LOCUS       NZ_GG770539            10399 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. SPB074 supercont3.1, whole genome shotgun sequence.
ACCESSION   NZ_GG770539
VERSION     NZ_GG770539.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. SPB074
  ORGANISM  Streptomyces sp. SPB074
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     The genome sequence of Streptomyces sp. strain SPB74
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   3  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   4  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Ward,D., Young,S., Jaffe,D., Gnerre,S., Berlin,A.,
            Heiman,D., Hepburn,T., Sykes,S., Alvarado,L., Kodira,C.D.,
            Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S.,
            Walsh,C.T., Lander,E., Galagan,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (25-FEB-2008) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Arachne v. April 2007
            Genome Coverage                   :: 12x
            Sequencing Technology             :: ABI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 01:42:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,117
            CDSs (total)                      :: 6,045
            Genes (coding)                    :: 5,425
            CDSs (with protein)               :: 5,425
            Genes (RNA)                       :: 72
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 261 of 620
            Pseudo Genes (incomplete)         :: 378 of 620
            Pseudo Genes (internal stop)      :: 38 of 620
            Pseudo Genes (multiple problems)  :: 54 of 620
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5637843
            Orig. end                         :: 5648242
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG770539.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated scaffolds were added in May 2010.
FEATURES             Location/Qualifiers
     region          1..10399
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="16"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10399
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5399](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5399)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    complement(314..329)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            530..2233
                     /locus_tag="SSBG_RS23875"
                     /old_locus_tag="SSBG_01788"
     CDS             530..2233
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012961.4"
                     /locus_tag="SSBG_RS23875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01788"
                     /product="glycoside hydrolase family 9 protein"
                     /protein_id="WP_008748637.1"
                     /transl_table=11
                     /translation="MTTTILTNHVGYQTAGSKKAVLLLPPGEPPATGADTALLHGPHGT
                     TTLSASEETAVDHWSAGTFRVVDFSAHTTEGTHHIEWAGTRSQPFTIGERVLQQATLSD
                     VLYYFRSVRSGGAIDRKDRAARFYEDTSGRTVDARGGWLDASGDYSKFLSHLNYTRMMN
                     PQQLPLCAWAFMEARDALAVHRPALVPVLGDRLRDEALFGADFLVRFQDPEGYFYTAIF
                     DALTKDLDERVINAPLADSVRTTRWQAAYRQGGGLAIAALARASALNDHGDFPSAAYLE
                     AARRGFDHLEAHNKKYLYDGEESVIDDYCALLAASELLAVTPGDPVLAEAAERRAASLM
                     DRHRADDGRGFGWLLGDVEGRPYFHAAESGLPALSLLRFAEVHPAAPLAERARATALAL
                     LGDAAALSDEVANPFGCVRQYVQPTEGPARTSFFYPHENETGYWWQGENANICSVAYAA
                     EKGAALDGCPPELRARLRRLAEDQLHWVLGLNPFDSCMIKGVGRNNIEYRPDYPNVPGG
                     ILNGITGGWDDERDIAFMPEEHRATGNGWRWTEQWIPHSAWFLLAMSAAR"
     gene            complement(2472..2684)
                     /locus_tag="SSBG_RS33365"
                     /old_locus_tag="SSBG_01787"
     CDS             complement(2472..2684)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009064052.1"
                     /locus_tag="SSBG_RS33365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01787"
                     /product="hypothetical protein"
                     /protein_id="WP_158677806.1"
                     /transl_table=11
                     /translation="MSRQGWSDAYGSGSTGRRLPVRCVKCADTHVILTKTGAPGNAPPR
                     WRYTCLDCRVAWWVDEHGGALDDYA"
     gene            2791..3018
                     /locus_tag="SSBG_RS23880"
                     /old_locus_tag="SSBG_01786"
     CDS             2791..3018
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007828628.1"
                     /locus_tag="SSBG_RS23880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01786"
                     /product="hypothetical protein"
                     /protein_id="WP_037870499.1"
                     /transl_table=11
                     /translation="MEHHMRAEYAEGDTPGDPRAPVRRWHMVRGAEEPRALCGVLLDPA
                     AVTQPADAWGTAAARPFCTRCGARYLREVP"
     misc_feature    3032..3043
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            3154..3885
                     /locus_tag="SSBG_RS23885"
                     /old_locus_tag="SSBG_01785"
     CDS             3154..3885
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009064048.1"
                     /locus_tag="SSBG_RS23885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01785"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_008748640.1"
                     /transl_table=11
                     /translation="MRVEIWTDIACPWCYVGKARFERALDGFAHRAEVEVVHRSFELDP
                     SFPKGQVVQVLPMIAKKYGVSEEQARQGEARLKENAEGEGLAYRTEGRDHGNTFDMHRL
                     LHLAKDRGRQDALIDGLYRGNFAEERTVFEDHERLVGIAVAAGLDEAETRAVLADETAY
                     AAEVRADEREAAELGANGVPFFVLDRRYGVSGAQPVEVFAQALQQAWDARPRLTPVAGV
                     AGAEEAGVCGPDGCAVPQPGA"
     gap             3906..4005
                     /estimated_length=unknown
     gene            complement(4096..4995)
                     /gene="thpD"
                     /locus_tag="SSBG_RS23890"
                     /old_locus_tag="SSBG_06289"
     CDS             complement(4096..4995)
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976953.1"
                     /locus_tag="SSBG_RS23890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06289"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_008748641.1"
                     /sec_met_domain="PhyH (E-value: 1.1e-37, bitscore: 128.7,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTHEKITDLYPTRGRTEVSTPRQDPVVWSAPGTAGPISAGELA
                     SFEENGFHAIPELLTPDEVAVYRAELDRLVADPAIRADERSIVEPRSQEIRSVFEIHKI
                     SEVFAKLVRDERLLDRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGMP
                     NMRAVSVSIALTENYDTNGGLMIMPGSHQTFLGCAGETPKDNYKKSLQMQDAGTPSDEA
                     LTEMAGKWGIKLFTGKAGSATWFDCNAMHGSGDNITPFPRSNVFLVFNSVENAAVEPFA
                     APIRRPEFIGARDFTPIR"
     gene            complement(5001..5399)
                     /locus_tag="SSBG_RS23895"
                     /old_locus_tag="SSBG_06290"
     CDS             complement(5001..5399)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="SSBG_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06290"
                     /product="ectoine synthase"
                     /protein_id="WP_008748642.1"
                     /sec_met_domain="ectoine_synt (E-value: 7e-53, bitscore:
                     176.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIRSFKDIEGTDRHVVAESGTWESKRIVLAKEKVGFSLHETIMY
                     AGTETTMHYANHIEAVLCVEGEAELTDETTGEKHWITPGTMYLLDNHDLHTMRPKTDFR
                     CVCVFNPPVTGREEHDENGVYPLLTEEG"
     gene            complement(5502..6770)
                     /gene="ectB"
                     /locus_tag="SSBG_RS23900"
                     /old_locus_tag="SSBG_06291"
     CDS             complement(5502..6770)
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-365). E-value: 4e-73.
                     Score: 238.3. Matches aSDomain:
                     nrpspksdomains_SSBG_RS23900_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="SSBG_RS23900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06291"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_008748643.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.7e-76, bitscore:
                     255.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIAPPDLSVFETLESEVRSYCRSWPAVFDRAQGSRLYDEDGHAY
                     LDFFAGAGALNYGHNNPVLKRALIDYIERDGITHGLDMGTTAKRAFLETFQNVILRPRD
                     LPYKVMFPGPTGTNAVEAALKLARKVKGRESIVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYLDGQTPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARP
                     EWLRALAELCKRQDMLLIVDDIQMGCGRTGGFFSFEGAGITPDIVTLSKSIGGYGLPMS
                     LCLFRPELDVWEPGEHNGTFRGNNPAFVTAAAALEAYWADGQMEKQTHARGEQVEAALR
                     AICLEHPRLGASYRGRGLVWGMEFTDAEQAAKVCRRAFEHGLLLETSGPRSEVVKLLPA
                     LTTTPEDLDEGLRILARAVRETA"
     aSDomain        complement(5676..6686)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS23900_Aminotran_3.1"
                     /evalue="4.00E-73"
                     /label="SSBG_RS23900_Aminotran_3.1"
                     /locus_tag="SSBG_RS23900"
                     /protein_end="365"
                     /protein_start="28"
                     /score="238.3"
                     /tool="antismash"
                     /translation="FDRAQGSRLYDEDGHAYLDFFAGAGALNYGHNNPVLKRALIDYIE
                     RDGITHGLDMGTTAKRAFLETFQNVILRPRDLPYKVMFPGPTGTNAVEAALKLARKVKG
                     RESIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYLDGQTPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARPEWLRALAELCKRQDMLLIVDDIQMGCGR
                     TGGFFSFEGAGITPDIVTLSKSIGGYGLPMSLCLFRPELDVWEPGEHNGTFRGNNPAFV
                     TAAAALEAYWADGQMEKQTHARGEQVEAALRAICLEHPRLGASYRGRGLVWGMEFT"
     gene            complement(6923..7504)
                     /gene="ectA"
                     /locus_tag="SSBG_RS23905"
                     /old_locus_tag="SSBG_06292"
     CDS             complement(6923..7504)
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009064039.1"
                     /locus_tag="SSBG_RS23905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06292"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_008748644.1"
                     /transl_table=11
                     /translation="MTAAQADLTAPRAAFREMPEGLRLDGPRVQDGAALWRLARDSGKL
                     DLNSSYSYLLWCRDFAATSVVARDAAGDPAGFVTGYIRPERPDVLVVWQVAVAAAQQGR
                     GLAAALLDGLAARVAARTALRGLETTITPGNVPSERLFTSFAARHGAGLEREVLFDAAL
                     FPADDEAGHEPEVLYRIGPLALAADRAEAA"
     misc_feature    7560..7571
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.9"
                     /tool="antismash"
     misc_feature    complement(7661..7676)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    7671..7686
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(7671..7688)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.47"
                     /tool="antismash"
     misc_feature    complement(7682..7699)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.07"
                     /tool="antismash"
     misc_feature    complement(7699..7716)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(7956..>8252)
                     /locus_tag="SSBG_RS35075"
                     /old_locus_tag="SSBG_06293"
                     /pseudo=""
     CDS             complement(7956..>8252)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007828644.1"
                     /locus_tag="SSBG_RS35075"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06293"
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="AAPVATTVRVPTTGTGPDAATLVAKALAAHPSLPLAAGGGALAAE
                     MIRVNHYGPLAAENVVRDCLRALTAAWGEATGERTDTRAADRAVAETWAAGRD"
     gap             8253..8352
                     /estimated_length=unknown
     gene            complement(<8353..9089)
                     /locus_tag="SSBG_RS35080"
                     /old_locus_tag="SSBG_06294"
     CDS             complement(<8353..9089)
                     /NRPS_PKS="Domain: Aminotran_5 (80-211). E-value: 4.2e-25.
                     Score: 80.3. Matches aSDomain:
                     nrpspksdomains_SSBG_RS35080_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007828644.1"
                     /locus_tag="SSBG_RS35080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06294"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_037870505.1"
                     /sec_met_domain="Aminotran_5 (E-value: 9.5e-21, bitscore:
                     72.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPLLDLTPLTAHHFATVERKVAALLGLDAPGSGGHELVVTQGE
                     ALLPLEGCIRGAAGPGTVALNIVTGPYGQTFGNWLRDCGATVHDLAVPFDSAVSAAQVR
                     EALAAHPETDFVSLVHAEAATGNTNPVAEIGAVVREHGALLMLDAVASVGAEPLLPAEW
                     GVDLCVIGAQKALGGPAGVSVAALSPRAWERLEANPAGPRGSYLSLLDWKHRWIDAGRK
                     ALPHAPAQLEMLALEACLERFAA"
     aSDomain        complement(8457..8849)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS35080_Aminotran_5.1"
                     /evalue="4.20E-25"
                     /label="SSBG_RS35080_Aminotran_5.1"
                     /locus_tag="SSBG_RS35080"
                     /protein_end="211"
                     /protein_start="80"
                     /score="80.3"
                     /tool="antismash"
                     /translation="RDCGATVHDLAVPFDSAVSAAQVREALAAHPETDFVSLVHAEAAT
                     GNTNPVAEIGAVVREHGALLMLDAVASVGAEPLLPAEWGVDLCVIGAQKALGGPAGVSV
                     AALSPRAWERLEANPAGPRGSYLSLLD"
     misc_feature    complement(9217..9226)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            9240..10343
                     /locus_tag="SSBG_RS23915"
                     /old_locus_tag="SSBG_06295"
     CDS             9240..10343
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007828647.1"
                     /locus_tag="SSBG_RS23915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_06295"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_086023077.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 6e-16, bitscore:
                     57.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDVSGTVPVLRVKGAVLVGPEDVRDEVWVVGGRITFTPPAGARD
                     VRTVAGWALPGLVDAHCHVGLDAHGAVPAEEAEKQALTERDAGALLLRDAGSPSDTRWT
                     DAREDLPRIIRAGRHIARTRRYIRNFAHEIEPEDLVAYVAREARRGDGWVKLVGDWIDR
                     EAGDLTACWPRGAVEAAIAEAHRLGARVTAHCFAEDSLADLVEAGIDCVEHATGLTEET
                     IPLFAERGVAIVPTLVNIATFPRLADGGEAKFPRWSAHMRRLHARRYETVRAAFDAGVP
                     VFTGTDAGGSLPHGLIGAEVAELVRAGLPPLAALSAAVWDARAWLGRPGIEEGAPADLV
                     VYESDPRADVRVLTAPRRVVMSGRVVA"
ORIGIN
        1 tgccggaggc ccgtatgccg ggcagcgctt tggtgacggc caatgcgcac ctctctcgct
       61 cggaactgcg caagtacctg aagaacgccc ggaacgtacc accgagacca gagcaagaca
      121 acgggtctga ccggatcggg atgtgaacgg cccgcgctct tgcggtaaca gggcggcccg
      181 cttgcgggag cttgcccgta ttcgtcctgg gtggcgcggt gttcgcggcg ccgtacgggg
      241 aaatttcgag tgcgttaggg atggacagga gccggtcgga tggcgttctc tggccatgtc
      301 cgcgatgccg tcgcagacca aatggtctca gtggtcatgt cggcgtccgg tcgccggagt
      361 ccccgtttcc cgcgagcttc cgcgcacccg ggcccccgca caccgggggc cgcgcgcggc
      421 ggagttcgcg caggccgggg ccccgcgccg ttcgcgtgta ccggggcccc gcgccccggt
      481 tctccggcgt cccgcagtcc ccgcgcaccg aaggagtggc acgtcccgca tgacgacgac
      541 gatcctcacc aaccacgtcg gctaccagac cgcgggcagc aagaaggccg tgctgctgct
      601 gccccccggt gagcccccgg ccaccggcgc ggacaccgcc ctcctgcacg gcccgcacgg
      661 caccacgacg ctctccgcga gcgaggagac cgccgtcgac cactggtccg ccggcacctt
      721 ccgcgtggtc gacttctccg cccacaccac cgagggcacc caccacatcg agtgggccgg
      781 cacccgctcg cagcccttca cgatcgggga acgcgtcctc cagcaggcca ccctctccga
      841 cgtcctctac tacttccgct cggtgcgctc cggcggcgcc atcgaccgca aggaccgcgc
      901 ggcgcgcttc tacgaggaca cctcgggccg caccgtggac gcgcgcggcg gctggctcga
      961 cgcctcgggc gactacagca agttcctcag ccacctcaac tacacgcgca tgatgaaccc
     1021 gcagcaactc ccgctgtgcg cctgggcgtt catggaagcg agggacgcgc tcgccgtgca
     1081 caggcccgcg ctcgtgcccg tgctcggcga ccgcctgcgc gacgaggcgc tcttcggcgc
     1141 cgacttcctc gtccgcttcc aggaccccga gggctacttc tacaccgcga tcttcgacgc
     1201 cctcaccaag gacctggacg agcgcgtcat caacgccccc ctcgccgact ccgtgcgcac
     1261 cacccgctgg caggccgcct accgccaggg cggcggcctc gcgatcgccg cgctcgcccg
     1321 cgcgagcgcc ctgaacgacc acggggactt cccctccgcg gcctacctgg aggcggcccg
     1381 gcgcggcttc gaccacctgg aggcgcacaa caagaagtac ctgtacgacg gcgaggaatc
     1441 cgtcatcgac gactactgcg cgctcctcgc ggcgagcgaa ctcctcgcgg tcacacccgg
     1501 cgaccccgtc ctcgccgagg ccgccgaacg ccgcgccgcc tcgctcatgg accggcaccg
     1561 cgccgacgac gggcgcggct tcgggtggct cctcggcgac gtcgagggcc gcccctactt
     1621 ccacgccgcc gagtccgggc tcccggcgct ctccctgctc cgcttcgcgg aggtccaccc
     1681 ggccgcgccg ctcgccgagc gcgcccgcgc caccgccctc gccctgctcg gggacgccgc
     1741 cgcgctcagc gacgaggtcg cgaacccctt cggctgcgtc cgccagtacg tccagcccac
     1801 cgagggcccc gcgcgcacga gcttcttcta cccgcacgag aacgagacgg gctactggtg
     1861 gcagggcgag aacgccaaca tctgctccgt cgcctacgcc gccgagaagg gcgccgccct
     1921 ggacggctgc ccgcccgagc tgcgcgcccg cctgcgccgc ctcgccgagg accagctcca
     1981 ctgggtgctc ggcctcaacc ccttcgactc ctgcatgatc aagggcgtcg gccgcaacaa
     2041 catcgagtac cggcccgact acccgaacgt ccccggcggc atcctcaacg gcatcacggg
     2101 cggctgggac gacgagcgcg acatcgcctt catgccggag gagcaccgcg ccaccggcaa
     2161 cggctggcgc tggaccgagc agtggattcc gcactcggcg tggttcctgc tggcgatgtc
     2221 ggcggcgcgc tgaaccggag gcacgagaaa cggccccggg cgaccggtac gtgggcggcg
     2281 cggcccccgc gcacacgacc gccgcgacca ccgggcccgc ccgcgtcccg cgtcgagggg
     2341 gggtggacgt cccgggccgt gaggtcaccg gatgcgccgt cgcgcccggc cccgtgcgca
     2401 cggccggcgg gcccgggctc gccgggcggc acggccgcgg cgtggtgcgc gcggccgaga
     2461 cgctgggtgg ctcacgcgta gtcgtcgagc gccccgccgt gctcgtccac ccaccaggcg
     2521 acgcggcagt ccaggcaggt gtaccgccag cgcgggggcg cgttgccggg ggcgccggtc
     2581 ttggtgagga tgacgtgggt gtcggcgcac ttcacgcagc gcaccgggag acgacgcccg
     2641 gtgctcccgg agccgtacgc gtcggaccac ccctgtcggc tcatgtcggc aattgtgcca
     2701 gcgacctgac gccgcctcgc ccgctccggc gcgcgggccg ggccgcgccg tgctgccatg
     2761 ggaccacacc ccacaggaga gggagcggcc atggagcacc acatgcgcgc cgagtacgcc
     2821 gagggcgaca cgcccggcga tccccgggcc ccggtccgca ggtggcacat ggtgcgcggc
     2881 gccgaggaac cccgtgccct gtgcggcgtg ctcctcgacc cggccgcggt cacccaaccc
     2941 gccgacgcct ggggcaccgc cgccgcgcgc cccttctgca cgaggtgcgg cgcgcgctac
     3001 ctgcgggaag tgccgtaggg cggacggccc ggggaatgaa cgcgggcccg gtccgcgttt
     3061 gcccgagcga cgtcctggac gtccccgagt acgacccgag ccgaagaggg cggtagaccg
     3121 atggcgacac ccctggcccc gaccccgtcc cccctgcgcg tggagatctg gacggacatc
     3181 gcctgtccgt ggtgctacgt ggggaaggcc cgcttcgagc gggcgctcga cgggttcgcg
     3241 caccgggcgg aggtcgaggt cgtgcaccgc tccttcgagc tggacccctc cttcccgaag
     3301 ggccaggtcg tccaggtgct cccgatgatc gccaagaagt acggggtcag tgaggagcag
     3361 gcgcggcagg gcgaggcgcg gctcaaggag aacgccgagg gcgaggggct cgcgtaccgc
     3421 accgagggcc gcgaccacgg caacaccttc gacatgcacc gcctcctcca cctcgcgaag
     3481 gaccgcggcc gccaggacgc cctgatcgac ggtctctacc ggggcaactt cgccgaggag
     3541 cgcaccgtct tcgaggacca cgagcgcctg gtcgggatag ccgtcgccgc cgggctggac
     3601 gaggccgaga cccgcgccgt cctcgccgac gagacggcgt acgccgccga ggtgcgcgcc
     3661 gacgagcgcg aggccgccga gctgggagcg aacggggtgc ccttcttcgt cctcgaccgc
     3721 cgctacggcg tctccggcgc ccagcccgtc gaggtcttcg cgcaggccct ccagcaggcg
     3781 tgggacgccc ggccgcggct gactcccgtc gccggggtgg ccggcgccga ggaggccggg
     3841 gtgtgcggcc cggacgggtg cgccgtcccc cagccgggcg cctgagcccc gccgggcacg
     3901 gcgaannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnccctt cgccggtcca
     4021 cacgggcctc gcccgtccac acgggtctcc gctcccgcac aaggcctccg cccgtacgcg
     4081 gtcgcggcct ccgcctcagc ggatcggcgt gaagtcccgc gcgccgatga actccgggcg
     4141 ccggatcggc gcggcgaagg gctcgacggc cgcgttctcg acgctgttga agacgaggaa
     4201 cacgttgctg cgcgggaacg gggtgatgtt gtcccccgag ccgtgcatcg cgttgcagtc
     4261 gaaccaggtc gccgagcccg ccttgccggt gaagagcttg atgccccact tcccggccat
     4321 ctcggtgagc gcctcgtccg agggcgtgcc cgcgtcctgc atctggaggg acttcttgta
     4381 gttgtccttc ggcgtctcgc ccgcacagcc caggaaggtc tggtgcgagc cgggcatgat
     4441 catgagcccg ccgttggtgt cgtagttctc ggtgagcgcg atcgacacgg agacggcgcg
     4501 catgttcggc atcccgtcct cggcgtgcca cgtctcgaag tccgagtgcc agtagaagcc
     4561 ggaggcgccg aagccgggct tgacgttgat ccgcgactgg tggacgtaga cgtccgagcc
     4621 gaggatctgc cgggcgcggt ccagcagccg ctcgtcgcgc acgagcttcg cgaagacctc
     4681 actgatcttg tggatctcga agaccgagcg gatctcctgc gaccgcggct ccacgatgga
     4741 gcgctcgtcc gcgcggatcg cgggatcggc gacgagccgg tccagctcgg cgcggtagac
     4801 cgcgacctcg tccggggtga gcagctcggg aatcgcgtgg aagccgttct cctcgaagga
     4861 ggcgagctca ccggcgctga tcggcccggc ggtaccgggc gcggaccaca ccaccgggtc
     4921 ctggcgcggc gtggagacct cggtccggcc gcgcgtcggg tagaggtccg tgatcttctc
     4981 gtgggtgacg gtcatctcgc tcagccctcc tctgtcagca gcgggtagac accgttctcg
     5041 tcgtgctcct cgcgcccggt gacgggcggg ttgaagacgc agacgcaacg gaagtcggtc
     5101 ttgggccgca tcgtgtgcag gtcgtggttg tcgagcaggt acatcgtccc gggcgtgatc
     5161 cagtgcttct cgcccgtcgt ctcgtcggtc agctccgcct cgccctcgac acagagcacc
     5221 gcctcgatgt ggttggcgta gtgcatcgtc gtctcggtgc cggcgtacat gatcgtctcg
     5281 tgcagcgaga agccgacctt ctccttggcc agcacgatgc gcttgctctc ccaggtgccc
     5341 gactcggcga cgacgtgccg gtcggtgccc tcgatgtcct tgaacgagcg aatgagcacg
     5401 gtgttcctgt gcctctcttc cgtgattccg tggtgcggtg ttcttgcccg ggcacggggc
     5461 ggtgctcgcg tcgcttcggc gtcctcgccc cgaaccggtt ctcaggcggt ctcgcggacc
     5521 gcgcgggcga ggatgcgcag cccctcgtcc aggtcctccg gcgtcgtggt gagcgcgggc
     5581 agcagcttca cgacctcgct gcgcggcccg gaggtctcca ggagcagccc gtgctcgaag
     5641 gcgcggcggc acaccttcgc cgcctgctcg gcgtcggtga actccatgcc ccacacgagg
     5701 ccgcggcccc ggtaggaggc accgaggcgg gggtgctcca ggcagatggc gcgcagcgcc
     5761 gcctcgacct gctcgccgcg cgcgtgggtc tgcttctcca tctggccgtc cgcccagtac
     5821 gcctccaggg cggcggcggc cgtgacgaag gccgggttgt tgccgcggaa ggtgccgttg
     5881 tgctcacccg gctcccacac gtccagctcg gggcggaaga ggcacagcga catgggcagc
     5941 ccgtagccgc cgatggactt cgacagcgtc acgatgtccg gcgtgatgcc ggccccctcg
     6001 aaggagaaga agccgccggt gcgcccgcag cccatctgga tgtcgtccac gatgagcagc
     6061 atgtcctgcc gcttgcacag ctcggcgagc gcgcgcagcc actccgggcg cgccacgttg
     6121 atgccgccct cgccctgcac ggtctccacg atcacggcgg cgggcttgtt gagcccggag
     6181 ccctggtcct ccaggagccg ctcgaaccag aggaagtcgg gggtctgccc gtcgaggtag
     6241 ttgtcgaagg gcatcggcgt gccgtgcacg agggggatgc ccgcgcccgc gcgcttgaag
     6301 gcgttgcccg tgacggcgag ggagccgagg gacatgccgt ggaaggcgtt ggtgaaggag
     6361 acgatcgact cgcggccctt gaccttgcgg gccagcttga gcgccgcctc caccgcgttg
     6421 gtccccgtcg ggccgggaaa catgaccttg tagggcaggt cgcgggggcg caggatcacg
     6481 ttctggaacg tttcgaggaa cgcgcgcttg gccgtggtcc ccatgtcgag gccgtgggtg
     6541 atgccgtcgc gctcgatgta gtcgatgagg gcgcgtttga ggaccgggtt gttgtggccg
     6601 tagttgaggg caccggcgcc ggcgaagaag tccaggtacg cgtggccgtc ctcgtcgtag
     6661 agacggctgc cctgggcgcg gtcgaacacg gcgggccagc ttcggcagta actgcgcacc
     6721 tccgactcca gggtctcgaa gacgctcagg tcgggcgggg cgatggtcac agctgtctcc
     6781 tgggggaaga gggtggagcg gagcagggag tgtggacttg cggtacggat gcgggaccgc
     6841 ggtgccggtg ggcggtacgg gcccgggggt gccgtccggt gcacgggccg gccccgggtg
     6901 ggcgccggcc cgaccgctcg gctcaggccg cttcggcgcg gtccgccgcg agggcgagcg
     6961 ggccgatgcg gtacagcact tcgggctcgt gtccggcctc gtcgtccgcc gggaacagcg
     7021 cggcgtcgaa gagcacctcg cgctccaggc ccgcgccgtg gcgcgcggcg aaggaggtga
     7081 agaggcgctc ggagggcacg ttgccggggg tgatggtggt ctccaggccg cgcagcgcgg
     7141 tgcgcgcggc gacgcgggcg gcgagtccgt cgagcagcgc ggcggccagg cccctgccct
     7201 gctgcgcggc ggccacggcg acctgccaga cgacgaggac gtcggggcgt tcgggccgga
     7261 tgtagccggt gacgaaaccg gccgggtccc cggcggcgtc ccgcgccacc acggaggtcg
     7321 cggcgaagtc gcgacaccac agcaggtaac tgtacgagga gttcaggtcg agctttccgg
     7381 agtcgcgggc gagacgccac agcgcggcgc cgtcctgcac gcgtgggccg tcaaggcgta
     7441 gtccctccgg catttcccgg aatgcggcac ggggtgcggt gaggtctgct tgtgcggcgg
     7501 tcatgggatt tgaacttacc cagcaggcgc agaaaattca tcgggtgcca gggttgggtg
     7561 aaaaggtgtt ctgtgttatc gcgcgtgcgg gtgctcgggc gcgaaacccc ccacgaaatg
     7621 cccaatatgt ggcgggcatt ggggatgaaa ggggcttctt tgtggactcg gtcacaaaga
     7681 agtaacaccc gtggaacctg tccgaattat gggagatgtg cgagggccaa aacttcttgt
     7741 ttagcccccg ggaaagcggg cagaagaata tgggaagctg tgctcagaaa tgcacgggga
     7801 attaatccgg agtttatatc gtgctgaata tgtgcgcggt atttccaggg aagccgcacc
     7861 acggcgcacg gcgtggcacc gggtgccgcg ccggcaccgg cgagggcgcg gggcgcgccg
     7921 tccggcggaa cgccccgcac cgtccccgcg cgggctcagt cccggccggc cgcccaggtc
     7981 tccgccaccg cgcggtcggc cgcgcgcgtg tcggtccgct cgcccgtcgc ctcgccccac
     8041 gccgccgtga gcgcccgcag gcagtcccgt acgacgttct cggccgcgag cgggccgtag
     8101 tggttgacgc ggatcatctc ggccgcgagc gcgccgccgc ccgccgcgag cggcagcgag
     8161 gggtgcgcgg cgagggcctt cgcgacgagc gtcgccgcgt ccgggcccgt ccccgtcgtg
     8221 ggcacccgca cggtcgtcgc gaccggcgcc gcnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8341 nnnnnnnnnn nntcggcggc gaagcgctcc aggcacgctt cgagcgccag catctccagc
     8401 tgcgcgggag cgtgcgggag cgccttgcgg cccgcgtcga tccaccggtg cttccagtcg
     8461 agcagggaga ggtacgagcc ccgcgggccc gccgggttcg cctccaggcg ctcccaggcg
     8521 cgcgggctca gcgccgccac cgagaccccg gccgggccgc cgagcgcctt ctgcgccccg
     8581 atcacgcaca ggtccacgcc ccactcggcg ggcagcagcg gctccgcgcc caccgaggcg
     8641 acggcgtcga gcatgagcag cgccccgtgt tcgcgcacca ccgcgccgat ctccgcgacc
     8701 gggttggtgt tgcccgtcgc ggcctccgcg tgcacgagcg agacgaagtc cgtctccggg
     8761 tgcgcggcca gcgcctcacg cacctgcgcc gcgctgaccg ccgagtcgaa gggcaccgcg
     8821 aggtcgtgca ccgtggcgcc gcagtcgcgc agccagttgc cgaaggtctg cccgtagggg
     8881 cccgtcacga tgttcagcgc gaccgttccc ggaccggcgg ccccccggat gcacccttcg
     8941 aggggcagca gcgcctcgcc ctgcgtcacg acgagctcgt gccccccgct gccgggcgcg
     9001 tcgagcccga gcagggcggc gaccttgcgt tcgacggtcg cgaagtggtg ggcggtcagg
     9061 ggagtgaggt caagcagggg gtgtgtcacg aggtggctct ttctgcgtgt gccgagtgcg
     9121 gcgtgcgcgc gtgtcgcctg cggcgacacg gggacggatg gccgtgcggg ccggttgtga
     9181 gggtactcag gggggtgcgg ggaagagggc ggggcgggcc gccttctagg gtgccggtca
     9241 tggacgacgt gagcggaacg gtgccggtgc tgcgggtgaa gggggccgtc ctcgtggggc
     9301 ccgaggacgt gcgcgacgag gtgtgggtgg tcggcgggcg gatcacgttc acgcccccgg
     9361 ccggggcgcg ggacgtccgc accgtggcgg gctgggcact gcccgggctc gtggacgcgc
     9421 actgccacgt cgggctcgac gcgcacggcg ccgtgcccgc cgaggaggcc gagaagcagg
     9481 cgctcaccga gcgggacgcg ggcgcgctcc tgctccgcga cgcgggctcg ccctccgaca
     9541 cgcgctggac ggacgcgcgc gaggacctgc cccgcatcat ccgcgccggg cgccacatcg
     9601 cccgcacccg ccgctacatc cgcaacttcg cccacgagat cgagccggag gacctcgtcg
     9661 cctacgtcgc ccgcgaggcg cggcgcggcg acggctgggt caagctcgtc ggtgactgga
     9721 tcgaccgcga ggcgggcgac ctgacggcgt gctggccgcg cggcgcggtc gaggcggcga
     9781 tcgccgaggc gcaccggctc ggcgcgcgcg tcaccgcgca ctgcttcgcc gaggactcgc
     9841 tcgccgacct ggtcgaggcg ggcatcgact gcgtcgagca cgcgacgggg ctcaccgagg
     9901 agaccatccc gctcttcgcg gagcgcggcg tcgcgatcgt cccgaccctc gtcaacatcg
     9961 cgacgttccc acgcctcgcg gacggcggcg aggcgaagtt cccacgctgg tcggcccaca
    10021 tgcgccgcct gcacgcccgc cgctacgaga cggtgcgggc cgccttcgac gcgggcgtcc
    10081 ccgtcttcac cggcaccgac gcgggcggca gcctcccgca cggcctcatc ggcgcggagg
    10141 tcgccgaact cgtccgcgcg ggcctcccgc cgctggccgc gctctccgcc gccgtctggg
    10201 acgcccgcgc ctggctcggc aggcccggca tcgaggaggg cgccccggcg gacctcgtgg
    10261 tgtacgagag cgacccgcgc gcggacgtac gggtcctgac ggcgccccgc cgcgtcgtga
    10321 tgtcggggcg ggtggtggcg taggcgcggc ggcgcagaca cgtgcggggc ggtggcgacg
    10381 cgggggtcgc gggacacgt
//
