LOCUS       NZ_GG770539            25287 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. SPB074 supercont3.1, whole genome shotgun sequence.
ACCESSION   NZ_GG770539
VERSION     NZ_GG770539.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. SPB074
  ORGANISM  Streptomyces sp. SPB074
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     The genome sequence of Streptomyces sp. strain SPB74
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   3  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   4  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Ward,D., Young,S., Jaffe,D., Gnerre,S., Berlin,A.,
            Heiman,D., Hepburn,T., Sykes,S., Alvarado,L., Kodira,C.D.,
            Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S.,
            Walsh,C.T., Lander,E., Galagan,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (25-FEB-2008) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Arachne v. April 2007
            Genome Coverage                   :: 12x
            Sequencing Technology             :: ABI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 01:42:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,117
            CDSs (total)                      :: 6,045
            Genes (coding)                    :: 5,425
            CDSs (with protein)               :: 5,425
            Genes (RNA)                       :: 72
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 261 of 620
            Pseudo Genes (incomplete)         :: 378 of 620
            Pseudo Genes (internal stop)      :: 38 of 620
            Pseudo Genes (multiple problems)  :: 54 of 620
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2962654
            Orig. end                         :: 2987941
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG770539.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated scaffolds were added in May 2010.
FEATURES             Location/Qualifiers
     region          1..25287
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="13"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25287
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25287
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15287](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15287)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(141..150)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            273..752
                     /locus_tag="SSBG_RS12135"
                     /old_locus_tag="SSBG_01058"
     CDS             273..752
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020463.4"
                     /locus_tag="SSBG_RS12135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01058"
                     /product="WbqC family protein"
                     /protein_id="WP_324603508.1"
                     /transl_table=11
                     /translation="MLRQNFGASPYWHSLTHVLDPVLDALGRIAVVAETSTRVLLDLFG
                     WRGRMLSSSLLAARPGRSSRLADLAAATGARAYLCGTGGMTYLDPAPFAARNIPVAAFR
                     PPTTGIWSTARRLSSLYALAALGPDTLAARLRSVADDNAALAAATAGYGPLARER"
     gene            complement(1092..2006)
                     /locus_tag="SSBG_RS12140"
                     /old_locus_tag="SSBG_01057"
     CDS             complement(1092..2006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008749689.1"
                     /locus_tag="SSBG_RS12140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01057"
                     /product="transposase family protein"
                     /protein_id="WP_008746426.1"
                     /transl_table=11
                     /translation="MVNRAVLAHRLFTGLSRRHLACLVEELAEPWQAGVEGRRHAVRGG
                     ARKRAEGAGARHQLVFVDRLVATLIHLRHDLPHSVLGLLSGVDRSTVTRAIGEVRTLLA
                     ERGCAVPDRPGLRLRTLADVFAYAQAEGVELCLDATEIRVRRPPAGRGGRRAFVSGKKK
                     QNTMKATVIAGWRGRTLWTDALRPGRMHDATAARDEGIAICFQHFPDVEVLLDDGYLGL
                     SRDHRGQAITPPRKPRPGALPDRVEQWGRDRHGHSSDRITVEHALADHKRWKQLTRWTH
                     RRDRLPDTYRAIAGLVSDRNTSI"
     misc_feature    complement(1467..1469)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(2000..2014)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            complement(2049..2447)
                     /locus_tag="SSBG_RS12145"
                     /old_locus_tag="SSBG_01056"
     CDS             complement(2049..2447)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023583.4"
                     /locus_tag="SSBG_RS12145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01056"
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="WP_008746427.1"
                     /transl_table=11
                     /translation="MITGELKSKIDRLWDAFWSGGISNPLEVIEQITYLMFIRRLDILE
                     QAKENKANRTGRPVENPIYADDTQILRWSVFINESPENMLTRVRDGVFPWLRTLGGEDS
                     TYAHHMKDARFTITTSNLLTNELVRDSG"
     gene            complement(2520..3389)
                     /locus_tag="SSBG_RS12150"
                     /old_locus_tag="SSBG_01055"
     CDS             complement(2520..3389)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070516.1"
                     /locus_tag="SSBG_RS12150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01055"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_008746428.1"
                     /transl_table=11
                     /translation="MVFRWDWLRPALAAPVVPTLGPVHPHALTVDLFEATLVAAASECH
                     FLPYDKDRRWGAEKQEAVLVNDVVHHPDHTLIPTLLTRGGRTVKVFAYGQRGDVLDQAA
                     ELAGKLAAVHGAATARVVRPLGPETPHPRGVRIQLQDFTARHYSPSVGPVRRLEDWPLP
                     VRRTFTTFAQTMAADGFAFLDRQMRAKGCGPVLVAVLEDRVVGAIGPMEICPDPTGMAQ
                     LMPQYFAVDPDARGHGLGRHLWRAAMHWGQTHGATYQLLQTEVGGASDHLCRNEGLTTL
                     GFLHARTV"
     gene            complement(3467..3634)
                     /locus_tag="SSBG_RS33665"
     CDS             complement(3467..3634)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009067805.1"
                     /locus_tag="SSBG_RS33665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_199781359.1"
                     /transl_table=11
                     /translation="MTPGPVPVQILTAPPSSARHAAPPVASAAVTLVADLDDVVESAEC
                     SCDAGDDNPF"
     gene            complement(3631..4761)
                     /locus_tag="SSBG_RS12155"
                     /old_locus_tag="SSBG_01053"
     CDS             complement(3631..4761)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009067806.1"
                     /locus_tag="SSBG_RS12155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01053"
                     /product="radical SAM protein"
                     /protein_id="WP_037869571.1"
                     /sec_met_domain="PF04055 (E-value: 1e-16, bitscore: 60.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.2e-06, bitscore: 23.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHQLIAAPFLDGHLLLRPGARSGARIPATHYEQLRAAAVNAQPLP
                     SWAVELAADAWGLDVAGAPTKHTVLIREPSAYGYCRASWEINLGCNFGCKHCYLGERPF
                     SGLTWENKVELLDIMREAGVIWLQITGGEPTMDPDFQNAYRYAWLSGMMLTISTNGSLL
                     SRPDLLQLFRECPPYRLVVSMYGASEESFDALTQRRGAWKAFRRGMHAARAAGLPLRIN
                     VVVTEDNAREADAMAALAREWGVEHHAYTNMTPTIYGGGEPLLAQSADHLRRRKPFAGC
                     NAGHTFFHADPHAKVSICKVGREEQIDLMAEGVEGLRRLGTIADRLMLRTGGCEGCALS
                     GTCRVCRPLAKHYQEAKAPLHSYCQHGDPQKETVPP"
     gene            complement(4784..5350)
                     /locus_tag="SSBG_RS12160"
     CDS             complement(4784..5350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010276672.1"
                     /locus_tag="SSBG_RS12160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_037869573.1"
                     /transl_table=11
                     /translation="MSIALIPPSPELRLHVSLAAWTWKGAGPDNREIARILITHTPAPT
                     NGGTAATTEDHMRRLSGCLGGLTGAREVIPRLGRRLRLVGDRALLHVPGASRRLPLPTR
                     RSWNELVARTSEAILVLGLDALPQSADAARLDTYLDAALTSDRLLFGRIQLSPSVPRAD
                     VCPTCGGSGTDPLSGCACPDCSLHC"
     gene            complement(5347..5748)
                     /locus_tag="SSBG_RS12165"
                     /old_locus_tag="SSBG_01052"
     CDS             complement(5347..5748)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010276675.1"
                     /locus_tag="SSBG_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01052"
                     /product="ATP-binding protein"
                     /protein_id="WP_008746430.1"
                     /transl_table=11
                     /translation="MTKTTQRFFESRPESVAEARTFTAEALTSWGLLERGDDVRLCVSE
                     LATNAVLHGAAPGRGFLVKIDADDEAVRLEVHDSRSRRPHPRRPDDTDTVGRGLILVTA
                     LADGWGVEDRTPLGKIVWSCFKAPGGTAA"
     gene            complement(5760..6191)
                     /locus_tag="SSBG_RS12170"
                     /old_locus_tag="SSBG_01051"
     CDS             complement(5760..6191)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010276678.1"
                     /locus_tag="SSBG_RS12170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01051"
                     /product="hypothetical protein"
                     /protein_id="WP_037869574.1"
                     /transl_table=11
                     /translation="MEPLTEHRLVSGPVVYGFLRLIRVPRARQNALAASLAEYCRAHEL
                     RLSGLFTDREATGAASAAFNGLLDALALPDVYGVVVPAMSHLGPKAVAVERGRQIECAG
                     ARLLLVRRARPTPSTVPRSGPVHRPHSGTTRVVDATSLS"
     gene            6345..7445
                     /locus_tag="SSBG_RS12175"
                     /old_locus_tag="SSBG_01050"
     CDS             6345..7445
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009067507.1"
                     /locus_tag="SSBG_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01050"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_037869575.1"
                     /transl_table=11
                     /translation="MATVHHWTGLEAKALRLALRLSVRSFAERLGLAVATVSKWESKLA
                     ATEPRPDTQAILDTALGRADAAVHLRFETLLSEMAGSVATAGRRVTPSGPRAWEYESWA
                     DDLDRVVVALSRQDFAFADSLLTRWLGRFTAHELDEKGLYLFGRSSTLLGDLKRDQGVV
                     LGPLSAQHSYNGARTVFTQLDIPRRVAQLDLSLAVVTEMSGKLEVAAHSYESLAVDDRL
                     SRRDRARARLWVGTALSKDGEHDYATRVMQAATREFEDLTEPEDWSVAHQKLALARRGV
                     GDLSQALHFIDIARSSGTTDSPMQRVRLDTAHGHILLSDAATRDDGVLVLDRAARVAAQ
                     YGLVHQLRSIEGIRAMSEGLTGPRQR"
     gene            7460..8128
                     /locus_tag="SSBG_RS12180"
                     /old_locus_tag="SSBG_05700"
     CDS             7460..8128
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009067508.1"
                     /locus_tag="SSBG_RS12180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_05700"
                     /product="YdcF family protein"
                     /protein_id="WP_008746433.1"
                     /transl_table=11
                     /translation="MRNDQQGITEDQWHQARLIWDYHQMQHELRPVDVAIGLGSHDLGV
                     ATRSAELYRAGLFETLVFTGGNSPTTAKVFPRGEAIHFREHAIDLGVPADAILLEPHAA
                     NTGENITLSREVLAASGIHPATVLLVSKPYMERRSFATARKLWPDVEFLCASERLEFDD
                     YLRSIGDEKLVLDMLAGDLQRVIEYPKLGFAIEQEVPEDVHAAYESLIRSGFTSRLIAS
                     "
     gene            complement(8242..9244)
                     /locus_tag="SSBG_RS31010"
                     /pseudo=""
     CDS             complement(8242..9244)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612357.1"
                     /locus_tag="SSBG_RS31010"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRMQLTDAEWDSSGRTCRSASTARTPSGCGSSSRA"
     misc_feature    complement(9295..9308)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            complement(9451..9957)
                     /locus_tag="SSBG_RS12195"
                     /old_locus_tag="SSBG_01046"
     CDS             complement(9451..9957)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327529.1"
                     /locus_tag="SSBG_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01046"
                     /product="topology modulation protein"
                     /protein_id="WP_037869576.1"
                     /transl_table=11
                     /translation="MKKVAIVGCAGSGKSHVARHLGRILNAPVTHLDAVFCDDEWNALP
                     MDEFTRVQSELVAEPRWVIDGNYNSTLQVRLEACDTVVLMDVSTVAALYGIFSRQVRHG
                     AGHKGNGVHNRIHWGVIKYVATYRRMMRPRVMAKINEFNSGAEVVLLANRRQTHRWLRR
                     VAGEQ"
     gene            complement(10001..11029)
                     /locus_tag="SSBG_RS12200"
                     /pseudo=""
     CDS             complement(10001..11029)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="SSBG_RS12200"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /pseudo=""
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.8e-16, bitscore:
                     56.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRMSADQLISTEPSPIHRAVTAALTSLLIPEVAAQHGMEPTTLS
                     DALAVYDQAGREALARHASTDDWWQVYLHFTDWTKADETFTVHVLPLLQEAETAGLIGG
                     WWYTRKHPCWRLRLRVRPGIGAKIGAAEGLDRLGLHRLVADGHLARWWPGIYEPETAAF
                     GGEASMTAAHALFITDSREAAQLR"
     gene            complement(11002..12228)
                     /locus_tag="SSBG_RS12205"
                     /old_locus_tag="SSBG_01043"
     CDS             complement(11002..12228)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490581.1"
                     /locus_tag="SSBG_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01043"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_008746440.1"
                     /sec_met_domain="LANC_like (E-value: 4e-34, bitscore:
                     116.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALAATTAILEQYTAHLAQPAPPPPDEPWAVQSLADGAAGISLL
                     HIETVSRHGGSWRPAHRWITAAAAGHISAADTAGLFLGAPALGFVLTTVPPSFQHLYEP
                     ARRTLHQHITDLTHRRVDAALTRIRKGDLPAFAEYDLFYGLTGIGAYLLRTDPEGLPLE
                     RVLKYLVALTRPLAPDGRGLPGWWVRHDPARGESPHFPGGHGNFGAAHGITGPLLLLAQ
                     AMRRGITVGGHREAIWSICEHLDTWCQLSPSGPWWPEHISRRDFDLGRPHHDAPARPSW
                     CYGTTGIARAGQLAGLALHAPDVQGFYEDALYRALTDPEQLAQVTDSGLCHGWAGIYQT
                     ATRAAADAVDPRLQALPRSLGDTLATSARPGLPEPGLINGDAGTALALTTHASQQAPNT
                     GWDACLLIN"
     gene            complement(12225..15287)
                     /locus_tag="SSBG_RS12210"
                     /old_locus_tag="SSBG_01042"
     CDS             complement(12225..15287)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380186.1"
                     /locus_tag="SSBG_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01042"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_008746441.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.9e-197,
                     bitscore: 655.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 6.9e-17,
                     bitscore: 60.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.3e-11, bitscore:
                     42.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASRAAAGYLWQGVAMLRATTSPGPADIPRTLDLDNVAVTRGWLN
                     RIWQREDFRSALELATPVLSDAIEAVVRGRQTEPRHVRRTALSTVSYLLRWQHRPTPLG
                     LFAGTAPVSVGPRASARWRDKHRATIRPDAEWVTDMVLRLQRTPALLERLPLVANNAAR
                     ARGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAALDAARTPIPYRGLHGHLRDLFPQ
                     ATPEKIDALLASLVEQRFLITSLWAPMTTVDAFQHLCRELDGLQADNIPEVRDLVHELY
                     ALRDELSAHQPTLSDTSVSTVATRMRALTPVTPTPLLIDTALDCETTLPQAVIAEAQAS
                     VSALYRTTPQPYGYQHWRDYHRRFRARYGVGALVPVMDLVADSGLGLPAGYVGSERGAA
                     LKVRTDRDELLLAMMQQVLLDGGRELRLTDDMVDALEKAAGKDERLFVPRVEVAFEVHS
                     SSTRALSSGAFDILLTAVPRPGSSMAGRFAHALPPEHQDALAATYHGAPNSLTAQLVFP
                     PRRHRNENVTRTLRLLPHVIELSGHQETDATTIPLADIAVTVDPRSFHLVQLSTGRRID
                     VRVLHALEGGTQTPPLARFLAEVANGRFAAYKPFDFGAGSRLPFLPRVRYRRTILTQAR
                     WLLMADDLPGRKASIQEWESAFAAWRDRLRAPEQVAMIEYDQRLPLDLSHPVHLRVLRA
                     HLDNTRRLELRELPDADAHGWIGRAHEIWLSLGRSEPAAEVPRPRTAPSAAPDRHLPGA
                     GDVLLAQLHAHPRRYDEILSRRLPSLLAAFGDAPPLWWFTRHREMARPDADQHLDLTLH
                     LPPDAYGAAAQHVRRWADSLHGTGLAAGLVLAPYQPQTGRFGHGTAMDAAHRVFAADSA
                     VALAQIQLTERTDALAPQALAAASALHLVTPLAPDTAAAEEWLVRNLPQGTGRLNRALR
                     AQVLELAAPNGDSVLAALPGGPAVVEAWRARAAAVDTYRTALTDHRDPLDVARSLLHQH
                     HVRALGVDPRAEETTIRLVRTAALQHRRAAR"
     aSDomain        complement(14544..14819)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SSBG_RS12210_Lanthipeptide_LanB_RRE.1
                     "
                     /evalue="3.30E-19"
                     /identifier="RREFam001.1"
                     /label="SSBG_RS12210"
                     /locus_tag="SSBG_RS12210"
                     /protein_end="248"
                     /protein_start="156"
                     /score="60.4"
                     /tool="antismash"
                     /translation="VANNAARARGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAALD
                     AARTPIPYRGLHGHLRDLFPQATPEKIDALLASLVEQRFLITSLWAP"
     misc_feature    complement(14826..14828)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14838..14840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15380..15580)
                     /locus_tag="SSBG_RS12215"
                     /old_locus_tag="SSBG_01041"
     CDS             complement(15380..15580)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380187.1"
                     /locus_tag="SSBG_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01041"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_008746442.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.8e-14, bitscore:
                     51.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSATLAPPPVVAPSADLDDDFAPLDVKVVIAEHSYGHLMCSTGD
                     GCGTTCATGASACGSFTEDPA"
     gene            complement(15635..16873)
                     /gene="fxlM"
                     /locus_tag="SSBG_RS12220"
                     /old_locus_tag="SSBG_01040"
     CDS             complement(15635..16873)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490583.1"
                     /locus_tag="SSBG_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01040"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_008746443.1"
                     /sec_met_domain="PCMT (E-value: 2.7e-36, bitscore: 123.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNTTVKPDEATRLRNKVVDELCADGNISSSEIEAVMRKVPRHEF
                     TPADTPLDKAYDTYAAVITKTDEHGVQISSVSAPQIQAMMLEQAQVKPGMRVLEIGSGG
                     LNAAYLAELVGEDGEVVTVDIDPEVTDRARRLLDDHGYGRVHVVTVDAAEPIPDLGEVD
                     VVMVTAGAWDISPAWTAQLKSGGRLVVPLRMRGLTRSVSFIQVEGEHGPYLASESAKIC
                     GFVPMQGSTAHREELLLVNGTPEIGLKFDDGLPADPHRLDNAVTFPRHELWTGVSVRIQ
                     ELIDTLQMAMAISLPGFCTMAVDENADTGVVDPVNKRFALAAVEDDTFAYLVTRRTEDN
                     KHLEYGVHALGPHAEQFADEIAGVLRDWEANRRGGPSPVIRVYPASTPDEQIPADRVID
                     KVHSRISLSWPSA"
     gene            complement(17028..17693)
                     /locus_tag="SSBG_RS12225"
                     /old_locus_tag="SSBG_01039"
     CDS             complement(17028..17693)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SSBG_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SSBG_01039"
                     /product="hypothetical protein"
                     /protein_id="WP_008746444.1"
                     /transl_table=11
                     /translation="MKRTSAAPRLVPYITQREGEYGGLESELTLSMNAFGAVRLAYQDE
                     TPADRGPRGELWARCSQSLNAAGKPTGRPQWRMVNPVRQREAMEQLRCQVSFCPAETDQ
                     GYIFLAGNSEGASHRAGEPVRTAQPPVCLKHLRPSIELCLHLRKGHIAFRARATSPWGV
                     IGTRYRLTATGLEPLLADDDDAPVAYGHPQSGWFLASQLIRELRNYEVVNLDDLVPAA"
     gene            complement(17690..17890)
                     /locus_tag="SSBG_RS12230"
                     /old_locus_tag="SSBG_01038"
     CDS             complement(17690..17890)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006350454.1"
                     /locus_tag="SSBG_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01038"
                     /product="DUF5999 family protein"
                     /protein_id="WP_008746445.1"
                     /transl_table=11
                     /translation="MCAHNPPCPTAEAPDREAARPLAHRPEQGWSLLCNGVLLFEDTGE
                     LLPDGQVIAPHRALNVARAVA"
     gene            complement(17935..18399)
                     /locus_tag="SSBG_RS12235"
                     /old_locus_tag="SSBG_01037"
     CDS             complement(17935..18399)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571583.1"
                     /locus_tag="SSBG_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01037"
                     /product="DUF6302 family protein"
                     /protein_id="WP_008746446.1"
                     /transl_table=11
                     /translation="MLTAAATLPRRPAVSLRPAAEAYDYEYFRSRLAEPALLADAVAVR
                     VFRAPLLAVPAGGPRRGGYMSFDLLTHATATHALLAEHPGFPRLRVRWSPYRETCHTVE
                     WGDPAPDWREDDAVFGRFYGYSDAAIAAFTQRHHQTPPSATPAPCSPTAP"
     gene            complement(18393..18851)
                     /locus_tag="SSBG_RS12240"
                     /old_locus_tag="SSBG_01036"
     CDS             complement(18393..18851)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380189.1"
                     /locus_tag="SSBG_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01036"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_008746447.1"
                     /transl_table=11
                     /translation="MSLTALVPENDVVPPPANEPGVPKWTPPLDAGSLKLVLERITAWK
                     PLDVEAIFDDLDMTIGNQPPPVAATGALIERLRDHLKRLSDIAVADKQFAPTVEMARLV
                     ELGRPMRDERTPADHQKAVGFARRLAFVTSDLVDELIEARYIKGQIEC"
     gene            complement(18891..19364)
                     /locus_tag="SSBG_RS12245"
                     /old_locus_tag="SSBG_01035"
     CDS             complement(18891..19364)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="SSBG_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01035"
                     /product="ATP-binding protein"
                     /protein_id="WP_008746448.1"
                     /transl_table=11
                     /translation="MELLVDTRERDASVRATSRSVDGQLDMSFNVRAEDLGTVRDIVAA
                     HLCWWRVDNGTAFRMLTVVNELLTNVLQHTPADADGCRMASLLLQKVPDGVTAIIRDQD
                     PHPPVYSSPDPLAEEGRGLMLLRALADDASVSMTSAGKDVWVFIGTPESTEHF"
     misc_feature    19420..19435
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.36"
                     /tool="antismash"
     misc_feature    complement(19457..19473)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     gene            19540..20931
                     /locus_tag="SSBG_RS12250"
                     /old_locus_tag="SSBG_01034"
     CDS             19540..20931
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031332.1"
                     /locus_tag="SSBG_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01034"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_234010501.1"
                     /transl_table=11
                     /translation="MKQLVPGASPQEWFGSELRRLRLEQGLSAKALGRLVQVSDDMILS
                     IEKGKYPSCRRDVVQRLDDALGTGGLLDRAWRMVFGDGDADKKRADADKASARRGEVRV
                     QAPAGRILGGDEPTLRPGSHEPVIRRSFLGIGGLAAIAPLNFTDVFAPAELSLPTHVNP
                     SHVDQVLAVANALSSMDNELGGGGVVRDVAARAMQWSAGLLQAQFPEHLRTDLFAAVSR
                     LGIVVGASAFDAYHHDEATKTFRFAADCAEEAGDWHLRAKTYSFLARQAVWIGAPDDGL
                     TYAEKGLVRSDRLTATEQAMLHTARARAFGKMGNVRDTMAAVGAADEAFTRARPAEDPS
                     WMAYYDEAQHNGDTAHALFDLAILAGQDPGRAARRFDTAVKGHADAYKRSRAISRTKLA
                     SLLMAKGDPRQAAALGHDALNEVGRLTSRRAADDLRQLGRFASKHRTVQEASALRDRIA
                     ATVSA"
     misc_feature    19642..19644
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20928..21815
                     /locus_tag="SSBG_RS12255"
                     /old_locus_tag="SSBG_01033"
     CDS             20928..21815
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031333.1"
                     /locus_tag="SSBG_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01033"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_008746450.1"
                     /sec_met_domain="APH (E-value: 1.4e-21, bitscore: 76.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSAAAPARHALKQACSAVGLDSAGAEPLRLAENQIWRLPHQGV
                     IVRIAREGQSAAAAREVRVARWLDQENVPAIRLVDVEQPVEAGGRPVTFWAELPPQEHG
                     SVEDVAQLLAQLHSLPTPDIELGYLDPFIRVDERLQAATTIRDDDKEWLRALHRDLAAA
                     WAERPAGLPDRAVHGDAWPGNIVRTADGVLMMDLERFSVGPPEWDLVSTAVRAKTTGAV
                     SSGEYDRFCAVYGHDVAAWEGYPILARARELRMVTYAAQHAASNAEWRSQAQFRIDCLR
                     GRSGPRPWSWRGIL"
     gene            complement(21905..22192)
                     /locus_tag="SSBG_RS12260"
                     /old_locus_tag="SSBG_01032"
     CDS             complement(21905..22192)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002502.1"
                     /locus_tag="SSBG_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01032"
                     /product="hypothetical protein"
                     /protein_id="WP_037869583.1"
                     /transl_table=11
                     /translation="MVAPRAAGAGRGLTSDELLALPAVIDLDTSNKALMIGRSTGYGLA
                     KQGEYPVKVLRLGNAYRVVTADLLKLLGLGHRHSGGSQEASDSERHGLAA"
     gene            22284..22943
                     /locus_tag="SSBG_RS12265"
                     /old_locus_tag="SSBG_01031"
     CDS             22284..22943
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062504.1"
                     /locus_tag="SSBG_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01031"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_008746452.1"
                     /transl_table=11
                     /translation="MTPDQWSTAFTGRIAQRLRDSRRAAGLTMAEVAQECAARGMPEIT
                     EHSIKNLESGRKTSVSVADVVMLADVLDVPPVTLLFPLGSSAAVEVLPGRELSTWDAVA
                     WFTGETPLDDAAPEGSPRDVLDSFRHHGDLVAASMSSYDLAQERRRVASTTLDRSRRTT
                     LLERAEGYEAHAFEDAQELRAYRERMRQRGLTPPALPDRLAFVDEPHIHPEAEERE"
     gene            22940..24556
                     /locus_tag="SSBG_RS12270"
                     /old_locus_tag="SSBG_01030"
                     /pseudo=""
     CDS             22940..24556
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143577.1"
                     /locus_tag="SSBG_RS12270"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01030"
                     /product="tyrosine-type recombinase/integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKGTITRRCRCTDPETGKDLGASCPKLQSRRHGTFGVFQELDPA
                     QDGRRRRFRRGGFETSTKAQEELGKVRALMAIPEEDDAWGRTQISDLLEDCVKEKTPLP
                     DYDETRRRFQTGQSLNSKTTVGEWLDTWLAGRKRLRRGGASRYECDIRVHLKPHLGHLR
                     LDKLRVHHIDKMFDAINERNIEIQEQNAQRRAVADELKATPNKGAENRARRKWFRAQLD
                     AMPPFRRVTGLNTQPHIRDTLRAALNVAIAQQVMPAFNPAAHVELLPGTKPKALV"
ORIGIN
        1 cccggcggcc agtgcgcgat ccaccaaccc aacctgttcc cgaggctgcc gacgctggcc
       61 aagctgttca cggcggacta ctggatcgtc ctggacgacg tgcagttcac ccgccgcgac
      121 taccagcacc gagtgcgcct cgccgccttc taagcgccgg accgccagca gtggttctcc
      181 ctccccaccc acctcccggg cgggcgatcc actctcatcc gggaagcgct gctcgacgac
      241 accgaactcg cccgccgaag ggtcgccgga atatgctgcg gcagaacttc ggagccagcc
      301 cgtactggca ctccctcacc cacgtcctgg acccggtgct ggatgccctc ggccggatcg
      361 cggtggtcgc ggagacgtcc acccgcgtgc tcctcgacct gttcggctgg cggggcagga
      421 tgctcagcag cagcctcctg gccgccagac cgggccgctc ctcgcgactc gccgacctgg
      481 ccgccgcgac gggcgctcgc gcgtacctgt gcgggaccgg cggcatgacc tacctcgacc
      541 ccgccccgtt cgccgccagg aacattcccg tggccgcctt ccggcccccg accaccggca
      601 tctggtcgac cgcacgccgg ctcagctccc tgtacgccct ggcggctctc ggcccggaca
      661 ccctggctgc ccgcctccgc tcggttgccg acgacaatgc cgcactcgcg gccgctaccg
      721 ccgggtacgg ccccctcgct cgggagcggt aacagacacc ggtggacgcg gctgcaccga
      781 ggccgtaccg ctggcggctg gtatcgattg cgtcgagcgg agccgggcgg cttctgctcg
      841 aaggttgcgt acggggtttg ctgcgcttcg ggaaaacccc tccagagtta cgcggcgaac
      901 aagccggtga ggtctgggcg gtgcggctct cgcgttgtct tccacagatg tggacgccga
      961 aagtcggtgg ctctgcccgg gtggcgctcg taagggtggt tccggtcacc gctcgatcgg
     1021 gttcagcgtt actgcttacg agttggtgcg tgataggggg tgaggtgtgt ttgccctgct
     1081 cacggccgtt ttcagatgct ggtgttgcgg tcggagacga ggccggcgat ggcgcggtag
     1141 gtgtcgggca ggcggtcgcg gcgatgtgtc cagcgggtca gttgcttcca gcgtttgtga
     1201 tcagcgaggg cgtgttcgac ggtgatgcgg tcggacgagt ggccgtggcg gtcgcgtccc
     1261 cattgttcga ctctgtcggg cagtgctccc ggccggggtt ttctcggcgg cgtgatcgcc
     1321 tgcccgcgat ggtcgcggct cagccccagg tagccgtcgt ccaacaggac ctcgacgtcg
     1381 gggaagtgct ggaagcagat ggcgatgcct tcgtcgcggg cggcggtggc gtcgtgcata
     1441 cgcccaggtc gtagggcatc ggtccataac gtgcggcccc gccagccggc gatcacggtg
     1501 gccttcatcg tgttctgctt cttcttgccc gagacgaatg cgcgccggcc gccgcggccg
     1561 gccggtggcc ggcggacccg gatctcggtg gcgtccagac acagctcgac accttcggcc
     1621 tgcgcgtagg caaacacatc cgccagagtc cgaagccgca ggccgggacg gtcgggaacc
     1681 gcgcaccccc gctccgccaa gagcgtgcgc acctctccga tcgcccgggt gaccgtggat
     1741 cggtcgacac ctgacagcag ccccagcacc gagtgcggca ggtcgtgccg caggtggatg
     1801 agtgtggcca ccaaccggtc gacgaacacc agctgatggc gggcgccggc gccttcggcc
     1861 cgcttgcggg ccccgcctcg cacagcatgg cggcgaccct cgaccccggc ctgccacggc
     1921 tcggccaact cttcgaccaa gcacgcaaga tgacgccggg agagccccgt gaacagtcga
     1981 tgcgccagca ccgcccgatt gaccatgatc gccacagcgg gatcatgcca tccacgtggc
     2041 acgacacctc acccgctatc acgcaccaac tcgttagtga gcaagttcga agtcgtgatg
     2101 gtgaagcgcg cgtccttcat gtggtgcgcg taggtggagt cctcgccacc cagcgtgcgc
     2161 agccagggaa atacgccgtc gcgtacccgc gtgagcatgt tctcggggga ctcgttgatg
     2221 aacacggacc agcgcaggat ctgggtgtcg tctgcgtaga tcgggttctc gaccggacgg
     2281 cctgtgcggt tggccttgtt ctccttggcc tgctctagga tgtcgaggcg ccggatgaac
     2341 atcaggtagg tgatctgctc gatgacctcc agtgggttgg agatcccgcc agaccagaag
     2401 gcgtcccaga gtcggtcgat cttgctcttc agctcacctg taatcacgca agcaggctag
     2461 cgtgtccctc tgacacatgg cggcccgatc ggtagtcggt gcagtgcgcc aggctcgtgt
     2521 cagaccgtcc tggcgtgcag aaagcccagc gtggtgagcc cttcgttgcg gcacaggtgg
     2581 tcggacgcac cgccgacttc ggtctggagg agttggtagg tcgcgccgtg tgtctggccc
     2641 cagtgcatgg cggcacgcca caagtgccgg ccgagaccgt gcccgcgcgc gtcagggtct
     2701 acggcgaagt actgcggcat gagctgggcc atgcccgtgg ggtcggggca gatctccatg
     2761 gggccgatgg caccgacaac acggtcctcc agcacggcca cgaggaccgg gccgcatccc
     2821 ttggccctca tctggcggtc gaggaaggcg aagccgtcgg ccgccatggt ttgggcgaag
     2881 gtggtgaagg tgcggcggac ggggaggggc cagtcttcga gccgccggac ggggccgacg
     2941 gagggggagt agtgccgcgc cgtgaagtcc tggagctgga tgcggacccc acgaggatgc
     3001 ggcgtctccg ggcccaacgg ccggacaacg cgcgcagtgg ctgctccgtg aactgccgcg
     3061 agctttcccg cgagctcggc ggcctggtcg aggacgtctc ctcgttgacc gtaggcgaag
     3121 actttcactg ttcgcccgcc gcgggtcagc agggtgggga tgagcgtgtg gtcggggtga
     3181 tggaccacat cgttgacgag gacagcctcc tgcttctccg cgccccagcg gcggtccttg
     3241 tcgtacggca ggaagtggca ctctgaggcg gccgccacca gggtggcttc gaagaggtcg
     3301 accgtcaggg cgtgcgggtg gacggggccg agggtgggca cgaccggtgc ggcgagcgcg
     3361 gggcggagcc agtcccagcg gaagaccatg cgggcacctt agcgctgtat gtgagggcgc
     3421 tccggcccgt cggtggacgg gccggagcgc gtaggtcggg ttgtggtcag aaggggttgt
     3481 cgtcgccggc gtcgcaggag cactcggcgc tctcgacgac gtcgtcgagg tccgcgacga
     3541 gtgtcacggc ggccgaggcc accgggggcg ccgcgtggcg ggcgctgctg ggcggggcgg
     3601 tcaggatctg taccggtacg ggtccgggcg tcatgggggc accgtctctt tctgtgggtc
     3661 tccgtgctgg cagtagctgt gcagtggcgc cttcgcctcc tggtagtgct tggccagggg
     3721 gcggcagact cggcaggtgc cggacagggc gcagccctcg caccctccgg tgcgaagcat
     3781 caggcggtcg gcgatcgtgc cgagccgtcg cagtccttcg acgccttcgg ccatgaggtc
     3841 gatctgctcc tcgcggccga ccttgcagat cgagaccttg gcgtgcgggt cggcgtggaa
     3901 gaacgtgtgg cccgcgttgc atccagcgaa cggcttgcgc cggcggaggt ggtcggcgga
     3961 ctgggcgagg aggggttcgc cgccgccgta gatggtcggg gtcatgttgg tgtacgcgtg
     4021 gtgctccacg ccccactccc gggcgagcgc ggccatcgcg tcggcctcgc gggcgttgtc
     4081 ctccgtgacg acgacgttga tacggagcgg cagcccggcg gcgcgggcgg cgtgcatgcc
     4141 gcgccggaac gccttccatg ctccgcgccg ctgggtgagc gcgtcgaagg actcctcgct
     4201 cgcgccgtac atgctgacga cgaggcggta aggcgggcac tcccggaaga gctggagcag
     4261 gtcgggacgg gagagcaggg agccgttggt ggagatcgtg agcatcatgc cgctgagcca
     4321 ggcgtaccgg taggcgttct ggaagtccgg gtccatggtc ggttcgccgc cggtgatctg
     4381 gagccagatg acgccggcct cgcgcatgat gtcgaggagt tcgaccttgt tctcccaggt
     4441 gaggccggag aagggccgtt cgccgaggta gcagtgcttg cagccgaagt tgcacccgag
     4501 gtttatctcc caggaagccc ggcagtatcc gtacgcggac ggttcccgga tcaggaccgt
     4561 gtgcttcgtc ggggcaccgg cgacatcgag gccccaggcg tcggccgcca gctcgaccgc
     4621 ccaggacggc aggggctggg cgtttacggc ggcggctcgg agctgctcgt agtgggtggc
     4681 cgggatgcgg gccccggatc gggctccggg gcggagcagg aggtggccgt cgaggaaagg
     4741 ggcggcgatg agctggtgca tggcgttcct ttcgcgggtg ggttcagcag tgcagggagc
     4801 agtccgggca cgcgcagccc gagagcgggt ccgtaccgct gccgccgcac gtcgggcaga
     4861 cgtcagcgcg cggcaccgac ggcgagagct gaatgcgccc aaacagcagt cggtcggacg
     4921 tgagagcggc atccaggtag gtgtcgaggc gagcggcgtc cgcggactgt ggcagcgcgt
     4981 cgagaccgag cacgaggatc gcctcgctgg tgcgggcgac cagttcgttc caggagcggc
     5041 gagtggggag ggggagtcga cgggaagccc cgggcacgtg cagcagcgcg cggtcgccga
     5101 cgagccgcag acgacgtccg agacgcggga tgacttcacg ggctccggtc agtccaccga
     5161 ggcatccgga caagcgccgc atgtggtcct cggtcgtcgc agcggtgccg ccgttggtcg
     5221 gggccggagt gtgcgtgatc aggatgcgtg cgatctcgcg gttgtccggt ccggcaccct
     5281 tccaggtcca ggcggcgaga gagacgtgca ggcgcagttc agggctcggt gggatgagag
     5341 cgatgctcat gctgccgtcc ctcccggggc tttgaagcac gaccagacga tcttcccgag
     5401 cggggtgcgg tcctccacgc cccagccgtc ggcgagcgcg gtcaccagga tcagcccgcg
     5461 gccgacggtg tccgtgtcgt cagggcgacg agggtggggg cgtcggctgc ggctgtcgtg
     5521 tacttccagg cgcacggcct cgtcatcggc gtcgattttc acgaggaagc ctcggccggg
     5581 ggccgccccg tggagcacgg cgttggtggc gagttcggag acgcagaggc ggacgtcgtc
     5641 gcctcgttcc agcaagcccc agctggtcag ggcctcggcg gtgaacgtcc gtgcctcggc
     5701 gaccgactcg ggccgggact cgaagaaccg ctgggtcgtc ttggtcatcg cgatggtcct
     5761 catgacagtg acgtggcgtc tacgacgcgg gtggtgcccg agtgcgggcg gtgaaccgga
     5821 ccgcttcggg gaacggtcga gggcgtggga cgcgcccgtc ggaccagcaa caaccgggcc
     5881 ccggcgcatt cgatttggcg tccccgttcg accgccacgg ccttcgggcc caggtgggac
     5941 atggcgggga cgacgacgcc gtagacgtcc ggcagcgcga gcgcgtcgag gagaccgttg
     6001 aacgccgccg aagcggcccc ggtggcctcg cgatcggtga agagaccgga cagccgcagc
     6061 tcgtgggcgc ggcagtactc ggccagcgag gcggccagcg cgttctgccg tgcgcgaggt
     6121 acgcgtatca accggaggaa tccgtagacg accgggccgc tgaccaggcg gtgttcggtg
     6181 aggggttcca tgttcaggac cgtccaatgg ctcgactcgt ggtgacgcat tgagcatgtc
     6241 agcgacccaa ctcgcgcgga atcgacgctt gttctacttc cgttccactt ccgtcccggc
     6301 gcgtcctcgg gtctgcttcg atggctggtg gaagggagcg acgcgtggcg accgtgcatc
     6361 actggaccgg gcttgaggcg aaggcgctgc ggctcgccct gaggctgagc gtgcggtcct
     6421 tcgcggagcg tcttggcctg gcggtcgcga ccgtgtccaa gtgggagagc aagctcgccg
     6481 ccaccgagcc gaggcccgat acccaggcca tccttgacac ggccctcggg cgggcggacg
     6541 cggcggtcca cctgcgcttc gagactctcc tgtcggagat ggccggctcc gtcgcgaccg
     6601 ccggcagacg tgtcaccccc tccggacccc gggcgtggga gtacgagtca tgggccgatg
     6661 acctcgaccg cgtcgtggtc gccctgtccc ggcaggactt cgccttcgcc gacagccttc
     6721 tcacgcggtg gctgggcagg ttcacggccc acgagctgga tgagaagggc ctgtacctct
     6781 tcggccgctc ctccaccttg ctcggcgacc tcaagcgcga tcaaggcgtc gttctgggcc
     6841 cgctctcggc gcagcactcc tacaacggtg cccggacggt cttcactcag ctcgacatcc
     6901 cccgccgcgt cgcccagctc gatctgtcac tcgcggtcgt caccgagatg tccggcaagc
     6961 tggaagtcgc tgcccatagc tacgagtccc tcgccgtcga cgaccgcctc tcacgccgcg
     7021 accgggctcg cgcacgcctg tgggtgggaa cggcgctgag caaagatggt gagcacgact
     7081 acgcgacccg cgtcatgcag gcggcgaccc gcgagttcga agacctcacc gaaccggagg
     7141 actggtcggt cgcccatcag aagctcgctc tggcccgccg tggcgtcggc gatctctcgc
     7201 aggccctgca cttcatcgat atcgcccgaa gcagcgggac gaccgactca cctatgcaac
     7261 gcgtacgtct ggacaccgct catggccaca tcctgctttc cgatgcggcg acccgggatg
     7321 atggagtcct cgtcctcgat cgggccgcca gggtagccgc gcagtacggg ctcgtgcacc
     7381 aactgcgcag cattgagggc atcagggcca tgagtgaggg gctgaccggc ccccggcaac
     7441 ggtgaccagg gagaaacgcg tgcgcaacga ccagcagggc atcaccgagg accagtggca
     7501 ccaggccagg ctgatctggg actaccacca gatgcagcac gagctgcgac ctgtcgacgt
     7561 ggcaatcggg ctgggaagcc acgatctcgg cgtcgcgacc cgctccgccg agctgtaccg
     7621 tgccgggctc ttcgagacgc tggtattcac cggtggcaac agccccacca ctgccaaggt
     7681 ctttcctcgg ggcgaggcga tccactttcg tgagcacgcc atcgacctgg gcgtccccgc
     7741 cgatgccatc ctgttggaac cgcacgctgc caacactgga gagaacatca cgctctcccg
     7801 cgaagtcctt gccgcctccg gtatccatcc ggccacggtg ctgctggtct ccaagccgta
     7861 catggaacgg cgatcgttcg cgaccgcccg caaactgtgg cccgatgtcg agttcctgtg
     7921 cgcgtcagag cggttggagt tcgacgacta tctgaggagc atcggggacg agaagctcgt
     7981 tctcgacatg ctggccggcg acctccagcg ggtcatcgag tacccgaagc tcggattcgc
     8041 catcgagcag gaagttcctg aggacgtaca tgcagcgtac gaatctctca ttcgttccgg
     8101 cttcaccagc cgcctcatcg cctcgtgagc ggcctgcttc cggcggccag tgcgcgatcc
     8161 accaacccaa cctgttcccg aggctgacga cgctggccaa gctgttcgcg gcggactact
     8221 agggagcgta ttcggttgtg atcaagaggc tgctcgtgtg aggtccttga tccagatcat
     8281 cgaggcgcgt aggtagagtc cggcgaggta gctgtcgggg gtcttgtcgt agcgcgtggc
     8341 gatgcctcgc catgccttga gcttgttgat cagacgcttg acggtgttcc gctccttgta
     8401 gaggtctgcg ttgtggctga cgggccggcc gccgtgggag cccttcttgt tccggttggc
     8461 ggcctggtcc ttcttctccg ggatgaccgc tttgatacgg cgtttgcgca ggtgggcacg
     8521 gttgccgcgg gacgagtacg ccttgtctgc ggcgaccgcg tccggccggg tgcggggacg
     8581 gccgacgagc ccgcggaccc gtaccttccc cagcactggg atgaactgcg gactgtcggc
     8641 ggcctgcccc tcggtcagga tgaacgccag cgggcggcac ctccggtcgc cggcgacata
     8701 gatcttgctg gtctgcccgc ccctggagcg tccgagcagg gcggccttca gccggagttt
     8761 gcgtcggcgc cggacgcgcc gtcgttcttc ccgcccggga tcgctcccgg cctcctgccc
     8821 ggtttgttcg tcgcagccgc ccccttcgac ctggccttct ccgcctcggc ggcagccttc
     8881 tccagagcgg tgaggacctc ctcgtccagg tgcatgccgg ccgcgtcgtg atgggcccgc
     8941 gcggtggtgg agtcgatgct gaccagggac aggtccacct caccgcgctt cgcggcttcc
     9001 gcgatcaggc cctccagcag ggcctcgaag accccggcgt cacgccactg ccggaagcgg
     9061 ttgtggacgg tcgaccaggc gccgaactct gccggcatct cccgccactg gccgcccgtc
     9121 ttgaaccgcc agatcacgcc ctcgaactgc tgccgcagcc gctcggggta cgggccgtac
     9181 tcgccgatcg gcaggtacgg cccgatgaat cccactccgc atccgtcagt tgcatacgag
     9241 tcacccatga aggcctaccc gcccaggacc caccacgcag gcaaaacccg cagattgatc
     9301 acgaccaaat acgctcccta gttgagggga aggcgcgtga acagagcgct tcgcgttgcc
     9361 tattgcgggc tgcgcccgtg ggacatggac cgtctgtacg gcgtatccgg gttccacttg
     9421 aggcccgggg cgtgcataga aggggcaacg tcactgctca ccagccaccc ttcgcagcca
     9481 gcggtgcgtc tggcgccggt ttgccagcag caccacttcg gcgcccgagt tgaactcgtt
     9541 gatcttcgcc atcacgcggg ggcgcatcat gcgccggtac gtggcgacgt acttgatcac
     9601 gccccagtga atgcggttat gcaccccgtt gcccttgtgc ccggctccgt gccggacctg
     9661 ccgggagaag atcccgtaca gcgccgccac ggtcgacacg tccatcagga ccactgtgtc
     9721 gcaagcttcg agccgtacct gcagcgtcga gttgtagttg ccgtcgatca cccaccgcgg
     9781 ctccgcgacc agctcgctct gcactcgggt gaactcgtcc atgggcagcg cgttccactc
     9841 gtcgtcgcag aacacggcat ccaggtgcgt caccggggca ttgagaatcc tgccgagatg
     9901 gcgggccacg tgggacttgc cgctgcctgc gcagccgacg atggcgacct tcttcatggt
     9961 gctccagcgt agagacaaca agtgctgggt cgtagcgtcg tcatactccc tggctcccct
    10021 ggtgatcgac gccgtgcagg atggccgccc gggctgccca ggccaggatg ctctgccctc
    10081 gcatggacag gcccagccgg ttccagtgga agatcacgtg gtagctgagc acctgccgta
    10141 ggccgcggtc cagcgtcccg acctgtacgg cacggcgaag ttcttgcccc gtgctgcgga
    10201 aggcgccgac ccactcggag acgggctcca gcagtccgcc ggggcgcagc aggacgtcgc
    10261 tgtcagcgaa gagcaggggc cggatctctt gggcgcgggc gtcgagccgg tcccctggga
    10321 cgtcgccgac ggccgagcgg tgctcttccg tgatgacgcg atgccagacg tccccctgct
    10381 cgtaccactc caggccggcg gcgcgcatca tgatcgtgca gaggagaaca gacagctcgc
    10441 gcggccccac agccaggtcc ccacgttatc tgagttgcgc cgcctctcgg ctgtcggtga
    10501 tgaacagggc gtgcgcggcc gtcatgctgg cctcgccccc gaatgccgca gtctcgggct
    10561 cgtagatccc gggccaccag cgcgcgaggt gcccgtcggc cacaaggcgg tgcaagccga
    10621 gtcggtccaa gccctccgcg gcgccgatct tggcgccgat ccccggccgg acgcggagac
    10681 gtagacgcca gcaggggtgc ttcctggtgt accaccagcc gccgatgagg ccggcggtct
    10741 ccgcctcttg gagcaggggc aggacgtgca cggtgaaggt ctcgtcggct ttcgtccagt
    10801 cggtgaagtg gaggtacacc tgccaccagt cgtccgtgga agcgtgccgg gccagggcct
    10861 cccggccggc ctggtcgtag accgccaggg cgtcggacag ggtcgtcggt tccatcccgt
    10921 gctgggctgc gacttcgggg atcaacaggc tggtgagggc ggccgtgacc gcgcggtgga
    10981 tcgggctcgg ctccgtcgag atcagttgat cagcagacat gcgtcccatc cggtgttcgg
    11041 ggcctgctgc gaggcgtgag tggtcagggc gagcgcggtg ccggcgtcac cgttgatcag
    11101 gccgggctcg ggaaggccgg gccgggcgct cgtggcgagg gtgtcgccga ggcttctcgg
    11161 gagggcctgg aggcgagggt cgacggcatc agcggcggcg cgggtggcgg tctggtagat
    11221 gcccgcccag ccgtggcaca ggcccgagtc agtgacctgc gcgagctgtt cggggtcggt
    11281 caacgcccgg tacagggcgt cctcgtagaa cccctggacg tcgggagcgt gcagggcgag
    11341 tccggcgagt tgcccggctc gcgcgattcc ggtggttccg tagcaccagc tcggccgggc
    11401 gggagcgtcg tggtgggggc gcccgaggtc gaagtcgcgg cgcgagatgt gctcgggcca
    11461 ccagggaccg gaggggctga gctggcacca ggtatcgagg tgttcgcaga tgctccagat
    11521 ggcttcgcgg tggccgccga cggtgatgcc gcggcgcatg gcctgggcca gcagaaggag
    11581 cgggccggtg atgccgtggg ctgcgccgaa gttgccgtgg ccgcccggaa agtgggggga
    11641 ttcgccgcgg gcggggtcgt ggcggaccca ccagcccggc aggccgcggc cgtcgggtgc
    11701 gagggggcgg gtcagggcga cgaggtactt cagaactcgt tcgaggggga gcccctcggg
    11761 gtcggtgcgc aggaggtacg ccccgatgcc ggtgaggccg tagaacaggt cgtactcggc
    11821 gaacgcgggc aggtcgccct tgcggatacg ggtgagcgcg gcgtccacgc ggcggtgggt
    11881 caggtcagtg atgtgctggt gcagggtccg ccgcgccggt tcgtacaggt gctggaagga
    11941 cggcgggaca gtggtgagga cgaagccgag ggccggggcg ccgaggaaca gtcccgcagt
    12001 gtcggccgcg ctgatgtggc cggccgccgc ggcggtgatc caccggtggg cggggcgcca
    12061 ggagccgccg tgacggctga ccgtctcgat gtgcagcagg ctgatcccgg cggcgccgtc
    12121 ggcgagggac tgcactgccc acggctcgtc cggaggcggg ggagcgggtt gggcgaggtg
    12181 ggcggtgtac tgctccagga tcgcggtggt agcggccagc gcagtcatcg agccgccctc
    12241 cggtgctgga gggccgcggt tcgtacgagc cggatggtgg tctcctcggc gcgcgggtca
    12301 acgcccaggg cccggacgtg gtgctggtgc aggagcgacc gggcgacgtc gagcgggtca
    12361 cggtggtcgg tcaaggccgt ccggtaggtg tcgacggcgg cggcgcgggc ccgccacgct
    12421 tcgacgaccg cagggccgcc ggggagggcc gcgagcacgg agtcgccatt cggcgcggcg
    12481 agttcgagca cctgggcacg cagggcccgg ttcagccgtc ccgtgccctg ggggaggttg
    12541 cgcaccagcc actcctcggc cgccgcggtg tccggcgcca ggggggtgac gaggtgcagg
    12601 gcgctggccg cggcgagggc ctgcggggcg agcgcgtcgg tgcgctcggt gagctggatc
    12661 tgcgcgaggg cgacggcgga gtccgcggcg aacacccggt gcgcggcgtc catggctgtc
    12721 ccgtggccga accgcccggt ctgcggctgg tagggagcca ggacgagccc ggccgccaga
    12781 ccggtcccgt gcaagctgtc cgcccacctg cggacgtgct gggctgctgc cccgtacgcg
    12841 tcgggcggca ggtgcagcgt gaggtcgagg tgctggtcgg cgtccgggcg ggccatctcc
    12901 cggtgccggg tgaaccacca gaggggcggg gcgtcgccga acgcggcgag gaggctgggc
    12961 aggcggcggc tcaggatctc gtcgtagcgg cgcgggtggg cgtggagctg cgcgaggagg
    13021 acgtcgccgg cgcccggaag gtgccgatcg ggggccgctg acggggctgt gcgcggccgg
    13081 ggtacctcgg cggccggctc cgagcggccc agggagagcc agatctcgtg tgcccgcccg
    13141 atccagccgt gggcgtctgc gtccggtagc tcgcgtagtt ccaggcgccg ggtgttgtcg
    13201 aggtgggcgc gtagtacccg gaggtggacc gggtgggaca ggtcaagggg gaggcgctgg
    13261 tcgtactcga tcatggcgac ctgctccggg gcccgcagcc ggtcccgcca ggcggcgaag
    13321 gcgctctccc actcctggat cgaggctttg cggccgggca ggtcgtcggc catcagcagc
    13381 catcgggcct gcgtgaggat ggtgcggcgg tagcgcaccc gcgggaggaa cgggagccgg
    13441 gagccggcgc cgaagtcgaa tggcttgtag gcggcgaacc gtccattggc tacttcggcg
    13501 aggaatcggg cgagcggcgg ggtctgcgtg ccgccttcca gggcgtgcag gacccggacg
    13561 tcgatgcgtc ggccggtgga gagttgtacg aggtggaagc tgcgcgggtc gacggtgacg
    13621 gcgatgtcgg cgagcgggat cgtcgtcgcg tctgtctcct ggtggccgga cagctcgatg
    13681 acgtggggca gcagccgcag cgtgcgggtg acgttctcgt tgcggtggcg gcgcggtggg
    13741 aagacgagct gcgccgtgag gctgttcggc gctccgtggt acgtggcggc gagcgcgtcc
    13801 tgatgctcgg gcggcagggc gtgggcgaac cggccggcca tgctgctgcc gggccggggg
    13861 accgcggtga ggaggatgtc gaaggcgcca ctggagagtg cccgggtgct ggaggagtgg
    13921 acttcgaagg cgacctccac ccggggtacg aacagccgct cgtccttccc ggcagccttc
    13981 tccaaggcgt cgaccatgtc gtccgtcaac cgcagttcac ggccgccgtc gaggagaacc
    14041 tgctgcatca tcgcgagcag cagttcgtcg cggtcggtgc gcaccttcag ggcggctccg
    14101 cgttcggagc cgacgtatcc ggcgggcagg cccaggccgc tgtcggcgac caggtccatc
    14161 accggcacca gggcgccgac gccgtaccgg gcccggaagc ggcggtggta gtcgcgccag
    14221 tgctggtagc cgtagggctg cggggtggtg cggtagaggg ccgagacgga tgcttgcgct
    14281 tccgcgatca cggcctgcgg gagcgtggtc tcgcagtcga gggcggtgtc aatgagcagc
    14341 ggtgtcggcg tgacgggggt gagggcgcgc atccgcgtgg cgacggtgct cacgctggtg
    14401 tcggagaggg tcggctggtg cgcggacagc tcgtcgcgca gggcgtacag ctcgtggacc
    14461 aggtcccgca cttcggggat gttgtccgcc tggagtccgt cgagttcgcg gcacaggtgc
    14521 tggaaggcgt ccacggtggt catgggcgcc cagaggctgg tgatgaggaa ccgttgctcg
    14581 acaaggctgg cgagaagagc gtcgatcttc tccggcgtgg cctgcgggaa gaggtcgcgg
    14641 aggtggccgt ggagtccccg gtacgggatg ggggtccggg ccgcgtccag ggcggcggcc
    14701 accggccggg cgttgcggac ggatatctcg accggggcca ggagaacggc gtggccgtcg
    14761 gagggcgggc ccggcgctac gagccggtca ccgcgggcgc gggcggcgtt gttggcgacg
    14821 agcggtaacc gctccagtaa cgcgggggtg cgctggaggc ggagcaccat gtcagtgacc
    14881 cactcggcgt ccggccggat cgtggcgcgg tgcttgtcgc gccaccgtgc gctcgcccgg
    14941 gggccgacgg acaccggagc agtgccggcg aacaggccga gcggggtcgg ccggtgctgc
    15001 caccgcagga ggtaggacac ggtcgacagc gcggtgcggc gcacgtgacg gggctccgtc
    15061 tgcctgcccc ggacgaccgc ctcgatggcg tcggacagga cgggggtggc cagctccagc
    15121 gcactgcgga agtcctcgcg ctgccagatg cggttcagcc atccgcgggt gacggccacg
    15181 ttgtccaggt cgagggtgcg ggggatgtct gccggcccgg ggctggtggt ggcgcgcagc
    15241 atcgcaacgc cttgccacag gtatccggcg gctgctcggg aagccatgag gcccttccat
    15301 gaggcggcgc gggaggggag agggcccgtg ggccgggcga agcgcttcgc ccggcccacg
    15361 ggtgcggggt cggcctcgat caggccgggt cctcggtgaa ggaaccgcag gcggaggcac
    15421 cggtcgcgca ggtggtgccg cagccgtcgc ccgtggagca catgaggtgg ccgtacgagt
    15481 gctcggcgat gacgaccttc acgtccaggg gcgcgaagtc gtcgtccagg tccgccgacg
    15541 gtgcgacgac cgggggcggt gcgagagtag cgctcgtcat gatgtgccct tcttctccta
    15601 gttggggtgg tgcggggtta cctgactccc ggcgtcatgc cgagggccag gagagcgaga
    15661 tccggctgtg caccttgtcg atgacccggt cggccgggat ctgctcatcg ggggtactgg
    15721 ccggatagac ccggattacc gggctggggc cgccgcgccg gttggcctcc cagtcgcgga
    15781 gcacgccggc gatctcgtcg gcgaactgct ccgcgtgcgg gccgagggcg tgcacgccgt
    15841 actccaagtg cttgttgtcc tcggtgcggc gggtaacgag gtaggcgaac gtgtcgtcct
    15901 cgacagccgc gagcgcgaac cgcttgttca cggggtcgac cacgcccgtg tccgcgttct
    15961 catcgacggc catcgtgcag aagcccggca ggctgatcgc catcgccatc tggagggtgt
    16021 cgatgagttc ctggatgcgg acgctgacgc cggtccacag ctcgtggcgc gggaacgtga
    16081 cggcgttgtc gagccggtgc gggtcggccg gcaggccgtc atcgaacttg agcccgatct
    16141 ccggagtgcc gttgaccagg aggagttcct cccggtgggc ggtggagccc tgcatcggga
    16201 cgaagccgca gatcttcgcc gactcgctcg ccaggtaggg gccgtgctcg ccctcgacct
    16261 ggatgaagga gaccgaccgg gtcaggcccc gcatccgcag cggcaccacg agccggccgc
    16321 cggacttgag ctgcgcggtc caggccgggg agatgtccca ggccccggcg gtcaccatca
    16381 cgacgtcgac ctcaccgagg tccgggatgg gctcggcggc gtcaacagtg acgacgtgca
    16441 cccgaccgta cccgtggtcg tccaggagcc ggcgcgcgcg gtcggtgacc tcggggtcga
    16501 tgtcgacggt gacgacttca ccgtcctcac cgacgagttc ggcgaggtag gccgcgttca
    16561 gcccgccaga gccgatctcc aggacccgca tcccgggctt cacctgcgcc tgctccagca
    16621 tcatggcctg aatctgcggc gcggagacgg agctgatctg cacaccgtgc tcgtccgtct
    16681 tggtgatcac ggcggcgtac gtgtcgtacg ccttgtccag cggcgtgtcg gcgggggtga
    16741 actcgtgccg cggcaccttg cgcatcaccg cttcgatctc cgaggaggag atgttgccgt
    16801 ccgcgcacag ctcgtccacc accttgttcc gcaggcgggt cgcctcgtcg ggcttgacgg
    16861 tcgtgttcgt catggacttc cttcggtcgt tcgtgttcag ggggaggggg taggtcggca
    16921 cggtgtgcca gtgggccggg aggctatcgg cgaacgctct ccgttcggcg ccggtggtga
    16981 gccgcccagg agccccgtcc gtatcactca gggcccccgg cggccgtcta ggcggcgggt
    17041 acaagatcgt ccagattgac gacctcgtag ttcctcagtt cgcgtatgag ttggctcgcc
    17101 aggaaccagc ccgactgggg gtgcccgtac gccacgggcg cgtcatcgtc gtcggcaaga
    17161 aggggttcca ggccggtggc ggtgaggcgg taccgggtgc cgatgacgcc ccagggggac
    17221 gtcgcccgcg cgcggaaggc gatgtgcccc ttccgtagat gcaggcacag ctctatggac
    17281 ggtcgcaggt gcttcaggca caccggcggc tgggccgtcc tcaccggctc accagcacgg
    17341 tgggaagcgc cttccgaatt cccggcgagg aagatgtagc cctggtcggt ctcggccggg
    17401 cagaagctga cctggcaccg aagctgctcc atcgcctccc gctgccggac gggattgacc
    17461 atgcgccact gcggcctgcc cgtcggcttc ccggccgcgt tcagcgactg ggagcaccgg
    17521 gcccacagct caccgcgggg cccgcggtca gccggggtct cgtcctggta ggcgagacgc
    17581 acggcgccga aggcgttcat gctcagcgtg agttccgact ccagcccgcc gtactcgccc
    17641 tcgcgctggg tgatgtacgg gaccagccgg ggcgccgcgc tggtccgctt cacgcgactg
    17701 ccctcgccac gttgagggcg cggtgcgggg cgatgacctg gccgtccggc agcagctcac
    17761 cggtgtcctc gaagaggagc actccgttgc acagcaggct ccagccctgc tcaggccggt
    17821 gcgcgagggg ccgcgcggcc tccctgtcgg gagcctcagc cgtggggcac ggcgggttgt
    17881 gcgcacacat ggtgctcgtc ctctcgggtg ggaagtcggg ccctcttcgg ccagctacgg
    17941 tgccgtgggg gaacacgggg cgggcgtggc cgaaggggga gtctggtggt gccgctgcgt
    18001 gaaggcggct atcgctgcat cgctgtagcc gtagaagcgt ccgaagaccg catcgtcctc
    18061 ccgccaatcg ggagcggggt cgccccactc gacggtgtgg caggtctcgc ggtatggcga
    18121 ccatcgaacg cgcaggcgcg ggaagccggg gtgctccgcg aggagggcat gcgtcgctgt
    18181 cgcgtgcgtc agcagatcga aggacatgta tccgccgcgg cgcggcccgc cggcggggac
    18241 cgcgaggagc ggcgcccgga aaacacggac tgctacggcg tccgcgagga gagcaggttc
    18301 ggcgagacgg ctgcggaagt attcgtagtc gtacgcttcc gcagccgggc gcagggagac
    18361 ggcggggcgg cgaggcagcg ttgcggcggc ggtcagcatt cgatctgccc cttgatgtac
    18421 cgggcttcga tcagttcatc gaccaggtcg gaggtcacga aagcgaggcg acgagcgaag
    18481 ccgacagctt tctggtggtc ggccggcgtg cgctcatccc gcatagggcg tcccagttca
    18541 acgagccggg ccatctctac ggtgggagca aactgcttgt cagcgacagc gatgtcactg
    18601 agtcgcttca ggtggtcgcg gaggcgttcg atcaatgctc cggtcgcagc cacgggcggc
    18661 ggctggttgc cgatcgtcat gtcgagatca tcgaagatcg cctcgacgtc gaggggcttc
    18721 catgcggtga tccgctccag gaccaacttc aagctgccgg cgtcaagtgg aggtgtccac
    18781 ttcgggacgc cgggctcgtt ggctggcgga ggaaccacgt cgttctccgg taccagagcg
    18841 gtgagggaca tcgggaactc ctggggaggg ccaagtgccg gccgtggggg ctagaagtgc
    18901 tcggtcgatt ccggggtccc tatgaagacc cacacgtcct tgcccgctga ggtcatggag
    18961 acggacgcgt cgtcggccag ggcacggagc agcatcagcc cacgcccctc ttcggccagg
    19021 gggtccggcg acgagtacac cggcgggtgg gggtcctggt cgcggatgat ggcggtgacg
    19081 ccgtccggca ccttctggag gagcaggctg gccatccggc acccgtcggc gtccgcaggg
    19141 gtgtgctgca agacgttggt gagcagttcg ttgaccacgg tcagcatgcg gaacgcggtg
    19201 ccgttgtcga cgcgccacca gcagaggtgc gcggcgacga tgtcccggac ggttcccagg
    19261 tcttcggccc ggacgttgaa actcatgtcg agttggccgt ccacacttct ggacgtggct
    19321 cgaacagaag catcccgctc gcgggtgtcg acgagtagtt ccatcgctgc ttcctccgtt
    19381 ctgccagaac cccttcagca ggggtgggtt gcggtgtgta ctggtctaga accgatcagc
    19441 aaccatttag gcagagcgca ccgagaacgt gcagagcctg atgccgagag gtgaagagtt
    19501 cggcatcgac gacttcgggg acaggacatg ccgcagccaa tgaagcagct cgttccgggg
    19561 gcgtcccccc aggagtggtt cggcagcgag ctgcgcagac ttcgcctgga acaggggctg
    19621 tcggccaagg cgcttggtcg gttagtgcag gtcagcgacg acatgatctt gtcgattgag
    19681 aagggcaagt acccgagctg tcgtcgcgac gtggtgcagc ggctcgatga cgccctcggc
    19741 acgggtgggc tccttgaccg ggcgtggcgg atggtcttcg gcgacggcga tgccgataaa
    19801 aagcgggccg atgccgataa ggcttccgcg cgccgggggg aagtgcgcgt tcaggcgccc
    19861 gcaggccgca tcctgggcgg agacgaaccg actcttcgcc ctgggagcca tgagcccgtg
    19921 attcgacgct cgttcctcgg aatcggcggc ctcgccgcca tagcccctct caacttcacc
    19981 gatgtcttcg cgcccgccga gctgtctctc ccgacccacg tcaacccgag ccacgtcgac
    20041 caggtcttgg ccgtggccaa cgccctcagc agcatggaca acgagctggg tggcgggggc
    20101 gtggtacgtg acgtggccgc ccgagcgatg cagtggtcgg ccggcctgct gcaagcgcag
    20161 ttcccagagc acctacgaac cgacctgttc gccgccgtat cgcgcctcgg catcgtggtc
    20221 ggcgcctctg ccttcgacgc ctaccaccac gacgaagcca ccaagacgtt ccgattcgca
    20281 gcggattgcg ccgaggaggc cggcgactgg catctgcggg ccaagacgta ctcgttcctc
    20341 gcacggcaag ccgtatggat cggagccccc gatgacggcc tcacctacgc cgagaagggg
    20401 ctcgtgcgct ccgaccgctt gacggcgaca gagcaggcga tgcttcacac ggcgcgggcc
    20461 agggccttcg ggaagatggg gaatgtccgc gacaccatgg cggccgtcgg cgccgcggac
    20521 gaagcgttca cccgggcccg gcccgccgag gacccgtcgt ggatggccta ctacgacgag
    20581 gcgcagcaca acggggacac ggctcacgcc ctgttcgatc tcgcgatcct ggccgggcag
    20641 gacccgggcc gggccgctcg tcgattcgac acagcggtga agggacacgc agacgcctac
    20701 aaacggtctc gtgcgatctc acggacgaag ctggcctctc tgctcatggc caagggtgac
    20761 cctcgccagg cggcggcgct cggccacgac gccctcaacg aggtaggccg gctcacctcc
    20821 cggcgcgctg ccgacgatct gcggcagctc ggccgcttcg cctcgaagca tcggaccgtc
    20881 caggaggctt cagcgctgcg agatcggatc gccgctacgg tttcggcatg acttcttcgg
    20941 cagccgcacc ggcgcgtcac gccctgaagc aggcatgttc cgcagtcgga ttggactccg
    21001 ccggagcgga acctcttcgc ctggccgaga accagatatg gcggctgcct catcaagggg
    21061 tgatcgtgcg gatcgcccgg gaaggacaga gtgctgcggc agcccgcgag gtgcgcgtcg
    21121 cacgctggct cgaccaggag aacgtccccg ccattcgtct ggtcgacgtg gagcagccgg
    21181 tcgaggcagg cggcagaccc gtcaccttct gggcagaact ccccccgcag gagcacggct
    21241 ccgttgaaga cgtcgctcag ctcctcgcac agctccactc cttgcccaca ccagacatcg
    21301 agttggggta cctcgacccc ttcatccggg tcgacgaacg gctgcaagcg gccaccacga
    21361 ttcgcgatga tgacaaggag tggctgcgcg ctcttcaccg cgacctcgca gcagcctggg
    21421 ccgagcggcc ggccggtctc cccgaccggg ctgtgcacgg cgacgcatgg cccggcaaca
    21481 tcgtccgcac ggccgacggg gtcctgatga tggacctgga gcgcttctcg gtggggcctc
    21541 cagaatggga cctcgtatcc accgccgtac gcgcgaagac caccggagcc gtcagcagcg
    21601 gcgagtacga ccggttctgt gcggtgtacg gacatgacgt ggctgcgtgg gagggctacc
    21661 ccatcctcgc gcgtgcccgt gagctgcgga tggtgacgta cgcggcgcaa cacgcagcca
    21721 gcaatgcgga gtggcggagc caggcgcagt ttcggatcga ctgtctgcgt ggtcgatccg
    21781 gaccgcggcc gtggtcgtgg aggggcatcc tctgatcaag gtgttcgtgc acctcatccc
    21841 tgcaagctcc ctgcccttgc gagactggcc ggatggggct gcgccatcct tcgcggcgta
    21901 cggactacgc agcgaggccg tgccgctcgc tgtcgctcgc ctcctggctt cctccagagt
    21961 gccggtgccc caagcccagc agcttcagca ggtcggccgt gaccactcgg taggcgttcc
    22021 ctaggcgcag caccttaacc gggtactccc cctgcttcgc gagcccatac ccggtggacc
    22081 gtccgatcat cagcgccttg ttcgaggtgt cgagatcgat cacagccgga agagcgagca
    22141 gctcgtcgct cgtcagtccc cgccccgctc ctgccgccct aggtgctacc atgacgctct
    22201 cctgacgttt acgcgtgccg tagtgacgcg aaagatgtat cacggagttg cggcagcgcc
    22261 ttctcgcttc ttagggtgtc accatgacac ctgatcaatg gtcgacagcg ttcaccggtc
    22321 ggatcgctca gcgcctacga gactcgcgcc gggccgccgg cctcacgatg gccgaggtcg
    22381 cgcaggagtg cgcggcccgc ggcatgccgg aaatcaccga gcactcgatc aagaacctgg
    22441 agtccgggcg caagacgagc gtcagcgtgg cggacgtcgt catgcttgcc gacgtactgg
    22501 acgtcccgcc ggtcaccctg ctgttcccgc tcggttcttc ggcggcggtc gaggttctgc
    22561 cgggtcgcga gctgtccacc tgggacgcgg tcgcgtggtt caccggtgag acacctctgg
    22621 atgatgcggc ccccgagggc tcgccccggg acgtgctcga cagcttccga caccatggcg
    22681 acctcgttgc cgcgtcgatg tcgtcgtacg acttggcgca ggagcgacga cgtgtggcca
    22741 gcaccactct ggaccgcagt cgccgaacca cgcttcttga gcgggccgag ggatacgagg
    22801 cgcacgcctt cgaggacgcc caagagctgc gcgcgtaccg agagcggatg cgtcagcgcg
    22861 gcctcacccc tccggccctt cctgaccgac tcgcctttgt cgacgagccc cacatacacc
    22921 ccgaggccga ggagcgtgaa tgaagaaggg caccatcacg cgacggtgcc ggtgcactga
    22981 ccccgagacc ggcaaggacc tcggggcgtc gtgcccgaag ctccagtcgc gacggcacgg
    23041 gaccttcggg gtgttccagg agctggaccc cgcccaggac ggccgacgac ggcggttccg
    23101 tcgtggtggc ttcgagacct ccaccaaagc ccaggaggag ctgggcaagg tccgcgccct
    23161 catggcgatt cccgaagagg acgacgcgtg gggcaggacg cagatcagcg acctgctgga
    23221 ggactgcgtc aaggagaaga cccctctgcc ggactacgac gagacccgtc gccggttcca
    23281 gacgggtcag tcgctcaact cgaagaccac cgtcggggag tggctcgaca cctggctggc
    23341 cgggcggaaa cgtctgcgcc gtggcggtgc gtcgcgctac gaatgcgaca tccgcgtcca
    23401 cctcaagccg cacctcgggc atcttcgcct cgacaagctc cgggtccacc acatcgacaa
    23461 gatgttcgac gccatcaacg agcggaacat cgagatccag gagcagaacg cccagcgacg
    23521 cgcggtcgcc gacgagctga aggccacccc gaacaaggga gccgagaacc gggcgcgccg
    23581 gaagtggttc cgcgcacagc tcgacgcgat gccgccgttc cgtcgagtca ccgggctgaa
    23641 cacccagcct cacatccgcg acacgctccg ggccgcgctc aacgtcgcca tcgctcagca
    23701 ggtcatgccc gccttcaacc cggccgctca cgtcgagctg ctgcccggta ccaagccgaa
    23761 ggccctcgtc tgaaccgagg agcgcatcgc tcgttggcag gagaccggta agcggccgtc
    23821 gccggtcatg gtctggaccc cggagcagac cgccgtcttc ctcgacttcg tcgcgggaga
    23881 ccggctgtac ttgctctggc gactcattgc gtttcgcggt gctcggcgag gagaggcgtg
    23941 cggtgtgcgc tgggaggact actccgcgaa gcactgctcg ctggccatcg ccacgcggct
    24001 cgtccaagac ggctgggagg tccacgaggg tgcgcccaag accgacagcg gcctccggct
    24061 gatcgccctg gacggcgaga ccaacgaggg cctcctcacg cataaggcgc gccagcagac
    24121 cgagcgcgag gcatggggtg agggctggca gaacaccggt cggatcttca cccaggagga
    24181 cggctctctc ctccacccgg gcaaggtcag cgatctgttc gagcgcctcg tggaggcggc
    24241 tggccttccg ccgatccgcc ttcatgacct ccggcacgtc gctgcgacgc tgatgctcgc
    24301 ggcgggcgtc gacatcaagg tcgtctcgga gaccctcggc cattcggaca cgcggatcac
    24361 gcgggacatc taccagtcgg tccttgacga cctggcgcgt gacgccgccg agaaggtcgt
    24421 gcagctcgtc cctcatgcgc gtaaggcgct ggcggctgtt ccggacgtcg tgccgcaggt
    24481 agaccccgcg tctcgcctgc cgagggtggc gccgccacgt aaggacgacc cgacccagca
    24541 gaatcgttcc gcctgacggt ggacggagaa ggagccccgg tcagagggaa gctgaccggg
    24601 gctccggctt gtgcgcgaag ccgcttcatg gcctcgctgg gctgctcaga gagggtcatc
    24661 cacgaccgtc aacagcgctg cggcgatggc gatcagcgct ttcgcctcgt cccggctgta
    24721 gctgaacgcc gacgtcaccg cgtccttgtg aaccgctgcg ctcgtctggt cctcgacggc
    24781 gagacggatc caagcccagc gttcgtcttg cgtgcgctgc aacctgtcct tgccgccggg
    24841 ccacttccag ccgctgtggt ccttgatcca ttcaagcgcg cgacgggcct ccaggatcgc
    24901 gccttcgatg tcgtcgtcca ggagtcggcg ctgggctgag cgcaggaacc gggcgggcgt
    24961 cgcgcggggg tcgccctcca acgggaacgg gacctgcatc tcgaacgcga ccgcggggcc
    25021 gagggcggag acctgttcga tccagcggct ctttgccacg ctgaagtgca ggacctccgt
    25081 cgtgctaccg gggtagccgg gggcctgcgg aagcgtgccg gtgacctcca gttccattcg
    25141 gaggtcgccg tcgcgagcct cgttgatggc gtggagttgg gccgaggtga ggaggaactt
    25201 gaggacgggc cgctcgactc cggtctccgg cgtgaacgcg agcacttccg tgccccgtcc
    25261 gacgagcgtc cgctggtagg ggttcgc
//
