLEYLHSYHREALDRSGTQGPPLSVDAVLALRRHSIGVQPCLDLNERFGGYALPAALHG
                     GHPLARMREATDDVVVFTNDIASLDKELAAGDLHNTVIVRHQCHGGTLEDAVEHIAGLA
                     NARYRWFEQTADRLPRLLADAGAGTDLRRDVDHYVDGMRDVMCGNLGWSLRTARYDERG
                     IAAVSDGRQRPWAGLSAPGSG"
     gene            11146..11874
                     /locus_tag="SSOG_RS48200"
                     /old_locus_tag="SSOG_01164"
     CDS             11146..11874
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173683.1"
                     /locus_tag="SSOG_RS48200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01164"
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="WP_039940678.1"
                     /transl_table=11
                     /translation="MNDTLNLWKAGLAEAPDAIWQHTGLRVLILADNALTRLPPALGRL
                     LRLHTLDLGHNRLAGIPEEIGELSGLTRCLYLHDNRLPRLPRSLGRLDRLGYLNVGENP
                     LGGLPEELGGMAGLVELRAQHAELTALPGSIGQLSALRELWLRGNRITALPAGVSALRA
                     LRQLELRENALSEVPEPLRGLPRLRHLDLRGNRIRTLPDWVAELPALEKLDLRWNPLDE
                     GVDDGPVVRALGERGCVVLG"
     gene            complement(11944..12189)
                     /locus_tag="SSOG_RS05790"
                     /old_locus_tag="SSOG_01165"
     CDS             complement(11944..12189)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713275.1"
                     /locus_tag="SSOG_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01165"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_009713275.1"
                     /transl_table=11
                     /translation="MADTTTTAQPLRGNGEKPDLDLTSAQWQSSSQGVGDVEIAFVEGF
                     IAMRHGRRPEGPALIFTPAEWRAFVLGAREGEFDLT"
     gene            complement(12305..13471)
                     /locus_tag="SSOG_RS05795"
                     /old_locus_tag="SSOG_01166"
     CDS             complement(12305..13471)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057880.1"
                     /locus_tag="SSOG_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01166"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_009713276.1"
                     /transl_table=11
                     /translation="MSKEPVAVVGIGQTKHTAARRDVSIAGLVREAAVRALEDAELTWA
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPPAIGA
                     LVAYKDRRNALLNPYAHLHEQDLTLEKVQSSPMLWDPIRYSETCPSSDGACAMVLTDRT
                     GASRAPRPPAWMHGGAMRSEPTLFAGKDCVSPRAGRDCAADVYRQAGITDPRREIDAIE
                     MYVPFSWYEPMWLENLGFAAEGEGWKLTESGVTEIGGDLPVNPSGGVLSTNPIGASGML
                     RFAEAALQVRGRAGEHQVEGVRTALGHAYGGGSQFFAMWVVGAAPPST"
     gene            complement(13480..14541)
                     /locus_tag="SSOG_RS05800"
                     /old_locus_tag="SSOG_01167"
     CDS             complement(13480..14541)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433333.1"
                     /locus_tag="SSOG_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01167"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_009713277.1"
                     /transl_table=11
                     /translation="MRDVAIVAFGQSGTRRTSAEVSEVEMLMPVLHQVLGAVGLRAGEI
                     DFTCSGSSDYLAGRAFSFTMALDGVGAWPPIAESHVEMDGAWALYEAWVKLLTGEADTA
                     LVYSYGKSSPGDLPEVLTRQLDPYYVAPLWPDSVSLAALQAQALIDAGDTDERALAEVA
                     ARGRNAAADNRHAQVTRSAPPGALLDAPYLVRPLRRHDCPPIGDGAAAVVLAAGDTARR
                     LCARPAWIRGMDHRIEPHGLGVRDLTRSPSTRLAATRAGAFEAPVDLAELHAPFTSQEI
                     ILRRELELDDGVRLNPSGGAPAANPMMAAGLIRLGEAAAALHRGDADRALAHATSGPCL
                     QQNLVAVLEGEAR"
     gene            complement(14542..15501)
                     /locus_tag="SSOG_RS05805"
                     /old_locus_tag="SSOG_01168"
     CDS             complement(14542..15501)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058750.1"
                     /locus_tag="SSOG_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01168"
                     /product="OB-fold domain-containing protein"
                     /protein_id="WP_039936668.1"
                     /transl_table=11
                     /translation="MTPAPAPEVLKAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRT
                     AGGRVLVPPVEYDPDTAAELRDLVEVAPTGTVTTWAWNPAPRRGQPLSTPFAWALVRLD
                     GADTALLHALDAPGPDAVRTGMRVRVRWAEEREGSITDIACFEPYDGPATHEPGPHDGV
                     FADPVTGIVAPARLDYTYAPGRAQSRYLAALAGRKTVGERCPSCRKVYVPPRGACPTCG
                     VATEEQVEVGPGGTVTTFCIVNIKARNLDIEVPYVYAHIALDGADLALHGRIGGIPYDQ
                     VRMGLRVTPVWTEGGRYPDHYRPTGEPDADYDTYKELL"
     gene            complement(15532..16338)
                     /locus_tag="SSOG_RS05810"
                     /old_locus_tag="SSOG_01169"
     CDS             complement(15532..16338)
                     /NRPS_PKS="Domain: ECH (15-260). E-value: 1.6e-50. Score:
                     163.6. Matches aSDomain: nrpspksdomains_SSOG_RS05810_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173688.1"
                     /locus_tag="SSOG_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01169"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_009713279.1"
                     /transl_table=11
                     /translation="MPHGTEHLIVERIGATLVLTLNRPEAKNALSLPMLVGLYDGWIEA
                     DEDDTVRSVVLTGAGGVFCAGMDLKALAGGGRMEGQHYRDRLKADPDLHWKAMLRHHRP
                     RKPVIAAVEGHCVAGGTEILQGTDIRVAGRGATFGLYEVRRGLFPIGGSTVRLARQVPR
                     THALEMLLTGRPYAAGEAERIGLIGQVVDDGTALKKALEIAELINANGPLAVEAVKASV
                     YETAEMTETDGLASELERGWPIFDTADAKEGSKAFAEKRPPVYRRA"
     aSDomain        complement(15559..16293)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSOG_RS05810_ECH.1"
                     /evalue="1.60E-50"
                     /label="SSOG_RS05810_ECH.1"
                     /locus_tag="SSOG_RS05810"
                     /protein_end="260"
                     /protein_start="15"
                     /score="163.6"
                     /tool="antismash"
                     /translation="TLVLTLNRPEAKNALSLPMLVGLYDGWIEADEDDTVRSVVLTGAG
                     GVFCAGMDLKALAGGGRMEGQHYRDRLKADPDLHWKAMLRHHRPRKPVIAAVEGHCVAG
                     GTEILQGTDIRVAGRGATFGLYEVRRGLFPIGGSTVRLARQVPRTHALEMLLTGRPYAA
                     GEAERIGLIGQVVDDGTALKKALEIAELINANGPLAVEAVKASVYETAEMTETDGLASE
                     LERGWPIFDTADAKEGSKAFAEK"
     gene            16503..18119
                     /locus_tag="SSOG_RS05815"
                     /old_locus_tag="SSOG_01170"
     CDS             16503..18119
                     /NRPS_PKS="Domain: AMP-binding (8-435). E-value: 3.1e-72.
                     Score: 235.3. Matches aSDomain:
                     nrpspksdomains_SSOG_RS05815_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458480.1"
                     /locus_tag="SSOG_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01170"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_009713280.1"
                     /sec_met_domain="AMP-binding (E-value: 9.4e-73, bitscore:
                     244.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESIVDTVPDREALVYADHPGTGAERRLSYAQLDAAA
                     NRLAHHLRNSGVAPGEHVGLHLFNGVEYLQTVLACLKIRAVPVNVNYRYVEDELVYLYR
                     DADLTALVYDAEFGDRVAAALPRTDTLRHLVQVGAGEGAPGAVPFAEAEASGAAGRGFA
                     PRSADDRFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGVPVGRPEELAERVAASGD
                     GLVFFPTAPLMHGTSTLTTFIGLNFGQKVVLHRKFVPEEVLRTIEKEKVSTVSLVGDAM
                     LRPLVDALTGPLKDIDLSPLLSVSSSGAILSDTVRAQFAALAPHTLMLNNFGSSESGFN
                     GTATEDSGPERGFRVRVNDRTAVVDPATHRPVAPGEPGRVAQRGHVPLGYYNDPKKTAE
                     TFFEADGERWVLLGDMATVDEDGVITVLGRGSQCINTGGEKVYPEEVEQALKAHPDVYD
                     ALVAGVPDERWGNRVAAVVQPREGADALTADAVRDHCRTRLAGYKIPRTVVFTDRIQRS
                     PSGKADYRWARTVAAGDGTGA"
     aSDomain        16527..17807
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSOG_RS05815_AMP-binding.1"
                     /evalue="3.10E-72"
                     /label="SSOG_RS05815_AMP-binding.1"
                     /locus_tag="SSOG_RS05815"
                     /protein_end="435"
                     /protein_start="8"
                     /score="235.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESIVDTVPDREALVYADHPGTGAERRLSYAQLDAAANRLAHHLR
                     NSGVAPGEHVGLHLFNGVEYLQTVLACLKIRAVPVNVNYRYVEDELVYLYRDADLTALV
                     YDAEFGDRVAAALPRTDTLRHLVQVGAGEGAPGAVPFAEAEASGAAGRGFAPRSADDRF
                     IIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGVPVGRPEELAERVAASGDGLVFFPTA
                     PLMHGTSTLTTFIGLNFGQKVVLHRKFVPEEVLRTIEKEKVSTVSLVGDAMLRPLVDAL
                     TGPLKDIDLSPLLSVSSSGAILSDTVRAQFAALAPHTLMLNNFGSSESGFNGTATEDSG
                     PERGFRVRVNDRTAVVDPATHRPVAPGEPGRVAQRGHVPLGYYNDPKKTAETFFEADGE
                     RWVLLGDMATVDEDGVITVLGRGSQCIN"
     CDS_motif       17013..17063
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SSOG_RS05815_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="SSOG_RS05815"
                     /protein_end="187"
                     /protein_start="170"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     CDS_motif       17658..17705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SSOG_RS05815_0002"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="SSOG_RS05815"
                     /protein_end="401"
                     /protein_start="385"
                     /score="13.4"
                     /tool="antismash"
                     /translation="VPLGYYNDPKKTAETF"
     gene            complement(18132..18959)
                     /locus_tag="SSOG_RS05820"
                     /old_locus_tag="SSOG_01171"
     CDS             complement(18132..18959)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174065.1"
                     /locus_tag="SSOG_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01171"
                     /product="hydrolase"
                     /protein_id="WP_039936669.1"
                     /transl_table=11
                     /translation="MTPRIKTTKAFYRTGATTFFASQHDQRFSYSLHVPSVHETTTTPL
                     PLLVIQHGTGRTAAEYRNAMAEFSERHGVVILTPLFPAAIGDPDDLHNFKFIEYDGIRY
                     DRELLAIVDEVGTRFTVDTDRFMLQGFSGGGQFAHRFLYLHPERLCAVSIGAPGRVTLI
                     DPDREWWLGTAGFEERFGAPVRLEEIRKVAVHMVVGAEDTETWEINNPGDSNWMDGADA
                     LGRTRVERITALRDNYVALGIDVTLDIVPGVGHSGTGVLDAVRDFAARVLTTR"
     gene            complement(19073..20146)
                     /locus_tag="SSOG_RS05825"
                     /old_locus_tag="SSOG_01172"
     CDS             complement(19073..20146)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174066.1"
                     /locus_tag="SSOG_RS05825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSOG_01172"
                     /product="DUF5937 family protein"
                     /protein_id="WP_009713282.1"
                     /transl_table=11
                     /translation="MPVVIDLGPAPEERIAGRLSPLAELCACLHALDEPRHHPASRRWV
                     GAVLQGADERLLARAAQWAPLWGAFRARYLLPLTPGPERSLEEELADIGELPEATFTAM
                     TEQALIGQNSHQPTGVPGNTPERFLGRLRQMSDGRFALGVRLLAGPAAFREDLTDFLHA
                     AADELFEGEWARLRRALEADVRMRFQKHRLDGARALADFPTARVEDDPPRVVFDKLYNG
                     RASLADVPCLLVPSRHINPHVAIKHYPGYPVVVQYPVRGDGDGEPPAMDEVLRRVRALD
                     EPLRVRVCRVLLRQSMTTTELASHFDTTPPQMSRHLRKLREAGMVHTHRQGARVHYQLD
                     EEAVRTLGVDLLSALRR"
     misc_feature    21003..21022
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.92"
                     /tool="antismash"
ORIGIN
        1 cggtgaagag gacggccagc accttgggca cgggatcgcg cggcgtctcg ccggtgtcga
       61 tccaacgccg cacccgcgag gtgtcggttg ccagctgcgg gtggcccatg gccgccgcgc
      121 gccggttcac gagcctcgcg agctcgccct tggaccagcc ggccaggccg aaaaggtccg
      181 caagacgggt gttgggttcc ctcgtcacgt caagccccca ggatcctcgg ctgacttgac
      241 agtaacgggc ccgtcacgag ccgtgcgact attcgccagg gttcgccagg gtccgccaga
      301 tggtgtgcca cccgcgcgcg ggtgtgatgt aggagtgcgc tacccggccc ggtgcgggtt
      361 ggaaaatccg cttggaaaat ccagttggaa aatgccagcg ggaaaccgcc cgttggaaaa
      421 cgccagccgc attccccagg gtgcggcccc gccccggggc cgggagcgta cgtacatacg
      481 tcggcacacg aagggatctg tctcgcccat gtacgcagcg tcgtcctccg tgtccgcccc
      541 acctcggccg taccggcggc agctgcccgg caatgggccg tacctcgatc ccgctcccgg
      601 cggccgcgca cggcgcaccg ccgccgtcgg ctccgtgccg cccagcggaa gactcgacgt
      661 gtccggtccc cagggtgcgc agctgcgcac tgccatcgcc gcggtccatc gcatctgtcc
      721 ggagttcaac ccggtccagg tgctccggcg cagcgggcgg tccgttctcc tggtcggttc
      781 gacgggccgc accacggcgg tcgccaaatg cctgctggac cactccccgg cgtgggccga
      841 gcggttccgc cgcgagatag cgatgtaccg gacgttcgta cgacagcgtc cacccgtccg
      901 ggtgccgcgg ctgatcgccg ccgaccccga caactgcgcc ctggtcatcg agcggatgcc
      961 cgggcgggtc gcggccgtgc agcgccatcc cgccgaggcg ccaccgcgcg ccgatgtgcg
     1021 cgccgcgctc ggcgcgatct gccggatcaa ccagtggcgg ccgccggggg atctgttcga
     1081 cgccccggtc gactatgccg cccggctctc ccgctaccac gagttggggc tgctgaccga
     1141 ccgggacann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1861 nnnngccccc gacaccacca gagacgcgga ccggaacggc gacagacccg tccccggccc
     1921 cagccggagg acggcgctgc gcaccgcggg cgccgccgcg tccgccgcct ttctgctccc
     1981 ggtcgtctcc gggaccccgg ccgcccgcgc cgatcagccg ccgggcggca caccgtcgcc
     2041 ggaaggggcc ggggcgctgc aacgggcctt cgcggcggcg gcgaaggagc acggggtgcc
     2101 gctgagcgtg ctgctgggcg tgtcgtatct ccagtcccgc tgggacggcc atcgtggcgc
     2161 gcccagcgtc accggcggct acggcccgat gcacctcacc gacgccttca ccgccctctt
     2221 ctcggccccg caccacagcc agggcaccga ggacgcccgc ggcgacctgg cgcggcccct
     2281 caaggtgccg gaagcctccg taccggagcc gcggcagctg cccgcgcggc tgcgcacgct
     2341 ggaccgggcc gcggagctga cggggctgtc cgccgccgag ctgcgcggcg acgcggcggc
     2401 caatgtgcgc ggcggcgccg ccctgttggc ggccacgcag aagcggctgg ggctgccgtc
     2461 gagcgacgat ccggcggact ggtacgcggc ggtggcggcc tacccgggcg ccgacagcgc
     2521 cgcggcggcc gccgtgttcg ccgacgacgt ctacgacgtg atccgcggcg gcgccgcgcg
     2581 caccacgggc gacggtgagc gggtcacgct cgacgccgtc cccggcgtcg cccccgggac
     2641 cggcggcagc tgcggtcgct cggcctgccg tcccccaagc gggatccgca cgtcgaggcc
     2701 cccggcaatg tgtcctgcga gtggatcccg gccccctacg agcagttcgg ggacaacgac
     2761 tacggcaacc acgacctcgg caaccgcccc ctctcccaaa tgatcgacta catcgtcatc
     2821 catgacaccg agggctcctg ggacaccacc atcaagctgg tccaggaccc gacgtatgtc
     2881 tcctggcagt acacgctgcg ctcctccgac ggccatatcg cccagcacgt accgctcaag
     2941 gacgtcgcct ggcacgcggg caactggtac gtcaacgcca agtccatcgg cctggagcac
     3001 gagggctttc tgaccgcgcc cgacgcctgg tacacggagg cgatgtaccg ctcgtcggcc
     3061 cggctggtga agtggctggc gcggcggtac ggcatcccgc tggaccggca gcacatcctg
     3121 ggccacgaca atgtgcccgg cacgaccgcc accaccatca agggcatgca caccgacccg
     3181 ggcccctact gggactgggc gcactacttc agcctcctcg gcgccccgtt ccaccgcacc
     3241 gcgggcgcct ccggcgggct ggtcaccatc cgcccggact acgagacgaa cgaaccggtg
     3301 tacaccggct gcgagacggc cggtcaggag tgcgccccgc acggttcgtc cgcggtgcgg
     3361 ctgcacacgg cgccgagcga cgacgccccg ctggtcaagg acatcgggct gcgtccggac
     3421 ggcgccgatt cgaccaccgg cgtcaacgac accggcgccc gcgccaccac cggccagcag
     3481 tacgcgctcg cgggccgtca gggcgactgg acggcgatct ggtacctcgg ccagcaggcg
     3541 tggttccgga acccgcggcg gcggcccacc gccgtgtacg gcaagggcct cgtcgtcacg
     3601 ccgaagccgg gcctggcgga ggtcccggtg tacgggcgcg cctacccgga gaaggaggcg
     3661 tacccggagg gcgtaccggt gcaggcggtc tcaccgctgc cgtacaagct gctcgccggg
     3721 cagcggtacg cgctggggct gcggacccag ggcgagtatc tgtgggcgac cacgttcgat
     3781 ggatccgggc acatcgtggt gcgcggtcag gacatctact accagatcca gttcgggcac
     3841 cgggtggcgt tcgtccgggc cgcggatgta cgggtgcggc gctccggccg atgagtcagt
     3901 cgcgggccgt gaagcggtag gtgcggccgc cgcgggccgc gagcgtgacc gtacaggcgt
     3961 ccccggagcc ggggtcgtcg cgtacggccg tctcgcggcc cgtggtgtcg tcatgggcgg
     4021 tgtacgggcg cgcgaacaga tcgctgcgta tccggaccgg cccgtcgtgt cccgccgcga
     4081 cggtgagggt acgggcgcgc ccctctcgcc aggtgatgtc gaccgtgagg tcgccgtggg
     4141 cgcgcagccc gcgcaccgcg ccgtccggcc agcggcgcgg cagggcgggc aggacgtcca
     4201 gcacggcgcg gtggctctgg aggagcatct gggcgatccc ggcggcggcg ccgaagttgc
     4261 cgtcgatctg gaacggcgga tgggtgtccc acaggttggg gagggtggaa tccgtcagct
     4321 gtccggcgag cagccgatgg gcgcggtcgc cgtcgcgcag ccgggcccag aagttgacct
     4381 tccacgcccg gctccagccg gtgccgccgt cgccgcgcgc gtccagggag accgcggcgg
     4441 ccccggccca ggggccgtcc ggggcgatct gccgtccggg gtggagggcg aagaggtggg
     4501 aggcgtgccg gtgggtgtcg gcggggtcgt ccagatcggc cttccactcc tggagctggc
     4561 cccaggagcc gatgcgcagc cccgggtcga gggcgtccag ggcgcgccgc agcccggcct
     4621 ggagggcggg gtcgtcgccg agggtgcggg ccgcctccag ggtggcggtg agcaggtcgt
     4681 ggacgatctg ctgggacatg gcgggccccg cggtgaagtc gccgtgctcg ggcgagtagc
     4741 cgggcgagac gacgagggtg ccgtcccggg ggtccgggcg cagcgtgtcc agccagaacg
     4801 cggcggcctc ccgcatcgcc gggtacgcgg tgtcccgcag gaagccggtg tcgagggtga
     4861 agcggtagtg ctcgtagagg tggtggacca gccaggcggc cgcctcgggg aaccagaagg
     4921 cggtggacca gtcgtggacg ccggtgaagc cgtacgcatt ggtctcgttg tgcacgaccc
     4981 agccgcgcgc gccgaacatc tcgcgggccg tgatccggcc gggggcgcgc agggcggtga
     5041 tgaagcggtg caacggctcg gcggtctccg cgaggtgcag ggcgtgggcc ggccagtagg
     5101 ccatctgaag gttgatgttg gtgtggtagt cggccgacca ggcgggcctg acgctgtcgt
     5161 tccagatgcc ctggagattg gcggggagcg gggcgccggg gcgcgatgag gcgatgagga
     5221 gatagcggcc gtagtcgaag aacagctcct ccagggcgcg gtcggccggg ctctcgccgc
     5281 ccgtgtacgc ggcgcgttgc cggtcggtgg gcgtgcgggg cggggtccgg ccgccgagat
     5341 ccagcgccgt acggtcgaac agggcgcggt ggtcgcggac atggcggctc agcagggtca
     5401 gatagccacg gtccgcggcg gcgtccacgg tcccggtcac ggtccggtgg gggtcctcgc
     5461 cgcggtagtg ggggtgggtg tcggcgtagt cggtcccggc cgcgaggacg aaccaggcgc
     5521 tgtgggcgcc ggtgacggtg agtgtgccgt cctccccgga tgtcacggtg ccgccgtcgg
     5581 ccatcacccg cacctgggcc tcgaagcgca gcccgttgtc ctccagcgcg ccgcggatcg
     5641 tcaaccgccc gtcgtgcgcg gtgacgtggt ggtcgccggg gcggggtgag gtgtggcgca
     5701 gggtgaagcc gaccgttccg ggggccgcgt cgaaccgtcc gacgatcacc cgatcggggt
     5761 acgaggcgaa gaactcgcgc cggtgccgca cgccttgggc cgtgtacttc acgagggcca
     5821 cgcccttgcg gatctccagg agtcgccgat agctgtccgg ggactcgggc gcacccggga
     5881 tctccagcca cagatcgccg aagggctggt aggcgccgta gcgggagcgg ggctgtccga
     5941 ggcgggccgc cacgtcctcg ggggcggccg caccgtgctc gtcgatcagc cgctggacgg
     6001 cggcgagggc gcccgggcgc ggctcacgcc agttgccgga gtcgtacggc gcggatcccg
     6061 gaccgccggg gcccccggtc cataacgact tctcgttgaa ctggatccgc tcccgggcca
     6121 caccaccgaa gaccatggcg ccgagcgtgc cgttgccgat gggcagcgcc tcgcgctccc
     6181 agtccgccgc gggggtgtcg taccagagcg tccagcgggc caccgggggt gtccctcagc
     6241 cctgctggaa catctccgcg ggcagcggct tgagcagccg gtacaggtcg tcggtgatcg
     6301 gccggtccca gctggcgatg gtgacgagga cgccgtcgct gcggtcgaac tgggcgcagg
     6361 agatccggcc ttcggacagc ttgatccggc gcacgatgag gaggttgtcg tcgtgcatga
     6421 ccggggtgtc ctcggtgtcc acgacctgga cctgctcctc gttgccgagt gcggccagca
     6481 gctgggtcac ctcgaacgga gcctggccct cggccacctc acgggccggg gagccctcgg
     6541 gcagattccc gatgatcatc gccgggccgc ggccgccgaa caggtcgtag cgcaggaaga
     6601 cgccctgaca ggtgccgtcc ggcgcgggca gcagccccgc gcccagatcg ccgggccagt
     6661 cccccgggtc catggccagg acatcgaagt ccggcccggt gggcgtggcg gcgctgcggc
     6721 ggcggaggaa ggacatgcgg acatggtacg tggcccgcca ccgtccccct gctggggagc
     6781 acccctcctc cggcccgccg tcacagcctc ttcacgggcc gccacacggc cccggcctcc
     6841 ggctcagtcc cggctcagtc cccggggagc gggtgcgggg ggcggtcggg gcggggggtg
     6901 cccagcaggg tggcgaggcc gccccggtcg gtgcccgcct tgcggtagac gccggacagc
     6961 agccgggcca cctcgcgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7141 nnnnnnnnnn nnnnagagcc ggtccccggc ctcctggggc aggccgacgc gtgcgcaggg
     7201 cggcgccgtg gtcgaccagc gccacggcca ggtcgtacgc ggacggcgag cgctccagat
     7261 ggctgacggc ctcggccagt agcttgatcc gctccgatcc ctgggccacg gcggcggcgc
     7321 tgtgcagcgc ccggccgatc gcggagtggg tgccgaactg gcgggcgcgg cgcaccgcgt
     7381 cgtcggcgac ctcggcggcc tggttcgggt cggtcagcgc gagggcctgg gccatgtgga
     7441 gctgccaggg gcaccagacg gggttgcgca taccgcggcc gtccatccgg cggccgacgt
     7501 cggcgagctg ctggcgggcc tcgccgtgca ggttggaggc gagcagcagt tcgccgcgga
     7561 cggtgggcac gtcggggcag agcacggcct gcgggaggat ctcaccgccg tggccggccg
     7621 cgaactcctg cgcctcccgg atccggccgc ggctgatcag ggtctcgatg agggtgccga
     7681 cggcggtcca gtgcgcgggc gtcgaggagc ccacgaggtc ggcgatgcgc atgccctcgc
     7741 gggccagctc ctccgcctcg acgagcgctc cgcggcgcag ccgggcgtat ccgaggaggg
     7801 tgatcccgaa cgccaggtgg gagccgcgcc agcccttgcg ctcgcattcc gctatgccgg
     7861 tgttgaacag cgcctcggcg cgtccgggct ggtcgcagtg gaggaagatc agggcgacca
     7921 ggatcggcac ctcgaagccc cagtcgtcgt cggtccagct caggccggag cccagggcct
     7981 cttccgcata gtgcagggcg gtggccgccg gttctccgcg cgtcatcgcg tcccaggcgc
     8041 gcaggcccag cagatagcgc tcggccatgc cgcggccggt gaggtggtcg gcgagccggg
     8101 cgaggcgccg ggagcgggcg ggggactcct tctcgtcggc gcggaacatg ctccacatga
     8161 actgctcggc ctgcatgcgc agccgggtgc gggcgctggt ggcgcggggc acctcggccg
     8221 cgacgacctg cgcggcctcc tccatgcggc cgctgtggcc gtacgcctgg gcgagccggt
     8281 aggtgatcgc ctcgcgcagg tcggagccga ggtccggctc ctccagggcg gcccgcagat
     8341 ggttgacggt gacggcgggc tcggtgagct gggcggagca gcccagctcg tacaggacgg
     8401 cggcgcgctc ctccggggcg ggcggttcgc gcagggcgcg ggcgaggcag cggcgcccgg
     8461 cgtcgggcgc cccggcccgc agatactccc gggcggcctc cctgaggtgg cgcaccaccc
     8521 aggagtcgcc ctcggggtgc atctccagca gatggcgccc ggcggccgcg gagcccaggc
     8581 ccgcggcgag caccacggtg gcggcctggc cgtgcatggc cacgcgcagc gcgccgggga
     8641 tggcctggta gacggcggtg gcgatgagcg ggtggaggaa ttccagcggc tgggcaccgc
     8701 gggcgctctg ccgcggcggg gcgaggatac gggcgtccgc gagccgcgcc acctgctcgg
     8761 cggtctcggt ctcgctgagc ccggcgacgt tggccgtcag cgacggggtg gcctcgatac
     8821 cgaggacggc gacggcccag gcgaggcgga cggcggcggt gccgagccgg gtcagccggt
     8881 cgccgagacc gctgtccttc gcggcggcga ccagttcgcg cagggctccg aggttgaccg
     8941 tctgcggttt cagatcgcgg tcacggacct tggcggtcag ctcgacgacc tcgaaggggt
     9001 tgccgccggt cacgcccagc actcgcggca gacgctcgtc ggctctcgcg aggacgtccc
     9061 gcacgatctg cgacccgggc ggatgagcgg tgtcgagcac atgcgcgcgc gagccttgcc
     9121 tgttcggtga agccgcgcaa cgacgacggc gtcggcggtc aggtcttccg ggcggtagcc
     9181 gacggcgagc agcaggggca ggttccacgg cgcgggcggc gaacccggag gagccagtcc
     9241 agggattcgg ggtcggccca gtggacgtcg tccaggatca tgacgaccgg ggcgtgctcc
     9301 accgcgaacc gggtgaccag ccagtccagg ccgtcgcgca cgccctgcgg atcgggcgcg
     9361 ccgccgctcc cggagaccac caggcccacg gcgggcgcga cgatgtcgta ccagctgccc
     9421 aggattctgc ggtgctcctc ctcgccggtg gtcgcgagca cgggctggaa gagctgccgt
     9481 acgacgtgga acgcggcgcc ctgttcgtgc tcgccgccgc gcgccgacat cacggtgcag
     9541 ccgcggtggg cggctctgcg gcgcatctcg ccgagcagcg cggtcttgcc gaggccgccc
     9601 ggcccggcga aggcgatcac tccgccggtg cgggtgccgg acggatcgcc ggggtcggat
     9661 ccgcacagat cggtcaacgc gtggtcgacc gccgcgagtt cggcctcccg ctccagcagt
     9721 gcccgacgtg tccggtcctg ccggtccctc atgtccgcca cgttcgatcc ccttcggcga
     9781 gtaacgccga gcgtagcctg tctggcacgc tccgtagccc ggtatgcggg tatttccttc
     9841 tggcattgcc aatggcacac gccaattcaa ctcgcgctct atcgatggca cgttcaccac
     9901 gcgaggatga ccggattcat cgggtcggcc cgtcgccgcg gggggttgtg gtattgggcg
     9961 gcgcggcctt ccccggagcc cgaagggggg cgataccgcc atgaacgcga cgtacacgac
    10021 tacttcgcgc ccgcacgccc ggcatgcggc actgctgagc cgggcggccc tgctcgacat
    10081 tccggcctcg gccgacccca gccccggaac cggggccgcc agagtgcaca ccgtccagtg
    10141 gctgtcgcgg tacggcgtgt tccgggccgg tggcgcggtc gccgagtacg acgcgctccg
    10201 attcgacctg ctgaacggcc tgttctatcc ccggacgacc ggtgcggaac tggacgtggg
    10261 caatgatctc atcggctggt acttcgtctt cgatgatcag ttcgacggtg aactcgggtg
    10321 ccgtccggag gcggtggcgc ggatggtgcg ggacgtcata cgggtcaccg aggagccgga
    10381 cgacgcaccg gggcagggcg gcgggcccct gctggagagc ttccgtgatc tgtggcggcg
    10441 catccacgcg ggccgcccac cggtatggcg ggaacgtttc cgccaccact ggctggagta
    10501 tctgcactcc tatcaccgcg aggcgctcga ccgctccggc acacaagggc cgccgctctc
    10561 ggtggacgcc gtgctggcgc tgcgccgcca ctcgatcggc gtgcagccgt gcctggacct
    10621 gaacgagcgc ttcggcggct acgccctccc cgccgcgctg cacggcggcc atccgctggc
    10681 ccggatgcgg gaggccacgg acgacgtcgt cgtcttcacc aacgacatcg cctccctgga
    10741 caaggagctg gccgccgggg acctccacaa caccgtcatc gtccgccacc agtgccacgg
    10801 cggcaccctg gaggacgcgg tcgagcacat cgcgggcctc gccaacgcgc gctaccgctg
    10861 gttcgagcag accgcggacc ggctgccccg gctgctcgcc gacgcgggtg cggggacgga
    10921 tctgcgccgg gacgtggacc actacgtgga cgggatgcgt gacgtgatgt gcggcaacct
    10981 gggctggtcc ctgcggacgg cccgctacga cgagcggggc atagcggcgg tcagcgacgg
    11041 ccgccaacga ccgtgggccg gactcagcgc ccccggttcc ggctgaccgg atccgctacg
    11101 tacgaacggc ccgccgcggc gggccgttcg ggtatcaagg ggcatgtgaa cgacaccctc
    11161 aacctgtgga aggcggggct cgccgaggcc cccgacgcca tctggcagca caccggtctg
    11221 cgcgtgctga tcctcgccga caacgcactc acccgcctcc cgcctgccct cggacggctg
    11281 ctgcggctgc acaccctgga cctcggccac aaccggctcg ccgggatccc ggaggagatc
    11341 ggcgagctgt cggggctgac ccgctgcctc tatctgcacg acaaccggct cccccggctg
    11401 ccgcgttccc tcgggcggct cgaccggctg ggctacctca acgtcggcga gaacccgctc
    11461 gggggtctgc cggaggaact cggcggcatg gcggggctgg tggagctgcg cgcgcagcac
    11521 gccgaactga ccgcgctgcc cggctcgatc gggcagctca gcgcgctgcg ggagctgtgg
    11581 ctgcgcggca accggatcac cgccctgccc gccggggtgt ccgcgctccg cgcgctgcgc
    11641 cagctggagc tgcgggagaa cgcgctgagc gaggtgcccg agccgctgcg cgggctcccg
    11701 cgcctgcgcc acctcgatct gcgcggcaac cggatccgga cgctccccga ctgggtcgcg
    11761 gagctgcccg ccctggagaa gctcgacctg cgctggaacc cgctcgacga gggcgtcgac
    11821 gacggcccgg tcgtccgggc gctcggcgag cggggctgcg tcgtgctcgg atgaggccgg
    11881 ggccgcgccg cgccgaagcc cggacgaggc gtcaggtcag gacgccgagg cccggacgag
    11941 gcgtcacgtc aggtcgaact cgccctcgcg cgcgcccagg acgaaggcgc gccactcggc
    12001 cggggtgaag atcagggccg ggccttcggg acggcggccg tggcgcatcg cgatgaagcc
    12061 ctcgacgaag gcgatctcga catcgcccac cccctggctg ctcgactgcc actgggcgct
    12121 tgtgaggtcg aggtcgggct tctcgccatt gcccctgagc ggctgtgcgg tcgtggtggt
    12181 gtctgccacg tgcggctcct cccggatcgt cgtcccggcc ccaccctagc gatcgcggcc
    12241 ggtgccggac aggccacgaa aggaggacgt gatctgtccg gcgggtgtcg tccgggtgca
    12301 tgcctcatgt ggacggaggg gccgccccga ccacccacat ggcgaagaac tgcgaacccc
    12361 cgccgtaggc gtgaccgagc gccgtgcgca ccccctcgac ctggtgctcg cccgcccggc
    12421 cgcggacctg gagggcggct tcggcgaagc ggagcatccc ggaggcgccg atcgggttgg
    12481 tggacagcac cccgcccgag gggttgacgg ggaggtcgcc gccgatctcg gtcaccccgg
    12541 actcggtgag cttccagccc tcgccctccg ccgcgaagcc caggttctcc agccacatcg
    12601 gctcgtacca gctgaacggc acgtacatct cgatcgcgtc gatctcccgg cgcgggtcgg
    12661 tgatcccggc ctgccggtag acgtcggcgg cgcagtcgcg cccggcgcgc ggcgagacgc
    12721 agtccttgcc cgcgaagagc gtgggctcgc tgcgcatcgc gccgccgtgc atccaggcgg
    12781 gcggccgggg ggcgcgggag gcaccggtgc ggtcggtgag caccatggcg cacgcgccgt
    12841 cggaggaggg gcaggtctcg gagtagcgga tggggtccca cagcatcggc gaggactgca
    12901 ccttctccag cgtcagatcc tgttcgtgga gatgggcgta ggggttgagc agggcgttgc
    12961 ggcggtcctt gtacgcgacg agcgcgccga tcgccggggg cgcgcccgtg cgccgcatgt
    13021 acgcgcggac gtgcggcgcg aagaatccgc ccgccccggc cagcagcggc tgctggaagg
    13081 ggacgggcag cgagagcccc cacatggcgt tggactcgga ctgcttctcg aacgccaggg
    13141 tgagcacggt gcggtggacg cgggcggcga ccaggttggc ggcgacgagc gcggtggagc
    13201 cgccgaccga tccggcggtg tgcacgcgca gcatgggctt gccgaccgcg ccgagcgcgt
    13261 cggcgaggta cagctcgggc atcatgacgc cctcgaagaa gtcgggcgcc ttgccgatga
    13321 ccacggcgtc gatgtccgcc caggtcagct cggcgtcctc cagggcccgt acggcggcct
    13381 cccggaccag tccggcgatc gagacgtcgc gccgggcggc ggtgtgcttg gtctggccga
    13441 ttcctacgac ggccaccggt tccttgctca ctggacggct caccgggctt ccccttccag
    13501 gacggcgacc aggttctgct ggaggcaggg gccggaggtg gcgtgggcca gcgcccggtc
    13561 ggcgtcgccg cggtggaggg cggcggcggc ctcgccgagc cggatgagcc cggcggccat
    13621 catggggttc gcggccggtg ccccgccgga cgggttgagg cgtacaccgt cgtccagctc
    13681 cagttcgcgg cgcaggatga tctcctgcga ggtgaacggg gcgtggagtt cggcgaggtc
    13741 gacgggcgcc tcgaaggccc cggcgcgggt cgcggcgagc cgggtcgacg gggagcgggt
    13801 gaggtcccgg acgcccaggc cgtgcggttc gatgcggtgg tccatgccgc ggatccacgc
    13861 ggggcgggcg cacagccgcc gcgcggtgtc cccggcggcg agcaccacgg cggccgcgcc
    13921 gtcgccgatg ggcgggcagt cgtggcggcg cagcgggcgc accaggtacg gggcgtcgag
    13981 gagggcgccg ggcggggcgg agcgggtcac ctgggcgtgc cggttgtccg cggcggcgtt
    14041 gcggccgcgc gcggcgacct cggcgagggc gcgttcgtcg gtgtcgcccg cgtcgatgag
    14101 cgcctgggcc tggagggcgg cgagggagac cgagtcgggc cacaaggggg cgacgtagta
    14161 cgggtcgagc tggcgggtga ggacctcggg cagatcgccg ggcgaggact ttccgtagga
    14221 gtagacgagc gcggtgtccg cctcgccggt cagcagcttg acccaggctt cgtagagcgc
    14281 ccaggcgccg tccatctcga cgtgggactc ggcgatgggc ggccaggcgc cgacgccgtc
    14341 gagcgccatg gtgaaggaga aggcgcggcc cgcgaggtag tcggaggagc cggagcaggt
    14401 gaagtcgatc tcgcccgccc tcaagcccac cgcgccgagc acctggtgga ggacgggcat
    14461 cagcatctcg acctcggaga cctccgcgct ggtgcgccgg gtgccgctct gcccgaaggc
    14521 gacgatggcg acgtctcgca tctacaacag ctccttgtag gtgtcgtagt cggcgtcggg
    14581 ttcgccggtg ggccggtagt ggtcggggta gcggccgccc tcggtccata cgggcgtcac
    14641 ccgcagtccc atgcgcacct ggtcgtacgg gatgccgccg atgcggccgt gcagggcgag
    14701 atcggcaccg tcgagggcga tgtgcgcgta gacgtacggc acttcgatat ccagattgcg
    14761 ggccttgatg ttcacgatgc agaaagtggt gacggtgccg cccgggccca cctcgacctg
    14821 ttcctcggtg gcgacgccgc aggtggggca ggcgccgcgg ggcggtacgt acaccttgcg
    14881 gcaggacggg cagcgttcgc cgacggtctt ccgcccggcg agggcggcga ggtagcggga
    14941 ctgggcgcgg ccgggcgcgt aggtgtagtc gagacgggcg ggggcgacga tgccggtgac
    15001 ggggtcggcg aacaccccgt cgtgggggcc gggttcatga gtggccgggc cgtcgtacgg
    15061 ttcgaagcag gcgatgtcgg tgatggagcc ctcgcgctcc tcggcccagc ggacccgtac
    15121 ccgcatgccg gtgcgcacgg cgtccggccc cggcgcgtcg agggcgtgca gcagggcggt
    15181 gtcggcgccg tcgagccgta ccagcgccca ggcgaagggg gtggacaggg gctggccgcg
    15241 gcgcggggcc gggttccagg cccaggtggt gacggtgccg gtgggggcga cctcgaccag
    15301 gtcgcgcagt tcggcggcgg tgtccgggtc gtattcgacg ggcgggacga gcacccggcc
    15361 accggcggtc cgtacgccga gcacggtgcg ctcgcgcagg cccgtgagga aggcgctctg
    15421 gacggggccg agggagcggg tgaaggggaa ctcgaccacg agaggggcct tcagcacctc
    15481 gggggcggga gccggtgtca tggggcgtct ccttctgctg gcagcggggc cctaggcccg
    15541 gcggtagacc ggggggcgtt tctccgcgaa ggccttcgat ccctctttgg cgtcggcggt
    15601 gtcgaagatg ggccagccgc gctcgagttc ggacgcgagg ccatcggttt cggtcatctc
    15661 ggcggtctcg tagacggatg ccttgaccgc ctcgacggcg agcgggccgt tggcgttgat
    15721 gagttcggcg atctccaggg ccttcttcag cgcggtgccg tcgtccacca cctggccgat
    15781 cagcccgatc cgctcggcct ccccggcggc gtacgggcgg ccggtgagca gcatctccag
    15841 ggcgtgggtg cgcggcacct ggcgggccag ccggaccgtg gagccgccga tggggaagag
    15901 cccgcgccgg acctcgtaca gcccgaaggt ggcgccgcgg cccgccaccc ggatgtcggt
    15961 gccctggagg atctcggtgc cgcccgccac gcagtggccc tcgacggcgg cgatcaccgg
    16021 tttgcgcggc cggtggtggc ggagcatggc cttccagtgg aggtcggggt cggccttcag
    16081 ccggtcccgg tagtgctgcc cctccatccg gccgccgccc gcgagcgcct tgaggtccat
    16141 cccggcgcag aagacaccgc cggcgccggt gagcacgacg gaccggacgg tgtcgtcctc
    16201 gtcggcctcg atccagccgt cgtacagccc gaccagcatg ggcaacgaga gcgcgttctt
    16261 ggcctcaggc cggttgagcg tcagcaccag cgtggcgcct atgcgctcga cgatgaggtg
    16321 ttcggtcccg tgcggcacag cagtcctccc gtctcagacc tagaacaggt tgcaggagcg
    16381 gcggagcgac ttcaatagga atctgatggg cagtcagatt ttttggccgc ggcccttccc
    16441 acctctcccc cgcggtgctg tcatgagcgc cgagcccgcc cgatgtcagg tcaggaggag
    16501 ccgtggagta caaccttgcc gacctgttcg agtcgatcgt ggacacggtg cccgacagag
    16561 aagcgctggt gtacgccgac catccgggca ccggcgccga gcggcggctg agctacgccc
    16621 agctggacgc cgccgccaac cggctcgccc accacctgag gaacagcggg gtcgcaccgg
    16681 gcgagcatgt ggggctgcac ctgttcaacg gtgtcgagta cctccagacc gtcctggcct
    16741 gcctgaagat ccgggccgtc ccggtgaacg tcaactaccg ctatgtggaa gacgagctgg
    16801 tctatctcta ccgcgatgcc gatctgaccg ccctggtcta cgacgccgag ttcggcgacc
    16861 gggtggccgc cgcgctgccg cgtacggaca ccctgcgcca cctggtccag gtgggcgccg
    16921 gggagggcgc gcccggcgcc gtcccgttcg ccgaggccga ggcgtcgggc gcggccgggc
    16981 gcggcttcgc gccccgctcc gcggacgacc gcttcatcat ctacaccggc ggcaccaccg
    17041 gcatgcccaa gggcgtgatg tggcggcagg aggacctctt cttctccggg ctcggcggcg
    17101 gcgcgccgac cggcgttccg gtcggccgcc ccgaggagct ggccgaacgg gtggcggcct
    17161 ccggcgacgg cctggtcttc ttccccaccg caccgctgat gcacggcacc tcgaccctca
    17221 cgaccttcat cggcctcaac ttcggtcaga aggtggtcct ccaccggaag ttcgtgcccg
    17281 aggaggtgct gaggacgatc gaaaaggaga aggtcagtac cgtgtccctg gtcggggacg
    17341 cgatgctgcg gcccctggtg gacgccctca ccggaccgct gaaggacatc gacctctccc
    17401 cgctgctcag cgtcagcagc tccggggcga tcctctcgga caccgtgcgc gcccagttcg
    17461 ccgcgctcgc gccgcacacc ctgatgctca acaacttcgg ctcatcggag tccgggttca
    17521 acggcaccgc caccgaggac tccggccccg agcggggctt ccgcgtgcgt gtcaacgacc
    17581 gtacggccgt cgtcgacccg gcgacccacc gtcccgtcgc gcccggggaa ccgggccggg
    17641 tcgcccagcg cggccatgtg ccgctcggct actacaacga cccgaagaag acggccgaga
    17701 ccttcttcga ggcggacggc gaacgctggg tgctcctcgg cgacatggcg acggtcgacg
    17761 aggacggcgt gatcacggtc ctcggccggg gttcccagtg catcaacacc ggtggcgaga
    17821 aggtgtaccc ggaggaggtc gaacaggccc tgaaggccca tccggacgtg tacgacgcgc
    17881 tggtggcggg cgtccccgac gagcgctggg gcaatcgcgt ggcggccgtc gtccagccgc
    17941 gggagggggc cgatgccctc accgccgacg cggtgcggga ccactgccgc acccggctcg
    18001 ccgggtacaa gatcccccgt accgtcgtct tcaccgaccg catccagcgc tcccccagcg
    18061 gcaaggccga ctaccgctgg gcccgcacgg tcgcggccgg agacggcacc ggggcgtagc
    18121 ggcccgcgac cctatcgagt ggtcaggacg cgggcggcga agtcgcggac cgcgtccagg
    18181 acgcccgtgc cgctgtgtcc gacccccggc acgatgtcga gggtgacgtc gatcccgagc
    18241 gcgacgtagt tgtcgcgcag tgcggtgatc cgctcgaccc gggtccggcc cagggcgtcg
    18301 gcgccgtcca tccagttgga gtcgcccggg ttgttgatct cccaggtctc ggtgtcctcg
    18361 gcgccgacca ccatgtggac cgccacctta cggatctcct ccagccgcac cggcgcaccg
    18421 aagcgctcct cgaaaccggc cgtgcccagc caccattcac ggtccgggtc gatcagcgtg
    18481 acccggcccg gcgcgccgat cgacacggcg cacagccgct ccgggtggag gtagaggaag
    18541 cggtgggcga actgcccgcc gcccgagaag ccctggagca tgaaccggtc ggtgtcgacg
    18601 gtgaagcgcg tcccgacctc gtcgacgatc gccagcagct cccggtcgta gcggatgccg
    18661 tcgtactcga tgaacttgaa gttgtgcagg tcgtccgggt cgccgatggc cgcggggaac
    18721 agcggggtga ggatgacgac gccgtgccgc tcggagaact ccgccatcgc gttccggtac
    18781 tcggccgccg tgcggccggt gccgtgctgg atcaccagca gcgggagcgg tgtggtggtg
    18841 gtctcgtgca cggagggcac gtgcaggctg taggagaacc gctgatcgtg ctgtgaggcg
    18901 aagaaggtgg tggcgccggt gcggtagaac gccttggtgg tcttgatgcg cggtgtcaca
    18961 tgtcctcctg cgatgcgccg ccaccgacat ggggcggtgc ccgtcacgat cacgggtgcg
    19021 tcggcggcgg ctcaagatga ttgccgcgca ggcgtcaatg accgggacgg tgtcagcggc
    19081 gcagtgcgga gagcagatcg acgccgaggg tgcggacggc ttcctcgtcc agctggtaat
    19141 gcacccgggc gccctgccgg tgggtgtgca ccattccggc ctcccggagt ttgcgcagat
    19201 ggcgcgacat ctgcggcggg gtggtgtcga agtggctggc cagctcggtc gtcgtcatcg
    19261 actgccgcag caggacgcgg cacacccgga cgcgcagggg ctcgtccagc gcccgcaccc
    19321 ggcgcagcac ctcgtccatg gcgggcggct ccccgtcgcc gtctccccgc accgggtact
    19381 gcacgaccac cggatagccg gggtagtgct tgatcgccac atgcgggttg atgtgccgcg
    19441 agggcaccag caggcacggg acgtcggcga ggctggcccg accgttgtac agcttgtcga
    19501 agacgacccg cggcggatcg tcctcgaccc gggcggtggg gaagtcggcg agcgcccggg
    19561 cgccgtccag ccggtgcttc tggaagcgca tacggacgtc cgcctccagt gcgcggcgca
    19621 gccgggccca ctccccctcg aacagctcgt cggcggcggc gtgcaggaag tcggtgaggt
    19681 cctcccggaa cgcggcgggc ccggcgagca gccgcactcc cagcgcgaac cggccgtccg
    19741 acatctgccg cagcctgccg aggaagcgtt cgggggtgtt gcccgggaca ccggtcggct
    19801 ggtggctgtt ctggccgatc agggcctgtt cggtcatggc cgtgaacgtc gcctcgggca
    19861 gctcgccgat gtcggccagc tcctcctcca gggagcgctc gggcccggga gtgaggggca
    19921 gcagatagcg ggcgcggaac gcgccccaca gcggtgccca ctgcgcggcc cgcgccagca
    19981 gccgctcgtc cgcgccctgg agcacggcgc cgacccagcg gcggctggcc ggatggtgcc
    20041 ggggctcgtc cagcgcgtgc aggcaggcgc acagctcggc gagcggggac agccgtccgg
    20101 cgatgcgctc ctcgggagcg gggcccaggt cgatcactac gggcatgcgt cgacggtccg
    20161 ggattgacgc cttgctgtca atcgtcttgt ggccggttcg cgaggggcgc aggctccggt
    20221 catcttcccg gccgcccccg atcccgcccc cgatttccgc acctctccgc gacggagcgt
    20281 ttccatgccc cctctcctcc ggaacggtcc gcgcgtcgtg ctgaccgtca ccctgctggc
    20341 cacggtgagc agcgcgtgca ccatcggttc cgccgacgac tccaccgcgg ccgccggcta
    20401 cccctcccgc ggcctgtcca tcctggcccc cggcagcgtc ggcggcggct gggacgcccg
    20461 ggcccgcggc atgagcgccg cgctcaccgg ctgcaagatc atcgacgagg acgtcacggt
    20521 caccaacaag ccgggcgcgg gcggagccat cgggctcgcc cggatggtcg gccgcagcgg
    20581 cgacccgtac cagctgatga ccatggacac ggtcaccatg gccgggggcg cggtgcagaa
    20641 cgactccccg gtcggcctct cgtctctcac ccccatcgcc gggctgaccg tcagccccag
    20701 cgtgatcgtg gtgcccgccc gctccccgta ccgcgatctg acgtcggtga tggcggccat
    20761 gaagcggaac cccaagggca tgtcctgggt gggcggttcc ctgggcggcc ccgaccacat
    20821 caccgtcgcc tccctcgcca aggcccgggg catccccgtc aagaagatca cctacgtgcc
    20881 gaccggcggg ggcggcgaag tgctcaacct gctgctgagc ggggcgtcca aggtcggcat
    20941 gtcgacactg accgagatcc gcccgcagat cgaggcgggc aagctccggg tcctcgcgat
    21001 cagcggcgac gagcgtcccg aggggctgaa cgccccgacc ctcaaggacc tcggatacgg
    21061 cggatcgagc gtggtgagca ccggcg
//
