LOCUS NZ_GG657754 21033 bp DNA linear CON 01-MAY-2024 DEFINITION Streptomyces himastatinicus ATCC 53653 supercont1.1, whole genome shotgun sequence. ACCESSION NZ_GG657754 VERSION NZ_GG657754.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces himastatinicus ATCC 53653 ORGANISM Streptomyces himastatinicus ATCC 53653 Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group. REFERENCE 1 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D., Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Annotation of Streptomyces hygroscopicus strain ATCC 53653 JOURNAL Unpublished REFERENCE 2 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA REFERENCE 3 (bases 1 to 10901646) AUTHORS Fischbach,M., Godfrey,P., Ward,D., Young,S., Kodira,C.D., Zeng,Q., Koehrsen,M., Alvarado,L., Berlin,A.M., Borenstein,D., Chen,Z., Engels,R., Freedman,E., Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heiman,D.I., Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T., Park,D., Pearson,M., Roberts,A., Saif,S., Shea,T.D., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Walk,T., White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Galagan,J., Nusbaum,C. and Birren,B. CONSRTM The Broad Institute Genome Sequencing Platform, Broad Institute Microbial Sequencing Center TITLE Direct Submission JOURNAL Submitted (09-FEB-2009) Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA 02142, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: Arachne v. April 2007 Genome Coverage :: 6x Sequencing Technology :: ABI ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_000158915.1-RS_2024_05_01 Annotation Date :: 05/01/2024 03:02:38 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.7 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 9,680 CDSs (total) :: 9,608 Genes (coding) :: 8,720 CDSs (with protein) :: 8,720 Genes (RNA) :: 72 rRNAs :: 4, 1 (5S, 16S) complete rRNAs :: 4, 1 (5S, 16S) tRNAs :: 64 ncRNAs :: 3 Pseudo Genes (total) :: 888 CDSs (without protein) :: 888 Pseudo Genes (ambiguous residues) :: 0 of 888 Pseudo Genes (frameshifted) :: 423 of 888 Pseudo Genes (incomplete) :: 530 of 888 Pseudo Genes (internal stop) :: 36 of 888 Pseudo Genes (multiple problems) :: 97 of 888 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 20:01:42 NOTE :: This is a single region extracted from a larger record! Orig. start :: 1312806 Orig. end :: >1333839 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to GG657754.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation was added to the scaffolds in August 2010. FEATURES Location/Qualifiers region 1..>21033 /candidate_cluster_numbers="1" /contig_edge="False" /product="terpene" /region_number="9" /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /tool="antismash" cand_cluster 1..>21033 /candidate_cluster_number="1" /contig_edge="False" /detection_rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /kind="single" /product="terpene" /protoclusters="1" /tool="antismash" protocluster 1..>21033 /aStool="rule-based-clusters" /category="terpene" /contig_edge="False" /core_location="[10000:>11033](+)" /cutoff="20000" /detection_rule="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /neighbourhood="10000" /product="terpene" /protocluster_number="1" /tool="antismash" proto_core 10001..>11033 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)" /neighbourhood="10000" /product="terpene" /protocluster_number="1" gene complement(648..1301) /locus_tag="SSOG_RS04900" /old_locus_tag="SSOG_00994" CDS complement(648..1301) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1057: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014057656.1" /locus_tag="SSOG_RS04900" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_00994" /product="TetR family transcriptional regulator" /protein_id="WP_039940647.1" /transl_table=11 /translation="MTARTRQQERVGATREALLTAAERLFAEHGVHAVANRQISAAAGQ GNNAAVNYHFGTKTDLVRAIVRRHAEQMERIRAGMLADIGDSTELRDWVACVVRPTTEH LAALGRPSWYARFIAQVTADPALQAVTTAEAFAAAPSLHPLQDGVNRCLPDLPDEVYAE RGAMTRHLITQMTAERERALADAAPTSRTTWHDTATGLIDAIVALWQAPVTPEG" gene complement(1435..2910) /locus_tag="SSOG_RS04905" /old_locus_tag="SSOG_00995" CDS complement(1435..2910) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006381137.1" /locus_tag="SSOG_RS04905" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_00995" /product="DUF1996 domain-containing protein" /protein_id="WP_009713105.1" /transl_table=11 /translation="MRRNTRRRSKVARRAIVATAALALGAGGLVTVNMYASADAGDSQQ SDTRGRELSARASTIDCPDVGQRLSAVPQRARAEVDRELALLDKQVAEAYQRLAGSQRA IQQDANFAQNAIMGPLKDKRTAAIDRISIAIGRVAATPQGLDGLATCTLKASGNQPGGG QGGNQGGGQGENQGGNQGGNQGQTGNGPVAADFVDITGVQPNARTPRPARGASKGLFTT KCGVNANKLYNTDNVIVAPGVSNGAHHTHDYVGNQANNAFADNNAFARGRTTCQNQGDK STYYWPVLRLQDGTREFDADRQGGGAEGNTGRILTAKKVTLEYAGNPRGKVVAMPRFLR IITGDAKAFSNGTANANASWSCTGFENRQLKDKYPICPQGSDVVRTSKFQSCWDGKNAD SANHRSHVAFTDADGRCPKGFVAIPQLVQRLVYDVDAPSLKDNGKTRPFFAVDGFPEQL HKPVTDHGDFINVFDERVMKQMVRCINSGRTCR" misc_feature complement(2752..2754) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gene complement(2986..3492) /locus_tag="SSOG_RS04910" /old_locus_tag="SSOG_00996" CDS complement(2986..3492) /GO_function="GO:0010181 - FMN binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1160: flavin reductase domain protein FMN-binding" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009084171.1" /locus_tag="SSOG_RS04910" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_00996" /product="flavin reductase" /protein_id="WP_245606224.1" /transl_table=11 /translation="MTPSQADFREAMAHLPAAVNILTTDGPNGRCGITVSAVCSVTDDP PTVLVCVNRRSAMHDVFRANGRVCVNVLGGAQQDLALHFAGATKVAMAERFTWDIWDRT QEVPVLKDALVTAIGTITDAVPMGTHSVLFATIDRITTRAGGQSLVWFNRAFHRLAAGN DGSVT" gene complement(3525..4280) /locus_tag="SSOG_RS04915" /old_locus_tag="SSOG_00997" CDS complement(3525..4280) /NRPS_PKS="Domain: PKS_KR (8-183). E-value: 3.9e-12. Score: 38.4. Matches aSDomain: nrpspksdomains_SSOG_RS04915_PKS_KR.1" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1001: short-chain dehydrogenase/reductase SDR" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020553851.1" /locus_tag="SSOG_RS04915" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_00997" /product="SDR family NAD(P)-dependent oxidoreductase" /protein_id="WP_039936590.1" /transl_table=11 /translation="MTTTTPDRVALVTGAARGLGACIAGRLYGAGYRVALTDLDEAAAV AAAADLAPDGRNAIGLGLDVRDKDAFVRVRDQLVARWGAVHVLVNNAGYSKVEPLMEIT PDSFGSVVSSNLDGTFFGCQVFGAYFAGRGYGRIVNIASLAGQNGGSATGGHYAAAKGG VATLTKVFARELGPQGVTVNAIAPGVQDLPVVRELVAPEQLARIEESIPVRRLGRPEFI ADMAVLLAADHADTVTGACWDANGGLNMR" aSDomain complement(3732..4256) /aSDomain="PKS_KR" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_SSOG_RS04915_PKS_KR.1" /evalue="3.90E-12" /label="SSOG_RS04915_PKS_KR.1" /locus_tag="SSOG_RS04915" /protein_end="183" /protein_start="8" /score="38.4" /specificity="KR activity: inactive" /specificity="KR stereochemistry: C2" /tool="antismash" /translation="VALVTGAARGLGACIAGRLYGAGYRVALTDLDEAAAVAAAADLAP DGRNAIGLGLDVRDKDAFVRVRDQLVARWGAVHVLVNNAGYSKVEPLMEITPDSFGSVV SSNLDGTFFGCQVFGAYFAGRGYGRIVNIASLAGQNGGSATGGHYAAAKGGVATLTKVF ARELGPQGVTVN" CDS_motif complement(4197..4250) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_SSOG_RS04915_0001" /evalue="6.30E-02" /label="PKSI-KR_m1" /locus_tag="SSOG_RS04915" /protein_end="28" /protein_start="10" /score="6.0" /tool="antismash" /translation="LVTGAARGLGACIAGRLY" gene complement(4689..4961) /locus_tag="SSOG_RS57380" CDS complement(4689..4961) /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF019640.4" /locus_tag="SSOG_RS57380" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="hypothetical protein" /protein_id="WP_281048186.1" /transl_table=11 /translation="MGDGGGGRATRPDRQTGLLRLAAAHLAKTSFEVVRAAYQLGGIAA IADDSPMQRYLRDASVVPQHAFLQEGMYDGAGAVLMGVQPFPGFL" gene complement(<4994..5911) /locus_tag="SSOG_RS04925" /old_locus_tag="SSOG_00999" /pseudo="" CDS complement(<4994..5911) /GO_function="GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]" /GO_function="GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_N" /gene_functions="biosynthetic-additional (smcogs) SMCOG1191: acyl-CoA dehydrogenase type 2" /gene_kind="biosynthetic-additional" /inference="COORDINATES: protein motif:HMM:NF014790.4" /locus_tag="SSOG_RS04925" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_00999" /product="acyl-CoA dehydrogenase family protein" /pseudo="" /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-05, bitscore: 24.7, seeds: 790, tool: rule-based-clusters)" /transl_table=11 /translation="MADGPLAGVASSSGGGGNRRATRGASPMTQATPITRSPDPIDDVL TVVAERQPEFEEKRHIPRDVIEVFKRAGLYRASTPKRFGGDPLPPARFLALIERISAVD GSAGWVASFGSSLVYLAALPLETQAELYADGPDVVFAGGLFPVQPAERVEGGYRVRGRW RFASGCTGADVLGVGIKAGEDATGRPLTAVLRPGQVRIADNWNVVGMRGTGSHDLVVDG AVVPEEWTFVRGGEPTVDEPLYRYPTVPYAAQVLAVVGLGVARAALDQAIAAGGRAGYT GAPRPADRATYRIAVGQAEAQLRSA" gene complement(5946..7364) /locus_tag="SSOG_RS04930" /old_locus_tag="SSOG_01000" CDS complement(5946..7364) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1003: sensor histidine kinase" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014182268.1" /locus_tag="SSOG_RS04930" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01000" /product="ATP-binding protein" /protein_id="WP_039936592.1" /transl_table=11 /translation="MSSPVEPADFRVLMQSLKYCVLLHDARTYEILWANRAACDLLGWS VDELKPLKAPDMSKNARQYSRELGHRWLGRAVEDGVSATEWCYRSKTGEETLTEAIAIR VDLPGRTAVMVQFRDIAEEKAVRRDLCRTESRLRTFLGSLAEGIVVLDDGDRVVFASES AVRLLGDGLRGADFADYCHDGPVPTAGEGRYRFAAPGDGPRWYASTCQHIEIESDLRGR MLLFYDITDRVRAEEEHRRETQHLDHLARYNAMGDMAMAIAHEVSQPLAAAYNFVEGAR GRLATDDTSVAFGLDNAARQIERARRILGSLRSYVGRLEPSERLTDLGAIVRDCAYFIE LRAQEHSVAVALDLTAEPLPVRCENVLIGQVVMNLAFNAVDEMARCPLAERRVRIATRL MADGDAELTVTDWGNGLPPGDRIFDGVFTSKENGSGIGLALSHRIITRHGGRIDATPNQ PHGAVFRFTLPAGV" gene complement(7375..8013) /locus_tag="SSOG_RS04935" /old_locus_tag="SSOG_01001" CDS complement(7375..8013) /GO_process="GO:0000160 - phosphorelay signal transduction system [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family DNA-binding response regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019063425.1" /locus_tag="SSOG_RS04935" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01001" /product="response regulator" /protein_id="WP_009713111.1" /transl_table=11 /translation="MSGDATTDTLVYILDDDEELSDSLAWLLESVGIRSERFRDARAFL RSYDRARPACLILDVRMPELSGFDVQQLLNETGAPLPVVFVSAHGDIRMSVRAMQNGAV DFLEKPYDPQHMLDVVQAALRTARERFERAAVECELRAKLDSLTSREREVLGLAVDGMA NKQIAARLGISAKTIDVHRARIREKTGAQSMATLVRDVLRLGLRPAADR" gene complement(8125..8616) /locus_tag="SSOG_RS04940" /old_locus_tag="SSOG_01002" CDS complement(8125..8616) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010982215.1" /locus_tag="SSOG_RS04940" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01002" /product="FBP domain-containing protein" /protein_id="WP_009713112.1" /transl_table=11 /translation="MKPLTEQEIRSAFVNCTKGEAKRLSVPRDLAAKPWDDLDYLGWRD PQAYDRAYLVTLLDDRPRALALRCPTPASWQTQRGMCSLCLTSPADGVSLMVAPKAGKA RQQGNSVGTYICSDLACSLYVRGKKDAGAGARLHESLTLEEKIERTTANVAAFLAKVTA " gene 8688..9257 /locus_tag="SSOG_RS04945" /old_locus_tag="SSOG_01003" CDS 8688..9257 /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1239: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017567346.1" /locus_tag="SSOG_RS04945" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01003" /product="TetR/AcrR family transcriptional regulator" /protein_id="WP_009713113.1" /transl_table=11 /translation="MAYAGLTAERLTRAGAELADEVGFDQVTVSELARRFDVKVASLYS HLKNSRDLKTRIALLALEELADRAAEALAGRAGKDALTAFGNVYRDYAREHPGRYAAAQ FRLDPEAAAASAGGRHSQMTRAILRGYDLTEPDQTHAVRLLGSVFHGFVSLELAGGFSH SAPDSAESWSRTLDALDALLRNWPTP" misc_feature 9398..9411 /note="TFBS match to BldD, Development and antibiotic global regulator, confidence: weak, score: 19.06" /tool="antismash" gene 9504..9986 /locus_tag="SSOG_RS04950" /old_locus_tag="SSOG_01004" CDS 9504..9986 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_013005448.1" /locus_tag="SSOG_RS04950" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01004" /product="hypothetical protein" /protein_id="WP_039936593.1" /transl_table=11 /translation="MRYVPAGAGIGLVLCALALQGPAAAADDSELRISPKKSAPGSTVT VSTTACGSDVTYGKGTAGGDEFHLLDDGHKGTLTGTFRIPKGADSGSHEVIVKCPPSIK ITDTVKVKRSHPSGGVDAGFGPAAVGDNKPTLLGATVLAVTAGGVLVMRRHRSVRR" gene 10001..>11033 /locus_tag="SSOG_RS04955" /old_locus_tag="SSOG_01005" CDS 10001..>11033 /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) terpene: Lycopene_cycl" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019355430.1" /locus_tag="SSOG_RS04955" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01005" /product="lycopene cyclase family protein" /protein_id="WP_039936595.1" /sec_met_domain="Lycopene_cycl (E-value: 4.3e-80, bitscore: 268.7, seeds: 20, tool: rule-based-clusters)" /transl_table=11 /translation="MAWDAEVAVVGAGAAGLTLAHRLAALPSPPRVLLVGAPDGPLRAP ERTWCWWEEPGGEFDGALAARWSRVRVHGADGRPLDRELAPFVYKMLRSRDFEHWMAAR LDAAPSVRRVEAVVDEVRDDAGGALVRGACAGGRPVIWRARWAFDSRPAAALPPARTTL LQHFRGWFVRCDAPALDPAVAELMDFRTPQPRRGLSFGYVLPLSDREALVEYTEFSPAV LEDAAYDAALRHYTGAVLRLPPFRVLSTEQGVIPMTDGRFPRRAGAAVFRIGTAGGATR PATGYTFAAVRRQSHAVAAAFAAGRRPVPPAPYPARALAMDAAMLRALDTGRVAGAYVF TGLF" gap 11034..11279 /estimated_length=246 gene <11280..>12239 /locus_tag="SSOG_RS04960" CDS 11280..>12239 /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018888661.1" /locus_tag="SSOG_RS04960" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="FAD-dependent oxidoreductase" /protein_id="WP_154686080.1" /transl_table=11 /translation="MAGLAAATALAERGAAVVLYERRAMLGGRLAGWPTMLADGSAATM CRGFHAFFRQYYNLRGLLRRIDPALRMLTGLPDYPLWHGSGLRDGFAGVPRTPPWSALG FVARSPSFGWRDLAGLDPVAALPLFDVRLPWIHERLDALSAAEFLDAVRFPAAARHLAF EVFSRSFFTDPGELSAAELAVMFHIYFLGSSEGLLFDVVREPFPYALWDPLRRYLEGHG AQVRPGAAVESVRPLDGGRVAVDGEAYDGVVLALDTAGLRTLVANSPGLGDPGWRERIA ALRTAPPFLVSRLWLGAPVDPGRPGFLGTSGYGPLDNVS" misc_feature 11487..11489 /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gap 12240..12564 /estimated_length=325 gene <12565..12750 /locus_tag="SSOG_RS04965" /old_locus_tag="SSOG_01006" /pseudo="" CDS <12565..12750 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010639531.1" /locus_tag="SSOG_RS04965" /note="incomplete; too short partial abutting assembly gap; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01006" /product="isorenieratene synthase" /pseudo="" /transl_table=11 /translation="LVRTDLPVALMERAATSGFLAANALLARWGVSGQRLWTVPRHGRT AVLRGVHRLAGKRHRP" gene complement(12768..13727) /locus_tag="SSOG_RS04970" /old_locus_tag="SSOG_01007" CDS complement(12768..13727) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019525633.1" /locus_tag="SSOG_RS04970" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01007" /product="DUF5914 domain-containing protein" /protein_id="WP_009713117.1" /transl_table=11 /translation="MSLRRRGVPWDRQRSTWREARPALIAAALKRAQDRPSGNWYVLGA SAAVAPGRPFGRTVAGTEVVAWRGPGGRLVAGPGACPHLGAPLKDAVVSRGTLLCHWHG LALPGDAATGWCPLPAHDDGVLAWVRLDAAGGEEPLERPVLPPRPVAGATLAAVHDVTG TCEPADVVANRLDPWHGGWLHPYSFVDLTVEEPDGDDGLAVRVSFKVAGRVVVPVRAVF SAPGPRTVVMRITDGEGRGSVVETHATPLTPENHGRPRTAVIEAVLATSDRPGFAVARA AAPLLRPLMRAAAGRLWRDDLAYAERRWALREAGRFPG" gap 13753..15851 /estimated_length=2099 gene complement(<15852..16230) /locus_tag="SSOG_RS04975" /old_locus_tag="SSOG_01008" CDS complement(<15852..16230) /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) DAO" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006607880.1" /locus_tag="SSOG_RS04975" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01008" /product="FAD-dependent oxidoreductase" /protein_id="WP_039936600.1" /sec_met_domain="DAO (E-value: 3.2e-09, bitscore: 35.9, seeds: 521, tool: rule-based-clusters)" /transl_table=11 /translation="MRTVAGPTDHVVVVGAGLSGLAATLHLLGAGRRVTVVERATRPGG RAGRLDRGGYRFDTGPTVLTMPDLLAEPLAAVGEELSDRLDLVALHPAYRAAFADGSSL DVHTGADAMEERGTGLRRAARS" CDS complement(16311..>16773) /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /codon_start=3 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003980892.1" /locus_tag="SSOG_RS04980" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01009" /product="alpha/beta hydrolase" /protein_id="WP_039936602.1" /transl_table=11 /translation="FDGPESRNYEAANRIVKCADGHAPAPRRVVADVRRMRHLDPHPVL TGIEASTCAYWHHRPARRTPLGGPDAPPGLLIASAHDPVTPIEGAHRLRHRLPGSRLVT LHQDYSHGVFASRGNACVDRTAAAYLVDGRLPAGDVHCTGPGLPVPGPRK" gene complement(16311..>16777) /locus_tag="SSOG_RS04980" /old_locus_tag="SSOG_01009" misc_feature complement(16750..16752) /note="tta leucine codon, possible target for bldA regulation" /tool="antismash" gap 16778..17765 /estimated_length=988 misc_feature 17909..17924 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: medium, score: 24.42" /tool="antismash" misc_feature 17909..17927 /note="TFBS match to FuR_variant_2, Ferric Uptake Regulator, confidence: weak, score: 21.94" /tool="antismash" misc_feature complement(17911..17925) /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 21.91" /tool="antismash" misc_feature 17912..17923 /note="TFBS match to CcpA, Catabolite control protein A, confidence: medium, score: 17.23" /tool="antismash" misc_feature complement(17912..17927) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 20.78" /tool="antismash" misc_feature 17915..17930 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 18.85" /tool="antismash" gene 18019..19275 /locus_tag="SSOG_RS04985" /old_locus_tag="SSOG_01010" CDS 18019..19275 /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) ATP-grasp_3" /gene_functions="biosynthetic-additional (smcogs) SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018105065.1" /locus_tag="SSOG_RS04985" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01010" /product="ATP-grasp domain-containing protein" /protein_id="WP_009713120.1" /sec_met_domain="ATP-grasp_3 (E-value: 1.7e-10, bitscore: 40.3, seeds: 15, tool: rule-based-clusters)" /transl_table=11 /translation="MAHLLMVESWVGSMSRLLPRAIRENGHEFTFLTRDLHHYLRSAPE GTAHPLLAARHVLTADTNDTATLLPAVERLHTALGFDGVITSCDYYLPVAARLADRLGL PGPSAEAVGNACRKDATRRVLDAAGVPGPRFAVHSTWAEVAEGAREIGYPLVVKPVDLC AGMYVRRVDDEAALRDAWRALDGFPVNARGQRRSPAVLLEELLDGPEVSVETVSYGGTT EVIGVTDKSVGGAPAFIETGHMFPAALASADAAAARETAVLALKALGLDDVVAHTEIKL TAAGPRVVEVNPRPAGNRITELIRHVTGVDLATACVDVALGHRPDLRGWDTGMRSAAIG FLVPATAGTLASVDGGDAAREAPDVLEVQLAEPGRSVEAAGSNNAYLGHVMAGDPEGPG ARARVEALLSGLRPRVVAP" gene 19272..20120 /locus_tag="SSOG_RS04990" /old_locus_tag="SSOG_01011" CDS 19272..20120 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018105064.1" /locus_tag="SSOG_RS04990" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="SSOG_01011" /product="DUF364 domain-containing protein" /protein_id="WP_039936604.1" /transl_table=11 /translation="MTARPLTAAPPCFSYEELADRVLDGAFGPDPRTQRIAVAFTTRQA VRHDGRSGGYRNEVLSLRLGEAVGSCAVEPGALPYEAIDTCVGVDVARLLRHELAPVRV AALDAYLLRMLPHTSASGARPQPLAAGTSLEKSRARAEAVTGLLGPGPGRTVLVVGVVN SLLESLRSRGLGYVACDLKGGTTEWGEPVATDALAQLDRCDAVLASGMTLGNGTFEPLR EHALRHGKPLVMFAQTGSAILPRFVGAGVTAVCAEPYPFFWLDGGPGLIHCYGGHYGGP A" ORIGIN 1 agcgaggaac tcgtccgcag gcagggcatc gcggacggat acgtccggcc cgtggcctgg 61 cggggcggcg agcagctcag cgtgtccagt gcgggcaacc gtgtccacgt cgccatcgcc 121 acctgggagt ggccgcggct cttcggggac gcgacccagg aggagggcat ccgcctcggc 181 acctcccgct ggcgccgccc ggcgcccgac accgcgccgg tgcacgccaa ggcggcgtcg 241 ctgtacaaca tctgcaccct cgcccgcgac gaggccgaag ccgccggtta cgacgacgcc 301 ctgctgctgg accaccgggg tctgctggcc gaggccaccg gtgccaacct cttcctcgtc 361 atcggcggtg ccctgcacac ccccgtcccc gacaccttcc tcaacggcat cacccgccag 421 accgtcatcg gcctcgccga cgacctcggc atcccggtcc atgagcgccc tctggagccg 481 gacgccctgg ccgacgccga cgaggtgttc ctcaccggca ccgcctacga ggtgcagccg 541 gtccgcgcgg tggacggcca ccggtaccgc gtcggcaagg tgacgtcggc gctggccgtg 601 gcgtacgccc gtctggtgcg cacgccctag cctggtggtc gcccgggtca cccctccggg 661 gtgaccgggg cctgccaaag ggccacgatc gcgtcgatga ggccggtggc ggtgtcgtgc 721 cacgtcgtac gggaggtggg ggcggcgtcc gcgagggcgc gctcccgctc ggcggtcatc 781 tgcgtgatga ggtggcgggt catggcgcca cgctccgcgt acacctcgtc gggcagatcg 841 ggcaggcagc ggttcacccc gtcctgcaac gggtgcagcg acggggcggc ggcgaacgcc 901 tccgcggtgg tgaccgcctg gagcgcgggg tcggccgtga cctgggcgat gaaccgcgcg 961 taccagctgg gccggcccag cgccgccagg tgttcggtgg tcggccggac cacgcaggcc 1021 acccagtccc gcagctcggt ggagtcgccg atatcggcga gcatccccgc gcggatccgc 1081 tccatctgct cggcgtgccg gcggacgatc gcgcggacca ggtcggtctt ggtgccgaag 1141 tggtagttga ccgcggcgtt gttgccctgt cccgcggccg cgctgatctg gcggttggcg 1201 accgcgtgca ccccgtgctc ggcgaacagc cgctccgccg ccgtcagcag cgcctcccgt 1261 gtcgcgccga cccgttcctg ctgcctcgtc ctggccgtca tcatcaccac cgcatcccgc 1321 tccgcacgca cccgctttaa atcaatccat ttaaagcata cccggtgtcg cgccgggcgg 1381 ccgtgcacgc cctgccggcg gagtggcgta cggccaccgg cagggcgctg tgcctcagcg 1441 gcaggtgcgt ccgctgttga tgcaccgcac catctgcttc atcacccgct cgtcgaagac 1501 gttgatgaag tccccgtggt cggtgaccgg cttgtgcagc tgctcgggga aaccgtccac 1561 cgcgaagaac ggccgggtct tcccgttgtc cttcaggctg ggcgcgtcca cgtcgtacac 1621 caggcgctgc accagctgcg gaatcgccac gaagcccttg gggcagcggc cgtcggcgtc 1681 cgtgaacgcc acgtgggagc ggtggttggc gctgtcggcg ttcttaccgt cccagcagct 1741 ctggaacttc gacgtacgca ccacatcgct gccctgcggg cagatcgggt acttgtcctt 1801 cagctgccgg ttctcgaacc cggtgcagct ccaggaggcg ttggcgttcg ccgtcccgtt 1861 gctgaacgcc ttcgcgtcgc cggtgatgat gcgcaggaac ctgggcatcg ccacgacctt 1921 gccgcgcggg ttgcccgcgt actccagggt gaccttcttg gccgtcagga tgcggccggt 1981 gttgccctcg gcgccaccgc cctgccggtc cgcgtcgaac tcccgggtgc cgtcctgaag 2041 gcgtagcacc ggccagtagt aggtcgattt gtcgccctgg ttctggcagg tggtgcggcc 2101 acgggcgaag gcgttgttgt cggcgaaggc gttgttggcc tggttgccga cgtagtcgtg 2161 ggtgtggtgt gccccgttgg acacgcccgg cgcgacgatg acgttgtcgg tgttgtagag 2221 cttgttggcg ttgacgccgc acttggtggt gaacaggccc ttggaggcgc cacgcgccgg 2281 gcgcggggtg cgcgcgttgg gctggacgcc ggtgatgtcc acgaagtccg cggccaccgg 2341 gccgttgccg gtctggccct ggttgccgcc ttgattgccg ccctggttct caccctggcc 2401 gccaccctgg ttgccgccct ggccaccgcc gggctgattg ccggatgcct tgagcgtgca 2461 ggtggcgagc ccgtccaggc cctgcggtgt ggcggccacc ctgccgatgg cgatcgagat 2521 ccggtcgatg gccgccgtgc gcttgtcctt cagcggaccc atgatcgcgt tctgtgcgaa 2581 gttggcatcc tgctggatcg cccgctggga accggccagc cgctggtacg cctcggccac 2641 ctgcttgtcc agcagggcca gctcccggtc cacctcggcc ctggcccgct gcggaaccgc 2701 gctcaggcgc tggccgacat cggggcagtc gatggtggag gctcgggcgg ataactcccg 2761 gccgcgggtg tcgctctgct gcgagtcgcc cgcgtcggcc gaggcgtaca tgttgaccgt 2821 caccagtccg cccgccccca gggccagtgc ggcagtggcg acgatcgccc gtctcgcaac 2881 cttcgaccgt ctacgcgtgt tgcgtcgcat ggaactcctt agtcatgtcg gacgcgttcg 2941 acggaagggt atagccatgc gaccgggccg gggcaccggg gtggatcacg tcaccgatcc 3001 gtcatttcct gccgcgagcc ggtggaacgc ccggttgaac cagaccaggc tctggccgcc 3061 cgcccgggtg gtgatgcggt cgatggtggc gaagaggacg ctgtgggtgc ccatcgggac 3121 cgcgtccgtg atggtgccga tcgcggtcac cagggcgtcc ttgaggaccg gcacctcctg 3181 ggtgcggtcc cagatgtccc aggtgaagcg ctctgccatc gccaccttcg tggcaccggc 3241 gaagtgcagt gcgagatcct gctgtgcgcc accgaggaca ttcacgcaga cccggccgtt 3301 ggcccggaac acgtcgtgca tggcgctgcg gcggttcacg cacaccagga cggtcggcgg 3361 gtcgtcggtg acggagcaga cggcgctcac ggtgatgccg cagcggccgt tcgggccgtc 3421 cgtcgtcagg atgttgacgg ccgccgggag gtgcgccatc gcctcccgga aatcggcctg 3481 gctgggggtc acggcgatgc cgctcctctc gtgtcgtccg gccatcagcg catgttcagg 3541 ccgccgttgg cgtcccagca cgctccggtg accgtgtccg cgtggtccgc ggcgagcagc 3601 acggccatgt ccgcgatgaa ctcgggccgt cccaggcggc gcacggggat ggactcctcg 3661 atccgggcga gctgttccgg ggccaccagc tcgcggacga cgggcagatc ctgcactccg 3721 ggggcgatcg cgttgaccgt caccccctgc gggccgagtt cgcgggcgaa gaccttggtc 3781 agggtggcca ccccgccctt ggccgccgcg tagtggccgc cggtggccga gccgccgttc 3841 tgaccggcga gggaggcgat gttgacgatg cggccgtagc cgcgcccggc gaagtaggcg 3901 ccgaagacct ggcagccgaa gaacgtgccg tcgaggttgg acgacacgac cgagccgaag 3961 ctgtcggggg tgatctccat caggggctcg accttcgagt acccggcgtt gttgaccagg 4021 acgtggacgg cgccccagcg tgcgacgagc tggtcgcgga cgcgtacgaa ggcgtccttg 4081 tcgcgcacgt ccaggccgag gccgatggcg ttccgcccgt ccggggcgag atccgccgcg 4141 gccgcgacgg cggccgcctc gtccaggtcg gtcagggcga cgcggtagcc cgcgccgtag 4201 agcctgcccg cgatgcacgc gcccagcccg cgggccgcgc ccgtgacgag cgcgacccgg 4261 tcgggggtcg tggtggtcat cgggcggcct ccggctccgg caggggacgg ccgatgcgcg 4321 cctcgatctg catatagcgc cacagcccgt gctcgccgac ctggacggtg cggaagaggt 4381 tgcaggcggc ggcgaccgtc ggctggtcga ccacatcggc gaggaggtac gaggtccagg 4441 gccacgaacc ggacgggccg accatgtgct gatcgtcgtc catggtgccc aggacggtca 4501 ccccgggcag ctcgcgcagt tgcgtgagca tggtcatgaa gccgtcccag accgccttgc 4561 cctggccggt gggcaggtcg aagaagttct ggttgacacc gatacagaag agcacgcgca 4621 ggggcgctgg ggtggcatcc gtcatgatga agttccttgc ctgcgaggtg agttggggtc 4681 ggggtgttct acaggaagcc ggggaagggc tgaacgccca tgagcacggc accggcgccg 4741 tcgtacatgc cctcctggag gaaggcgtgc tgcgggacca cggaggcgtc gcgcagatag 4801 cgctgcatgg ggctgtcgtc ggcgatggcg gcaatgccgc cgagctggta cgcggcccgg 4861 acgacctcga aggaggtctt cgcgagatgg gcggcggcca gccgcagcag accggtctgc 4921 cggtcgggtc gcgtggcccg cccgccacca ccgtctccca ggtctcctcg gtggcctcgt 4981 agaagaaggc gcgagcggac cggagttggg cttcggcctg gccgacggcg atgcggtagg 5041 tggcgcggtc ggcgggccgg ggcgcgccgg tgtagcccgc gcggcccccg gcggcgatgg 5101 cctggtcgag cgcggcgcgg gcgacgccga ggccgacgac ggccagcacc tgggcggcgt 5161 acgggacggt cgggtagcgg tacagcggct cgtccacggt gggctcgccg ccgcggacga 5221 acgtccactc ctcggggacg acggcgccgt ccaccaccag gtcgtggctg ccggtgccgc 5281 gcatgccgac cacgttccag ttgtcggcga tccgtacctg cccgggccgc agcaccgcgg 5341 tcaggggccg gccggtggcg tcctcaccgg ccttgatgcc cacgccgagg acgtccgcgc 5401 ccgtgcagcc gctggcgaac ctccaccggc cgcggacccg gtagccgccc tcgacgcgct 5461 cggcgggctg caccgggaac agcccgcccg cgaacaccac atcgggcccg tcggcgtaca 5521 gctcggcctg ggtctccagg ggcagcgcgg ccaggtagac gagggacgaa ccgaaactgg 5581 cgacccatcc ggcggagccg tcgacggccg atatccgctc gatgagtgcc aggaatcgtg 5641 cgggcggcag ggggtcgccg ccgaagcgct tcggggtgct cgcccggtag aggcccgcgc 5701 gcttgaacac ctcgatcaca tcccggggga tgtgccgctt ctcctcgaat tccggctgcc 5761 gttcggccac cacggtcagc acgtcgtcga tcggatccgg cgaccgggtg atgggagttg 5821 cttgggtcat gggagatgct cctcgcgttg cccggcggtt ccctcccccg cctgacgacg 5881 acgctacgcc cgccaacggg ccgtcggcca ttggggattc ggcggcgttg ggtaggggaa 5941 ttcccctaca cgcccgctgg cagcgtgaac cggaagaccg cgccgtgcgg ctggttcggg 6001 gtggcgtcga tccggccgcc gtggcgggtg atgatgcggt ggctcagcgc cagaccgatg 6061 ccgctgccgt tctccttgga cgtgaagaca ccgtcgaaga tgcggtcgcc gggcggcagc 6121 ccgttccccc agtcggtgac ggtcagctcg gcgtccccgt ccgccatcag gcgcgtggcg 6181 atgcgcaccc tgcgctcggc gagcggacaa cgcgccatct cgtcgacggc gttgaaggcg 6241 aggttcatga cgacctgccc gatcaggacg ttctcgcagc gcaccggcag cggctcggcg 6301 gtgaggtcga gcgcgacggc caccgagtgt tcctgggccc gcagctcgat gaagtacgcg 6361 cagtcgcgca cgatggcgcc caggtcggtg agccgctcgg acggctccag gcggcccacg 6421 tagctccgca ggctgcccag gatccggcgg gcccgctcga tctgccgggc ggcgttgtcc 6481 agcccgaagg ccacggaggt gtcgtcggtg gcgaggcggc cgcgcgctcc ctcgacgaag 6541 ttgtaggcgg ccgcgagcgg ctggctcacc tcgtgggcga tcgccatcgc catgtcgccc 6601 atggcgttgt accgggccag gtggtcgagg tgctgggttt cgcggcggtg ttcctcctcc 6661 gcgcggaccc ggtcggtgat gtcgtagaac aggagcatcc ggccgcgcag atcgctctcg 6721 atctcgatgt gctggcaggt cgacgcgtac cagcggggtc cgtcgccggg cgccgcgaac 6781 cggtagcgcc cctcaccggc ggtgggtacc ggcccgtcgt ggcagtagtc ggcgaagtcc 6841 gcgccgcgga ggccgtcgcc gagcagccgg acggccgact cgctcgcgaa gacgacccgg 6901 tccccgtcgt cgaggacgac gatgccctcg gcgaggctgc ccaggaaggt gcgcagcctg 6961 ctctcggtgc gacacagatc gcggcgtacc gccttctcct cggcgatgtc gcggaactgg 7021 accatcaccg ccgtccgccc cggcaggtcg acgcggatcg cgatcgcctc ggtgagggtc 7081 tcctcgccgg tcttggaccg gtagcaccac tcggtggcgc tgaccccgtc ctcgacggcg 7141 cgcccgagcc agcggtggcc gagttcgcgg ctgtactggc gggcgttctt gctcatgtcc 7201 ggcgccttga gcggcttcag ctcgtccacg gaccagccga gcaggtcgca ggccgcccgg 7261 ttcgcccaga ggatctcgta ggtgcgggcg tcgtgcagca gcacgcagta cttcagggac 7321 tgcatcagca cccggaagtc ggccggttcg acggggctgc tcatggggtg cctctcaccg 7381 gtcggcggcg ggccgcagcc ccagccggag cacatcgcgg acgagggtgg ccatgctctg 7441 cgcaccggtc ttctcccgga tccgggcgcg gtgcacgtcg atggtcttgg cgctgatgcc 7501 gagccgcgcc gcgatctgct tgttcgccat gccgtcgacg gccagcccga gcacttcccg 7561 ttcgcgggag gtcaggctgt ccagcttcgc gcgcagttcg cactcgaccg cggcgcgctc 7621 gaaccgctcc cgcgcggtgc gcagcgcggc ctgcacgacg tcgagcatgt gctgcgggtc 7681 gtacggcttc tccaggaagt ccacggcgcc gttctgcatg gcgcgcaccg acatccggat 7741 gtcgccgtgc gcggagacga acaccacggg cagcggcgcg cccgtctcgt tcagcagctg 7801 ctggacgtcg aagccgctga gttcgggcat gcggacgtcc aggatcagac aggcgggccg 7861 ggcgcggtcg taggaccgca gaaaggcccg ggcgtcccgg aagcgctccg agcggatgcc 7921 gaccgactcc aggagccagg cgagcgaatc gctcagctcc tcgtcgtcgt cgaggatgta 7981 cacgagggtg tccgtggtgg cgtccccact catcgcccgg ccccgatgcg catcgtgctc 8041 cctcccggcg gttgctgtcg caaggagcgt aaaccgtgcc gtgaacgtgc aggtcaggcc 8101 gccggttccg gggcttcccc ggggtcaggc ggtcaccttg gcgaggaacg cggcgacgtt 8161 ggccgtggtc cgctcgatct tctcctccag ggtgagcgac tcgtggagcc gtgcgcccgc 8221 gcccgcgtcc ttcttgccgc gtacgtacag cgagcaggcg aggtcgctgc atatgtaggt 8281 gccgacggag ttgccctgct gcctggcctt ccccgccttc ggcgcgacca tcagggagac 8341 gccgtcggcg ggggaggtca gacagagcga gcacatgccg cgctgcgtct gccaggaggc 8401 gggggtgggg cagcgcaggg cgagggcccg cgggcggtcg tcgagcaggg tgacgaggta 8461 agcgcggtcg taggcctggg gatcccgcca gccgaggtag tccaggtcgt cccagggctt 8521 ggcggccaga tcgcgcggta cggacaggcg cttcgcctcg cccttggtgc agttgacgaa 8581 ggcggaacgg atctcttgct cggtcagcgg cttcatgacc gggaggctaa gttgcctaaa 8641 ggtcttaggc aaacgaataa tgggctctgt cgacggaggg gcagggcatg gcatacgcag 8701 ggctgaccgc ggaacggctg acccgggccg gggcggaact ggccgacgag gtcggcttcg 8761 accaggtgac cgtgtcggag ctggccaggc ggttcgacgt caaggtcgcg agcctctact 8821 cgcacctgaa gaactcccgc gacctcaaga ccaggatcgc cctgctcgcc ctggaggaac 8881 tcgccgaccg ggccgccgag gccctggccg ggcgggccgg gaaggacgcc ctgaccgcct 8941 tcggcaacgt ctaccgcgac tacgcccgcg agcaccccgg ccgctacgcc gcggcccagt 9001 tcagactgga cccggaggcg gcggccgcca gcgccggtgg caggcactcg cagatgacgc 9061 gggcgatcct gcgcggctac gacctcaccg agccggacca gacgcacgcg gtgcggctgc 9121 tcggcagcgt cttccacggc ttcgtcagcc tggagctggc gggcgggttc agtcacagcg 9181 cccccgattc ggcggaatcc tggtcccgga ccctggacgc gctggacgcc ctgctgcgca 9241 actggcccac gccctgacgc gcacgcccct gacatcggac gccgcacgcg cgcgcatagc 9301 ccattcgccc tcttacggcc gttcccgctc cgtgacggtc cccgctccga tgacctgcgt 9361 aaatgatcaa gcggagcggt gaccctgacc tcgcgaggtg acgcttcgtg ttgcggcggt 9421 ggcggactgt cggttgtctc aagagcggaa cacctatagg tgccgcgtga tcacgacggc 9481 cactgctccg ttggaggatc ttcatgcgtt acgtacccgc cggtgcaggc atcggcctgg 9541 ttctctgtgc cctcgcgctc cagggcccgg ccgccgccgc cgatgactcg gagctccgca 9601 tcagcccgaa gaagagcgcc ccgggctcca cggtcaccgt cagtacgacc gcctgcggct 9661 cggacgtgac ctacggcaag ggcaccgcgg gcggagacga gttccacctg ctcgacgacg 9721 gccacaaggg cacgctcacc ggcaccttcc ggattccgaa gggagccgac tccggcagcc 9781 acgaggtcat cgtgaagtgc ccgccgagca tcaagatcac ggacacggtc aaggtcaagc 9841 gcagccaccc cagtggcggg gtcgacgccg gtttcggacc tgccgcggtc ggcgacaaca 9901 agccgaccct cctcggcgcc accgtcctgg ccgtcaccgc cggaggtgtg ctggtgatgc 9961 gccgccaccg gagcgtccgg cgctagccac ctcgaccggg gtggcgtggg acgcggaggt 10021 ggccgtcgtc ggcgcgggtg cggccggtct gacgctggcc caccggctcg ccgccctgcc 10081 ctccccgccc cgcgtcctgc tggtcggggc gccggacggg ccgctgcggg cgccggagcg 10141 gacctggtgc tggtgggagg agcctggcgg tgagttcgac ggggcactcg ccgcccgctg 10201 gagccgggtc agggtgcacg gagccgacgg ccgcccgctg gaccgggagc tggcgccctt 10261 cgtctacaag atgctgcggt cgcgcgactt cgagcactgg atggccgccc ggctcgacgc 10321 ggcgccctcg gtgcggcggg tcgaggcggt ggtggacgag gtacgcgacg acgcgggcgg 10381 cgccctggtg cggggcgcct gcgccggggg ccgcccggtg atctggcgcg cccggtgggc 10441 gttcgactcc cgcccggcgg ccgccctgcc accggcccgt acgacgctgc tccagcactt 10501 ccggggctgg ttcgtccgct gcgacgcccc ggccctggac cccgcggtgg ccgagctgat 10561 ggacttccgc accccgcaac cgcgccgggg cctgtcgttc ggctatgtgc tgccgctgag 10621 cgaccgtgag gcgctcgtgg agtacaccga gttctcgccc gccgtgctgg aggacgccgc 10681 gtacgacgcg gccctgcgcc actacaccgg ggccgtgctg cggctgccgc ccttccgggt 10741 gctctccacc gagcagggcg tcatccccat gaccgacggc cgcttccccc gccgcgcggg 10801 cgccgccgtg ttccggatcg gcaccgcggg cggcgccacc cgcccggcca ccggctacac 10861 cttcgccgcg gtgcgacggc agtcccacgc ggtggcggcg gccttcgccg cgggccgccg 10921 cccggtgccg cccgccccgt atccggcccg cgcgctcgcc atggacgcgg cgatgctgcg 10981 cgccctggac accggccgag tggccggggc ctatgtgttc accggtctct tccnnnnnnn 11041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnna 11281 tcgcggggct cgcggcggcc accgcgctgg ccgagcgcgg ggccgcggtg gtgctgtacg 11341 agcgccgcgc gatgctcggc gggcggctgg ccggatggcc gacgatgctc gcggacgggt 11401 cggcggcgac gatgtgccgc ggtttccacg ccttcttccg gcagtactac aacctgcgcg 11461 ggctgctgcg gcggatcgac ccggccttac gcatgctcac cgggctgccg gactatccgc 11521 tgtggcacgg ctcgggcctg cgcgacggtt tcgcgggcgt gccgcgcacc ccgccatggt 11581 ccgcgctggg cttcgtggcg cgcagcccgt cgttcggctg gcgggatctg gcgggcctgg 11641 acccggtggc cgcgctgccg ctgttcgacg tccggctgcc gtggatccac gaacggctgg 11701 acgcgctgag cgcggcggag ttcctggacg cggtccgctt cccggcggcg gcccggcacc 11761 tggcgttcga ggtgttctcc cgcagcttct tcacggatcc gggcgagctg tccgccgccg 11821 agctggcggt gatgttccac atctacttcc tcggctccag cgagggcctg ctgttcgacg 11881 tggtgcgcga gccgttcccg tacgcgctgt gggatccgct gcggcgctac ctggagggcc 11941 acggcgcaca ggtgcggccg ggcgccgccg tggagtcggt acggccgctg gacggcgggc 12001 gggtggcggt ggacggcgag gcgtacgacg gggtggtgct cgccctggac acggcggggc 12061 tgcgcacgct ggtggcgaac tcccccggcc tgggcgaccc ggggtggcgg gagcggatcg 12121 cggccctgcg gaccgcaccg ccgttcctgg tctcccgcct gtggctcggc gcgcccgtgg 12181 acccgggccg ccccggtttc ctcggtacga gcggttacgg cccgctcgac aacgtcagcn 12241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 12301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 12361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 12421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 12481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 12541 nnnnnnnnnn nnnnnnnnnn nnnnctggtc cgtaccgatc tgccggtcgc cctgatggaa 12601 cgggctgcca ccagcgggtt cctggccgcc aacgcgctgc tcgcccgctg gggcgtgagc 12661 ggccagcggc tgtggacggt gccccgccat ggccgtacgg ccgtgctgcg cggtgtgcac 12721 cggctggccg ggaagcgcca ccggccgtga ccactgcggc ccgccggtca gcccgggaag 12781 cggcccgcct cgcgcagggc ccagcggcgt tcggcgtagg cgaggtcgtc gcgccacagg 12841 cggcccgcgg cggcgcgcat caggggccgc agcaggggtg cggccgcgcg ggcgacggcg 12901 aagccgggtc ggtcggacgt ggcgaggacc gcctcgatga cggcggtgcg cggacggccg 12961 tggttctcgg gggtcagcgg ggtggcgtgg gtttcgacca cggagccacg gccctcgcca 13021 tcggtgatgc gcatgacgac ggtgcggggc ccgggtgcgg agaacacggc gcggacgggg 13081 acgaccacac gaccggccac cttgaaggac acccggacgg cgaggccgtc gtcgccgtcc 13141 ggctcctcga cggtgagatc gacgaaggag tacgggtgga gccacccgcc gtgccacggg 13201 tcgaggcggt tggcgacgac atcggccggc tcgcacgtac ccgtgacgtc gtggacggcg 13261 gcgagcgtgg caccggccac cgggcggggc ggcagcaccg ggcgttccag cggctcctcg 13321 ccgccggccg cgtcgagccg tacccaggcg aggacaccgt cgtcgtgggc gggcagcgga 13381 caccagcccg tggcggcgtc cccgggcagg gcgaggccgt gccagtggca gaggagcgtg 13441 ccgcggctga ccaccgcgtc cttcagcggc gccccgaggt gcgggcaggc gccgggtccg 13501 gcgacgagac gtccgccggg gccgcgccag gccaccacct cggtaccggc gacggtccgg 13561 ccgaaggggc ggcccggggc gacggcggcg gacgcgccga gcacgtacca gttgccggac 13621 ggtcggtcct gcgcccgctt cagggccgcg gcgatcaggg cgggcctggc ctcccgccag 13681 gtggaccgct gccggtccca ggggacaccg cggcggcgca gggacagcgg gaggcggcgg 13741 gtggcggagg gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 13801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 13861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 13921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 13981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 14941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 15841 nnnnnnnnnn ncgcttcgcg cggcccggcg aaggcccgta cccctctcct ccatggcgtc 15901 cgcgccggtg tggacgtcga ggctgctgcc gtcggcgaac gcggcccggt aggcggggtg 15961 cagcgccacc aggtcgagcc ggtcggacag ctcctccccc acggccgcca gcggctcggc 16021 cagcaggtcc ggcatggtga gcacggtggg tccggtgtcg aagcggtagc caccgcggtc 16081 caggcgtccg gcccggccgc cgggccgggt ggcgcgttcc acgacggtca cccggcgccc 16141 ggcgccgagc aggtgcaagg tggcggcgag cccggacagg cccgctccga cgaccacgac 16201 atggtccgtg ggcccggcga cggtcctcat ggttccagtc ttctgacgtc cgggccgccc 16261 acccgtgctc ggggccgtac ggccgaagga attcgaccgt gcgtggcccg ctacttccgc 16321 ggacccggca ccggcagccc cgggccggtg cagtgcacat cgcccgccgg gaggcgaccg 16381 tcgaccagat acgcggcggc cgtccggtcg acgcaggcgt tgccgcggct ggcgaacacc 16441 ccgtgggagt agtcctggtg gagtgtcacc agccgcgagc ccggcagccg gtggcggagc 16501 cggtgcgccc cctcgatcgg cgtgacgggg tcgtgtgcgg aggcgatgag caggccgggc 16561 ggggcgtcgg ggccgccgag cggggtgcgg cgggccggcc ggtggtgcca gtaggcgcag 16621 gtggacgcct cgatcccggt gaggaccggg tgcgggtcga ggtgccgcat gcgccgcacg 16681 tcggccacca cccggcgggg tgcgggggcg tggccgtccg cgcacttcac gatgcggttg 16741 gcggcttcgt aattgcgtga ctccgggccg tcgaaggnnn nnnnnnnnnn nnnnnnnnnn 16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 17761 nnnnngtcgg tggcggcgtg ggcgggtgcg cccgggagga gggcggcggc gcttgccccg 17821 agcgcgcacc acagggcggt gcgtcgtgca gccggagtca tgtgtctcgc aatcagctca 17881 ggcagatctg gtcggatcat cagatgacaa tgaaaacgat tatcgatatc gtctaggcgg 17941 tcaagacggg tgcccctgcc gccaaggccg ctgcccggcc tgcccggaac ctcaaccgca 18001 cggcgacgaa ggagagttgt ggctcatctg ctgatggtgg agagctgggt cggatcgatg 18061 agcaggctgc tgccacgggc gatccgcgag aacgggcacg agttcacctt cctcacccgt 18121 gacctgcacc actacctgcg ctccgcgccc gagggcaccg cccacccgct gctcgccgcg 18181 cgccacgtgc tgaccgccga caccaacgac accgccaccc tgctgccggc ggtcgagcgg 18241 ctgcacacgg ctctcggttt cgacggggtc atcacctcct gcgactacta cctgccggtg 18301 gcggcgcgcc tcgcggaccg gctggggctt cccggcccgt cggccgaagc ggtggggaac 18361 gcctgccgca aggacgcgac ccggcgcgtc ctcgacgccg ccggagtgcc cggaccgcgg 18421 ttcgcggtgc actccacgtg ggccgaggtg gcggaagggg cccgggagat cggctatccg 18481 ctggtcgtga agcccgtgga cctgtgcgcc gggatgtacg tacggcgcgt cgacgacgag 18541 gccgcgctgc gggacgcgtg gcgtgcgctc gacggcttcc cggtcaacgc ccggggccag 18601 cgccgctccc ccgccgtgct gctggaggag ctgctcgacg gcccggaggt cagcgtcgag 18661 accgtgtcgt acggcggcac caccgaggtg atcggggtga ccgacaagag cgtcggcggg 18721 gcgcccgcgt tcatcgagac cgggcacatg ttccccgccg ccctcgcatc cgccgacgcc 18781 gcggccgcgc gcgagaccgc ggtgctcgcc ctgaaggcgc tcggcctgga cgacgtcgtc 18841 gcgcacaccg agatcaagct gaccgccgcc gggccgcgcg tggtggaggt caatccgcgc 18901 cccgcgggca accgcatcac cgaactgatc cgccatgtca cgggggtcga cctggccacc 18961 gcctgtgtgg acgtcgccct cggccaccgg cccgatctgc ggggctggga cacggggatg 19021 cgcagcgccg ccatcggatt cctggtgccg gccaccgcgg gcaccctggc ctcggtcgac 19081 ggcggtgacg cggcgcggga ggcgccggac gtgctggagg tccagctcgc cgagcccggc 19141 aggagcgtcg aggcggccgg gagcaacaac gcatacctcg gccatgtcat ggcgggcgat 19201 cccgaagggc ccggggcccg cgcccgggtc gaagcgctgc tgtccggact gcgcccgcgg 19261 gtggtggccc catgaccgcg cgcccgctca ccgccgcgcc gccgtgtttc tcgtacgagg 19321 agctggccga ccgggtgctg gacggcgcct tcgggcccga tccgcgcacc cagcggatcg 19381 ccgtggcctt caccacgcgc caggccgtac gccacgacgg ccgcagcggc ggctatcgca 19441 acgaggtgct cagcctgcgg ctgggcgagg ccgtcggctc gtgcgcggtc gagccgggcg 19501 cactgcccta cgaggcgatc gacacctgcg tcggcgtgga cgtggcccgg ctgctgcgcc 19561 acgagctggc cccggtccgc gtcgccgccc tcgacgcgta tctcctgcgg atgctgccgc 19621 acacctccgc gtccggtgcg cgcccccagc cgctggccgc cgggacatcg ctggagaagt 19681 cccgcgcccg cgccgaggcc gtcaccgggc tgctcgggcc ggggccgggc cggaccgttc 19741 tggtcgtcgg tgtcgtcaac tcccttctgg agagcctgcg ttcacgtggc ctgggctatg 19801 tggcctgcga tctcaagggc ggtacgacgg aatggggcga gccggtcgcc accgacgcgc 19861 tcgcccagct ggaccgctgt gacgccgtgc tcgcctccgg catgacgctc ggcaacggca 19921 ccttcgaacc gctgcgggaa cacgcgctgc gccacgggaa gccactggtg atgttcgcgc 19981 agaccggcag cgcgatcctg ccgcgcttcg tgggcgccgg ggtcacggcg gtgtgcgccg 20041 agccctaccc gttcttctgg ctggacggcg gccccgggct gatccactgc tacggagggc 20101 actacggggg tcccgcatga ccacggccgt ccatcacccc accgccaacg gcgacctcct 20161 cgcgctgctc ggccgcaccc cgctcgcccg gatcaccacc gatctgccct gcccccatcc 20221 cggtttctgg gccaagctcg aagggctcgg cgccggtggt atgaaggccc gcgccgcggt 20281 gtccatgctg ctcggcgccc gggagcgcgg tgaactgcgg cccggtgcgc cggtggtgga 20341 gtccacctcc ggcaccctgg gggtcggcct ggccttcgcg ggccaggcgc tcggccatcc 20401 catcgtgctg gtctgcgaca ccgagctgga accgtcgatg cggcggttgc tgcgcaccta 20461 cggcgcccag ctggaactgg tcgaccgccc ggcggccgag ggcggctggc aggccgcccg 20521 tctcgcccgg ctgcgcgcgc tgctggccct gctgccggac gcctactggc ccgaccagta 20581 caacaacccc gacaacacgg ccggttacgc ctcgctcgcc cacgaactga ccgcccagct 20641 cgaccacctc gacatcctgg tgtgcagcgt cggcaccggc ggccacagcg cgggcatcgt 20701 ccgcccgctg cgcgggcgct ggcccgggct gcggctcatc ggcgtcgacg ccaccggctc 20761 gaccatcttc ggccagcccg cccggccccg gctcatgcgc ggcctgggca gcagcatcca 20821 tccgcgcaac gtggcctacg gcgccttcga cgaggtccac tgggtcggcc cggccgaagc 20881 ggcggactcc tgccgacggc tggcccgggg cagcttcgtc agcggcggct ggagcaccgg 20941 cgctgtcgga ctcgtcgccg cctgggccgc ccgcgtccac cccggcgccg tggtcgccac 21001 cgtcttcccc gacgggccgc accgctacct cgg //