LOCUS       NZ_EQ973330            22601 bp    DNA     linear   CON 09-FEB-2024
DEFINITION  Corynebacterium matruchotii ATCC 33806 Scfld2, whole genome shotgun
            sequence.
ACCESSION   NZ_EQ973330
VERSION     NZ_EQ973330.1
KEYWORDS    WGS; RefSeq.
SOURCE      Corynebacterium matruchotii ATCC 33806
  ORGANISM  Corynebacterium matruchotii ATCC 33806
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Corynebacteriaceae; Corynebacterium.
REFERENCE   1  (bases 1 to 528914)
  AUTHORS   Fulton,L., Clifton,S., Chinwalla,A.T., Mitreva,M., Sodergren,E.,
            Weinstock,G., Clifton,S., Dooling,D.J., Fulton,B., Minx,P.,
            Pepin,K.H., Johnson,M., Bhonagiri,V., Nash,W.E., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2009) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   2  (bases 1 to 528914)
  AUTHORS   Fulton,L., Clifton,S., Chinwalla,A.T., Mitreva,M., Sodergren,E.,
            Weinstock,G., Clifton,S., Dooling,D.J., Fulton,B., Minx,P.,
            Pepin,K.H., Johnson,M., Bhonagiri,V., Nash,W.E., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2009) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/09/2024 04:16:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,707
            CDSs (total)                      :: 2,652
            Genes (coding)                    :: 2,612
            CDSs (with protein)               :: 2,612
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 40
            CDSs (without protein)            :: 40
            Pseudo Genes (ambiguous residues) :: 0 of 40
            Pseudo Genes (frameshifted)       :: 8 of 40
            Pseudo Genes (incomplete)         :: 32 of 40
            Pseudo Genes (internal stop)      :: 3 of 40
            Pseudo Genes (multiple problems)  :: 2 of 40
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:24:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 432413
            Orig. end                         :: 455014
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            EQ973330.1.
            Corynebacterium matruchotii (no 16S rRNA gene sequence available)
            is a member of the Actnobacteria division of the domain bacteria
            and has been isolated from the oral cavity.  The sequenced strain
            has been obtained from Sue Haake (ATCC 33806-
            [http://www.atcc.org/ATCCAdvancedCatalogSearch/ProductDetails/tabid
            /452/Default.aspx?ATCCNum=33806&Template=bacteria#10213]).
            This is a Newbler assembly
            (http://www.454.com/enabling-technology/the-software.asp) comprised
            of 1/2 plate FLX PE 454 DATA with a Q20 coverage of 24.6X.
            This strain was sequenced as part of the NIH Human Microbiome
            Project. One aim of the HMP is to build a catalog of reference
            genome sequences of organisms comprising the human microbiota, and
            this sequence is contributed as part of that effort. This work was
            supported by the National Human Genome Research Institute and the
            NIH Roadmap Human Microbiome Project
            [http://nihroadmap.nih.gov/hmp/].
            Corynebacterium matruchotii (no 16S rRNA gene sequence available)
            is a member of the Actnobacteria division of the domain bacteria
            and has been isolated from the oral cavity.  The sequenced strain
            has been obtained from Sue Haake (ATCC 33806).
            This is a Newbler assembly
            (http://www.454.com/enabling-technology/the-software.asp) comprised
            of 1/2 plate FLX PE 454 DATA with a Q20 coverage of 24.6X.
            This strain was sequenced as part of the NIH Human Microbiome
            Project. One aim of the HMP is to build a catalog of reference
            genome sequences of organisms comprising the human microbiota, and
            this sequence is contributed as part of that effort. This work was
            supported by the National Human Genome Research Institute and the
            NIH Roadmap Human Microbiome Project
            [http://nihroadmap.nih.gov/hmp/].
            Product names were updated in June 2013.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22601
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22601
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22601
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12601](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12601
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            26..1177
                     /locus_tag="CORMATOL_RS13430"
                     /old_locus_tag="CORMATOL_02540"
     CDS             26..1177
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /locus_tag="CORMATOL_RS13430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02540"
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_005522751.1"
                     /transl_table=11
                     /translation="MSEWPTVKLGEVAEQTNHRVGELDVPIYSVTKYDGFVPSSEYFKK
                     RVFSMDIRKYKLCTAGDFAYATIHLDEGSIGISPVKCGISPMYTTFRLNSLNISPDYLL
                     RYLKSSRALTQYLTLGSGSAERRKSIKFTDLRKMEIPFPPLGEQNRIVGILGKTTGAIS
                     SVQKQIEQAKKLRSSIVGMASKMAVELRAISEYFDINPRQPRNIPDNAPTSFVPMANLD
                     ETFGISPITSRFSEHKKGYTYFENGDILLAKITPCFENGKSAIAKLSTQIGHGSTEFHV
                     LRHKNHMHQDVCLSPLLVAAILKQPSFLKPAENFMRGSAGQKRIPVSYIASLKVPVLKS
                     VDLEKIDQSLEIVEALLNLYHRKLSLLQELQKSLATRAFAGLL"
     gene            1219..4695
                     /locus_tag="CORMATOL_RS10530"
                     /old_locus_tag="CORMATOL_02541"
     CDS             1219..4695
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006061454.1"
                     /locus_tag="CORMATOL_RS10530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02541"
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="WP_005522752.1"
                     /transl_table=11
                     /translation="MITPQPSNFAFIGRVWPELLIHCRNAEQSAVSNPRVAGIEARFTL
                     ERLVDHIVEAYGLRSVSDWNLNDKLNHRSFKDRVNQRIHDKMNVLRRFGNDAAHNPDHI
                     DPERAVRAIGQLFDILVWAAVNVARPPLERTKLPTFDRSIVYNAPKQRQRSQQEIAKLN
                     QQLQKAVDEIETTKLLLTEREETWRQERKAHLDQIAAFKGQTEELARARDQLEAELAQL
                     RADIAANTRSIDTSNNFAISEAETRRDLIDPALAEAGFNVARGNLKTEFCLADGKGVVD
                     YVLFGDDGRPYAIVEAKRAGKAIDAGRQQAEYYADELEKQFGLRPIIYYTNGHEIRLLD
                     DAANLPGIGAGAGYPSRAVEGYATKDELYAMIRRRTQRQDLNTVSVDTQIAGRPYQITM
                     LQAVAERFGAGHRRALLVMATGTGKTRTAIALVKQLAQAGWVKNVLFLADRKSLVKQAA
                     EAFSEHLRDMPVVDLLRNQHGTGQVYCSTYQTMMKLLGSRFGTYQFDLIIVDEAHRSIY
                     RRYSRIFDYFDSLLLGLTATPRCDVDHNTYALFQLNDGQPTANYSLDEAVDEGYLVPFK
                     AFQCSSVILRDGVAYKDLSPEEQQQWENQDWGIDDDGLPLDIPLEVESEEINLKLYNKD
                     TIRKVVGQVLCHGIKVAGADRIGKTIFFTRSKKHAQLVCDIIHETNPQVRAAVITHEVY
                     DSLDLIDRFKASGKGSLDVAISVDMLDTGVDVPAVVNLVFFKPVYSNTKFWQMIGRGTR
                     LAPNLFGKGLDKREFYVFDYCDNLRRFEDAEHIVSTTGSQQRPLSERTFLKRIELASLL
                     PADDPTRADLVSGLRNQLQTVPISSVLVRPEDRAELEHYLCADAWGSGTDIESAGKLAY
                     LPFADDPEDEEQAKRFDYLMLTLQLALARGEALPTRHRDRVTNIARHLLSKTNVPRVAD
                     AASTLEHYSEDLWWEGITIADLELARRTLRTLVQFIDPGYRSEVVLDIEDELAEPAEFN
                     LPTETANLSYSSVEDQLREVLEKHLDDLPIQRLRKMKPLTAMDLAALEEIIAGVEGVDE
                     FRARIGDQSIVGFVRSLIGLDQEAVQEQFADFLSRSNLNAKQQEFLRRIIRVLAKTGSL
                     TIGQLFEEPFKDLGNVFDVFPGDDTIVYDLKDRLDRIGKMDVAGGGVGEAG"
     CDS             4829..5029
                     /gene="allorf_437242_437442"
                     /locus_tag="allorf_437242_437442"
                     /protein_id="allorf_437242_437442"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGVSGSWLYGAAFLKLQLSTCEAWLWRGVGWPCAGAASLVGWGLL
                     VQLCRGACFSISPSPPNLKPR"
     CDS_motif       4829..4861
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGVSGSWLYGA"
                     /locus_tag="allorf_437242_437442_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4862..5029
                     /prepeptide="core"
                     /locus_tag="allorf_437242_437442_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.10"
                     /molecular_weight="5805.8"
                     /monoisotopic_mass="5802.1"
                     /core_sequence="AFLKLQLSTCEAWLWRGVGWPCAGAASLVGWGLLVQLCRGACF
                     SISPSPPNLKPR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGVSGSWLYGA"
                     /leader_location="[4828:4861](+)"
                     /alternative_weights="5823.9"
                     /alternative_weights="5841.9"
     gene            5334..6527
                     /locus_tag="CORMATOL_RS10540"
                     /old_locus_tag="CORMATOL_02544"
     CDS             5334..6527
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005524957.1"
                     /locus_tag="CORMATOL_RS10540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02544"
                     /product="S41 family peptidase"
                     /protein_id="WP_231289037.1"
                     /sec_met_domain="Peptidase_S41 (E-value: 4.5e-20, bitscore:
                     66.7, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIMNDTGKGATALRASLGFPLYVKPRSLRGPSQSLVRNSRGNSK
                     NNCAKPGGLGRPNRPSSGTATRRGRATAMKVVKTLTIIIAVIAVLVGAITWFFGPSLGV
                     ALLGRPILMVSTPHRYGQAAIDIGRSFAIYADTPQATAAYEEAKAEIANVHSVEETYPI
                     IKKYLKVAGGKHSNFLSPEDNATSDDLGNDSPTVTKNDNIVTAMLPSLNLGPVGQKYAD
                     ILANGLAENVPNSCGVILDLRKNDGGDMGPMLAGVSGLLPDGTLLSFKSKNSTSPVTLN
                     NGSISGGGTPTTVGPKDKFRVPVAILTSNVTASSGEATLLSFRGLENTRTFGQPSAGYA
                     SGNLIIDMPDGAGLMVTTANDMARTGEEFSEDPIAPDVSTDRPEQAATEWLHSQCGQ"
     gene            6738..6980
                     /locus_tag="CORMATOL_RS10545"
                     /old_locus_tag="CORMATOL_02545"
     CDS             6738..6980
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005525105.1"
                     /locus_tag="CORMATOL_RS10545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02545"
                     /product="hypothetical protein"
                     /protein_id="WP_005522756.1"
                     /transl_table=11
                     /translation="MKLGNIFRGPKWPRAAAEFIATHFADKSVTEFFDEPRFERFLYLA
                     KTETWVEAAREYRDVTGEDIQSSIIAAEVARRTFR"
     gene            7667..8215
                     /locus_tag="CORMATOL_RS10550"
                     /old_locus_tag="CORMATOL_02546"
     CDS             7667..8215
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CORMATOL_RS10550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CORMATOL_02546"
                     /product="hypothetical protein"
                     /protein_id="WP_005525497.1"
                     /transl_table=11
                     /translation="MDVDKKDRNEILVAMIIYTLMLVLLGRRLLDLVIWHRIPHSFGVL
                     LAERADEGMIPLSLADSVAKSLLISGFLLSLLGIVVVATTLILLARQLLKGQFFTAYNV
                     KCFTIGSLSLGVYFLGVFVQNMGANEMAAKLNLRSWFDYSEAQSLDYIAMFLFVETLVL
                     LAVVIRRGISMQEDQEGLI"
     gene            8234..8428
                     /locus_tag="CORMATOL_RS10555"
                     /old_locus_tag="CORMATOL_02547"
     CDS             8234..8428
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005288987.1"
                     /locus_tag="CORMATOL_RS10555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02547"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_005525452.1"
                     /transl_table=11
                     /translation="MVCHLDQLLAEREMTLAALADQVGVTVANLSVLKNNRAKAVRFTT
                     LVALCDALDCQPGDLFTAE"
     CDS_motif       8234..8287
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVCHLDQLLAEREMTLAA"
                     /locus_tag="CORMATOL_RS10555_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8288..8428
                     /prepeptide="core"
                     /locus_tag="CORMATOL_RS10555_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="4772.4"
                     /monoisotopic_mass="4769.5"
                     /core_sequence="LADQVGVTVANLSVLKNNRAKAVRFTTLVALCDALDCQPGDLF
                     TAE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVCHLDQLLAEREMTLAA"
                     /leader_location="[8233:8287](+)"
                     /alternative_weights="4790.5"
                     /alternative_weights="4808.5"
                     /alternative_weights="4826.5"
     gene            complement(9033..9287)
                     /locus_tag="CORMATOL_RS10560"
     CDS             complement(9033..9287)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CORMATOL_RS10560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_034995888.1"
                     /transl_table=11
                     /translation="MRDSFKYLGSEWFLYVTTIGDRDGSLFTGLTMRHEPRDEDCQFSY
                     ELPTSLNPSQEVLVIILRFFLRFRTDLLLSGVSVVVFLI"
     gene            9286..9459
                     /locus_tag="CORMATOL_RS10565"
                     /old_locus_tag="CORMATOL_02549"
     CDS             9286..9459
                     /GO_process="GO:0050830 - defense response to Gram-positive
                     bacterium [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522761.1"
                     /locus_tag="CORMATOL_RS10565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02549"
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="WP_005522761.1"
                     /sec_met_domain="mature_ha (E-value: 1.9e-12, bitscore:
                     41.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNASTAVLDSTILDELDKELEAQIIKELEPEMFGLSRLLGNNGRW
                     CTITKECMPSCN"
     CDS_motif       9286..9387
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNASTAVLDSTILDELDKELEAQIIKELEPEMFG"
                     /locus_tag="CORMATOL_RS10565_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9388..9459
                     /prepeptide="core"
                     /locus_tag="CORMATOL_RS10565_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.00"
                     /molecular_weight="2524.9"
                     /monoisotopic_mass="2523.2"
                     /core_sequence="LSRLLGNNGRWCTITKECMPSCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNASTAVLDSTILDELDKELEAQIIKELEPEMFG"
                     /leader_location="[9285:9387](+)"
                     /alternative_weights="2543.0"
     gene            9488..9655
                     /locus_tag="CORMATOL_RS14310"
                     /old_locus_tag="CORMATOL_02550"
     CDS             9488..9655
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522762.1"
                     /locus_tag="CORMATOL_RS14310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02550"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_005522762.1"
                     /transl_table=11
                     /translation="MNQQPSNHDRVQNYSQDELRAMIENEEAVDGGTHPSTLIPISIAL
                     CPTTRCSRRC"
     CDS_motif       9488..9583
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNQQPSNHDRVQNYSQDELRAMIENEEAVDGG"
                     /locus_tag="CORMATOL_RS14310_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9584..9655
                     /prepeptide="core"
                     /locus_tag="CORMATOL_RS14310_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.50"
                     /molecular_weight="2400.9"
                     /monoisotopic_mass="2399.3"
                     /core_sequence="THPSTLIPISIALCPTTRCSRRC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQQPSNHDRVQNYSQDELRAMIENEEAVDGG"
                     /leader_location="[9487:9583](+)"
                     /alternative_weights="2418.9"
                     /alternative_weights="2436.9"
                     /alternative_weights="2454.9"
                     /alternative_weights="2472.9"
     gene            9717..9884
                     /locus_tag="CORMATOL_RS14315"
                     /old_locus_tag="CORMATOL_02551"
     CDS             9717..9884
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522764.1"
                     /locus_tag="CORMATOL_RS14315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02551"
                     /product="hypothetical protein"
                     /protein_id="WP_005522764.1"
                     /transl_table=11
                     /translation="MKKYTKQEWAYTTIGLALGVAVALSLGQGNYMMGALSAFFGICGY
                     LLARKSARKQ"
     CDS_motif       9717..9821
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKYTKQEWAYTTIGLALGVAVALSLGQGNYMMGA"
                     /locus_tag="CORMATOL_RS14315_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9822..9884
                     /prepeptide="core"
                     /locus_tag="CORMATOL_RS14315_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="2193.6"
                     /monoisotopic_mass="2192.2"
                     /core_sequence="LSAFFGICGYLLARKSARKQ"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKYTKQEWAYTTIGLALGVAVALSLGQGNYMMGA"
                     /leader_location="[9716:9821](+)"
                     /alternative_weights="2211.6"
     gene            10001..12601
                     /locus_tag="CORMATOL_RS10570"
                     /old_locus_tag="CORMATOL_02552"
     CDS             10001..12601
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005525272.1"
                     /locus_tag="CORMATOL_RS10570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02552"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_005522765.1"
                     /sec_met_domain="DUF4135 (E-value: 8.2e-58, bitscore:
                     191.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.8e-14, bitscore:
                     46.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSEFPNYYHVLSKSFKKTLLNRLTSADLPVTGTLIDDANNWFLS
                     RSAEFAQRALIDAFHAWRETTGYPDNAESSTAYDDFNRLLLDPNQRTTLVNDRFPKLGQ
                     LQERVFSYSVDAVVEAIERFYEDRPHLAMLNVKADDTIVSLGFHGEETHNHGRTAIVII
                     TDSAVVVYKPRSGMGEIAIDMVCRHLGAAPFSLVAPTIDIGDYCWQLFINPPATGEVDV
                     PAYMRAAGTLLAACHILGTTDLHVDNICCSSAGLPTIIDGETALQFRLPAGLNLDATDV
                     LASGMLPTVLSRSEFWRHFSGLNFFPHEKTATCVKHAVTDSGTDAVAFLRVSYQHPRPP
                     IVADLQNIDPAQAMGILIESFEKARVQAALSPTLAAYVRDMERVLRWRQVLRATGTYQS
                     FLEASLMPAALAGLDDPLTLLDKGPRGMVDGPTIGVQERRQLADGDVPLFQMDATGKVY
                     DGAGHHVGQASFTDRFSLPSSRLADFTSIAGPAYAQVLDANAHALTLHQPLDTVARVTE
                     PDMRQEILKKSTALPDSGGDRWLCFGIGDEDLTIEAQSISFLMSDGTSWALSDADELQN
                     RWEEFVREAPEFPANFVGFGPGTSLLVTQKAVGDATIVDKLPNVMASMDTTTDFLGGID
                     AALAALAHVTADVNPQPIVKSAMTFIGHQLQAAQPETNAGIAHGAAGLLLGAHGLVEFS
                     RARNLVVPDTIRRSMDTIADGIAKTALTMLTDPNITNGLAWCNGASGIAGALAITGHLA
                     HYPGLVDTYLTATQAKIAEPASDDDQVGIDVSLCHGLAGTLSTLQLLRDFGYADPKVVD
                     KFHAYVEHIALTAPICFGYPNNIHDMGYLNGLGGTYHALYPENHGSIRPLFAGN"
     gene            12629..14749
                     /locus_tag="CORMATOL_RS10575"
                     /old_locus_tag="CORMATOL_02553"
     CDS             12629..14749
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522766.1"
                     /locus_tag="CORMATOL_RS10575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02553"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_005522766.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.2e-19, bitscore:
                     62.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYQLFLQSRSAECGLACAAMILRRLGIDTDLHRLRTQYEVGRDG
                     MSTTAIRFLLLDFNVPSFQHKGRVRVIGEALKQGKQVMVHVDGDHFCLVESVDSRWVRL
                     ADPGRGRVKMSREDAIRKIGRTWWIMPDSGMSTAFRRARLMCRDLRTSPSLRIVKRTLV
                     SRPWLLLGVFALSLTLLAASGGAPLVISALVNSLQGKSAAPTQATALMLAAAIVTFIGL
                     AVGRTLVEALLLKVTSRELSIEGIRRNMGAKLESFSTHSPGEMMYSLGSVSMVSTGLFT
                     NGVTTAFNALTAITLLGVVAFLWPLMALVLVLVFFLLIGVFTLTVAKITQYGSEEASAG
                     GALSSQQLEIIVTMTPIRMTNSMDSFFDKWSVANERFLSATTKKAVWSGIGGATTMALT
                     VFGPLIPLVLSTLFPDSVSDLGAVVASSGLFSVFISAISQVFTGVTGLAGVQASIDRVD
                     DLLHMQQDPIGTEDPGCATPITTHQASYHYPGAAKNSLDKLDFSIRCGTHNTIVGASGS
                     GKSTFARLITGLVQPSSGSIRINGIDVADMSPEARARHIGFAPQENYLVSGTIRDNIAF
                     GRDISDKEIWAALKITQMDSVVRELPLKLSTPVGDMGSAFSGGQRQRFALSRAIAGKPS
                     LLVLDEATSAVDVPTERAITAALRDLNMTLISIAHRPTAAGPDDTVLRFTEDGTIVTES
                     PDYLKNLMESRG"
     gene            14756..15676
                     /locus_tag="CORMATOL_RS10580"
                     /old_locus_tag="CORMATOL_02554"
     CDS             14756..15676
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522767.1"
                     /locus_tag="CORMATOL_RS10580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02554"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_005522767.1"
                     /transl_table=11
                     /translation="MTTATTTATKISVSHLYKRYGSHQVIDDVSFDVQEGQVTLLAGPN
                     GAGKSTLLRMICGLDTIDKGDITIMGRHYSQLSDPKHTIGALLDATWLDTALTAEQNLR
                     VLADLAGIHRRRVANCLEMCGLTSVAGRKVSDFSLGMRQRCGIAAALLGDPELLILDEP
                     VNGLDPAGMRWLNDLLESHTQAGGTTLLSSHFLADSELIASRVVILGKGKTLWEGSLAE
                     LTGGARHTVFASYANDLIASQLHAMYTGLEITPLADGKVQVNVPPEDVSIAARIAEVDL
                     THLTVSRITLAEAFEQISEGQVEFQ"
     gene            15673..16593
                     /locus_tag="CORMATOL_RS10585"
                     /old_locus_tag="CORMATOL_02555"
     CDS             15673..16593
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522768.1"
                     /locus_tag="CORMATOL_RS10585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02555"
                     /product="ABC transporter permease"
                     /protein_id="WP_231289038.1"
                     /transl_table=11
                     /translation="MSTTHSASRITSRTTTRSIRRSSVHPAAHPMPHPSKPAHASAFAA
                     TQPPLLRALRGEWSQLRFDAAGFYILLFTTVITVAWSAASSNLVIRYGGEDAAPSARAA
                     ISGVFQFAMYGLFIWIARYLLREERTGFAKLKLLSLPNRFAIWVAKWVWLTIIAIASMM
                     VMAVLSTAVTLGSLALTDQPWQRFVGASAAEYLKLGVMITIIAVGTVAFGVAVAIFTNN
                     LSSALTMLFMWVLVIEGMLNGADESTRILYSLLPFKNGTRVFENPPMEWFMWNSTVSVG
                     YFLVVTIGLAALAIAFNKSKMTRDE"
     gene            16608..19445
                     /locus_tag="CORMATOL_RS10590"
                     /old_locus_tag="CORMATOL_02556"
     CDS             16608..19445
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522769.1"
                     /locus_tag="CORMATOL_RS10590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02556"
                     /product="DUF4135 domain-containing protein"
                     /protein_id="WP_005522769.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-26, bitscore:
                     88.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLERAIADKLLARLWSVAGPVRDIPPERFVSEVRNRTADFLTQI
                     PIELRRAASDAVSDCLGRIIAGNLSRADFAAAMHDQLLKIDEVGEWPQSEVVADAAGGQ
                     WRNVVAQIAGRWYNDLAVASKYRVRSNSALAIRLVMAHRHVGAAAARLEQRIAEELPDT
                     PNRVVLGLGDAHSRQQTVARVEFADRQLIYRPHSMATDQVIADICRLVGAPEPPHAFDM
                     GDHGWSEFLTAGPGVTDEAEFYAAVGAWAAVGYLFNANDLHNENFITVGNTPRLIDLET
                     FFQPEFSFLMAPNNRRWANSVLPMGVLPYRIGNGPDSIDVGLVRSRPTPGARHPFPSFM
                     VRTLDDGSRTFIKEDTLPADPEGTVFLGTTIPEIDRVKDQVKSAFIDTARRIVDKLDEV
                     RKIVAAARGIRTRVVLTPTFRYAQVLATAGHPAIADDPFLFTLACAQISLWGNDGVWRS
                     EWAGLMNDEIPLFTMGMTDTEVVLGDGAPLPFPQEKPVASASPAAHLESKLADATADGL
                     AEQCRWLETSFVGRYPENRIHAATDSARNMSHPRSKLVSHIVNMVLQAAGANDEAVFGT
                     DFLSATVGEEFDRNWQVGPSNDDFYGGSAGTLYFLAHLMQHTYRQWVPSDQIEQLLEKA
                     VAGMVTATTPEPPRADYPTGLCTGSSGLLLTAVACGDAIGWVSGGREHIARQCANGAIA
                     VATHARNANLDDINVDAINGLASQLRAYAEIAEYLPEVRPNLRELARVTRRVTRKWLRN
                     YPESPDDAGYAHSTAGVLDAYLAASHLCGATVDTGLVEQQVQAILAAIHATGNVSQGWC
                     HGMAGFGFLAAHLCDHIDTRAAGESLLSAIRPGLLAPVDHLGLSVCHGVAGLAESLMSL
                     YTATGDEEILDRARYLIDEAIPADLVGDGLTKENYSVSLMCGVAGVGQLLLSAPIVAAP
                     WHPVERMNVLWQKTA"
     misc_feature    19682..19697
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.86"
                     /tool="antismash"
     misc_feature    complement(19683..19696)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.97"
                     /tool="antismash"
     misc_feature    complement(19713..19728)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: strong, score: 27.48"
                     /tool="antismash"
     misc_feature    complement(19787..19802)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.48"
                     /tool="antismash"
     gene            19819..20949
                     /gene="dnaJ"
                     /locus_tag="CORMATOL_RS10595"
                     /old_locus_tag="CORMATOL_02557"
     CDS             19819..20949
                     /codon_start=1
                     /gene="dnaJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522771.1"
                     /locus_tag="CORMATOL_RS10595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02557"
                     /product="molecular chaperone DnaJ"
                     /protein_id="WP_005522771.1"
                     /transl_table=11
                     /translation="MAAKNEWVDKDYYADLGVTSSASDADIKKAYRKLARENHPDSHPG
                     DAIREEKFKKVAEAYDVVGDPTRRKEYDEFKEMLRVGGGFRGGGQSFQDFSDIFGGGRS
                     TGGFSDIFGGSWGATRRSARPTRGSDVETEITLDFREAAKGTTLPVQLTGDAPCAACHG
                     SGSRTGATSACKNCNGTGYVTENRGAFAFSAPCPDCDGTGKVITDPCPDCRGTGTVRRS
                     RSITVRIPAGVVDGQKVRLAGQGEAGPHGTPAGDLFVTVHVRPDKVFTRDGDNLEVEVP
                     VSFGELALGGTVSVPTLEKPVRVRIPAGTPDGRVLRVRGRGVPKRDGSFGDLYVKVKIR
                     VPKDLTDDAKDALRNYMEAEKHMGFDPRATWAGNES"
     gene            21001..21411
                     /locus_tag="CORMATOL_RS10600"
                     /old_locus_tag="CORMATOL_02558"
     CDS             21001..21411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005522773.1"
                     /locus_tag="CORMATOL_RS10600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CORMATOL_02558"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_005522773.1"
                     /transl_table=11
                     /translation="MSKNKNQESMGEVFVISVAAELAGMHAQTLRTYDRMGLVTPQRTS
                     GGGRRYSREDVELLRTVQRLSQEDGVNLAGIKAIIQLKKENEELRTKLQEARAENEVLK
                     HNRHRGEIVHVPRSTAVVMWESRRGPRRKKQS"
ORIGIN
        1 gtggactgtt agggggtgta tcataatgag tgaatggcca acggtgaaac tgggggaggt
       61 tgcagaacag accaaccata gagttggtga gttggatgta ccaatttatt cagtcactaa
      121 atatgatggt tttgtcccaa gcagtgaata ctttaagaag cgagtatttt cgatggatat
      181 tcgaaagtat aaattgtgta ctgcgggaga ctttgcttac gccactattc atttagatga
      241 aggctcaatt ggcatttctc cggtaaaatg tggcatcagt ccgatgtaca cgacatttcg
      301 gttgaattct ttaaatatct ctcctgatta tttgttacgg tatctgaagt ctagcagggc
      361 tttgacgcaa taccttactt tagggtcagg tagtgcagaa cgtcggaaaa gcattaaatt
      421 taccgatttg cgaaaaatgg agatcccctt ccctcctctc ggggaacaga atcgtattgt
      481 agggatcctt ggtaaaacaa ccggggccat ttcttctgtt caaaaacaaa tcgaacaggc
      541 aaagaaattg cgtagttcaa tagttgggat ggccagtaaa atggcggtag agctacgtgc
      601 tatttctgaa tatttcgaca ttaatcctcg gcaacctcgg aatattccag ataatgcccc
      661 cacttctttt gtacccatgg caaatttaga cgaaactttt ggtatctctc caattactag
      721 ccggttctct gagcataaaa aagggtacac atattttgag aacggcgata ttttattagc
      781 taaaattact ccttgcttcg agaatggaaa atctgcaata gcaaaactct cgacccaaat
      841 tgggcatggc tcaacggaat ttcatgttct gcgccataaa aatcacatgc atcaagatgt
      901 atgtctatca cctttgctgg ttgctgcgat tttgaagcaa ccgtcttttc tgaaacctgc
      961 tgaaaacttt atgcgtggaa gtgcgggcca aaagcgtatc ccagtctctt atatcgcatc
     1021 attgaaagtt ccagtgctta agagtgttga cctggaaaag attgatcaat cattagagat
     1081 agtggaagct ttattgaatc tctaccaccg caagctttcc cttctccaag agttgcaaaa
     1141 atcgttggct acccgggcgt ttgcgggtct gctttaggcg tcgaaaagct tgggtataac
     1201 tagcgtgaaa ggaatacgat gattacgccg cagccatcca acttcgcatt cattggccgg
     1261 gtgtggccgg agctgctcat tcattgccgc aacgcggaac agtcggcagt cagtaacccg
     1321 cgggtggcag gtatcgaagc gcgcttcacg ctcgaacgcc tggtcgatca cattgtcgaa
     1381 gcgtatgggc tgcgtagcgt cagtgattgg aacctcaatg acaagctcaa ccaccgatcc
     1441 ttcaaggatc gtgtcaacca gcggattcat gacaaaatga atgtgctgcg gcgtttcggt
     1501 aacgatgccg cccacaaccc ggatcatatc gacccggagc gagccgtgcg ggcaatcgga
     1561 caactgttcg atattctcgt gtgggcagct gtcaacgttg cccgaccgcc gctggaacgc
     1621 accaagctgc ccaccttcga ccgcagcatc gtctataacg cccccaagca gcgacaacga
     1681 agccaacagg aaatcgctaa gctcaaccag caactccaga aggctgtcga cgaaatcgaa
     1741 accacaaaac tcctgctcac cgagcgggaa gaaacctggc ggcaggaacg caaggcacac
     1801 cttgaccaaa tcgctgcctt caaggggcaa accgaagaac tcgcccgggc ccgcgaccag
     1861 ctggaagccg aactcgcgca gcttcgggcc gacattgccg ctaacacccg cagcatcgat
     1921 accagtaata actttgccat tagtgaggcc gagacgcgtc gggacctcat cgaccccgcc
     1981 ctcgccgaag ccggtttcaa cgtggcgcgc ggtaatctca aaacggaatt ctgtttggcc
     2041 gacggcaagg gtgttgtcga ctatgtgctc ttcggtgatg acggtcggcc ctacgccatt
     2101 gtggaggcca aacgtgcagg taaagccatc gacgccggcc ggcaacaggc ggaatattat
     2161 gcagacgaac tagagaaaca atttggattg cggccaatca tttactatac caatgggcac
     2221 gaaatccggt tgttggacga tgctgcaaac ctccccggga ttggtgccgg tgctgggtat
     2281 ccatcgcgcg cagtcgaagg gtatgctacg aaagatgaat tgtatgcgat gattcgccgg
     2341 cggactcagc ggcaggacct caacactgtg agcgtcgata cgcaaatagc tggcaggccc
     2401 taccaaatca ccatgcttca agccgtcgcc gaacgatttg gggcggggca tcggcgggcg
     2461 ctgctggtca tggcgaccgg caccggtaaa acccgcaccg caatcgccct ggtcaaacag
     2521 cttgcgcagg ccggctgggt gaaaaacgtc ctcttccttg ctgaccgcaa aagcctggtc
     2581 aagcaggctg cggaggcgtt cagcgagcac ctgcgcgaca tgcccgtcgt ggaccttctg
     2641 cgcaaccagc acggcaccgg ccaggtctac tgttccacct accaaaccat gatgaagctg
     2701 ctcggtagcc ggttcggcac ctaccagttt gatctcatca tagttgacga agcccaccgc
     2761 tccatttatc gacgttacag ccgaatattt gactacttcg actcgttact gctggggctc
     2821 accgccacgc cgcgctgcga cgtcgaccac aatacgtacg cgcttttcca gcttaacgat
     2881 ggccaaccca cagccaacta ctctctggac gaagccgtcg acgagggata tctggtcccc
     2941 ttcaaagcct ttcaatgctc ctctgtcatc ctccgcgacg gcgtggccta caaagacctt
     3001 agccccgaag agcagcaaca atgggaaaac caggactggg ggatcgacga cgatggtctt
     3061 ccgctcgaca ttcccctgga ggtcgagtcc gaagaaatca acctcaaact gtacaacaaa
     3121 gacaccatcc gaaaagttgt cggccaagtc ctctgtcacg gcatcaaggt ggctggcgct
     3181 gaccgaattg gaaaaaccat cttcttcacc cgcagcaaga agcatgccca actcgtttgc
     3241 gatatcatcc atgagacaaa cccgcaggtg cgggcggctg tcatcactca tgaagtctat
     3301 gacagcctcg atctcatcga ccgattcaaa gcctccggca aaggttccct cgacgttgcc
     3361 atcagcgtgg acatgctcga taccggtgtg gatgtgcctg ccgtagttaa cctggtgttt
     3421 ttcaaacctg tgtactccaa caccaaattt tggcaaatga tcggccgtgg cacccgattg
     3481 gcgcccaacc tgtttggcaa aggcctagac aaacgagaat tctacgtctt cgactactgt
     3541 gacaacctcc gccgctttga agacgccgag cacatcgtgt ccaccactgg cagtcaacaa
     3601 cgtcccctat ccgaacgtac gttcctgaag cggatagagt tagcttcact actgcccgct
     3661 gacgacccaa cccgagctga cctcgtgtca gggctacgga atcaactcca aaccgtcccc
     3721 atcagtagcg tacttgtgcg acccgaagac cgcgctgaac tggaacatta cttgtgcgct
     3781 gatgcctggg gatctggcac ggatatagaa tctgcaggta aactggcata tctccccttc
     3841 gctgatgatc ccgaagacga agaacaagcc aaacgattcg actatctcat gctcaccctg
     3901 caactagccc tcgcccgggg cgaagcctta cccacgcgcc accgggatcg agtgaccaac
     3961 atcgcgcgcc acctattgag taaaaccaat gtgccccgtg ttgcggacgc tgccagcaca
     4021 ctcgaacact atagcgaaga cctgtggtgg gaaggcatca ccattgccga cctggaactt
     4081 gctcgccgaa ccctacgcac cctggtgcaa ttcatagatc ccggttaccg cagtgaggtg
     4141 gttctcgaca tcgaagacga actggccgaa cccgcagagt tcaacctacc caccgaaacc
     4201 gctaacctga gctacagcag tgttgaagac caactcagag aagttctcga aaaacaccta
     4261 gacgaccttc ctatccagcg gctacgcaaa atgaagcccc tcaccgccat ggacctggcc
     4321 gccctggagg agatcattgc tggtgtggaa ggtgtcgacg aatttcgggc ccgcatcggg
     4381 gaccaaagca ttgttggatt cgtgcgcagc cttatcgggc tggaccagga agcggtccag
     4441 gagcaattcg ccgacttcct cagccgctcc aacctcaacg ccaagcaaca agaattcctg
     4501 cgtcgcatca tccgggtgct cgctaaaacc ggttcgctga ccataggcca actgttcgaa
     4561 gaacccttta aagatcttgg caatgtcttt gacgtcttcc ccggcgacga taccattgtg
     4621 tacgacctga aagatcggtt agaccgaatc ggcaaaatgg acgtggccgg tggtggggta
     4681 ggcgaagccg ggtagggggt agcgaggcct ggggtggctt ggggcttgcc aggttttcgg
     4741 gtcggtagcc gatgtgaaac tctagcttag cggtgatgca gccttgtgag gttgagggta
     4801 tcggttctgc tgagctggag ttctggtttt gggcgtttcc ggttcctggc tgtatggagc
     4861 agcatttttg aaactacagc tcagcacttg cgaagcatgg ctgtggcggg gagtcggttg
     4921 gccatgcgct ggggctgcaa gtttggtggg ctggggtttg ttggtgcagt tatgccgtgg
     4981 agcttgcttt tctataagtc ccagcccacc aaacctgaag ccccgttagg tatcaagttt
     5041 cctgagctgg agttctggtt tggggcgttt ccagctcctg gccgtatggg tgcagcattt
     5101 ttgaaactac agctcagcac ttgcgaagca tgatcgtggt ggggaaccag cgcgaaaaat
     5161 atgatctata ccacttgata ccggagttat gggtgtttgt gccggtagtg gcaattttgc
     5221 atgcgatggt gggggagagg gcacacttgc ggcatatcga ataacgatat aacatattga
     5281 ataacgatat atcgaaaaac gatatgcgga tgattgtcga aaggaaggaa atcatgaaca
     5341 tcatgaacga cacaggtaag ggtgcaacgg cattgcgggc tagcctggga ttccctctgt
     5401 atgtgaagcc tcggtcgctg cggggtccgt cgcaaagctt ggtgcgcaac agtaggggca
     5461 actcgaaaaa caattgcgca aaaccaggcg ggttgggtcg ccccaaccgc ccgtcgtcag
     5521 gcactgcgac tcgtcgcgga agggctactg ccatgaaagt cgtcaaaact ctcaccatca
     5581 tcattgcggt gatcgccgtt ctggtcggcg ccatcacctg gttctttggg ccaagcttgg
     5641 gggtcgcgct gctcggccgg ccgatcctca tggtttccac gccgcaccgc tacggacagg
     5701 ccgccatcga cattggccgc agctttgcga tctacgcgga cactccgcaa gccaccgcag
     5761 cctacgagga agccaaagcg gaaattgcga acgtccattc ggttgaggaa acctacccga
     5821 tcatcaagaa atacctcaag gtggccggcg ggaaacattc caatttcctt tcgccggaag
     5881 acaacgcaac cagcgatgac ttgggtaatg actccccaac cgtaaccaag aatgacaaca
     5941 tcgttaccgc catgcttccg agtctgaatc tcgggccggt cggacaaaaa tatgcggaca
     6001 tacttgcgaa cgggttggcc gaaaacgttc cgaattcctg tggtgtcatc cttgacctcc
     6061 gcaaaaacga tggtggcgac atgggtccca tgcttgccgg cgtcagcgga ctcctgcccg
     6121 atgggaccct cctgagcttc aagagcaaaa actcgaccag cccagtcacc ctcaacaacg
     6181 gcagcatctc cggcggcggc acacccacta ctgtggggcc gaaagacaag ttccgggtgc
     6241 cggtcgccat cctcaccagc aacgttaccg ccagctctgg cgaagccacc ctcctcagct
     6301 tccgcggcct ggaaaacacg cgcacatttg ggcagcccag cgccggctac gccagcggca
     6361 acctgattat tgacatgccc gacggcgccg gcttgatggt cactactgct aacgacatgg
     6421 cccgcaccgg agaagaattc tccgaagacc cgattgcgcc ggacgtgtcg accgaccggc
     6481 cggaacaggc agcaaccgag tggttgcatt cacagtgtgg ccaatgactg gccttgccat
     6541 tcgccaataa accatccgag gcttattcac aacggtggaa agtacaccca cacttcccac
     6601 caatcgaata agtctcgaac tatattcacc agccatgagg gtaagagcat tcacgtagaa
     6661 tgaacataat caagacgaat atatgctagt taggcagata aaataatgtg ttacccagcc
     6721 caaggaggta caacaatatg aaattgggca acattttccg aggaccaaaa tggcccagag
     6781 ccgccgctga atttatcgca acacattttg cggacaagag cgtgacagaa ttctttgacg
     6841 aaccacgctt cgaacgattc ctttatctcg ccaaaaccga gacatgggtt gaagccgccc
     6901 gggaatatcg tgatgtcacg ggcgaagaca ttcaatcaag cattattgct gccgaggtgg
     6961 cccgccggac gttccggtaa gcgagagcgt gggggagggg gtttcaagct ggggagggga
     7021 gcgggcaaag cttgctgaaa tccgctgttg gtgtgggttg cgcatgtggt gggctggggt
     7081 ttgagtaact tgtgaccttg tgtgtcctga tgacaccgac aaaccccagc ccaccaaact
     7141 tgaagccttg caggtttgga gatagtggtt ttgctgagct ggagttctgg ttttaggcgc
     7201 tttgggttct tgggcgtatg ggggcagcag gtttgaaact atagctcagt acttgtgaag
     7261 cgtggctgcg gtggtgagtt tgtcggggct gcaaacttgg tgggctgggg tttgccggtg
     7321 ctgtcaaggc attcgagaga acgacctatc caagtcccag cccaccaaac ctgcagcctc
     7381 gttaggtagc aagtttcctg agctggagtt ccaacttgca gccggtaaga ccagcagcaa
     7441 cgaaaaacca agctgtgctg ctctggagtt gtccaggtac agtcctgcag ccttccagct
     7501 atccttgcac cctgtatccg cccctgaaac cggcttgaac ctacatgggg gaggactctt
     7561 gcggcatatc gaaaaacgat ataacatatt gaataacgat atatcgagaa acgatatgct
     7621 tctcgcgcag ataagcggga attgcaggaa gggcaaggac tacgtcatgg acgttgacaa
     7681 aaaagatcgc aacgaaatcc tcgtcgccat gattatctac acactgatgc tggtgctgct
     7741 gggccgtcgg ctactcgatc tcgtgatctg gcaccggatt ccccactcct tcggggtgct
     7801 gctcgcggag cgggcagatg agggcatgat cccgctctcc ctggctgact ccgtcgcaaa
     7861 gtcactgctc attagtggtt tcctgctgtc gctcctgggc attgttgtgg tggccacgac
     7921 gctgattctg ctggcccggc agctgcttaa aggccagttc ttcaccgcat ataatgtgaa
     7981 atgcttcact attgggtcgc tgtcgcttgg tgtctatttc ctgggcgttt tcgtgcagaa
     8041 tatgggggcc aatgagatgg ctgcaaagct gaatttgcgc agctggtttg actactctga
     8101 ggcacaaagc ttggattata ttgctatgtt tctgttcgta gaaacattgg tgctgttagc
     8161 ggtagtgatt cgccgcggga tctctatgca agaagaccag gaagggttga tctgattggt
     8221 aaagctacaa agagtggtct gccacctcga ccaactcctg gccgaacgcg aaatgacgct
     8281 tgcagccctc gctgaccagg ttggggtcac cgtcgccaac ctatccgtgc tcaagaataa
     8341 ccgtgccaaa gccgtacgat ttaccacgct cgtggcgctt tgcgacgccc ttgactgcca
     8401 acccggtgac cttttcaccg ccgaataacc accaccaatc cagctcgcca agcttaacga
     8461 tcggtgaaga aacccacggc tagcggctgc gatgcgagaa cctcggaacc caaaaccata
     8521 attagcacct cttctacttt tctatgcttg tggcgatagt agataaattg ctactaacga
     8581 ggggatatgg gatccattgc aatctttcgt gccggaaaac atcctaggca aattcatgca
     8641 atagaaattg aatcttacta taagatatct gcgctattgc ttgctcatta gtgcaaattt
     8701 ggagcagtat tattctcttt agcggggagt tttaaactca aatttagtaa aatttaagta
     8761 tttttaaccc ggtttcgacc catcttgccg cgggatgcta gcaaaagtga tactgccata
     8821 atgttgtgct gcacttctgc tgatattgcc gaaaaaagcc cccgatagta tgtgcgcctg
     8881 tcaactaccc ctatatggtt acccctagtg ctctgtgaaa aatccctgct caacggcttg
     8941 taatcggcct aaattacccc caaagagata gcagaactga tatatatcaa atctgctatg
     9001 gacattgatt gtcgtgttcg ttattatcga aatcagatca agaaaacaac aacagaaaca
     9061 ccggaaagga gcaaatcagt gcgaaaccta agaaagaatc gcagaatgat taccaatact
     9121 tcttgactag gattcaatga agtaggtaat tcataagaaa actgacagtc ttcatccctc
     9181 ggctcgtggc gcattgtcag gcctgtaaaa agcgagccgt cacggtcacc aatagtcgtg
     9241 acatacaaaa accattcact cccgagatac ttgaaggaat ctctcatgaa cgcctccacg
     9301 gccgtgcttg acagcacaat cctcgatgag ctcgacaaag agctcgaagc ccaaatcatc
     9361 aaagagctgg aaccggaaat gttcggcctc agccgcctgc ttggaaacaa cgggcgctgg
     9421 tgcaccatca ccaaagagtg catgccctcc tgcaactaac acaacaccca agaaagaggt
     9481 tttcactatg aaccagcaac cctccaacca cgatcgtgtc cagaactact cgcaggatga
     9541 gctgcgagcc atgatcgaaa acgaagaagc cgtcgacggc ggcactcacc ccagcaccct
     9601 catccccatt tccatcgctt tgtgccccac tacccggtgc agccggcggt gctaaagagt
     9661 aggcttggtg ttccacggaa actgctgcaa tcctgagaat ctgaaggaga aaaaccatga
     9721 agaaatatac caaacaagaa tgggcataca cgaccattgg cttggcgctt ggcgtcgcgg
     9781 ttgctttgtc ccttggccaa ggcaactaca tgatgggagc gctctccgca ttctttggaa
     9841 tctgcggcta cttattggct aggaaatctg cccgcaagca gtagtttcct gcttcgaggg
     9901 cgcaagccac caccattaag ggcccagtta cttccactct aggtaactgg gccctttttc
     9961 tatcctcaaa tacataacaa cagacttaaa gggattaagc atgcattccg aatttcccaa
    10021 ttactatcat gtgttgagta aatcgtttaa gaaaacgttg ctcaaccgcc ttacctccgc
    10081 cgatctcccc gtgaccggca cactcattga tgacgccaat aactggttcc tgtcacgaag
    10141 cgcagaattc gcccagcgtg cgcttatcga tgcctttcac gcatggcggg aaaccacagg
    10201 ttatcctgat aatgccgaat ccagtactgc atatgacgac ttcaatcggc tccttctcga
    10261 ccccaaccag cgcaccaccc tggtgaatga ccggttccct aagcttggcc aactacaaga
    10321 aagagtgttc tcctatagcg ttgatgcggt tgttgaggcc atcgagcgtt tctacgagga
    10381 tcgtccccac ctggccatgc tgaatgtcaa ggcggacgac accatcgttt ccctgggctt
    10441 tcatggcgaa gaaacccaca accatggccg caccgccatt gtcatcatca ccgactcggc
    10501 agtggtcgtg tacaagcccc gcagtggcat gggagaaatc gccatcgaca tggtgtgccg
    10561 tcacctgggt gccgccccat tctcgctggt agcgccgacc attgacattg gggactactg
    10621 ttggcagctc tttattaacc cgccggccac cggtgaggtt gacgtccccg cctatatgcg
    10681 ggccgccggc acgctgctgg ccgcctgcca tattctgggc actaccgacc tgcacgtcga
    10741 caatatttgc tgctcctcgg ccgggcttcc taccatcatt gatggtgaaa ccgctctcca
    10801 atttcggctt ccagctggcc tgaaccttga cgcgaccgac gtgttggcct ccggcatgct
    10861 gcccaccgtg ctctcccgta gcgagttctg gcggcacttc tctggactaa acttcttccc
    10921 ccatgaaaag accgcgacat gcgtgaaaca tgccgtcacc gattccggta ccgatgctgt
    10981 ggccttcctg cgggtcagct atcagcaccc ccggccgccg atcgttgcgg atctgcaaaa
    11041 tatcgatccg gctcaggcca tggggatcct catcgaaagc tttgaaaagg ctcgggtgca
    11101 ggcagcatta tcgcctaccc tggctgccta tgttcgggat atggaacgcg tcttgcgttg
    11161 gcgccaggta ctgcgagcca ccggcaccta tcagtccttc ctggaggcat cactcatgcc
    11221 ggcagccctc gctggcctgg atgatccgct cacgctgctg gacaaggggc cgcgcggtat
    11281 ggtcgacggt cccaccatcg gcgtgcagga acgacgtcag cttgccgacg gtgacgtgcc
    11341 gttattccag atggatgcca ccggaaaagt ctatgacggt gctggacatc acgtgggcca
    11401 ggcctccttc accgaccggt tctccctgcc tagcagcagg ctggccgact tcaccagcat
    11461 tgctggcccg gcctacgcgc aggttctcga cgccaacgcc cacgccctga ccctccatca
    11521 gccactcgat acggttgcgc gagtcaccga gccagatatg cgacaagaga ttttgaaaaa
    11581 atcaactgcg ctacccgact ctgggggtga tcggtggctc tgcttcggta tcggtgacga
    11641 agatctcacc attgaggctc agtccatttc cttcctcatg agcgacggca cctcctgggc
    11701 gctcagcgac gcagacgagc tgcaaaaccg gtgggaggaa ttcgtgcggg aagcccccga
    11761 attcccagca aacttcgtgg gattcggccc cggaacctcg ctgcttgtca cccagaaagc
    11821 ggttggcgac gctacgatcg tcgacaagct gcccaatgtg atggcttcga tggacaccac
    11881 caccgatttc ctcggcggca ttgacgcggc gcttgccgca ttggcgcacg tcaccgccga
    11941 tgtgaacccg cagccgatcg tgaagagcgc catgacgttc atcggtcacc agctgcaggc
    12001 cgcccaaccc gaaaccaatg ccgggattgc ccacggtgcc gccggtctgc tgctgggggc
    12061 acacgggctc gtggaattca gccgcgcccg aaatttggtc gtacccgata ccattcggcg
    12121 cagcatggat accatcgccg acggtatcgc caaaaccgca ctcaccatgc ttaccgaccc
    12181 aaacatcacc aacggcttgg cctggtgcaa cggcgcctcc ggtatcgccg gcgccctcgc
    12241 catcaccggg cacctggccc actatccggg cctggtcgac acttacttga ccgccaccca
    12301 ggcgaaaatc gccgaacccg ccagcgacga tgatcaggtt ggcatcgacg tttccctctg
    12361 ccacggcctg gccggcacgc tgagcaccct gcaattattg cgtgatttcg ggtacgccga
    12421 cccgaaggtt gtcgacaagt tccatgccta tgtggagcat attgcgctca ccgcccccat
    12481 ctgcttcgga tatcccaaca acatccatga catggggtat ctcaacggcc ttggtggaac
    12541 ctaccatgcg ctctaccccg aaaaccatgg gtcgattcgg ccgctctttg ccggaaacta
    12601 gagctgcgat gaaagggaag aaattcgtat gaagtaccaa ttatttctgc aatcgcgctc
    12661 cgccgaatgc ggcttggcat gcgccgcaat gatcctgcgt cggctgggta tcgacaccga
    12721 cctgcaccgg cttcgcaccc aatacgaggt tggtcgggac ggcatgtcca ccaccgccat
    12781 ccggttcctc ctgctcgact tcaacgtccc atccttccaa cacaaagggc gggtccgggt
    12841 catcggtgag gccctcaaac aggggaaaca ggttatggtc catgttgacg gtgaccactt
    12901 ctgccttgtc gaaagcgtcg actcccgatg ggtgcggctc gccgaccccg gccgcggccg
    12961 cgtcaaaatg agccgcgagg acgcgatccg caagatcggt cgcacctggt ggatcatgcc
    13021 cgactccggc atgagtaccg ccttccggcg tgcccgactc atgtgccgcg acctgcgcac
    13081 ctccccctcg ctgcggattg tgaaacgcac tctcgtgtct aggccctggc tgctgctggg
    13141 tgttttcgcc ctcagcctca ccctgcttgc cgcctccggg ggtgcgccgc tcgtgatctc
    13201 tgcgctggtc aactcgctgc agggcaaatc cgccgcaccc acccaggcca cagcgctcat
    13261 gctggcggcg gcgatcgtca ccttcatcgg tctggcggtg ggccgaacac ttgtcgaggc
    13321 cctgctgctc aaggtgacct ccagggaact cagcatcgag ggtatccgcc gcaacatggg
    13381 ggcgaagctg gagtcgtttt ccacgcactc acctggggaa atgatgtatt cgttggggtc
    13441 ggtttctatg gtttccaccg gactgttcac caatggcgtc accaccgcgt ttaatgcgct
    13501 caccgccatc accctcctgg gggtggtcgc cttcctctgg ccgctcatgg ccctcgtgct
    13561 ggtgttggtg ttcttcctgc tcatcggggt tttcaccctt actgtggcta aaatcaccca
    13621 atatggtagt gaggaggcgt ctgccggtgg cgccctttcc agtcaacagc tggaaattat
    13681 tgtcactatg acgcccattc ggatgaccaa tagcatggat tccttctttg acaaatggtc
    13741 tgtggccaac gaacgcttcc tcagcgccac cacgaagaag gccgtgtggt ctggcatcgg
    13801 cggcgccacc accatggcgt tgaccgtgtt tgggccgctc attcccctgg tactgtccac
    13861 cctgttcccc gactcagtgt ccgacctggg ggccgtcgtc gcctccagcg ggctgttctc
    13921 ggtgttcatc tccgccatct cccaggtgtt taccggggtc accggcctgg ccggcgtgca
    13981 ggcttccatc gaccgggtgg atgacctgct gcacatgcaa caagatccta ttggcaccga
    14041 ggaccccggt tgtgctaccc ccatcaccac ccaccaggcc tcctaccatt atccaggggc
    14101 ggcaaagaat tccctggaca aactggactt cagcatccgg tgcggaaccc acaacaccat
    14161 cgttggcgca tcaggcagcg gcaagtccac gtttgcccga ctcattacgg ggttggtgca
    14221 accctcgtca ggtagtattc gaatcaatgg catagatgtt gctgatatgt caccagaagc
    14281 gcgtgctcgt cacattggct ttgcccccca ggaaaactac ctggtctcag gcacaatccg
    14341 ggataatatc gcctttggtc gagacatttc cgacaaagaa atttgggcgg ccctcaagat
    14401 cacccaaatg gactccgttg tgcgggaact ccccctcaaa ttgagcaccc ccgttggtga
    14461 catgggtagc gccttctccg gcggccagcg gcaacggttc gccctcagtc gagcaatcgc
    14521 cggcaaacca tcgctccttg tgctggatga ggccaccagc gccgtcgacg tgccaacgga
    14581 acgtgccatc accgctgctc tccgcgattt gaatatgacc ctgatcagca ttgcgcaccg
    14641 acccactgcg gctggacccg acgacaccgt tctccgcttt accgaggatg gcaccatcgt
    14701 caccgagtct cccgattatc tcaaaaactt gatggagagc cgaggttaac aacctatgac
    14761 aactgcaaca acaactgcaa ccaaaatttc cgtttcccat ctgtacaaac gctacggatc
    14821 gcaccaggtc attgatgacg tatcattcga tgttcaggaa ggccaagtca ccctgcttgc
    14881 cgggccaaat ggtgccggca aatctaccct cctgcgcatg atctgtggtc tagacactat
    14941 cgacaagggc gacatcacca tcatgggccg gcactacagt cagctctccg accccaaaca
    15001 caccattggg gcgcttctcg acgccacctg gttggatacc gccctcaccg cggaacaaaa
    15061 cctgcgggtt ctcgctgacc tggctggcat ccatcgccgt agggttgcca actgcctcga
    15121 aatgtgtggg ctcaccagcg tggccggccg caaggtttcc gacttttcac tgggcatgcg
    15181 ccaacgctgc ggcattgccg ctgccctgct gggggacccg gagctactca tcctggatga
    15241 gccggtcaac ggcctggacc cggccggcat gcgctggctc aatgacttgt tggaatccca
    15301 cactcaggcc ggggggacca cgctgctttc cagccatttt cttgccgact ccgaactgat
    15361 tgcctcccgg gtagtcattt tgggcaaggg caaaaccctg tgggaagggt cgctcgccga
    15421 actcaccgga ggcgcccggc atactgtgtt tgcttcctac gccaatgatc tcattgcgtc
    15481 ccaactgcat gcgatgtaca cgggcctgga gatcacccca ttggccgatg gaaaagtcca
    15541 ggtcaatgtg cccccagagg atgtgtctat cgctgcgcga attgccgagg tggatttgac
    15601 gcatcttacg gtttcccgta tcacccttgc cgaagcattc gaacaaattt ctgaaggaca
    15661 ggttgaattt caatgagcac aactcactct gcctcccgca tcacttcccg caccaccacc
    15721 cgatccattc gccgatcgtc ggtgcatccg gcggcccacc caatgccgca cccgtcgaag
    15781 cctgcgcatg cctcggcatt tgccgccacc cagcctccac tgttgcgtgc cctgcgtgga
    15841 gaatggtccc agctaagatt tgatgccgcc ggcttctaca ttcttctgtt caccactgtg
    15901 attacggtgg cttggtcggc ggcctcaagt aatttggtga tccgctatgg tggtgaggat
    15961 gccgccccct cggcgcgggc cgccatcagc ggagtattcc aattcgccat gtacggcctg
    16021 ttcatttgga ttgcccgcta cctgctgcgt gaggaacgca ccgggtttgc caagctgaaa
    16081 ctgttaagcc tgcccaatag gtttgcgatc tgggtggcca aatgggtgtg gttaaccatc
    16141 attgctatcg catccatgat ggtcatggca gtgttatcca ccgcggtcac gttgggcagc
    16201 ctggcactta ccgatcagcc gtggcagcgg ttcgttggcg cgagcgccgc ggagtacctg
    16261 aagctgggcg tgatgattac gatcattgcc gttggcactg ttgcgttcgg ggttgcggtg
    16321 gccattttca ccaataactt gtcttccgcg ctcaccatgt tgttcatgtg ggtgttggtg
    16381 attgagggca tgctgaatgg cgcggacgaa tccacccgga ttctttatag cctgcttccg
    16441 tttaagaatg gcacacgggt gttcgaaaat ccgccgatgg aatggttcat gtggaattcc
    16501 accgtaagcg ttgggtactt cttggtggtg acgattggct tggcagcgct ggctatcgct
    16561 ttcaataagt ccaagatgac ccgggacgag tagggggcgc gtggatcatg actctcgaac
    16621 gtgcaatcgc cgataagctt cttgcccgtc tgtggtccgt cgccgggccg gtacgggata
    16681 ttcccccaga acgtttcgtt tcagaagtgc gcaatcgaac ggcggacttt ttgacccaga
    16741 ttcctattga actccggcgg gcagcttccg atgccgtgtc cgactgtttg gggcgcatca
    16801 ttgctggcaa tctgtcgcgc gccgacttcg ccgcagccat gcacgaccaa ttgctgaaaa
    16861 tcgacgaggt gggggagtgg ccgcagagcg aggtggtggc ggatgccgca ggcgggcaat
    16921 ggcgcaatgt ggtggcccag attgccggcc gctggtacaa cgacctagca gtcgcctcca
    16981 aatatcgggt tcgtagcaat tcggcgttgg cgattcggct ggtgatggcc caccggcatg
    17041 ttggtgcggc cgcggcccgc ctggagcagc gcatcgccga agaactgccg gacaccccaa
    17101 accgggtggt tttaggattg ggggatgccc attcgcggca gcagactgtt gcccgcgtgg
    17161 aattcgcgga ccgtcagctc atctaccggc cccactccat ggccaccgat caggttattg
    17221 ctgacatttg tcggctggtg ggtgcgcccg aaccgccgca tgccttcgac atgggggatc
    17281 atgggtggag cgagtttttg accgccggac cgggagtgac cgatgaggcc gagttttatg
    17341 ccgccgtcgg cgcctgggcg gccgtgggtt atttgttcaa cgccaacgac ttacacaatg
    17401 aaaacttcat tacggttggt aacaccccgc ggctcatcga cctggaaaca ttctttcagc
    17461 ccgagttttc gttcctgatg gcgcccaata atcgtcggtg ggcaaactcg gtgctgccga
    17521 tgggggtgct gccgtatcgg atcggcaacg gacccgattc aattgatgtg ggtctggttc
    17581 gcagccgtcc cacccctggc gcccggcatc cgttcccttc gtttatggtg cgcacgcttg
    17641 acgacggctc ccgcaccttc atcaaggagg ataccttgcc cgccgacccg gagggcacgg
    17701 tgttcctggg caccaccatc cccgagattg atcgggtgaa agaccaggtg aaatcggcct
    17761 ttatcgacac cgcacggcgg atcgtcgaca agcttgatga ggtgcggaag atcgtggctg
    17821 cggcgcgggg gattcgtacc cgggtggtgc tcacgccgac attccggtac gcgcaggtgc
    17881 ttgccaccgc cgggcatccc gccattgcgg acgacccgtt cctgttcacg ctagcctgtg
    17941 cgcaaatcag cctgtggggg aacgatggcg tgtggcggtc ggagtgggcc ggcctcatga
    18001 acgacgagat tcccctgttc accatgggca tgacggatac ggaggtggtc ctgggggacg
    18061 gtgcgccgct gccgttcccc caggaaaaac cggtggcatc ggcgtccccg gcggcacact
    18121 tggagtcgaa gcttgccgac gccaccgccg atgggctagc cgaacagtgc cggtggctcg
    18181 aaacgtcgtt cgtgggccgc tacccggaga accgcatcca cgccgctacc gacagtgccc
    18241 gcaatatgtc gcatccccgt tcgaaactcg tgtcccacat tgtcaacatg gtgttgcagg
    18301 ccgctggcgc gaacgatgag gccgtgttcg gcaccgattt cttgagcgcc acggtggggg
    18361 aggaattcga ccgaaactgg caggtcgggc cgagcaacga cgacttctat gggggaagcg
    18421 ccggcacctt gtacttcctg gcgcacctca tgcagcatac ctaccggcaa tgggtgccta
    18481 gcgaccaaat cgaacaatta ctcgaaaaag cggttgcggg catggttact gccaccactc
    18541 cggagccgcc ccgagccgac tatcctaccg ggctctgcac cggcagcagc ggtctgttgc
    18601 tgaccgctgt ggcctgcggc gatgccattg gttgggtgtc cggcgggcgg gaacacattg
    18661 cccgccagtg cgccaatggc gcgatcgcgg tggcaaccca cgcccggaat gccaacctgg
    18721 acgacatcaa cgtggatgcg atcaatgggc tggccagcca gctgcgcgcc tacgctgaaa
    18781 tcgccgaata tcttccggag gtccggccca acctgcggga actcgcccgc gtcaccaggc
    18841 gagtgacccg aaaatggtta cgcaactacc cggagtcccc tgacgatgcc ggctacgccc
    18901 actcgaccgc cggcgtcctt gacgcctacc ttgcggccag ccacctgtgt ggggccaccg
    18961 tggacacggg tctggtcgag cagcaggttc aggctatcct tgcggccatt catgccaccg
    19021 ggaacgtttc ccagggttgg tgccatggta tggccgggtt cgggttcctg gccgcacact
    19081 tgtgtgatca cattgacacc cgggcggctg gcgagtcgct gctgagcgcc attcggcctg
    19141 gactactggc accagtcgac cacctggggc tgtcggtgtg ccatggggtt gccggcctcg
    19201 ccgaatcgct gatgagcctg tacacggcga ccggcgatga ggaaatcttg gaccgagccc
    19261 gatatctcat cgacgaggca attcccgccg acctggtggg ggacgggctg accaaagaaa
    19321 actattccgt cagcctcatg tgtggggtag ccggggtagg ccagctgctc ctgtccgccc
    19381 cgatcgtggc tgccccctgg caccccgtcg aacgaatgaa tgttctatgg cagaagaccg
    19441 cgtgatttcc gcaagtgtta ccatcgctct gggcggccat gggtgcgaca ccaaccgcac
    19501 ggttaaccgt gcctggtgtg gcatccccgg ttgccccgat gattcatggg tgtgaagagc
    19561 tcatgacaca tctgaatgaa tgactatgac gccactggtt ccccattccg gtggcgtcat
    19621 acctttgcgt ggccggccac cgcttgggcg tcgataagcg aaatgctagc ggtaaggttg
    19681 ggcgaatgta tattcgaaaa cttcggaata attgttcgct cacggcgaac caatggtggt
    19741 gaatggcgcg gaatgcgcta aactttagtc tgttagactc aactatgata ataactggca
    19801 ataatactgg aggaaaactt ggccgccaag aatgaatggg tagacaaaga ttactatgct
    19861 gaccttggtg ttacatccag cgcttcggat gcagacatta agaaggccta tcggaaactc
    19921 gcgcgcgaaa accacccgga ttcccacccg ggcgacgcga tccgggagga gaaatttaaa
    19981 aaggtcgctg aagcctatga cgtcgtgggc gatccgaccc gtcggaaaga atacgacgag
    20041 tttaaggaga tgctgcgtgt cggcggtggg tttcgcggcg gcggccaatc ctttcaagac
    20101 ttctcggata tttttggagg aggtcgttct accggcggtt ttagtgacat cttcggcggt
    20161 tcttggggtg ctactcgccg atcggctcgg ccgacgcggg ggtccgacgt ggagacggaa
    20221 attacgctag atttccgcga ggcagccaaa ggcaccacac taccagtcca actcaccggc
    20281 gacgccccct gcgccgcctg ccacggctcc gggtcccgca ccggtgccac cagcgcctgc
    20341 aaaaattgca acggcaccgg atacgtcacc gaaaaccggg gcgccttcgc gttctcggca
    20401 ccctgcccag actgcgatgg taccggcaaa gtcattaccg acccctgtcc ggattgccgc
    20461 ggcactggca cggtacgacg ctctcgatcc atcaccgtgc gcatccctgc cggcgtggtt
    20521 gatgggcaga aagtgcggct cgccggccaa ggcgaagctg gcccccacgg cacgcccgcc
    20581 ggcgatctat tcgtcacggt tcacgtccga cccgacaaag tattcacccg ggacggtgac
    20641 aacctggagg tagaggtgcc ggtctcgttc ggcgaactag cgctcggcgg caccgtgagc
    20701 gtgcccaccc tggaaaagcc ggtgcgggta cgcatccctg ccggcactcc tgacggccgg
    20761 gtgctgcggg ttcggggtcg gggcgtcccc aaacgcgacg gcagcttcgg cgacctctac
    20821 gtcaaggtga agatacgggt gcccaaggac ctgaccgatg atgcgaaaga tgcacttcgc
    20881 aactacatgg aggcggagaa acacatgggc ttcgaccccc gtgccacctg ggccggaaat
    20941 gagtcatgac catgaaagac ccatcgaact agtaaacatg tgagggagaa caaatcgaca
    21001 atgtccaaaa acaaaaacca agagtctatg ggcgaggttt ttgtgatctc ggttgcggct
    21061 gagttagctg gcatgcacgc ccagactctc agaacatacg atcgaatggg gttggtgacc
    21121 ccccaacgaa ccagcggggg tggccgccgc tactcccgtg aggatgttga gctgctccgc
    21181 accgtgcagc ggctcagtca ggaagacggc gtcaacctcg ccggcattaa ggccatcatc
    21241 caactcaaga aagaaaacga agaactccgc accaaactgc aggaggcccg cgccgaaaac
    21301 gaggtactca aacacaaccg gcatcgcggc gaaatcgtgc acgttccccg ctccaccgcg
    21361 gtagtgatgt gggagtctcg gcgagggccg aggcgtaaaa agcaaagcta gcacccataa
    21421 tctgccgcgg ttcgctcctg cggagccttc cgcacccagt ggccaatcac cccgggaacg
    21481 gtggcaggcc gcgggcccaa tagtccctgc tgattctggg tttgctccac cctccgcaac
    21541 acccctttga cggtggtgcc gcaggtggcc ttacgacgct tacccccgct gcgggagccc
    21601 cggccacccg gtgggatacc acccatcatg gcgccaccac cggcaacgcc accgcgacca
    21661 gtggtggccg cacccgtgcc gcccgtgccc gtgccaccca tgcgaccgca cgattctcga
    21721 aagtttgagc taactccccg agagccacta ccaccgctgc cagatgcccc aatacctgcg
    21781 ccgcgcggcg cagcaagcct tggtgcgccg gggaatccgc ccagtccgcc gatgctcccg
    21841 accccgccat gaccggtggg catcggccga ccactcacac cacctatccc cggagccgcg
    21901 ggggcctgcc caccaccaag agggtttgtg gagtgggcgg ccccagcacc tgtgatttcc
    21961 gcgggcaggg cataggcggc gcgttcggtg gctatttgac tagcgtttgt ggttccctgg
    22021 ccaccatagt ggccgggtgc cgggtggtaa tggggcgata tcccgccgcc accgggggcg
    22081 gcgggcatgt tcgctggccc catctgtccc ggttgtccca attgtccttg gtggggcgtg
    22141 gttgggggtg aaccgtatgc gtgtggcgtg cgctggcccg cgggattggg gtggtattgc
    22201 tggtgcactt gctctatccc ggaggccatg ctgtggcgta gttgctgcac cgtggggaag
    22261 tcctgcccca cctgctcggt catgccggcg accccaccac cgccgccacc gccggggagc
    22321 ggctgggtga gatttcgggt tgccggtatg gccgcctgga tggccgggcc gtacacgctg
    22381 tagaagtggg taagggcgag tttttcggca gcggttttct ccaccgggtc ctggatgata
    22441 tcggtagcgg ttttcatggc gaccaagctg ggggtgaaag cggcgggaat ggtggccagg
    22501 taggtgacgg ttgccgccat gtgggcggcg tttgccgaga attgggtggc cacctgggcc
    22561 atgtcggtga tgacccggca ggctgcgtcc acggcggtgc c
//
