LOCUS       NZ_GG770539            21173 bp    DNA     linear   CON 16-JAN-2024
DEFINITION  Streptomyces sp. SPB074 supercont3.1, whole genome shotgun sequence.
ACCESSION   NZ_GG770539
VERSION     NZ_GG770539.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. SPB074
  ORGANISM  Streptomyces sp. SPB074
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     The genome sequence of Streptomyces sp. strain SPB74
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   3  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Godfrey,P., Ward,D., Young,S., Zeng,Q., Koehrsen,M.,
            Alvarado,L., Berlin,A.M., Bochicchio,J., Borenstein,D.,
            Chapman,S.B., Chen,Z., Engels,R., Freedman,E., Gellesch,M.,
            Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R., Heiman,D.I.,
            Hepburn,T.A., Howarth,C., Jen,D., Larson,L., Lewis,B., Mehta,T.,
            Park,D., Pearson,M., Richards,J., Roberts,A., Saif,S., Shea,T.D.,
            Shenoy,N., Sisk,P., Stolte,C., Sykes,S.N., Thomson,T., Walk,T.,
            White,J., Yandava,C., Straight,P., Clardy,J., Hung,D., Kolter,R.,
            Mekalanos,J., Walker,S., Walsh,C.T., Wieland-Brown,L.C., Haas,B.,
            Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Microbial Sequencing Center
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2009) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
REFERENCE   4  (bases 1 to 6808467)
  AUTHORS   Fischbach,M., Ward,D., Young,S., Jaffe,D., Gnerre,S., Berlin,A.,
            Heiman,D., Hepburn,T., Sykes,S., Alvarado,L., Kodira,C.D.,
            Straight,P., Clardy,J., Hung,D., Kolter,R., Mekalanos,J., Walker,S.,
            Walsh,C.T., Lander,E., Galagan,J., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform
  TITLE     Direct Submission
  JOURNAL   Submitted (25-FEB-2008) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Arachne v. April 2007
            Genome Coverage                   :: 12x
            Sequencing Technology             :: ABI
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/16/2024 01:42:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,117
            CDSs (total)                      :: 6,045
            Genes (coding)                    :: 5,425
            CDSs (with protein)               :: 5,425
            Genes (RNA)                       :: 72
            rRNAs                             :: 6, 1 (5S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 620
            CDSs (without protein)            :: 620
            Pseudo Genes (ambiguous residues) :: 0 of 620
            Pseudo Genes (frameshifted)       :: 261 of 620
            Pseudo Genes (incomplete)         :: 378 of 620
            Pseudo Genes (internal stop)      :: 38 of 620
            Pseudo Genes (multiple problems)  :: 54 of 620
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:39:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 358156
            Orig. end                         :: 379329
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            GG770539.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated scaffolds were added in May 2010.
FEATURES             Location/Qualifiers
     region          1..21173
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21173
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21173
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11173](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11173)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(378..1331)
                     /locus_tag="SSBG_RS01490"
                     /old_locus_tag="SSBG_01290"
     CDS             complement(378..1331)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0003960 - NADPH:quinone reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (18-314). E-value: 1.9e-48.
                     Score: 157.1. Matches aSDomain:
                     nrpspksdomains_SSBG_RS01490_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009070668.1"
                     /locus_tag="SSBG_RS01490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01290"
                     /product="NADPH:quinone oxidoreductase family protein"
                     /protein_id="WP_008744469.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.7e-29, bitscore:
                     100.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAWQVAETGEPERVMRLVETERPEPGPGQLLVRVLAADVNFPDA
                     LLCRGQYQIRPPLPFTPGVELCGRAEDGRRLIGTPVLPHGGFAEYALLEEAASLPAPEA
                     LDDAEAAALHIGYQTGWFGLHRRARLQSGETLLVHAAAGGVGSAAVQLGKAAGARVIGV
                     VGGPGKAEAARALGCDLVLDRHTDDIVAAVKEFTGGRGADVVYDPVGGDSYTKSAKCVA
                     FEGRIVVVGFTSGTIPAPALNHAMVKNYAILGLHWGLYARYAPETIAACHRELTRLAAE
                     GVVKPLVSERVPLEEAASAVGRVAGGRSTGRICVLP"
     aSDomain        complement(390..1277)
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS01490_PKS_ER.1"
                     /evalue="1.90E-48"
                     /label="SSBG_RS01490_PKS_ER.1"
                     /locus_tag="SSBG_RS01490"
                     /protein_end="314"
                     /protein_start="18"
                     /score="157.1"
                     /tool="antismash"
                     /translation="VETERPEPGPGQLLVRVLAADVNFPDALLCRGQYQIRPPLPFTPG
                     VELCGRAEDGRRLIGTPVLPHGGFAEYALLEEAASLPAPEALDDAEAAALHIGYQTGWF
                     GLHRRARLQSGETLLVHAAAGGVGSAAVQLGKAAGARVIGVVGGPGKAEAARALGCDLV
                     LDRHTDDIVAAVKEFTGGRGADVVYDPVGGDSYTKSAKCVAFEGRIVVVGFTSGTIPAP
                     ALNHAMVKNYAILGLHWGLYARYAPETIAACHRELTRLAAEGVVKPLVSERVPLEEAAS
                     AVGRVAGGRSTGRIC"
     CDS_motif       complement(876..935)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SSBG_RS01490_0001"
                     /evalue="6.90E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="SSBG_RS01490"
                     /protein_end="152"
                     /protein_start="132"
                     /score="24.9"
                     /tool="antismash"
                     /translation="GETLLVHAAAGGVGSAAVQL"
     gene            complement(1538..2104)
                     /locus_tag="SSBG_RS01495"
                     /old_locus_tag="SSBG_01291"
     CDS             complement(1538..2104)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310407.1"
                     /locus_tag="SSBG_RS01495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01291"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_234010708.1"
                     /transl_table=11
                     /translation="MLAGVGERLRGLRKERGMTLAALSTSTGISVSTLSRLESGLRRPT
                     LELLLPLARAHRVALDELVGTRPVADPRVRAEPIVRHQRRMYPLSRHPGGVQAYRMIIE
                     GGSREPDPRTHEGYEWMYVLHGRLRLVLGEHDLILEPGEAAEFDTRVPHWFGLLDEKPV
                     ELLVLFGPQGERMHVRARPRRKKAD"
     gene            complement(2197..3492)
                     /locus_tag="SSBG_RS01500"
                     /old_locus_tag="SSBG_01292"
     CDS             complement(2197..3492)
                     /NRPS_PKS="Domain: Abhydrolase_1 (48-220). E-value:
                     8.9e-20. Score: 63.3. Matches aSDomain:
                     nrpspksdomains_SSBG_RS01500_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010277975.1"
                     /locus_tag="SSBG_RS01500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01292"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_008744471.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-18, bitscore: 65.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATYRQPGVVLTDRMFTVPLDHERPDGEQIEVFGREVVSTARGG
                     AERPWLLYLEGGPGNAARRFVGREAWLGRALEDYRVLLMDQRGTGRSTPANRQTLPLRG
                     GPREQADHLARFRADSIVKDAELIRHHLTGGAPWTVLGQSFGGFCVTHYLSSAPEGLSA
                     ALVTGGLPSLDAHADDVYRAAYPRVERKVAAHYARYPQDVDRVRRVAEHLAEHRPVLNG
                     GYRLTVEAFQSLGIALGGGSGSHTLHYLLENAFVRTATGLQLSDSFQEAAQAALSYAAH
                     PLYALLHESIYAQDHRPTGWAAERVRTEFPQFDAGRALAGDAPVLLTGESVHPWSFTCD
                     PSLSPLRETAELLAQRTDWTPLYDAGRLARNEVPVAAAVYHDDMYVDTAHSLRTAHAIK
                     GLRTWVTDEFEHDGLRQGPVLDRLLALVRGDA"
     aSDomain        complement(2833..3348)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS01500_Abhydrolase_1.1"
                     /evalue="8.90E-20"
                     /label="SSBG_RS01500_Abhydrolase_1.1"
                     /locus_tag="SSBG_RS01500"
                     /protein_end="220"
                     /protein_start="48"
                     /score="63.3"
                     /tool="antismash"
                     /translation="PWLLYLEGGPGNAARRFVGREAWLGRALEDYRVLLMDQRGTGRST
                     PANRQTLPLRGGPREQADHLARFRADSIVKDAELIRHHLTGGAPWTVLGQSFGGFCVTH
                     YLSSAPEGLSAALVTGGLPSLDAHADDVYRAAYPRVERKVAAHYARYPQDVDRVRRVAE
                     HLAEHRPVL"
     gene            3708..4868
                     /locus_tag="SSBG_RS01505"
                     /old_locus_tag="SSBG_01293"
     CDS             3708..4868
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964372.1"
                     /locus_tag="SSBG_RS01505"
                     /note="Members of the family are the ATP-binding subunit of
                     ABC transporters for substrates such as betaine, L-proline
                     or other amino acids, choline, carnitine, etc. The
                     substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01293"
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_008744472.1"
                     /transl_table=11
                     /translation="MIRFDHVGKRYPDGTVAVHDLSLDVAEGELVTLVGPSGCGKTTTM
                     MMVNRLVEPTSGRIEVNGEDIAGVDPVALRRRIGYVIQQVGLFPHRTVLDNTATVLSLL
                     GTKRGRARERARELLDLVGLDPETFGPRYPHQLSGGQRQRVGVARALAADPPVLLMDEP
                     FGAVDPVVRERLQNQFADLQRSLRKTVLFVTHDIEEAVRLGDRMAVYGPGRIEQFDTPQ
                     TVLGRPATSYVAEFVGADRGLKRLSVTEIRPEDLEEPPLVARSEPAARAAARLRDEGAR
                     WAVVLDGSGELHGWVGVDEVSGGGERAVGELAHRMNAWVPLGAPLKQAFGEMLQHDAGW
                     VAVLDGARFLGVLTPGKLHEALRRSVDADARGVERGDVDFESVADA"
     gap             4909..5008
                     /estimated_length=unknown
     gene            complement(5039..6403)
                     /locus_tag="SSBG_RS01510"
                     /old_locus_tag="SSBG_01294"
     CDS             complement(5039..6403)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010277980.1"
                     /locus_tag="SSBG_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01294"
                     /product="carboxypeptidase regulatory-like
                     domain-containing protein"
                     /protein_id="WP_008744473.1"
                     /transl_table=11
                     /translation="MTEETPEPRGRGAALARTLAGGLWFPLLFFFGFLLCYALPFHNPT
                     PHDVRVAVSGPRAAGEIRAAFGKASPGAFDIVTARSAADARRKVLDRDTEAAFAADARR
                     PTLYLAKAEGALLEQAVTTAFRTVAERGGGQLTTVELVPTASGDTSGTGLFYLTMSLNI
                     SAYISVMMLIRAHLTRRGKLLTLACLSAFMSLVAYFIGRGLEIVPGEPLGILYLFLLSQ
                     AVAWVTYGLVPFVKQFIPGVAITLFVLLSIPSSGGAIPYQMVPAFFRALHPVFPLGNVI
                     EALHGIFYFDGKGTLRPTLVLCAWLLLGLVLVAVGAVLARRKEHERAGAAAAEEPVEDP
                     ALEAPVPHAVTPGAHDPFGERTAVLGGEVFYDDGRPVPGVFITVLAHDGRQLLKTVTDE
                     EGRWGAAGLPEDWVSVLALAKDHRPAASRVLPREGHVTRQDFVLAAPSAHAVPSA"
     gene            complement(6425..7360)
                     /locus_tag="SSBG_RS01515"
                     /old_locus_tag="SSBG_01295"
     CDS             complement(6425..7360)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105049.1"
                     /locus_tag="SSBG_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01295"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_037870957.1"
                     /transl_table=11
                     /translation="MRRAAVPLVAALLLTACSTGPSLENRNEVTAPPGDSKSLTIGSAG
                     FTESDLLAHMYKLLLDKAGYYTRLLTVSNRELYEPALESGQIDVVPEYAATFADWLNAK
                     KNGADAKPVGSPDLARTMPRLRALAAARGLDVLDPGRAVDQNAYAVTRAYAREHGLRTL
                     SDLGRAKLRVRIAAGDECATRPYCAPGLRKTYGIDLTTIDPKGLGTTQAKKAVQDGRDQ
                     LVATTTTDATLDEFGLVLLRDDKKLQNADYLVPVVNRSRAGSRRVATALGRLNKVLTTA
                     DLAGLNRRVDSWRRLPEDVARDYLNRHHLL"
     gene            complement(7411..8085)
                     /locus_tag="SSBG_RS01520"
                     /old_locus_tag="SSBG_01296"
     CDS             complement(7411..8085)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010277986.1"
                     /locus_tag="SSBG_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01296"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_008744475.1"
                     /transl_table=11
                     /translation="MNVLGDTWDWLSDPAHWSGENGIAHRLLEHVLLTLVCLLISCLVA
                     LPVALVLGHIGRGGALAVNLANVGRAVPTFAVLVLLLLTPVGRLSEGPTVIALVLFAVP
                     PLLTNAYVGMRGVDREVVRAARGMGMTGRQLLWRVELPLAAPLVLTGVRIAAVQLVATA
                     TIAALAGGGGLGRIITAGFNLASTPQVVAGAVLVAVFALLVEGAFALGERWLPVREEGT
                     AS"
     gene            complement(8082..8762)
                     /locus_tag="SSBG_RS01525"
                     /old_locus_tag="SSBG_01297"
     CDS             complement(8082..8762)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009070656.1"
                     /locus_tag="SSBG_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01297"
                     /product="ABC transporter permease"
                     /protein_id="WP_008744476.1"
                     /transl_table=11
                     /translation="MSGTPATPDDCLARNEWICGTYLTTRRHVLLDAVAQHIELTAAAV
                     GIALVIAVPLAVLARRLRWASGPVLALTTVLYTIPSLAMFSLLLPVYGLSATLVVAGLV
                     LYSLTLLVRNLLAGLRAVPEETRQAARGMGYGPLRLLLAVELPLALPAAFAGLRIAMVS
                     AVSLVTVGAIVGFGGLGNLIYQGMNTYFKAQVLTASVLCVLLAVAADLLLLLIGRLLTP
                     WTRA"
     gene            8913..9878
                     /locus_tag="SSBG_RS01530"
                     /old_locus_tag="SSBG_01298"
     CDS             8913..9878
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068410.1"
                     /locus_tag="SSBG_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01298"
                     /product="pirin family protein"
                     /protein_id="WP_008744477.1"
                     /transl_table=11
                     /translation="MSNLDTHPVPKPCGGREDVLAAPVRELLSPRRMPLGESTEVRRLL
                     PNLGRRMIGAWAFVDHYGPDDIADEPGMQVPPHPHMGLQTVSWLHEGEVLHRDSLGSLR
                     TIRPRELGLMTSGHAISHSEESPRPHAHYLHGAQLWVALPDEARHTAAHFEHHAELPHV
                     TAPGLDATVVLGTLDTATSPGTTYSPLVGADLALRAGAEASLPLDPDFEYGVLAMSGEL
                     SVDGVPLVPGSMLYLGCGRASLPLRALSDAGAMLLGGEPFAEKLLMWWNFVGRTQEEIE
                     RAREDWSAGSRFGEVRGYDGARLPAPALPPVPLKPRGRER"
     gene            complement(10001..11173)
                     /locus_tag="SSBG_RS01535"
                     /old_locus_tag="SSBG_01299"
     CDS             complement(10001..11173)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="SSBG_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01299"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_008744478.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-45, bitscore:
                     154.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKAESLDPEAPAGEDPGPAATEPAHHLRGAARRAEAHLARLCPP
                     APGPADTWIPARAAALDPATRARLAPRLHAALAVPVRHLVDAGRRRWRPGLVAAAIDLL
                     GGDSEHYGPLCAAIELAHTGSLMVDDVQDGSPLRRGSPAAHLVFGTATALNAGTHAYFA
                     FDRAVRLTAAHDPALAGRLRDVFLAALRSAHAGQGLDITGHRAEMAEAVATGDARHVLA
                     LVRLTHRLKTGAMAALGCETAALVTAADGPRRRALAAFGEALGTAYQFTDDVADPRGVR
                     HEDGATKQEGEDTRDNKVTLPLAHAVALLPGPRMRALWDTLCAPEAGERERAEVRATLL
                     ECGAAERCVREAGELLSAAWDALAPVLPDSPRTRVLRDLAWHTVLGRSGA"
     misc_feature    complement(11169..11186)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            complement(11281..12693)
                     /locus_tag="SSBG_RS01540"
                     /old_locus_tag="SSBG_01300"
     CDS             complement(11281..12693)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009070652.1"
                     /locus_tag="SSBG_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01300"
                     /product="short-chain fatty acyl-CoA regulator family
                     protein"
                     /protein_id="WP_008744479.1"
                     /transl_table=11
                     /translation="MARTYAGARLRRLREERRLSQAELARTLGISPSYLNQMEHDSRPL
                     TVPVLLKIGETFGIDASFFSARDATRLLADLREALAAPLDEGTVLPGELEEIATRAPGA
                     ARLLLDLQSRSRRLAEQLSGARDEPGEHQESPGSPHEEVRDFFYERRNYFHSLDLAAED
                     LAAELRIRPGTAGQTLAEHLEAQHGVRVATTPGPHLHRYETATRTLHLSPRLRPGQQTF
                     RMAAQLALLEYGFALDSLAAENFPRQSPAHALTRIGLAHYFAGALVLPYRDFHARAEEY
                     HYDIERLGDHYGLGYETMCHRLSTLQRPRLSGVPFSLVRVDRAGNMSKRQSATGFPFSR
                     SGGTCPLWNIYEAFTAPGRVHVQLTRMPDGSRHLWTARTVTRRGGAWGERGSTYAIGLG
                     CEVRHAGRLVYSEGLDLDNPASDTPIGMGCRVCEHLDCPQRATPPVGHTLTIDQHSSTF
                     VPYPVRAEHAPE"
     misc_feature    complement(12847..12859)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            13030..14310
                     /gene="aceA"
                     /locus_tag="SSBG_RS01545"
                     /old_locus_tag="SSBG_01301"
     CDS             13030..14310
                     /EC_number="4.1.3.1"
                     /GO_function="GO:0004451 - isocitrate lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982023.1"
                     /locus_tag="SSBG_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01301"
                     /product="isocitrate lyase"
                     /protein_id="WP_037868674.1"
                     /sec_met_domain="PEP_mutase (E-value: 3e-17, bitscore:
                     61.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKTTDRAAELTRHWAEDPRWKGIERTYSAEDVVRLAGSVREEHT
                     LARRGAERLWRQLHERDYVHALGALTGGQAVQQVKAGLQAIYLSGWQVAADANLAGQTY
                     PDQSLYPANSVPQVVRRINNALLRADQIATAEDDGDTTDWLAPIVADAEAGFGGPLNAF
                     ELTKAMIAAGAAGIHYEDQLASEKKCGHLGGKVLVPTSQHIRTLNAARLAADIAGTPTL
                     VIARTDALAATLLTSDVDERDAPFVTGERTSEGFYHVRNGMAPVIARGLAYAPYADLIW
                     VETGTPDLAQAREFAEAIHAEHPDQMLAYNCSPSFNWRAALDDDQIAKFQRELGAMGYR
                     FQFITLAGFHSLNHGMFDLARGYAEQGMTAYVDLQEREFAAQAQGFTAVRHQREVGTGY
                     FDLVSTAVNPASSTTALAGSTEAEQFH"
     gene            14550..16097
                     /locus_tag="SSBG_RS01550"
                     /old_locus_tag="SSBG_01302"
     CDS             14550..16097
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007819229.1"
                     /locus_tag="SSBG_RS01550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01302"
                     /product="malate synthase"
                     /protein_id="WP_008744481.1"
                     /transl_table=11
                     /translation="MPTLAPPRTVRVVAAPGARHEEILTPAALGFLGALVAAFGERRQW
                     LLRERRRQAHRLAAGIRLDFPLVTTPLRTDPAWRVAPPAPGLTERHVELVGPPTPEAAA
                     AAYGSGASTWTADFEDATSPAWHTVLDGHLLLKDLARTPRAGSRPTLVVRPRGWHLDEA
                     HLEYEGKPVPAALADFGLFFFHNAHALLAAGHGPYFCLPKLENRYEARLWNDVFLLAQD
                     LTGLPAGTVRASALIETITAAMEMEEILHELRAHSSGLIAGRWDYLFSLIKTFGHRTDF
                     LLPDRARLPMTAPFLRAYTELLVRTCHRRGAHAIGGMAAQAPEGEPEAIEAAFAEVRRD
                     KEREAEDGFDGSWVAHPGLVPVGWEIFRGVLGERPHQLDRRRDDVEVRAADLLAVPRLT
                     GAPGPEGVRGSVALAVRYFDRWLGGIGLLDQGGLIADAATAEIARTQIWQWLRHGAVRR
                     ETVERHLAEELSALAAEGARSDPARVRDLFAATALGPGLPPFFTRYGYDTYLAPRAS"
     gene            complement(16179..16955)
                     /locus_tag="SSBG_RS01555"
                     /old_locus_tag="SSBG_01303"
     CDS             complement(16179..16955)
                     /EC_number="4.2.1.17"
                     /NRPS_PKS="Domain: ECH (8-249). E-value: 4.9e-76. Score:
                     247.2. Matches aSDomain: nrpspksdomains_SSBG_RS01555_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009070645.1"
                     /locus_tag="SSBG_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01303"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_008744482.1"
                     /transl_table=11
                     /translation="MSVYETILVERSGRVALLTLNRPKALNALNARLMAELVGAAEELD
                     RDPDVGCLVITGSERAFAAGADITEMAPRTSVEMYLHDWFSAWDRLGRVRTPTLAAVAG
                     HALGGGCELAMLCDLLIAADTARFGQPEVKLGVIPGIGGSQRLTRAVGKAKAMDLCLTG
                     RTMDATEAERAGLVSRIVPAADLLTEALAAADTIANLSAPAVMMAKEAVNTAFETTLAE
                     GVHFERRLFHSVFAFADQKEGMAAFVGKRKPEFRNE"
     aSDomain        complement(16209..16931)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS01555_ECH.1"
                     /evalue="4.90E-76"
                     /label="SSBG_RS01555_ECH.1"
                     /locus_tag="SSBG_RS01555"
                     /protein_end="249"
                     /protein_start="8"
                     /score="247.2"
                     /tool="antismash"
                     /translation="VERSGRVALLTLNRPKALNALNARLMAELVGAAEELDRDPDVGCL
                     VITGSERAFAAGADITEMAPRTSVEMYLHDWFSAWDRLGRVRTPTLAAVAGHALGGGCE
                     LAMLCDLLIAADTARFGQPEVKLGVIPGIGGSQRLTRAVGKAKAMDLCLTGRTMDATEA
                     ERAGLVSRIVPAADLLTEALAAADTIANLSAPAVMMAKEAVNTAFETTLAEGVHFERRL
                     FHSVFAFADQKEGMAAFVG"
     gene            complement(16952..17869)
                     /gene="mmsB"
                     /locus_tag="SSBG_RS01560"
     CDS             complement(16952..17869)
                     /EC_number="1.1.1.31"
                     /GO_function="GO:0008442 - 3-hydroxyisobutyrate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006574 - valine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmsB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010268859.1"
                     /locus_tag="SSBG_RS01560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="WP_037868675.1"
                     /transl_table=11
                     /translation="MSSPGKKIGTVAFIGLGHMGAPMAANLVGAEYTVRAFDLVPAALE
                     AGVAAGAEAAASAADAVAGADLVISMLPAGRHVLGLYEDVLGAARPGTLFVDCSTIDVA
                     DARAVHALAEGRGMRCLDAPVSGGVVGAEAGTLTFMVGGGEAEFAEALPLLDVMGKKAV
                     HCGAAGAGQAAKICNNMILGVSMIAVSEAFVLAESLGLSHQALYDVASTASGQCWALSV
                     NCPVPGPVSASPANRDYRPGFGAPLMAKDLGLAANAVRAGGVNAELGLRAAEMYAAYAE
                     GRGADEDFSGIVRVLRENSGKAGE"
     gene            complement(17866..18951)
                     /locus_tag="SSBG_RS01565"
     CDS             complement(17866..18951)
                     /NRPS_PKS="Domain: ECH (19-315). E-value: 3e-32. Score:
                     103.8. Matches aSDomain: nrpspksdomains_SSBG_RS01565_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564520.1"
                     /locus_tag="SSBG_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_037868676.1"
                     /transl_table=11
                     /translation="MSGTGQNSADESPVLTSVTGRAARLVLNRPRALNALTHPMVGLID
                     TALTAWEDDDAIDTVVLTGAGERGLCAGGDIRAIFEAARGGDGREAADFWRDEYRLNAR
                     IPHYPKPYVAVMDGIVMGGGIGVSAHGSVRVVTERTRAAMPETGIGFVPDVGGTWLLSR
                     APGHLGTRQALTGTVAGPGDALRLGLADHYVPSDALPALLEALGASPAKEAVTRYAAEA
                     PPAALDADRAWIDACYAAGTVEEIVERLRSRPEEAAHADAATLEGRSPSSLKVTLEALR
                     RARAFNTLEEALDQEFRVSLACLATPDLVEGIRAQVIDKDRDPHWSPASLAGVGAEDVA
                     RFFQPLGERELGLAPTPEVTP"
     aSDomain        complement(18007..18894)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SSBG_RS01565_ECH.1"
                     /evalue="3.00E-32"
                     /label="SSBG_RS01565_ECH.1"
                     /locus_tag="SSBG_RS01565"
                     /protein_end="315"
                     /protein_start="19"
                     /score="103.8"
                     /tool="antismash"
                     /translation="GRAARLVLNRPRALNALTHPMVGLIDTALTAWEDDDAIDTVVLTG
                     AGERGLCAGGDIRAIFEAARGGDGREAADFWRDEYRLNARIPHYPKPYVAVMDGIVMGG
                     GIGVSAHGSVRVVTERTRAAMPETGIGFVPDVGGTWLLSRAPGHLGTRQALTGTVAGPG
                     DALRLGLADHYVPSDALPALLEALGASPAKEAVTRYAAEAPPAALDADRAWIDACYAAG
                     TVEEIVERLRSRPEEAAHADAATLEGRSPSSLKVTLEALRRARAFNTLEEALDQEFRVS
                     LACLATPDLVEGIRA"
     gene            complement(18948..20111)
                     /locus_tag="SSBG_RS01570"
                     /old_locus_tag="SSBG_01305"
     CDS             complement(18948..20111)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010268866.1"
                     /locus_tag="SSBG_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SSBG_01305"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_008744483.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.5e-26, bitscore:
                     91.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9.3e-26, bitscore:
                     88.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.4e-47, bitscore:
                     158.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATTTHDTLLSEDQRALVETTLDFAGDHLAPYALEWDREKHFPV
                     DVLRKAAGLGLGGVYVREESGGSGLTRTDGILVFEALATGCPCVAAYLSIHNMVGWMID
                     TYGDEAQRARHLPGLCSMDDLASYCLTEPGAGSDAAALSTRAVRDGDDWVLTGVKQFIS
                     GAGAARLYLVMARTGGAGPDGITAFLVDKDDPGLGFGPNEHKMGWNAQPTRQVILDGVR
                     VPADRMLGAEGQGFRIAMNGLNGGRLGIAACSLGGARSALDRSLQHLAEREAFGHPLIE
                     SEALRFRLADMATELAAARALLHQAADALDRKDAQAPQLIAMAKRFATDTGFRIADRAL
                     QLHGGYGYLHEYGIEKIVRDLRVHQILEGSNEIMRVIVARGLTGAAR"
     misc_feature    complement(21138..21147)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ccgggcagga ggccgccggg caccccgacg tggacggcac ggacgaggaa ggcaccctcg
       61 ctctgcccgt cgtgcgcgcc gacctgaccg aggccgccac gctgcgcttc gcggccgtcg
      121 agatcgaggc ccgcagcctg ggagcgaact gctacttcgg cttacgggtc ccaccccccg
      181 ccacgccgga ggagccccgc ccccggccgc gcgcggcccg cctgcgggaa cggctcggga
      241 gacgacggga ctgaggcggc ggcgccgagc cgggggccgt acggatacgc ccgctccccg
      301 gaggccccgc cggacatctt cgcccaacac cccggcgccc cctcgcccct cgccccgcgc
      361 cccgcgcccc gcgcccgtca gggcagcacg cagatccgtc ccgtcgagcg gcccccggcc
      421 acgcgtccca ccgccgaggc ggcctcctcc agcgggacgc gctccgagac gagcggcttg
      481 acgacgccct cggccgcgag gcgggtcagc tcccggtggc acgcggcgat cgtctcgggc
      541 gcgtaccgcg cgtacaggcc ccagtgcagg ccgagaatcg cgtagttctt caccatggcg
      601 tggttgagcg cgggcgcggg gatcgtgccg ctcgtgaaac ccacgacgac gatgcggccc
      661 tcgaaggcga cgcacttggc ggacttcgtg taggagtcgc cgccgaccgg gtcgtagacg
      721 acgtcggcgc cccgcccgcc ggtgaactcc ttgacggcgg cgacgatgtc gtccgtgtgc
      781 cggtcgagca ccaggtcgca gccgagcgcg cgggcggcct ccgccttgcc ggggccgccg
      841 acgactccga tgacgcgcgc gcccgccgcc ttgccgagct ggacggccgc gctgccgacg
      901 ccgcccgccg ccgcgtgcac gagcagcgtc tcgccggact ggagacgcgc cctgcggtgg
      961 agcccgaacc agcccgtctg gtagccgatg tgcagcgccg ccgcctcggc gtcgtccagc
     1021 gcctcgggcg cgggcaggct cgccgcctcc tccaggagcg cgtattcggc gaagccgccg
     1081 tgcggcagga cgggggtgcc gatgaggcgg cgcccgtcct cggcgcgtcc gcacagctcg
     1141 acgcccggcg tgaagggcag cggcggcctg atctggtact ggccccggca caggagggcg
     1201 tcggggaagt tgacgtcggc cgcgagcacc cggacgagga gctgcccggg gcccggctcg
     1261 ggccgctccg tctcgacgag ccgcatcacc cgctcgggct ccccggtctc cgccacctgc
     1321 catgcccgca tggccgctcc cctctcctcg cgcctcggcc gcccggccgg cgcgctcgcg
     1381 cgcccgccgc cggaccaccc gtggagcggc atactaagcg gtcggtaagg gtgaggggaa
     1441 gaccggccgc tcctgcccgc cgggccgggg tcccggctgc cgcgccgcgc cggtcacggg
     1501 gcaccggctg ccgcgccggg gcggtcacgc gccgccctca gtccgccttc ttgcgtctgg
     1561 gtcgcgcccg tacgtgcatc cgctccccct gcggcccgaa gagcacgagg agttcgaccg
     1621 gcttctcgtc caggagcccg aaccagtgcg ggacacgggt gtcgaactcg gcggcctcgc
     1681 ccggttcgag gatcaggtcg tgctcgccga ggacgagccg gagcctgccg tgcaggacgt
     1741 acatccactc gtagccctcg tgcgtgcgcg ggtcaggttc gcgcgagccg ccctcgatga
     1801 tcatgcggta cgcctgcacg ccgcccgggt ggcggctgag cgggtacatg cggcgctggt
     1861 gccgcacgat cggctcggcg cgcacgcgcg ggtcggcgac cgggcgggtg ccgacgagtt
     1921 cgtccagcgc gacccggtgc gcgcgggcga gcgggaggag gagttcgagg gtcgggcggc
     1981 gcagcccgga ttcgaggcgg gagagcgtcg agacggagat gcccgtgctc gtggagagcg
     2041 cggcgagggt catgccgcgt tccttgcgca ggccgcgcag ccgctccccc accccggcca
     2101 ggatctgctc ggacgcctcg tcgccgcccc cggcgagcgc cgcctcggcg gaccccgcgt
     2161 cgggggcgtc ccccgggcct tcggcccgcg cggcgctcac gcgtccccgc gcacgagggc
     2221 gagcagccgg tcgagcaccg ggccctggcg cagtccgtcg tgctcgaact cgtcggtgac
     2281 ccacgtgcgc aggcccttga tcgcgtgcgc ggtgcgcagc gaatgcgcgg tgtcgacgta
     2341 catgtcgtcg tggtagacgg cggcggcgac gggtacctcg ttgcgggcga gccggcccgc
     2401 gtcgtagagc ggggtccagt cggtgcgctg ggcgaggagt tcggcggtct cgcgcagcgg
     2461 cgagagcgag gggtcgcacg tgaaggacca ggggtgcacg gactcgcccg tgaggaggac
     2521 gggggcgtcg ccggcgagcg cgcgcccggc gtcgaactgg gggaactcgg tgcggacgcg
     2581 ttcggcggcc cagccggtgg ggcggtggtc ctgggcgtag atcgactcgt gcaggagcgc
     2641 gtagagcggg tgcgccgcgt aggagagggc ggcctgcgcg gcctcctgga aggagtcgga
     2701 gagctggagc ccggtggcgg tgcggacgaa ggcgttctcc agcaggtagt gcagcgtgtg
     2761 gctgcccgag ccgccgccga gcgcgatgcc gagcgactgg aacgcctcga cggtgagccg
     2821 gtagccgccg ttgagcaccg ggcggtgctc ggccaggtgc tccgcgacgc ggcgcacgcg
     2881 gtccacgtcc tgggggtagc gggcgtagtg ggccgcgacc ttgcgttcga cgcgggggta
     2941 ggcggcgcgg tagacgtcgt cggcgtgcgc gtcgagcgag ggcaggccgc cggtgacgag
     3001 cgcggcgctc aggccctcgg gggcgctgga gaggtagtgc gtgacgcaga agccgccgaa
     3061 gctctggccg aggacggtcc agggggcgcc gccggtgagg tggtgccgga tcagttcggc
     3121 gtccttgacg atggagtcgg cgcggaagcg ggcgaggtgg tcggcctgct cgcgcggccc
     3181 gccgcgcagc gggagcgtct ggcggttggc gggggtggag cggccggtgc cgcgctggtc
     3241 catcaggagg acgcggtagt cctccagcgc ccgccccagc cacgcctcgc ggccgacgaa
     3301 gcggcgtgcc gcgttgccgg gcccgccctc caggtagagc agccagggcc gctcggcgcc
     3361 gccccgcgcg gtcgagacca cttcccggcc gaagacctcg atctgttcgc cgtccggccg
     3421 ctcgtggtcg agcgggacgg tgaacatgcg gtccgtgagg acgacgccgg gctggcggta
     3481 cgtggcggcc atggtgctcc tgccgggtgg gtggtgcctg gtcgctccca gttgagcaca
     3541 cggggcgccc ggcccgcgtc gcggctcggc ccgtacggcg ggggggcggc gcgcggggcc
     3601 ggacggaccg gccgggatgc gcccggagcg ccgcgcggag atcctgtccc gtacacgaga
     3661 ggagccgccg ggatgagcac tcttccacga caggccggag ccgtccgatg atccgcttcg
     3721 accacgtcgg caagcgctac ccggacggca ccgtcgcggt gcacgacctc tccctcgatg
     3781 tcgcggaggg ggagctggtc acgctcgtcg ggccttcggg gtgcgggaag acgacgacga
     3841 tgatgatggt caaccggctg gtcgagccga cctcggggcg catcgaggtg aacggcgagg
     3901 acatcgcggg cgtggacccg gtcgcgctgc gccgccgcat cggctacgtc atccagcagg
     3961 tgggcctctt cccgcaccgc acggtgctcg acaacacggc gacggtgctc tcgctgctcg
     4021 gcacgaagcg gggccgggcc agggagcgcg cgcgggagct gctggacctc gtggggctcg
     4081 acccggagac cttcggcccg cgctacccgc accagctctc gggcgggcag cggcagcggg
     4141 tcggggtcgc gcgggcgctc gcggccgatc cgcccgtgct gctcatggac gagcccttcg
     4201 gcgcggtgga cccggtggtg cgcgaacggc tccagaacca gttcgccgac ctccagcgca
     4261 gcctgcgcaa gacggtgttg ttcgtgacgc acgacatcga ggaggcggtg cggctcgggg
     4321 accgcatggc ggtgtacggg cccggccgca tcgagcagtt cgacacgccg cagaccgtcc
     4381 tcgggcggcc cgccacctcg tacgtcgcgg agttcgtcgg cgccgaccgg ggcctgaaac
     4441 ggctgtcggt gaccgagatc aggcccgagg acctggagga gccgcccctc gtggcgcggt
     4501 ccgagccggc cgcgcgggcg gcggcgcggc tgcgggacga gggcgcgcgc tgggcggtgg
     4561 tgctcgacgg gtcgggcgag ctgcacggct gggtgggcgt ggacgaggtg agcggcggcg
     4621 gggagcgggc cgtgggcgag ctggcgcacc ggatgaacgc gtgggtgccg ctgggtgccc
     4681 cgctcaagca ggcgttcggc gagatgctcc agcacgacgc gggctgggtc gcggtcctcg
     4741 acggggcgcg gttcctgggc gtgctgaccc cgggcaagct gcacgaggcg ctgcgccgct
     4801 cggtggacgc ggacgcgcgc ggcgtggagc gcggggacgt ggacttcgag tcggtggcgg
     4861 acgcctgagg ggtgggcgca cggcggcccg gcggggggcg gggcgggann nnnnnnnnnn
     4921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4981 nnnnnnnnnn nnnnnnnnnn nnnnnnnncg ccccgcccgg tgctctcctt gagggggctc
     5041 aggcgctcgg gaccgcgtgg gcgctcgggg cggcgaggac gaagtcctgg cgggtcacgt
     5101 ggccctcgcg gggcaggacg cggctggccg ccgggcggtg gtccttggcg agggcgagga
     5161 cgctgaccca gtcctcgggg agtcccgccg cgccccagcg gccctcctcg tcggtgacgg
     5221 tcttgaggag ctggcggccg tcgtgggcga ggacggtgat gaagacgccg gggacggggc
     5281 ggccgtcgtc gtagaagacc tcgccgccga gcacggccgt gcgctccccg aaggggtcgt
     5341 gcgcgccggg ggtgacggcg tgcggcacgg gggcctccag cgccgggtcc tcgaccggct
     5401 cctcggcggc cgcggccccc gcgcgctcgt gctccttgcg ccgggcgagc acggcgccga
     5461 cggcgacgag cacgaggccg aggaggagcc aggcgcagag cacgagcgtc gggcgcagcg
     5521 tgcccttgcc gtcgaagtag aagatgccgt gcagcgcctc gatgacgttg ccgagcggga
     5581 agacgggatg cagggcgcgg aagaaggcgg ggaccatctg gtaggggatg gcgccgccgc
     5641 tggacgggat cgagagcagc acgaagagcg tgatggcgac gccggggatg aactgcttca
     5701 cgaaggggac gagcccgtag gtgacccagg cgaccgcctg cgagagcagg aacaggtaga
     5761 ggatgccgag gggttcgccg gggacgatct ccaggccgcg cccgatgaag taggccacga
     5821 ggctcatgaa ggccgacagg cacgcgaggg tgagcagttt cccgcgccgg gtgaggtggg
     5881 cgcggatgag catcatgacg gagatgtagg cggagatgtt cagggacatc gtgaggtaga
     5941 agaggccggt gccgctcgtg tcgccggagg cggtggggac gagttcgacc gtggtgagct
     6001 gtccgccccc gcgttcggcg acggtgcgga aggcggtcgt gacggcctgt tcgagaaggg
     6061 cgccctcggc cttggcgagg tagagggtgg ggcgacgcgc gtcggcggcg aaggctgcct
     6121 cggtgtcgcg gtcgagcacc ttgcggcgcg cgtcggccgc cgagcgggcg gtgacgatgt
     6181 cgaaggcgcc gggcgacgcc ttgccgaacg ccgcgcggat ctcgcccgcc gcccggggac
     6241 cggagacggc gacgcggacg tcgtgcggcg tcgggttgtg gaacggcagc gcgtagcaga
     6301 gcaggaagcc gaagaagaac agcagcggga accacaggcc gcccgcgagg gtgcgggcga
     6361 gcgcggcgcc ccggccgcgc ggctcggggg tctcctcggt catctggctg ccttcctgac
     6421 gggctcagag caggtggtgt cggttcaggt agtcgcgggc gacgtcctcg ggcaggcggc
     6481 gccagctgtc gacgcggcgg ttgagccccg cgaggtcggc ggtggtgagg accttgttga
     6541 ggcggccgag cgcggtggcg acgcggcgcg aaccggcccg ggagcggttg acgacgggga
     6601 cgaggtagtc ggcgttctgg agcttcttgt cgtcgcggag caggacgagc ccgaactcgt
     6661 ccagcgtcgc gtcggtcgtg gtcgtggcca cgagctggtc gcggccgtcc tgcacggcct
     6721 tcttcgcctg cgtcgtgccg aggcccttgg ggtcgatcgt ggtgaggtcg atgccgtacg
     6781 tcttcctgag gcccggggcg cagtacgggc gggtcgcgca ctcgtcgccc gccgcgatgc
     6841 ggacgcggag cttcgcgcgg ccgaggtccg agagggtgcg cagcccgtgc tcgcgcgcgt
     6901 aggcgcgggt gacggcgtac gcgttctggt ccaccgccct gcccgggtcg aggacgtcga
     6961 ggccgcgcgc ggcggcgagg gcgcgcaggc ggggcatggt gcgggcgagg tcgggcgagc
     7021 cgaccggctt cgcgtcggcg ccgttcttct tggcgttgag ccagtccgcg aacgtggccg
     7081 cgtactcggg gacgacgtcg atctgcccgg attccagcgc gggctcgtac agctcgcggt
     7141 tggagacggt gaggagccgg gtgtaatagc cggccttgtc gaggagcagc ttgtacatgt
     7201 gggcgagcag gtcgctctcg gtgaagccgg ccgagccgat ggtgaggctc ttgctgtcgc
     7261 ccgggggcgc ggtgacctcg ttccggttct ccagggacgg gcccgtggag caggcggtga
     7321 ggaggagggc cgcgacgagc ggcacggcgg cgcggcggat acggggcgcg cgggggacgc
     7381 ggcgtgggcg gcgggcgcgg ggggcgcggt tcacgaggcg gtcccctcct cgcgtaccgg
     7441 cagccaccgc tcccccagcg cgaaggcgcc ttcgaccagg agcgcgaaga cggcgacgag
     7501 caccgcgccc gcgacgacct gcggcgtgga ggcgaggttg aacccggcgg tgatgatgcg
     7561 gccgagcccg ccgccgcccg cgagcgcggc gatcgtcgcc gtcgcgacga gctggacggc
     7621 ggcgatgcgg acgccggtga ggacgagggg tgcggcgagc ggcagttcga cgcgccacag
     7681 gagctgccgg ccggtcatgc ccatgccgcg cgcggcacgg accacctcgc ggtccacgcc
     7741 gcgcatcccg acgtaggcgt tggtcagcag gggcggcacc gcgaagagga cgagcgcgat
     7801 gacggtgggg ccctcgctga gcctgccgac cggggtgagc aggaggagga cgaggacggc
     7861 gaaggtgggg acggcgcggc cgacgttcgc gaggttcacg gcgagggccc caccgcgccc
     7921 gatgtggccg aggacgaggg cgacggggag cgcgacgagg cagctgatca gcagacagac
     7981 gagggtcagc aggacgtgtt cgagcaggcg gtgcgcgatg ccgttctcgc ccgaccagtg
     8041 cgcggggtcg ctgagccagt cccaggtgtc gccgagtacg ttcacgcgcg cgtccacggg
     8101 gtgaggagac ggccgatcag gagcaggagg aggtcggcgg cgacggcgag gaggacgcac
     8161 agcaccgagg cggtgagcac ctgtgccttg aagtaggtgt tcatgccctg gtagatgagg
     8221 ttgccgaggc cgccgaagcc gacgatggcg cccacggtga cgagcgagac ggccgagacc
     8281 atcgcgatgc gcagcccggc gaaggcggcg ggcagcgcga ggggcagttc gaccgcgagg
     8341 agcagccgca gcggcccgta ccccatgccg cgcgccgcct gccgggtctc ctccggcacg
     8401 gcgcgcagcc cggcgaggag gttgcggacg aggagcgtga gcgagtagag gacgagcccg
     8461 gcgacgacga gggtcgccga gagcccgtac accggcagca gcagcgagaa catcgcgagc
     8521 gaggggatcg tgtagagcac cgtcgtgagc gcgagcaccg gcccggacgc ccagcgcagg
     8581 cggcgcgcga ggacggcgag cgggacggcg atgacgaggg cgatgccgac ggcggccgcg
     8641 gtcagctcga tgtgctgcgc gacggcgtcg agcagcacat gccgccgggt ggtcaggtag
     8701 gtgccgcaga tccactcgtt gcgcgcgagg cagtcgtcgg gggtcgccgg ggtgccgctc
     8761 atccgcccat tccagcgggg acccgggagg cgggcacgtc cgggcggacc gtccgggtgg
     8821 cgggcggggg cggagcgccc ggccggagga ccgtccgcgc gggggccggg ccgtccgggt
     8881 ggcgcccggt cgcgggcgtt aggttgagcg gcatgagcaa cctggacacc caccccgtgc
     8941 cgaagccgtg cggtggccgc gaggacgtcc tcgcggcacc cgtgcgcgag ctgctgagcc
     9001 cgcggcggat gccgctcggg gagtcgacgg aggtgcggcg gctgctgccg aacctcggcc
     9061 gccgcatgat cggcgcctgg gccttcgtgg accactacgg gcccgacgac atcgcggacg
     9121 agcccgggat gcaggtccct ccgcacccgc acatgggcct ccagacggtg agctggctgc
     9181 acgagggcga ggtgctgcac cgcgactcgc tcggctcgct ccggacgatc cggccgcgcg
     9241 agctgggcct catgacctcg ggccacgcga tctcgcactc cgaggagagc ccgcgcccgc
     9301 acgcccatta cctgcacggc gcgcagctgt gggtggcgct gcccgacgag gcgcggcaca
     9361 ccgccgcgca cttcgagcac cacgcggagc ttccgcacgt cacggcgccc ggcctcgacg
     9421 cgaccgtggt cctcggcacg ctcgacaccg cgacctcgcc ggggacgacg tactcgccgc
     9481 tcgtcggcgc ggatctcgcg ctgcgcgcgg gcgccgaggc gagcctgccg ctggacccgg
     9541 acttcgagta cggggtcctc gcgatgtcgg gtgagctgtc cgtggacggg gtgcccctcg
     9601 tgcccgggtc gatgctctac ctcggctgcg ggcgcgcgag cctgccgctg cgggccctct
     9661 cggacgcggg cgcgatgctc ctgggcggcg agcccttcgc ggagaagctg ctgatgtggt
     9721 ggaacttcgt gggacgtacg caggaggaga tcgagcgggc ccgcgaggac tggtcggcgg
     9781 gctcgcgctt cggcgaggtc cgcggctacg acggggcgcg cctcccggcc cccgcgctcc
     9841 cgcccgtccc gctcaagccg cgcgggcggg aacgctgagg gggacgcccg ggcgctgagg
     9901 ggcgcgggct cgcgggcggg ccccgcgccg ggccctcctc cgtccgcgcc ccgcgccctc
     9961 gcgcgtccgc tctcgcctcg cgagggtccg cgtccccgcc tcacgccccc gaacgcccga
    10021 ggacggtgtg ccacgccagg tcgcgcagca cgcgggtgcg gggcgagtcg gggaggacgg
    10081 gggcaagggc gtcccaggcc gcggaaagca gttccccggc ctcgcggacg cagcgctcgg
    10141 ccgcgccgca ctccagcagc gtcgcccgta cctccgcgcg ctcgcgctcc cccgcctccg
    10201 gcgcgcacag cgtgtcccac agggcgcgca tccgcggccc ggggagcagg gcgacggcgt
    10261 gggccagcgg cagggtgacc ttgttgtcgc gggtgtcctc gccctcctgt ttcgtcgcgc
    10321 cgtcctcgtg gcggacgccg cgcgggtcgg cgacgtcgtc ggtgaactgg tacgcggtgc
    10381 cgagcgcctc gccgaaggcg gccagggccc ggcggcgggg gccgtcggcg gcggtgacga
    10441 gggcggcggt ctcgcagccg agggcggcca tcgccccggt cttgagccgg tgcgtgaggc
    10501 ggacgagagc gagcacgtgc cgggcgtcgc ccgtcgcgac cgcctccgcc atctcggcgc
    10561 ggtgccccgt gatgtcgagg ccctgtccgg cgtgcgcgga gcggagcgcg gccaggaaga
    10621 cgtcccgcag gcgcccggcg agggccgggt cgtgggccgc ggtgagccgg acggcgcggt
    10681 cgaaggcgaa gtaggcgtgg gtgcccgcgt tgagcgcggt ggcggtgccg aagacgaggt
    10741 gcgcggcggg ggaaccgcgc cgcagcggcg agccgtcctg cacgtcgtcc accatgaggg
    10801 agccggtgtg ggcgagttcg atcgccgcgc acagcggccc gtagtgctcg ctgtcgccgc
    10861 cgagcaggtc gatcgccgcg gcgacgaggc cgggccgcca gcgcctgcgg cccgcgtcga
    10921 ccaggtggcg cacggggaca gcgagcgccg cgtgcaggcg cggggcgagg cgcgcccggg
    10981 tggcggggtc gagggcggcg gcccgtgccg gaatccaggt gtccgcgggg ccgggggcgg
    11041 gcgggcacag ccgcgcgagg tgcgcttcgg cgcgccgggc cgcgccgcgg aggtggtggg
    11101 cgggttccgt cgcggcgggg cctgggtcct cgccggccgg ggcctcgggg tcgagggatt
    11161 cggccttgtt cacgcgtcct taacgacggc tcgggtcgcg ggacgagcgg acgcgggcgg
    11221 gcggcgcgcc tcgggctcca gcggtgcggt gcccggggcg ggcccgtccg cgtggccccc
    11281 tcactccggg gcgtgctcgg cgcgcaccgg gtagggcacg aaggtgctgc tgtgctggtc
    11341 gatggtgagc gtgtggccga cgggcggagt cgcgcgctgc gggcagtcga ggtgttcgca
    11401 gacgcggcag cccatgccga tgggcgtgtc ggaggccggg ttgtcgaggt cgagcccctc
    11461 ggagtagacg aggcggcccg cgtggcggac ctcgcagccg aggccgatcg cgtacgtgct
    11521 gccgcgctcg ccccaggcgc cgccgcgccg ggtgacggtc cgggcggtcc acaggtggcg
    11581 gctgccgtcg ggcatccggg tgagctggac gtgcacgcgg cccggggcgg tgaacgcctc
    11641 gtagatgttc cacagggggc aggtgccgcc cgagcgcgag aaggggaagc cggtcgcgga
    11701 ctggcgcttg gacatgttcc ccgcgcggtc gacgcggacg agcgagaagg ggacgccgct
    11761 caggcgcggg cgttgcaggg tgctgaggcg gtggcacatg gtctcgtagc cgagtccgta
    11821 gtggtcgccg aggcgttcga tgtcgtagtg gtactcctcg gcgcgcgcgt ggaaatcgcg
    11881 gtacggaagg acgagggcgc ccgcgaagta gtgcgcgagg ccgatgcggg tgagcgcgtg
    11941 ggcgggtgac tggcggggga agttctcggc cgcgagggag tcgagcgcga agccgtactc
    12001 caggagcgcg agttgcgcgg ccatgcggaa ggtctgctgg cccgggcgca ggcgcggcga
    12061 gaggtgcagg gtgcgggtcg cggtctcgta gcggtgcagg tgggggccgg gggtggtggc
    12121 gacccggacg ccgtgctggg cctccaggtg ctcggcgagg gtctggccgg ccgtgccggg
    12181 gcggatgcgg agttcggccg cgaggtcctc ggcggcgagg tcgagggagt ggaagtagtt
    12241 gcggcgttcg tagaagaagt cgcgcacctc ctcgtggggc gagcccgggg actcctggtg
    12301 ctccccgggc tcgtcgcggg ccccggagag ctgttcggcc aggcgccggg agcggctctg
    12361 gaggtcgagg aggagccggg cggcgcccgg ggcgcgggtg gcgatctcct ccagttcgcc
    12421 gggcaggacc gtgccctcgt cgagcggcgc ggcgagggct tcgcgcaggt cggcgaggag
    12481 gcgggtcgcg tcgcgggcgg agaagaagga cgcgtcgatg ccgaaggtct cgccgatctt
    12541 gagcaggacg ggcaccgtga gcgggcgcga gtcgtgctcc atctggttca ggtagctcgg
    12601 cgatatgccg agcgtgcggg cgagttcggc ctggctgagg cggcgttcct cacgcagccg
    12661 gcgcagccgc gcgcccgcat aggtcctggc catggcaggc cccctccgtc cccgtttccg
    12721 tcactccatg tcactcccgg cgagagtggg agccacctta gcgggcgcgc gaggcttggc
    12781 aagcttcgca aagccgaccg ggcaagattc gcagacttca cagatttccc cccttgatgg
    12841 cactcagtgc cagtgccaca gtcgagtcat cgccccgacc tcgcaaggga aacaggggta
    12901 tccgagcagg gcggaatgcc ttgacggact tagtgcgaca ctgcgtgccg cacagggctg
    12961 agtccgtccc cctgcttcac aaccttgaca cctcaccacc gcgacacctc aagggagacg
    13021 gtgaccctca tgggcaagac gaccgaccgc gcagccgaac tgacccgtca ctgggccgag
    13081 gacccccgct ggaagggcat cgagcgcacc tactccgccg aggacgtcgt gcgtctcgcc
    13141 ggcagcgtcc gcgaggagca cacgctcgcc cggcgcggcg ccgagcgcct gtggcgccag
    13201 ctccacgagc gcgactacgt ccacgcgctc ggcgccctca ccggcggcca ggccgtccag
    13261 caggtcaagg ccggtctcca ggccatctac ctctcgggct ggcaggtcgc ggcggacgcg
    13321 aacctggccg ggcagaccta cccggaccag agcctctacc cggccaactc cgtcccgcag
    13381 gtcgtgcgcc gcatcaacaa cgccctgctg cgcgccgacc agatcgcgac cgccgaggac
    13441 gacggcgaca ccacggactg gctcgcgccc atcgtcgccg acgcggaggc cggtttcggt
    13501 ggcccgctca acgccttcga gctgacgaag gcgatgatcg ccgccggtgc cgccggcatc
    13561 cactacgagg accagctcgc gtccgagaag aagtgcggcc acctcggcgg caaggtcctc
    13621 gtgccgacct cccagcacat ccgcaccctc aacgcggccc ggctcgccgc cgacatcgcc
    13681 ggcacgccga ccctcgtcat cgcccggacc gacgccctcg cggcgacgct gctcacgagc
    13741 gacgtggacg agcgcgacgc gccgttcgtc accggcgagc gcacctccga gggcttctac
    13801 cacgtgcgca acggcatggc gcccgtcatc gcccgcggcc tcgcctacgc cccgtacgcg
    13861 gacctcatct gggtcgagac cggcaccccc gacctcgcgc aggccaggga gttcgccgag
    13921 gcgatccacg ccgagcaccc ggaccagatg ctcgcctaca actgctcgcc gtccttcaac
    13981 tggcgcgccg cgctggacga cgaccagatc gccaagttcc agcgcgagct gggcgcgatg
    14041 ggctaccgct tccagttcat caccctcgcc gggttccact ccctcaacca cggcatgttc
    14101 gacctcgcgc gcggctacgc cgagcagggc atgaccgcgt acgtcgacct ccaggagcgc
    14161 gagttcgccg cgcaggccca gggcttcacc gccgtgcgcc accagcgcga ggtcggcacc
    14221 ggctacttcg acctcgtctc cacggccgtc aacccggcct cctccaccac cgcgctcgcc
    14281 ggctccaccg aggccgagca gttccactga gcggaccggg acggggcggg cccactcctc
    14341 gcccgccccg tccgctcccc cgggacgcgc tccggcgcct cccgcacccg ggggcgcgcg
    14401 ccttcgcgtc ggcgcgcgtc cccgtacccc cgaggcgaac gggggccggg cacccgtctc
    14461 cgtccggccc ccgttcctcg caccccaccc ggcccggccg gggccgcgcc tcgcgccgtc
    14521 cgccccgggc ccgctccagg aggtccccga tgcccactct cgccccgccc cgcaccgtcc
    14581 gcgtcgtcgc cgcccccggc gcgcgccacg aggagatcct gacgcccgcc gcgctcggct
    14641 tcctcggcgc cctggtggcc gccttcggcg agcgccgcca gtggctgctg cgcgagcggc
    14701 gccgccaggc gcaccgcctg gcggccggaa tccgcctcga cttcccgctc gtcacgacgc
    14761 ctctgcgcac cgacccggcc tggcgcgtcg cgccccccgc tcccgggctc accgaacggc
    14821 acgtggaact cgtggggccg cccacgccgg aggcagcggc ggccgcgtac ggctctggcg
    14881 cctcgacctg gaccgccgac ttcgaggacg ccacctcgcc cgcctggcac acggtcctcg
    14941 acgggcacct cctgctcaag gacctcgcgc gcaccccgcg cgcgggctcc cgtcccaccc
    15001 tcgtcgtccg gccgcgcggc tggcacctcg acgaggcgca cctggagtac gaggggaagc
    15061 ccgtgcccgc cgccctcgcg gacttcgggc tcttcttctt ccacaacgcc cacgcgctcc
    15121 tcgcggcggg ccacggcccg tacttctgcc tgccgaagct ggagaaccgg tacgaggcac
    15181 ggctgtggaa cgacgtcttc ctcctcgccc aggacctcac cggcctcccg gcgggcaccg
    15241 tgcgggcctc ggcgctcatc gagacgatca ccgcggcgat ggagatggag gagatcctgc
    15301 acgagctgcg cgcgcacagc tcggggctga tcgccgggcg ctgggactac ctgttcagtc
    15361 tcatcaagac cttcggccac cgcaccgact tcctcctgcc cgaccgcgcc cggctgccga
    15421 tgacggcccc gttcctgcgc gcgtacaccg aactcctggt gcgcacgtgc caccggcgcg
    15481 gcgcccacgc gatcggcggc atggccgcgc aggcgcccga gggtgaaccg gaggcgatcg
    15541 aggcggcctt cgccgaggtg cggcgcgaca aggaacggga ggccgaggac ggtttcgacg
    15601 gctcgtgggt cgcgcacccg gggctcgtgc cggtcgggtg ggagatcttc cggggcgtgc
    15661 tcggcgagcg gccccaccag ctcgaccgcc ggcgcgacga cgtcgaggtc cgggccgccg
    15721 acctcctcgc cgtgccgcgc ctgacggggg cgcccggtcc cgagggcgtg cgtggcagcg
    15781 tggccctcgc ggtccgctat ttcgaccgct ggctcggcgg aattggactg ctcgaccagg
    15841 gcgggctcat cgccgacgcg gccacggccg agatcgcccg tacccagatc tggcagtggc
    15901 tgcggcacgg ggccgtgcgc cgcgagacgg tcgagcggca cctcgccgag gagctgtccg
    15961 ccctcgccgc ggagggcgcc cgcagcgacc ccgcgcgggt ccgcgacctc ttcgccgcga
    16021 cggcgctcgg ccccgggctc ccgccgttct tcacgcggta cgggtacgac acctacctgg
    16081 cgccccgcgc ctcctgaccc cacggcgggc gggacctgcc ccccgcccgc cgcggcccgg
    16141 caccgggccg tacgagaccc gcgccccgtg gtccccgcct actcgttccg gaactccggc
    16201 ttccgtttcc cgacgaacgc cgccatcccc tccttctggt ccgcgaaggc gaacaccgag
    16261 tggaacaggc gccgttcgaa gtgcacgccc tccgcgaggg tcgtctcgaa agccgtgttg
    16321 accgcttcct tcgccatcat caccgcgggt gccgagaggt tcgcgatcgt gtcggccgcc
    16381 gcgagcgcct ccgtgaggag gtcggccgcc gggacgatcc gcgagacgag gcccgcgcgt
    16441 tcggcctcgg tcgcgtccat cgtgcgcccg gtcaggcaca ggtccatcgc cttcgccttg
    16501 ccgaccgcgc gggtcagccg ctgggagccg ccgatgcccg ggatgacccc gagcttcact
    16561 tccggctgcc cgaagcgcgc cgtgtcggcg gcgatcagca gatcgcacag catggcgagt
    16621 tcgcagcccc cgccgagcgc gtgccccgcg acggcggcga gcgtgggcgt acgcaccctg
    16681 ccgagccggt cccaggccga gaaccagtcg tgcaggtaca tctcgaccga ggtgcgcggc
    16741 gccatctcgg tgatgtccgc accggccgcg aaagcccgct cggagccggt gatcacgaga
    16801 cagccgacgt ccgggtcccg gtccagctcc tcggccgcgc cgacgagttc cgccatgagc
    16861 cgcgcgttga gcgcgttgag cgccttgggg cggttgaggg tgaggagggc cacgcggccg
    16921 ctgcgctcga ccaggatcgt ctcgtacacg ctcattcccc cgccttgccc gagttctccc
    16981 gcaggacccg tacgatgccc gagaagtcct cgtccgcacc ccgcccttcg gcgtacgcgg
    17041 cgtacatctc agccgcccgg agcccgagtt cggcgttcac gccgcccgcg cggaccgcgt
    17101 tggccgcgag gccgaggtcc ttcgccatga gcggggcgcc gaagccgggc cggtagtccc
    17161 ggttggccgg ggacgccgaa acggggcccg ggaccgggca gttgacgctg agcgcccagc
    17221 actggccgga ggcggtggag gccacgtcgt agagggcctg gtgcgagagg cccaggctct
    17281 cggcgaggac gaacgcctcg ctcacggcga tcatcgagac gccgaggatc atgttgttgc
    17341 agatcttcgc ggcctgcccc gccccggccg ctccgcagtg cacggccttc ttgcccatga
    17401 cgtcgagcag cggcagcgcc tcggcgaact ccgcctctcc cccgcccacc atgaacgtga
    17461 gcgtcccggc ctcggcgccc acgacgccgc ccgagacggg cgcgtcgaga cagcgcatcc
    17521 cgcgcccctc ggcgagcgcg tgcacggcgc gggcgtcggc gacgtcgatc gtggagcagt
    17581 ccacgaagag ggtgccgggg cgcgcggcgc cgaggacgtc ctcgtagagg ccgaggacgt
    17641 ggcgcccggc ggggagcatg gagatcacga ggtccgcgcc cgccacggcg tccgcggcgc
    17701 tcgcggcggc ctcggccccg gccgcgacgc cggcttcgag ggcggcgggc acgaggtcga
    17761 aggcgcgcac ggtgtactcc gcgccgacga ggttggcggc catgggcgcg cccatgtgcc
    17821 cgagtccgat gaacgcgacg gtgccaatct tcttgccggg actgctcacg gtgtcacctc
    17881 cggtgtcggg gcgaggccga gttcccgctc gcccaggggt tggaagaagc gcgcgacgtc
    17941 ctcggcgccg accccggcga ggctcgccgg gctccagtgc gggtcgcggt ccttgtcgat
    18001 gacctgcgcg cggatgccct ccacgaggtc gggtgtggcg aggcaggcga gcgagacgcg
    18061 gaattcctgg tcgagcgcct cctccagggt gttgaacgcg cgtgcgcggc ggagcgcttc
    18121 gagcgtcacc ttgaggctgg agggggagcg gccttcgagg gtcgccgcat cggcgtgcgc
    18181 ggcctcctcg gggcgggacc gcagccgctc gacgatctcc tcgacggtgc cggccgcgta
    18241 gcaggcgtcg atccaggcgc ggtcggcgtc gagcgcggcg ggcggcgcct cggccgcgta
    18301 ccgggtgacg gcctccttgg cgggcgaggc gccgagcgct tcgaggaggg cgggcagcgc
    18361 gtcggagggc acgtagtggt cggcgaggcc gaggcgcagc gcgtccccgg gcccggcgac
    18421 ggtgccggtg agggcctggc gggtgccgag gtgcccgggg gcgcgcgaga ggagccacgt
    18481 accgccgacg tcgggcacga agccgatgcc ggtctcgggc atcgccgccc tggtgcgttc
    18541 ggtgacgacg cggacggagc cgtgcgcgga gacgccgatg ccgccgccca tgacgatgcc
    18601 gtccatgacg gcgacgtagg gcttggggta gtgcgggatg cgggcgttga gccggtactc
    18661 gtcgcgccag aagtccgcgg cctcccgccc gtcgccgccg cgcgccgcct cgaagatggc
    18721 gcggatgtca ccgcccgcgc acaggccgcg ctcccccgcc ccggtgagga cgacggtgtc
    18781 gatcgcgtcg tcgtcctccc aggcggtgag cgcggtgtcg atgaggccga ccatcgggtg
    18841 cgtgagggcg ttgagggcgc ggggccggtt gaggacgaga cgggcggcgc gaccggtgac
    18901 cgaggtgagg acggggctct cgtccgcgct gttctgcccg gtgccgctca tcgggcggct
    18961 cccgtcaggc cccgggccac gatgacgcgc atgatctcgt tgctcccctc caggatctgg
    19021 tgcacccgca ggtcgcggac gatcttctcg atcccgtact cgtgcagata gccgtagccg
    19081 ccgtggagct ggagcgcgcg gtcggcgatc cggaaaccgg tgtcggtggc gaagcgcttc
    19141 gccatggcga tgagctgggg ggcctgcgcg tccttgcggt cgagggcgtc ggcggcctgg
    19201 tggaggaggg cgcgcgcggc ggcgagttcg gtggccatgt cggcgaggcg gaagcgcagg
    19261 gcctcggact cgatgagcgg gtgcccgaac gcctcccgtt cggcgaggtg ctggagcgag
    19321 cggtcgagcg cggagcgggc gccgccgagc gagcaggccg cgatgccgag gcggccgccg
    19381 ttgaggccgt tcatggcgat gcggaagccc tgtccctccg cgccgagcat ccggtcggcg
    19441 ggcacgcgca cgccgtcgag gatgacctgc cgggtgggct gcgcgttcca gcccatcttg
    19501 tgctcgttgg gcccgaagcc gagcccgggg tcgtccttgt cgacgaggaa ggcggtgatg
    19561 ccgtcgggtc cggcgccgcc cgtgcgggcc atgacgaggt agaggcgtgc cgcgcccgcg
    19621 ccggagatga actgcttgac gccggtgagg acccagtcgt cgccgtcgcg cacggcgcgg
    19681 gtggagaggg cggcggcgtc cgagcccgcg cccggctcgg tgaggcagta gctcgcgagg
    19741 tcgtccatcg agcagagccc cgggagatgg cgggcgcgct gggcctcgtc gccgtaggtg
    19801 tcgatcatcc agccgaccat gttgtggatc gacaggtagg cggcgacgca ggggcagccg
    19861 gtggcgagcg cctcgaagac gaggatgccg tcggtgcgcg tgagcccgga accaccggac
    19921 tcctcgcgca cgtagacgcc gccgaggccg aggcccgcgg ccttgcgcag gacgtcgacg
    19981 gggaagtgct tctcgcggtc ccactccagg gcgtacgggg cgaggtggtc cccggcgaag
    20041 tcgagggtgg tctcgaccag ggcgcgctgg tcctcgctga ggagggtgtc gtgcgtggtg
    20101 gtggcgttca tggtcgtgtg ccctcagccc atcgtcggga tggtgaagct cgccccttcg
    20161 cgcagcccct tgggccagcg cgaggtgacg gtcttggtgc gggtgtagaa acggatcgcg
    20221 tcgggcccgt gctggttgag gtcgccgaag ccggacgcct tccagccgcc gaaggtgtgg
    20281 taggcgacgg ggaccgggat cggcacgttg acgccgacca tgccgacgtt gacgcggcgg
    20341 gtgaagtcgc gtgcggtgtc gccgtcgcgc gtgaagatcg cgacgccgtt gccgaaggcg
    20401 tgctcgctcg gcaggcgcag ggcctcctcg tagtcggcgg cgcgcacgac gctgaggacg
    20461 ggcccgaaga tctcctcctg gtagatgcgc atgtcggggg tgacgcggtc gaagagcgag
    20521 ggtccggcga agaagccctt ctcgtgcccg gcgagggtga agtcccggcc gtccacgacg
    20581 agttcggctc cctcttcgac gccgagagcg acgtaggagc ggacccgggc gagggcgtcg
    20641 gggccgacga ggggcccgaa gtcggcctcg gggtcgtcgc tcgtgccgat gcgcagcccg
    20701 gcgatgcgct ccttgaggcg ggccacgagc gcgtcggccg tctcctcgcc gacgggcacg
    20761 gcgacggaga tcgccatgca gcgctcgccg gccgagccgt agccggcgcc gacgagggcg
    20821 tccacggcct ggtcgaggtc ggcgtcgggc atgacgatca tgtggttctt ggcgccgccg
    20881 aagcactggg cgcgcttgcc ctgggcggcg gcgttggcgt agatgtgcgc ggcgatgggc
    20941 gtggagccga cgaagccgag cgcctggacg cgggggtcct cgatgagggt gtccacggcg
    21001 gtgcggtcgc cgttgacgac gttgagcacc ccggcgggca gcccggcttc gaggaagagt
    21061 tcggcgaggc gcagcgggac ggaggggtcg cgctcggagg gcttgaggat gaaggcgttg
    21121 ccgcaggcga gggcgggggc cgccttccag agcgggatca tcgcggggaa gtt
//
